-
1
-
-
0029278647
-
Lymphocyte development: Intrinsic checkpoints for maturation
-
Roth PE, DeFranco AL. Lymphocyte development: intrinsic checkpoints for maturation. Curr Biol. 5:1995;349-352.
-
(1995)
Curr Biol
, vol.5
, pp. 349-352
-
-
Roth, P.E.1
DeFranco, A.L.2
-
2
-
-
0028783322
-
Syk tyrosine kinase required for mouse viability and B-cell development
-
Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T. Syk tyrosine kinase required for mouse viability and B-cell development. Nature. 378:1995;303-306.
-
(1995)
Nature
, vol.378
, pp. 303-306
-
-
Cheng, A.M.1
Rowley, B.2
Pao, W.3
Hayday, A.4
Bolen, J.B.5
Pawson, T.6
-
3
-
-
0028889302
-
syk
-
syk. Nature. 378:1995;298-302.
-
(1995)
Nature
, vol.378
, pp. 298-302
-
-
Turner, M.1
Mee, P.J.2
Costello, P.S.3
Williams, O.4
Price, A.A.5
Duddy, L.P.6
Furlong, M.T.7
Geahlen, R.L.8
Tybulewicz, V.L.J.9
-
4
-
-
0030001124
-
Can receptor editing play an important role in normal B-cell development?
-
Nemazee D. Can receptor editing play an important role in normal B-cell development? J Autoimmun. 9:1996;259-261.
-
(1996)
J Autoimmun
, vol.9
, pp. 259-261
-
-
Nemazee, D.1
-
5
-
-
0029965138
-
Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
-
of special interest. An excellent review of the consequences of BCR signaling and the influences on it.
-
Goodnow CC. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. of special interest Proc Natl Acad Sci USA. 93:1996;2264-2271 An excellent review of the consequences of BCR signaling and the influences on it.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2264-2271
-
-
Goodnow, C.C.1
-
6
-
-
0029040199
-
Protein tyrosine kinases in the initiation of antigen receptor signaling
-
Bolen JB. Protein tyrosine kinases in the initiation of antigen receptor signaling. Curr Opin Immunol. 7:1995;306-311.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 306-311
-
-
Bolen, J.B.1
-
7
-
-
0030038840
-
Activation of Btk by a phosphorylation mechanism initiated by Src family kinases
-
Rawlings DJ, Scharenberg AM, Park H, Wahl MI, Lin S, Kato RM, Fluckiger AC, Witte ON, Kinet JP. Activation of Btk by a phosphorylation mechanism initiated by Src family kinases. Science. 271:1996;822-825.
-
(1996)
Science
, vol.271
, pp. 822-825
-
-
Rawlings, D.J.1
Scharenberg, A.M.2
Park, H.3
Wahl, M.I.4
Lin, S.5
Kato, R.M.6
Fluckiger, A.C.7
Witte, O.N.8
Kinet, J.P.9
-
8
-
-
0028926070
-
Transmembrane signaling by antigen receptors of B and T lymphocytes
-
DeFranco AL. Transmembrane signaling by antigen receptors of B and T lymphocytes. Curr Opin Cell Biol. 7:1995;163-175.
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 163-175
-
-
DeFranco, A.L.1
-
9
-
-
0030175744
-
Regulation of antigen receptor signal transduction by protein tyrosine kinases
-
Chan AC, Shaw AS. Regulation of antigen receptor signal transduction by protein tyrosine kinases. Curr Opin Immunol. 8:1996;394-401.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 394-401
-
-
Chan, A.C.1
Shaw, A.S.2
-
10
-
-
0028859279
-
Protein modules and signalling networks
-
Pawson T. Protein modules and signalling networks. Nature. 373:1995;573-580.
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
12
-
-
0028875162
-
Recognition and specificity in protein tyrosine kinase-mediated signalling
-
Songyang Z, Cantley L. Recognition and specificity in protein tyrosine kinase-mediated signalling. Trends Biochem Sci. 20:1995;470-475.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 470-475
-
-
Songyang, Z.1
Cantley, L.2
-
14
-
-
0029116007
-
Murine CD38: An immunoregulatory ectoenzyme
-
Lund F, Solvason N, Grimaldi JC, Parkhouse RM, Howard M. Murine CD38: an immunoregulatory ectoenzyme. Immunol Today. 16:1995;469-473.
-
(1995)
Immunol Today
, vol.16
, pp. 469-473
-
-
Lund, F.1
Solvason, N.2
Grimaldi, J.C.3
Parkhouse, R.M.4
Howard, M.5
-
15
-
-
0030586680
-
Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression
-
Lund FE, Yu N, Kim KM, Reth M, Howard MC. Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression. J Immunol. 157:1996;1455-1467.
-
(1996)
J Immunol
, vol.157
, pp. 1455-1467
-
-
Lund, F.E.1
Yu, N.2
Kim, K.M.3
Reth, M.4
Howard, M.C.5
-
16
-
-
0027333417
-
Structure and function of the B cell antigen receptor
-
DeFranco AL. Structure and function of the B cell antigen receptor. Annu Rev Cell Biol. 9:1993;377-410.
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 377-410
-
-
DeFranco, A.L.1
-
17
-
-
0026538635
-
Regulation of cell division of mature B cells by ionomycin and phorbol ester
-
Kim K-M, Ishigami T, Hata D, Yamaoka K, Mayumi M, Mikawa M, Mikawa H. Regulation of cell division of mature B cells by ionomycin and phorbol ester. J Immunol. 148:1992;1797-1803.
-
(1992)
J Immunol
, vol.148
, pp. 1797-1803
-
-
Kim, K.-M.1
Ishigami, T.2
Hata, D.3
Yamaoka, K.4
Mayumi, M.5
Mikawa, M.6
Mikawa, H.7
-
18
-
-
0027360451
-
Elevation of cytosolic calcium is sufficient to induce growth inhibition in a B cell lymphoma
-
Muthukkumar S, Udhayakumar V, Bondada S. Elevation of cytosolic calcium is sufficient to induce growth inhibition in a B cell lymphoma. Eur J Immunol. 23:1993;2419-2426.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2419-2426
-
-
Muthukkumar, S.1
Udhayakumar, V.2
Bondada, S.3
-
19
-
-
0030240678
-
Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells
-
of outstanding interest. An examination of the signaling events that mediate the ability of BCR signaling to protect CD40-stimulated B cells from Fas-mediated apoptosis.
-
Foote LC, Schneider TJ, Fischer GM, Wang JK, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL. Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells. of outstanding interest J Immunol. 157:1996;1878-1885 An examination of the signaling events that mediate the ability of BCR signaling to protect CD40-stimulated B cells from Fas-mediated apoptosis.
