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Volumn 4, Issue 3-4, 2006, Pages 239-256

Oral bioavailability of the flavonol quercetin - A review

Author keywords

Bioavailability; Flavonols; Intestinal absorption; Quercetin3

Indexed keywords

FLAVONOL; GLYCOSYLCERAMIDASE; LACTASE; PHLORIZIN; QUERCETIN;

EID: 34247117650     PISSN: 15407535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (29)

References (101)
  • 1
    • 0035951696 scopus 로고    scopus 로고
    • Interaction of quercetin glucosides with the intestinal sodium/glucose cotransporter (SGLT-1)
    • Ader, P., Blöck, M., Pietzsch, S., Wolffram, S. (2001) Interaction of quercetin glucosides with the intestinal sodium/glucose cotransporter (SGLT-1). Cancer Letters 162, 175-180.
    • (2001) Cancer Letters , vol.162 , pp. 175-180
    • Ader, P.1    Blöck, M.2    Pietzsch, S.3    Wolffram, S.4
  • 2
    • 0034108013 scopus 로고    scopus 로고
    • Bioavailability and metabolism of the flavonol quercetin in the pig
    • Ader, P., Wessmann, A., Wolffram, S. (2000) Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radical Biology & Medicine 28, 1056-1067.
    • (2000) Free Radical Biology & Medicine , vol.28 , pp. 1056-1067
    • Ader, P.1    Wessmann, A.2    Wolffram, S.3
  • 3
    • 0033850592 scopus 로고    scopus 로고
    • Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration
    • Arai, Y., Watanabe, S., Kimira, M., Shimoi, K., Mochizuki, R., Kinae, N. (2000) Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. Journal of Nutrition 130, 2243-2250.
    • (2000) Journal of Nutrition , vol.130 , pp. 2243-2250
    • Arai, Y.1    Watanabe, S.2    Kimira, M.3    Shimoi, K.4    Mochizuki, R.5    Kinae, N.6
  • 4
    • 3142621340 scopus 로고    scopus 로고
    • The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides
    • Arts, I.C.W., Sesink, A.L., Faassen-Peters, M., Hollman, P.C.H. (2004) The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides. British Journal of Nutrition 91, 841-847.
    • (2004) British Journal of Nutrition , vol.91 , pp. 841-847
    • Arts, I.C.W.1    Sesink, A.L.2    Faassen-Peters, M.3    Hollman, P.C.H.4
  • 5
    • 0037467065 scopus 로고    scopus 로고
    • Comparison of the total phenolic and ascorbic acid content of freeze-dried and air-dried marionberry, strawberry, and corn grown using conventional, organic, and sustainable agricultural practices
    • Asami, D.K., Hong, Y.J., Barrett, D.M., Mitchell, A.E. (2003) Comparison of the total phenolic and ascorbic acid content of freeze-dried and air-dried marionberry, strawberry, and corn grown using conventional, organic, and sustainable agricultural practices. Journal of Agricultural and Food Chemistry 51, 1237-1241.
    • (2003) Journal of Agricultural and Food Chemistry , vol.51 , pp. 1237-1241
    • Asami, D.K.1    Hong, Y.J.2    Barrett, D.M.3    Mitchell, A.E.4
  • 7
    • 0037070378 scopus 로고    scopus 로고
    • Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats
    • Auma, K., Ippoushi, K., Ito, H., Higashio, H., Terao, J. (2002) Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats. Journal of Agricultural and Food Chemistry 50, 1706-1712.
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , pp. 1706-1712
    • Auma, K.1    Ippoushi, K.2    Ito, H.3    Higashio, H.4    Terao, J.5
  • 8
    • 2642547799 scopus 로고    scopus 로고
    • Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats
    • Azuma, K., Ippoushi, K., Ito, H., Horie, H., Terao, J. (2003) Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats. Bioscience, Biotechnology, and Biochemistry 67, 2548-2555.
    • (2003) Bioscience, Biotechnology, and Biochemistry , vol.67 , pp. 2548-2555
    • Azuma, K.1    Ippoushi, K.2    Ito, H.3    Horie, H.4    Terao, J.5
  • 10
    • 54749157343 scopus 로고    scopus 로고
    • Flavonols, flavones and anthocyanins as native antioxidants of food and their possible role in the prevention of chronic diseases
    • Böhm, H., Boeing, H., Hempel, J., Raab, B., Kroke, A. (1998) Flavonols, flavones and anthocyanins as native antioxidants of food and their possible role in the prevention of chronic diseases. Zeitschrift für Ernährungswissenschaft 37, 147-163.
