-
1
-
-
0002762599
-
Sclerose des cordons lateraux de la moelle epiniere chez une femme hysterique atteinte de contracture permanente des quatre membres
-
Charcot J.M. Sclerose des cordons lateraux de la moelle epiniere chez une femme hysterique atteinte de contracture permanente des quatre membres. Bull Soc Med Hopit Paris (1865) 24-35
-
(1865)
Bull Soc Med Hopit Paris
, pp. 24-35
-
-
Charcot, J.M.1
-
3
-
-
0028142392
-
El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors
-
Brooks B.R. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci 124 suppl (1994) 96-107
-
(1994)
J Neurol Sci
, vol.124
, Issue.SUPPL
, pp. 96-107
-
-
Brooks, B.R.1
-
4
-
-
0032716522
-
Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology Committee on Research
-
Miller R.G., Munsat T.L., Swash M., and Brooks B.R. Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology Committee on Research. J Neurol Sci 169 (1999) 2-12
-
(1999)
J Neurol Sci
, vol.169
, pp. 2-12
-
-
Miller, R.G.1
Munsat, T.L.2
Swash, M.3
Brooks, B.R.4
-
5
-
-
0001181734
-
Airlie House guidelines. Therapeutic trials in amyotrophic lateral sclerosis. Airlie House "Therapeutic Trials in ALS" Workshop Contributors
-
World Federation of Neurology Research Group on Neuromuscular Diseases Subcommittee on Motor Neuron Disease
-
World Federation of Neurology Research Group on Neuromuscular Diseases Subcommittee on Motor Neuron Disease. Airlie House guidelines. Therapeutic trials in amyotrophic lateral sclerosis. Airlie House "Therapeutic Trials in ALS" Workshop Contributors. J Neurol Sci 129 suppl (1995) 1-10
-
(1995)
J Neurol Sci
, vol.129
, Issue.SUPPL
, pp. 1-10
-
-
-
6
-
-
0002727357
-
-
World Federation of Neurology, London, UK Available at: www.wfnals.org/guidelines/1998elescorial/elescorial1998.htm.
-
Brooks B.R., Miller R.G., Swash M., and Munsat T.L. El Escorial Revisited: Revised Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis (1998), World Federation of Neurology, London, UK. http://www.wfnals.org/guidelines/1998elescorial/elescorial1998.htm Available at: www.wfnals.org/guidelines/1998elescorial/elescorial1998.htm.
-
(1998)
El Escorial Revisited: Revised Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis
-
-
Brooks, B.R.1
Miller, R.G.2
Swash, M.3
Munsat, T.L.4
-
8
-
-
0032692481
-
The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III)
-
Cedarbaum J.M., Stambler N., Malta E., et al. The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci 169 (1999) 13-21
-
(1999)
J Neurol Sci
, vol.169
, pp. 13-21
-
-
Cedarbaum, J.M.1
Stambler, N.2
Malta, E.3
-
10
-
-
0001834969
-
Positron emission tomography (PET)-its potential to provide surrogate markers in ALS
-
Turner M.R., and Leigh P.N. Positron emission tomography (PET)-its potential to provide surrogate markers in ALS. Amyotroph Lateral Scler Other Motor Neuron Disord 1 suppl 2 (2000) S17-S22
-
(2000)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, Issue.SUPPL. 2
-
-
Turner, M.R.1
Leigh, P.N.2
-
11
-
-
0029144351
-
Motor neuron disease. Studies of the corticospinal excitation of single motor neurons by magnetic brain stimulation
-
Mills K.R. Motor neuron disease. Studies of the corticospinal excitation of single motor neurons by magnetic brain stimulation. Brain 118 pt 4 (1995) 971-982
-
(1995)
Brain
, vol.118
, Issue.PART 4
, pp. 971-982
-
-
Mills, K.R.1
-
13
-
-
0029999423
-
A new short form individual quality of life measure (SEIQoL-DW): application in a cohort of individuals with HIV/AIDS
-
Hickey A.M., Bury G., O'Boyle C.A., et al. A new short form individual quality of life measure (SEIQoL-DW): application in a cohort of individuals with HIV/AIDS. BMJ 313 (1996) 29-33
-
(1996)
BMJ
, vol.313
, pp. 29-33
-
-
Hickey, A.M.1
Bury, G.2
O'Boyle, C.A.3
-
14
-
-
0019827980
-
The Sickness Impact Profile: development and final revision of a health status measure
-
Bergner M., Bobbitt R.A., Carter W.B., and Gilson B.S. The Sickness Impact Profile: development and final revision of a health status measure. Med Care 19 (1981) 787-805
-
(1981)
Med Care
, vol.19
, pp. 787-805
-
-
Bergner, M.1
Bobbitt, R.A.2
Carter, W.B.3
Gilson, B.S.4
-
15
-
-
0022652901
-
Quantitative motor assessment in amyotrophic lateral sclerosis
-
Andres P.L., Hedlund W., Finison L., et al. Quantitative motor assessment in amyotrophic lateral sclerosis. Neurology 36 (1986) 937-941
-
(1986)
Neurology
, vol.36
, pp. 937-941
-
-
Andres, P.L.1
Hedlund, W.2
Finison, L.3
-
16
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II
-
Lacomblez L., Bensimon G., Leigh P.N., et al. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 347 (1996) 1425-1431
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
-
17
-
-
0030016827
-
Riluzole and amyotrophic lateral sclerosis
-
Guiloff R.J., Goonetilleke A., and Emami J. Riluzole and amyotrophic lateral sclerosis. Lancet 348 (1996) 336-337
-
(1996)
Lancet
, vol.348
, pp. 336-337
-
-
Guiloff, R.J.1
Goonetilleke, A.2
Emami, J.3
-
19
-
-
0029004147
-
Respiratory assistance with a non-invasive ventilator (BiPAP) in MND/ALS patients: survival rates in a controlled trial
-
Pinto A.C., Evangelista T., Carvalho M., et al. Respiratory assistance with a non-invasive ventilator (BiPAP) in MND/ALS patients: survival rates in a controlled trial. J Neurol Sci 129 suppl (1995) 19-26
-
(1995)
J Neurol Sci
, vol.129
, Issue.SUPPL
, pp. 19-26
-
-
Pinto, A.C.1
Evangelista, T.2
Carvalho, M.3
-
20
-
-
0035119438
-
Objective measures of the efficacy of noninvasive positive-pressure ventilation in amyotrophic lateral sclerosis
-
Aboussouan L.S., Khan S.U., Banerjee M., et al. Objective measures of the efficacy of noninvasive positive-pressure ventilation in amyotrophic lateral sclerosis. Muscle Nerve 24 (2001) 403-409
-
(2001)
Muscle Nerve
, vol.24
, pp. 403-409
-
-
Aboussouan, L.S.1
Khan, S.U.2
Banerjee, M.3
-
21
-
-
0034784364
-
Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis
-
Lyall R.A., Donaldson N., Polkey M.I., et al. Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis. Brain 124 pt 10 (2001) 2000-2013
-
(2001)
Brain
, vol.124
, Issue.PART 10
, pp. 2000-2013
-
-
Lyall, R.A.1
Donaldson, N.2
Polkey, M.I.3
-
22
-
-
0033486693
-
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
-
Armon C. How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?. ALS and other motor neuron disorders 1 (1999) 3-14
-
(1999)
ALS and other motor neuron disorders
, vol.1
, pp. 3-14
-
-
Armon, C.1
-
23
-
-
0002743463
-
Motor Neurone Disease: Basic Designs, Sample Sizes and Pitfalls.
-
Guiloff R.J. (Ed), Springer, New York
-
Brooks B.R., Sanjak M., Belden D., and Waclawik A. Motor Neurone Disease: Basic Designs, Sample Sizes and Pitfalls. In: Guiloff R.J. (Ed). Clinical Trials in Neurology (2001), Springer, New York 427-450
-
(2001)
Clinical Trials in Neurology
, pp. 427-450
-
-
Brooks, B.R.1
Sanjak, M.2
Belden, D.3
Waclawik, A.4
-
26
-
-
0023860093
-
Use of composite scores (megascores) to measure deficit in amyotrophic lateral sclerosis
-
Andres P.L., Finison L.J., Conlon T., et al. Use of composite scores (megascores) to measure deficit in amyotrophic lateral sclerosis. Neurology 38 (1988) 405-408
-
(1988)
Neurology
, vol.38
, pp. 405-408
-
-
Andres, P.L.1
Finison, L.J.2
Conlon, T.3
-
27
-
-
0029829076
-
A comparison of three measures of disease progression in ALS
-
Andres P.L., Skerry L.M., Thornell B., et al. A comparison of three measures of disease progression in ALS. J Neurol Sci 139 suppl (1996) 64-70
-
(1996)
J Neurol Sci
, vol.139
, Issue.SUPPL
, pp. 64-70
-
-
Andres, P.L.1
Skerry, L.M.2
Thornell, B.3
-
28
-
-
0029037348
-
Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction
-
Haverkamp L.J., Appel V., and Appel S.H. Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction. Brain 118 pt 3 (1995) 707-719
-
(1995)
Brain
, vol.118
, Issue.PART 3
, pp. 707-719
-
-
Haverkamp, L.J.1
Appel, V.2
Appel, S.H.3
-
29
-
-
0035846617
-
Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS
-
Bourke S.C., Shaw P.J., and Gibson G.J. Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS. Neurology 57 (2001) 2040-2044
-
(2001)
Neurology
, vol.57
, pp. 2040-2044
-
-
Bourke, S.C.1
Shaw, P.J.2
Gibson, G.J.3
-
30
-
-
0035838372
-
A prospective study of quality of life in ALS patients treated with noninvasive ventilation
-
Lyall R.A., Donaldson N., Fleming T., et al. A prospective study of quality of life in ALS patients treated with noninvasive ventilation. Neurology 57 (2001) 153-156
-
(2001)
Neurology
, vol.57
, pp. 153-156
-
-
Lyall, R.A.1
Donaldson, N.2
Fleming, T.3
-
31
-
-
0032709463
-
Sniff nasal pressure: a sensitive respiratory test to assess progression of amyotrophic lateral sclerosis
-
Fitting J.W., Paillex R., Hirt L., et al. Sniff nasal pressure: a sensitive respiratory test to assess progression of amyotrophic lateral sclerosis. Ann Neurol 46 (1999) 887-893
-
(1999)
Ann Neurol
, vol.46
, pp. 887-893
-
-
Fitting, J.W.1
Paillex, R.2
Hirt, L.3
-
32
-
-
0016251677
-
The administration of guanidine in amyotrophic lateral sclerosis
-
Norris Jr. F.H., Calanchini P.R., Fallat R.J., et al. The administration of guanidine in amyotrophic lateral sclerosis. Neurology 24 (1974) 721-728
-
(1974)
Neurology
, vol.24
, pp. 721-728
-
-
Norris Jr., F.H.1
Calanchini, P.R.2
Fallat, R.J.3
-
33
-
-
0023195073
-
A rating scale for amyotrophic lateral sclerosis: description and preliminary experience
-
Appel V., Stewart S.S., Smith G., and Appel S.H. A rating scale for amyotrophic lateral sclerosis: description and preliminary experience. Ann Neurol 22 (1987) 328-333
-
(1987)
Ann Neurol
, vol.22
, pp. 328-333
-
-
Appel, V.1
Stewart, S.S.2
Smith, G.3
Appel, S.H.4
-
34
-
-
6844266272
-
Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group
-
Lai E.C., Felice K.J., Festoff B.W., et al. Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group. Neurology 49 (1997) 1621-1630
-
(1997)
Neurology
, vol.49
, pp. 1621-1630
-
-
Lai, E.C.1
Felice, K.J.2
Festoff, B.W.3
-
35
-
-
0031722582
-
A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group
-
Borasio G.D., Robberecht W., Leigh P.N., et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group. Neurology 51 (1998) 583-586
-
(1998)
Neurology
, vol.51
, pp. 583-586
-
-
Borasio, G.D.1
Robberecht, W.2
Leigh, P.N.3
-
36
-
-
0001163277
-
The Amyotrophic Lateral Sclerosis Functional Rating Scale. Assessment of activities of daily living in patients with amyotrophic lateral sclerosis. The ALS CNTF treatment study (ACTS) phase I-II Study Group
-
The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group
-
The ALS CNTF Treatment Study (ACTS) Phase I-II Study Group. The Amyotrophic Lateral Sclerosis Functional Rating Scale. Assessment of activities of daily living in patients with amyotrophic lateral sclerosis. The ALS CNTF treatment study (ACTS) phase I-II Study Group. Arch Neurol 53 (1996) 141-147
-
(1996)
Arch Neurol
, vol.53
, pp. 141-147
-
-
-
37
-
-
0001209945
-
Review of Clinical Trials
-
Meininger V., Swash M., and Brown Jr. R.H. (Eds), Martin Dunitz, London
-
Meininger V., and Salachas F. Review of Clinical Trials. In: Meininger V., Swash M., and Brown Jr. R.H. (Eds). Amyotrophic Lateral Sclerosis (2000), Martin Dunitz, London 389-402
-
(2000)
Amyotrophic Lateral Sclerosis
, pp. 389-402
-
-
Meininger, V.1
Salachas, F.2
-
38
-
-
0036210968
-
The diagnostic interval in amyotrophic lateral sclerosis
-
Iwasaki Y., Ikeda K., Ichikawa Y., et al. The diagnostic interval in amyotrophic lateral sclerosis. Clin Neurol Neurosurg 104 (2002) 87-89
-
(2002)
Clin Neurol Neurosurg
, vol.104
, pp. 87-89
-
-
Iwasaki, Y.1
Ikeda, K.2
Ichikawa, Y.3
-
39
-
-
0037168769
-
Early symptom progression rate is related to ALS outcome: a prospective population-based study
-
Turner M., and Al Chalabi A. Early symptom progression rate is related to ALS outcome: a prospective population-based study. Neurology 59 (2002) 2012-2013
-
(2002)
Neurology
, vol.59
, pp. 2012-2013
-
-
Turner, M.1
Al Chalabi, A.2
-
41
-
-
0033837958
-
Quality of life in ALS depends on factors other than strength and physical function
-
Simmons Z., Bremer B.A., Robbins R.A., et al. Quality of life in ALS depends on factors other than strength and physical function. Neurology 55 (2000) 388-392
-
(2000)
Neurology
, vol.55
, pp. 388-392
-
-
Simmons, Z.1
Bremer, B.A.2
Robbins, R.A.3
-
42
-
-
0033675585
-
The ALS Health Profile Study: quality of life of amyotrophic lateral sclerosis patients and carers in Europe
-
Jenkinson C., Fitzpatrick R., Swash M., and Peto V. The ALS Health Profile Study: quality of life of amyotrophic lateral sclerosis patients and carers in Europe. J Neurol 247 (2000) 835-840
-
(2000)
J Neurol
, vol.247
, pp. 835-840
-
-
Jenkinson, C.1
Fitzpatrick, R.2
Swash, M.3
Peto, V.4
-
44
-
-
0001531983
-
Rehabilitation Outcome Measures
-
Herndon R.M. (Ed), Demos Vermande, New York
-
Coulthard-Morris L., Burks J.S., and Herndon R.M. Rehabilitation Outcome Measures. In: Herndon R.M. (Ed). Handbook of Neurologic Rating Scales (1997), Demos Vermande, New York 225-264
-
(1997)
Handbook of Neurologic Rating Scales
, pp. 225-264
-
-
Coulthard-Morris, L.1
Burks, J.S.2
Herndon, R.M.3
-
45
-
-
0035886617
-
Patients' assessment of quality of life instruments: a randomized study of SIP, SF-36 and SEIQoL-DW in patients with amyotrophic lateral sclerosis
-
Neudert C., Wasner M., and Borasio G.D. Patients' assessment of quality of life instruments: a randomized study of SIP, SF-36 and SEIQoL-DW in patients with amyotrophic lateral sclerosis. J Neurol Sci 191 (2001) 103-109
-
(2001)
J Neurol Sci
, vol.191
, pp. 103-109
-
-
Neudert, C.1
Wasner, M.2
Borasio, G.D.3
-
46
-
-
0035023053
-
Assessing health status quality of life in ALS: comparison of the SIP/ALS-19 with the ALS Functional Rating Scale and the Short Form-12 Health Survey. ALS C.A.R.E. Study Group. Clinical Assessement, Research, and Education
-
