Structural characteristics of antifolate dihydrofolate reductase enzyme interactions

Crystallography Reviews

Volumn 12, Issue 4, 2006, Pages 301-333

  Cody, Vivian ^a   Schwalbe, Carl H ^b  

^a HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

^b ASTON UNIVERSITY   (United Kingdom)

Author keywords

Active site topology; Conformational flexibility; Dihydrofolate reductase; Protein protein interactions; Ring stacking

Indexed keywords

CATALYST SELECTIVITY; CONFORMATIONS; CRYSTAL STRUCTURE; LIGANDS; PHARMACODYNAMICS;

ACTIVE SITE TOPOLOGY; CONFORMATIONAL FLEXIBILITY; DIHYDROFOLATE REDUCTASE; PROTEIN-PROTEIN INTERACTIONS; RING STACKING;

ENZYMES;

EID: 35948973555     PISSN: 0889311X     EISSN: 14763508     Source Type: Journal    
DOI: 10.1080/08893110701337727     Document Type: Article

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