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Angewandte Chemie - International Edition

Volumn 39, Issue 2, 2000, Pages 290-312

NMR studies of ligand binding to dihydrofolate reductase

(1) Feeney, James a

a NATIONAL INSTITUTE FOR MEDICAL RESEARCH (United Kingdom)

Author keywords

Enzymes; NMR spectroscopy; Protein dynamics; Protein structures; Protein ligand interactions

Indexed keywords

2,4 DIAMINOPYRIMIDINE DERIVATIVE; AMINOPTERIN; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; ENZYME; FOLIC ACID ANTAGONIST; PYRIMETHAMINE; TRIMETHOPRIM;

CHEMICAL STRUCTURE; DRUG DESIGN; ENZYME SUBSTRATE COMPLEX; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN STRUCTURE; REVIEW; STRUCTURE ANALYSIS;

EID: 0034677111 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/(SICI)1521-3773(20000117)39:2<290::AID-ANIE290>3.0.CO;2-1 Document Type: Review

Times cited : (54)

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