메뉴 건너뛰기




Volumn 75, Issue 3, 2004, Pages 428-433

Shielding the double-edged sword: Negative regulation of the innate immune system

Author keywords

Endotoxin; Innate immunity; IRAK M; Signaling; TLR

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CYTOKINE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE M; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHOTRANSFERASE; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 1542343954     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0703321     Document Type: Review
Times cited : (68)

References (77)
  • 1
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov, R., Janeway Jr., C. A. (1997) Innate immunity: the virtues of a nonclonal system of recognition. Cell 91, 295-298.
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 3
    • 0036644042 scopus 로고    scopus 로고
    • Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
    • Takeuchi, O., Sato, S., Horiuchi, T., Hoshino, K., Takeda, K., Dong, Z., Modlin, R. L., Akira, S. (2002) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J. Immunol. 169, 10-14.
    • (2002) J. Immunol. , vol.169 , pp. 10-14
    • Takeuchi, O.1    Sato, S.2    Horiuchi, T.3    Hoshino, K.4    Takeda, K.5    Dong, Z.6    Modlin, R.L.7    Akira, S.8
  • 4
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., Akira, S. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 5
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou, L., Holt, A. C., Medzhitov, R., Flavell, R. A. (2001) Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413, 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 8
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the LPS gene product
    • Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., Akira, S. (1999) Cutting edge: Toll-like receptor 4 (TLR4) -deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS gene product. J. Immunol. 162, 3749-3752.
    • (1999) J. Immunol. , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 12
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai, T., Adachi, O., Ogawa, T., Takeda, K., Akira, S. (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122.
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 13
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., Takeda, K., Kaisho, T. (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2, 675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 17
    • 0034655280 scopus 로고    scopus 로고
    • IL-1 receptor-associated kinase modulates host responsiveness to endotoxin
    • Swantek, J. L., Tsen, M. F., Cobb, M. H., Thomas, J. A. (2000) IL-1 receptor-associated kinase modulates host responsiveness to endotoxin. J. Immunol. 164, 4301-4306.
    • (2000) J. Immunol. , vol.164 , pp. 4301-4306
    • Swantek, J.L.1    Tsen, M.F.2    Cobb, M.H.3    Thomas, J.A.4
  • 19
    • 0037117543 scopus 로고    scopus 로고
    • IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
    • Li, S., Strelow, A., Fontana, E. J., Wesche, H. (2002) IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 99, 5567-5572.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5567-5572
    • Li, S.1    Strelow, A.2    Fontana, E.J.3    Wesche, H.4
  • 20
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao, Z., Henzel, W. J., Gao, X. (1996) IRAK: a kinase associated with the interleukin-1 receptor. Science 271, 1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 21
    • 0033516561 scopus 로고    scopus 로고
    • IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
    • Wesche, H., Gao, X., Li, X., Kirschning, C. J., Stark, G. R., Cao, Z. (1999) IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J. Biol. Chem. 274, 19403-19410.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19403-19410
    • Wesche, H.1    Gao, X.2    Li, X.3    Kirschning, C.J.4    Stark, G.R.5    Cao, Z.6
  • 22
    • 0031423761 scopus 로고    scopus 로고
    • MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., Henzel, W. J., Shillinglaw, W., Li, S., Cao, Z. (1997) MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7, 837-847.
    • (1997) Immunity , vol.7 , pp. 837-847
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 23
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • Zhang, F. X., Kirschning, C. J., Mancinelli, R., Xu, X. P., Jin, Y., Faure, E., Mantovani, A., Rothe, M., Muzio, M., Arditi, M. (1999) Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274, 7611-7614.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7611-7614
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3    Xu, X.P.4    Jin, Y.5    Faure, E.6    Mantovani, A.7    Rothe, M.8    Muzio, M.9    Arditi, M.10
  • 24
    • 0022411888 scopus 로고
    • Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
    • Beutler, B., Milsark, I. W., Cerami, A. C. (1985) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229, 869-871.
