Caspase inhibition switches doxorubicin-induced apoptosis to senescence

Oncogene

Volumn 22, Issue 18, 2003, Pages 2805-2811

  Rebbaa, Abdelhadi ^a   Zheng, Xin ^a   Chou, Pauline M ^a   Mirkin, Bernard L ^a,b  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Apoptosis; Drug resistance; P21 WAF1; Senescence

Indexed keywords

BETA GALACTOSIDASE; CASPASE; CASPASE 3; CASPASE INHIBITOR; DOXORUBICIN; MOLECULAR MARKER; PROTEIN KINASE B; PROTEIN P21;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL DEATH; CELL PROTECTION; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG RESISTANCE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NECROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; BRAIN NEOPLASMS; CASPASES; CELL AGING; CELL DEATH; CYSTEINE PROTEINASE INHIBITORS; DOXORUBICIN; HUMANS; NEUROBLASTOMA; TUMOR CELLS, CULTURED;

EID: 0038292179     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206366     Document Type: Article

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