    • (1998) Zeitschrift für Ernährungswissenschaft , vol.37 , pp. 147-163
    • Böhm, H.1    Boeing, H.2    Hempel, J.3    Raab, B.4    Kroke, A.5
  • 11
    • 0023548365 scopus 로고
    • Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans
    • Bokkenheuser, V.D., Shackleton, C.H., Winter, J. (1987) Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans. The Biochemical Journal 248, 953-956.
    • (1987) The Biochemical Journal , vol.248 , pp. 953-956
    • Bokkenheuser, V.D.1    Shackleton, C.H.2    Winter, J.3
  • 12
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst, P., Elferink, R.O. (2002) Mammalian ABC transporters in health and disease. Annual Review of Biochemistry 71, 537-592.
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 14
    • 0031721802 scopus 로고    scopus 로고
    • Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
    • Bravo, L. (1998) Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutrition Reviews 56, 317-333.
    • (1998) Nutrition Reviews , vol.56 , pp. 317-333
    • Bravo, L.1
  • 16
    • 0027303188 scopus 로고
    • Genotoxicity of phenolic antioxidants
    • Brusick, D. (1993) Genotoxicity of phenolic antioxidants. Toxicology and Industrial Health 9, 223-230.
    • (1993) Toxicology and Industrial Health , vol.9 , pp. 223-230
    • Brusick, D.1
  • 17
    • 0001048320 scopus 로고
    • Phenolic compounds and their changes in apples during maturation and cold storage
    • Burda, S., Oleszek, W., Lee, C.Y. (1990) Phenolic compounds and their changes in apples during maturation and cold storage. Journal of Agricultural and Food Chemistry 38, 945-948.
    • (1990) Journal of Agricultural and Food Chemistry , vol.38 , pp. 945-948
    • Burda, S.1    Oleszek, W.2    Lee, C.Y.3
  • 18
    • 0002854983 scopus 로고
    • Comparative aspects of detoxication in mammals
    • Ed. WB Jacoby. Academic Press Inc, New York
    • Caldwell, J. (1980) Comparative aspects of detoxication in mammals. In: Enzymatic Basis of Detoxication, pp. 85-114. Ed. WB Jacoby. Academic Press Inc, New York.
    • (1980) Enzymatic Basis of Detoxication , pp. 85-114
    • Caldwell, J.1
  • 19
    • 33645100663 scopus 로고    scopus 로고
    • In vitro degradation of the flavonol quercetin and of quercetin glycosides in the porcine hindgut
    • Cermak, R., Breves, G., Lüpke, M., Wolffram, S. (2006) In vitro degradation of the flavonol quercetin and of quercetin glycosides in the porcine hindgut. Archives of Animal Nutrition 60, 180-189.
    • (2006) Archives of Animal Nutrition , vol.60 , pp. 180-189
    • Cermak, R.1    Breves, G.2    Lüpke, M.3    Wolffram, S.4
  • 20
    • 0042419922 scopus 로고    scopus 로고
    • The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors
    • Cermak, R., Landgraf, S., Wolffram, S. (2003) The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors. Journal of Nutrition 133, 2802-2807.
    • (2003) Journal of Nutrition , vol.133 , pp. 2802-2807
    • Cermak, R.1    Landgraf, S.2    Wolffram, S.3
  • 21
    • 3142549141 scopus 로고    scopus 로고
    • Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum
    • Cermak, R., Landgraf, S., Wolffram, S. (2004) Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum. British Journal of Nutrition 91, 849-855.
    • (2004) British Journal of Nutrition , vol.91 , pp. 849-855
    • Cermak, R.1    Landgraf, S.2    Wolffram, S.3
  • 22
    • 0030614844 scopus 로고    scopus 로고
    • Physiochemical and physiological mechanisms for the effects of food on drug absorption: The role of lipids and pH
    • Charman, W.N., Porter, C.J., Mithani, S., Dressman, J.B. (1997) Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH. Journal of Pharmaceutical Sciences 86, 269-282.
