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Volumn 55, Issue 10, 1998, Pages 1721-1727

Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells

Author keywords

Apparent permeability; Bioflavonoids; Caco 2 cells; Glucosides; Intestinal absorption; Quercetin

Indexed keywords

MANNITOL; PROPRANOLOL; QUERCETIN; QUERCETIN 3,4 DIGLUCOSIDE; QUERCETIN 4 GLUCOSIDE; UNCLASSIFIED DRUG;

EID: 0032524982     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00048-3     Document Type: Article
Times cited : (236)

References (39)
  • 1
    • 33751391867 scopus 로고
    • Content of potentially anticarcinogenic flavonoids of 28 vege tables and 9 fruits commonly consumed in the Netherlands
    • Hertog MGL, Hollman PCH, Katan MB. Content of potentially anticarcinogenic flavonoids of 28 vege tables and 9 fruits commonly consumed in the Netherlands. J Agric Food Chem. 40:1992;2379-2383.
    • (1992) J Agric Food Chem , vol.40 , pp. 2379-2383
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Katan, M.B.3
  • 2
    • 0347197907 scopus 로고
    • Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices
    • Hertog MGL, Hollman PCH, van de Putte B. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices. J Agric Food Chem. 41:1993;1242-1246.
    • (1993) J Agric Food Chem , vol.41 , pp. 1242-1246
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Van De Putte, B.3
  • 4
    • 0030068760 scopus 로고    scopus 로고
    • Flavonoid intake and coronary mortality in Finland: A cohort study
    • Knekt P, Järvinen R, Reunanen A, Maatela J. Flavonoid intake and coronary mortality in Finland A cohort study . Br Med J. 312:1996;478-481.
    • (1996) Br Med J , vol.312 , pp. 478-481
    • Knekt, P.1    Järvinen, R.2    Reunanen, A.3    Maatela, J.4
  • 5
    • 0029868401 scopus 로고    scopus 로고
    • Dietary flavonoids, antioxidant vitamins, and incidence of stroke: The Zutphen study
    • Keli SO, Hertog MGL, Feskens EJM, Kromhout D. Dietary flavonoids, antioxidant vitamins, and incidence of stroke The Zutphen study . Arch Intern Med. 156:1996;637-642.
    • (1996) Arch Intern Med , vol.156 , pp. 637-642
    • Keli, S.O.1    Hertog, M.G.L.2    Feskens, E.J.M.3    Kromhout, D.4
  • 6
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources
    • Cook NC, Samman S. Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources. J Nutr Biochem. 7:1996;66-76.
    • (1996) J Nutr Biochem , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2
  • 7
    • 0029065391 scopus 로고
    • The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
    • Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis Implications for protection against coronary heart disease . Clin Chim Acta. 235:1995;207-219.
    • (1995) Clin Chim Acta , vol.235 , pp. 207-219
    • Pace-Asciak, C.R.1    Hahn, S.2    Diamandis, E.P.3    Soleas, G.4    Goldberg, D.M.5
  • 8
    • 0030051539 scopus 로고    scopus 로고
    • Interactions of flavonoids and other phytochemicals with adenosine receptors
    • Ji X, Melman N, Jacobson KA. Interactions of flavonoids and other phytochemicals with adenosine receptors. J Med Chem. 39:1996;781-788.
    • (1996) J Med Chem , vol.39 , pp. 781-788
    • Ji, X.1    Melman, N.2    Jacobson, K.A.3
  • 9
    • 0025885064 scopus 로고
    • Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
    • Deschner EE, Ruperto J, Wong G, Newark HL. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis. 12:1991;1193-1196.
    • (1991) Carcinogenesis , vol.12 , pp. 1193-1196
    • Deschner, E.E.1    Ruperto, J.2    Wong, G.3    Newark, H.L.4
  • 10
    • 0027485394 scopus 로고
    • The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet
    • Deschner EE, Ruperto JF, Wong GY, Newmark HL. The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet. Nutr Cancer. 20:1993;199-204.
    • (1993) Nutr Cancer , vol.20 , pp. 199-204
    • Deschner, E.E.1    Ruperto, J.F.2    Wong, G.Y.3    Newmark, H.L.4
  • 12
    • 0028360527 scopus 로고
    • Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice
    • Wang ZY, Huang M-T, Lou Y-R, Xie J-G, Reuhl KR, Newmark HL, Ho C-T, Yang CS, Conney AH. Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice. Cancer Res. 54:1994;3428-3435.
