-
1
-
-
0034672321
-
Use of sulfobutyl ether beta-cyclodextrin as a vehicle for D-threo-1-phenyl-2-decanoylamino-3-morpholinopropanol-relat ed glucosylceramide synthase inhibitors
-
Abe A, Gregory S, Lee L, and Shayman JA. Use of sulfobutyl ether beta-cyclodextrin as a vehicle for D-threo-1-phenyl-2-decanoylamino-3- morpholinopropanol-relat ed glucosylceramide synthase inhibitors. Anal Biochem 287: 344-347, 2000.
-
(2000)
Anal Biochem
, vol.287
, pp. 344-347
-
-
Abe, A.1
Gregory, S.2
Lee, L.3
Shayman, J.A.4
-
2
-
-
0042471938
-
Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria
-
Epub 2003 Aug 24
-
Anes E, Kuhnel MP, Bos E, Moniz-Pereira J, Habermann A, and Griffiths G. Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria. Nat Cell Biol 5: 793-802, 2003. Epub 2003 Aug 24.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 793-802
-
-
Anes, E.1
Kuhnel, M.P.2
Bos, E.3
Moniz-Pereira, J.4
Habermann, A.5
Griffiths, G.6
-
3
-
-
0034003333
-
A critical role for telomeres in suppressing and facilitating carcinogenesis
-
Artandi SE and DePinho RA. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr Opin Genet Dev 10: 39-46, 2000.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 39-46
-
-
Artandi, S.E.1
DePinho, R.A.2
-
4
-
-
0031019745
-
Isolation of putative progenitor endothelial cells for angiogenesis
-
Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, and Isner JM. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967, 1997.
-
(1997)
Science
, vol.275
, pp. 964-967
-
-
Asahara, T.1
Murohara, T.2
Sullivan, A.3
Silver, M.4
Van Der Zee, R.5
Li, T.6
Witzenbichler, B.7
Schatteman, G.8
Isner, J.M.9
-
5
-
-
0033565540
-
VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
-
Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, and Isner JM. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 18: 3964-3972, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 3964-3972
-
-
Asahara, T.1
Takahashi, T.2
Masuda, H.3
Kalka, C.4
Chen, D.5
Iwaguro, H.6
Inai, Y.7
Silver, M.8
Isner, J.M.9
-
6
-
-
0038814315
-
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes
-
Epub 2003 Apr 3
-
Assmus B, Urbich C, Aicher A, Hofmann WK, Haendeler J, Rossig L, Spyridopoulos I, Zeiher AM, and Dimmeler S. HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes. Circ Res 92: 1049-1055, 2003. Epub 2003 Apr 3.
-
(2003)
Circ Res
, vol.92
, pp. 1049-1055
-
-
Assmus, B.1
Urbich, C.2
Aicher, A.3
Hofmann, W.K.4
Haendeler, J.5
Rossig, L.6
Spyridopoulos, I.7
Zeiher, A.M.8
Dimmeler, S.9
-
7
-
-
0036346816
-
Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages
-
Balin AK, Fisher AJ, Anzelone M, Leong I, and Allen RG. Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages. Exp Cell Res 274: 275-287, 2002.
-
(2002)
Exp Cell Res
, vol.274
, pp. 275-287
-
-
Balin, A.K.1
Fisher, A.J.2
Anzelone, M.3
Leong, I.4
Allen, R.G.5
-
8
-
-
0036468514
-
Effects of ambient oxygen concentration on the growth and antioxidant defenses of of human cell cultures established from fetal and postnatal skin
-
Balin AK, Pratt L, and Allen RG. Effects of ambient oxygen concentration on the growth and antioxidant defenses of of human cell cultures established from fetal and postnatal skin. Free Radic Biol Med 32: 257-267, 2002.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 257-267
-
-
Balin, A.K.1
Pratt, L.2
Allen, R.G.3
-
9
-
-
0034893715
-
The role of AGEs in aging: Causation or correlation
-
Baynes JW. The role of AGEs in aging: causation or correlation. Exp Gerontol 36: 1527-1537, 2001.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1527-1537
-
-
Baynes, J.W.1
-
10
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, and Campisi J. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J 22: 4212-4222, 2003.
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
11
-
-
5444271778
-
Stem cells, aging, and cancer: Inevitabilities and outcomes
-
Bell DR and Van Zant G. Stem cells, aging, and cancer: inevitabilities and outcomes. Oncogene 23: 7290-7296, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 7290-7296
-
-
Bell, D.R.1
Van Zant, G.2
-
12
-
-
14644410453
-
The signals and pathways activating cellular senescence
-
Epub 2004 Dec 30
-
Ben-Porath I and Weinberg RA. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 37: 961-976, 2005. Epub 2004 Dec 30.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 961-976
-
-
Ben-Porath, I.1
Weinberg, R.A.2
-
13
-
-
13844271818
-
Neural stem cells as therapeutic agents for age-related brain repair
-
Bernal GM and Peterson DA. Neural stem cells as therapeutic agents for age-related brain repair. Aging Cell 3: 345-351, 2004.
-
(2004)
Aging Cell
, vol.3
, pp. 345-351
-
-
Bernal, G.M.1
Peterson, D.A.2
-
15
-
-
17144429302
-
Calorie restriction, SIRT1 and metabolism: Understanding longevity
-
Bordone L and Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol 6: 298-305, 2005.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
16
-
-
0035937503
-
Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism
-
Breitschopf K, Zeiher AM, and Dimmeler S. Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism. FEBS Lett 493: 21-25, 2001.
-
(2001)
FEBS Lett
, vol.493
, pp. 21-25
-
-
Breitschopf, K.1
Zeiher, A.M.2
Dimmeler, S.3
-
17
-
-
0034028836
-
Tumor suppressors and oncogenes in cellular senescence
-
Bringold F and Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol 35: 317-329, 2000.
-
(2000)
Exp Gerontol
, vol.35
, pp. 317-329
-
-
Bringold, F.1
Serrano, M.2
-
18
-
-
1242275127
-
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen
-
Epub 2003 Dec 11
-
Brodsky SV, Gealekman O, Chen J, Zhang F, Togashi N, Crabtree M, Gross SS, Nasjletti A, and Goligorsky MS. Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. Circ Res 94: 377-384, 2004. Epub 2003 Dec 11.
-
(2004)
Circ Res
, vol.94
, pp. 377-384
-
-
Brodsky, S.V.1
Gealekman, O.2
Chen, J.3
Zhang, F.4
Togashi, N.5
Crabtree, M.6
Gross, S.S.7
Nasjletti, A.8
Goligorsky, M.S.9
-
20
-
-
3242708498
-
Contribution of p16(INK4a) to replicative senescence of human fibroblasts
-
Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J, and Peters G. Contribution of p16(INK4a) to replicative senescence of human fibroblasts. Exp Cell Res 298: 549-559, 2004.
-
(2004)
Exp Cell Res
, vol.298
, pp. 549-559
-
-
Brookes, S.1
Rowe, J.2
Gutierrez Del Arroyo, A.3
Bond, J.4
Peters, G.5
-
21
-
-
18444380541
-
INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence
-
Brookes S, Rowe J, Ruas M, Llanos S, Clark PA, Lomax M, James MC, Vatcheva R, Bates S, Vousden KH, Parry D, Gruis N, Smit N, Bergman W, and Peters G. INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence. EMBO J 21: 2936-2945, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 2936-2945
-
-
Brookes, S.1
Rowe, J.2
Ruas, M.3
Llanos, S.4
Clark, P.A.5
Lomax, M.6
James, M.C.7
Vatcheva, R.8
Bates, S.9
Vousden, K.H.10
Parry, D.11
Gruis, N.12
Smit, N.13
Bergman, W.14
Peters, G.15
-
22
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820, 2001.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
23
-
-
0023950461
-
Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
-
Brownlee M, Cerami A, and Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 318: 1315-1321, 1988.
