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Volumn 147, Issue 3, 1999, Pages 531-544

Late onset death of motor neurons in mice overexpressing wild-type peripherin

Author keywords

ALS; Motor neuron; Neurofilament; Peripherin; Transgenic

Indexed keywords

CYTOKINE; PERIPHERIN; SUPEROXIDE DISMUTASE; INTERMEDIATE FILAMENT PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN;

EID: 0033230327     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.147.3.531     Document Type: Article
Times cited : (204)

References (61)
  • 1
    • 0030698718 scopus 로고    scopus 로고
    • Heterodimeric associations between neuronal intermediate filament proteins
    • Athlan, E.S., and W.E. Mushynski. 1997. Heterodimeric associations between neuronal intermediate filament proteins. J. Biol. Chem. 272:31073-31078.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31073-31078
    • Athlan, E.S.1    Mushynski, W.E.2
  • 3
    • 0032809052 scopus 로고    scopus 로고
    • Interactions between peripherin and neurofilaments in cultured cells: Disruption of peripherin assembly by the NF-M and NF-H subunits
    • Beaulieu, J.M., J. Robertson, and J.P. Julien. 1999. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. Biochem. Cell Biol. 77:41-45.
    • (1999) Biochem. Cell Biol. , vol.77 , pp. 41-45
    • Beaulieu, J.M.1    Robertson, J.2    Julien, J.P.3
  • 5
    • 0019859395 scopus 로고
    • Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs
    • Brinster, R.L., H.Y. Chen, M. Trumbauer, A.W. Senear, R. Warren, and R.D. Palmiter. 1981. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell. 27:223-231.
    • (1981) Cell , vol.27 , pp. 223-231
    • Brinster, R.L.1    Chen, H.Y.2    Trumbauer, M.3    Senear, A.W.4    Warren, R.5    Palmiter, R.D.6
  • 6
    • 0024342197 scopus 로고
    • Selective distribution of the 57 kDa neural intermediate filament protein in the rat CNS
    • Brody, B.A., C.A. Ley, and L.M. Parysek. 1989. Selective distribution of the 57 kDa neural intermediate filament protein in the rat CNS. J. Neurosci. 9:2391-2401.
    • (1989) J. Neurosci. , vol.9 , pp. 2391-2401
    • Brody, B.A.1    Ley, C.A.2    Parysek, L.M.3
  • 7
    • 0032518162 scopus 로고    scopus 로고
    • Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter
    • Bruening, W., B. Giasson, W. Mushynski, and H.D. Durham. 1998. Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter. Nucleic Acids Res. 26:486-489.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 486-489
    • Bruening, W.1    Giasson, B.2    Mushynski, W.3    Durham, H.D.4
  • 10
    • 0014336826 scopus 로고
    • Proximal axonal enlargement in motor neuron disease
    • Carpenter, S. 1968. Proximal axonal enlargement in motor neuron disease. Neurology. 18:841-851.
    • (1968) Neurology , vol.18 , pp. 841-851
    • Carpenter, S.1
  • 11
    • 0027220073 scopus 로고
    • Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments
    • Ching, G.Y., and R.K.H. Liem. 1993. Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments. J. Cell Biol. 122:1323-1335.
    • (1993) J. Cell Biol. , vol.122 , pp. 1323-1335
    • Ching, G.Y.1    Liem, R.K.H.2
  • 12
    • 0033561167 scopus 로고    scopus 로고
    • Overexpression of alpha-internexin causes abnormal neurofilamentous accumulations and motor coordination deficits in transgenic mice
    • Ching, G.Y., C.L. Chien, R. Flores, and R.K. Liem. 1999. Overexpression of alpha-internexin causes abnormal neurofilamentous accumulations and motor coordination deficits in transgenic mice. J. Neurosci. 19:2974-2986.
    • (1999) J. Neurosci. , vol.19 , pp. 2974-2986
    • Ching, G.Y.1    Chien, C.L.2    Flores, R.3    Liem, R.K.4
  • 13
    • 0003049433 scopus 로고
    • Pathology of motor system disorder
    • P.N. Leigh and M. Swash, editors. Springer-Verlag, London
    • Chou, S.M. 1995. Pathology of motor system disorder. In Motor Neuron Disease: Biology and Management. P.N. Leigh and M. Swash, editors. Springer-Verlag, London. 53-92.
    • (1995) Motor Neuron Disease: Biology and Management , pp. 53-92
    • Chou, S.M.1
  • 14
    • 0026739393 scopus 로고
    • Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease
    • Corho, M., and A.P. Hays. 1992. Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease. J. Neuropathol. Exp. Neurol. 51: 531-537.
    • (1992) J. Neuropathol. Exp. Neurol. , vol.51 , pp. 531-537
    • Corho, M.1    Hays, A.P.2
  • 15
    • 0027465098 scopus 로고
    • Progressive neuropathy in transgenic mce expressing the human neurofilamen heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Côté, F., J.F. Collard, and J.-P. Julien. 1993. Progressive neuropathy in transgenic mce expressing the human neurofilamen heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell. 73:35-46.
    • (1993) Cell , vol.73 , pp. 35-46
    • Côté, F.1    Collard, J.F.2    Julien, J.-P.3
  • 16
    • 1842289165 scopus 로고    scopus 로고
    • Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L
    • Crow, J.P., Y.Z. Ye, M. Strong, M. Kirk, S. Barnes, and J.S. Beckman. 1997. Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L. J. Neurochem. 69:1945-1953.
    • (1997) J. Neurochem. , vol.69 , pp. 1945-1953
    • Crow, J.P.1    Ye, Y.Z.2    Strong, M.3    Kirk, M.4    Barnes, S.5    Beckman, J.S.6
  • 17
    • 0029086271 scopus 로고
    • Peripherin assembles into homopolymers in SW13 cells
    • Cui, C., P.J. Stambrook, and L.M. Parysek. 1995. Peripherin assembles into homopolymers in SW13 cells. J. Cell Sci. 108:3279-3284.
    • (1995) J. Cell Sci. , vol.108 , pp. 3279-3284
    • Cui, C.1    Stambrook, P.J.2    Parysek, L.M.3
  • 18
    • 0031838352 scopus 로고    scopus 로고
    • Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
    • Cummings, C.J., M.A. Mancini, B. Antalffy, D.B. DeFranco, H.T. Orr, H.Y. Zoghbi. 1998. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nature Genet. 19:148-154.
    • (1998) Nature Genet. , vol.19 , pp. 148-154
    • Cummings, C.J.1    Mancini, M.A.2    Antalffy, B.3    DeFranco, D.B.4    Orr, H.T.5    Zoghbi, H.Y.6
  • 19
    • 0027382277 scopus 로고
    • Peripherin expression in hippocampal neurons induced by muscle soluble factors
    • Djabali, K., A. Zissopoulou, M.J.D. Hoop, S.D. Georgatos, and C.G. Dotti. 1993. Peripherin expression in hippocampal neurons induced by muscle soluble factors. J. Cell Biol. 123:1197-1206.
    • (1993) J. Cell Biol. , vol.123 , pp. 1197-1206
    • Djabali, K.1    Zissopoulou, A.2    Hoop, M.J.D.3    Georgatos, S.D.4    Dotti, C.G.5
  • 20
    • 0025246192 scopus 로고
    • Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein NF-L during the development of the rat
    • Escurat, M., K. Djabali, M. Gumpel, F. Gros, and M.M. Portier. 1990. Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein NF-L during the development of the rat. J. Neurosci. 10:764-784.
    • (1990) J. Neurosci. , vol.10 , pp. 764-784
    • Escurat, M.1    Djabali, K.2    Gumpel, M.3    Gros, F.4    Portier, M.M.5
  • 21
    • 0032484934 scopus 로고    scopus 로고
    • Pathogenesis of two axonopathies does not require axonal neurofilaments
    • Eyer, J., D.W. Cleveland, P.C. Wong, and A.C. Peterson. 1998. Pathogenesis of two axonopathies does not require axonal neurofilaments. Nature. 391:584-587.
    • (1998) Nature , vol.391 , pp. 584-587
    • Eyer, J.1    Cleveland, D.W.2    Wong, P.C.3    Peterson, A.C.4
  • 22
    • 0020793569 scopus 로고
    • A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
    • Feinberg, A.P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
    • (1983) Anal. Biochem. , vol.132 , pp. 6-13
    • Feinberg, A.P.1    Vogelstein, B.2
  • 23
    • 0025323983 scopus 로고
    • Neuronal intermediate filaments in rat dorsal root ganglia: Differential distribution of peripherin and neurofilament protein immunoreactivity and effect of capsaicin
    • Ferri, G.L., A. Sabani, L. Abelli, J.M. Polak, D. Dahl, and M.M. Portier. 1990. Neuronal intermediate filaments in rat dorsal root ganglia: differential distribution of peripherin and neurofilament protein immunoreactivity and effect of capsaicin. Brain Res. 515:331-335.
    • (1990) Brain Res. , vol.515 , pp. 331-335
    • Ferri, G.L.1    Sabani, A.2    Abelli, L.3    Polak, J.M.4    Dahl, D.5    Portier, M.M.6
  • 24
    • 0030032994 scopus 로고    scopus 로고