    • (1985) Science , vol.229 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.C.3
  • 26
    • 85025404652 scopus 로고
    • Tolerance to bacterial pyrogens. I. Factors influencing its development
    • Beeson, P. B. (1947) Tolerance to bacterial pyrogens. I. Factors influencing its development. J. Exp. Med. 86, 29-38.
    • (1947) J. Exp. Med. , vol.86 , pp. 29-38
    • Beeson, P.B.1
  • 27
    • 0013965646 scopus 로고
    • Mechanisms of endotoxin tolerance. IV. Specificity of the pyrogenic refractory state during continuous intravenous infusions of endotoxin
    • Greisman, S. E., Young, E. J., Woodward, W. E. (1966) Mechanisms of endotoxin tolerance. IV. Specificity of the pyrogenic refractory state during continuous intravenous infusions of endotoxin. J. Exp. Med. 124, 983-1000.
    • (1966) J. Exp. Med. , vol.124 , pp. 983-1000
    • Greisman, S.E.1    Young, E.J.2    Woodward, W.E.3
  • 28
    • 0029090285 scopus 로고
    • Molecular mechanism in tolerance to lipopolysaccharide
    • Ziegler-Heitbrock, H. W. (1995) Molecular mechanism in tolerance to lipopolysaccharide. J. Inflamm. 45, 13-26.
    • (1995) J. Inflamm. , vol.45 , pp. 13-26
    • Ziegler-Heitbrock, H.W.1
  • 29
    • 0025313398 scopus 로고
    • Differential cytokine induction by doses of lipopolysaccharide and monophosphoryl lipid A that result in equivalent early endotoxin tolerance
    • Henricson, B. E., Benjamin, W. R., Vogel, S. N. (1990) Differential cytokine induction by doses of lipopolysaccharide and monophosphoryl lipid A that result in equivalent early endotoxin tolerance. Infect. Immun. 58, 2429-2437.
    • (1990) Infect. Immun. , vol.58 , pp. 2429-2437
    • Henricson, B.E.1    Benjamin, W.R.2    Vogel, S.N.3
  • 30
    • 0029451351 scopus 로고
    • Monophosphoryl lipid A as a prophylactic for sepsis and septic shock
    • Gustafson, G. L., Rhodes, M. J., Hegel, T. (1995) Monophosphoryl lipid A as a prophylactic for sepsis and septic shock. Prog. Clin. Biol. Res. 392, 567-579.
    • (1995) Prog. Clin. Biol. Res. , vol.392 , pp. 567-579
    • Gustafson, G.L.1    Rhodes, M.J.2    Hegel, T.3
  • 31
    • 0031848913 scopus 로고    scopus 로고
    • Pulmonary and hepatic gene expression following cecal ligation and puncture: Monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration
    • Salkowski, C. A., Detore, G., Franks, A., Falk, M. C., Vogel, S. N. (1998) Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration. Infect. Immun. 66, 3569-3578.
    • (1998) Infect. Immun. , vol.66 , pp. 3569-3578
    • Salkowski, C.A.1    Detore, G.2    Franks, A.3    Falk, M.C.4    Vogel, S.N.5
  • 32
    • 0006150217 scopus 로고
    • Mechanisms of endotoxin tolerance. II. Relationship between endotoxin tolerance and reticuloendothelial system phagocytic activity in man
    • Greisman, S. E., Wagner, H. N., Iio, M., Hornik, R. B. (1964) Mechanisms of endotoxin tolerance. II. Relationship between endotoxin tolerance and reticuloendothelial system phagocytic activity in man. J. Exp. Med. 119, 241-264.
    • (1964) J. Exp. Med. , vol.119 , pp. 241-264
    • Greisman, S.E.1    Wagner, H.N.2    Iio, M.3    Hornik, R.B.4
  • 35
    • 0027289326 scopus 로고
    • Cytokine down-regulation in endotoxin tolerance
    • Mengozzi, M., Ghezzi, P. (1993) Cytokine down-regulation in endotoxin tolerance. Eur. Cytokine Netw. 4, 89-98.