-
(1988)
N Engl J Med
, vol.318
, pp. 1315-1321
-
-
Brownlee, M.1
Cerami, A.2
Vlassara, H.3
-
24
-
-
0035500487
-
Cellular senescence as a tumor-suppressor mechanism
-
Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11: S27-S31, 2001.
-
(2001)
Trends Cell Biol
, vol.11
-
-
Campisi, J.1
-
25
-
-
0031755297
-
The role of cellular senescence in skin aging
-
Campisi J. The role of cellular senescence in skin aging. J Investig Dermatol Symp Proc 3: 1-5, 1998.
-
(1998)
J Investig Dermatol Symp Proc
, vol.3
, pp. 1-5
-
-
Campisi, J.1
-
26
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522, 2005.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
27
-
-
24944573014
-
Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease
-
First published May 31, 2005; doi:10.1152/ajprenal.00127.2005
-
Chan CT, Li SH, and Verma S. Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease. Am J Physiol Renal Physiol 289: F679-F684, 2005. First published May 31, 2005; doi:10.1152/ajprenal.00127.2005.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
-
-
Chan, C.T.1
Li, S.H.2
Verma, S.3
-
28
-
-
4344625264
-
Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: Prevention by chronic therapy with a peroxynitrite scavenger ebselen
-
Chander PN, Gealekman O, Brodsky SV, Elitok S, Tojo A, Crabtree M, Gross SS, and Goligorsky MS. Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen. J Am Soc Nephrol 15: 2391-2403, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2391-2403
-
-
Chander, P.N.1
Gealekman, O.2
Brodsky, S.V.3
Elitok, S.4
Tojo, A.5
Crabtree, M.6
Gross, S.S.7
Goligorsky, M.S.8
-
29
-
-
0031048334
-
Advanced glycation end products, oxidant stress and vascular lesions
-
Chappey O, Dosquet C, Wautier MP, and Wautier JL. Advanced glycation end products, oxidant stress and vascular lesions. Eur J Clin Invest 27: 97-108, 1997.
-
(1997)
Eur J Clin Invest
, vol.27
, pp. 97-108
-
-
Chappey, O.1
Dosquet, C.2
Wautier, M.P.3
Wautier, J.L.4
-
30
-
-
0037188926
-
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells
-
Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS, and Goligorsky MS. Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells. Circ Res 90: 1290-1298, 2002.
-
(2002)
Circ Res
, vol.90
, pp. 1290-1298
-
-
Chen, J.1
Brodsky, S.V.2
Goligorsky, D.M.3
Hampel, D.J.4
Li, H.5
Gross, S.S.6
Goligorsky, M.S.7
-
31
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
Chen Q and Ames BN. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci USA 91: 4130-4134, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
32
-
-
0033913425
-
Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints
-
Chen QM. Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints. Ann NY Acad Sci 908: 111-125, 2000.
-
(2000)
Ann NY Acad Sci
, vol.908
, pp. 111-125
-
-
Chen, Q.M.1
-
34
-
-
10744219959
-
Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure
-
Epub 2003 Sep 4
-
Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, Di Meglio F, Nadal-Ginard B, Frustaci A, Leri A, Maseri A, and Anversa P. Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ Res 93: 604-613, 2003. Epub 2003 Sep 4.
-
(2003)
Circ Res
, vol.93
, pp. 604-613
-
-
Chimenti, C.1
Kajstura, J.2
Torella, D.3
Urbanek, K.4
Heleniak, H.5
Colussi, C.6
Di Meglio, F.7
Nadal-Ginard, B.8
Frustaci, A.9
Leri, A.10
Maseri, A.11
Anversa, P.12
-
35
-
-
0042346366
-
Senescent phenotype can be reversed by reduction of caveolin status
-
Epub May 1, 2003
-
Cho KA, Ryu SJ, Park JS, Jang IS, Ahn JS, Kim KT, and Park SC. Senescent phenotype can be reversed by reduction of caveolin status. J Biol Chem 278: 27789-27795, 2003. Epub May 1, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 27789-27795
-
-
Cho, K.A.1
Ryu, S.J.2
Park, J.S.3
Jang, I.S.4
Ahn, J.S.5
Kim, K.T.6
Park, S.C.7
-
36
-
-
3042734510
-
Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure
-
Choi JH, Kim KL, Huh W, Kim B, Byun J, Suh W, Sung J, Jeon ES, Oh HY, and Kim DK. Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 24: 1246-1252, 2004.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1246-1252
-
-
Choi, J.H.1
Kim, K.L.2
Huh, W.3
Kim, B.4
Byun, J.5
Suh, W.6
Sung, J.7
Jeon, E.S.8
Oh, H.Y.9
Kim, D.K.10
-
37
-
-
0029089162
-
Senescence-dependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells
-
Comi P, Chiaramonte R, and Maier JA. Senescence-dependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells. Exp Cell Res 219: 304-308, 1995.
-
(1995)
Exp Cell Res
, vol.219
, pp. 304-308
-
-
Comi, P.1
Chiaramonte, R.2
Maier, J.A.3
-
38
-
-
8444237735
-
Genetic manipulation of telomerase in HIV-specific CD8+ T cells: Enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization
-
Dagarag M, Evazyan T, Rao N, and Effros RB. Genetic manipulation of telomerase in HIV-specific CD8+ T cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization. J Immunol 173: 6303-6311, 2004.
-
(2004)
J Immunol
, vol.173
, pp. 6303-6311
-
-
Dagarag, M.1
Evazyan, T.2
Rao, N.3
Effros, R.B.4
-
39
-
-
0033635597
-
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
-
Dannenberg JH, van Rossum A, Schuijff L, and te Riele H. Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev 14: 3051-3064, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
Van Rossum, A.2
Schuijff, L.3
Te Riele, H.4
-
40
-
-
0346463059
-
High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts
-
Epub Oct 29, 2003
-
Deng Q, Liao R, Wu BL, and Sun P. High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts. J Biol Chem 279: 1050-1059, 2004. Epub Oct 29, 2003.
-
(2004)
J Biol Chem
, vol.279
, pp. 1050-1059
-
-
Deng, Q.1
Liao, R.2
Wu, B.L.3
Sun, P.4
-
41
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocke M, and Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
Peacocke, M.11
Campisi, J.12
-
42
-
-
0036467483
-
Immortalisation and transformation revisited
-
Drayton S and Peters G. Immortalisation and transformation revisited. Curr Opin Genet Dev 12: 98-104, 2002.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 98-104
-
-
Drayton, S.1
Peters, G.2
-
43
-
-
0029877250
-
Insights on immunological aging derived from the T lymphocyte cellular senescence model
-
Effros RB. Insights on immunological aging derived from the T lymphocyte cellular senescence model. Exp Gerontol 31: 21-27, 1996.
-
(1996)
Exp Gerontol
, vol.31
, pp. 21-27
-
-
Effros, R.B.1
-
45
-
-
0035146421
-
Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries
-
Fenton M, Barker S, Kurz DJ, and Erusalimsky JD. Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries. Arterioscler Thromb Vasc Biol 21: 220-226, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 220-226
-
-
Fenton, M.1
Barker, S.2
Kurz, D.J.3
Erusalimsky, J.D.4
-
46
-
-
0036237039
-
Oncogenic ras and p53 cooperate to induce cellular senescence
-
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, and Lowe SW. Oncogenic ras and p53 cooperate to induce cellular senescence. Mol Cell Biol 22: 3497-3508, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3497-3508
-
-
Ferbeyre, G.1
De Stanchina, E.2
Lin, A.W.3
Querido, E.4
McCurrach, M.E.5
Hannon, G.J.6
Lowe, S.W.7
-
47
-
-
21644467118
-
Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: Amelioration with Ebselen
-
Gealekman O, Brodsky SV, Zhang F, Chander PN, Friedli C, Nasjletti A, and Goligorsky MS. Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen. Kidney Int 66: 2337-2347, 2004.