    • (1997) Journal of Pharmaceutical Sciences , vol.86 , pp. 269-282
    • Charman, W.N.1    Porter, C.J.2    Mithani, S.3    Dressman, J.B.4
  • 23
    • 34247126182 scopus 로고    scopus 로고
    • Karg, G. (2004) Ernährungssituation in Deutschland. In: Ernährungsbericht 2004, pp. 21-115. Ed. Deutsche Gesellschaft für Ernährung e.V. (DGE). Medienhaus Plump, Rheinbreitbach.
    • Karg, G. (2004) Ernährungssituation in Deutschland. In: Ernährungsbericht 2004, pp. 21-115. Ed. Deutsche Gesellschaft für Ernährung e.V. (DGE). Medienhaus Plump, Rheinbreitbach.
  • 24
    • 0030068760 scopus 로고    scopus 로고
    • Flavonoid intake and coronary mortality in Finland: A cohort study
    • Knekt, P., Jarvinen, R., Reunanen, A., Maatela, J. (1996) Flavonoid intake and coronary mortality in Finland: a cohort study. British Medical Journal 312, 478-481.
    • (1996) British Medical Journal , vol.312 , pp. 478-481
    • Knekt, P.1    Jarvinen, R.2    Reunanen, A.3    Maatela, J.4
  • 25
    • 0242434131 scopus 로고    scopus 로고
    • Changes induced in properties of food proteins by apigenin and quercetin
    • Kroll, J., Rawel, H.M., Czajka, D. (2002) Changes induced in properties of food proteins by apigenin and quercetin. Food Science and Biotechnology 11, 1-3.
    • (2002) Food Science and Biotechnology , vol.11 , pp. 1-3
    • Kroll, J.1    Rawel, H.M.2    Czajka, D.3
  • 26
    • 0016906546 scopus 로고
    • The flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kühnau, J. (1976) The flavonoids. A class of semi-essential food components: their role in human nutrition. World Review of Nutrition and Dietetics 24, 117-191.
    • (1976) World Review of Nutrition and Dietetics , vol.24 , pp. 117-191
    • Kühnau, J.1
  • 28
    • 2642574313 scopus 로고    scopus 로고
    • Bioavailability of quercetin in pigs is influenced by the dietary fat content
    • Lesser, S., Cermak, R., Wolffram, S. (2004) Bioavailability of quercetin in pigs is influenced by the dietary fat content. Journal of Nutrition 134, 1508-1511.
    • (2004) Journal of Nutrition , vol.134 , pp. 1508-1511
    • Lesser, S.1    Cermak, R.2    Wolffram, S.3
  • 29
    • 0031471298 scopus 로고    scopus 로고
    • Flavonoid intake of adults in a Bavarian subgroup of the national food consumption survey
    • Linseisen, J., Radtke J., Wolfram, G. (1997) Flavonoid intake of adults in a Bavarian subgroup of the national food consumption survey. Zeitschrift für Ernährungswissenschaft 36, 403-412.
    • (1997) Zeitschrift für Ernährungswissenschaft , vol.36 , pp. 403-412
    • Linseisen, J.1    Radtke, J.2    Wolfram, G.3
  • 30
    • 0032562766 scopus 로고    scopus 로고
    • Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
    • Manach, C., Morand, C., Crespy, V., Demigné, C., Texier, O., Régérat, F., Rémésy, C. (1998) Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties. FEBS Letters 426, 331-336.
    • (1998) FEBS Letters , vol.426 , pp. 331-336
    • Manach, C.1    Morand, C.2    Crespy, V.3    Demigné, C.4    Texier, O.5    Régérat, F.6    Rémésy, C.7
  • 37
    • 0031436636 scopus 로고    scopus 로고
    • Cytosolic pyridoxine-beta-D-glucoside hydrolase from porcine jejunal mucosa. Purification, properties, and comparison with broad specificity beta-glucosidase
    • McMahon, L.G., Nakano, H., Levy, M.D., Gregory, J.F. III (1997) Cytosolic pyridoxine-beta-D-glucoside hydrolase from porcine jejunal mucosa. Purification, properties, and comparison with broad specificity beta-glucosidase. The Journal of Biological Chemistry 272, 32025-32033.
    • (1997) The Journal of Biological Chemistry , vol.272 , pp. 32025-32033
    • McMahon, L.G.1    Nakano, H.2    Levy, M.D.3    Gregory III, J.F.4
  • 38
    • 0029742815 scopus 로고    scopus 로고
    • Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs
    • Merfort, I., Heilmann, J., Weiss, M., Pietra, P., Gardana, C. (1996) Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs. Planta medica 62, 289-292.
