The impact of α-lipoic acid, coenzyme Q10, and caloric restriction on life span and gene expression patterns in mice

Free Radical Biology and Medicine

Volumn 36, Issue 8, 2004, Pages 1043-1057

  Lee, Cheol Koo ^a   Pugh, Thomas D ^b   Klopp, Roger G ^b   Edwards, Jode ^c   Allison, David B ^c   Weindruch, Richard ^b   Prolla, Tomas A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Lipoic acid; Aging; Ave; Average; Caloric restriction; CoA; Coenzyme A; Coenzyme Q10; CQ; CR; Double strand; Ds; FAO; Fatty acid oxidation; FC; Free radicals; Gene expression; Heart; Microarray

Indexed keywords

THIOCTIC ACID; UBIDECARENONE;

AGING; ANIMAL EXPERIMENT; ARTICLE; CALORIC RESTRICTION; CANCER INCIDENCE; CELL STRUCTURE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DNA MICROARRAY; ENERGY METABOLISM; EXTRACELLULAR MATRIX; GENE EXPRESSION; HEART; LIFESPAN; LONGEVITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN METABOLISM;

ALGORITHMS; ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CALORIC RESTRICTION; COMPLEMENT SYSTEM PROTEINS; CYTOSOL; DIETARY SUPPLEMENTS; EXTRACELLULAR MATRIX; FREE RADICALS; GENE EXPRESSION REGULATION; LONGEVITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDES; OXIDATIVE STRESS; OXYGEN; PHOSPHORYLATION; RNA; THIOCTIC ACID; TIME FACTORS; TRANSCRIPTION, GENETIC; UBIQUINONE;

EID: 1642588198     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.01.015     Document Type: Article

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