-
(2004)
Kidney Int
, vol.66
, pp. 2337-2347
-
-
Gealekman, O.1
Brodsky, S.V.2
Zhang, F.3
Chander, P.N.4
Friedli, C.5
Nasjletti, A.6
Goligorsky, M.S.7
-
48
-
-
21644467118
-
Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: Amelioration with Ebselen
-
Gealekman O, Brodsky SV, Zhang F, Chander PN, Friedli C, Nasjletti A, Goligorsky MS, Elitok S, Tojo A, Crabtree M, Gross SS, Chen J, and Togashi N. Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen. Kidney Int 66: 2337-2347, 2004.
-
(2004)
Kidney Int
, vol.66
, pp. 2337-2347
-
-
Gealekman, O.1
Brodsky, S.V.2
Zhang, F.3
Chander, P.N.4
Friedli, C.5
Nasjletti, A.6
Goligorsky, M.S.7
Elitok, S.8
Tojo, A.9
Crabtree, M.10
Gross, S.S.11
Chen, J.12
Togashi, N.13
-
49
-
-
0034658662
-
In vitro differentiation of endothelial cells from AC133-positive progenitor cells
-
Gehling UM, Ergun S, Schumacher U, Wagener C, Pantel K, Otte M, Schuch G, Schafhausen P, Mende T, Kilic N, Kluge K, Schafer B, Hossfeld DK, and Fiedler W. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 95: 3106-3112, 2000.
-
(2000)
Blood
, vol.95
, pp. 3106-3112
-
-
Gehling, U.M.1
Ergun, S.2
Schumacher, U.3
Wagener, C.4
Pantel, K.5
Otte, M.6
Schuch, G.7
Schafhausen, P.8
Mende, T.9
Kilic, N.10
Kluge, K.11
Schafer, B.12
Hossfeld, D.K.13
Fiedler, W.14
-
50
-
-
3342929538
-
DNA damage checkpoint kinase Chk2 triggers replicative senescence
-
Epub Jun 10, 2004
-
Gire V, Roux P, Wynford-Thomas D, Brondello JM, and Dulic V. DNA damage checkpoint kinase Chk2 triggers replicative senescence. EMBO J 23: 2554-2563, 2004. Epub Jun 10, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 2554-2563
-
-
Gire, V.1
Roux, P.2
Wynford-Thomas, D.3
Brondello, J.M.4
Dulic, V.5
-
51
-
-
0042734428
-
Oxidative stress and aging: Beyond correlation
-
Golden TR, Hinerfeld DA, and Melov S. Oxidative stress and aging: beyond correlation. Aging Cell 1: 117-123, 2002.
-
(2002)
Aging Cell
, vol.1
, pp. 117-123
-
-
Golden, T.R.1
Hinerfeld, D.A.2
Melov, S.3
-
52
-
-
0033863095
-
Endothelial cell dysfunction and nitric oxide synthase
-
Goligorsky MS. Endothelial cell dysfunction and nitric oxide synthase. Kidney Int 58: 1360-1376, 2000.
-
(2000)
Kidney Int
, vol.58
, pp. 1360-1376
-
-
Goligorsky, M.S.1
-
53
-
-
0037064011
-
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis
-
Epub Jul 24 2002
-
Gorbunova V, Seluanov A, and Pereira-Smith OM. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. J Biol Chem 277: 38540-38549, 2002. Epub Jul 24 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 38540-38549
-
-
Gorbunova, V.1
Seluanov, A.2
Pereira-Smith, O.M.3
-
54
-
-
19944433931
-
Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis
-
Epub Jan 10, 2005
-
Grisar J, Aletaha D, Steiner CW, Kapral T, Steiner S, Seidinger D, Weigel G, Schwarzinger I, Wolozcszuk W, Steiner G, and Smolen JS. Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis. Circulation 111: 204-211, 2005. Epub Jan 10, 2005.
-
(2005)
Circulation
, vol.111
, pp. 204-211
-
-
Grisar, J.1
Aletaha, D.2
Steiner, C.W.3
Kapral, T.4
Steiner, S.5
Seidinger, D.6
Weigel, G.7
Schwarzinger, I.8
Wolozcszuk, W.9
Steiner, G.10
Smolen, J.S.11
-
55
-
-
21744446394
-
Latest advances in antiaging medicine
-
Grossman T. Latest advances in antiaging medicine. Keio J Med 54: 85-94, 2005.
-
(2005)
Keio J Med
, vol.54
, pp. 85-94
-
-
Grossman, T.1
-
56
-
-
13944253348
-
Calorie restriction-the SIR2 connection
-
Guarente L and Picard F. Calorie restriction-the SIR2 connection. Cell 120: 473-482, 2005.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
57
-
-
13944255505
-
The future of aging therapies
-
Hadley EC, Lakatta EG, Morrison-Bogorad M, Warner HR, and Hodes RJ. The future of aging therapies. Cell 120: 557-567, 2005.
-
(2005)
Cell
, vol.120
, pp. 557-567
-
-
Hadley, E.C.1
Lakatta, E.G.2
Morrison-Bogorad, M.3
Warner, H.R.4
Hodes, R.J.5
-
58
-
-
9644310524
-
Differential regulation of apoptotic cell death in senescent human cells
-
Hampel B, Malisan F, Niederegger H, Testi R, and Jansen-Durr P. Differential regulation of apoptotic cell death in senescent human cells. Exp Gerontol 39: 1713-1721, 2004.
-
(2004)
Exp Gerontol
, vol.39
, pp. 1713-1721
-
-
Hampel, B.1
Malisan, F.2
Niederegger, H.3
Testi, R.4
Jansen-Durr, P.5
-
59
-
-
0038129710
-
Biology and plasticity of CD133+ hematopoietic stem cells
-
Handgretinger R, Gordon PR, Leimig T, Chen X, Buhring HJ, Niethammer D, and Kuci S. Biology and plasticity of CD133+ hematopoietic stem cells. Ann NY Acad Sci 996: 141-151, 2003.
-
(2003)
Ann NY Acad Sci
, vol.996
, pp. 141-151
-
-
Handgretinger, R.1
Gordon, P.R.2
Leimig, T.3
Chen, X.4
Buhring, H.J.5
Niethammer, D.6
Kuci, S.7
-
60
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, and Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460, 1990.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
61
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L and Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621, 1961.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
62
-
-
0034817423
-
Advanced glycation end products and the progressive course of renal disease
-
Heidland A, Sebekova K, and Schinzel R. Advanced glycation end products and the progressive course of renal disease. Am J Kidney Dis 38: S100-S106, 2001.
-
(2001)
Am J Kidney Dis
, vol.38
-
-
Heidland, A.1
Sebekova, K.2
Schinzel, R.3
-
63
-
-
18144377085
-
Impaired progenitor cell activity in age-related endothelial dysfunction
-
Heiss C, Keymel S, Niesler U, Ziemann J, Kelm M, and Kalka C. Impaired progenitor cell activity in age-related endothelial dysfunction. J Am Coll Cardiol 45: 1441-1448, 2005.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 1441-1448
-
-
Heiss, C.1
Keymel, S.2
Niesler, U.3
Ziemann, J.4
Kelm, M.5
Kalka, C.6
-
64
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
-
Herbig U, Jobling WA, Chen BP, Chen DJ, and Sedivy JM. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell 14: 501-513, 2004.
-
(2004)
Mol Cell
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
Chen, D.J.4
Sedivy, J.M.5
-
65
-
-
27844606594
-
Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells
-
Herbrig K, Haensel S, Oelschlaegel U, Pistrosch F, Foerster S, and Passauer J. Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells. Ann Rheum Dis 23: 23, 2005.
-
(2005)
Ann Rheum Dis
, vol.23
, pp. 23
-
-
Herbrig, K.1
Haensel, S.2
Oelschlaegel, U.3
Pistrosch, F.4
Foerster, S.5
Passauer, J.6
-
66
-
-
0037434561
-
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk
-
Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, and Finkel T. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 348: 593-600, 2003.
-
(2003)
N Engl J Med
, vol.348
, pp. 593-600
-
-
Hill, J.M.1
Zalos, G.2
Halcox, J.P.3
Schenke, W.H.4
Waclawiw, M.A.5
Quyyumi, A.A.6
Finkel, T.7
-
67
-
-
0035851216
-
Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: Important role of nitric oxide
-
Hoffmann J, Haendeler J, Aicher A, Rossig L, Vasa M, Zeiher AM, and Dimmeler S. Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide. Circ Res 89: 709-715, 2001.