Bromberg M.B., Anderson F., Davidson M., and Miller R.G. Assessing health status quality of life in ALS: comparison of the SIP/ALS-19 with the ALS Functional Rating Scale and the Short Form-12 Health Survey. ALS C.A.R.E. Study Group. Clinical Assessement, Research, and Education. Amyotroph Lateral Scler Other Motor Neuron Disord 2 (2001) 31-37
-
(2001)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.2
, pp. 31-37
-
-
Bromberg, M.B.1
Anderson, F.2
Davidson, M.3
Miller, R.G.4
-
47
-
-
0030014596
-
Relationship of the Tufts Quantitative Neuromuscular Exam (TQNE) and the Sickness Impact Profile (SIP) in measuring progression of ALS. SSNJV/CNTF ALS Study Group
-
McGuire D., Garrison L., Armon C., et al. Relationship of the Tufts Quantitative Neuromuscular Exam (TQNE) and the Sickness Impact Profile (SIP) in measuring progression of ALS. SSNJV/CNTF ALS Study Group. Neurology 46 (1996) 1442-1444
-
(1996)
Neurology
, vol.46
, pp. 1442-1444
-
-
McGuire, D.1
Garrison, L.2
Armon, C.3
-
48
-
-
0030666284
-
A brief quality-of-life measure for ALS clinical trials based on a subset of items from the sickness impact profile. The Syntex-Synergen ALS/CNTF Study Group
-
McGuire D., Garrison L., Armon C., et al. A brief quality-of-life measure for ALS clinical trials based on a subset of items from the sickness impact profile. The Syntex-Synergen ALS/CNTF Study Group. J Neurol Sci 152 suppl 1 (1997) S18-S22
-
(1997)
J Neurol Sci
, vol.152
, Issue.SUPPL. 1
-
-
McGuire, D.1
Garrison, L.2
Armon, C.3
-
49
-
-
0032731938
-
Development and validation of a short measure of health status for individuals with amyotrophic lateral sclerosis/motor neurone disease: the ALSAQ-40
-
Jenkinson C., Fitzpatrick R., Brennan C., et al. Development and validation of a short measure of health status for individuals with amyotrophic lateral sclerosis/motor neurone disease: the ALSAQ-40. J Neurol 246 suppl 3 (1999) III16-III21
-
(1999)
J Neurol
, vol.246
, Issue.SUPPL. 3
-
-
Jenkinson, C.1
Fitzpatrick, R.2
Brennan, C.3
-
51
-
-
0034326807
-
The amyotrophic lateral sclerosis assessment questionnaire (ALSAQ-40): tests of data quality, score reliability and response rate in a survey of patients
-
Jenkinson C., Levvy G., Fitzpatrick R., and Garratt A. The amyotrophic lateral sclerosis assessment questionnaire (ALSAQ-40): tests of data quality, score reliability and response rate in a survey of patients. J Neurol Sci 180 (2000) 94-100
-
(2000)
J Neurol Sci
, vol.180
, pp. 94-100
-
-
Jenkinson, C.1
Levvy, G.2
Fitzpatrick, R.3
Garratt, A.4
-
52
-
-
0035133668
-
Reduced item set for the amyotrophic lateral sclerosis assessment questionnaire: development and validation of the ALSAQ-5
-
Jenkinson C., and Fitzpatrick R. Reduced item set for the amyotrophic lateral sclerosis assessment questionnaire: development and validation of the ALSAQ-5. J Neurol Neurosurg Psychiatry 70 (2001) 70-73
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.70
, pp. 70-73
-
-
Jenkinson, C.1
Fitzpatrick, R.2
-
53
-
-
0037154132
-
Comparison of instruments addressing quality of life in patients with ALS and their caregivers
-
Bromberg M.B., and Forshew D.A. Comparison of instruments addressing quality of life in patients with ALS and their caregivers. Neurology 58 (2002) 320-322
-
(2002)
Neurology
, vol.58
, pp. 320-322
-
-
Bromberg, M.B.1
Forshew, D.A.2
-
54
-
-
0033856830
-
Recent advances in amyotrophic lateral sclerosis
-
Al-Chalabi A., and Leigh P.N. Recent advances in amyotrophic lateral sclerosis. Curr Opin Neurol 13 (2000) 397-405
-
(2000)
Curr Opin Neurol
, vol.13
, pp. 397-405
-
-
Al-Chalabi, A.1
Leigh, P.N.2
-
55
-
-
0035240305
-
Progress in the pathogenesis of amyotrophic lateral sclerosis
-
Shaw C.E., Al Chalabi A., and Leigh N. Progress in the pathogenesis of amyotrophic lateral sclerosis. Curr Neurol Neurosci Rep 1 (2001) 69-76
-
(2001)
Curr Neurol Neurosci Rep
, vol.1
, pp. 69-76
-
-
Shaw, C.E.1
Al Chalabi, A.2
Leigh, N.3
-
56
-
-
0035978743
-
Amyotrophic lateral sclerosis
-
Rowland L.P., and Shneider N.A. Amyotrophic lateral sclerosis. N Engl J Med 344 (2001) 1688-1700
-
(2001)
N Engl J Med
, vol.344
, pp. 1688-1700
-
-
Rowland, L.P.1
Shneider, N.A.2
-
57
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
Cleveland D.W., and Rothstein J.D. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2 (2001) 806-819
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
58
-
-
0036605466
-
Therapies in amyotrophic lateral sclerosis-beyond riluzole
-
Morrison K.E. Therapies in amyotrophic lateral sclerosis-beyond riluzole. Curr Opin Pharmacol 2 (2002) 302-309
-
(2002)
Curr Opin Pharmacol
, vol.2
, pp. 302-309
-
-
Morrison, K.E.1
-
59
-
-
0032967382
-
The role of excitotoxicity in neurodegenerative disease: implications for therapy
-
Doble A. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther 81 (1999) 163-221
-
(1999)
Pharmacol Ther
, vol.81
, pp. 163-221
-
-
Doble, A.1
-
60
-
-
0029732866
-
Excitotoxicity in ALS
-
Leigh P.N., and Meldrum B.S. Excitotoxicity in ALS. Neurology 47 6, suppl 4 (1996) S221-S227
-
(1996)
Neurology
, vol.47
, Issue.6 SUPPL. 4
-
-
Leigh, P.N.1
Meldrum, B.S.2
-
61
-
-
0036787803
-
Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
-
Heath P.R., and Shaw P.J. Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis. Muscle Nerve 26 (2002) 438-458
-
(2002)
Muscle Nerve
, vol.26
, pp. 438-458
-
-
Heath, P.R.1
Shaw, P.J.2
-
62
-
-
0023617392
-
Abnormal glutamate metabolism in amyotrophic lateral sclerosis
-
Plaitakis A., and Caroscio J.T. Abnormal glutamate metabolism in amyotrophic lateral sclerosis. Ann Neurol 22 (1987) 575-579
-
(1987)
Ann Neurol
, vol.22
, pp. 575-579
-
-
Plaitakis, A.1
Caroscio, J.T.2
-
63
-
-
0025299819
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
-
Rothstein J.D., Tsai G., Kuncl R.W., et al. Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Ann Neurol 28 (1990) 18-25
-
(1990)
Ann Neurol
, vol.28
, pp. 18-25
-
-
Rothstein, J.D.1
Tsai, G.2
Kuncl, R.W.3
-
64
-
-
0029067210
-
CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients
-
Shaw P.J., Forrest V., Ince P.G., et al. CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients. Neurodegeneration 4 (1995) 209-216
-
(1995)
Neurodegeneration
, vol.4
, pp. 209-216
-
-
Shaw, P.J.1
Forrest, V.2
Ince, P.G.3
-
65
-
-
0037081113
-
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients
-
Spreux-Varoquaux O., Bensimon G., Lacomblez L., et al. Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients. J Neurol Sci 193 (2002) 73-78
-
(2002)
J Neurol Sci
, vol.193
, pp. 73-78
-
-
Spreux-Varoquaux, O.1
Bensimon, G.2
Lacomblez, L.3
-
66
-
-
0035105962
-
Glutamate transporters in neurologic disease
-
Maragakis N.J., and Rothstein J.D. Glutamate transporters in neurologic disease. Arch Neurol 58 (2001) 365-370
-
(2001)
Arch Neurol
, vol.58
, pp. 365-370
-
-
Maragakis, N.J.1
Rothstein, J.D.2
-
67
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
Rothstein J.D., Van Kammen M., Levey A.I., et al. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38 (1995) 73-84
-
(1995)
Ann Neurol
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
-
68
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
Howland D.S., Liu J., She Y., et al. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci USA 99 (2002) 1604-1609
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
-
69
-
-
0032032013
-
Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
-
Lin C.L., Bristol L.A., Jin L., et al. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron 20 (1998) 589-602
-
(1998)
Neuron
, vol.20
, pp. 589-602
-
-
Lin, C.L.1
Bristol, L.A.2
Jin, L.3
-
70
-
-
0032716796
-
The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals
-
Meyer T., Fromm A., Munch C., et al. The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals. J Neurol Sci 170 (1999) 45-50
-
(1999)
J Neurol Sci
, vol.170
, pp. 45-50
-
-
Meyer, T.1
Fromm, A.2
Munch, C.3
-
71
-
-
0035020941
-
Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis
-
Flowers J.M., Powell J.F., Leigh P.N., et al. Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis. Ann Neurol 49 (2001) 643-649
-
(2001)
Ann Neurol
, vol.49
, pp. 643-649
-
-
Flowers, J.M.1
Powell, J.F.2
Leigh, P.N.3
-
73
-
-
0023913736
-
Pilot trial of branched-chain aminoacids in amyotrophic lateral sclerosis
-
Plaitakis A., Smith J., Mandeli J., and Yahr M.D. Pilot trial of branched-chain aminoacids in amyotrophic lateral sclerosis. Lancet 1 (1988) 1015-1018
-
(1988)
Lancet
, vol.1
, pp. 1015-1018
-
-
Plaitakis, A.1
Smith, J.2
Mandeli, J.3
Yahr, M.D.4
-
74
-
-
0024826532
-
Branched-chain amino acids in the treatment of amyotrophic lateral sclerosis
-
Testa D., Caraceni T., and Fetoni V. Branched-chain amino acids in the treatment of amyotrophic lateral sclerosis. J Neurol 236 (1989) 445-447
-
(1989)
J Neurol
, vol.236
, pp. 445-447
-
-
Testa, D.1
Caraceni, T.2
Fetoni, V.3
-
75
-
-
0027064893
-
A double-blind placebo-controlled study of branched chain amino acids and l-threonine for the short-term treatment of signs and symptoms of amyotrophic lateral sclerosis
-
Gil R., Neau J.P., et al. A double-blind placebo-controlled study of branched chain amino acids and l-threonine for the short-term treatment of signs and symptoms of amyotrophic lateral sclerosis. La Semaine des Hôpitaux (Paris) 68 (1992) 1472-1475
-
(1992)
La Semaine des Hôpitaux (Paris)
, vol.68
, pp. 1472-1475
-
-
Gil, R.1
Neau, J.P.2
-
76
-
-
0001727604
-
Treatment of amyotrophic lateral sclerosis with branched chain amino acids (BCAA): results of a second study
-
Plaitakis A., Sivak M., et al. Treatment of amyotrophic lateral sclerosis with branched chain amino acids (BCAA): results of a second study. Neurology 42 suppl 3 (1992) 454
-
(1992)
Neurology
, vol.42
, Issue.SUPPL. 3
, pp. 454
-
-
Plaitakis, A.1
Sivak, M.2
-
77
-
-
0027763486
-
Branched-chain amino acids and amyotrophic lateral sclerosis: a treatment failure?
-
The Italian ALS Study Group
-
The Italian ALS Study Group. Branched-chain amino acids and amyotrophic lateral sclerosis: a treatment failure?. Neurology 43 (1993) 2466-2470
-
(1993)
Neurology
, vol.43
, pp. 2466-2470
-
-
-
78
-
-
0003257181
-
Multinational trial of branched-chain amino acids in amyotrophic lateral sclerosis
-
Steiner T.J. Multinational trial of branched-chain amino acids in amyotrophic lateral sclerosis. Muscle Nerve suppl 1 (1994) S166
-
(1994)
Muscle Nerve
, Issue.SUPPL. 1
-
-
Steiner, T.J.1
-
79
-
-
0029661207
-
A controlled trial of amino acid therapy in amyotrophic lateral sclerosis, I: clinical, functional, and maximum isometric torque data
-
Tandan R., Bromberg M.B., Forshew D., et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis, I: clinical, functional, and maximum isometric torque data. Neurology 47 (1996) 1220-1226
-
(1996)
Neurology
, vol.47
, pp. 1220-1226
-
-
Tandan, R.1
Bromberg, M.B.2
Forshew, D.3
-
81
-
-
10344245650
-
l-Threonine and the modification of ALS
-
Patten B.M., and Klein L.M. l-Threonine and the modification of ALS. Neurology 38 suppl 1 (1988) 354-355
-
(1988)
Neurology
, vol.38
, Issue.SUPPL. 1
, pp. 354-355
-
-
Patten, B.M.1
Klein, L.M.2
-
82
-
-
0024357544
-
Short-term double-blind vs placebo trial of l-threonine in amyotrophic lateral sclerosis [in French]
-
Blin O., Serratrice G., Pouget J., et al. Short-term double-blind vs placebo trial of l-threonine in amyotrophic lateral sclerosis [in French]. Presse Med 18 (1989) 1469-1470
-
(1989)
Presse Med
, vol.18
, pp. 1469-1470
-
-
Blin, O.1
Serratrice, G.2
Pouget, J.3
-
83
-
-
0026518629
-
A double-blind placebo-controlled trial of l-threonine in amyotrophic lateral sclerosis
-
Blin O., Pouget J., Aubrespy G., et al. A double-blind placebo-controlled trial of l-threonine in amyotrophic lateral sclerosis. J Neurol 239 (1992) 79-81
-
(1992)
J Neurol
, vol.239
, pp. 79-81
-
-
Blin, O.1
Pouget, J.2
Aubrespy, G.3
-
84
-
-
10344225757
-
Glycine and l-threonine therapeutic trials in amyotrophic lateral sclerosis (ALS)
-
Hugon J., and Preux P.M. Glycine and l-threonine therapeutic trials in amyotrophic lateral sclerosis (ALS). Neurology 42 suppl 3 (1992) 454
-
(1992)
Neurology
, vol.42
, Issue.SUPPL. 3
, pp. 454
-
-
Hugon, J.1
Preux, P.M.2
-
85
-
-
0026658982
-
Chronic treatment with l-threonine in amyotrophic lateral sclerosis: a pilot study
-
Testa D., Caraceni T., Fetoni V., and Girotti F. Chronic treatment with l-threonine in amyotrophic lateral sclerosis: a pilot study. Clin Neurol Neurosurg 94 (1992) 7-9
-
(1992)
Clin Neurol Neurosurg
, vol.94
, pp. 7-9
-
-
Testa, D.1
Caraceni, T.2
Fetoni, V.3
Girotti, F.4
-
86
-
-
0029753270
-
The pharmacology and mechanism of action of riluzole
-
Doble A. The pharmacology and mechanism of action of riluzole. Neurology 47 6, suppl 4 (1996) S233-S241
-
(1996)
Neurology
, vol.47
, Issue.6 SUPPL. 4
-
-
Doble, A.1
-
87
-
-
0036652765
-
Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease
-
Schiefer J., Landwehrmeyer G.B., Luesse H.G., et al. Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease. Mov Disord 17 (2002) 748-757
-
(2002)
Mov Disord
, vol.17
, pp. 748-757
-
-
Schiefer, J.1
Landwehrmeyer, G.B.2
Luesse, H.G.3
-
88
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
-
Bensimon G., Lacomblez L., and Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med 330 (1994) 585-591
-
(1994)
N Engl J Med
, vol.330
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
89
-
-
0031944832
-
An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole
-
Riviere M., Meininger V., Zeisser P., and Munsat T. An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole. Arch Neurol 55 (1998) 526-528
-
(1998)
Arch Neurol
, vol.55
, pp. 526-528
-
-
Riviere, M.1
Meininger, V.2
Zeisser, P.3
Munsat, T.4
-
91
-
-
77957110355
-
Unpublished report: Controlled Trial of Riluzole in Patients with Advanced ALS
-
Meininger V, Lacomblez L, Bensimon G. Unpublished report: Controlled Trial of Riluzole in Patients with Advanced ALS. RP 54272-302 1995. 1995.
