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Volumn 580, Issue 12, 2006, Pages 2860-2868

Multiple functions of Notch signaling in self-renewing organs and cancer

Author keywords

Differentiation; Notch signaling; Oncogene; Stem cell; Tumor suppressor

Indexed keywords

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; NICASTRIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; PRESENILIN 1; PRESENILIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CSL; TRANSCRIPTION FACTOR HES 1; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

EID: 33646551228     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.024     Document Type: Short Survey
Times cited : (175)

References (53)
  • 2
    • 0036727125 scopus 로고    scopus 로고
    • Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
    • Fortini M.E. Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling. Nat. Rev. Mol. Cell. Biol. 3 (2002) 673-684
    • (2002) Nat. Rev. Mol. Cell. Biol. , vol.3 , pp. 673-684
    • Fortini, M.E.1
  • 3
    • 10944241544 scopus 로고    scopus 로고
    • Molecular mechanisms for morphogenesis of the central nervous system in mammals
    • Ishibashi M. Molecular mechanisms for morphogenesis of the central nervous system in mammals. Anat. Sci. Int. 79 (2004) 226-234
    • (2004) Anat. Sci. Int. , vol.79 , pp. 226-234
    • Ishibashi, M.1
  • 4
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: cell fate control and signal integration in development
    • Artavanis-Tsakonas S., Rand M.D., and Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 284 (1999) 770-776
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 5
    • 8444220513 scopus 로고    scopus 로고
    • Signaling pathways in intestinal development and cancer
    • Sancho E., Batlle E., and Clevers H. Signaling pathways in intestinal development and cancer. Annu. Rev. Cell Dev. Biol. 20 (2004) 695-723
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 695-723
    • Sancho, E.1    Batlle, E.2    Clevers, H.3
  • 6
    • 15544381570 scopus 로고    scopus 로고
    • Self-renewal and cancer of the gut: two sides of a coin
    • Radtke F., and Clevers H. Self-renewal and cancer of the gut: two sides of a coin. Science 307 (2005) 1904-1909
    • (2005) Science , vol.307 , pp. 1904-1909
    • Radtke, F.1    Clevers, H.2
  • 8
  • 10
    • 8444247084 scopus 로고    scopus 로고
    • Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
    • Milano J., McKay J., Dagenais C., Foster-Brown L., Pognan F., Gadient R., Jacobs R.T., Zacco A., Greenberg B., and Ciaccio P.J. Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol. Sci. 82 (2004) 341-358
    • (2004) Toxicol. Sci. , vol.82 , pp. 341-358
    • Milano, J.1    McKay, J.2    Dagenais, C.3    Foster-Brown, L.4    Pognan, F.5    Gadient, R.6    Jacobs, R.T.7    Zacco, A.8    Greenberg, B.9    Ciaccio, P.J.10
  • 13
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till J.E., and Mc C.E. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat. Res. 14 (1961) 213-222
    • (1961) Radiat. Res. , vol.14 , pp. 213-222
    • Till, J.E.1    Mc, C.E.2
  • 15
    • 16844366556 scopus 로고    scopus 로고
    • RBPj{kappa}-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
    • Robert-Moreno A., Espinosa L., de la Pompa J.L., and Bigas A. RBPj{kappa}-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development 132 (2005) 1117-1126
    • (2005) Development , vol.132 , pp. 1117-1126
    • Robert-Moreno, A.1    Espinosa, L.2    de la Pompa, J.L.3    Bigas, A.4
  • 18
    • 0031899677 scopus 로고    scopus 로고
    • Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
    • Bigas A., Martin D.I., and Milner L.A. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell Biol. 18 (1998) 2324-2333
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2324-2333
    • Bigas, A.1    Martin, D.I.2    Milner, L.A.3
  • 21
    • 0036529989 scopus 로고    scopus 로고
    • Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
    • Stier S., Cheng T., Dombkowski D., Carlesso N., and Scadden D.T. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 99 (2002) 2369-2378
    • (2002) Blood , vol.99 , pp. 2369-2378
    • Stier, S.1    Cheng, T.2    Dombkowski, D.3    Carlesso, N.4    Scadden, D.T.5
  • 24
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell M.A., Brose K., Paradis G., Conner A.S., and Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183 (1996) 1797-1806
    • (1996) J. Exp. Med. , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 26
    • 0035988246 scopus 로고    scopus 로고
    • Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
    • Han H., Tanigaki K., Yamamoto N., Kuroda K., Yoshimoto M., Nakahata T., Ikuta K., and Honjo T. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int. Immunol. 14 (2002) 637-645
    • (2002) Int. Immunol. , vol.14 , pp. 637-645
    • Han, H.1    Tanigaki, K.2    Yamamoto, N.3    Kuroda, K.4    Yoshimoto, M.5    Nakahata, T.6    Ikuta, K.7    Honjo, T.8
  • 30
    • 15244346226 scopus 로고    scopus 로고
    • Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation
    • Mancini S.J., Mantei N., Dumortier A., Suter U., Macdonald H.R., and Radtke F. Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood 105 (2005) 2340-2342
    • (2005) Blood , vol.105 , pp. 2340-2342
    • Mancini, S.J.1    Mantei, N.2    Dumortier, A.3    Suter, U.4    Macdonald, H.R.5    Radtke, F.6
  • 31
    • 17644382970 scopus 로고    scopus 로고
    • Regulation of lymphoid development, differentiation, and function by the Notch pathway
    • Maillard I., Fang T., and Pear W.S. Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annu. Rev. Immunol. 23 (2005) 945-974
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 945-974
    • Maillard, I.1    Fang, T.2    Pear, W.S.3
  • 32
    • 4644265888 scopus 로고    scopus 로고
    • Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors
    • Hoflinger S., Kesavan K., Fuxa M., Hutter C., Heavey B., Radtke F., and Busslinger M. Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J. Immunol. 173 (2004) 3935-3944
    • (2004) J. Immunol. , vol.173 , pp. 3935-3944
    • Hoflinger, S.1    Kesavan, K.2    Fuxa, M.3    Hutter, C.4    Heavey, B.5    Radtke, F.6    Busslinger, M.7
  • 33
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen L.W., Bird J., West D.C., Soreng A.L., Reynolds T.C., Smith S.D., and Sklar J. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66 (1991) 649-661
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3    Soreng, A.L.4    Reynolds, T.C.5    Smith, S.D.6    Sklar, J.7
  • 34
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear W.S., Aster J.C., Scott M.L., Hasserjian R.P., Soffer B., Sklar J., and Baltimore D. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183 (1996) 2283-2291
    • (1996) J. Exp. Med. , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3    Hasserjian, R.P.4    Soffer, B.5    Sklar, J.6    Baltimore, D.7
  • 37
    • 3342891403 scopus 로고    scopus 로고
    • Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression
    • Lefort K., and Dotto G.P. Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression. Semin. Cancer Biol. 14 (2004) 374-386
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 374-386
    • Lefort, K.1    Dotto, G.P.2
  • 38
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis G., Sun T.T., and Lavker R.M. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61 (1990) 1329-1337
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 39
    • 0035951372 scopus 로고    scopus 로고
    • Morphogenesis and renewal of hair follicles from adult multipotent stem cells
    • Oshima H., Rochat A., Kedzia C., Kobayashi K., and Barrandon Y. Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104 (2001) 233-245
    • (2001) Cell , vol.104 , pp. 233-245
    • Oshima, H.1    Rochat, A.2    Kedzia, C.3    Kobayashi, K.4    Barrandon, Y.5
  • 40
    • 4444290010 scopus 로고    scopus 로고
    • Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • Blanpain C., Lowry W.E., Geoghegan A., Polak L., and Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118 (2004) 635-648
    • (2004) Cell , vol.118 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Fuchs, E.5
  • 42
    • 0034682742 scopus 로고    scopus 로고
    • Involvement of follicular stem cells in forming not only the follicle but also the epidermis
    • Taylor G., Lehrer M.S., Jensen P.J., Sun T.T., and Lavker R.M. Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 102 (2000) 451-461
    • (2000) Cell , vol.102 , pp. 451-461
    • Taylor, G.1    Lehrer, M.S.2    Jensen, P.J.3    Sun, T.T.4    Lavker, R.M.5
  • 43
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • Ito M., Liu Y., Yang Z., Nguyen J., Liang F., Morris R.J., and Cotsarelis G. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat. Med. 11 (2005) 1351-1354
    • (2005) Nat. Med. , vol.11 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 44
    • 2942528798 scopus 로고    scopus 로고
    • Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing
    • Thelu J., Rossio P., and Favier B. Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing. BMC Dermatol. 2 (2002) 7
    • (2002) BMC Dermatol. , vol.2 , pp. 7
    • Thelu, J.1    Rossio, P.2    Favier, B.3
  • 45
    • 0034192461 scopus 로고    scopus 로고
    • Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
    • Lowell S., Jones P., Le Roux I., Dunne J., and Watt F.M. Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr. Biol. 10 (2000) 491-500
    • (2000) Curr. Biol. , vol.10 , pp. 491-500
    • Lowell, S.1    Jones, P.2    Le Roux, I.3    Dunne, J.4    Watt, F.M.5
  • 49
    • 23244452254 scopus 로고    scopus 로고
    • Notch1 is essential for postnatal hair follicle development and homeostasis
    • Vauclair S., Nicolas M., Barrandon Y., and Radtke F. Notch1 is essential for postnatal hair follicle development and homeostasis. Dev. Biol. 284 (2005) 184-193
    • (2005) Dev. Biol. , vol.284 , pp. 184-193
    • Vauclair, S.1    Nicolas, M.2    Barrandon, Y.3    Radtke, F.4
  • 50
    • 0037452751 scopus 로고    scopus 로고
    • Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells
    • Yamamoto N., Tanigaki K., Han H., Hiai H., and Honjo T. Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells. Curr. Biol. 13 (2003) 333-338
    • (2003) Curr. Biol. , vol.13 , pp. 333-338
    • Yamamoto, N.1    Tanigaki, K.2    Han, H.3    Hiai, H.4    Honjo, T.5
  • 51
    • 7744240345 scopus 로고    scopus 로고
    • gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis
    • Pan Y., Lin M.H., Tian X., Cheng H.T., Gridley T., Shen J., and Kopan R. gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev. Cell 7 (2004) 731-743
    • (2004) Dev. Cell , vol.7 , pp. 731-743
    • Pan, Y.1    Lin, M.H.2    Tian, X.3    Cheng, H.T.4    Gridley, T.5    Shen, J.6    Kopan, R.7
  • 52
    • 0033529790 scopus 로고    scopus 로고
    • p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential
    • Topley G.I., Okuyama R., Gonzales J.G., Conti C., and Dotto G.P. p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential. Proc. Natl. Acad. Sci. USA 96 (1999) 9089-9094
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9089-9094
    • Topley, G.I.1    Okuyama, R.2    Gonzales, J.G.3    Conti, C.4    Dotto, G.P.5
  • 53
    • 22344436360 scopus 로고    scopus 로고
    • p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • Devgan V., Mammucari C., Millar S.E., Brisken C., and Dotto G.P. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 19 (2005) 1485-1495
    • (2005) Genes Dev. , vol.19 , pp. 1485-1495
    • Devgan, V.1    Mammucari, C.2    Millar, S.E.3    Brisken, C.4    Dotto, G.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.