    • (1996) Planta medica , vol.62 , pp. 289-292
    • Merfort, I.1    Heilmann, J.2    Weiss, M.3    Pietra, P.4    Gardana, C.5
  • 40
    • 0034491103 scopus 로고    scopus 로고
    • Quercetin 3-O-beta-glucoside is better absorbed than other quercetin forms and is not present in rat plasma
    • Morand, C., Manach, C., Crespy, V., Rémésy, C. (2000a) Quercetin 3-O-beta-glucoside is better absorbed than other quercetin forms and is not present in rat plasma. Free Radical Research 33, 667-676.
    • (2000) Free Radical Research , vol.33 , pp. 667-676
    • Morand, C.1    Manach, C.2    Crespy, V.3    Rémésy, C.4
  • 41
    • 0034494884 scopus 로고    scopus 로고
    • Respective bioavailability of quercetin aglycone and its glycosides in a rat model
    • Morand, C., Manach, C., Crespy, V., Rémésy, C. (2000b) Respective bioavailability of quercetin aglycone and its glycosides in a rat model. Biofactors 12, 169-174.
    • (2000) Biofactors , vol.12 , pp. 169-174
    • Morand, C.1    Manach, C.2    Crespy, V.3    Rémésy, C.4
  • 42
    • 0034665067 scopus 로고    scopus 로고
    • Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers
    • Movileanu, L., Neagoe, I., Flonta, M.L. (2000) Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers. International Journal of Pharmaceutics 205, 135-146.
    • (2000) International Journal of Pharmaceutics , vol.205 , pp. 135-146
    • Movileanu, L.1    Neagoe, I.2    Flonta, M.L.3
  • 43
    • 8444233189 scopus 로고    scopus 로고
    • Flavonoid metabolites in human plasma and urine after the consumption of red onions: Analysis by liquid chromatography with photodiode array and full scan tandem mass spectrometric detection
    • Mullen, W., Boitier, A., Stewart, A.J., Crozier, A. (2004) Flavonoid metabolites in human plasma and urine after the consumption of red onions: analysis by liquid chromatography with photodiode array and full scan tandem mass spectrometric detection. Journal of Chromatography A 1058, 163-168.
    • (2004) Journal of Chromatography A , vol.1058 , pp. 163-168
    • Mullen, W.1    Boitier, A.2    Stewart, A.J.3    Crozier, A.4
  • 44
    • 0037032253 scopus 로고    scopus 로고
    • Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4′-glucoside
    • Mullen, W., Graf, B.A., Caldwell, S.T., Hartley, R.C., Duthie, G.G., Edwards, C.A., Lean, M.E., Crozier, A. (2002) Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4′-glucoside. Journal of Agricultural and Food Chemistry 50, 6902-6909.
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , pp. 6902-6909
    • Mullen, W.1    Graf, B.A.2    Caldwell, S.T.3    Hartley, R.C.4    Duthie, G.G.5    Edwards, C.A.6    Lean, M.E.7    Crozier, A.8
  • 45
    • 25844526542 scopus 로고    scopus 로고
    • Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach
    • Murota, K., Terao, J. (2005) Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach. FEBS Letters 579, 5343-5346.
    • (2005) FEBS Letters , vol.579 , pp. 5343-5346
    • Murota, K.1    Terao, J.2
  • 46
    • 0037219688 scopus 로고    scopus 로고
    • Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans
    • Németh, K., Plumb, G.W., Berrin J.G., Juge, N., Jacob, R., Naim, H.Y., Williamson, G., Swallow, D.M., Kroon, P.A. (2003) Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. European Journal of Nutrition 42, 29-42.
    • (2003) European Journal of Nutrition , vol.42 , pp. 29-42
    • Németh, K.1    Plumb, G.W.2    Berrin, J.G.3    Juge, N.4    Jacob, R.5    Naim, H.Y.6    Williamson, G.7    Swallow, D.M.8    Kroon, P.A.9
  • 47
    • 0037300834 scopus 로고    scopus 로고
    • Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: The role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism
    • O'Leary, K.A., Day, A.J., Needs, P.W., Mellon, F.A., O'Brien, N.M., Williamson, G. (2003) Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochemical Pharmacology 65, 479-491.