-
(1996)
J Immunol
, vol.157
, pp. 1878-1885
-
-
Foote, L.C.1
Schneider, T.J.2
Fischer, G.M.3
Wang, J.K.4
Rasmussen, B.5
Campbell, K.A.6
Lynch, D.H.7
Ju, S.T.8
Marshak-Rothstein, A.9
Rothstein, T.L.10
-
20
-
-
0029739626
-
Immunodeficiency in protein kinase C β-deficient mice
-
of outstanding interest. Characterization of antibody responses as being deficient in mice lacking PKC-β.
-
Leitges M, Schmedt C, Guinamard R, Davoust J, Schaal S, Stabel S, Tarakhovsky A. Immunodeficiency in protein kinase C β-deficient mice. of outstanding interest Science. 273:1996;788-791 Characterization of antibody responses as being deficient in mice lacking PKC-β.
-
(1996)
Science
, vol.273
, pp. 788-791
-
-
Leitges, M.1
Schmedt, C.2
Guinamard, R.3
Davoust, J.4
Schaal, S.5
Stabel, S.6
Tarakhovsky, A.7
-
21
-
-
0028812317
-
Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig
-
Xie H, Rothstein TL. Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. J Immunol. 154:1995;1717-1723.
-
(1995)
J Immunol
, vol.154
, pp. 1717-1723
-
-
Xie, H.1
Rothstein, T.L.2
-
22
-
-
0029989831
-
Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes
-
Xie H, Wang Z, Rothstein T. Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes. Cell Immunol. 169:1996;264-270.
-
(1996)
Cell Immunol
, vol.169
, pp. 264-270
-
-
Xie, H.1
Wang, Z.2
Rothstein, T.3
-
23
-
-
0026787281
-
Selective activation of p42 MAP kinase in murine B lymphoma cell lines by membrane immunoglobulin crosslinking. Evidence for protein kinase C-independent and -dependent mechanisms of activation
-
Gold MR, Sanghera JS, Stewart J, Pelech SL. Selective activation of p42 MAP kinase in murine B lymphoma cell lines by membrane immunoglobulin crosslinking. Evidence for protein kinase C-independent and -dependent mechanisms of activation. Biochem J. 286:1992;269-276.
-
(1992)
Biochem J
, vol.286
, pp. 269-276
-
-
Gold, M.R.1
Sanghera, J.S.2
Stewart, J.3
Pelech, S.L.4
-
24
-
-
0030273388
-
Protein kinase Cμ (PKCμ) associates with the B cell antigen receptor complex and regulates lymphocyte signaling
-
of special interest. This paper demonstrates that, remarkably, PKC μ associates with the BCR. Furthermore, PKCμ is activated upon BCR stimulation and this activation appears to result as a consequence of DAG production. In addition, the experiments described suggest that a target of PKCμ is Syk, reflecting feedback inhibition.
-
Sidorenko SP, Law C-L, Klaus SJ, Chandran KA, Takata M, Kurosaki T, Clark EA. Protein kinase Cμ (PKCμ) associates with the B cell antigen receptor complex and regulates lymphocyte signaling. of special interest Immunity. 5:1996;353-363 This paper demonstrates that, remarkably, PKC μ associates with the BCR. Furthermore, PKCμ is activated upon BCR stimulation and this activation appears to result as a consequence of DAG production. In addition, the experiments described suggest that a target of PKCμ is Syk, reflecting feedback inhibition.
-
(1996)
Immunity
, vol.5
, pp. 353-363
-
-
Sidorenko, S.P.1
Law, C.-L.2
Klaus, S.J.3
Chandran, K.A.4
Takata, M.5
Kurosaki, T.6
Clark, E.A.7
-
25
-
-
0028804861
-
Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes
-
Valentine MA, Czernik AJ, Rachie N, Hidaka H, Fisher CL, Cambier JC, Bomsztyk K. Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes. J Exp Med. 182:1995;1943-1949.
-
(1995)
J Exp Med
, vol.182
, pp. 1943-1949
-
-
Valentine, M.A.1
Czernik, A.J.2
Rachie, N.3
Hidaka, H.4
Fisher, C.L.5
Cambier, J.C.6
Bomsztyk, K.7
-
26
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber SL, Crabtree GR. The mechanism of action of cyclosporin A and FK506. Immunol Today. 13:1992;136-142.
-
(1992)
Immunol Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
27
-
-
0025761215
-
Ligation of membrane Ig leads to calcium-mediated phosphorylation of the proto-oncogene product Ets-1
-
Fisher CL, Ghysdael J, Cambier JC. Ligation of membrane Ig leads to calcium-mediated phosphorylation of the proto-oncogene product Ets-1. J Immunol. 146:1991;1743-1749.
-
(1991)
J Immunol
, vol.146
, pp. 1743-1749
-
-
Fisher, C.L.1
Ghysdael, J.2
Cambier, J.C.3
-
28
-
-
0028445321
-
Cyclosporin-A sensitive induction of NF-AT in murine B cells
-
Venkataraman L, Francis DA, Wang Z, Liu J, Rothstein TL, Sen R. Cyclosporin-A sensitive induction of NF-AT in murine B cells. Immunity. 1:1994;189-196.
-
(1994)
Immunity
, vol.1
, pp. 189-196
-
-
Venkataraman, L.1
Francis, D.A.2
Wang, Z.3
Liu, J.4
Rothstein, T.L.5
Sen, R.6
-
29
-
-
0028286517
-
Cyclosporin A and FK506 inhibit activation-induced death in the murine WEHI-231 B cell line
-
Genestier L, Dearden-Badet MT, Bonnefoy-Berard N, Lizard G, Revillard JP. Cyclosporin A and FK506 inhibit activation-induced death in the murine WEHI-231 B cell line. Cell Immunol. 155:1994;283-291.
-
(1994)
Cell Immunol
, vol.155
, pp. 283-291
-
-
Genestier, L.1
Dearden-Badet, M.T.2
Bonnefoy-Berard, N.3
Lizard, G.4
Revillard, J.P.5
-
30
-
-
0022542159
-
Effects of cyclosporin on responses of murine B cells to T cell-derived lymphokines
-
O'Garra A, Warren DJ, Holman M, Popham AM, Sanderson CJ, Klaus GG. Effects of cyclosporin on responses of murine B cells to T cell-derived lymphokines. J Immunol. 137:1986;2220-2224.