-
(2001)
Circ Res
, vol.89
, pp. 709-715
-
-
Hoffmann, J.1
Haendeler, J.2
Aicher, A.3
Rossig, L.4
Vasa, M.5
Zeiher, A.M.6
Dimmeler, S.7
-
68
-
-
0031764553
-
Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM
-
Hofmann MA, Kohl B, Zumbach MS, Borcea V, Bierhaus A, Henkels M, Amiral J, Schmidt AM, Fiehn W, Ziegler R, Wahl P, and Nawroth PP. Hyperhomocyst(e) inemia and endothelial dysfunction in IDDM. Diabetes Care 21: 841-848, 1998.
-
(1998)
Diabetes Care
, vol.21
, pp. 841-848
-
-
Hofmann, M.A.1
Kohl, B.2
Zumbach, M.S.3
Borcea, V.4
Bierhaus, A.5
Henkels, M.6
Amiral, J.7
Schmidt, A.M.8
Fiehn, W.9
Ziegler, R.10
Wahl, P.11
Nawroth, P.P.12
-
69
-
-
32944463451
-
Circulating inflammatory endothelial cells contribute to endothelial progenitor cell dysfunction in patients with vasculitis and kidney involvement
-
Epub Aug 17, 2005
-
Holmen C, Elsheikh E, Stenvinkel P, Qureshi AR, Pettersson E, Jalkanen S, and Sumitran-Holgersson S. Circulating inflammatory endothelial cells contribute to endothelial progenitor cell dysfunction in patients with vasculitis and kidney involvement. J Am Soc Nephrol 16: 3110-3120, 2005. Epub Aug 17, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3110-3120
-
-
Holmen, C.1
Elsheikh, E.2
Stenvinkel, P.3
Qureshi, A.R.4
Pettersson, E.5
Jalkanen, S.6
Sumitran-Holgersson, S.7
-
70
-
-
0031453830
-
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy
-
Horie K, Miyata T, Maeda K, Miyata S, Sugiyama S, Sakai H, van Ypersole de Strihou C, Monnier VM, Witztum JL, and Kurokawa K. Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J Clin Invest 100: 2995-3004, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 2995-3004
-
-
Horie, K.1
Miyata, T.2
Maeda, K.3
Miyata, S.4
Sugiyama, S.5
Sakai, H.6
Van Ypersole De Strihou, C.7
Monnier, V.M.8
Witztum, J.L.9
Kurokawa, K.10
-
71
-
-
0031469636
-
Topographical association between the cyclin-dependent kinases inhibitor P21, p53 accumulation, and cellular proliferation in human atherosclerotic tissue
-
Ihling C, Menzel G, Wellens E, Monting JS, Schaefer HE, and Zeiher AM. Topographical association between the cyclin-dependent kinases inhibitor P21, p53 accumulation, and cellular proliferation in human atherosclerotic tissue. Arterioscler Thromb Vasc Biol 17: 2218-2224, 1997.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2218-2224
-
-
Ihling, C.1
Menzel, G.2
Wellens, E.3
Monting, J.S.4
Schaefer, H.E.5
Zeiher, A.M.6
-
72
-
-
12344256734
-
Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress
-
Imanishi T, Hano T, and Nishio I. Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress. J Hypertens 23: 97-104, 2005.
-
(2005)
J Hypertens
, vol.23
, pp. 97-104
-
-
Imanishi, T.1
Hano, T.2
Nishio, I.3
-
73
-
-
20444441960
-
Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells
-
Imanishi T, Hano T, and Nishio I. Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells. Hypertens Res 28: 263-271, 2005.
-
(2005)
Hypertens Res
, vol.28
, pp. 263-271
-
-
Imanishi, T.1
Hano, T.2
Nishio, I.3
-
74
-
-
3843063565
-
Oxidized low-density lipoprotein induces endothelial progenitor cell senescence, leading to cellular dysfunction
-
Imanishi T, Hano T, Sawamura T, and Nishio I. Oxidized low-density lipoprotein induces endothelial progenitor cell senescence, leading to cellular dysfunction. Clin Exp Pharmacol Physiol 31: 407-413, 2004.
-
(2004)
Clin Exp Pharmacol Physiol
, vol.31
, pp. 407-413
-
-
Imanishi, T.1
Hano, T.2
Sawamura, T.3
Nishio, I.4
-
75
-
-
29244453955
-
Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension
-
Imanishi T, Moriwaki C, Hano T, and Nishio I. Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension. J Hypertens 23: 1831-1837, 2005.
-
(2005)
J Hypertens
, vol.23
, pp. 1831-1837
-
-
Imanishi, T.1
Moriwaki, C.2
Hano, T.3
Nishio, I.4
-
76
-
-
1842789989
-
Mechanisms of cellular senescence in human and mouse cells
-
Itahana K, Campisi J, and Dimri GP. Mechanisms of cellular senescence in human and mouse cells. Biogerontology 5: 1-10, 2004.
-
(2004)
Biogerontology
, vol.5
, pp. 1-10
-
-
Itahana, K.1
Campisi, J.2
Dimri, G.P.3
-
77
-
-
0346157997
-
Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury
-
Epub Dec 3115, 2003
-
Iwakura A, Luedemann C, Shastry S, Hanley A, Kearney M, Aikawa R, Isner JM, Asahara T, and Losordo DW. Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury. Circulation 108: 3115-3121, 2003. Epub Dec 3115, 2003.
-
(2003)
Circulation
, vol.108
, pp. 3115-3121
-
-
Iwakura, A.1
Luedemann, C.2
Shastry, S.3
Hanley, A.4
Kearney, M.5
Aikawa, R.6
Isner, J.M.7
Asahara, T.8
Losordo, D.W.9
-
78
-
-
11144268164
-
Significant role for p16INK4a in p53-independent telomere-directed senescence
-
Jacobs JJ and de Lange T. Significant role for p16INK4a in p53-independent telomere-directed senescence. Curr Biol 14: 2302-2308, 2004.
-
(2004)
Curr Biol
, vol.14
, pp. 2302-2308
-
-
Jacobs, J.J.1
De Lange, T.2
-
79
-
-
0033564106
-
p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells
-
Jarrard DF, Sarkar S, Shi Y, Yeager TR, Magrane G, Kinoshita H, Nassif N, Meisner L, Newton MA, Waldman FM, and Reznikoff CA. p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells. Cancer Res 59: 2957-2964, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 2957-2964
-
-
Jarrard, D.F.1
Sarkar, S.2
Shi, Y.3
Yeager, T.R.4
Magrane, G.5
Kinoshita, H.6
Nassif, N.7
Meisner, L.8
Newton, M.A.9
Waldman, F.M.10
Reznikoff, C.A.11
-
80
-
-
0037019337
-
Pluripotency of mesenchymal stem cells derived from adult marrow
-
Epub Jun 2020, 2002
-
Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, and Verfaillie CM. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41-49, 2002. Epub Jun 2020, 2002.
-
(2002)
Nature
, vol.418
, pp. 41-49
-
-
Jiang, Y.1
Jahagirdar, B.N.2
Reinhardt, R.L.3
Schwartz, R.E.4
Keene, C.D.5
Ortiz-Gonzalez, X.R.6
Reyes, M.7
Lenvik, T.8
Lund, T.9
Blackstad, M.10
Du, J.11
Aldrich, S.12
Lisberg, A.13
Low, W.C.14
Largaespada, D.A.15
Verfaillie, C.M.16
-
81
-
-
0037378610
-
Telomere shortening and cellular senescence in a model of chronic renal allograft rejection
-
Joosten SA, van Ham V, Nolan CE, Borrias MC, Jardine AG, Shiels PG, van Kooten C, and Paul LC. Telomere shortening and cellular senescence in a model of chronic renal allograft rejection. Am J Pathol 162: 1305-1312, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 1305-1312
-
-
Joosten, S.A.1
Van Ham, V.2
Nolan, C.E.3
Borrias, M.C.4
Jardine, A.G.5
Shiels, P.G.6
Van Kooten, C.7
Paul, L.C.8
-
82
-
-
0035501411
-
Accumulation of oxidative DNA damage, 8-oxo-2′-deoxyguanosine, and change of repair systems during in vitro cellular aging of cultured human skin fibroblasts
-
Kaneko T, Tahara S, Taguchi T, and Kondo H. Accumulation of oxidative DNA damage, 8-oxo-2′-deoxyguanosine, and change of repair systems during in vitro cellular aging of cultured human skin fibroblasts. Mutat Res 487: 19-30, 2001.