    • (2003) Biochemical Pharmacology , vol.65 , pp. 479-491
    • O'Leary, K.A.1    Day, A.J.2    Needs, P.W.3    Mellon, F.A.4    O'Brien, N.M.5    Williamson, G.6
  • 50
    • 0034054933 scopus 로고    scopus 로고
    • Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans
    • Olthof, M.R., Hollman, P.C.H., Vree, T.B., Katan, M.B. (2000) Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans. Journal of Nutrition 130, 1200-1203.
    • (2000) Journal of Nutrition , vol.130 , pp. 1200-1203
    • Olthof, M.R.1    Hollman, P.C.H.2    Vree, T.B.3    Katan, M.B.4
  • 51
    • 0034812454 scopus 로고    scopus 로고
    • Sulfation of flavonoids and other phenolic dietary compounds by the human cytosolic sulfotransferases
    • Pai, T.G., Suiko, M., Sakakibara, Y., Liu, M.C. (2001) Sulfation of flavonoids and other phenolic dietary compounds by the human cytosolic sulfotransferases. Biochemical and Biophysical Research Communications 285, 1175-1179.
    • (2001) Biochemical and Biophysical Research Communications , vol.285 , pp. 1175-1179
    • Pai, T.G.1    Suiko, M.2    Sakakibara, Y.3    Liu, M.C.4
  • 52
    • 0020683275 scopus 로고
    • Activation of rutin by human oral bacterial isolates to the carcinogen-mutagen quercetin
    • Parisis, D.M., Pritchard, E.T. (1983) Activation of rutin by human oral bacterial isolates to the carcinogen-mutagen quercetin. Archives of Oral Biology 28, 583-590.
    • (1983) Archives of Oral Biology , vol.28 , pp. 583-590
    • Parisis, D.M.1    Pritchard, E.T.2
  • 53
    • 0037518134 scopus 로고    scopus 로고
    • Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo
    • Petri, N., Tannergren, C., Hoist, B., et al. (2003) Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo. Drug Metabolism and Disposition 31, 805-813.
    • (2003) Drug Metabolism and Disposition , vol.31 , pp. 805-813
    • Petri, N.1    Tannergren, C.2    Hoist, B.3
  • 54
    • 34247132303 scopus 로고    scopus 로고
    • Favonoids in herbs
    • Eds. C. Rice-Evans and L. Packer. Marcel Dekker Inc, New York
    • Piena, P., Gardana, C., Pietta, A. (2003) Favonoids in herbs. In: Flavonoids in health and disease, pp. 43-69. Eds. C. Rice-Evans and L. Packer. Marcel Dekker Inc, New York.
    • (2003) Flavonoids in health and disease , pp. 43-69
    • Piena, P.1    Gardana, C.2    Pietta, A.3
  • 56
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta, P.G. (2000) Flavonoids as antioxidants. Journal of Natural Products 63, 1035-1042.
    • (2000) Journal of Natural Products , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 58
    • 0034495112 scopus 로고    scopus 로고
    • Factors affecting flavonoids absorption
    • Piskula, M.K. (2000) Factors affecting flavonoids absorption. Biofactors 12, 175-180.
    • (2000) Biofactors , vol.12 , pp. 175-180
    • Piskula, M.K.1
  • 59
    • 0031820964 scopus 로고    scopus 로고
    • Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues
    • Piskula, M.K., Terao, J. (1998a) Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues. Journal of Nutrition 128, 1172-1178.
    • (1998) Journal of Nutrition , vol.128 , pp. 1172-1178
    • Piskula, M.K.1    Terao, J.2
  • 60
    • 0000756228 scopus 로고    scopus 로고
    • Quercetin's solubility affects its accumulation in rat plasma after oral administration
    • Piskula, M.K., Terao, J. (1998b) Quercetin's solubility affects its accumulation in rat plasma after oral administration. Journal of Agricultural and Food Chemistry 46, 4313-4317.
    • (1998) Journal of Agricultural and Food Chemistry , vol.46 , pp. 4313-4317
    • Piskula, M.K.1    Terao, J.2
  • 61
    • 0031669994 scopus 로고    scopus 로고
    • Composition and content of flavonol glycosides in broccoli florets (Brassica olearancea) and their fate during cooking
    • Price, K.R., Casuscelli, F., Colquhoun, I.J., Rhodes, M.J.C. (1997) Composition and content of flavonol glycosides in broccoli florets (Brassica olearancea) and their fate during cooking. Journal of the Science of Food and Agriculture 77, 468-472.