    • (1993) Eur. Cytokine Netw. , vol.4 , pp. 89-98
    • Mengozzi, M.1    Ghezzi, P.2
  • 37
    • 0031712326 scopus 로고    scopus 로고
    • Hyporesponsiveness to lipopolysaccharide alters the composition of NF-κB binding to the regulatory regions of inducible nitric oxide synthase gene
    • Goldring, C. E., Reveneau, S., Pinard, D., Jeannin, J. F. (1998) Hyporesponsiveness to lipopolysaccharide alters the composition of NF-κB binding to the regulatory regions of inducible nitric oxide synthase gene. Eur. J. Immunol. 28, 2960-2970.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2960-2970
    • Goldring, C.E.1    Reveneau, S.2    Pinard, D.3    Jeannin, J.F.4
  • 38
    • 0032588289 scopus 로고    scopus 로고
    • NF-κB1 (p50) is upregulated in lipopolysaccharide tolerance and can block tumor necrosis factor gene expression
    • Kastenbauer, S., Ziegler-Heitbrock, H. W. (1999) NF-κB1 (p50) is upregulated in lipopolysaccharide tolerance and can block tumor necrosis factor gene expression. Infect. Immun. 67, 1553-1559.
    • (1999) Infect. Immun. , vol.67 , pp. 1553-1559
    • Kastenbauer, S.1    Ziegler-Heitbrock, H.W.2
  • 39
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression
    • Nomura, F., Akashi, S., Sakao, Y., Sato, S., Kawai, T., Matsumoto, M., Nakanishi, K., Kimoto, M., Miyake, K., Takeda, K., Akira, S. (2000) Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J. Immunol. 164, 3476-3479.
    • (2000) J. Immunol. , vol.164 , pp. 3476-3479
    • Nomura, F.1    Akashi, S.2    Sakao, Y.3    Sato, S.4    Kawai, T.5    Matsumoto, M.6    Nakanishi, K.7    Kimoto, M.8    Miyake, K.9    Takeda, K.10    Akira, S.11
  • 40
    • 0034725584 scopus 로고    scopus 로고
    • Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
    • Li, L., Cousart, S., Hu, J., McCall, C. E. (2000) Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells. J. Biol. Chem. 275, 23340-23345.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23340-23345
    • Li, L.1    Cousart, S.2    Hu, J.3    McCall, C.E.4
  • 41
    • 0036838930 scopus 로고    scopus 로고
    • Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells
    • Medvedev, A. E., Lentschat, A., Wahl, L. M., Golenbock, D. T., Vogel, S. N. (2002) Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells. J. Immunol. 169, 5209-5216.
    • (2002) J. Immunol. , vol.169 , pp. 5209-5216
    • Medvedev, A.E.1    Lentschat, A.2    Wahl, L.M.3    Golenbock, D.T.4    Vogel, S.N.5
  • 42
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
    • Lehner, M. D., Morath, S., Michelsen, K. S., Schumann, R. R., Hartung, T. (2001) Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166, 5161-5167.
    • (2001) J. Immunol. , vol.166 , pp. 5161-5167
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3    Schumann, R.R.4    Hartung, T.5
  • 43
    • 0034671772 scopus 로고    scopus 로고
    • Synergy and cross-tolerance between Toll-like receptor (TLR)2- and TLR4-mediated signaling pathways
    • Sato, S., Nomura, F., Kawai, T., Takeuchi, O., Muhlradt, P. F., Takeda, K., Akira, S. (2000) Synergy and cross-tolerance between Toll-like receptor (TLR)2- and TLR4-mediated signaling pathways. J. Immunol. 165, 7096-7101.
    • (2000) J. Immunol. , vol.165 , pp. 7096-7101
    • Sato, S.1    Nomura, F.2    Kawai, T.3    Takeuchi, O.4    Muhlradt, P.F.5    Takeda, K.6    Akira, S.7
  • 44
    • 0036319517 scopus 로고    scopus 로고
    • A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways
    • Sato, S., Takeuchi, O., Fujita, T., Tomizawa, H., Takeda, K., Akira, S. (2002) A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int. Immunol. 14, 783-791.