-
(1995)
, vol.RP 54272-302
, pp. 1995
-
-
Meininger, V.1
Lacomblez, L.2
Bensimon, G.3
-
92
-
-
0000478473
-
Efficacy and safety of riluzole in patients with amyotrophic lateral sclerosis: double-blind placebo controlled study in Japan
-
Yanagisawa N., Tashirao K., Tohgi H., et al. Efficacy and safety of riluzole in patients with amyotrophic lateral sclerosis: double-blind placebo controlled study in Japan. Igakuno Ayumi 182 (1997) 851-866
-
(1997)
Igakuno Ayumi
, vol.182
, pp. 851-866
-
-
Yanagisawa, N.1
Tashirao, K.2
Tohgi, H.3
-
93
-
-
0031028227
-
Effects of riluzole on symptom progression in amyotrophic lateral sclerosis
-
Sojka P., Andersen P.M., and Forsgren L. Effects of riluzole on symptom progression in amyotrophic lateral sclerosis. Lancet 349 (1997) 176-177
-
(1997)
Lancet
, vol.349
, pp. 176-177
-
-
Sojka, P.1
Andersen, P.M.2
Forsgren, L.3
-
94
-
-
0032102114
-
Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy
-
Kalra S., Cashman N.R., Genge A., and Arnold D.L. Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy. Neuroreport 9 (1998) 1757-1761
-
(1998)
Neuroreport
, vol.9
, pp. 1757-1761
-
-
Kalra, S.1
Cashman, N.R.2
Genge, A.3
Arnold, D.L.4
-
95
-
-
0034326760
-
German open label trial of riluzole 50mg b.i.d. in treatment of amyotrophic lateral sclerosis (ALS)
-
Pongratz D., Neundorfer B., and Fischer W. German open label trial of riluzole 50mg b.i.d. in treatment of amyotrophic lateral sclerosis (ALS). J Neurol Sci 180 (2000) 82-85
-
(2000)
J Neurol Sci
, vol.180
, pp. 82-85
-
-
Pongratz, D.1
Neundorfer, B.2
Fischer, W.3
-
96
-
-
0032720023
-
The effect of riluzole in amyotrophic lateral sclerosis: a study with cortical stimulation
-
Desiato M.T., Palmieri M.G., Giacomini P., et al. The effect of riluzole in amyotrophic lateral sclerosis: a study with cortical stimulation. J Neurol Sci 169 (1999) 98-107
-
(1999)
J Neurol Sci
, vol.169
, pp. 98-107
-
-
Desiato, M.T.1
Palmieri, M.G.2
Giacomini, P.3
-
98
-
-
0034061680
-
Interest of a computerized ALS database in the diagnosis and follow-up of patients with ALS [in French]
-
Couratier P., Druet-Cabanac M., Truong C.T., et al. Interest of a computerized ALS database in the diagnosis and follow-up of patients with ALS [in French]. Rev Neurol (Paris) 156 (2000) 357-363
-
(2000)
Rev Neurol (Paris)
, vol.156
, pp. 357-363
-
-
Couratier, P.1
Druet-Cabanac, M.2
Truong, C.T.3
-
99
-
-
0011932042
-
Survival in non-riluzole treated amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) patients with disease onset before and since 1996 is identical: a clinic-based epidemiologic study
-
Brooks B.R., Belden D.S., Roelke K., et al. Survival in non-riluzole treated amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) patients with disease onset before and since 1996 is identical: a clinic-based epidemiologic study. Amyotroph Lateral Scler Other Motor Neuron Disord 2 suppl 2 (2001) 60-61
-
(2001)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.2
, Issue.SUPPL. 2
, pp. 60-61
-
-
Brooks, B.R.1
Belden, D.S.2
Roelke, K.3
-
100
-
-
0037393176
-
An outcome study of riluzole in amyotrophic lateral sclerosis. A population-based study in Ireland 1996-2000
-
Traynor B.J., Alexander M., Corr B., et al. An outcome study of riluzole in amyotrophic lateral sclerosis. A population-based study in Ireland 1996-2000. J Neurol 250 (2003) 473-479
-
(2003)
J Neurol
, vol.250
, pp. 473-479
-
-
Traynor, B.J.1
Alexander, M.2
Corr, B.3
-
101
-
-
0035543029
-
The Rilutek (riluzole) Global Early Access Programme: an open-label safety evaluation in the treatment of amyotrophic lateral sclerosis
-
Debove C., Zeisser P., Salzman P.M., et al. The Rilutek (riluzole) Global Early Access Programme: an open-label safety evaluation in the treatment of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2 (2001) 153-158
-
(2001)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.2
, pp. 153-158
-
-
Debove, C.1
Zeisser, P.2
Salzman, P.M.3
-
103
-
-
0036257090
-
A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis
-
Bensimon G., Lacomblez L., Delumeau J.C., et al. A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis. J Neurol 249 (2002) 609-615
-
(2002)
J Neurol
, vol.249
, pp. 609-615
-
-
Bensimon, G.1
Lacomblez, L.2
Delumeau, J.C.3
-
104
-
-
0032734523
-
Do the benefits of currently available treatments justify early diagnosis and treatment of amyotrophic lateral sclerosis? Arguments against
-
Ludolph A.C., and Riepe M.W. Do the benefits of currently available treatments justify early diagnosis and treatment of amyotrophic lateral sclerosis? Arguments against. Neurology 53 8, suppl 5 (1999) S46-S49
-
(1999)
Neurology
, vol.53
, Issue.8 SUPPL. 5
-
-
Ludolph, A.C.1
Riepe, M.W.2
-
105
-
-
0034517831
-
What has changed with riluzole?
-
Meininger V., Lacomblez L., and Salachas F. What has changed with riluzole?. J Neurol 246 suppl 6 (2000) 19-22
-
(2000)
J Neurol
, vol.246
, Issue.SUPPL. 6
, pp. 19-22
-
-
Meininger, V.1
Lacomblez, L.2
Salachas, F.3
-
106
-
-
0037047014
-
Early symptom progression rate is related to ALS outcome: a prospective population-based study
-
Chio A., Mora G., Leone M., et al. Early symptom progression rate is related to ALS outcome: a prospective population-based study. Neurology 59 (2002) 99-103
-
(2002)
Neurology
, vol.59
, pp. 99-103
-
-
Chio, A.1
Mora, G.2
Leone, M.3
-
107
-
-
0036762085
-
Limitations of inferences from observational databases in amyotrophic lateral sclerosis: all that glitters is not gold
-
Armon C., Guiloff R.J., and Bedlack R. Limitations of inferences from observational databases in amyotrophic lateral sclerosis: all that glitters is not gold. Amyotroph Lateral Scler Other Motor Neuron Disord 3 (2002) 109-112
-
(2002)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.3
, pp. 109-112
-
-
Armon, C.1
Guiloff, R.J.2
Bedlack, R.3
-
108
-
-
17144450273
-
Practice advisory on the treatment of amyotrophic lateral sclerosis with riluzole: report of the Quality Standards Subcommittee of the American Academy of Neurology
-
Practice advisory on the treatment of amyotrophic lateral sclerosis with riluzole: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 49 (1997) 657-659
-
(1997)
Neurology
, vol.49
, pp. 657-659
-
-
-
109
-
-
77957105093
-
-
Booth-Clibborn N, Best L, Stein K Riluzole for motor neurone disease. In L Best, R Milne, K Stein (eds), The Wessex Institute for Health Research & Development. Development & Evaluation Committee Report. 1997; 73: 1-21.
-
Booth-Clibborn N, Best L, Stein K Riluzole for motor neurone disease. In L Best, R Milne, K Stein (eds), The Wessex Institute for Health Research & Development. Development & Evaluation Committee Report. 1997; 73: 1-21.
-
-
-
-
110
-
-
0030781197
-
Cost-benefit analysis of riluzole for the treatment of amyotrophic lateral sclerosis
-
Ginsberg G.M., and Lev B. Cost-benefit analysis of riluzole for the treatment of amyotrophic lateral sclerosis. Pharmacoeconomics 12 (1997) 578-584
-
(1997)
Pharmacoeconomics
, vol.12
, pp. 578-584
-
-
Ginsberg, G.M.1
Lev, B.2
-
111
-
-
0031784927
-
ALS/MND and the perspective of health economics
-
Gray A.M. ALS/MND and the perspective of health economics. J Neurol Sci 160 suppl 1 (1998) S2-S5
-
(1998)
J Neurol Sci
, vol.160
, Issue.SUPPL. 1
-
-
Gray, A.M.1
-
112
-
-
0003971128
-
-
Sheffield: Trent Institute for Health Services Research, University of Leicester, Nottingham and Sheffield
-
Chilcott J, Golightly P, Jefferson D, et al. The Use of Riluzole in the Treatment of Amyotrophic Lateral Sclerosis (Motor Neurone Disease). Sheffield: Trent Institute for Health Services Research, University of Leicester, Nottingham and Sheffield, 1997; 1-37.
-
(1997)
The Use of Riluzole in the Treatment of Amyotrophic Lateral Sclerosis (Motor Neurone Disease)
, pp. 1-37
-
-
Chilcott, J.1
Golightly, P.2
Jefferson, D.3
-
113
-
-
0032429461
-
Economic burden of amyotrophic lateral sclerosis in the United Kingdom
-
Munsat T.M., Riviere M., Swash M., and Leclerc C. Economic burden of amyotrophic lateral sclerosis in the United Kingdom. J Med Econ 1 (1998) 235-245
-
(1998)
J Med Econ
, vol.1
, pp. 235-245
-
-
Munsat, T.M.1
Riviere, M.2
Swash, M.3
Leclerc, C.4
-
114
-
-
0032843510
-
Cost effectiveness of riluzole in amyotrophic lateral sclerosis. Italian Cooperative Group for the Study of Meta-Analysis and the Osservatorio SIFO sui Farmaci
-
Messori A., Trippoli S., Becagli P., and Zaccara G. Cost effectiveness of riluzole in amyotrophic lateral sclerosis. Italian Cooperative Group for the Study of Meta-Analysis and the Osservatorio SIFO sui Farmaci. Pharmacoeconomics 16 (1999) 153-163
-
(1999)
Pharmacoeconomics
, vol.16
, pp. 153-163
-
-
Messori, A.1
Trippoli, S.2
Becagli, P.3
Zaccara, G.4
-
115
-
-
0032937575
-
Modelling the long-term cost-effectiveness of riluzole for the treatment of amyotrophic lateral sclerosis
-
Tavakoli M., Davies H., and Malek M. Modelling the long-term cost-effectiveness of riluzole for the treatment of amyotrophic lateral sclerosis. J Med Econ 2 (1999) 1-14
-
(1999)
J Med Econ
, vol.2
, pp. 1-14
-
-
Tavakoli, M.1
Davies, H.2
Malek, M.3
-
116
-
-
0035886399
-
The cost utility analysis of riluzole for the treatment of amyotrophic lateral sclerosis in the UK
-
Tavakoli M., and Malek M. The cost utility analysis of riluzole for the treatment of amyotrophic lateral sclerosis in the UK. J Neurol Sci 191 (2001) 95-102
-
(2001)
J Neurol Sci
, vol.191
, pp. 95-102
-
-
Tavakoli, M.1
Malek, M.2
-
117
-
-
0035886429
-
Patients' health-related quality of life and utilities associated with different stages of amyotrophic lateral sclerosis
-
Kiebert G.M., Green C., Murphy C., et al. Patients' health-related quality of life and utilities associated with different stages of amyotrophic lateral sclerosis. J Neurol Sci 191 (2001) 87-93
-
(2001)
J Neurol Sci
, vol.191
, pp. 87-93
-
-
Kiebert, G.M.1
Green, C.2
Murphy, C.3
-
119
-
-
77957123589
-
The Clinical Effectiveness and Cost-Effectiveness of Riluzole for Motor Neurone Disease-An Update. West Midland Development and Evaluation Service, Full Document and Summary of Evidence Submitted to NICE
-
Bryan S, Barton P, Burls A. The Clinical Effectiveness and Cost-Effectiveness of Riluzole for Motor Neurone Disease-An Update. West Midland Development and Evaluation Service, Full Document and Summary of Evidence Submitted to NICE. Update Assessment Report. 2000.
-
(2000)
Update Assessment Report
-
-
Bryan, S.1
Barton, P.2
Burls, A.3
-
120
-
-
77957136628
-
NICE recommends riluzole for the treatment of ALS
-
Leigh N. NICE recommends riluzole for the treatment of ALS. Adv Clin Neurosci Rehabil 1 (2001) 9-12
-
(2001)
Adv Clin Neurosci Rehabil
, vol.1
, pp. 9-12
-
-
Leigh, N.1
-
121
-
-
0027759524
-
Anti-glutamate therapy in amyotrophic lateral sclerosis: a trial using lamotrigine
-
Eisen A., Stewart H., Schulzer M., and Cameron D. Anti-glutamate therapy in amyotrophic lateral sclerosis: a trial using lamotrigine. Can J Neurol Sci 20 (1993) 297-301
-
(1993)
Can J Neurol Sci
, vol.20
, pp. 297-301
-
-
Eisen, A.1
Stewart, H.2
Schulzer, M.3
Cameron, D.4
-
122
-
-
10544254257
-
Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group
-
Miller R.G., Moore D., Young L.A., et al. Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group. Neurology 47 (1996) 1383-1388
-
(1996)
Neurology
, vol.47
, pp. 1383-1388
-
-
Miller, R.G.1
Moore, D.2
Young, L.A.3
-
123
-
-
0035836669
-
ALS defeats gabapentin: reflections on another failed treatment
-
McDermott M.P., and Rowland L.P. ALS defeats gabapentin: reflections on another failed treatment. Neurology 56 (2001) 826-827
-
(2001)
Neurology
, vol.56
, pp. 826-827
-
-
McDermott, M.P.1
Rowland, L.P.2
-
124
-
-
0036359711
-
Mechanisms of disease pathogenesis in amyotrophic lateral sclerosis. A central role for calcium
-
Simpson E.P., Mosier D., and Appel S.H. Mechanisms of disease pathogenesis in amyotrophic lateral sclerosis. A central role for calcium. Adv Neurol 88 (2002) 1-19
-
(2002)
Adv Neurol
, vol.88
, pp. 1-19
-
-
Simpson, E.P.1
Mosier, D.2
Appel, S.H.3
-
125
-
-
0030006282
-
A clinical trial of verapamil in amyotrophic lateral sclerosis
-
Miller R.G., Smith S.A., Murphy J.R., et al. A clinical trial of verapamil in amyotrophic lateral sclerosis. Muscle Nerve 19 (1996) 511-515
-
(1996)
Muscle Nerve
, vol.19
, pp. 511-515
-
-
Miller, R.G.1
Smith, S.A.2
Murphy, J.R.3
-
126
-
-
0029923440
-
Controlled trial of nimodipine in amyotrophic lateral sclerosis
-
Miller R.G., Shepherd R., Dao H., et al. Controlled trial of nimodipine in amyotrophic lateral sclerosis. Neuromusc Disord 6 (1996) 101-104
-
(1996)
Neuromusc Disord
, vol.6
, pp. 101-104
-
-
Miller, R.G.1
Shepherd, R.2
Dao, H.3
-
127
-
-
0032107326
-
Assessment of the efficacy of treatment with pimozide in patients with amyotrophic lateral sclerosis. Introductory notes [in Polish]
-
Szczudlik A., Tomik B., Slowik A., and Kasprzyk K. Assessment of the efficacy of treatment with pimozide in patients with amyotrophic lateral sclerosis. Introductory notes [in Polish]. Neurol Neurochir Pol 32 (1998) 821-829
-
(1998)
Neurol Neurochir Pol
, vol.32
, pp. 821-829
-
-
Szczudlik, A.1
Tomik, B.2
Slowik, A.3
Kasprzyk, K.4
-
128
-
-
0034802145
-
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis
-
Canton T., Bohme G.A., Boireau A., et al. RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis. J Pharmacol Exp Ther 299 (2001) 314-322
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 314-322
-
-
Canton, T.1
Bohme, G.A.2
Boireau, A.3
-
129
-
-
0034036257
-
Evaluation of memantine for neuroprotection in dementia
-
Jain K.K. Evaluation of memantine for neuroprotection in dementia. Expert Opin Investig Drugs 9 (2000) 1397-1406
-
(2000)
Expert Opin Investig Drugs
, vol.9
, pp. 1397-1406
-
-
Jain, K.K.1
-
130
-
-
0032892343
-
Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist-a review of preclinical data
-
Parsons C.G., Danysz W., and Quack G. Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist-a review of preclinical data. Neuropharmacology 38 (1999) 735-767
-
(1999)
Neuropharmacology
, vol.38
, pp. 735-767
-
-
Parsons, C.G.1
Danysz, W.2
Quack, G.3
-
131
-
-
0036263210
-
Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits
-
Tateishi N., Mori T., Kagamiishi Y., et al. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J Cereb Blood Flow Metab 22 (2002) 723-734
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 723-734
-
-
Tateishi, N.1
Mori, T.2
Kagamiishi, Y.3
-
132
-
-
0023080801
-
A therapeutic trial of thymic factor in amyotrophic lateral sclerosis (ALS)
-
Provinciali L., Giovagnoli A.R., Di Bella P., et al. A therapeutic trial of thymic factor in amyotrophic lateral sclerosis (ALS). Adv Exp Med Biol 209 (1987) 293-296
-
(1987)
Adv Exp Med Biol
, vol.209
, pp. 293-296
-
-
Provinciali, L.1
Giovagnoli, A.R.2
Di Bella, P.3
-
134
-
-
0026449705
-
Long-term treatment of amyotrophic lateral sclerosis with phthalazinol
-
Majkowski J. Long-term treatment of amyotrophic lateral sclerosis with phthalazinol. Adv Second Messenger Phosphoprotein Res 25 (1992) 409-416
-
(1992)
Adv Second Messenger Phosphoprotein Res
, vol.25
, pp. 409-416
-
-
Majkowski, J.1
-
135
-
-
0027316166
-
Recombinant growth hormone treatment of amyotrophic lateral sclerosis
-
Smith R.A., Melmed S., Sherman B., et al. Recombinant growth hormone treatment of amyotrophic lateral sclerosis. Muscle Nerve 16 (1993) 624-633
-