    • (1997) Journal of the Science of Food and Agriculture , vol.77 , pp. 468-472
    • Price, K.R.1    Casuscelli, F.2    Colquhoun, I.J.3    Rhodes, M.J.C.4
  • 62
    • 0030856966 scopus 로고    scopus 로고
    • Analysis of the major flavonol glycosides present in four varieties of onion (Allium cepa) and changes in composition resulting from autolysis
    • Price, K.R., Rhodes, M.J.C. (1997) Analysis of the major flavonol glycosides present in four varieties of onion (Allium cepa) and changes in composition resulting from autolysis. Journal of the Science of Food and Agriculture 74, 331-339.
    • (1997) Journal of the Science of Food and Agriculture , vol.74 , pp. 331-339
    • Price, K.R.1    Rhodes, M.J.C.2
  • 66
    • 0029888128 scopus 로고    scopus 로고
    • Structure-antioxidant activity relationships of flavonoids and phenolic acids
    • Rice-Evans, C.A., Miller, N.J., Faganga, G. (1996) Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology & Medicine 20, 933-956.
    • (1996) Free Radical Biology & Medicine , vol.20 , pp. 933-956
    • Rice-Evans, C.A.1    Miller, N.J.2    Faganga, G.3
  • 67
    • 0030240388 scopus 로고    scopus 로고
    • Relation between intake of flavonoids and risk for coronary heart disease in male health professionals
    • Rimm, E.B., Katan, M.B., Acherio, A., Stampfer, M.J., Willett, W.C. (1996) Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Annals of Internal Medicine 125, 384-389.
    • (1996) Annals of Internal Medicine , vol.125 , pp. 384-389
    • Rimm, E.B.1    Katan, M.B.2    Acherio, A.3    Stampfer, M.J.4    Willett, W.C.5
  • 68
    • 0000131714 scopus 로고
    • Die Gehalte an Hydroxyzimtsäure- Verbindungen und Catechinen in Kern- und Steinobst
    • Risch, B., Herrmann, K. (1988) Die Gehalte an Hydroxyzimtsäure- Verbindungen und Catechinen in Kern- und Steinobst. Zeitschrift für Lebensmittel-Untersuchung und-Forschung 186, 225-230.
    • (1988) Zeitschrift für Lebensmittel-Untersuchung und-Forschung , vol.186 , pp. 225-230
    • Risch, B.1    Herrmann, K.2
  • 69
    • 20744444385 scopus 로고    scopus 로고
    • Experimental determination of octanol-water partition coefficients of quercetin and related flavonoids
    • Rothwell, J.A., Day, A.J., Morgan, M.R.A. (2005) Experimental determination of octanol-water partition coefficients of quercetin and related flavonoids. Journal of Agricultural and Food Chemistry 53, 4355-4360.
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , pp. 4355-4360
    • Rothwell, J.A.1    Day, A.J.2    Morgan, M.R.A.3
  • 72
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Scalbert, A., Williamson, G. (2000) Dietary intake and bioavailability of polyphenols. Journal of Nutrition 130, 2073S-2085S.
    • (2000) Journal of Nutrition , vol.130
    • Scalbert, A.1    Williamson, G.2
  • 76
    • 0344806276 scopus 로고    scopus 로고
    • Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: Description of quantitative structure-activity relationships
    • Sergedienë, E., Jönsson, K., Szymusiak, H., Tyrakowska, B., Rietjens, I.M.C.M., Èënas, N. (1999) Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationships. FEBS Letters 462, 392-396.
    • (1999) FEBS Letters , vol.462 , pp. 392-396
    • Sergedienë, E.1    Jönsson, K.2    Szymusiak, H.3    Tyrakowska, B.4    Rietjens, I.M.C.M.5    Èënas, N.6
  • 77
    • 21744461919 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides
    • Sesink, A.L., Arts, I.C.W., de Boer, V.C., Breedveld, P., Schellens, J.H., Hollman, P.C.H., Russel, F.G. (2005) Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Molecular Pharmacology 67, 1999-2006.