    • (2002) Int. Immunol. , vol.14 , pp. 783-791
    • Sato, S.1    Takeuchi, O.2    Fujita, T.3    Tomizawa, H.4    Takeda, K.5    Akira, S.6
  • 45
    • 0037438350 scopus 로고    scopus 로고
    • CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: Alterations in IL-1 receptor-associated kinase expression
    • Yeo, S. J., Yoon, J. G., Hong, S. C., Yi, A. K. (2003) CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170, 1052-1061.
    • (2003) J. Immunol. , vol.170 , pp. 1052-1061
    • Yeo, S.J.1    Yoon, J.G.2    Hong, S.C.3    Yi, A.K.4
  • 46
    • 0034445697 scopus 로고    scopus 로고
    • Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
    • Cario, E., Podolsky, D. K. (2000) Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect. Immun. 68, 7010-7017.
    • (2000) Infect. Immun. , vol.68 , pp. 7010-7017
    • Cario, E.1    Podolsky, D.K.2
  • 47
    • 0035000687 scopus 로고    scopus 로고
    • Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium
    • Naik, S., Kelly, E. J., Meijer, L., Pettersson, S., Sanderson, I. R. (2001) Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium. J. Pediatr. Gastroenterol. Nutr. 32, 449-453.
    • (2001) J. Pediatr. Gastroenterol. Nutr. , vol.32 , pp. 449-453
    • Naik, S.1    Kelly, E.J.2    Meijer, L.3    Pettersson, S.4    Sanderson, I.R.5
  • 48
    • 0036499128 scopus 로고    scopus 로고
    • Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like receptor 4-mediated signaling
    • Fichorova, R. N., Cronin, A. O., Lien, E., Anderson, D. J., Ingalls, R. R. (2002) Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like receptor 4-mediated signaling. J. Immunol. 168, 2424-2432.
    • (2002) J. Immunol. , vol.168 , pp. 2424-2432
    • Fichorova, R.N.1    Cronin, A.O.2    Lien, E.3    Anderson, D.J.4    Ingalls, R.R.5
  • 49
    • 0006422025 scopus 로고    scopus 로고
    • The innate immune response of the respiratory epithelium
    • Diamond, G., Legarda, D., Ryan, L. K. (2000) The innate immune response of the respiratory epithelium. Immunol. Rev. 173, 27-38.
    • (2000) Immunol. Rev. , vol.173 , pp. 27-38
    • Diamond, G.1    Legarda, D.2    Ryan, L.K.3
  • 50
    • 0035076194 scopus 로고    scopus 로고
    • Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract
    • Backhed, F., Soderhall, M., Ekman, P., Normark, S., Richter-Dahlfors, A. (2001) Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract. Cell. Microbiol. 3, 153-158.
    • (2001) Cell. Microbiol. , vol.3 , pp. 153-158
    • Backhed, F.1    Soderhall, M.2    Ekman, P.3    Normark, S.4    Richter-Dahlfors, A.5
  • 51
    • 0037369767 scopus 로고    scopus 로고
    • CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli
    • Schilling, J. D., Martin, S. M., Hunstad, D. A., Patel, K. P., Mulvey, M. A., Justice, S. S., Lorenz, R. G., Hultgren, S. J. (2003) CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect. Immun. 71, 1470-1480.
    • (2003) Infect. Immun. , vol.71 , pp. 1470-1480
    • Schilling, J.D.1    Martin, S.M.2    Hunstad, D.A.3    Patel, K.P.4    Mulvey, M.A.5    Justice, S.S.6    Lorenz, R.G.7    Hultgren, S.J.8
  • 52
    • 0037307854 scopus 로고    scopus 로고
    • Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: Implications for host-microbial interactions in the gut
    • Melmed, G., Thomas, L. S., Lee, N., Tesfay, S. Y., Lukasek, K., Michelsen, K. S., Zhou, Y., Hu, B., Arditi, M., Abreu, M. T. (2003) Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J. Immunol. 170, 1406-1415.
