Binding of cytoplasmic proteins to the CD19 intracellular domain is high affinity, competitive, and multimeric

Journal of Immunology

Volumn 172, Issue 12, 2004, Pages 7556-7564

  Brooks, Stephen R ^a,e   Kirkham, Perry M ^b,e   Freeberg, Larry ^c   Carter, Robert H ^a,c,d,f  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d BIRMINGHAM VA MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; COMPLEMENTARY DNA; CYTOPLASM PROTEIN; GLUTATHIONE TRANSFERASE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE LYN; VAV PROTEIN;

ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; DAUDI CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

EID: 2942627439     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.12.7556     Document Type: Article

References (30)

1. Carter, R. H., and D. T. Fearon. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105.
2. Engel, P., L. J. Zhou, D. C. Ord, S. Sato, B. Koller, and T. F. Tedder. 1995. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. Immunity 3:39.
3. Rickert, R. C., K. Rajewsky, and J. Roes. 1995. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature 376:352.
4. Fehr, T., R. C. Rickert, B. Odermatt, J. Roes, K. Rajewsky, H. Hengartner, and R. M. Zinkernagel. 1998. Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19. J. Exp. Med. 188:145.
5. Roberts, T., and E. C. Snow. 1999. Cutting edge: recruitment of the CD19/CD21 coreceptor to B cell antigen receptor is required for antigen-mediated expression of Bcl-2 by resting and cycling hen egg lysozyme transgenic B cells. J. Immunol. 162:4377.
6. Martin, F., and J. F. Kearney. 2000. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12:39.
7. Fujimoto, M., Y. Fujimoto, J. Poe, P. Jansen, C. Lowell, A. DeFranco, and T. Tedder. 2000. CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification. Immunity 13:46.
8. Buhl, A. M., and J. C. Cambier. 1999. Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylinositol 3-kinase, are required for B cell antigen receptor-mediated activation of Bruton's tyrosine kinase. J. Immunol. 162:4438.
9. 2+ mobilization. J. Exp. Med. 186:1897.
10. Brooks, S. R., X. Li, E. J. Volanakis, and R. H. Carter. 2000. Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines. J. Immunol. 164:3123.
11. Weng, W. K., L. Jarvis, and T. W. LeBien. 1994. Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors. J. Biol. Chem. 269:32514.
12. Li, X., D. Sandoval, L. Freeberg, and R. H. Carter. 1997. Role of CD19 tyrosine 391 in synergistic activation of B lymphocytes by coligation of CD19 and membrane Ig. J. Immunol. 158:5649.
13. O'Rourke, L. M., R. Tooze, M. Turner, D. M. Sandoval, R. H. Carter, V. L. J. Tybulewicz, and D. T. Fearon. 1998. CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav. Immunity 8:635.
14. Chalupny, N. J., A. Aruffo, J. M. Esselstyn, P. Y. Chan, J. Bajorath, J. Blake, L. K. Gilliland, J. A. Ledbetter, and M. A. Tepper, 1995. Specific binding of Fyn and phosphatidylinositol 3-kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains. Eur. J. Immunol. 25:2978.
15. Gilliland, L. K., G. L. Schieven, N. A. Norris, S. B. Kanner, A. Aruffo, and J. A. Ledbetter. 1992. Lymphocyte lineage-restricted tyrosine-phosphorylated proteins that bind PLCγ1 SH2 domains. J. Biol. Chem. 267:13610.
16. Wang, Y., S. R. Brooks, X. Li, A. N. Anzelon, R. C. Rickert, and R. H. Carter. 2002. The physiologic role of CD19 cytoplasmic tyrosines. Immunity 17:501.
17. Chin, H., A. Arai, H. Wakao, R. Kamiyama, N. Miyasaka, and O. Miura. 1998. Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway. Blood 91:3734.
18. Reedijk, M., X. Liu, P. van der Geer, K. Letwin, M. D. Waterfield, T. Hunter, and T. Pawson. 1992. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J. 11:1365.
19. Wienands, J., F. Freuler, and G. Baumann. 1995. Tyrosine-phosphorylated forms of IgB, CD22, TCRζ and HOSS are major ligands for tandem SH2 domains of Syk. Int. Immunol. 7:1701.
20. Gross, B. S., S. K. Melford, and S. P. Watson. 1999. Evidence that phospholipase C-γ2 interacts with SLP-76, Syk, Lyn, LAT and the Fc receptor γ-chain after stimulation of the collagen receptor glycoprotein VI in human platelets. Eur. J. Biochem. 263:612.
21. Deckert, M., S. Tartare-Deckert, C. Couture, T. Mustelin, and A. Altman. 1996. Functional and physical interaction of Syk family kinases with the Vav protooncogene product. Immunity 5:591.
22. Lankester, A. C., P. M. Rood, G. M. van Schijndel, B. Hooibrink, A. J. Verhoeven, and R. A. van Lier. 1996. Alteration of B-cell antigen receptor signaling by CD19 co-ligation: a study with bispecific antibodies. J. Biol. Chem. 271:22326.
23. Ladbury, J. E., M. A. Lemmon, M. Zhou, J. Green, M. C. Botfield, and J. Schlessinger. 1995. Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proc. Natl. Acad. Sci. USA 92:3199.
24. Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W. G. Haser, F. King, T. Roberts, S. Ratnofsky, R. J. Lechleider, et al. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767.
25. O'Brien, R., P. Rugman, D. Renzoni, M. Layton, R. Handa, K. Hilyard, M. D. Waterfield, P. C. Driscoll, and J. E. Ladbury. 2000. Alternative modes of binding of proteins with tandem SH2 domains. Protein Sci. 9:570.
26. Ottinger, E. A., M. C. Botfield, and S. E. Shoelson. 1998. Tandem SH2 domains confer high specificity in tyrosine kinase signaling. J. Biol. Chem. 273:729.
27. Songyang, Z., S. E. Shoelson, J. McGlade, P. Olivier, T. Pawson, X. R. Bustelo, M. Barbacid, H. Sabe, H. Hanafusa, T. Yi, et al. 1994. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14:2777.
28. DeFranco, A. L., V. W. Chan, and C. A. Lowell. 1998. Positive and negative roles of the tyrosine kinase Lyn in B cell function. Semin. Immunol. 10:299.
29. Liu, X., S. R. Brodeur, G. Gish, Z. Songyang, L. C. Cantley, A. P. Laudano, and T. Pawson. 1993. Regulation of c-Src tyrosine kinase activity by the Src SH2 domain. Oncogene 8:1119.
30. Zhou, L. J., D. C. Ord, A. L. Hughes, and T. F. Tedder. 1991. Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes: conservation of the extensive cytoplasmic domain. J. Immunol. 147:1424.