-
(1986)
J Immunol
, vol.137
, pp. 2220-2224
-
-
O'Garra, A.1
Warren, D.J.2
Holman, M.3
Popham, A.M.4
Sanderson, C.J.5
Klaus, G.G.6
-
31
-
-
0028362292
-
Signaling pathways activated by protein tyrosine phosphorylation in lymphocytes
-
DeFranco AL. Signaling pathways activated by protein tyrosine phosphorylation in lymphocytes. Curr Opin Immunol. 6:1994;364-371.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 364-371
-
-
DeFranco, A.L.1
-
32
-
-
0028180858
-
2+ mobilization through distinct pathways
-
2+ mobilization through distinct pathways. EMBO J. 13:1994;1341-1349.
-
(1994)
EMBO J
, vol.13
, pp. 1341-1349
-
-
Takata, M.1
Sabe, H.2
Hata, A.3
Inazu, T.4
Homma, Y.5
Nukada, T.6
Yamamura, H.7
Kurosaki, T.8
-
33
-
-
0030018304
-
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ2
-
of outstanding interest. Demonstrates a critical role for Btk in the activation of PLC-γ by the BCR.
-
Takata M, Kurosaki T. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ2. of outstanding interest J Exp Med. 184:1996;31-40 Demonstrates a critical role for Btk in the activation of PLC-γ by the BCR.
-
(1996)
J Exp Med
, vol.184
, pp. 31-40
-
-
Takata, M.1
Kurosaki, T.2
-
34
-
-
0030047811
-
CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-γ1 upon B cell activation
-
Law CL, Sidorenko SP, Chandran KA, Zhao Z, Shen SH, Fischer EH, Clark EA. CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-γ1 upon B cell activation. J Exp Med. 183:1996;547-560.
-
(1996)
J Exp Med
, vol.183
, pp. 547-560
-
-
Law, C.L.1
Sidorenko, S.P.2
Chandran, K.A.3
Zhao, Z.4
Shen, S.H.5
Fischer, E.H.6
Clark, E.A.7
-
35
-
-
0029909049
-
Hyperresponsive B cells in CD22-deficient mice
-
of special interest. Characterization of the B cells from mice lacking CD22. BCR-induced calcium elevation is enhanced in the absence of CD22. In [36-38] antibody or proliferative responses to BCR engagement are found to be decreased. Thus, CD22 functions both positively and negatively in modulating responses to antigen.
-
O'Keefe TL, Williams GT, Davies SL, Neuberger MS. Hyperresponsive B cells in CD22-deficient mice. of special interest Science. 274:1996;798-801 Characterization of the B cells from mice lacking CD22. BCR-induced calcium elevation is enhanced in the absence of CD22. In [36-38] antibody or proliferative responses to BCR engagement are found to be decreased. Thus, CD22 functions both positively and negatively in modulating responses to antigen.
-
(1996)
Science
, vol.274
, pp. 798-801
-
-
O'Keefe, T.L.1
Williams, G.T.2
Davies, S.L.3
Neuberger, M.S.4
-
36
-
-
0030467610
-
CD22 regulates thymus-independent responses and the lifespan of B cells
-
of special interest. See annotation [35].
-
Otipoby KL, Andersson KB, Draves KE, Klaus SJ, Farr AG, Kerner JD, Perlmutter RM, Law CL, Clark EA. CD22 regulates thymus-independent responses and the lifespan of B cells. of special interest Nature. 384:1996;634-637 See annotation [35].
-
(1996)
Nature
, vol.384
, pp. 634-637
-
-
Otipoby, K.L.1
Andersson, K.B.2
Draves, K.E.3
Klaus, S.J.4
Farr, A.G.5
Kerner, J.D.6
Perlmutter, R.M.7
Law, C.L.8
Clark, E.A.9
-
37
-
-
0030499431
-
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
-
of special interest. See annotation [35].
-
Sato S, Miller AS, Inaoki M, Bock CB, Jansen PJ, Tang ML, Tedder TF. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. of special interest Immunity. 5:1996;551-562 See annotation [35].
-
(1996)
Immunity
, vol.5
, pp. 551-562
-
-
Sato, S.1
Miller, A.S.2
Inaoki, M.3
Bock, C.B.4
Jansen, P.J.5
Tang, M.L.6
Tedder, T.F.7
-
38
-
-
0031080328
-
CD22 is a negative regulator of B-cell receptor signalling
-
of special interest. See annotation [35].
-
Nitschke L, Carsetti R, Ocker B, Kohler G, Lamers MC. CD22 is a negative regulator of B-cell receptor signalling. of special interest Curr Biol. 7:1997;133-143 See annotation [35].
-
(1997)
Curr Biol
, vol.7
, pp. 133-143
-
-
Nitschke, L.1
Carsetti, R.2
Ocker, B.3
Kohler, G.4
Lamers, M.C.5
-
39
-
-
0028977990
-
syk with the src-homology-2 (SH2) domains of PLC-γ1 in B lymphocytes
-
syk with the src-homology-2 (SH2) domains of PLC-γ1 in B lymphocytes. J Biol Chem. 270:1995;11806-11811.
-
(1995)
J Biol Chem
, vol.270
, pp. 11806-11811
-
-
Sillman, A.L.1
Monroe, J.G.2
-
40
-
-
0029670081
-
Phospholipase C-γ1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
-
Law CL, Chandran KA, Sidorenko SP, Clark EA. Phospholipase C-γ1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk. Mol Cell Biol. 16:1996;1305-1315.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1305-1315
-
-
Law, C.L.1
Chandran, K.A.2
Sidorenko, S.P.3
Clark, E.A.4
-
41
-
-
0028180585
-
GRB2 and phospholipase C-γ1 associate with a 36- To 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation
-
Sieh M, Batzer A, Schlessinger J, Weiss A. GRB2 and phospholipase C-γ1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Mol Cell Biol. 14:1994;4435-4442.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4435-4442
-
-
Sieh, M.1
Batzer, A.2
Schlessinger, J.3
Weiss, A.4
-
42
-
-
0029999327
-
Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C γ1 activation in T cells
-
Motto DG, Musci MA, Ross SE, Koretzky GA. Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C γ1 activation in T cells. Mol Cell Biol. 16:1996;2823-2829.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2823-2829
-
-
Motto, D.G.1
Musci, M.A.2
Ross, S.E.3
Koretzky, G.A.4
-
43
-
-
0029587597
-
Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase Cγ1, Grb2, and phosphatidylinositol 3-kinase
-
Huang X, Li Y, Tanaka K, Moore KG, Hayashi JI. Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase Cγ1, Grb2, and phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA. 92:1995;11618-11622.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11618-11622
-
-
Huang, X.1
Li, Y.2
Tanaka, K.3
Moore, K.G.4
Hayashi, J.I.5
-
46
-
-
0028869818
-
A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor crosslinking in B lymphocytes
-
McMahon SB, Monroe JG. A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor crosslinking in B lymphocytes. Mol Cell Biol. 15:1995;1086-1093.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1086-1093
-
-
McMahon, S.B.1
Monroe, J.G.2
-
47
-
-
0029935418
-
Regulation of transcription by MAP kinase cascades
-
Treisman R. Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol. 8:1996;205-215.