    • (1994) Cancer Res , vol.54 , pp. 3428-3435
    • Wang, Z.Y.1    Huang M-T2    Lou Y-R3    Xie J-G4    Reuhl, K.R.5    Newmark, H.L.6    Ho C-T7    Yang, C.S.8    Conney, A.H.9
  • 14
    • 0030796989 scopus 로고    scopus 로고
    • 1 cell-cycle arrest by the chemopreventive agent apigenin
    • 1 cell-cycle arrest by the chemopreventive agent apigenin. Mol Carcinog. 19:1997;74-82.
    • (1997) Mol Carcinog , vol.19 , pp. 74-82
    • Lepley, D.M.1    Pelling, J.C.2
  • 16
    • 0028268359 scopus 로고
    • Isoenzyme- And species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids
    • Tsyrlov IB, Mikhailenko VM, Gelboin HV. Isoenzyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids. Biochim Biophys Acta. 1205:1994;325-335.
    • (1994) Biochim Biophys Acta , vol.1205 , pp. 325-335
    • Tsyrlov, I.B.1    Mikhailenko, V.M.2    Gelboin, H.V.3
  • 17
    • 0029092127 scopus 로고
    • Quercetin, a potent and specific inhibitor of the human P-form phenolsulfotransferase
    • Walle T, Eaton EA, Walle UK. Quercetin, a potent and specific inhibitor of the human P-form phenolsulfotransferase. Biochem Pharmacol. 50:1995;731-734.
    • (1995) Biochem Pharmacol , vol.50 , pp. 731-734
    • Walle, T.1    Eaton, E.A.2    Walle, U.K.3
  • 18
    • 0016811010 scopus 로고
    • Disposition of quercetin in man after single oral and intravenous doses
    • Gugler R, Leschik M, Dengler HJ. Disposition of quercetin in man after single oral and intravenous doses. Eur J Clin Pharmacol. 9:1975;229-234.
    • (1975) Eur J Clin Pharmacol , vol.9 , pp. 229-234
    • Gugler, R.1    Leschik, M.2    Dengler, H.J.3
  • 21
    • 0023548365 scopus 로고
    • Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans
    • Bokkenheuser VD, Shackleton CHL, Winter J. Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans. Biochem J. 248:1987;953-956.
    • (1987) Biochem J , vol.248 , pp. 953-956
    • Bokkenheuser, V.D.1    Shackleton, C.H.L.2    Winter, J.3
  • 23
    • 0025311288 scopus 로고
    • Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorbtive (Caco-2) cells
    • Artursson P. Epithelial transport of drugs in cell culture. I A model for studying the passive diffusion of drugs over intestinal absorbtive (Caco-2) cells . J Pharm Sci. 79:1990;476-482.
    • (1990) J Pharm Sci , vol.79 , pp. 476-482
    • Artursson, P.1
  • 24
    • 0027180795 scopus 로고
    • Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers
    • Hunter J, Hirst BH, Simmons NL. Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers. Pharm Res. 10:1993;743-749.
    • (1993) Pharm Res , vol.10 , pp. 743-749
    • Hunter, J.1    Hirst, B.H.2    Simmons, N.L.3
  • 25
    • 0028786481 scopus 로고
    • The human intestinal epithelial cell line Caco-2; Pharmacological and pharmacokinetic applications
    • Meunier V, Bourrié M, Berger Y, Fabre G. The human intestinal epithelial cell line Caco-2; Pharmacological and pharmacokinetic applications. Cell Biol Toxicol. 11:1995;187-194.
    • (1995) Cell Biol Toxicol , vol.11 , pp. 187-194
    • Meunier, V.1    Bourrié, M.2    Berger, Y.3    Fabre, G.4
  • 26
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P, Karlsson J. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun. 175:1991;880-885.
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 27
    • 0030797273 scopus 로고    scopus 로고
    • Human jejunal effective permeability and its correlation with preclinical drug absorption models
    • Lennernäs H. Human jejunal effective permeability and its correlation with preclinical drug absorption models. J Pharm Pharmacol. 49:1997;627-638.
    • (1997) J Pharm Pharmacol , vol.49 , pp. 627-638
    • Lennernäs, H.1
  • 28
    • 0030856966 scopus 로고    scopus 로고
    • Analysis of the major flavonol glycosides present in four varieties of onion (Allium cepa) and changes in composition resulting from autolysis
    • Price KR, Rhodes MJC. Analysis of the major flavonol glycosides present in four varieties of onion (Allium cepa) and changes in composition resulting from autolysis. J Sci Food Agric. 74:1997;331-339.
    • (1997) J Sci Food Agric , vol.74 , pp. 331-339
    • Price, K.R.1    Rhodes, M.J.C.2
  • 29