-
(2001)
Mutat Res
, vol.487
, pp. 19-30
-
-
Kaneko, T.1
Tahara, S.2
Taguchi, T.3
Kondo, H.4
-
83
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 120: 449-460, 2005.
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
84
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, and Klingelhutz AJ. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396: 84-88, 1998.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
85
-
-
0035044085
-
Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
-
Kocher AA, Schuster MD, Szabolcs MJ, Takuma S, Burkhoff D, Wang J, Homma S, Edwards NM, and Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 7: 430-436, 2001.
-
(2001)
Nat Med
, vol.7
, pp. 430-436
-
-
Kocher, A.A.1
Schuster, M.D.2
Szabolcs, M.J.3
Takuma, S.4
Burkhoff, D.5
Wang, J.6
Homma, S.7
Edwards, N.M.8
Itescu, S.9
-
86
-
-
16244399236
-
Hyperglycemia reduces survival and impairs function of circulating blood-derived progenitor cells
-
Epub Jan 2020, 2005
-
Krankel N, Adams V, Linke A, Gielen S, Erbs S, Lenk K, Schuler G, and Hambrecht R. Hyperglycemia reduces survival and impairs function of circulating blood-derived progenitor cells. Arterioscler Thromb Vasc Biol 25: 698-703, 2005. Epub Jan 2020, 2005.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 698-703
-
-
Krankel, N.1
Adams, V.2
Linke, A.3
Gielen, S.4
Erbs, S.5
Lenk, K.6
Schuler, G.7
Hambrecht, R.8
-
87
-
-
0028924516
-
Increased p53 protein associated with aging in human diploid fibroblasts
-
Kulju KS and Lehman JM. Increased p53 protein associated with aging in human diploid fibroblasts. Exp Cell Res 217: 336-345, 1995.
-
(1995)
Exp Cell Res
, vol.217
, pp. 336-345
-
-
Kulju, K.S.1
Lehman, J.M.2
-
88
-
-
3042591085
-
Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells
-
Kurz DJ, Decary S, Hong Y, Trivier E, Akhmedov A, and Erusalimsky JD. Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. J Cell Sci 117: 2417-2426, 2004.
-
(2004)
J Cell Sci
, vol.117
, pp. 2417-2426
-
-
Kurz, D.J.1
Decary, S.2
Hong, Y.3
Trivier, E.4
Akhmedov, A.5
Erusalimsky, J.D.6
-
89
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM and Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869, 2001.
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
90
-
-
0030859290
-
Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress
-
Lander HM, Tauras JM, Ogiste JS, Hori O, Moss RA, and Schmidt AM. Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress. J Biol Chem 272: 17810-17814, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 17810-17814
-
-
Lander, H.M.1
Tauras, J.M.2
Ogiste, J.S.3
Hori, O.4
Moss, R.A.5
Schmidt, A.M.6
-
91
-
-
1642588198
-
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice
-
Lee CK, Pugh TD, Klopp RG, Edwards J, Allison DB, Weindruch R, and Prolla TA. The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice. Free Radic Biol Med 36: 1043-1057, 2004.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 1043-1057
-
-
Lee, C.K.1
Pugh, T.D.2
Klopp, R.G.3
Edwards, J.4
Allison, D.B.5
Weindruch, R.6
Prolla, T.A.7
-
92
-
-
0033591332
-
Improved inhibitors of glucosylceramide synthase
-
Lee L, Abe A, and Shayman JA. Improved inhibitors of glucosylceramide synthase. J Biol Chem 274: 14662-14669, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 14662-14669
-
-
Lee, L.1
Abe, A.2
Shayman, J.A.3
-
93
-
-
0032765047
-
Studies of the molecular mechanisms in the regulation of telomerase activity
-
Liu JP. Studies of the molecular mechanisms in the regulation of telomerase activity. FASEB J 13: 2091-2104, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 2091-2104
-
-
Liu, J.P.1
-
94
-
-
0042881052
-
The development and regulation of gene repair
-
Liu L, Parekh-Olmedo H, and Kmiec EB. The development and regulation of gene repair. Nat Rev Genet 4: 679-689, 2003.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 679-689
-
-
Liu, L.1
Parekh-Olmedo, H.2
Kmiec, E.B.3
-
95
-
-
9144271032
-
Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes
-
Loomans CJ, de Koning EJ, Staal FJ, Rookmaaker MB, Verseyden C, de Boer HC, Verhaar MC, Braam B, Rabelink TJ, and van Zonneveld AJ. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 53: 195-199, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 195-199
-
-
Loomans, C.J.1
De Koning, E.J.2
Staal, F.J.3
Rookmaaker, M.B.4
Verseyden, C.5
De Boer, H.C.6
Verhaar, M.C.7
Braam, B.8
Rabelink, T.J.9
Van Zonneveld, A.J.10
-
96
-
-
4744345878
-
c-Jun-deficient cells undergo premature senescence as a result of spontaneous DNA damage accumulation
-
MacLaren A, Black EJ, Clark W, and Gillespie DA. c-Jun-deficient cells undergo premature senescence as a result of spontaneous DNA damage accumulation. Mol Cell Biol 24: 9006-9018, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9006-9018
-
-
MacLaren, A.1
Black, E.J.2
Clark, W.3
Gillespie, D.A.4
-
97
-
-
0027194495
-
Senescence stimulates U937-endothelial cell interactions
-
Maier JA, Statuto M, and Ragnotti G. Senescence stimulates U937-endothelial cell interactions. Exp Cell Res 208: 270-274, 1993.
-
(1993)
Exp Cell Res
, vol.208
, pp. 270-274
-
-
Maier, J.A.1
Statuto, M.2
Ragnotti, G.3
-
99
-
-
0030566871
-
Kinetic study of the reaction of ebselen with peroxynitrite
-
Masumoto H, Kissner R, Koppenol WH, and Sies H. Kinetic study of the reaction of ebselen with peroxynitrite. FEBS Lett 398: 179-182, 1996.
-
(1996)
FEBS Lett
, vol.398
, pp. 179-182
-
-
Masumoto, H.1
Kissner, R.2
Koppenol, W.H.3
Sies, H.4
-
101
-
-
0035955754
-
eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization
-
Matsushita H, Chang E, Glassford AJ, Cooke JP, Chiu CP, and Tsao PS. eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization. Circ Res 89: 793-798, 2001.
-
(2001)
Circ Res
, vol.89
, pp. 793-798
-
-
Matsushita, H.1
Chang, E.2
Glassford, A.J.3
Cooke, J.P.4
Chiu, C.P.5
Tsao, P.S.6
-
102
-
-
0034233456
-
Emerging neuroprotective strategies for Alzheimer's disease: Dietary restriction, telomerase activation, and stem cell therapy
-
Mattson MP. Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy. Exp Gerontol 35: 489-502, 2000.
-
(2000)
Exp Gerontol
, vol.35
, pp. 489-502
-
-
Mattson, M.P.1
-
103
-
-
0038481271
-
Mitochondrial regulation of apoptosis
-
Mayer B and Oberbauer R. Mitochondrial regulation of apoptosis. News Physiol Sci 18: 89-94, 2003.