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 205-215
-
-
Treisman, R.1
-
48
-
-
0029971763
-
A role for EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes
-
of special interest. Demonstrates that the CD44 gene is activated by the Egr1 transcription factor in BCR-stimulated B cells.
-
Maltzman J, Monroe JG. A role for EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes. of special interest Mol Cell Biol. 16:1996;2283-2294 Demonstrates that the CD44 gene is activated by the Egr1 transcription factor in BCR-stimulated B cells.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2283-2294
-
-
Maltzman, J.1
Monroe, J.G.2
-
49
-
-
0029864377
-
Transcriptional regulation of the ICAM-1 gene in antigen receptor and phorbol ester stimulated B lymphocytes: Role for transcription factor EGR1
-
of special interest. Demonstrates that the ICAM-1 gene is activated by the Egr1 transcription factor in BCR-stimulated B cells.
-
Maltzman J, Monroe JG. Transcriptional regulation of the ICAM-1 gene in antigen receptor and phorbol ester stimulated B lymphocytes: role for transcription factor EGR1. of special interest J Exp Med. 183:1996;1747-1759 Demonstrates that the ICAM-1 gene is activated by the Egr1 transcription factor in BCR-stimulated B cells.
-
(1996)
J Exp Med
, vol.183
, pp. 1747-1759
-
-
Maltzman, J.1
Monroe, J.G.2
-
50
-
-
0028985453
-
ras pathway couples antigen receptor stimulation to induction of the primary response gene egr-1 in B lymphocytes
-
ras pathway couples antigen receptor stimulation to induction of the primary response gene egr-1 in B lymphocytes. J Exp Med. 181:1995;417-422.
-
(1995)
J Exp Med
, vol.181
, pp. 417-422
-
-
McMahon, S.B.1
Monroe, J.G.2
-
51
-
-
0030003647
-
Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase
-
2 hydrolysis was not, perhaps suggesting that one or more additional lymphoid-specific signaling components are required for this response.
-
2 hydrolysis was not, perhaps suggesting that one or more additional lymphoid-specific signaling components are required for this response.
-
(1996)
J Biol Chem
, vol.271
, pp. 6458-6466
-
-
Richards, J.D.1
Gold, M.R.2
Hourihane, S.L.3
DeFranco, A.L.4
Matsuuchi, L.5
-
52
-
-
0028263656
-
res oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1 and a 145-kDa tyrosine-phosphorylated protein
-
res oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1 and a 145-kDa tyrosine-phosphorylated protein. J Immunol. 153:1994;623-636.
-
(1994)
J Immunol
, vol.153
, pp. 623-636
-
-
Saxton, T.M.1
Van Oostveen, I.2
Bowtell, D.3
Aebersold, R.4
Gold, M.R.5
-
53
-
-
0028089709
-
B cell antigen receptor cross-linking induces tyrosine phosphorylation and membrane translocation of a multimeric Shc complex that is augmented by CD19 co-ligation
-
Lankester AC, van Schijndel GM, Rood PM, Verhoeven AJ, van Lier RA. B cell antigen receptor cross-linking induces tyrosine phosphorylation and membrane translocation of a multimeric Shc complex that is augmented by CD19 co-ligation. Eur J Immunol. 24:1994;2818-2825.
-
(1994)
Eur J Immunol
, vol.24
, pp. 2818-2825
-
-
Lankester, A.C.1
Van Schijndel, G.M.2
Rood, P.M.3
Verhoeven, A.J.4
Van Lier, R.A.5
-
54
-
-
0028147237
-
B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins
-
Smit L, de Vries-Smits AMM, Bos JL, Borst J. B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins. J Biol Chem. 269:1994;20209-20212.
-
(1994)
J Biol Chem
, vol.269
, pp. 20209-20212
-
-
Smit, L.1
De Vries-Smits, A.M.M.2
Bos, J.L.3
Borst, J.4
-
55
-
-
0028832658
-
Signal transduction in T lymphocytes using a conditional allele of Sos
-
Holsinger LJ, Spencer DM, Austin DJ, Schreiber SL, Crabtree GR. Signal transduction in T lymphocytes using a conditional allele of Sos. Proc Natl Acad Sci USA. 92:1995;9810-9814.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9810-9814
-
-
Holsinger, L.J.1
Spencer, D.M.2
Austin, D.J.3
Schreiber, S.L.4
Crabtree, G.R.5
-
56
-
-
0027724634
-
Interaction of Shc with the ζ chain of the T cell receptor upon T cell activation
-
Ravichandran KS, Lee KK, Songyang Z, Cantley LC, Burn P, Burakoff SJ. Interaction of Shc with the ζ chain of the T cell receptor upon T cell activation. Science. 262:1993;902-905.
-
(1993)
Science
, vol.262
, pp. 902-905
-
-
Ravichandran, K.S.1
Lee, K.K.2
Songyang, Z.3
Cantley, L.C.4
Burn, P.5
Burakoff, S.J.6
-
57
-
-
0028023767
-
In vitro characterization of major ligands for Src homology 2 domains derived from protein tyrosine kinases, from the adapter protein SHC and from GTPase-activating protein in Ramos B cells
-
Baumann G, Maier D, Freuler F, Tschopp C, Baudisch K, Wienands J. In vitro characterization of major ligands for Src homology 2 domains derived from protein tyrosine kinases, from the adapter protein SHC and from GTPase-activating protein in Ramos B cells. Eur J Immunol. 24:1994;1799-1807.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1799-1807
-
-
Baumann, G.1
Maier, D.2
Freuler, F.3
Tschopp, C.4
Baudisch, K.5
Wienands, J.6
-
58
-
-
0029810421
-
Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor
-
D'Ambrosio D, Hippen KL, Cambier JC. Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor. Eur J Immunol. 26:1996;1960-1965.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1960-1965
-
-
D'Ambrosio, D.1
Hippen, K.L.2
Cambier, J.C.3
-
59
-
-
0028901649
-
Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling
-
Nagai K, Takata M, Yamamura H, Kurosaki T. Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling. J Biol Chem. 270:1995;6824-6829.
-
(1995)
J Biol Chem
, vol.270
, pp. 6824-6829
-
-
Nagai, K.1
Takata, M.2
Yamamura, H.3
Kurosaki, T.4
-
61
-
-
0029876948
-
Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G
-
Reedquist KA, Fukazawa T, Panchamoorthy G, Langdon WY, Shoelson SE, Druker BJ, Band H. Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G. J Biol Chem. 271:1996;8435-8442.
