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Moeller B.J., Dreher M.R., Rabbani Z.N., Schroeder T., Cao Y., Li C.Y., and Dewhirst M.W. Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Cancer Cell 8 (2005) 99-110
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(2005)
Cancer Cell
, vol.8
, pp. 99-110
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Moeller, B.J.1
Dreher, M.R.2
Rabbani, Z.N.3
Schroeder, T.4
Cao, Y.5
Li, C.Y.6
Dewhirst, M.W.7
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81
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33750630119
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Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
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This study shows the importance of HIF-2α in an additional tumor type. Furthermore, it suggests that some of the differences between HIF-1α and HIF-2α are due to differential stability under moderate hypoxia rather than distinct target genes.
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Holmquist-Mengelbier L., Fredlund E., Lofstedt T., Noguera R., Navarro S., Nilsson H., Pietras A., Vallon-Christersson J., Borg A., Gradin K., et al. Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype. Cancer Cell 10 (2006) 413-423. This study shows the importance of HIF-2α in an additional tumor type. Furthermore, it suggests that some of the differences between HIF-1α and HIF-2α are due to differential stability under moderate hypoxia rather than distinct target genes.
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(2006)
Cancer Cell
, vol.10
, pp. 413-423
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Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
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