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Volumn 95, Issue 2, 2004, Pages 146-153

Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1

Author keywords

Angiogenesis; EPAS1; Flt 1; Hypoxia

Indexed keywords

ADENOVIRUS VECTOR; ANGIOPOIETIN RECEPTOR; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEIN; DEFEROXAMINE; ENDOTHELIAL PAS DOMAIN PROTEIN 1; GENE PRODUCT; HELIX LOOP HELIX PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 3343013829     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000134920.10128.b4     Document Type: Article
Times cited : (143)

References (37)
  • 1
    • 0035313697 scopus 로고    scopus 로고
    • HIF-1 and mechanisms of hypoxia sensing
    • Semenza GL. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol. 2001;13:167-171.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 167-171
    • Semenza, G.L.1
  • 2
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS 1), a transcription factor selectively expressed in endothelial cells
    • Tian H, McKnight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS 1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 1997;11:72-82.
    • (1997) Genes Dev , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 3
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
    • Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA. 1997;94:4273-4278.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 6
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
    • Peng J, Zhang L, Drysdale L, Fong GH. The transcription factor EPAS1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling. Proc Natl Acad Sci USA. 2000;97:8386-8391.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 7
    • 0032213236 scopus 로고    scopus 로고
    • The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    • Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev. 1998;12:3320-3324.
    • (1998) Genes Dev , vol.12 , pp. 3320-3324
    • Tian, H.1    Hammer, R.E.2    Matsumoto, A.M.3    Russell, D.W.4    McKnight, S.L.5
  • 9
    • 0344436031 scopus 로고    scopus 로고
    • Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice
    • Kappel A, Ronicke V, Damert A, Flamme I, Risau W, Breier G. Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice. Blood. 1999;93: 4284-4292.
    • (1999) Blood , vol.93 , pp. 4284-4292
    • Kappel, A.1    Ronicke, V.2    Damert, A.3    Flamme, I.4    Risau, W.5    Breier, G.6
  • 10
    • 0037470245 scopus 로고    scopus 로고
    • Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)
    • Elvert G, Kappel A, Heidenreich R, Englmeier U, Lanz S, Acker T, Rauter M, Plate K, Sieweke M, Breier G, Flamme I. Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). J Biol Chem. 2003;278:7520-7530.
    • (2003) J Biol Chem , vol.278 , pp. 7520-7530
    • Elvert, G.1    Kappel, A.2    Heidenreich, R.3    Englmeier, U.4    Lanz, S.5    Acker, T.6    Rauter, M.7    Plate, K.8    Sieweke, M.9    Breier, G.10    Flamme, I.11
  • 13
    • 0032560844 scopus 로고    scopus 로고
    • VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development
    • Larcher F, Murillas R, Bolontrade M, Conti CJ, Jorcano JL. VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development. Oncogene. 1998; 17:303-311.
    • (1998) Oncogene , vol.17 , pp. 303-311
    • Larcher, F.1    Murillas, R.2    Bolontrade, M.3    Conti, C.J.4    Jorcano, J.L.5
  • 14
    • 0037090776 scopus 로고    scopus 로고
    • Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
    • Dor Y, Djonov V, Abramovitch R, Itin A, Fishman GI, Carmeliet P, Goelman G, Keshet E. Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J. 2002;21:1939-1947.
    • (2002) EMBO J , vol.21 , pp. 1939-1947
    • Dor, Y.1    Djonov, V.2    Abramovitch, R.3    Itin, A.4    Fishman, G.I.5    Carmeliet, P.6    Goelman, G.7    Keshet, E.8
  • 17
    • 0032965317 scopus 로고    scopus 로고
    • Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF
    • Rivard A, Silver M, Chen D, Kearney M, Magner M, Annex B, Peters K, Isner JM. Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol. 1999;154: 355-363.
    • (1999) Am J Pathol , vol.154 , pp. 355-363
    • Rivard, A.1    Silver, M.2    Chen, D.3    Kearney, M.4    Magner, M.5    Annex, B.6    Peters, K.7    Isner, J.M.8
  • 18
    • 0034711261 scopus 로고    scopus 로고
    • CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression
    • Maemura K, de la Monte SM, Chin MT, Layne MD, Hsieh CM, Yet SF, Perrella MA, Lee ME, CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. J Biol Chem. 2000;275:36847-36851.
    • (2000) J Biol Chem , vol.275 , pp. 36847-36851
    • Maemura, K.1    De La Monte, S.M.2    Chin, M.T.3    Layne, M.D.4    Hsieh, C.M.5    Yet, S.F.6    Perrella, M.A.7    Lee, M.E.8
  • 19
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 20
    • 0141988698 scopus 로고    scopus 로고
    • Predominant role of hypoxia-inducible transcription factor (Hif)-lalpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
    • Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-lalpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res. 2003;63:6130-6134.
    • (2003) Cancer Res , vol.63 , pp. 6130-6134
    • Sowter, H.M.1    Raval, R.R.2    Moore, J.W.3    Ratcliffe, P.J.4    Harris, A.L.5
  • 21
    • 0018885287 scopus 로고
    • A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration
    • Falk W, Goodwin RH Jr, Leonard EJ. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods. 1980;33:239-247.
    • (1980) J Immunol Methods , vol.33 , pp. 239-247
    • Falk, W.1    Goodwin Jr., R.H.2    Leonard, E.J.3
  • 25
    • 0035827721 scopus 로고    scopus 로고
    • Clock genes in the heart: Characterization and attenuation with hypertrophy
    • Young ME, Razeghi P, Taegtmeyer H. Clock genes in the heart: characterization and attenuation with hypertrophy. Circ Res. 2001;88: 1142-1150.
    • (2001) Circ Res , vol.88 , pp. 1142-1150
    • Young, M.E.1    Razeghi, P.2    Taegtmeyer, H.3
  • 27
    • 0033593219 scopus 로고    scopus 로고
    • Oxygen-regulated and transactivating domains in endothelial PAS protein 1: Comparison with hypoxia-inducible factor-1alpha
    • O'Rourke JF, Tian YM, Ratcliffe PJ, Pugh CW. Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha. J Biol Chem. 1999;274:2060-2071.
    • (1999) J Biol Chem , vol.274 , pp. 2060-2071
    • O'Rourke, J.F.1    Tian, Y.M.2    Ratcliffe, P.J.3    Pugh, C.W.4
  • 28
    • 0035003384 scopus 로고    scopus 로고
    • Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
    • Shibuya M. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct. 2001;26:25-35.
    • (2001) Cell Struct Funct , vol.26 , pp. 25-35
    • Shibuya, M.1
  • 29
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem. 1997;272:23659- 23667.
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 30
    • 0035920244 scopus 로고    scopus 로고
    • Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways
    • Zeng H, Dvorak HF, Mukhopadhyay D. Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways. J Biol Chem. 2001;276:26969-26979.
    • (2001) J Biol Chem , vol.276 , pp. 26969-26979
    • Zeng, H.1    Dvorak, H.F.2    Mukhopadhyay, D.3
  • 34
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain RK. Molecular regulation of vessel maturation. Nat Med. 2003;9: 685-693.
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.