-
(1996)
J Biol Chem
, vol.271
, pp. 8435-8442
-
-
Reedquist, K.A.1
Fukazawa, T.2
Panchamoorthy, G.3
Langdon, W.Y.4
Shoelson, S.E.5
Druker, B.J.6
Band, H.7
-
62
-
-
0030962699
-
Shc possesses two Grb2 binding sites needed for the efficient formation of complexes with SOS in B lymphocytes
-
in press
-
Harmer S, DeFranco AL. Shc possesses two Grb2 binding sites needed for the efficient formation of complexes with SOS in B lymphocytes. Mol Cell Biol. 1997;. in press.
-
(1997)
Mol Cell Biol
-
-
Harmer, S.1
DeFranco, A.L.2
-
63
-
-
0028137615
-
Activators and effectors of ras p21 proteins
-
McCormick F. Activators and effectors of ras p21 proteins. Curr Opin Genet Dev. 4:1994;71-76.
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 71-76
-
-
McCormick, F.1
-
64
-
-
0030221148
-
Interactions between Ras proteins and their effectors
-
McCormick F, Wittinghofer A. Interactions between Ras proteins and their effectors. Curr Opin Biotechnol. 7:1996;449-456.
-
(1996)
Curr Opin Biotechnol
, vol.7
, pp. 449-456
-
-
McCormick, F.1
Wittinghofer, A.2
-
67
-
-
0031459864
-
dok: A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
-
dok: a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell. 88:1997;197-204.
-
(1997)
Cell
, vol.88
, pp. 197-204
-
-
Carpino, N.1
Wisniewski, D.2
Strife, A.3
Marshak, D.4
Kobayashi, R.5
Stillman, B.6
Clarkson, B.7
-
68
-
-
0031444245
-
Identification of the Abl- And rasGAP-associated 62 kDa protein as a docking protein Dok
-
Yamanashi Y, Baltimore D. Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein Dok. Cell. 88:1997;205-211.
-
(1997)
Cell
, vol.88
, pp. 205-211
-
-
Yamanashi, Y.1
Baltimore, D.2
-
69
-
-
0030068527
-
Phosphatidylinositol-3-kinase activity is required for the anti-Ig-mediated growth inhibition of a human B-lymphoma cell line
-
of special interest. Wortmannin is found to inhibit BCR-induced growth inhibition in the RL B cell line indicating an important role for PI3-K.
-
Beckwith M, Fenton RG, Katona IM, Longo DL. Phosphatidylinositol-3-kinase activity is required for the anti-Ig-mediated growth inhibition of a human B-lymphoma cell line. of special interest Blood. 87:1996;202-210 Wortmannin is found to inhibit BCR-induced growth inhibition in the RL B cell line indicating an important role for PI3-K.
-
(1996)
Blood
, vol.87
, pp. 202-210
-
-
Beckwith, M.1
Fenton, R.G.2
Katona, I.M.3
Longo, D.L.4
-
70
-
-
0027169534
-
CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase
-
Tuveson DA, Carter RH, Soltoff SP, Fearon DT. CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase. Science. 260:1993;986-989.
-
(1993)
Science
, vol.260
, pp. 986-989
-
-
Tuveson, D.A.1
Carter, R.H.2
Soltoff, S.P.3
Fearon, D.T.4
-
71
-
-
0028958669
-
The CD19/CR2/TAPA-1 complex of B lymphocytes: Linking natural to acquired immunity
-
Fearon DT, Carter RH. The CD19/CR2/TAPA-1 complex of B lymphocytes: Linking natural to acquired immunity. Annu Rev Immunol. 13:1995;127-149.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 127-149
-
-
Fearon, D.T.1
Carter, R.H.2
-
72
-
-
0028198388
-
Activation of phosphatidylinositol-3'kinase by Src-family kinase SH3 binding to the p85 subunit
-
Pleiman CM, Hertz WM, Cambier JC. Activation of phosphatidylinositol-3'kinase by Src-family kinase SH3 binding to the p85 subunit. Science. 263:1994;1609-1612.
-
(1994)
Science
, vol.263
, pp. 1609-1612
-
-
Pleiman, C.M.1
Hertz, W.M.2
Cambier, J.C.3
-
73
-
-
0026593547
-
Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling
-
Yamanashi Y, Fukui Y, Wongsasant B, Kinoshita Y, Ichimori Y, Toyoshima K, Yamamoto T. Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci USA. 89:1992;1118-1122.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1118-1122
-
-
Yamanashi, Y.1
Fukui, Y.2
Wongsasant, B.3
Kinoshita, Y.4
Ichimori, Y.5
Toyoshima, K.6
Yamamoto, T.7
-
75
-
-
0000387536
-
B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn
-
Law DA, Chan VWF, Datta SK, DeFranco AL. B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn. Curr Biol. 3:1993;645-657.
-
(1993)
Curr Biol
, vol.3
, pp. 645-657
-
-
Law, D.A.1
Chan, V.W.F.2
Datta, S.K.3
DeFranco, A.L.4
-
76
-
-
0029907533
-
The protein product of the proto-oncogene c-cbl forms a complex with phosphatidylinositol 3-kinase p85 and CD19 in anti-IgM-stimulated human B lymphoma cells
-
of special interest. Evidence for the association of Cbl with CD19, possibly in a multimeric complex involving PI3-K.
-
Beckwith M, Jorgensen G, Longo DL. The protein product of the proto-oncogene c-cbl forms a complex with phosphatidylinositol 3-kinase p85 and CD19 in anti-IgM-stimulated human B lymphoma cells. of special interest Blood. 88:1996;3502-3507 Evidence for the association of Cbl with CD19, possibly in a multimeric complex involving PI3-K.
-
(1996)
Blood
, vol.88
, pp. 3502-3507
-
-
Beckwith, M.1
Jorgensen, G.2
Longo, D.L.3
-
77
-
-
0028002840
-
Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells
-
Gold MR, Aebersold R. Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells. J Immunol. 152:1994;42-50.
-
(1994)
J Immunol
, vol.152
, pp. 42-50
-
-
Gold, M.R.1
Aebersold, R.2
-
78
-
-
0030066326
-
Activation-induced association of a 145-kDa tyrosine-phosphorylated protein with Shc and Syk in B lymphocytes and macrophages
-
SHIP and its association with Shc and with Syk
-
SHIP and its association with Shc and with Syk.