(1993)
Muscle Nerve
, vol.16
, pp. 624-633
-
-
Smith, R.A.1
Melmed, S.2
Sherman, B.3
-
136
-
-
0020519116
-
Effect on weakness and spasticity in amyotrophic lateral sclerosis of thyrotropin-releasing hormone
-
Engel W.K., Siddique T., and Nicoloff J.T. Effect on weakness and spasticity in amyotrophic lateral sclerosis of thyrotropin-releasing hormone. Lancet 2 (1983) 73-75
-
(1983)
Lancet
, vol.2
, pp. 73-75
-
-
Engel, W.K.1
Siddique, T.2
Nicoloff, J.T.3
-
137
-
-
0021715822
-
Amyotrophic lateral sclerosis: a double-blind crossover trial of thyrotropin-releasing hormone
-
Imoto K., Saida K., Iwamura K., et al. Amyotrophic lateral sclerosis: a double-blind crossover trial of thyrotropin-releasing hormone. J Neurol Neurosurg Psychiatry 47 (1984) 1332-1334
-
(1984)
J Neurol Neurosurg Psychiatry
, vol.47
, pp. 1332-1334
-
-
Imoto, K.1
Saida, K.2
Iwamura, K.3
-
138
-
-
0021138837
-
Pulmonary effects of thyrotropin-releasing hormone in amyotrophic lateral sclerosis
-
Braun S.R., Sufit R.L., and Brooks B.R. Pulmonary effects of thyrotropin-releasing hormone in amyotrophic lateral sclerosis. Lancet 2 (1984) 529-530
-
(1984)
Lancet
, vol.2
, pp. 529-530
-
-
Braun, S.R.1
Sufit, R.L.2
Brooks, B.R.3
-
139
-
-
0021867278
-
Intrathecal thyrotropin-releasing hormone therapy of amyotrophic lateral sclerosis
-
Stober T., Schimrigk K., Dietzsch S., and Thielen T. Intrathecal thyrotropin-releasing hormone therapy of amyotrophic lateral sclerosis. J Neurol 232 (1985) 13-14
-
(1985)
J Neurol
, vol.232
, pp. 13-14
-
-
Stober, T.1
Schimrigk, K.2
Dietzsch, S.3
Thielen, T.4
-
140
-
-
0022430894
-
Trial of thyrotropin-releasing factor in amyotrophic lateral sclerosis [in French]
-
Serratrice G., Desnuelle C., Guelton C., et al. Trial of thyrotropin-releasing factor in amyotrophic lateral sclerosis [in French]. Presse Med 14 (1985) 487-488
-
(1985)
Presse Med
, vol.14
, pp. 487-488
-
-
Serratrice, G.1
Desnuelle, C.2
Guelton, C.3
-
141
-
-
0022636979
-
A double-blind, placebo-controlled trial of TRH in amyotrophic lateral sclerosis
-
Caroscio J.T., Cohen J.A., Zawodniak J., et al. A double-blind, placebo-controlled trial of TRH in amyotrophic lateral sclerosis. Neurology 36 (1986) 141-145
-
(1986)
Neurology
, vol.36
, pp. 141-145
-
-
Caroscio, J.T.1
Cohen, J.A.2
Zawodniak, J.3
-
142
-
-
0022636980
-
Controlled trial of thyrotropin releasing hormone in amyotrophic lateral sclerosis
-
Brooke M.H., Florence J.M., Heller S.L., et al. Controlled trial of thyrotropin releasing hormone in amyotrophic lateral sclerosis. Neurology 36 (1986) 146-151
-
(1986)
Neurology
, vol.36
, pp. 146-151
-
-
Brooke, M.H.1
Florence, J.M.2
Heller, S.L.3
-
143
-
-
0022633475
-
Amyotrophic lateral sclerosis: effects of acute intravenous and chronic subcutaneous administration of thyrotropin-releasing hormone in controlled trials
-
Mitsumoto H., Salgado E.D., Negroski D., et al. Amyotrophic lateral sclerosis: effects of acute intravenous and chronic subcutaneous administration of thyrotropin-releasing hormone in controlled trials. Neurology 36 (1986) 152-159
-
(1986)
Neurology
, vol.36
, pp. 152-159
-
-
Mitsumoto, H.1
Salgado, E.D.2
Negroski, D.3
-
144
-
-
0022542567
-
Treatment of amyotrophic lateral sclerosis with thyrotropin releasing hormone [in French]
-
Serratrice G., Desnuelle C., Crevat A., et al. Treatment of amyotrophic lateral sclerosis with thyrotropin releasing hormone [in French]. Rev Neurol (Paris) 142 (1986) 133-139
-
(1986)
Rev Neurol (Paris)
, vol.142
, pp. 133-139
-
-
Serratrice, G.1
Desnuelle, C.2
Crevat, A.3
-
145
-
-
0022498007
-
Treatment of amyotrophic lateral sclerosis with thyrotropin-releasing hormone (TRH)
-
Yamane K., Osawa M., Kobayashi I., and Maruyama S. Treatment of amyotrophic lateral sclerosis with thyrotropin-releasing hormone (TRH). Jpn J Psychiatry Neurol 40 (1986) 179-187
-
(1986)
Jpn J Psychiatry Neurol
, vol.40
, pp. 179-187
-
-
Yamane, K.1
Osawa, M.2
Kobayashi, I.3
Maruyama, S.4
-
146
-
-
0022881494
-
Preliminary clinical study on the treatment of amyotrophic lateral sclerosis with TRH [in Italian]
-
Formisano R., Antonini G., Bove R., et al. Preliminary clinical study on the treatment of amyotrophic lateral sclerosis with TRH [in Italian]. Clin Ter 119 (1986) 479-481
-
(1986)
Clin Ter
, vol.119
, pp. 479-481
-
-
Formisano, R.1
Antonini, G.2
Bove, R.3
-
147
-
-
0023142099
-
Intravenous thyrotropin-releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies
-
Brooks B.R., Sufit R.L., Montgomery G.K., et al. Intravenous thyrotropin-releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies. Neurol Clin 5 (1987) 143-158
-
(1987)
Neurol Clin
, vol.5
, pp. 143-158
-
-
Brooks, B.R.1
Sufit, R.L.2
Montgomery, G.K.3
-
148
-
-
0023061603
-
Therapeutic trial of intrathecal thyrotropin-releasing hormone (TRH) and a TRH-analogue in amyotrophic lateral sclerosis (ALS)
-
Thielen T., Stober T., and Schimrigk K. Therapeutic trial of intrathecal thyrotropin-releasing hormone (TRH) and a TRH-analogue in amyotrophic lateral sclerosis (ALS). Adv Exp Med Biol 209 (1987) 305-308
-
(1987)
Adv Exp Med Biol
, vol.209
, pp. 305-308
-
-
Thielen, T.1
Stober, T.2
Schimrigk, K.3
-
149
-
-
0023105612
-
Treatment of amyotrophic lateral sclerosis with the TRH analog DN-1417
-
Hawley R.J., Kratz R., Goodman R.R., et al. Treatment of amyotrophic lateral sclerosis with the TRH analog DN-1417. Neurology 37 (1987) 715-717
-
(1987)
Neurology
, vol.37
, pp. 715-717
-
-
Hawley, R.J.1
Kratz, R.2
Goodman, R.R.3
-
150
-
-
0023107208
-
Intrathecal thyrotropin-releasing hormone in amyotrophic lateral sclerosis
-
Munsat T.L., Taft J., and Kasdon D. Intrathecal thyrotropin-releasing hormone in amyotrophic lateral sclerosis. Neurol Clin 5 (1987) 159-170
-
(1987)
Neurol Clin
, vol.5
, pp. 159-170
-
-
Munsat, T.L.1
Taft, J.2
Kasdon, D.3
-
151
-
-
0023746266
-
Prolonged intrathecal infusion of thyrotropin releasing hormone in amyotrophic lateral sclerosis
-
Munsat T.L., Taft J., Kasdon D., and Jackson I.M. Prolonged intrathecal infusion of thyrotropin releasing hormone in amyotrophic lateral sclerosis. Ann N Y Acad Sci 531 (1988) 187-193
-
(1988)
Ann N Y Acad Sci
, vol.531
, pp. 187-193
-
-
Munsat, T.L.1
Taft, J.2
Kasdon, D.3
Jackson, I.M.4
-
152
-
-
0024227863
-
Clinical, electrophysiologic and endocrine effects of the perfusion of high doses of TRH in amyotrophic lateral sclerosis [in French]
-
Gueguen B., Puymirat J., Grouselle D., et al. Clinical, electrophysiologic and endocrine effects of the perfusion of high doses of TRH in amyotrophic lateral sclerosis [in French]. Rev Neurol (Paris) 144 (1988) 704-709
-
(1988)
Rev Neurol (Paris)
, vol.144
, pp. 704-709
-
-
Gueguen, B.1
Puymirat, J.2
Grouselle, D.3
-
154
-
-
0025605323
-
Amyotrophic lateral sclerosis: thyroid and prolactin hormone changes in thyrotropin-releasing hormone therapy
-
Testa D., Chiodini P.G., Girotti F., and Attanasio R. Amyotrophic lateral sclerosis: thyroid and prolactin hormone changes in thyrotropin-releasing hormone therapy. Ital J Neurol Sci 11 (1990) 601-603
-
(1990)
Ital J Neurol Sci
, vol.11
, pp. 601-603
-
-
Testa, D.1
Chiodini, P.G.2
Girotti, F.3
Attanasio, R.4
-
155
-
-
0024982207
-
Effect of thyroliberin treatment on the thyrotropin and prolactin levels in patients with amyotrophic lateral sclerosis [in Polish]
-
Klimek A., Szulc-Kuberska J., and Stepien H. Effect of thyroliberin treatment on the thyrotropin and prolactin levels in patients with amyotrophic lateral sclerosis [in Polish]. Neurol Neurochir Pol 24 (1990) 31-36
-
(1990)
Neurol Neurochir Pol
, vol.24
, pp. 31-36
-
-
Klimek, A.1
Szulc-Kuberska, J.2
Stepien, H.3
-
156
-
-
0026729250
-
Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: experience with an intrathecal drug delivery system
-
Munsat T.L., Taft J., Jackson I.M., et al. Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: experience with an intrathecal drug delivery system. Neurology 42 (1992) 1049-1053
-
(1992)
Neurology
, vol.42
, pp. 1049-1053
-
-
Munsat, T.L.1
Taft, J.2
Jackson, I.M.3
-
157
-
-
0026601727
-
Treatment of amyotrophic lateral sclerosis with daily intrathecal TRH. A year's experience. Pilot study II [in Spanish]
-
Patrignani J., Proano J., and Morales M.D. Treatment of amyotrophic lateral sclerosis with daily intrathecal TRH. A year's experience. Pilot study II [in Spanish]. Neurologia 7 (1992) 4-9
-
(1992)
Neurologia
, vol.7
, pp. 4-9
-
-
Patrignani, J.1
Proano, J.2
Morales, M.D.3
-
158
-
-
0023628897
-
Current status of thyrotropin-releasing hormone therapy in amyotrophic lateral sclerosis. Committee on Health Care Issues, American Neurological Association
-
Current status of thyrotropin-releasing hormone therapy in amyotrophic lateral sclerosis. Committee on Health Care Issues, American Neurological Association. Ann Neurol 22 (1987) 541-543
-
(1987)
Ann Neurol
, vol.22
, pp. 541-543
-
-
-
159
-
-
0024464350
-
Thyrotropin-releasing hormone in ALS. Are the results of clinical studies inconsistent?
-
Brooke M.H. Thyrotropin-releasing hormone in ALS. Are the results of clinical studies inconsistent?. Ann N Y Acad Sci 553 (1989) 422-430
-
(1989)
Ann N Y Acad Sci
, vol.553
, pp. 422-430
-
-
Brooke, M.H.1
-
160
-
-
0024476951
-
Protirelin (thyrotropin-releasing hormone) in amyotrophic lateral sclerosis. The role of androgens
-
Miller S.C., and Warnick J.E. Protirelin (thyrotropin-releasing hormone) in amyotrophic lateral sclerosis. The role of androgens. Arch Neurol 46 (1989) 330-335
-
(1989)
Arch Neurol
, vol.46
, pp. 330-335
-
-
Miller, S.C.1
Warnick, J.E.2
-
161
-
-
0026550179
-
Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro
-
Martinou J.C., Martinou I., and Kato A.C. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro. Neuron 8 (1992) 737-744
-
(1992)
Neuron
, vol.8
, pp. 737-744
-
-
Martinou, J.C.1
Martinou, I.2
Kato, A.C.3
-
162
-
-
0028027060
-
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF
-
Mitsumoto H., Ikeda K., Klinkosz B., et al. Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF. Science 265 (1994) 1107-1110
-
(1994)
Science
, vol.265
, pp. 1107-1110
-
-
Mitsumoto, H.1
Ikeda, K.2
Klinkosz, B.3
-
163
-
-
2442646665
-
A double-blind placebo-controlled clinical trial of sub-cutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group
-
The ALS CNTF Treatment Study Group
-
The ALS CNTF Treatment Study Group. A double-blind placebo-controlled clinical trial of sub-cutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group. Neurology 46 (1996) 1244-1249
-
(1996)
Neurology
, vol.46
, pp. 1244-1249
-
-
-
164
-
-
0030678474
-
Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials
-
Cedarbaum J.M., and Stambler N. Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials. J Neurol Sci 152 suppl 1 (1997) S1-S9
-
(1997)
J Neurol Sci
, vol.152
, Issue.SUPPL. 1
-
-
Cedarbaum, J.M.1
Stambler, N.2
-
165
-
-
0029952139
-
Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis
-
Miller R.G., Bryan W.W., Dietz M.A., et al. Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis. Neurology 47 (1996) 1329-1331
-
(1996)
Neurology
, vol.47
, pp. 1329-1331
-
-
Miller, R.G.1
Bryan, W.W.2
Dietz, M.A.3
-
166
-
-
0031929662
-
Prognostic indicators of survival in ALS. ALS CNTF Treatment Study Group
-
Stambler N., Charatan M., and Cedarbaum J.M. Prognostic indicators of survival in ALS. ALS CNTF Treatment Study Group. Neurology 50 (1998) 66-72
-
(1998)
Neurology
, vol.50
, pp. 66-72
-
-
Stambler, N.1
Charatan, M.2
Cedarbaum, J.M.3
-
167
-
-
0031028248
-
Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial)
-
Penn R.D., Kroin J.S., York M.M., and Cedarbaum J.M. Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial). Neurosurgery 40 (1997) 94-99
-
(1997)
Neurosurgery
, vol.40
, pp. 94-99
-
-
Penn, R.D.1
Kroin, J.S.2
York, M.M.3
Cedarbaum, J.M.4
-
168
-
-
0027762580
-
Insulin-like growth factor-I: potential for treatment of motor neuronal disorders
-
Lewis M.E., Neff N.T., Contreras P.C., et al. Insulin-like growth factor-I: potential for treatment of motor neuronal disorders. Exp Neurol 124 (1993) 73-88
-
(1993)
Exp Neurol
, vol.124
, pp. 73-88
-
-
Lewis, M.E.1
Neff, N.T.2
Contreras, P.C.3
-
169
-
-
0027527205
-
Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival
-
Neff N.T., Prevette D., Houenou L.J., et al. Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival. J Neurobiol 24 (1993) 1578-1588
-
(1993)
J Neurobiol
, vol.24
, pp. 1578-1588
-
-
Neff, N.T.1
Prevette, D.2
Houenou, L.J.3
-
170
-
-
0032588644
-
Cost effectiveness of recombinant human insulin-like growth factor I therapy in patients with ALS
-
Ackerman S.J., Sullivan E.M., Beusterien K.M., et al. Cost effectiveness of recombinant human insulin-like growth factor I therapy in patients with ALS. Pharmacoeconomics 15 (1999) 179-195
-
(1999)
Pharmacoeconomics
, vol.15
, pp. 179-195
-
-
Ackerman, S.J.1
Sullivan, E.M.2
Beusterien, K.M.3
-
171
-
-
0036046465
-
Recombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron disease
-
CD002064
-
Mitchell JD, Wokke JH, Borasio GD. Recombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev 2002; CD002064.
-
(2002)
Cochrane Database Syst Rev
-
-
Mitchell, J.D.1
Wokke, J.H.2
Borasio, G.D.3
-
172
-
-
0027739690
-
Motoneuron survival factors: biological roles and therapeutic potential
-
Henderson C.E., Bloch-Gallego E., Camu W., et al. Motoneuron survival factors: biological roles and therapeutic potential. Neuromusc Disord 3 (1993) 455-458
-
(1993)
Neuromusc Disord
, vol.3
, pp. 455-458
-
-
Henderson, C.E.1
Bloch-Gallego, E.2
Camu, W.3
-
173
-
-
0028916844
-
Effects of brain-derived neurotrophic factor on motor dys-function in wobbler mouse motor neuron disease
-
Ikeda K., Klinkosz B., Greene T., et al. Effects of brain-derived neurotrophic factor on motor dys-function in wobbler mouse motor neuron disease. Ann Neurol 37 (1995) 505-511
-
(1995)
Ann Neurol
, vol.37
, pp. 505-511
-
-
Ikeda, K.1
Klinkosz, B.2
Greene, T.3
-
174
-
-
0344076149
-
A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)
-
The BDNF Study Group (Phase III)
-
The BDNF Study Group (Phase III). A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III). Neurology 52 (1999) 1427-1433
-
(1999)
Neurology
, vol.52
, pp. 1427-1433
-
-
-
175
-
-
0034208461
-
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
-
Ochs G., Penn R.D., York M., et al. A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1 (2000) 201-206
-
(2000)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, pp. 201-206
-
-
Ochs, G.1
Penn, R.D.2
York, M.3
-
176
-
-
0027303254
-
Protective effects of SR 57746A in central and peripheral models of neurodegenerative disorders in rodents and primates
-
Fournier J., Steinberg R., Gauthier T., et al. Protective effects of SR 57746A in central and peripheral models of neurodegenerative disorders in rodents and primates. Neuroscience 55 (1993) 629-641
-
(1993)
Neuroscience
, vol.55
, pp. 629-641
-
-
Fournier, J.1
Steinberg, R.2
Gauthier, T.3
-
178
-
-
0031579428
-
5-HT1a receptors mediate the neurotrophic effect of serotonin on developing dentate granule cells
-
Yan W., Wilson C.C., and Haring J.H. 5-HT1a receptors mediate the neurotrophic effect of serotonin on developing dentate granule cells. Brain Res Dev Brain Res 98 (1997) 185-190
-
(1997)
Brain Res Dev Brain Res
, vol.98
, pp. 185-190
-
-
Yan, W.1
Wilson, C.C.2
Haring, J.H.3
-
179
-
-
77957127783
-
11C]-WAY100635 PET: A potential in vivo marker for ALS?