-
(2003)
News Physiol Sci
, vol.18
, pp. 89-94
-
-
Mayer, B.1
Oberbauer, R.2
-
104
-
-
0035141497
-
Cell senescence and its implications for nephrology
-
Melk A and Halloran PF. Cell senescence and its implications for nephrology. J Am Soc Nephrol 12: 385-393, 2001.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 385-393
-
-
Melk, A.1
Halloran, P.F.2
-
105
-
-
33646400775
-
Circulating endothelial progenitor cells from healthy smokers exhibit impaired functional activities
-
Michaud SE, Dussault S, Haddad P, Groleau J, and Rivard A. Circulating endothelial progenitor cells from healthy smokers exhibit impaired functional activities. Atherosclerosis 7: 7, 2005.
-
(2005)
Atherosclerosis
, vol.7
, pp. 7
-
-
Michaud, S.E.1
Dussault, S.2
Haddad, P.3
Groleau, J.4
Rivard, A.5
-
106
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, and Pelicci PG. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402: 309-313, 1999.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
107
-
-
0037007075
-
Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction
-
Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, and Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 105: 1541-1544, 2002.
-
(2002)
Circulation
, vol.105
, pp. 1541-1544
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Ishida, Y.4
Yoshida, H.5
Komuro, I.6
-
108
-
-
1042298050
-
Vascular cell senescence and vascular aging
-
Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, and Komuro I. Vascular cell senescence and vascular aging. J Mol Cell Cardiol 36: 175-183, 2004.
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 175-183
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Tateno, K.4
Kunieda, T.5
Komuro, I.6
-
109
-
-
26244466193
-
Promotion of cardiac regeneration by cardiac stem cells
-
Nagai T, Shiojima I, Matsuura K, and Komuro I. Promotion of cardiac regeneration by cardiac stem cells. Circ Res 97: 615-617, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 615-617
-
-
Nagai, T.1
Shiojima, I.2
Matsuura, K.3
Komuro, I.4
-
110
-
-
0346373567
-
Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts
-
Epub 2003 Oct 21
-
Naka K, Tachibana A, Ikeda K, and Motoyama N. Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts. J Biol Chem 279: 2030-2037, 2004. Epub 2003 Oct 21.
-
(2004)
J Biol Chem
, vol.279
, pp. 2030-2037
-
-
Naka, K.1
Tachibana, A.2
Ikeda, K.3
Motoyama, N.4
-
111
-
-
0030696009
-
Aging decreases the production of PGI2 in rat aortic endothelial cells
-
Nakajima M, Hashimoto M, Wang F, Yamanaga K, Nakamura N, Uchida T, and Yamanouchi K. Aging decreases the production of PGI2 in rat aortic endothelial cells. Exp Gerontol 32: 685-693, 1997.
-
(1997)
Exp Gerontol
, vol.32
, pp. 685-693
-
-
Nakajima, M.1
Hashimoto, M.2
Wang, F.3
Yamanaga, K.4
Nakamura, N.5
Uchida, T.6
Yamanouchi, K.7
-
112
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
Epub 2003 Feb 2115
-
Napoli C, Martin-Padura I, de Nigris F, Giorgio M, Mansueto G, Somma P, Condorelli M, Sica G, De Rosa G, and Pelicci P. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc Natl Acad Sci USA 100: 2112-2116, 2003. Epub 2003 Feb 2115.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
De Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.10
-
113
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, Lin AW, Hearn SA, Spector DL, Hannon GJ, and Lowe SW. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113: 703-716, 2003.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Lin, A.W.4
Hearn, S.A.5
Spector, D.L.6
Hannon, G.J.7
Lowe, S.W.8
-
114
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, and Brownlee M. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404: 787-790, 2000.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
Giardino, I.11
Brownlee, M.12
-
115
-
-
0029778901
-
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
-
Ogryzko VV, Hirai TH, Russanova VR, Barbie DA, and Howard BH. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol Cell Biol 16: 5210-5218, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5210-5218
-
-
Ogryzko, V.V.1
Hirai, T.H.2
Russanova, V.R.3
Barbie, D.A.4
Howard, B.H.5
-
116
-
-
17944371854
-
Mobilized bone marrow cells repair the infarcted heart, improving function and survival
-
Epub 2001 Aug 14
-
Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, and Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98: 10344-10349, 2001. Epub 2001 Aug 14.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10344-10349
-
-
Orlic, D.1
Kajstura, J.2
Chimenti, S.3
Limana, F.4
Jakoniuk, I.5
Quaini, F.6
Nadal-Ginard, B.7
Bodine, D.M.8
Leri, A.9
Anversa, P.10
-
117
-
-
0034980666
-
Induction of senescence by oncogenic Ras
-
Palmero I and Serrano M. Induction of senescence by oncogenic Ras. Methods Enzymol 333: 247-256, 2001.
-
(2001)
Methods Enzymol
, vol.333
, pp. 247-256
-
-
Palmero, I.1
Serrano, M.2
-
118
-
-
13944260728
-
Stromal-epithelial interactions in aging and cancer: Senescent fibroblasts alter epithelial cell differentiation
-
20056. Epub 2005 Jan 18
-
Parrinello S, Coppe JP, Krtolica A, and Campisi J. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci 118: 485-49, 20056. Epub 2005 Jan 18.
-
J Cell Sci
, vol.118
, pp. 485-549
-
-
Parrinello, S.1
Coppe, J.P.2
Krtolica, A.3
Campisi, J.4
-
119
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, and Campisi J. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol 5: 741-747, 2003.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
120
-
-
1842525838
-
Aging, anti-aging, and hormesis
-
Rattan SI. Aging, anti-aging, and hormesis. Mech Ageing Dev 125: 285-289, 2004.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 285-289
-
-
Rattan, S.I.1
-
121
-
-
0041592698
-
Aging, progenitor cell exhaustion, and atherosclerosis
-
Epub 2003 Jul 14
-
Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D, Ramaswami P, Pippen AM, Annex BH, Dong C, and Taylor DA. Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 108: 457-463, 2003. Epub 2003 Jul 14.
-
(2003)
Circulation
, vol.108
, pp. 457-463
-
-
Rauscher, F.M.1
Goldschmidt-Clermont, P.J.2
Davis, B.H.3
Wang, T.4
Gregg, D.5
Ramaswami, P.6
Pippen, A.M.7
Annex, B.H.8
Dong, C.9
Taylor, D.A.10
-
122
-
-
0038292179
-
Caspase inhibition switches doxorubicin-induced apoptosis to senescence
-
Rebbaa A, Zheng X, Chou PM, and Mirkin BL. Caspase inhibition switches doxorubicin-induced apoptosis to senescence. Oncogene 22: 2805-2811, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 2805-2811
-
-
Rebbaa, A.1
Zheng, X.2
Chou, P.M.3
Mirkin, B.L.4
-
123
-
-
0036171009
-
Origin of endothelial progenitors in human postnatal bone marrow
-
Reyes M, Dudek A, Jahagirdar B, Koodie L, Marker PH, and Verfaillie CM. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 109: 337-346, 2002.
-
(2002)
J Clin Invest
, vol.109
, pp. 337-346
-
-
Reyes, M.1
Dudek, A.2
Jahagirdar, B.3
Koodie, L.4
Marker, P.H.5
Verfaillie, C.M.6
-
124
-
-
0036407698
-
Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition
-
Rincheval V, Renaud F, Lemaire C, Godefroy N, Trotot P, Boulo V, Mignotte B, and Vayssiere JL. Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition. Biochem Biophys Res Commun 298: 282-288, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 282-288
-
-
Rincheval, V.1
Renaud, F.2
Lemaire, C.3
Godefroy, N.4
Trotot, P.5
Boulo, V.6
Mignotte, B.7
Vayssiere, J.L.8
-
125
-
-
0034939115
-
The role of oxidative stress in the onset and progression of diabetes and its complications: A summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society
-
Rosen P, Nawroth PP, King G, Moller W, Tritschler HJ, and Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab Res Rev 17: 189-212, 2001.