-
(1996)
J Biol Chem
, vol.271
, pp. 1145-1152
-
-
Crowley, M.T.1
Harmer, S.L.2
DeFranco, A.L.3
-
79
-
-
0030587116
-
Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP
-
of outstanding interest. Demonstrates that SHIP is more strongly phosphorylated when the BCR is co-ligated to FcγRIIB1 than when the BCR is simply cross-linked. This result suggests that SHIP participates in negative regulation by FcγRIIB1.
-
Chacko GW, Tridandapani S, Damen JE, Liu L, Krystal G, Coggeshall KM. Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP. of outstanding interest J Immunol. 157:1996;2234-2238 Demonstrates that SHIP is more strongly phosphorylated when the BCR is co-ligated to FcγRIIB1 than when the BCR is simply cross-linked. This result suggests that SHIP participates in negative regulation by FcγRIIB1.
-
(1996)
J Immunol
, vol.157
, pp. 2234-2238
-
-
Chacko, G.W.1
Tridandapani, S.2
Damen, J.E.3
Liu, L.4
Krystal, G.5
Coggeshall, K.M.6
-
80
-
-
10544219605
-
Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase
-
3, rather than to other phosphoinositides.
-
3, rather than to other phosphoinositides.
-
(1996)
EMBO J
, vol.15
, pp. 6241-6250
-
-
Salim, K.1
Bottomley, M.J.2
Querfurth, E.3
Zvelebil, M.J.4
Gout, I.5
Scaife, R.6
Margolis, R.L.7
Gigg, R.8
Smith, C.I.E.9
Driscoll, P.C.10
-
81
-
-
0029786742
-
Negative signaling via FcγRIIB1 in B cells blocks phospholipase Cγ2 tyrosine phosphorylation but not Syk or Lyn activation
-
2 breakdown induced by the BCR and demonstrates it is not due to a general inhibition of BCR signaling.
-
2 breakdown induced by the BCR and demonstrates it is not due to a general inhibition of BCR signaling.
-
(1996)
J Biol Chem
, vol.271
, pp. 20182-20186
-
-
Sarkar, S.1
Schlottmann, K.2
Cooney, D.3
Coggeshall, K.M.4
-
82
-
-
0022319106
-
Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptor
-
Bijsterbosch MK, Klaus GGB. Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptor. J Exp Med. 162:1985;1825-1836.
-
(1985)
J Exp Med
, vol.162
, pp. 1825-1836
-
-
Bijsterbosch, M.K.1
Klaus, G.G.B.2
-
83
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke TF, Kaplan DR, Cantley LC, Toker A. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science. 275:1997;665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
84
-
-
0031015986
-
A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain
-
Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol Cell Biol. 17:1997;338-344.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 338-344
-
-
Klippel, A.1
Kavanaugh, W.M.2
Pot, D.3
Williams, L.T.4
-
85
-
-
0030250114
-
Complex complexes: Signaling at the TCR
-
Wange RL, Samelson LE. Complex complexes: signaling at the TCR. Immunity. 5:1996;197-205.
-
(1996)
Immunity
, vol.5
, pp. 197-205
-
-
Wange, R.L.1
Samelson, L.E.2
-
86
-
-
10144243337
-
A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells
-
Lupher ML Jr, Reedquist KA, Miyake S, Langdon WY, Band H. A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells. J Biol Chem. 271:1996;24063-24068.
-
(1996)
J Biol Chem
, vol.271
, pp. 24063-24068
-
-
Lupher M.L., Jr.1
Reedquist, K.A.2
Miyake, S.3
Langdon, W.Y.4
Band, H.5
-
87
-
-
0029098389
-
The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase
-
Cory GO, Lovering RC, Hinshelwood S, MacCarthy-Morrogh L, Levinsky RJ, Kinnon C. The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase. J Exp Med. 182:1995;611-615.
-
(1995)
J Exp Med
, vol.182
, pp. 611-615
-
-
Cory, G.O.1
Lovering, R.C.2
Hinshelwood, S.3
MacCarthy-Morrogh, L.4
Levinsky, R.J.5
Kinnon, C.6
-
88
-
-
0029117423
-
Specific association of the β isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl
-
Hartley D, Meisner H, Corvera S. Specific association of the β isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. J Biol Chem. 270:1995;18260-18263.
-
(1995)
J Biol Chem
, vol.270
, pp. 18260-18263
-
-
Hartley, D.1
Meisner, H.2
Corvera, S.3
-
90
-
-
0029671073
-
cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase
-
cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J Biol Chem. 271:1996;3187-3194.
-
(1996)
J Biol Chem
, vol.271
, pp. 3187-3194
-
-
Panchamoorthy, G.1
Fukazawa, T.2
Miyake, S.3
Soltoff, S.4
Reedquist, D.5
Druker, B.6
Shoelson, S.7
Cantley, L.8
Band, H.9
-
91
-
-
0029928127
-
Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors
-
of outstanding interest. of special interest. This reference, along with [92] establishes a role for Cbl in the formation of complexes containing the nucleotide exchange factor C3G, providing a model for how Cbl might function as an inhibitor of the Ras pathway.
-
of outstanding interest Smit L, van der Horst G, Borst J. Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors. of special interest J Biol Chem. 271:1996;8564-8569 This reference, along with [92] establishes a role for Cbl in the formation of complexes containing the nucleotide exchange factor C3G, providing a model for how Cbl might function as an inhibitor of the Ras pathway.
-
(1996)
J Biol Chem
, vol.271
, pp. 8564-8569
-
-
Smit, L.1
Van Der Horst, G.2
Borst, J.3
-
92
-
-
0029768637
-
B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins
-
of special interest. of outstanding interest. See annotation [91].
-
of special interest Ingham RJ, Krebs DL, Barbazuk SM, Turck CW, Hirai H, Matsuda M, Gold MR. B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins. of outstanding interest J Biol Chem. 271:1996;32306-32314 See annotation [91].
-
(1996)
J Biol Chem
, vol.271
, pp. 32306-32314
-
-
Ingham, R.J.1
Krebs, D.L.2
Barbazuk, S.M.3
Turck, C.W.4
Hirai, H.5
Matsuda, M.6
Gold, M.R.7
-
93
-
-
0029124883
-
Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl
-
Yoon CH, Lee J, Jongeward GD, Sternberg PW. Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science. 269:1995;1102-1105.
-
(1995)
Science
, vol.269
, pp. 1102-1105
-
-
Yoon, C.H.1
Lee, J.2
Jongeward, G.D.3
Sternberg, P.W.4
-
94
-
-
0029670779
-
lyn, in the B cell antigen receptor-mediated signaling
-
of special interest. Demonstrates that Lyn is required in the DT-40 chicken B cell line for the BCR to phosphorylate Cbl.