    • (2003) J. Immunol. , vol.170 , pp. 1406-1415
    • Melmed, G.1    Thomas, L.S.2    Lee, N.3    Tesfay, S.Y.4    Lukasek, K.5    Michelsen, K.S.6    Zhou, Y.7    Hu, B.8    Arditi, M.9    Abreu, M.T.10
  • 53
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
    • Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J., Madara, J. L. (2001) Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167, 1882-1885.
    • (2001) J. Immunol. , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 54
    • 0035881949 scopus 로고    scopus 로고
    • Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4
    • Medvedev, A. E., Henneke, P., Schromm, A., Lien, E., Ingalls, R., Fenton, M. J., Golenbock, D. T., Vogel, S. N. (2001) Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. J. Immunol. 167, 2257-2267.
    • (2001) J. Immunol. , vol.167 , pp. 2257-2267
    • Medvedev, A.E.1    Henneke, P.2    Schromm, A.3    Lien, E.4    Ingalls, R.5    Fenton, M.J.6    Golenbock, D.T.7    Vogel, S.N.8
  • 55
    • 0037226519 scopus 로고    scopus 로고
    • Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance
    • Medvedev, A. E., Vogel, S. N. (2003) Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance. J. Endotoxin Res. 9, 60-64.
    • (2003) J. Endotoxin Res. , vol.9 , pp. 60-64
    • Medvedev, A.E.1    Vogel, S.N.2
  • 57
    • 0030694108 scopus 로고    scopus 로고
    • IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
    • Muzio, M., Ni, J., Feng, P., Dixit, V. M. (1997) IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278, 1612-1615.
    • (1997) Science , vol.278 , pp. 1612-1615
    • Muzio, M.1    Ni, J.2    Feng, P.3    Dixit, V.M.4
  • 63
    • 0025271844 scopus 로고
    • Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin
    • Dixit, V. M., Green, S., Sarma, V., Holzman, L. B., Wolf, F. W., O'Rourke, K., Ward, P. A., Prochownik, E. V., Marks, R. M. (1990) Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin. J. Biol. Chem. 265, 2973-2978.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2973-2978
    • Dixit, V.M.1    Green, S.2    Sarma, V.3    Holzman, L.B.4    Wolf, F.W.5    O'Rourke, K.6    Ward, P.A.7    Prochownik, E.V.8    Marks, R.M.9
  • 64
    • 0025179989 scopus 로고
    • The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein
    • Opipari Jr., A. W., Boguski, M. S., Dixit, V. M. (1990) The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein. J. Biol. Chem. 265, 14705-14708.
    • (1990) J. Biol. Chem. , vol.265 , pp. 14705-14708
    • Opipari Jr., A.W.1    Boguski, M.S.2    Dixit, V.M.3
  • 65
    • 0029073035 scopus 로고
    • Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis
    • Sarma, V., Lin, Z., Clark, L., Rust, B. M., Tewari, M., Noelle, R. J., Dixit, V. M. (1995) Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis. J. Biol. Chem. 270, 12343-12346.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12343-12346
    • Sarma, V.1    Lin, Z.2    Clark, L.3    Rust, B.M.4    Tewari, M.5    Noelle, R.J.6    Dixit, V.M.7
  • 66
    • 0026465540 scopus 로고
    • The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor κB
    • Laherty, C. D., Hu, H. M., Opipari, A. W., Wang, F., Dixit, V. M. (1992) The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor κB. J. Biol. Chem. 267, 24157-24160.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24157-24160
    • Laherty, C.D.1    Hu, H.M.2    Opipari, A.W.3    Wang, F.4    Dixit, V.M.5
  • 67
    • 0026699666 scopus 로고
    • Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by κB elements
    • Krikos, A., Laherty, C. D., Dixit, V. M. (1992) Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by κB elements. J. Biol. Chem. 267, 17971-17976.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17971-17976
    • Krikos, A.1    Laherty, C.D.2    Dixit, V.M.3
  • 68
    • 0030026698 scopus 로고    scopus 로고
    • A20 zinc finger protein inhibits TNF and IL-1 signaling
    • Jaattela, M., Mouritzen, H., Elling, F., Bastholm, L. (1996) A20 zinc finger protein inhibits TNF and IL-1 signaling. J. Immunol. 156, 1166-1173.
