Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs

Planta Medica

Volumn 62, Issue 4, 1996, Pages 289-292

  Merfort, Irmgard ^a,d   Heilmann, Jörg ^a   Weiss, Manfred ^a   Pietta, Piergiorgio ^b   Gardana, Claudio ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF MILAN   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

chemiluminescence; flavonoid metabolites; horseradish peroxidase; radical scavenger activity

Indexed keywords

3 HYDROXYPHENYLACETIC ACID; 3,4 DIHYDROXYPHENYLACETIC ACID; DRUG METABOLITE; FLAVONE; FLAVONOID; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LUMINOL; OXYGEN RADICAL; PHLORETIC ACID; PROCYANIDIN; QUERCETIN; QUERCETIN DERIVATIVE; SCAVENGER; UNCLASSIFIED DRUG; ZYMOSAN;

ARTICLE; CELL FREE SYSTEM; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; DRUG METABOLISM; HUMAN; HUMAN CELL; INTESTINE FLORA; NEUTROPHIL; SIGNAL TRANSDUCTION;

ARMORACIA RUSTICANA;

EID: 0029742815     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-957886     Document Type: Article

References (25)

1. Aruoma, O. I. (1994) Fd. Chem. Toxic. 32, 671-683.
2. Middleton, E., Kandaswami, C. (1986) in: The Flavonoids, Advances in Research since 1986, (Harborne, J. B., eds.), pp. 619-645, Chapman and Hall.
3. Heilmann, J., Merfort, I., Weiss, M. (1995) Planta Med. 61, 435-438.
4. Gugler, R., Leschik, M., Dengler, H. J. (1975) Eur. J. Clin. Pharmacol. 9, 229-234.
5. Booth, A. N., Murray, C. W., Jones, F. T., DeEds, F. (1956) J. Biol. Chem. 223, 251-257.
6. Das, N. P., Griffiths, L. A. (1969) Biochem. J. 115, 831-836.
7. Winter, J., Moore, L. H., Dowell, V. R., Bokkenheuser, V. D. (1989) Appl. Environ. Microbiol. 55, 1203-1208.
8. Baba, S., Furuta, T., Horie, M., Nakagawa, H. (1981) J. Pharm. Sci. 70, 780-782.
9. Siegers, C.-P., Röbke, A., Steffen, B., Guo, Z., Pentz, R. (1992) Naunyn-Schmiedeberg's Arch. Pharmacol. 345, R 40 (Suppl.) 159.
10. Sawai, Y., Kohsaka, K., Nishiyama, Y., Ando, K. (1987) Arzneim.-Forsch. 37, 729-732.
11. Pietta, P. G., Gardana, C., Mauri, P. L., Maffei-Facino, R., Carini, M. (1996) J. Chromatogr., in press.
12. Dahlgren, C. (1989) Free Radical Biol. Med. 6, 399-403.
13. Dahlgren, C., Stendahl, O. (1983) Infect. Immun. 39, 736-741.
14. Aniansson, H., Stendahl, O., Dahlgren, C. (1984) Acta Path. Microbiol. Immunol. Scand. Sect. C 92, 357-369.
15. Littaru, G. P., Lipps, S., DeSela, P., Oradei, A., Torre, F. D., Macri, M. (1984) Biochem. Biophys. Res. Commun. 119, 1056-1061.
16. Bors, W., Heller, W., Michel, C., Saran, M. (1990) in: Adv. Experimental Medicine and Biology, Antioxid. Ther. Prev. Med., (Emerit, I., ed.), Vol. 264, pp. 165-170, Plenum Press, New York.
17. t'Hart, B. A., Ip Vai Ching, T. R. A. M., van Dijk, H., Labadie, R. (1990) Chem.-Biol. Interact. 72, 323-335.
18. Limasset, B., Le Doucen, C., Dore, J.-C., Ojasoo, T., Damon, M., Crastes de Paulet, A. (1993) Biochem. Pharmacol. 46, 1257-1271.
19. Hu, J. P., Calomme, M., Lasure, A., De Bruyne, T., Pieters, L., Vlietinck, A., Vanden Berghe, D. A. (1995) Biol. Trace Elem. Res. 47, 327-331.
20. Hertog, M. G. L., Hollman, P. C. H., Katan, M. B., Kromhout, D. (1993) Nutr. Cancer 20, 21-29.
21. Wurm, G., Baumann, J., Geres, U. (1982) Dtsch. Apoth. Ztg. 122, 2062-2068.
22. Baumann, J., v. Bruchhausen, F., Wurm, G. (1979) Naunyn-Schmiedeberg's Arch. Pharmacol. 307, 73-78.
23. Weiss, M., Schneider, E. M., Liebert, S., Mettler, S., Lemoine, H. (1996) Intensive Care Med., submitted.
24. Weiss, M., Schneider, E. M., Tarnow, J., Mettler, S., Krone, M., Lemoine, H. (1995) Naunyn-Schmiedeberg's Arch. Pharmacol. 351, 128.
25. Odajima, T. (1971) Biochim. Biophys. Acta 235, 52-60.