-
lyn, in the B cell antigen receptor-mediated signaling. of special interest J Exp Med. 183:1996;675-680 Demonstrates that Lyn is required in the DT-40 chicken B cell line for the BCR to phosphorylate Cbl.
-
(1996)
J Exp Med
, vol.183
, pp. 675-680
-
-
Tezuka, T.1
Umemori, H.2
Fusaki, N.3
Yagi, T.4
Takata, M.5
Kurosaki, T.6
Yamamoto, T.7
-
95
-
-
0342596009
-
Vav: Function and regulation in hematopoietic cell signaling
-
of special interest. A thoughtful and balanced review of the function of Vav and its role in antigen receptor signaling.
-
Bonnefoy-Berard N, Munshi A, Yron I, Wu S, Collins TL, Deckert M, Shalom-Barak T, Giampa L, Herbert E, Hernandez J, et al. Vav: function and regulation in hematopoietic cell signaling. of special interest Stem Cells. 14:1996;250-268 A thoughtful and balanced review of the function of Vav and its role in antigen receptor signaling.
-
(1996)
Stem Cells
, vol.14
, pp. 250-268
-
-
Bonnefoy-Berard, N.1
Munshi, A.2
Yron, I.3
Wu, S.4
Collins, T.L.5
Deckert, M.6
Shalom-Barak, T.7
Giampa, L.8
Herbert, E.9
Hernandez, J.10
-
96
-
-
0030466893
-
Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases
-
Olson MF, Pasteris NG, Gorski JL, Hau A. Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases. Curr Biol. 6:1996;1628-1633.
-
(1996)
Curr Biol
, vol.6
, pp. 1628-1633
-
-
Olson, M.F.1
Pasteris, N.G.2
Gorski, J.L.3
Hau, A.4
-
97
-
-
0031033292
-
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
-
Crespo P, Schuebel KE, Ostrom AA, Gutkind JS, Bustelo XR. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature. 385:1997;169-172.
-
(1997)
Nature
, vol.385
, pp. 169-172
-
-
Crespo, P.1
Schuebel, K.E.2
Ostrom, A.A.3
Gutkind, J.S.4
Bustelo, X.R.5
-
98
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem. 271:1996;24313-24316.
-
(1996)
J Biol Chem
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
99
-
-
0030069905
-
Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases
-
of special interest. Demonstrates that CD40 and the BCR activate the JNK and p38 MAP kinases. See also [100].
-
Berberich I, Shu G, Siebelt F, Woodgett JR, Kyriakis JM, Clark EA. Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases. of special interest EMBO J. 15:1996;92-101 Demonstrates that CD40 and the BCR activate the JNK and p38 MAP kinases. See also [100].
-
(1996)
EMBO J
, vol.15
, pp. 92-101
-
-
Berberich, I.1
Shu, G.2
Siebelt, F.3
Woodgett, J.R.4
Kyriakis, J.M.5
Clark, E.A.6
-
100
-
-
0030587829
-
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor
-
of special interest. See annotation [99].
-
Sutherland CL, Heath AW, Pelech SL, Young PR, Gold MR. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. of special interest J Immunol. 157:1996;3381-3390 See annotation [99].
-
(1996)
J Immunol
, vol.157
, pp. 3381-3390
-
-
Sutherland, C.L.1
Heath, A.W.2
Pelech, S.L.3
Young, P.R.4
Gold, M.R.5
-
101
-
-
0030459830
-
Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes
-
of special interest. Evidence for a role for JNK and p38 MAP kinases in BCR-induced apoptosis.
-
Graves JD, Draves KE, Craxton A, Saklatvala J, Krebs EG, Clark EA. Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes. of special interest Proc Natl Acad Sci USA. 93:1996;13814-13818 Evidence for a role for JNK and p38 MAP kinases in BCR-induced apoptosis.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13814-13818
-
-
Graves, J.D.1
Draves, K.E.2
Craxton, A.3
Saklatvala, J.4
Krebs, E.G.5
Clark, E.A.6
-
102
-
-
0028104466
-
Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis
-
Tanguay DA, Dickinson JA, McManus BJ, Huo L, Rothstein TL, Chiles TC. Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis. Cell Immunol. 158:1994;281-291.
-
(1994)
Cell Immunol
, vol.158
, pp. 281-291
-
-
Tanguay, D.A.1
Dickinson, J.A.2
McManus, B.J.3
Huo, L.4
Rothstein, T.L.5
Chiles, T.C.6
-
104
-
-
0029041568
-
Transcriptional regulation of the IL-2 gene
-
Jain J, Loh C, Rao A. Transcriptional regulation of the IL-2 gene. Curr Opin Immunol. 7:1995;333-342.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 333-342
-
-
Jain, J.1
Loh, C.2
Rao, A.3
-
105
-
-
0030499383
-
Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product
-
of special interest. Provides evidence for an important functional interaction between Syk and Vav.
-
Deckert M, Tartare-Deckert S, Couture C, Mustelin T, Altman A. Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product. of special interest Immunity. 5:1996;591-604 Provides evidence for an important functional interaction between Syk and Vav.
-
(1996)
Immunity
, vol.5
, pp. 591-604
-
-
Deckert, M.1
Tartare-Deckert, S.2
Couture, C.3
Mustelin, T.4
Altman, A.5
-
106
-
-
0028597993
-
Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors
-
Weng W-K, Jarvis L, LeBien TW. Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors. J Biol Chem. 269:1994;32514-32521.
-
(1994)
J Biol Chem
, vol.269
, pp. 32514-32521
-
-
Weng, W.-K.1
Jarvis, L.2
Lebien, T.W.3
-
107
-
-
0027469994
-
Identification of HS1 protein as a major substate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling
-
Yamanashi Y, Okada M, Semba T, Yamori T, Umemori H, Tsunasawa S, Toyoshima K, Kitamura D, Watanabe T, Yamamoto T. Identification of HS1 protein as a major substate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci USA. 90:1993;3631-3635.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3631-3635
-
-
Yamanashi, Y.1
Okada, M.2
Semba, T.3
Yamori, T.4
Umemori, H.5
Tsunasawa, S.6
Toyoshima, K.7
Kitamura, D.8
Watanabe, T.9
Yamamoto, T.10
-
108
-
-
0029151248
-
Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases
-
Taniuchi I, Kitamura D, Maekawa Y, Fukuda T, Kishi H, Watanabe T. Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases. EMBO J. 14:1995;3664-3678.