-
11C]-WAY100635 PET: A potential in vivo marker for ALS?. Neurology 58 7 suppl 3 (2002) A413
-
(2002)
Neurology
, vol.58
, Issue.7 SUPPL. 3
-
-
Turner, M.R.1
Rabiner, E.A.2
Grasby, P.3
-
180
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse B., Moons L., Storkebaum E., et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 28 (2001) 131-138
-
(2001)
Nat Genet
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
Moons, L.2
Storkebaum, E.3
-
181
-
-
0035444173
-
Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
-
Bordet T., Lesbordes J.C., Rouhani S., et al. Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice. Hum Mol Genet 10 (2001) 1925-1933
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1925-1933
-
-
Bordet, T.1
Lesbordes, J.C.2
Rouhani, S.3
-
182
-
-
0036292375
-
Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy
-
Acsadi G., Anguelov R.A., Yang H., et al. Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy. Hum Gene Ther 13 (2002) 1047-1059
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1047-1059
-
-
Acsadi, G.1
Anguelov, R.A.2
Yang, H.3
-
183
-
-
0037104725
-
Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis
-
Wang L.J., Lu Y.Y., Muramatsu S., et al. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis. J Neurosci 22 (2002) 6920-6928
-
(2002)
J Neurosci
, vol.22
, pp. 6920-6928
-
-
Wang, L.J.1
Lu, Y.Y.2
Muramatsu, S.3
-
184
-
-
0036022401
-
Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis
-
Manabe Y., Nagano I., Gazi M.S., et al. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis. Apoptosis 7 (2002) 329-334
-
(2002)
Apoptosis
, vol.7
, pp. 329-334
-
-
Manabe, Y.1
Nagano, I.2
Gazi, M.S.3
-
185
-
-
0029438064
-
Amyotrophic lateral sclerosis. An autoimmune disease?
-
Drachman D.B., Fishman P.S., Rothstein J.D., et al. Amyotrophic lateral sclerosis. An autoimmune disease?. Adv Neurol 68 (1995) 59-65
-
(1995)
Adv Neurol
, vol.68
, pp. 59-65
-
-
Drachman, D.B.1
Fishman, P.S.2
Rothstein, J.D.3
-
187
-
-
0024994099
-
IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis
-
Engelhardt J.I., and Appel S.H. IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch Neurol 47 (1990) 1210-1216
-
(1990)
Arch Neurol
, vol.47
, pp. 1210-1216
-
-
Engelhardt, J.I.1
Appel, S.H.2
-
188
-
-
0021253595
-
A double-blind controlled trial of bovine brain gangliosides in amyotrophic lateral sclerosis
-
Bradley W.G., Hedlund W., Cooper C., et al. A double-blind controlled trial of bovine brain gangliosides in amyotrophic lateral sclerosis. Neurology 34 (1984) 1079-1082
-
(1984)
Neurology
, vol.34
, pp. 1079-1082
-
-
Bradley, W.G.1
Hedlund, W.2
Cooper, C.3
-
192
-
-
0032407091
-
Multifocal motor neuropathy: diagnosis and treatment
-
Pestronk A. Multifocal motor neuropathy: diagnosis and treatment. Neurology 51 6, suppl 5 (1998) S22-S24
-
(1998)
Neurology
, vol.51
, Issue.6 SUPPL. 5
-
-
Pestronk, A.1
-
193
-
-
0015918109
-
Amyotrophic lateral sclerosis: effect of serum on anterior horn cells in tissue culture
-
Wolfgram F., and Myers L. Amyotrophic lateral sclerosis: effect of serum on anterior horn cells in tissue culture. Science 179 (1973) 579-580
-
(1973)
Science
, vol.179
, pp. 579-580
-
-
Wolfgram, F.1
Myers, L.2
-
194
-
-
0026473192
-
Serum antibodies to l-type calcium channels in patients with amyotrophic lateral sclerosis
-
Smith R.G., Hamilton S., Hofmann F., et al. Serum antibodies to l-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med 327 (1992) 1721-1728
-
(1992)
N Engl J Med
, vol.327
, pp. 1721-1728
-
-
Smith, R.G.1
Hamilton, S.2
Hofmann, F.3
-
195
-
-
0025185079
-
Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis
-
Troost D., Van den Oord J.J., and Vianney de Jong J.M. Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol 16 (1990) 401-410
-
(1990)
Neuropathol Appl Neurobiol
, vol.16
, pp. 401-410
-
-
Troost, D.1
Van den Oord, J.J.2
Vianney de Jong, J.M.3
-
196
-
-
0029042532
-
Antibodies against microglia/brain macrophages in the cerebrospinal fluid of a patient with acute amyotrophic lateral sclerosis and presenile dementia
-
Banati R.B., Gehrmann J., Kellner M., and Holsboer F. Antibodies against microglia/brain macrophages in the cerebrospinal fluid of a patient with acute amyotrophic lateral sclerosis and presenile dementia. Clin Neuropathol 14 (1995) 197-200
-
(1995)
Clin Neuropathol
, vol.14
, pp. 197-200
-
-
Banati, R.B.1
Gehrmann, J.2
Kellner, M.3
Holsboer, F.4
-
197
-
-
0021026443
-
Plasmapheresis with immunosuppression in amyotrophic lateral sclerosis
-
Kelemen J., Hedlund W., Orlin J.B., et al. Plasmapheresis with immunosuppression in amyotrophic lateral sclerosis. Arch Neurol 40 (1983) 752-753
-
(1983)
Arch Neurol
, vol.40
, pp. 752-753
-
-
Kelemen, J.1
Hedlund, W.2
Orlin, J.B.3
-
198
-
-
0022521502
-
Intrathecal administration of natural human interferon alpha in amyotrophic lateral sclerosis
-
Mora J.S., Munsat T.L., Kao K.P., et al. Intrathecal administration of natural human interferon alpha in amyotrophic lateral sclerosis. Neurology 36 (1986) 1137-1140
-
(1986)
Neurology
, vol.36
, pp. 1137-1140
-
-
Mora, J.S.1
Munsat, T.L.2
Kao, K.P.3
-
199
-
-
0022637677
-
Failure of immunosuppression with a ten-to 14-day course of high-dose intravenous cyclophosphamide to alter the progression of amyotrophic lateral sclerosis
-
Brown Jr. R.H., Hauser S.L., Harrington H., and Weiner H.L. Failure of immunosuppression with a ten-to 14-day course of high-dose intravenous cyclophosphamide to alter the progression of amyotrophic lateral sclerosis. Arch Neurol 43 (1986) 383-384
-
(1986)
Arch Neurol
, vol.43
, pp. 383-384
-
-
Brown Jr., R.H.1
Hauser, S.L.2
Harrington, H.3
Weiner, H.L.4
-
200
-
-
0027972434
-
Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder
-
Tan E., Lynn D.J., Amato A.A., et al. Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder. Arch Neurol 51 (1994) 194-200
-
(1994)
Arch Neurol
, vol.51
, pp. 194-200
-
-
Tan, E.1
Lynn, D.J.2
Amato, A.A.3
-
201
-
-
0023949295
-
A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis
-
Appel S.H., Stewart S.S., Appel V., et al. A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral sclerosis. Arch Neurol 45 (1988) 381-386
-
(1988)
Arch Neurol
, vol.45
, pp. 381-386
-
-
Appel, S.H.1
Stewart, S.S.2
Appel, V.3
-
202
-
-
0025072761
-
Immunosuppressive treatment of patients with amyotrophic lateral sclerosis
-
Werdelin L., Boysen G., Jensen T.S., and Mogensen P. Immunosuppressive treatment of patients with amyotrophic lateral sclerosis. Acta Neurol Scand 82 (1990) 132-134
-
(1990)
Acta Neurol Scand
, vol.82
, pp. 132-134
-
-
Werdelin, L.1
Boysen, G.2
Jensen, T.S.3
Mogensen, P.4
-
203
-
-
0026535492
-
Dermal, serological and CSF changes in amyotrophic lateral sclerosis with and without intrathecal interferon beta treatment
-
Westarp M.E., Westphal K.P., Kolde G., et al. Dermal, serological and CSF changes in amyotrophic lateral sclerosis with and without intrathecal interferon beta treatment. Int J Clin Pharmacol Ther Toxicol 30 (1992) 81-93
-
(1992)
Int J Clin Pharmacol Ther Toxicol
, vol.30
, pp. 81-93
-
-
Westarp, M.E.1
Westphal, K.P.2
Kolde, G.3
-
204
-
-
0028121750
-
Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation
-
Drachman D.B., Chaudhry V., Cornblath D., et al. Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation. Ann Neurol 35 (1994) 142-150
-
(1994)
Ann Neurol
, vol.35
, pp. 142-150
-
-
Drachman, D.B.1
Chaudhry, V.2
Cornblath, D.3
-
205
-
-
0021828175
-
Levamisole is ineffective in the treatment of amyotrophic lateral sclerosis
-
Olarte M.R., and Shafer S.Q. Levamisole is ineffective in the treatment of amyotrophic lateral sclerosis. Neurology 35 (1985) 1063-1066
-
(1985)
Neurology
, vol.35
, pp. 1063-1066
-
-
Olarte, M.R.1
Shafer, S.Q.2
-
207
-
-
0030042956
-
Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis
-
Meucci N., Nobile-Orazio E., and Scarlato G. Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis. J Neurol 243 (1996) 117-120
-
(1996)
J Neurol
, vol.243
, pp. 117-120
-
-
Meucci, N.1
Nobile-Orazio, E.2
Scarlato, G.3
-
208
-
-
0028155973
-
Multifocal motor neuropathy: electrodiagnostic features
-
Chaudhry V., Corse A.M., Cornblath D.R., et al. Multifocal motor neuropathy: electrodiagnostic features. Muscle Nerve 17 (1994) 198-205
-
(1994)
Muscle Nerve
, vol.17
, pp. 198-205
-
-
Chaudhry, V.1
Corse, A.M.2
Cornblath, D.R.3
-
209
-
-
0034130427
-
Natural history of 46 patients with multifocal motor neuropathy with conduction block
-
Taylor B.V., Wright R.A., Harper C.M., and Dyck P.J. Natural history of 46 patients with multifocal motor neuropathy with conduction block. Muscle Nerve 23 (2000) 900-908
-
(2000)
Muscle Nerve
, vol.23
, pp. 900-908
-
-
Taylor, B.V.1
Wright, R.A.2
Harper, C.M.3
Dyck, P.J.4
-
210
-
-
0035795088
-
Multifocal motor neuropathy
-
Nobile-Orazio E. Multifocal motor neuropathy. J Neuroimmunol 115 (2001) 4-18
-
(2001)
J Neuroimmunol
, vol.115
, pp. 4-18
-
-
Nobile-Orazio, E.1
-
211
-
-
0028330355
-
M1 antibodies: a double-blind, placebo-controlled study
-
M1 antibodies: a double-blind, placebo-controlled study. Neurology 44 3, pt 1 (1994) 429-432
-
(1994)
Neurology
, vol.44
, Issue.3 PART 1
, pp. 429-432
-
-
Azulay, J.P.1
Blin, O.2
Pouget, J.3
-
212
-
-
0029114530
-
Treatment of multifocal motor neuropathy with high dose intravenous immunoglobulins: a double blind, placebo controlled study
-
Van den Berg L.H., Kerkhoff H., Oey P.L., et al. Treatment of multifocal motor neuropathy with high dose intravenous immunoglobulins: a double blind, placebo controlled study. J Neurol Neurosurg Psychiatry 59 (1995) 248-252
-
(1995)
J Neurol Neurosurg Psychiatry
, vol.59
, pp. 248-252
-
-
Van den Berg, L.H.1
Kerkhoff, H.2
Oey, P.L.3
-
213
-
-
0034649381
-
Multifocal motor neuropathy improved by IVIg: randomized, double-blind, placebo-controlled study
-
Federico P., Zochodne D.W., Hahn A.F., et al. Multifocal motor neuropathy improved by IVIg: randomized, double-blind, placebo-controlled study. Neurology 55 (2000) 1256-1262
-
(2000)
Neurology
, vol.55
, pp. 1256-1262
-
-
Federico, P.1
Zochodne, D.W.2
Hahn, A.F.3
-
214
-
-
0035182250
-
Intravenous immunoglobulin therapy in multifocal motor neuropathy: a double-blind, placebo-controlled study
-
Leger J.M., Chassande B., Musset L., et al. Intravenous immunoglobulin therapy in multifocal motor neuropathy: a double-blind, placebo-controlled study. Brain 124 pt 1 (2001) 145-153
-
(2001)
Brain
, vol.124
, Issue.PART 1
, pp. 145-153
-
-
Leger, J.M.1
Chassande, B.2
Musset, L.3
-
215
-
-
0030967644
-
Long term follow up of multifocal motor neuropathy with conduction block under treatment
-
Azulay J.P., Rihet P., Pouget J., et al. Long term follow up of multifocal motor neuropathy with conduction block under treatment. J Neurol Neurosurg Psychiatry 62 (1997) 391-394
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.62
, pp. 391-394
-
-
Azulay, J.P.1
Rihet, P.2
Pouget, J.3
-
216
-
-
0033673058
-
Multifocal motor neuropathy: diagnostic criteria that predict the response to immunoglobulin treatment
-
Berg-Vos R.M., Franssen H., Wokke J.H., et al. Multifocal motor neuropathy: diagnostic criteria that predict the response to immunoglobulin treatment. Ann Neurol 48 (2000) 919-926
-
(2000)
Ann Neurol
, vol.48
, pp. 919-926
-
-
Berg-Vos, R.M.1
Franssen, H.2
Wokke, J.H.3
-
217
-
-
0036262603
-
Multifocal motor neuropathy: clinical and immunological features and response to IVIg in relation to the presence and degree of motor conduction block
-
Nobile-Orazio E., Cappellari A., Meucci N., et al. Multifocal motor neuropathy: clinical and immunological features and response to IVIg in relation to the presence and degree of motor conduction block. J Neurol Neurosurg Psychiatry 72 (2002) 761-766
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.72
, pp. 761-766
-
-
Nobile-Orazio, E.1
Cappellari, A.2
Meucci, N.3
-
218
-
-
0033038070
-
Use of human intravenous immunoglobulin in lower motor neuron syndromes
-
Ellis C.M., Leary S., Payan J., et al. Use of human intravenous immunoglobulin in lower motor neuron syndromes. J Neurol Neurosurg Psychiatry 67 (1999) 15-19
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 15-19
-
-
Ellis, C.M.1
Leary, S.2
Payan, J.3
-
220
-
-
12044249765
-
Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity
-
Siddique T., Figlewicz D.A., Pericak-Vance M.A., et al. Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity. N Engl J Med 324 (1991) 1381-1384
-
(1991)
N Engl J Med
, vol.324
, pp. 1381-1384
-
-
Siddique, T.1
Figlewicz, D.A.2
Pericak-Vance, M.A.3
-
221
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
222
-
-
0030450004
-
Cu/Zn superoxide dismutase gene mutations in amyotrophic lateral sclerosis: correlation between genotype and clinical features
-
Radunovic A., and Leigh P.N. Cu/Zn superoxide dismutase gene mutations in amyotrophic lateral sclerosis: correlation between genotype and clinical features. J Neurol Neurosurg Psychiatry 61 (1996) 565-572
-
(1996)
J Neurol Neurosurg Psychiatry
, vol.61
, pp. 565-572
-
-
Radunovic, A.1
Leigh, P.N.2
-
223
-
-
0031057003
-
Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis
-
Cudkowicz M.E., McKenna-Yasek D., Sapp P.E., et al. Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis. Ann Neurol 41 (1997) 210-221
-
(1997)
Ann Neurol
, vol.41
, pp. 210-221
-
-
Cudkowicz, M.E.1
McKenna-Yasek, D.2
Sapp, P.E.3
-
224
-
-
0032692608
-
Clinical characteristics of SOD1 gene mutations in UK families with ALS
-
Orrell R.W., Habgood J.J., Malaspina A., et al. Clinical characteristics of SOD1 gene mutations in UK families with ALS. J Neurol Sci 169 (1999) 56-60
-
(1999)
J Neurol Sci
, vol.169
, pp. 56-60
-
-
Orrell, R.W.1
Habgood, J.J.2
Malaspina, A.3
-
226
-
-
0029012964
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
[published erratum in:].
-
Gurney M.E., Pu H., Chiu A.Y., et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 269 (1995) 149 [published erratum in:].