    • (2005) Molecular Pharmacology , vol.67 , pp. 1999-2006
    • Sesink, A.L.1    Arts, I.C.W.2    de Boer, V.C.3    Breedveld, P.4    Schellens, J.H.5    Hollman, P.C.H.6    Russel, F.G.7
  • 78
    • 0037373381 scopus 로고    scopus 로고
    • Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase phlorizin hydrolase
    • Sesink, A.L., Arts, I.C.W., Faassen-Peters, M., Hollman, P.C.H. (2003) Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase phlorizin hydrolase. Journal of Nutrition 133, 773-776.
    • (2003) Journal of Nutrition , vol.133 , pp. 773-776
    • Sesink, A.L.1    Arts, I.C.W.2    Faassen-Peters, M.3    Hollman, P.C.H.4
  • 79
    • 0036898114 scopus 로고    scopus 로고
    • The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones
    • Setchell, K.D.R., Brown, N.M., Lydeking-Olsen, E. (2002) The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones. Journal of Nutrition 132, 3577-3584.
    • (2002) Journal of Nutrition , vol.132 , pp. 3577-3584
    • Setchell, K.D.R.1    Brown, N.M.2    Lydeking-Olsen, E.3
  • 81
    • 1542578194 scopus 로고    scopus 로고
    • Metabolism in the small intestine and gastrointestinal tract
    • Eds. C. Rice-Evans and L. Packer. Marcel Dekker Inc, New York
    • Spencer, J.P.E., Rice-Evans, C.A. (2003) Metabolism in the small intestine and gastrointestinal tract. In: Flavonoids in Health and Disease, pp. 363-389. Eds. C. Rice-Evans and L. Packer. Marcel Dekker Inc, New York.
    • (2003) Flavonoids in Health and Disease , pp. 363-389
    • Spencer, J.P.E.1    Rice-Evans, C.A.2
  • 85
    • 0033847137 scopus 로고    scopus 로고
    • Efflux of dietary flavonoid quercetin 4′-beta-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2
    • Walgren, R.A., Karnaky, K.J. Jr., Lindenmayer, G.E., Walle, T. (2000a) Efflux of dietary flavonoid quercetin 4′-beta-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2. The Journal of Pharmacohgy and Experimental Therapeutics 294, 830-836.
    • (2000) The Journal of Pharmacohgy and Experimental Therapeutics , vol.294 , pp. 830-836
    • Walgren, R.A.1    Karnaky Jr., K.J.2    Lindenmayer, G.E.3    Walle, T.4
  • 86
    • 0033846534 scopus 로고    scopus 로고
    • Cellular uptake of dietary flavonoid quercetin 4′-beta-glucoside by sodium-dependent glucose transporter SGLT1
    • Walgren, R.A., Lin, J.T., Kinne, R.K., Walle, T. (2000b) Cellular uptake of dietary flavonoid quercetin 4′-beta-glucoside by sodium-dependent glucose transporter SGLT1. The Journal of Pharmacohgy and Experimental Therapeutics 294, 837-843.
    • (2000) The Journal of Pharmacohgy and Experimental Therapeutics , vol.294 , pp. 837-843
    • Walgren, R.A.1    Lin, J.T.2    Kinne, R.K.3    Walle, T.4
  • 87
    • 0032524982 scopus 로고    scopus 로고
    • Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells
    • Walgren, R.A., Walle, U.K., Walle, T. (1998) Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells. Biochemical Pharmacohgy 55, 1721-1727.
    • (1998) Biochemical Pharmacohgy , vol.55 , pp. 1721-1727
    • Walgren, R.A.1    Walle, U.K.2    Walle, T.3
  • 88
    • 11844269306 scopus 로고    scopus 로고
    • Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans
    • Walle, T., Browning, A.M., Steed, L.L., Reed, S.G., Walle, U.K. (2005) Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans. Journal of Nutrition 135, 48-52.
    • (2005) Journal of Nutrition , vol.135 , pp. 48-52
    • Walle, T.1    Browning, A.M.2    Steed, L.L.3    Reed, S.G.4    Walle, U.K.5
  • 89
    • 0033735623 scopus 로고    scopus 로고
    • Quercetin glucosides are completely hydrolyzed in ileostomy patients before absorption
    • Walle, T., Otake, Y., Walle, U.K., Wilson, F.A. (2000) Quercetin glucosides are completely hydrolyzed in ileostomy patients before absorption. Journal of Nutrition 130, 2658-2661.