-
(2001)
Diabetes Metab Res Rev
, vol.17
, pp. 189-212
-
-
Rosen, P.1
Nawroth, P.P.2
King, G.3
Moller, W.4
Tritschler, H.J.5
Packer, L.6
-
126
-
-
24744452871
-
Youthful prospects for human stem-cell therapy. In another few decades, revised attitudes toward stem cells could lead to disease prevention and life extension
-
Rosenthal N. Youthful prospects for human stem-cell therapy. In another few decades, revised attitudes toward stem cells could lead to disease prevention and life extension. EMBO Rep 6: S30-S34, 2005.
-
(2005)
EMBO Rep
, vol.6
-
-
Rosenthal, N.1
-
127
-
-
12244254418
-
Telomerase, elixir of life for human cells?
-
Rufer N and Nabholz M. Telomerase, elixir of life for human cells? Med Sci 19: 345-350, 2003.
-
(2003)
Med Sci
, vol.19
, pp. 345-350
-
-
Rufer, N.1
Nabholz, M.2
-
128
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, and Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 14: 3037-3050, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
129
-
-
0027296739
-
Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell
-
Sato I, Morita I, Kaji K, Ikeda M, Nagao M, and Murota S. Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell. Biochem Biophys Res Commun 195: 1070-1076, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 1070-1076
-
-
Sato, I.1
Morita, I.2
Kaji, K.3
Ikeda, M.4
Nagao, M.5
Murota, S.6
-
130
-
-
0033857389
-
Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice
-
Schatteman GC, Hanlon HD, Jiao C, Dodds SG, and Christy BA. Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice. J Clin Invest 106: 571-578, 2000.
-
(2000)
J Clin Invest
, vol.106
, pp. 571-578
-
-
Schatteman, G.C.1
Hanlon, H.D.2
Jiao, C.3
Dodds, S.G.4
Christy, B.A.5
-
131
-
-
0035895774
-
Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions
-
Schmeisser A, Garlichs CD, Zhang H, Eskafi S, Graffy C, Ludwig J, Strasser RH, and Daniel WG. Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions. Cardiovasc Res 49: 671-680, 2001.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 671-680
-
-
Schmeisser, A.1
Garlichs, C.D.2
Zhang, H.3
Eskafi, S.4
Graffy, C.5
Ludwig, J.6
Strasser, R.H.7
Daniel, W.G.8
-
132
-
-
0344286498
-
Activation of receptor for advanced glycation end products: A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis
-
Schmidt AM, Yan SD, Wautier JL, and Stern D. Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 84: 489-497, 1999.
-
(1999)
Circ Res
, vol.84
, pp. 489-497
-
-
Schmidt, A.M.1
Yan, S.D.2
Wautier, J.L.3
Stern, D.4
-
133
-
-
0037013154
-
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
-
Schmitt CA, Fridman JS, Yang M, Lee S, Baranov E, Hoffman RM, and Lowe SW. A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell 109: 335-346, 2002.
-
(2002)
Cell
, vol.109
, pp. 335-346
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Lee, S.4
Baranov, E.5
Hoffman, R.M.6
Lowe, S.W.7
-
134
-
-
27144545010
-
Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes
-
Epub 2005 Jul 7
-
Schreurs MW, Hermsen MA, Geltink RI, Scholten KB, Brink AA, Kueter EW, Tijssen M, Meijer CJ, Ylstra B, Meijer GA, and Hooijberg E. Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes. Blood 106: 2663-2670, 2005. Epub 2005 Jul 7.
-
(2005)
Blood
, vol.106
, pp. 2663-2670
-
-
Schreurs, M.W.1
Hermsen, M.A.2
Geltink, R.I.3
Scholten, K.B.4
Brink, A.A.5
Kueter, E.W.6
Tijssen, M.7
Meijer, C.J.8
Ylstra, B.9
Meijer, G.A.10
Hooijberg, E.11
-
135
-
-
0035131153
-
Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53
-
Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, and Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Mol Cell Biol 21: 1552-1564, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1552-1564
-
-
Seluanov, A.1
Gorbunova, V.2
Falcovitz, A.3
Sigal, A.4
Milyavsky, M.5
Zurer, I.6
Shohat, G.7
Goldfinger, N.8
Rotter, V.9
-
137
-
-
0035817688
-
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
-
Sharpless NE, Bardeesy N, Lee KH, Carrasco D, Castrillon DH, Aguirre AJ, Wu EA, Horner JW, and DePinho RA. Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis. Nature 413: 86-91, 2001.
-
(2001)
Nature
, vol.413
, pp. 86-91
-
-
Sharpless, N.E.1
Bardeesy, N.2
Lee, K.H.3
Carrasco, D.4
Castrillon, D.H.5
Aguirre, A.J.6
Wu, E.A.7
Horner, J.W.8
DePinho, R.A.9
-
138
-
-
0033539169
-
Microarray analysis of replicative senescence
-
Shelton DN, Chang E, Whittier PS, Choi D, and Funk WD. Microarray analysis of replicative senescence. Curr Biol 9: 939-945, 1999.
-
(1999)
Curr Biol
, vol.9
, pp. 939-945
-
-
Shelton, D.N.1
Chang, E.2
Whittier, P.S.3
Choi, D.4
Funk, W.D.5
-
139
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS and Weindruch R. Oxidative stress, caloric restriction, and aging. Science 273: 59-63, 1996.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
140
-
-
8544236989
-
Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells
-
Epub 2004 Nov 31
-
Spyridopoulos I, Haendeler J, Urbich C, Brummendorf TH, Oh H, Schneider MD, Zeiher AM, and Dimmeler S. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation 110: 3136-3142, 2004. Epub 2004 Nov 31.
-
(2004)
Circulation
, vol.110
, pp. 3136-3142
-
-
Spyridopoulos, I.1
Haendeler, J.2
Urbich, C.3
Brummendorf, T.H.4
Oh, H.5
Schneider, M.D.6
Zeiher, A.M.7
Dimmeler, S.8
-
141
-
-
24344433191
-
Decrease and senescence of endothelial progenitor cells in patients with preeclampsia
-
Epub 2005 Jun 14
-
Sugawara J, Mitsui-Saito M, Hayashi C, Hoshiai T, Senoo M, Chisaka H, Yaegashi N, and Okamura K. Decrease and senescence of endothelial progenitor cells in patients with preeclampsia. J Clin Endocrinol Metab 90: 5329-5332, 2005. Epub 2005 Jun 14.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5329-5332
-
-
Sugawara, J.1
Mitsui-Saito, M.2
Hayashi, C.3
Hoshiai, T.4
Senoo, M.5
Chisaka, H.6
Yaegashi, N.7
Okamura, K.8
-
142
-
-
0037180517
-
Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
-
Tepper OM, Galiano RD, Capla JM, Kalka C, Gagne PJ, Jacobowitz GR, Levine JP, and Gurtner GC. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106: 2781-2786, 2002.
-
(2002)
Circulation
, vol.106
, pp. 2781-2786
-
-
Tepper, O.M.1
Galiano, R.D.2
Capla, J.M.3
Kalka, C.4
Gagne, P.J.5
Jacobowitz, G.R.6
Levine, J.P.7
Gurtner, G.C.8
-
143
-
-
0031984692
-
A phosphatidylinositol 3-kinase inhibitor induces a senescent-like growth arrest in human diploid fibroblasts
-
Tresini M, Mawal-Dewan M, Cristofalo VJ, and Sell C. A phosphatidylinositol 3-kinase inhibitor induces a senescent-like growth arrest in human diploid fibroblasts. Cancer Res 58: 1-4, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 1-4
-
-
Tresini, M.1
Mawal-Dewan, M.2
Cristofalo, V.J.3
Sell, C.4
-
144
-
-
0142248307
-
Senescence-associated cell death of human endothelial cells: The role of oxidative stress
-
Unterluggauer H, Hampel B, Zwerschke W, and Jansen-Durr P. Senescence-associated cell death of human endothelial cells: the role of oxidative stress. Exp Gerontol 38: 1149-1160, 2003.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1149-1160
-
-
Unterluggauer, H.1
Hampel, B.2
Zwerschke, W.3
Jansen-Durr, P.4
-
145
-
-
4143052506
-
Endothelial progenitor cells: Characterization and role in vascular biology
-
Urbich C and Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 95: 343-353, 2004.