-
(1995)
Science
, vol.269
, pp. 149
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
-
227
-
-
0028284779
-
-
Science 264 (1994) 1772-1775
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
-
230
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume A.G., Elliott J.L., Hoffman E.K., et al. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet 13 (1996) 43-47
-
(1996)
Nat Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
-
231
-
-
0030810921
-
Intrathecal administration of recombinant human superoxide dismutase 1 in amyotrophic lateral sclerosis: a preliminary safety and pharmacokinetic study
-
Cudkowicz M.E., Warren L., Francis J.W., et al. Intrathecal administration of recombinant human superoxide dismutase 1 in amyotrophic lateral sclerosis: a preliminary safety and pharmacokinetic study. Neurology 49 (1997) 213-222
-
(1997)
Neurology
, vol.49
, pp. 213-222
-
-
Cudkowicz, M.E.1
Warren, L.2
Francis, J.W.3
-
232
-
-
0036071852
-
Overexpression of manganese superoxide dismutase attenuates neuronal death in human cells expressing mutant (G37R) Cu/Zn-superoxide dismutase
-
Flanagan S.W., Anderson R.D., Ross M.A., and Oberley L.W. Overexpression of manganese superoxide dismutase attenuates neuronal death in human cells expressing mutant (G37R) Cu/Zn-superoxide dismutase. J Neurochem 81 (2002) 170-177
-
(2002)
J Neurochem
, vol.81
, pp. 170-177
-
-
Flanagan, S.W.1
Anderson, R.D.2
Ross, M.A.3
Oberley, L.W.4
-
233
-
-
0037111503
-
Do oxidatively modified proteins cause ALS?
-
Valentine J.S. Do oxidatively modified proteins cause ALS?. Free Radic Biol Med 33 (2002) 1314-1320
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1314-1320
-
-
Valentine, J.S.1
-
234
-
-
0029671220
-
Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos M., Goto J.J., Rabizadeh S., et al. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science 271 (1996) 515-518
-
(1996)
Science
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
Goto, J.J.2
Rabizadeh, S.3
-
235
-
-
0031773432
-
Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
-
Estevez A.G., Spear N., Manuel S.M., et al. Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Prog Brain Res 118 (1998) 269-280
-
(1998)
Prog Brain Res
, vol.118
, pp. 269-280
-
-
Estevez, A.G.1
Spear, N.2
Manuel, S.M.3
-
237
-
-
0034662807
-
Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis
-
Stieber A., Gonatas J.O., and Gonatas N.K. Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis. J Neurol Sci 177 (2000) 114-123
-
(2000)
J Neurol Sci
, vol.177
, pp. 114-123
-
-
Stieber, A.1
Gonatas, J.O.2
Gonatas, N.K.3
-
238
-
-
0035664213
-
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
Watanabe M., Dykes-Hoberg M., Culotta V.C., et al. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiol Dis 8 (2001) 933-941
-
(2001)
Neurobiol Dis
, vol.8
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Culotta, V.C.3
-
239
-
-
0036212119
-
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading
-
Subramaniam J.R., Lyons W.E., Liu J., et al. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nat Neurosci 5 (2002) 301-307
-
(2002)
Nat Neurosci
, vol.5
, pp. 301-307
-
-
Subramaniam, J.R.1
Lyons, W.E.2
Liu, J.3
-
240
-
-
0030862630
-
The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Hottinger A.F., Fine E.G., Gurney M.E., et al. The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. Eur J Neurosci 9 (1997) 1548-1551
-
(1997)
Eur J Neurosci
, vol.9
, pp. 1548-1551
-
-
Hottinger, A.F.1
Fine, E.G.2
Gurney, M.E.3
-
241
-
-
0033597218
-
Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice
-
Nagano S., Ogawa Y., Yanagihara T., and Sakoda S. Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice. Neurosci Lett 265 (1999) 159-162
-
(1999)
Neurosci Lett
, vol.265
, pp. 159-162
-
-
Nagano, S.1
Ogawa, Y.2
Yanagihara, T.3
Sakoda, S.4
-
242
-
-
0035068202
-
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
-
Andreassen O.A., Dedeoglu A., Friedlich A., et al. Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp Neurol 168 (2001) 419-424
-
(2001)
Exp Neurol
, vol.168
, pp. 419-424
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Friedlich, A.3
-
243
-
-
0029040463
-
Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis
-
Louwerse E.S., Weverling G.J., Bossuyt P.M., et al. Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch Neurol 52 (1995) 559-564
-
(1995)
Arch Neurol
, vol.52
, pp. 559-564
-
-
Louwerse, E.S.1
Weverling, G.J.2
Bossuyt, P.M.3
-
244
-
-
0033594249
-
The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis
-
Cudkowicz M.E., Sexton P.M., Ellis T., et al. The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis. Neurology 52 (1999) 1492-1494
-
(1999)
Neurology
, vol.52
, pp. 1492-1494
-
-
Cudkowicz, M.E.1
Sexton, P.M.2
Ellis, T.3
-
245
-
-
0028347114
-
An open-randomized clinical trial of selegiline in amyotrophic lateral sclerosis
-
Mazzini L., Testa D., Balzarini C., and Mora G. An open-randomized clinical trial of selegiline in amyotrophic lateral sclerosis. J Neurol 241 (1994) 223-227
-
(1994)
J Neurol
, vol.241
, pp. 223-227
-
-
Mazzini, L.1
Testa, D.2
Balzarini, C.3
Mora, G.4
-
246
-
-
0024982151
-
Clinical trial of the treatment of amyotrophic lateral sclerosis with bromocriptine [in Polish]
-
Szulc-Kuberska J., Klimek A., Stepien H., and Woszczak M. Clinical trial of the treatment of amyotrophic lateral sclerosis with bromocriptine [in Polish]. Neurol Neurochir Pol 24 (1990) 37-41
-
(1990)
Neurol Neurochir Pol
, vol.24
, pp. 37-41
-
-
Szulc-Kuberska, J.1
Klimek, A.2
Stepien, H.3
Woszczak, M.4
-
247
-
-
0029787291
-
Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants
-
Vyth A., Timmer J.G., Bossuyt P.M., et al. Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants. J Neurol Sci 139 suppl (1996) 99-103
-
(1996)
J Neurol Sci
, vol.139
, Issue.SUPPL
, pp. 99-103
-
-
Vyth, A.1
Timmer, J.G.2
Bossuyt, P.M.3
-
248
-
-
0036771852
-
10 in early Parkinson disease: evidence of slowing of the functional decline
-
10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol 59 (2002) 1541-1550
-
(2002)
Arch Neurol
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
-
249
-
-
0036525567
-
10 as a possible treatment for neurodegenerative diseases
-
10 as a possible treatment for neurodegenerative diseases. Free Radic Res 36 (2002) 455-460
-
(2002)
Free Radic Res
, vol.36
, pp. 455-460
-
-
Beal, M.F.1
-
250
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
Bowling A.C., Schulz J.B., Brown Jr. R.H., and Beal M.F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem 61 (1993) 2322-2325
-
(1993)
J Neurochem
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown Jr., R.H.3
Beal, M.F.4
-
251
-
-
0033624419
-
Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease
-
Albers D.S., and Beal M.F. Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. J Neural Transm Suppl 59 (2000) 133-154
-
(2000)
J Neural Transm Suppl
, vol.59
, pp. 133-154
-
-
Albers, D.S.1
Beal, M.F.2
-
252
-
-
0034864628
-
Apoptosis in amyotrophic lateral sclerosis: a review of the evidence
-
Sathasivam S., Ince P.G., and Shaw P.J. Apoptosis in amyotrophic lateral sclerosis: a review of the evidence. Neuropathol Appl Neurobiol 27 (2001) 257-274
-
(2001)
Neuropathol Appl Neurobiol
, vol.27
, pp. 257-274
-
-
Sathasivam, S.1
Ince, P.G.2
Shaw, P.J.3
-
253
-
-
0029563461
-
Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus
-
Troost D., Aten J., Morsink F., and de Jong J.M. Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus. Neuropathol Appl Neurobiol 21 (1995) 498-504
-
(1995)
Neuropathol Appl Neurobiol
, vol.21
, pp. 498-504
-
-
Troost, D.1
Aten, J.2
Morsink, F.3
de Jong, J.M.4
-
254
-
-
0032896327
-
Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism
-
Martin L.J. Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism. J Neuropathol Exp Neurol 58 (1999) 459-471
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 459-471
-
-
Martin, L.J.1
-
255
-
-
0034012013
-
The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis
-
Pedersen W.A., Luo H., Kruman I., et al. The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis. FASEB J 14 (2000) 913-924
-
(2000)
FASEB J
, vol.14
, pp. 913-924
-
-
Pedersen, W.A.1
Luo, H.2
Kruman, I.3
-
256
-
-
0030756459
-
Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Kostic V., Jackson-Lewis V., de Bilbao F., et al. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277 (1997) 559-562
-
(1997)
Science
, vol.277
, pp. 559-562
-
-
Kostic, V.1
Jackson-Lewis, V.2
de Bilbao, F.3
-
257
-
-
0032430185
-
Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
-
Pasinelli P., Borchelt D.R., Houseweart M.K., et al. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci USA 95 (1998) 15763-15768
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15763-15768
-
-
Pasinelli, P.1
Borchelt, D.R.2
Houseweart, M.K.3
-
258
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
Li M., Ona V.O., Guegan C., et al. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288 (2000) 335-339
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
-
259
-
-
0034998271
-
Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
-
Sanchez Mejia R.O., Ona V.O., Li M., and Friedlander R.M. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery 48 (2001) 1393-1399
-
(2001)
Neurosurgery
, vol.48
, pp. 1393-1399
-
-
Sanchez Mejia, R.O.1
Ona, V.O.2
Li, M.3
Friedlander, R.M.4
-
260
-
-
0037007645
-
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
-
Zhu S., Stavrovskaya I.G., Drozda M., et al. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417 (2002) 74-78
-
(2002)
Nature
, vol.417
, pp. 74-78
-
-
Zhu, S.1
Stavrovskaya, I.G.2
Drozda, M.3
-
261
-
-
0036406903
-
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis
-
Kriz J., Nguyen M., and Julien J. Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 10 (2002) 268
-
(2002)
Neurobiol Dis
, vol.10
, pp. 268
-
-
Kriz, J.1
Nguyen, M.2
Julien, J.3
-
262
-
-
0037067009
-
Minocycline delays disease onset and mortality in a transgenic model of ALS
-
Van Den B.L., Tilkin P., Lemmens G., and Robberecht W. Minocycline delays disease onset and mortality in a transgenic model of ALS. Neuroreport 13 (2002) 1067-1070
-
(2002)
Neuroreport
, vol.13
, pp. 1067-1070
-
-
Van Den, B.L.1
Tilkin, P.2
Lemmens, G.3
Robberecht, W.4
-
263
-
-
0035107442
-
Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals
-
Asanuma M., Nishibayashi-Asanuma S., Miyazaki I., et al. Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals. J Neurochem 76 (2001) 1895-1904
-
(2001)
J Neurochem
, vol.76
, pp. 1895-1904
-
-
Asanuma, M.1
Nishibayashi-Asanuma, S.2
Miyazaki, I.3
-
264
-
-
0033694033
-
Cyclooxygenases in the central nervous system: implications for treatment of neurological disorders
-
Yermakova A., and O'Banion M.K. Cyclooxygenases in the central nervous system: implications for treatment of neurological disorders. Curr Pharm Des 6 (2000) 1755-1776
-
(2000)
Curr Pharm Des
, vol.6
, pp. 1755-1776
-
-
Yermakova, A.1
O'Banion, M.K.2
-
265
-
-
0035949799
-
Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy
-
Yasojima K., Tourtellotte W.W., McGeer E.G., and McGeer P.L. Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy. Neurology 57 (2001) 952-956
-
(2001)
Neurology
, vol.57
, pp. 952-956
-
-
Yasojima, K.1
Tourtellotte, W.W.2
McGeer, E.G.3
McGeer, P.L.4
-
266
-
-
0033762974
-
Inhibition of cyclooxygenase-2 protects motor neurons in an organ-otypic model of amyotrophic lateral sclerosis
-
Drachman D.B., and Rothstein J.D. Inhibition of cyclooxygenase-2 protects motor neurons in an organ-otypic model of amyotrophic lateral sclerosis. Ann Neurol 48 (2000) 792-795
-
(2000)
Ann Neurol
, vol.48
, pp. 792-795
-
-
Drachman, D.B.1
Rothstein, J.D.2
-
267
-
-
0034889654
-
Modulation of NMDA-mediated excitotoxicity by protein kinase C
-
Wagey R., Hu J., Pelech S.L., et al. Modulation of NMDA-mediated excitotoxicity by protein kinase C. J Neurochem 78 (2001) 715-726
-
(2001)
J Neurochem
, vol.78
, pp. 715-726
-
-
Wagey, R.1
Hu, J.2
Pelech, S.L.3
-
268
-
-
0033830726
-
A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C
-
Noh K.M., Hwang J.Y., Shin H.C., and Koh J.Y. A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C. Neurobiol Dis 7 (2000) 375-383
-
(2000)
Neurobiol Dis
, vol.7
, pp. 375-383
-
-
Noh, K.M.1
Hwang, J.Y.2
Shin, H.C.3
Koh, J.Y.4
-
269
-
-
0036225488
-
Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C
-
Schwartz Z., Sylvia V.L., Guinee T., et al. Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C. J Steroid Biochem Mol Biol 80 (2002) 401-410
-
(2002)
J Steroid Biochem Mol Biol
, vol.80
, pp. 401-410
-
-
Schwartz, Z.1
Sylvia, V.L.2
Guinee, T.3
-
270
-
-
0036258072
-
Pentoxifylline reduces biochemical markers of ischemiareperfusion induced spinal cord injury in rabbits
-
Savas S., Delibas N., Savas C., et al. Pentoxifylline reduces biochemical markers of ischemiareperfusion induced spinal cord injury in rabbits. Spinal Cord 40 (2002) 224-229
-
(2002)
Spinal Cord
, vol.40
, pp. 224-229
-
-
Savas, S.1
Delibas, N.2
Savas, C.3
-
271
-
-
0004707907
-
Glycocyamine and betaine in motor-neurone disease
-
Liversedge L.A. Glycocyamine and betaine in motor-neurone disease. Lancet (1956) 1136-1138
-
(1956)
Lancet
, pp. 1136-1138
-
-
Liversedge, L.A.1
-
272
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi P., Ferrante R.J., Matthews R.T., et al. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med 5 (1999) 347-350
-
(1999)
Nat Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
-
273
-
-
0034208612
-
Oral administration of creatine monohydrate retards progression of motor neuron disease in the wobbler mouse
-
Ikeda K., Iwasaki Y., and Kinoshita M. Oral administration of creatine monohydrate retards progression of motor neuron disease in the wobbler mouse. Amyotroph Lateral Scler Other Motor Neuron Disord 1 (2000) 207-212
-
(2000)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, pp. 207-212
-
-
Ikeda, K.1
Iwasaki, Y.2
Kinoshita, M.3
-
274
-
-
0028951422
-
The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition
-
Earnest C.P., Snell P.G., Rodriguez R., et al. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 153 (1995) 207-209
-
(1995)
Acta Physiol Scand
, vol.153
, pp. 207-209
-
-
Earnest, C.P.1
Snell, P.G.2
Rodriguez, R.3
-
275
-
-
0033541016
-
Creatine monohydrate increases strength in patients with neuromuscular disease
-
Tarnopolsky M., and Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology 52 (1999) 854-857
-
(1999)
Neurology
, vol.52
, pp. 854-857
-
-
Tarnopolsky, M.1
Martin, J.2
-
277
-
-
0035991271
-
No effect of creatine on respiratory distress in amyotrophic lateral sclerosis
-
Drory V.E., and Gross D. No effect of creatine on respiratory distress in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 3 (2002) 43-46
-
(2002)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.3
, pp. 43-46
-
-
Drory, V.E.1
Gross, D.2
-
278
-
-
0004679042
-
Treatment of amyotrophic lateral sclerosis with vitamin E (alphatocopherol)
-
Denker P.G., and Scheinman L. Treatment of amyotrophic lateral sclerosis with vitamin E (alphatocopherol). JAMA 116 (1941) 1893-1895
-
(1941)
JAMA
, vol.116
, pp. 1893-1895
-
-
Denker, P.G.1
Scheinman, L.2
-
279
-
-
0035007860
-
A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzoletocopherol Study Group
-
Desnuelle C., Dib M., Garrel C., and Favier A. A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzoletocopherol Study Group. Amyotroph Lateral Scler Other Motor Neuron Disord 2 (2001) 9-18
-
(2001)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.2