    • (2000) Journal of Nutrition , vol.130 , pp. 2658-2661
    • Walle, T.1    Otake, Y.2    Walle, U.K.3    Wilson, F.A.4
  • 90
    • 0034795649 scopus 로고    scopus 로고
    • Carbon dioxide is the major metabolite of quercetin in humans
    • Walle, T., Walle, U.K., Halushka, P.V. (2001) Carbon dioxide is the major metabolite of quercetin in humans. Journal of Nutrition 131, 2648-2652.
    • (2001) Journal of Nutrition , vol.131 , pp. 2648-2652
    • Walle, T.1    Walle, U.K.2    Halushka, P.V.3
  • 91
    • 0141625125 scopus 로고    scopus 로고
    • Disposition of quercetin and kaempferol in human following an oral administration of Ginkgo biloba exttact tablets
    • Wang, F.M., Yao, T.W., Zeng, S. (2003) Disposition of quercetin and kaempferol in human following an oral administration of Ginkgo biloba exttact tablets. European Journal of Drug Metabolism and Pharmacokinetics 28, 173-177.
    • (2003) European Journal of Drug Metabolism and Pharmacokinetics , vol.28 , pp. 173-177
    • Wang, F.M.1    Yao, T.W.2    Zeng, S.3
  • 92
    • 18844425527 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: Quercetin, kaempferol, and isorhamnetin
    • Wang, Y., Cao, J., Zeng, S. (2005) Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. The Journal of Pharmacy and Pharmacohgy 57, 751-758.
    • (2005) The Journal of Pharmacy and Pharmacohgy , vol.57 , pp. 751-758
    • Wang, Y.1    Cao, J.2    Zeng, S.3
  • 93
    • 21544451970 scopus 로고    scopus 로고
    • Food safety and epidemiology: New database of functional food factors
    • Watanabe, S., Zhuo, X.G., Kimira, M. (2004) Food safety and epidemiology: new database of functional food factors. Biofactors 22, 213-219.
    • (2004) Biofactors , vol.22 , pp. 213-219
    • Watanabe, S.1    Zhuo, X.G.2    Kimira, M.3
  • 94
    • 0346362338 scopus 로고    scopus 로고
    • Quercetin, an over-the-counter supplement, causes neuroblastoma-like elevation of plasma homovanillic acid
    • Weldin, J. Jack, R., Dugaw, K., Kapur, R.P. (2003) Quercetin, an over-the-counter supplement, causes neuroblastoma-like elevation of plasma homovanillic acid. Pediatric and Developmental Pathology 6, 547-551.
    • (2003) Pediatric and Developmental Pathology , vol.6 , pp. 547-551
    • Weldin, J.1    Jack, R.2    Dugaw, K.3    Kapur, R.P.4
  • 96
    • 9344267252 scopus 로고    scopus 로고
    • Williams, C.A., Harborne, J.B. (1994) Flavone and flavonol glycosides. In: The Flavonoids: Advances in Research since 1986, pp. 337-385. Ed. J.B. Harborne. Chapman & Hall, London.
    • Williams, C.A., Harborne, J.B. (1994) Flavone and flavonol glycosides. In: The Flavonoids: Advances in Research since 1986, pp. 337-385. Ed. J.B. Harborne. Chapman & Hall, London.
  • 98
    • 0036213863 scopus 로고    scopus 로고
    • Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine
    • Wolffram, S., Blöck, M., Ader, P. (2002) Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine. Journal of Nutrition 132, 630-635.
    • (2002) Journal of Nutrition , vol.132 , pp. 630-635
    • Wolffram, S.1    Blöck, M.2    Ader, P.3
  • 101
    • 0037300833 scopus 로고    scopus 로고
    • Probing the binding of the flavonoid, quercetin to human serum albumin by circular dichroism, electronic absorption spectroscopy and molecular modelling methods
    • Zsila, F., Bikadi, Z., Simonyi, M. (2003) Probing the binding of the flavonoid, quercetin to human serum albumin by circular dichroism, electronic absorption spectroscopy and molecular modelling methods. Biochemical Pharmacology 65, 447-456.
    • (2003) Biochemical Pharmacology , vol.65 , pp. 447-456
    • Zsila, F.1    Bikadi, Z.2    Simonyi, M.3


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