-
(1995)
EMBO J
, vol.14
, pp. 3664-3678
-
-
Taniuchi, I.1
Kitamura, D.2
Maekawa, Y.3
Fukuda, T.4
Kishi, H.5
Watanabe, T.6
-
109
-
-
0029086739
-
Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate
-
Fukuda T, Kitamura D, Taniuchi I, Maekawa Y, Benghamou LE, Sarthou P, Watanabe T. Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate. Proc Natl Acad Sci USA. 92:1995;7302-7306.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7302-7306
-
-
Fukuda, T.1
Kitamura, D.2
Taniuchi, I.3
Maekawa, Y.4
Benghamou, L.E.5
Sarthou, P.6
Watanabe, T.7
-
110
-
-
0030593030
-
C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
-
of outstanding interest. Demonstrates the dramatic enhancing effect of co-engagement of the BCR and CR2 on B cell antibody responses in vivo.
-
Dempsey PW, Allison MED, Akkaraju S, Goodnow CC, Fearon DT. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. of outstanding interest Science. 271:1996;348-350 Demonstrates the dramatic enhancing effect of co-engagement of the BCR and CR2 on B cell antibody responses in vivo.
-
(1996)
Science
, vol.271
, pp. 348-350
-
-
Dempsey, P.W.1
Allison, M.E.D.2
Akkaraju, S.3
Goodnow, C.C.4
Fearon, D.T.5
-
111
-
-
0029835940
-
Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB
-
of outstanding interest. Demonstrates that SHIP binds to and is an important mediator of the negative signaling effects of FcγRIIB.
-
Ono M, Bolland S, Tempst P, Ravetch JV. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. of outstanding interest Nature. 383:1996;263-266 Demonstrates that SHIP binds to and is an important mediator of the negative signaling effects of FcγRIIB.
-
(1996)
Nature
, vol.383
, pp. 263-266
-
-
Ono, M.1
Bolland, S.2
Tempst, P.3
Ravetch, J.V.4
-
112
-
-
0028932411
-
Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1
-
D'Ambrosio D, Hippen KH, Minskoff SA, Mellman I, Pani G, Siminovitch KA, Cambier JC. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1. Science. 268:1995;293-297.
-
(1995)
Science
, vol.268
, pp. 293-297
-
-
D'Ambrosio, D.1
Hippen, K.H.2
Minskoff, S.A.3
Mellman, I.4
Pani, G.5
Siminovitch, K.A.6
Cambier, J.C.7
-
113
-
-
0029891083
-
Fc receptor off-signal in the B cell involves apoptosis
-
of special interest. Demonstrates that co-engagement of FcγRIIb with the BCR leads to apoptosis, that is, a negative response rather than just ignorance of the binding as might be expected if the FcR simply blocked BCR signaling events. This suggests that only some BCR signaling events are blocked and that the remaining signals induce apoptosis.
-
Ashman RF, Peckham D, Stunz LL. Fc receptor off-signal in the B cell involves apoptosis. of special interest J Immunol. 157:1996;5-11 Demonstrates that co-engagement of FcγRIIb with the BCR leads to apoptosis, that is, a negative response rather than just ignorance of the binding as might be expected if the FcR simply blocked BCR signaling events. This suggests that only some BCR signaling events are blocked and that the remaining signals induce apoptosis.
-
(1996)
J Immunol
, vol.157
, pp. 5-11
-
-
Ashman, R.F.1
Peckham, D.2
Stunz, L.L.3
-
114
-
-
0031065146
-
Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions
-
of special interest. Demonstrates that FcγRIIB1 inhibits Ras activation by the BCR.
-
Tridandapani S, Chacko GW, Van Brocklyn JR, Coggeshall KM. Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions. of special interest J Immunol. 158:1997;1125-1132 Demonstrates that FcγRIIB1 inhibits Ras activation by the BCR.
-
(1997)
J Immunol
, vol.158
, pp. 1125-1132
-
-
Tridandapani, S.1
Chacko, G.W.2
Van Brocklyn, J.R.3
Coggeshall, K.M.4
-
115
-
-
0028949389
-
Receptor-specific induction of individual AP-1 components in B lymphocytes
-
Huo L, Rothstein TL. Receptor-specific induction of individual AP-1 components in B lymphocytes. J Immunol. 154:1995;3300-3309.
-
(1995)
J Immunol
, vol.154
, pp. 3300-3309
-
-
Huo, L.1
Rothstein, T.L.2
-
116
-
-
0028065085
-
Cell cycle-specific induction of cdk2 expression in B lymphocytes following antigen receptor cross-linking
-
Tanguay D, Chiles T. Cell cycle-specific induction of cdk2 expression in B lymphocytes following antigen receptor cross-linking. Mol Immunol. 31:1994;643-649.
-
(1994)
Mol Immunol
, vol.31
, pp. 643-649
-
-
Tanguay, D.1
Chiles, T.2
-
117
-
-
0030030584
-
PKS-J3/cdk4) for the major D-type cyclin in mature B lymphocytes
-
PKS-J3/cdk4) for the major D-type cyclin in mature B lymphocytes. J Immunol. 156:1996;539-548.
-
(1996)
J Immunol
, vol.156
, pp. 539-548
-
-
Tanguay, D.1
Chiles, T.2
-
118
-
-
10144241685
-
Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes
-
of special interest. This paper examines the expression of important cell cycle regulatory proteins involved in BCR-induced B cell proliferation.
-
Solvason N, Wu W, Kabra N, Wu X, Lees E, Howard M. Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes. of special interest J Exp Med. 184:1996;407-417 This paper examines the expression of important cell cycle regulatory proteins involved in BCR-induced B cell proliferation.
-
(1996)
J Exp Med
, vol.184
, pp. 407-417
-
-
Solvason, N.1
Wu, W.2
Kabra, N.3
Wu, X.4
Lees, E.5
Howard, M.6
-
119
-
-
0030987302
-
Cyclin G2 is upregulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest
-
Horne MC, Donaldson KL, Goolsby GL, Tran D, Mulheisen M, Hell JW, Wahl AF. Cyclin G2 is upregulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest. J Biol Chem. 272:1997;12650-12661.
-
(1997)
J Biol Chem
, vol.272
, pp. 12650-12661
-
-
Horne, M.C.1
Donaldson, K.L.2
Goolsby, G.L.3
Tran, D.4
Mulheisen, M.5
Hell, J.W.6
Wahl, A.F.7
-
120
-
-
0030740148
-
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation
-
in press
-
Chan VWF, Meng F, Soriano P, DeFranco AL, Lowell CA. Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation. Immunity. 7:1997;. in press.
-
(1997)
Immunity
, vol.7
-
-
Chan, V.W.F.1
Meng, F.2
Soriano, P.3
DeFranco, A.L.4
Lowell, C.A.5
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