, pp. 9-18
-
-
Desnuelle, C.1
Dib, M.2
Garrel, C.3
Favier, A.4
-
280
-
-
0036751978
-
A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes
-
Esposito E., Rotilio D., Di M., et al. A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiol Aging 23 (2002) 719
-
(2002)
Neurobiol Aging
, vol.23
, pp. 719
-
-
Esposito, E.1
Rotilio, D.2
Di, M.3
-
281
-
-
0035988588
-
Vitamin E and neurodegenerative disorders associated with oxidative stress
-
Butterfield D.A., Castegna A., Drake J., et al. Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutr Neurosci 5 (2002) 229-239
-
(2002)
Nutr Neurosci
, vol.5
, pp. 229-239
-
-
Butterfield, D.A.1
Castegna, A.2
Drake, J.3
-
282
-
-
0031827051
-
Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation
-
Apostolski S., Marinkovic Z., Nikolic A., et al. Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation. J Environ Pathol Toxicol Oncol 17 (1998) 325-329
-
(1998)
J Environ Pathol Toxicol Oncol
, vol.17
, pp. 325-329
-
-
Apostolski, S.1
Marinkovic, Z.2
Nikolic, A.3
-
283
-
-
0022518578
-
Trial of octacosanol in amyotrophic lateral sclerosis
-
Norris F.H., Denys E.H., and Fallat R.J. Trial of octacosanol in amyotrophic lateral sclerosis. Neurology 36 (1986) 1263-1264
-
(1986)
Neurology
, vol.36
, pp. 1263-1264
-
-
Norris, F.H.1
Denys, E.H.2
Fallat, R.J.3
-
284
-
-
0031761315
-
Effect of ultrahigh-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study
-
Kaji R., Kodama M., Imamura A., et al. Effect of ultrahigh-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study. Muscle Nerve 21 (1998) 1775-1778
-
(1998)
Muscle Nerve
, vol.21
, pp. 1775-1778
-
-
Kaji, R.1
Kodama, M.2
Imamura, A.3
-
285
-
-
0028308131
-
Ceftriaxone in amyotrophic lateral sclerosis
-
Norris F.H. Ceftriaxone in amyotrophic lateral sclerosis. Arch Neurol 51 (1994) 447
-
(1994)
Arch Neurol
, vol.51
, pp. 447
-
-
Norris, F.H.1
-
286
-
-
0028089648
-
Report of six sporadic cases of ALS patients receiving ceftriaxone
-
Couratier P., Vallat J.M., Merle L., et al. Report of six sporadic cases of ALS patients receiving ceftriaxone. Therapie 49 (1994) 146
-
(1994)
Therapie
, vol.49
, pp. 146
-
-
Couratier, P.1
Vallat, J.M.2
Merle, L.3
-
287
-
-
0017292962
-
Virological studies of amyotrophic lateral sclerosis: an overview
-
Johnson R.T. Virological studies of amyotrophic lateral sclerosis: an overview. UCLA Forum Med Sci (1976) 173-180
-
(1976)
UCLA Forum Med Sci
, pp. 173-180
-
-
Johnson, R.T.1
-
289
-
-
0026706840
-
Motor neuron diseases and viruses: poliovirus, retroviruses, and lymphomas
-
Jubelt B. Motor neuron diseases and viruses: poliovirus, retroviruses, and lymphomas. Curr Opin Neurol Neurosurg 5 (1992) 655-658
-
(1992)
Curr Opin Neurol Neurosurg
, vol.5
, pp. 655-658
-
-
Jubelt, B.1
-
290
-
-
0033971937
-
Viral hide-and-seek in sporadic ALS: a new challenge
-
Karpati G., and Dalakas M.C. Viral hide-and-seek in sporadic ALS: a new challenge. Neurology 54 (2000) 6-7
-
(2000)
Neurology
, vol.54
, pp. 6-7
-
-
Karpati, G.1
Dalakas, M.C.2
-
291
-
-
0035949784
-
Does viral disease underlie ALS? Lessons from the AIDS pandemic
-
Jubelt B., and Berger J.R. Does viral disease underlie ALS? Lessons from the AIDS pandemic. Neurology 57 (2001) 945-946
-
(2001)
Neurology
, vol.57
, pp. 945-946
-
-
Jubelt, B.1
Berger, J.R.2
-
292
-
-
0018292061
-
Failure to detect poliovirus genetic information in amyotrophic lateral sclerosis
-
Viola M.V., Myers J.C., Gann K.L., et al. Failure to detect poliovirus genetic information in amyotrophic lateral sclerosis. Ann Neurol 5 (1979) 402-403
-
(1979)
Ann Neurol
, vol.5
, pp. 402-403
-
-
Viola, M.V.1
Myers, J.C.2
Gann, K.L.3
-
293
-
-
0018869390
-
Amyotrophic lateral sclerosis: search for poliovirus by nucleic acid hybridization
-
Miller J.R., Guntaka R.V., and Myers J.C. Amyotrophic lateral sclerosis: search for poliovirus by nucleic acid hybridization. Neurology 30 (1980) 884-886
-
(1980)
Neurology
, vol.30
, pp. 884-886
-
-
Miller, J.R.1
Guntaka, R.V.2
Myers, J.C.3
-
294
-
-
0019778574
-
Virus detection by nucleic acid hybridization: examination of normal and ALS tissues for the presence of poliovirus
-
Kohne D.E., Gibbs C.J., White L., et al. Virus detection by nucleic acid hybridization: examination of normal and ALS tissues for the presence of poliovirus. J Gen Virol 56 pt 2 (1981) 223-233
-
(1981)
J Gen Virol
, vol.56
, Issue.PART 2
, pp. 223-233
-
-
Kohne, D.E.1
Gibbs, C.J.2
White, L.3
-
295
-
-
0021869321
-
Detection of picornavirus sequences in nervous tissue of amyotrophic lateral sclerosis and control patients
-
Brahic M., Smith R.A., Gibbs Jr. C.J., et al. Detection of picornavirus sequences in nervous tissue of amyotrophic lateral sclerosis and control patients. Ann Neurol 18 (1985) 337-343
-
(1985)
Ann Neurol
, vol.18
, pp. 337-343
-
-
Brahic, M.1
Smith, R.A.2
Gibbs Jr., C.J.3
-
296
-
-
0024439527
-
Enteroviral-related antigen in circulating immune complexes of amyotrophic lateral sclerosis patients
-
Bartfeld H., Dham C., Donnenfeld H., et al. Enteroviral-related antigen in circulating immune complexes of amyotrophic lateral sclerosis patients. Intervirology 30 (1989) 202-212
-
(1989)
Intervirology
, vol.30
, pp. 202-212
-
-
Bartfeld, H.1
Dham, C.2
Donnenfeld, H.3
-
297
-
-
0028811503
-
Search for persistent infection with poliovirus or other enteroviruses in amyotrophic lateral sclerosis-motor neurone disease
-
Swanson N.R., Fox S.A., and Mastaglia F.L. Search for persistent infection with poliovirus or other enteroviruses in amyotrophic lateral sclerosis-motor neurone disease. Neuromusc Disord 5 (1995) 457-465
-
(1995)
Neuromusc Disord
, vol.5
, pp. 457-465
-
-
Swanson, N.R.1
Fox, S.A.2
Mastaglia, F.L.3
-
298
-
-
0033981056
-
Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS
-
Berger M.M., Kopp N., Vital C., et al. Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS. Neurology 54 (2000) 20-25
-
(2000)
Neurology
, vol.54
, pp. 20-25
-
-
Berger, M.M.1
Kopp, N.2
Vital, C.3
-
299
-
-
0033923528
-
Detection of reverse transcriptase activity in the serum of patients with motor neurone disease
-
Andrews W.D., Tuke P.W., Al Chalabi A., et al. Detection of reverse transcriptase activity in the serum of patients with motor neurone disease. J Med Virol 61 (2000) 527-532
-
(2000)
J Med Virol
, vol.61
, pp. 527-532
-
-
Andrews, W.D.1
Tuke, P.W.2
Al Chalabi, A.3
-
300
-
-
85086348708
-
Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS
-
Pamphlett R. Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS. Neurology 55 (2000) 1420-1421
-
(2000)
Neurology
, vol.55
, pp. 1420-1421
-
-
Pamphlett, R.1
-
301
-
-
0035132168
-
Absence of echovirus sequences in brain and spinal cord of amyotrophic lateral sclerosis patients
-
Walker M.P., Schlaberg R., Hays A.P., et al. Absence of echovirus sequences in brain and spinal cord of amyotrophic lateral sclerosis patients. Ann Neurol 49 (2001) 249-253
-
(2001)
Ann Neurol
, vol.49
, pp. 249-253
-
-
Walker, M.P.1
Schlaberg, R.2
Hays, A.P.3
-
302
-
-
0035954354
-
Detection of enteroviral sequences from frozen spinal cord samples of Japanese ALS patients
-
Giraud P., Beaulieux F., Ono S., et al. Detection of enteroviral sequences from frozen spinal cord samples of Japanese ALS patients. Neurology 56 (2001) 1777-1778
-
(2001)
Neurology
, vol.56
, pp. 1777-1778
-
-
Giraud, P.1
Beaulieux, F.2
Ono, S.3
-
303
-
-
0036175344
-
New insights into the viral theory of amyotrophic lateral sclerosis: study on the possible role of Kaposi's sarcoma-associated virus/human herpesvirus 8
-
Sola P., Bedin R., Casoni F., et al. New insights into the viral theory of amyotrophic lateral sclerosis: study on the possible role of Kaposi's sarcoma-associated virus/human herpesvirus 8. Eur Neurol 47 (2002) 108-112
-
(2002)
Eur Neurol
, vol.47
, pp. 108-112
-
-
Sola, P.1
Bedin, R.2
Casoni, F.3
-
304
-
-
0015128099
-
The use of isoprinosine in patients with amyotrophic lateral sclerosis
-
Fareed G.C., and Tyler H.R. The use of isoprinosine in patients with amyotrophic lateral sclerosis. Neurology 21 (1971) 937-940
-
(1971)
Neurology
, vol.21
, pp. 937-940
-
-
Fareed, G.C.1
Tyler, H.R.2
-
305
-
-
0019453541
-
Amantadine and guanidine are ineffective in ALS
-
Munsat T.L., Easterday C.S., Levy S., et al. Amantadine and guanidine are ineffective in ALS. Neurology 31 (1981) 1054-1055
-
(1981)
Neurology
, vol.31
, pp. 1054-1055
-
-
Munsat, T.L.1
Easterday, C.S.2
Levy, S.3
-
306
-
-
0018075269
-
Therapeutic trial of tilorone in ALS: lack of benefit in a double-blind, placebo-controlled study
-
Olson W.H., Simons J.A., and Halaas G.W. Therapeutic trial of tilorone in ALS: lack of benefit in a double-blind, placebo-controlled study. Neurology 28 (1978) 1293-1295
-
(1978)
Neurology
, vol.28
, pp. 1293-1295
-
-
Olson, W.H.1
Simons, J.A.2
Halaas, G.W.3
-
307
-
-
0026328104
-
Low-molecular transfer factor and its use in the treatment of amyotrophic lateral sclerosis [in Czech]
-
Nevsimal O., Pekarek J., Koubek K., et al. Low-molecular transfer factor and its use in the treatment of amyotrophic lateral sclerosis [in Czech]. Cesk Neurol Neurochir 54 (1991) 220-222
-
(1991)
Cesk Neurol Neurochir
, vol.54
, pp. 220-222
-
-
Nevsimal, O.1
Pekarek, J.2
Koubek, K.3
-
309
-
-
0035949791
-
An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy
-
MacGowan D.J., Scelsa S.N., and Waldron M. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 57 (2001) 1094-1097
-
(2001)
Neurology
, vol.57
, pp. 1094-1097
-
-
MacGowan, D.J.1
Scelsa, S.N.2
Waldron, M.3
-
310
-
-
0035852960
-
Treatment of ALS with pleconaril
-
Ansevin C.F. Treatment of ALS with pleconaril. Neurology 56 (2001) 691-692
-
(2001)
Neurology
, vol.56
, pp. 691-692
-
-
Ansevin, C.F.1
-
311
-
-
0015166920
-
Amyotrophic lateral sclerosis: metabolism of central monoamines and treatment with l-dopa
-
Mendell J.R., Chase T.N., and Engel W.K. Amyotrophic lateral sclerosis: metabolism of central monoamines and treatment with l-dopa. Trans Am Neurol Assoc 96 (1971) 284-286
-
(1971)
Trans Am Neurol Assoc
, vol.96
, pp. 284-286
-
-
Mendell, J.R.1
Chase, T.N.2
Engel, W.K.3
-
312
-
-
0029248104
-
A clinical trial of therapeutic electrical stimulation for amyotrophic lateral sclerosis
-
Handa I., Matsushita N., Ihashi K., et al. A clinical trial of therapeutic electrical stimulation for amyotrophic lateral sclerosis. Tohoku J Exp Med 175 (1995) 123-134
-
(1995)
Tohoku J Exp Med
, vol.175
, pp. 123-134
-
-
Handa, I.1
Matsushita, N.2
Ihashi, K.3
-
313
-
-
0018677971
-
Trial of baclofen in amyotrophic lateral sclerosis
-
Norris Jr. F.H., Sachais B., and Carey M. Trial of baclofen in amyotrophic lateral sclerosis. Arch Neurol 36 (1979) 715-716
-
(1979)
Arch Neurol
, vol.36
, pp. 715-716
-
-
Norris Jr., F.H.1
Sachais, B.2
Carey, M.3
-
314
-
-
0022491862
-
Cholinesterase inhibitors lack therapeutic effect in amyotrophic lateral sclerosis. A controlled study of physostigmine versus neostigmine
-
Aquilonius S.M., Askmark H., Eckernas S.A., et al. Cholinesterase inhibitors lack therapeutic effect in amyotrophic lateral sclerosis. A controlled study of physostigmine versus neostigmine. Acta Neurol Scand 73 (1986) 628-632
-
(1986)
Acta Neurol Scand
, vol.73
, pp. 628-632
-
-
Aquilonius, S.M.1
Askmark, H.2
Eckernas, S.A.3
-
315
-
-
0029973271
-
A double-blind placebo-controlled study of 3,4-diaminopyridine in amyotrophic lateral sclerosis patients on a rehabilitation unit
-
Aisen M.L., Sevilla D., Edelstein L., and Blass J. A double-blind placebo-controlled study of 3,4-diaminopyridine in amyotrophic lateral sclerosis patients on a rehabilitation unit. J Neurol Sci 138 (1996) 93-96
-
(1996)
J Neurol Sci
, vol.138
, pp. 93-96
-
-
Aisen, M.L.1
Sevilla, D.2
Edelstein, L.3
Blass, J.4
-
316
-
-
0025170048
-
Functional and pharmacokinetic studies of tetrahydroaminoacridine in patients with amyotrophic lateral sclerosis
-
Askmark H., Aquilonius S.M., Gillberg P.G., et al. Functional and pharmacokinetic studies of tetrahydroaminoacridine in patients with amyotrophic lateral sclerosis. Acta Neurol Scand 82 (1990) 253-258
-
(1990)
Acta Neurol Scand
, vol.82
, pp. 253-258
-
-
Askmark, H.1
Aquilonius, S.M.2
Gillberg, P.G.3
-
317
-
-
0035838427
-
Clinical implications of the genetics of ALS and other motor neuron diseases
-
Orrell R.W., and Figlewicz D.A. Clinical implications of the genetics of ALS and other motor neuron diseases. Neurology 57 (2001) 9-17
-
(2001)
Neurology
, vol.57
, pp. 9-17
-
-
Orrell, R.W.1
Figlewicz, D.A.2
-
318
-
-
0034790894
-
Genetic inroads in familial ALS
-
Shaw P.J. Genetic inroads in familial ALS. Nat Genet 29 (2001) 103-104
-
(2001)
Nat Genet
, vol.29
, pp. 103-104
-
-
Shaw, P.J.1
-
319
-
-
0033487112
-
ALSO Database: database of SOD1 (and other) gene mutations in ALS on the Internet. European FALS Group and ALSOD Consortium
-
Radunovic A., and Leigh P.N. ALSO Database: database of SOD1 (and other) gene mutations in ALS on the Internet. European FALS Group and ALSOD Consortium. Amyotroph Lateral Scler Other Motor Neuron Disord 1 (1999) 45-49
-
(1999)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, pp. 45-49
-
-
Radunovic, A.1
Leigh, P.N.2
-
320
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S., Hand C.K., Osuga H., et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 29 (2001) 166-173
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
-
321
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang Y., Hentati A., Deng H.X., et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet 29 (2001) 160-165
-
(2001)
Nat Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
-
322
-
-
0036821464
-
Hereditary motor neuron disease caused by mutations in the ALS2 gene: "The long and the short of it."
-
Leavitt B. Hereditary motor neuron disease caused by mutations in the ALS2 gene: "The long and the short of it.". Clin Genet 62 (2002) 265
-
(2002)
Clin Genet
, vol.62
, pp. 265
-
-
Leavitt, B.1
-
323
-
-
0141568940
-
Variants in the ALS2 gene are not associated with sporadic amyotrophic lateral sclerosis
-
(in press).
-
A1-Chalabi A., Hansen V.K., Simpson C.L., et al. Variants in the ALS2 gene are not associated with sporadic amyotrophic lateral sclerosis. Neurogenetics (2003) (in press).
-
(2003)
Neurogenetics
-
-
A1-Chalabi, A.1
Hansen, V.K.2
Simpson, C.L.3
-
324
-
-
0032414948
-
Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers
-
Hentati A., Ouahchi K., Pericak-Vance M.A., et al. Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers. Neurogenetics 2 (1998) 55-60
-
(1998)
Neurogenetics
, vol.2
, pp. 55-60
-
-
Hentati, A.1
Ouahchi, K.2
Pericak-Vance, M.A.3
-
325
-
-
0031959591
-
Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34
-
Chance P.F., Rabin B.A., Ryan S.G., et al. Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34. Am J Hum Genet 62 (1998) 633-640
-
(1998)
Am J Hum Genet
, vol.62
, pp. 633-640
-
-
Chance, P.F.1
Rabin, B.A.2
Ryan, S.G.3
-
326
-
-
0034605478
-
Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22
-
Hosler B.A., Siddique T., Sapp P.C., et al. Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22. JAMA 284 (2000) 1664-1669
-
(2000)
JAMA
, vol.284
, pp. 1664-1669
-
-
Hosler, B.A.1
Siddique, T.2
Sapp, P.C.3
-
327
-
-
18244393223
-
A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q
-
Hand C.K., Khoris J., Salachas F., et al. A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q. Am J Hum Genet 70 (2002) 251-256
-
(2002)
Am J Hum Genet
, vol.70
, pp. 251-256
-
-
Hand, C.K.1
Khoris, J.2
Salachas, F.3
-
328
-
-
0041664055
-
Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q
-
(in press).