    • 0025732815 scopus 로고
    • A model of human small intestinal absorptive cells. 1. Transport barrier
    • Cogbum JN, Donovan MG, Schasteen CS. A model of human small intestinal absorptive cells. 1. Transport barrier. Pharm Res. 8:1991;210-216.
    • (1991) Pharm Res , vol.8 , pp. 210-216
    • Cogbum, J.N.1    Donovan, M.G.2    Schasteen, C.S.3
  • 30
    • 0029927801 scopus 로고    scopus 로고
    • Transport properties are not altered across Caco-2 cells with heightened TEER despite underlying physiological and ultrastructural changes
    • Lu S, Gough AW, Bobrowski WF, Stewart BH. Transport properties are not altered across Caco-2 cells with heightened TEER despite underlying physiological and ultrastructural changes. J Pharm Sci. 85:1996;270-273.
    • (1996) J Pharm Sci , vol.85 , pp. 270-273
    • Lu, S.1    Gough, A.W.2    Bobrowski, W.F.3    Stewart, B.H.4
  • 31
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study
    • Hertog MGL, Feskens EJM, Holiman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease The Zutphen Elderly Study . Lancet. 342:1993;1007-1011.
    • (1993) Lancet , vol.342 , pp. 1007-1011
    • Hertog, M.G.L.1    Feskens, E.J.M.2    Holiman, P.C.H.3    Katan, M.B.4    Kromhout, D.5
  • 32
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro AB, Ling V. Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol. 53:1997;587-596.
    • (1997) Biochem Pharmacol , vol.53 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 33
    • 0027181852 scopus 로고
    • Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators
    • Hunter J, Jepson MA, Tsuruo T, Simmons NL, Hirst BH. Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators. J Biol Chem. 268:1993;14991-14997.
    • (1993) J Biol Chem , vol.268 , pp. 14991-14997
    • Hunter, J.1    Jepson, M.A.2    Tsuruo, T.3    Simmons, N.L.4    Hirst, B.H.5
  • 34
    • 0030966409 scopus 로고    scopus 로고
    • Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
    • Stein WD. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. Physiol Rev. 77:1997;545-590.
    • (1997) Physiol Rev , vol.77 , pp. 545-590
    • Stein, W.D.1
  • 35
    • 0029821995 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
    • Lautier D, Canitrot Y, Deeley RG, Cole SPC. Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem Pharmacol. 52:1996;967-977.
    • (1996) Biochem Pharmacol , vol.52 , pp. 967-977
    • Lautier, D.1    Canitrot, Y.2    Deeley, R.G.3    Cole, S.P.C.4
  • 36
    • 9544233652 scopus 로고    scopus 로고
    • A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
    • Taniguchi K, Wada M, Kohno K, Nakamura T, Kawabe T, Kawakami M, Kagotani K, Okumura K, Akiyama S, Kuwano M. A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res. 56:1996;4124-4129.
    • (1996) Cancer Res , vol.56 , pp. 4124-4129
    • Taniguchi, K.1    Wada, M.2    Kohno, K.3    Nakamura, T.4    Kawabe, T.5    Kawakami, M.6    Kagotani, K.7    Okumura, K.8    Akiyama, S.9    Kuwano, M.10
  • 37
    • 0028293986 scopus 로고
    • Presence and differential expression of SGLT1, GLUT1, GLUT2, GLUT3 and GLUT5 hexose-transporter mRNAs in Caco-2 cell clones in relation to cell growth and glucose consumption
    • Mahraoui L, Rodolosse A, Barbat A, Dussaulx E, Zweibaum A, Rousset M, Brot-Laroche E. Presence and differential expression of SGLT1, GLUT1, GLUT2, GLUT3 and GLUT5 hexose-transporter mRNAs in Caco-2 cell clones in relation to cell growth and glucose consumption. Biochem J. 298:1994;629-633.
    • (1994) Biochem J , vol.298 , pp. 629-633
    • Mahraoui, L.1    Rodolosse, A.2    Barbat, A.3    Dussaulx, E.4    Zweibaum, A.5    Rousset, M.6    Brot-Laroche, E.7
  • 39
    • 0030893978 scopus 로고    scopus 로고
    • Oral absorption and metabolism of quercetin and sugar-conjugated derivatives in specific transport systems
    • Noteborn HPJM, Jansen E, Benito S, Mengelers MJB. Oral absorption and metabolism of quercetin and sugar-conjugated derivatives in specific transport systems. Cancer Lett. 114:1997;175-177.
    • (1997) Cancer Lett , vol.114 , pp. 175-177
    • Noteborn, H.P.J.M.1    Jansen, E.2    Benito, S.3    Mengelers, M.J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.