Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: Evidence for enolization of pteridine O4

Biochemistry

Volumn 35, Issue 22, 1996, Pages 7012-7020

  Lee, Hyunsook ^a,b   Reyes, Vicente M ^a,c   Kraut, Joseph ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Sangji University   (South Korea)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLINIC ACID;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; ENZYME KINETICS; ENZYME RELEASE; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

4-AMINOBENZOIC ACID; ARGININE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROGEN BONDING; LEUCOVORIN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PTERIDINES; RECOMBINANT PROTEINS; TEMPERATURE; TETRAHYDROFOLATE DEHYDROGENASE;

ESCHERICHIA COLI;

EID: 0029894436     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960028g     Document Type: Article

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