-
Ruddy D.M., Parton M.J., Al-Chalabi, et al. Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q. Am J Hum Genet (2003) (in press).
-
(2003)
Am J Hum Genet
-
-
Ruddy, D.M.1
Parton, M.J.2
Al-Chalabi3
-
329
-
-
0033009789
-
Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis
-
Hayward C., Colville S., Swingler R.J., and Brock D.J. Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis. Neurology 52 (1999) 1899-1901
-
(1999)
Neurology
, vol.52
, pp. 1899-1901
-
-
Hayward, C.1
Colville, S.2
Swingler, R.J.3
Brock, D.J.4
-
330
-
-
0014336826
-
Proximal axonal enlargement in motor neuron disease
-
Carpenter S. Proximal axonal enlargement in motor neuron disease. Neurology 18 (1968) 841-851
-
(1968)
Neurology
, vol.18
, pp. 841-851
-
-
Carpenter, S.1
-
331
-
-
0021167918
-
Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis
-
Hirano A., Donnenfeld H., Sasaki S., and Nakano I. Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 43 (1984) 461-470
-
(1984)
J Neuropathol Exp Neurol
, vol.43
, pp. 461-470
-
-
Hirano, A.1
Donnenfeld, H.2
Sasaki, S.3
Nakano, I.4
-
332
-
-
0021157469
-
Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis
-
Hirano A., Nakano I., Kurland L.T., et al. Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 43 (1984) 471-480
-
(1984)
J Neuropathol Exp Neurol
, vol.43
, pp. 471-480
-
-
Hirano, A.1
Nakano, I.2
Kurland, L.T.3
-
333
-
-
0027410516
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
-
Xu Z., Cork L.C., Griffin J.W., and Cleveland D.W. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73 (1993) 23-33
-
(1993)
Cell
, vol.73
, pp. 23-33
-
-
Xu, Z.1
Cork, L.C.2
Griffin, J.W.3
Cleveland, D.W.4
-
334
-
-
0033366384
-
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
-
Williamson T.L., and Cleveland D.W. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat Neurosci 2 (1999) 50-56
-
(1999)
Nat Neurosci
, vol.2
, pp. 50-56
-
-
Williamson, T.L.1
Cleveland, D.W.2
-
335
-
-
0027465098
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis
-
Cote F., Collard J.F., and Julien J.P. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73 (1993) 35-46
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.F.2
Julien, J.P.3
-
336
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz D.A., Krizus A., Martinoli M.G., et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum Mol Genet 3 (1994) 1757-1761
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
-
337
-
-
0032926368
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis
-
Al-Chalabi A., Andersen P.M., Nilsson P., et al. Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum Mol Genet 8 (1999) 157-164
-
(1999)
Hum Mol Genet
, vol.8
, pp. 157-164
-
-
Al-Chalabi, A.1
Andersen, P.M.2
Nilsson, P.3
-
338
-
-
0032482976
-
Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant
-
Williamson T.L., Bruijn L.I., Zhu Q., Anderson K.L., et al. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc Natl Acad Sci USA 95 (1998) 9631-9636
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9631-9636
-
-
Williamson, T.L.1
Bruijn, L.I.2
Zhu, Q.3
Anderson, K.L.4
-
339
-
-
0032483016
-
Protective effect of neurofilament heavy gene over-expression in motor neuron disease induced by mutant superoxide dismutase
-
Couillard-Despres S., Zhu Q., Wong P.C., et al. Protective effect of neurofilament heavy gene over-expression in motor neuron disease induced by mutant superoxide dismutase. Proc Natl Acad Sci USA 95 (1998) 9626-9630
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9626-9630
-
-
Couillard-Despres, S.1
Zhu, Q.2
Wong, P.C.3
-
340
-
-
0033953140
-
Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis
-
Kong J., and Xu Z. Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis. Neurosci Lett 281 (2000) 72-74
-
(2000)
Neurosci Lett
, vol.281
, pp. 72-74
-
-
Kong, J.1
Xu, Z.2
-
341
-
-
0033230327
-
Late onset death of motor neurons in mice overexpressing wild-type peripherin
-
Beaulieu J.M., Nguyen M.D., and Julien J.P. Late onset death of motor neurons in mice overexpressing wild-type peripherin. J Cell Biol 147 (1999) 531-544
-
(1999)
J Cell Biol
, vol.147
, pp. 531-544
-
-
Beaulieu, J.M.1
Nguyen, M.D.2
Julien, J.P.3
-
342
-
-
0036310142
-
Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis
-
Menzies F.M., Cookson M.R., Taylor R.W., et al. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis. Brain 125 pt 7 (2002) 1522-1533
-
(2002)
Brain
, vol.125
, Issue.PART 7
, pp. 1522-1533
-
-
Menzies, F.M.1
Cookson, M.R.2
Taylor, R.W.3
-
343
-
-
0036176613
-
Mitochondrial involvement in amyotrophic lateral sclerosis
-
Menzies F.M., Ince P.G., and Shaw P.J. Mitochondrial involvement in amyotrophic lateral sclerosis. Neurochem Int 40 (2002) 543-551
-
(2002)
Neurochem Int
, vol.40
, pp. 543-551
-
-
Menzies, F.M.1
Ince, P.G.2
Shaw, P.J.3
-
344
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber S., Kunz D., Winkler K., et al. Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis. Brain 123 pt 7 (2000) 1339-1348
-
(2000)
Brain
, vol.123
, Issue.PART 7
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
-
345
-
-
0034601407
-
Mitochondrial DNA deletion mutation levels are elevated in ALS brains
-
Dhaliwal G.K., and Grewal R.P. Mitochondrial DNA deletion mutation levels are elevated in ALS brains. Neuroreport 11 (2000) 2507-2509
-
(2000)
Neuroreport
, vol.11
, pp. 2507-2509
-
-
Dhaliwal, G.K.1
Grewal, R.P.2
-
346
-
-
0034959802
-
Spinal muscular atrophy
-
Talbot K., and Davies K.E. Spinal muscular atrophy. Semin Neurol 21 (2001) 189-197
-
(2001)
Semin Neurol
, vol.21
, pp. 189-197
-
-
Talbot, K.1
Davies, K.E.2
-
347
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
Lefebvre S., Burglen L., Reboullet S., et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 80 (1995) 155-165
-
(1995)
Cell
, vol.80
, pp. 155-165
-
-
Lefebvre, S.1
Burglen, L.2
Reboullet, S.3
-
348
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy N., Mahadevan M.S., McLean M., et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80 (1995) 167-178
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
-
349
-
-
0036301711
-
Spinal muscular atrophy: recent advances and future prospects
-
Nicole S., Diaz C.C., Frugier T., and Melki J. Spinal muscular atrophy: recent advances and future prospects. Muscle Nerve 26 (2002) 4-13
-
(2002)
Muscle Nerve
, vol.26
, pp. 4-13
-
-
Nicole, S.1
Diaz, C.C.2
Frugier, T.3
Melki, J.4
-
350
-
-
0031044279
-
Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism?
-
Talbot K., Ponting C.P., Theodosiou A.M., et al. Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism?. Hum Mol Genet 6 (1997) 497-500
-
(1997)
Hum Mol Genet
, vol.6
, pp. 497-500
-
-
Talbot, K.1
Ponting, C.P.2
Theodosiou, A.M.3
-
351
-
-
0031759799
-
Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex
-
Talbot K., Miguel-Aliaga I., Mohaghegh P., et al. Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Hum Mol Genet 7 (1998) 2149-2156
-
(1998)
Hum Mol Genet
, vol.7
, pp. 2149-2156
-
-
Talbot, K.1
Miguel-Aliaga, I.2
Mohaghegh, P.3
-
352
-
-
0031442184
-
Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
-
Iwahashi H., Eguchi Y., Yasuhara N., et al. Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy. Nature 390 (1997) 413-417
-
(1997)
Nature
, vol.390
, pp. 413-417
-
-
Iwahashi, H.1
Eguchi, Y.2
Yasuhara, N.3
-
353
-
-
0030899577
-
The relationship of spinal muscular atrophy to motor neuron disease: investigation of SMN and NAIP gene deletions in sporadic and familial ALS
-
Orrell R.W., Habgood J.J., de Belleroche J.S., and Lane R.J. The relationship of spinal muscular atrophy to motor neuron disease: investigation of SMN and NAIP gene deletions in sporadic and familial ALS. J Neurol Sci 145 (1997) 55-61
-
(1997)
J Neurol Sci
, vol.145
, pp. 55-61
-
-
Orrell, R.W.1
Habgood, J.J.2
de Belleroche, J.S.3
Lane, R.J.4
-
354
-
-
0033058289
-
Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis
-
Parboosingh J.S., Meininger V., McKenna-Yasek D., et al. Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis. Arch Neurol 56 (1999) 710-712
-
(1999)
Arch Neurol
, vol.56
, pp. 710-712
-
-
Parboosingh, J.S.1
Meininger, V.2
McKenna-Yasek, D.3
-
355
-
-
0035957312
-
Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS
-
Veldink J.H., Van den Berg L.H., Cobben J.M., et al. Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS. Neurology 56 (2001) 749-752
-
(2001)
Neurology
, vol.56
, pp. 749-752
-
-
Veldink, J.H.1
Van den Berg, L.H.2
Cobben, J.M.3
-
356
-
-
0034955320
-
Progressive spastic paraparesis: hereditary spastic paraplegia and its relation to primary and amyotrophic lateral sclerosis
-
Fink J.K. Progressive spastic paraparesis: hereditary spastic paraplegia and its relation to primary and amyotrophic lateral sclerosis. Semin Neurol 21 (2001) 199-207
-
(2001)
Semin Neurol
, vol.21
, pp. 199-207
-
-
Fink, J.K.1
-
357
-
-
0032721512
-
Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia
-
Hazan J., Fonknechten N., Mavel D., et al. Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia. Nat Genet 23 (1999) 296-303
-
(1999)
Nat Genet
, vol.23
, pp. 296-303
-
-
Hazan, J.1
Fonknechten, N.2
Mavel, D.3
-
358
-
-
0028239867
-
X-linked spastic paraplegia and Pelizaeus-Merzbacher disease are allelic disorders at the proteolipid protein locus
-
Saugier-Veber P., Munnich A., Bonneau D., et al. X-linked spastic paraplegia and Pelizaeus-Merzbacher disease are allelic disorders at the proteolipid protein locus. Nat Genet 6 (1994) 257-262
-
(1994)
Nat Genet
, vol.6
, pp. 257-262
-
-
Saugier-Veber, P.1
Munnich, A.2
Bonneau, D.3
-
359
-
-
7344229372
-
Identification of novel L1CAM mutations using fluorescence-assisted mismatch analysis
-
Saugier-Veber P., Martin C., Le Meur N., et al. Identification of novel L1CAM mutations using fluorescence-assisted mismatch analysis. Hum Mutat 12 (1998) 259-266
-
(1998)
Hum Mutat
, vol.12
, pp. 259-266
-
-
Saugier-Veber, P.1
Martin, C.2
Le Meur, N.3
-
360
-
-
0032511186
-
Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease
-
Casari G., De Fusco M., Ciarmatori S., et al. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell 93 (1998) 973-983
-
(1998)
Cell
, vol.93
, pp. 973-983
-
-
Casari, G.1
De Fusco, M.2
Ciarmatori, S.3
-
361
-
-
0035370669
-
Molecular basis of inherited spastic paraplegias
-
Casari G., and Rugarli E. Molecular basis of inherited spastic paraplegias. Curr Opin Genet Dev 11 (2001) 336-342
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 336-342
-
-
Casari, G.1
Rugarli, E.2
-
362
-
-
0001519052
-
Hereditary (familial) spastic paraplegia: further clinical and pathological observations
-
Schwartz G.A., and Lui C.N. Hereditary (familial) spastic paraplegia: further clinical and pathological observations. AMA Arch Neurol Psychiatry 75 (1956) 144-162
-
(1956)
AMA Arch Neurol Psychiatry
, vol.75
, pp. 144-162
-
-
Schwartz, G.A.1
Lui, C.N.2
-
363
-
-
77957151562
-
Screening of FALS patients with wild-type SOD1 for mutations in the SPG4 gene that is linked to autosomal dominant hereditary spastic paraplegia
-
Smith B.N., and Shaw C.E. Screening of FALS patients with wild-type SOD1 for mutations in the SPG4 gene that is linked to autosomal dominant hereditary spastic paraplegia. Amyotroph Lateral Scler Other Motor Neuron Disord 3 suppl 2 (2002) 64
-
(2002)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.3
, Issue.SUPPL. 2
, pp. 64
-
-
Smith, B.N.1
Shaw, C.E.2
-
364
-
-
0014310582
-
Progressive proximal spinal and bulbar muscular atrophy of late onset: a sex-linked recessive trait
-
Kennedy W.R., Alter M., and Sung J.H. Progressive proximal spinal and bulbar muscular atrophy of late onset: a sex-linked recessive trait. Neurology 18 (1968) 671-680
-
(1968)
Neurology
, vol.18
, pp. 671-680
-
-
Kennedy, W.R.1
Alter, M.2
Sung, J.H.3
-
365
-
-
0025800526
-
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
-
La Spada A.R., Wilson E.M., Lubahn D.B., et al. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352 (1991) 77-79
-
(1991)
Nature
, vol.352
, pp. 77-79
-
-
La Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
-
366
-
-
0037119253
-
Effect on motor neuron survival in mutant SOD1 (G93A) transgenic mice by Bcl-2 expression using retrograde axonal transport of adenoviral vectors
-
Yamashita S., Mita S., Kato S., et al. Effect on motor neuron survival in mutant SOD1 (G93A) transgenic mice by Bcl-2 expression using retrograde axonal transport of adenoviral vectors. Neurosci Lett 328 (2002) 289-293
-
(2002)
Neurosci Lett
, vol.328
, pp. 289-293
-
-
Yamashita, S.1
Mita, S.2
Kato, S.3
-
367
-
-
0034783080
-
Lentiviral vectors for the treatment of neurodegenerative diseases
-
Martin-Rendon E., Azzouz M., and Mazarakis N.D. Lentiviral vectors for the treatment of neurodegenerative diseases. Curr Opin Mol Ther 3 (2001) 476-481
-
(2001)
Curr Opin Mol Ther
, vol.3
, pp. 476-481
-
-
Martin-Rendon, E.1
Azzouz, M.2
Mazarakis, N.D.3
-
368
-
-
0037178766
-
Neuroscience. Versatile cells against intractable diseases
-
Holden C. Neuroscience. Versatile cells against intractable diseases. Science 297 (2002) 500-502
-
(2002)
Science
, vol.297
, pp. 500-502
-
-
Holden, C.1
-
370
-
-
0035669496
-
Manipulation of neural precursors in situ: induction of neurogenesis in the neocortex of adult mice
-
Magavi S.S., and Macklis J.D. Manipulation of neural precursors in situ: induction of neurogenesis in the neocortex of adult mice. Neuropsychopharmacology 25 (2001) 816-835
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 816-835
-
-
Magavi, S.S.1
Macklis, J.D.2
-
371
-
-
0036234835
-
Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons
-
Song H.J., Stevens C.F., and Gage F.H. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat Neurosci 5 (2002) 438-445
-
(2002)
Nat Neurosci
, vol.5
, pp. 438-445
-
-
Song, H.J.1
Stevens, C.F.2
Gage, F.H.3
-
372
-
-
0037079996
-
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents
-
Gritti A., Bonfanti L., Doetsch F., et al. Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents. J Neurosci 22 (2002) 437-445
-
(2002)
J Neurosci
, vol.22
, pp. 437-445
-
-
Gritti, A.1
Bonfanti, L.2
Doetsch, F.3
-
373
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Wichterle H., Lieberam I., Porter J.A., and Jessell T.M. Directed differentiation of embryonic stem cells into motor neurons. Cell 110 (2002) 385-397
-
(2002)
Cell
, vol.110
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
374
-
-
84984771681
-
Transplanted neural stem cells are capable of engraftment and differentiation in transgenic mutant SOD1 mice
-
3.
-
Maragakis N.J., et al. Transplanted neural stem cells are capable of engraftment and differentiation in transgenic mutant SOD1 mice. Soc Neurosci Abstracts 26 (2000) 668 3.
-
(2000)
Soc Neurosci Abstracts
, vol.26
, pp. 668
-
-
Maragakis, N.J.1
-
375
-
-
0036218669
-
Positive effect of transplantation of hNT neurons (NTera 2/D1 cell-line) in a model of familial amyotrophic lateral sclerosis
-
Garbuzova-Davis S., Willing A.E., Milliken M., et al. Positive effect of transplantation of hNT neurons (NTera 2/D1 cell-line) in a model of familial amyotrophic lateral sclerosis. Exp Neurol 174 (2002) 169-180
-
(2002)
Exp Neurol
, vol.174
, pp. 169-180
-
-
Garbuzova-Davis, S.1
Willing, A.E.2
Milliken, M.3
-
376
-
-
0035804799
-
Stem cells step closer to the clinic: paralysis partially reversed in rats with ALS-like disease
-
Vastag B. Stem cells step closer to the clinic: paralysis partially reversed in rats with ALS-like disease. JAMA 285 (2001) 1691-1693
-
(2001)
JAMA
, vol.285
, pp. 1691-1693
-
-
Vastag, B.1
|