-
(2004)
Circ Res
, vol.95
, pp. 343-353
-
-
Urbich, C.1
Dimmeler, S.2
-
146
-
-
0345688062
-
Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells
-
Epub 2003 Oct 27
-
Urbich C, Heeschen C, Aicher A, Dernbach E, Zeiher AM, and Dimmeler S. Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells. Circulation 108: 2511-2516, 2003. Epub 2003 Oct 27.
-
(2003)
Circulation
, vol.108
, pp. 2511-2516
-
-
Urbich, C.1
Heeschen, C.2
Aicher, A.3
Dernbach, E.4
Zeiher, A.M.5
Dimmeler, S.6
-
147
-
-
0034684652
-
Enhanced peroxynitrite formation is associated with vascular aging
-
van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, and Luscher TF. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 192: 1731-1744, 2000.
-
(2000)
J Exp Med
, vol.192
, pp. 1731-1744
-
-
Van Der Loo, B.1
Labugger, R.2
Skepper, J.N.3
Bachschmid, M.4
Kilo, J.5
Powell, J.M.6
Palacios-Callender, M.7
Erusalimsky, J.D.8
Quaschning, T.9
Malinski, T.10
Gygi, D.11
Ullrich, V.12
Luscher, T.F.13
-
148
-
-
17644433975
-
Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
-
Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, and Dimmeler S. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89: E1-E7, 2001.
-
(2001)
Circ Res
, vol.89
-
-
Vasa, M.1
Fichtlscherer, S.2
Aicher, A.3
Adler, K.4
Urbich, C.5
Martin, H.6
Zeiher, A.M.7
Dimmeler, S.8
-
149
-
-
0036323674
-
Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
-
Volonte D, Zhang K, Lisanti MP, and Galbiati F. Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts. Mol Biol Cell 13: 2502-2517, 2002.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2502-2517
-
-
Volonte, D.1
Zhang, K.2
Lisanti, M.P.3
Galbiati, F.4
-
150
-
-
0037148344
-
Telomerase as a universal tumor-associated antigen for cancer immunotherapy
-
Vonderheide RH. Telomerase as a universal tumor-associated antigen for cancer immunotherapy. Oncogene 21: 674-679, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 674-679
-
-
Vonderheide, R.H.1
-
151
-
-
0034894667
-
Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis
-
Wagner M, Hampel B, Bernhard D, Hala M, Zwerschke W, and Jansen-Durr P. Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis. Exp Gerontol 36: 1327-1347, 2001.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1327-1347
-
-
Wagner, M.1
Hampel, B.2
Bernhard, D.3
Hala, M.4
Zwerschke, W.5
Jansen-Durr, P.6
-
152
-
-
0036242247
-
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
-
Wang W, Chen JX, Liao R, Deng Q, Zhou JJ, Huang S, and Sun P. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol Cell Biol 22: 3389-3403, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3389-3403
-
-
Wang, W.1
Chen, J.X.2
Liao, R.3
Deng, Q.4
Zhou, J.J.5
Huang, S.6
Sun, P.7
-
153
-
-
0028102075
-
Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: A link between surface-associated AGEs and diabetic complications
-
Wautier JL, Wautier MP, Schmidt AM, Anderson GM, Hori O, Zoukourian C, Capron L, Chappey O, Yan SD, Brett J, Guillausseau PJ, and Stern D. Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications. Proc Natl Acad Sci USA 91: 7742-7746, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7742-7746
-
-
Wautier, J.L.1
Wautier, M.P.2
Schmidt, A.M.3
Anderson, G.M.4
Hori, O.5
Zoukourian, C.6
Capron, L.7
Chappey, O.8
Yan, S.D.9
Brett, J.10
Guillausseau, P.J.11
Stern, D.12
-
154
-
-
0037406905
-
Glucose, glycation, and RAGE: Implications for amplification of cellular dysfunction in diabetic nephropathy
-
Wendt T, Tanji N, Guo J, Hudson BI, Bierhaus A, Ramasamy R, Arnold B, Nawroth PP, Yan SF, D'Agati V, and Schmidt AM. Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy. J Am Soc Nephrol 14: 1383-1395, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1383-1395
-
-
Wendt, T.1
Tanji, N.2
Guo, J.3
Hudson, B.I.4
Bierhaus, A.5
Ramasamy, R.6
Arnold, B.7
Nawroth, P.P.8
Yan, S.F.9
D'Agati, V.10
Schmidt, A.M.11
-
155
-
-
24344442873
-
Circulating endothelial progenitor cells and cardiovascular outcomes
-
Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Bohm M, and Nickenig G. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353: 999-1007, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 999-1007
-
-
Werner, N.1
Kosiol, S.2
Schiegl, T.3
Ahlers, P.4
Walenta, K.5
Link, A.6
Bohm, M.7
Nickenig, G.8
-
156
-
-
0029962187
-
Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence
-
West MD, Shay JW, Wright WE, and Linskens MH. Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence. Exp Gerontol 31: 175-193, 1996.
-
(1996)
Exp Gerontol
, vol.31
, pp. 175-193
-
-
West, M.D.1
Shay, J.W.2
Wright, W.E.3
Linskens, M.H.4
-
157
-
-
0027194573
-
Advanced glycosylation end products: A new disease marker for diabetes and aging
-
Wu JT. Advanced glycosylation end products: a new disease marker for diabetes and aging. J Clin Lab Anal 7: 252-255, 1993.
-
(1993)
J Clin Lab Anal
, vol.7
, pp. 252-255
-
-
Wu, J.T.1
-
158
-
-
18844408655
-
Increased circulating endothelial progenitor cells in patients with bacterial pneumonia: Evidence that bone marrow derived cells contribute to lung repair
-
Yamada M, Kubo H, Ishizawa K, Kobayashi S, Shinkawa M, and Sasaki H. Increased circulating endothelial progenitor cells in patients with bacterial pneumonia: evidence that bone marrow derived cells contribute to lung repair. Thorax 60: 410-413, 2005.
-
(2005)
Thorax
, vol.60
, pp. 410-413
-
-
Yamada, M.1
Kubo, H.2
Ishizawa, K.3
Kobayashi, S.4
Shinkawa, M.5
Sasaki, H.6
-
159
-
-
0037197938
-
Lysosomal destabilization in p53-induced apoptosis
-
Epub 2002 Apr 16
-
Yuan XM, Li W, Dalen H, Lotem J, Kama R, Sachs L, and Brunk UT. Lysosomal destabilization in p53-induced apoptosis. Proc Natl Acad Sci USA 99: 6286-6291, 2002. Epub 2002 Apr 16.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6286-6291
-
-
Yuan, X.M.1
Li, W.2
Dalen, H.3
Lotem, J.4
Kama, R.5
Sachs, L.6
Brunk, U.T.7
-
160
-
-
0037452888
-
Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci
-
Epub 2003 Mar 7
-
Zhang H, Pan KH, and Cohen SN. Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci. Proc Natl Acad Sci USA 100: 3251-3256, 2003. Epub 2003 Mar 7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3251-3256
-
-
Zhang, H.1
Pan, K.H.2
Cohen, S.N.3
-
161
-
-
0037204535
-
Enhanced apoptosis in prolonged cultures of senescent porcine pulmonary artery endothelial cells
-
Zhang J, Patel JM, and Block ER. Enhanced apoptosis in prolonged cultures of senescent porcine pulmonary artery endothelial cells. Mech Ageing Dev 123: 613-625, 2002.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 613-625
-
-
Zhang, J.1
Patel, J.M.2
Block, E.R.3
-
162
-
-
0037155051
-
Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse
-
Zhang ZG, Zhang L, Jiang Q, and Chopp M. Bone marrow-derived endothelial
-
(2002)
Circ Res
, vol.90
, pp. 284-288
-
-
Zhang, Z.G.1
Zhang, L.2
Jiang, Q.3
Chopp, M.4
|