    • (1996) J. Immunol. , vol.156 , pp. 1166-1173
    • Jaattela, M.1    Mouritzen, H.2    Elling, F.3    Bastholm, L.4
  • 69
    • 0034730713 scopus 로고    scopus 로고
    • Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
    • Lee, E. G., Boone, D. L., Chai, S., Libby, S. L., Chien, M., Lodolce, J. P., Ma, A. (2000) Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice. Science 289, 2350-2354.
    • (2000) Science , vol.289 , pp. 2350-2354
    • Lee, E.G.1    Boone, D.L.2    Chai, S.3    Libby, S.L.4    Chien, M.5    Lodolce, J.P.6    Ma, A.7
  • 70
    • 0037418749 scopus 로고    scopus 로고
    • Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein
    • O'Reilly, S. M., Moynagh, P. N. (2003) Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein. Biochem. Biophys. Res. Commun. 303, 586-593.
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 586-593
    • O'Reilly, S.M.1    Moynagh, P.N.2
  • 71
    • 0033712615 scopus 로고    scopus 로고
    • Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
    • Zhang, S. Q., Kovalenko, A., Cantarella, G., Wallach, D. (2000) Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation. Immunity 12, 301-311.
    • (2000) Immunity , vol.12 , pp. 301-311
    • Zhang, S.Q.1    Kovalenko, A.2    Cantarella, G.3    Wallach, D.4
  • 72
    • 0033612571 scopus 로고    scopus 로고
    • The zinc finger protein A20 inhibits TNF-induced NF-κB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-κB-inhibiting protein ABIN
    • Heyninck, K., De Valck, D., Vanden Berghe, W., Van Criekinge, W., Contreras, R., Fiers, W., Haegeman, G., Beyaert, R. (1999) The zinc finger protein A20 inhibits TNF-induced NF-κB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-κB-inhibiting protein ABIN. J. Cell Biol. 145, 1471-1482.
    • (1999) J. Cell Biol. , vol.145 , pp. 1471-1482
    • Heyninck, K.1    De Valck, D.2    Vanden Berghe, W.3    Van Criekinge, W.4    Contreras, R.5    Fiers, W.6    Haegeman, G.7    Beyaert, R.8
  • 73
    • 0035839424 scopus 로고    scopus 로고
    • Identification of a novel A20-binding inhibitor of nuclear factor-κB activation termed ABIN-2
    • Van Huffel, S., Delaei, F., Heyninck, K., De Valck, D., Beyaert, R. (2001) Identification of a novel A20-binding inhibitor of nuclear factor-κB activation termed ABIN-2, J. Biol. Chem. 276, 30216-30223.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30216-30223
    • Van Huffel, S.1    Delaei, F.2    Heyninck, K.3    De Valck, D.4    Beyaert, R.5
  • 75
    • 0036510366 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor-mediated signaling by Tollip
    • Zhang, G., Ghosh, S. (2002) Negative regulation of Toll-like receptor-mediated signaling by Tollip. J. Biol. Chem. 277, 7059-7065.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7059-7065
    • Zhang, G.1    Ghosh, S.2
  • 76
    • 0036006290 scopus 로고    scopus 로고
    • Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88
    • Janssens, S., Burns, K., Tschopp, J., Beyaert, R. (2002) Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88. Curr. Biol. 12, 467-471.
    • (2002) Curr. Biol. , vol.12 , pp. 467-471
    • Janssens, S.1    Burns, K.2    Tschopp, J.3    Beyaert, R.4
  • 77
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns, K., Janssens, S., Brissoni, B., Olivos, N., Beyaert, R., Tschopp, J. (2003) Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197, 263-268.
    • (2003) J. Exp. Med. , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3    Olivos, N.4    Beyaert, R.5    Tschopp, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.