    • Developmental regulation of two distinct neuronal phenotypes in rat dorsal root ganglia
    • Goldstein, M.E., P. Grant, S.B. House, D.B. Henken, and H. Gainer. 1996. Developmental regulation of two distinct neuronal phenotypes in rat dorsal root ganglia. Neuroscience. 71:243-258.
    • (1996) Neuroscience , vol.71 , pp. 243-258
    • Goldstein, M.E.1    Grant, P.2    House, S.B.3    Henken, D.B.4    Gainer, H.5
  • 26
    • 0028868385 scopus 로고
    • Translation initiation and assembly of peripherin in cultured cells
    • Ho, C.L., S.S.M. Chin, K. Carnevale, and R.K.H. Liem. 1995. Translation initiation and assembly of peripherin in cultured cells. Eur. J. Cell Biol. 68:103-112.
    • (1995) Eur. J. Cell Biol. , vol.68 , pp. 103-112
    • Ho, C.L.1    Chin, S.S.M.2    Carnevale, K.3    Liem, R.K.H.4
  • 27
    • 0028941830 scopus 로고
    • Catecholaminergic innervation of the suprachiasmatic nucleus in the adult rat: Ultrastructural relationships with neurons containing vasoactive intestinal peptide or vasopressin
    • Jacomy, H., and O. Bosler. 1995. Catecholaminergic innervation of the suprachiasmatic nucleus in the adult rat: ultrastructural relationships with neurons containing vasoactive intestinal peptide or vasopressin. Cell Tissue Res. 280: 87-96.
    • (1995) Cell Tissue Res. , vol.280 , pp. 87-96
    • Jacomy, H.1    Bosler, O.2
  • 29
    • 0030747442 scopus 로고    scopus 로고
    • Degenerative ataxias: Genetics, pathogenesis and animal models
    • Kakizuka, A. 1997. Degenerative ataxias: genetics, pathogenesis and animal models. Curr. Opin. Neurol. 10:285-290.
    • (1997) Curr. Opin. Neurol. , vol.10 , pp. 285-290
    • Kakizuka, A.1
  • 30
    • 0029840428 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1: Gene multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes
    • Kato, S., M. Shimoda, Y. Watanabe, K. Nakashima, K. Takahashi, and E. Ohama. 1996. Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1: gene multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes. J. Neuropathol. Exp. Neurol. 55: 1089-1101.
    • (1996) J. Neuropathol. Exp. Neurol. , vol.55 , pp. 1089-1101
    • Kato, S.1    Shimoda, M.2    Watanabe, Y.3    Nakashima, K.4    Takahashi, K.5    Ohama, E.6
  • 32
    • 0032511077 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor (LIF) production in a mouse model of spinal trauma
    • Kurek, J.B., T.M. Bennett, J.J. Bower, C.M. Muldoon, and L. Austin. 1998. Leukaemia inhibitory factor (LIF) production in a mouse model of spinal trauma. Neurosci. Lett. 249:1-4.
    • (1998) Neurosci. Lett. , vol.249 , pp. 1-4
    • Kurek, J.B.1    Bennett, T.M.2    Bower, J.J.3    Muldoon, C.M.4    Austin, L.5
  • 33
    • 0031915931 scopus 로고    scopus 로고
    • Transcriptional activation of the mouse peripherin gene by leukemia inhibitory factor: Involvement of STAT proteins
    • Lecomte, M.J., M. Basseville, F. Landon, V. Karpov, and M. Fauquet. 1998. Transcriptional activation of the mouse peripherin gene by leukemia inhibitory factor: involvement of STAT proteins. J. Neurochem. 70:971-982.
    • (1998) J. Neurochem. , vol.70 , pp. 971-982
    • Lecomte, M.J.1    Basseville, M.2    Landon, F.3    Karpov, V.4    Fauquet, M.5
  • 34
    • 0027293898 scopus 로고
    • Neurofilaments are obligate heteropolymers in vivo
    • Lee, M.K., Z. Xu, P.C. Wong, and D.W. Cleveland. 1993. Neurofilaments are obligate heteropolymers in vivo. J. Cell Biol. 122:1337-1350.
    • (1993) J. Cell Biol. , vol.122 , pp. 1337-1350
    • Lee, M.K.1    Xu, Z.2    Wong, P.C.3    Cleveland, D.W.4
  • 35
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death: Implications for the pathogenesis of human motor neuron disease
    • Lee, M.K., J.R. Marszalek, and D.W. Cleveland. 1994. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron. 13:975-988.
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 36
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
    • Lin, C.L., L.A. Bristol, L. Jin, M. Dykes-Hoberg, T. Crawford, L. Clawson, and J.D. Rothstein. 1998. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron. 20:589-602.
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.L.1    Bristol, L.A.2    Jin, T.3    Dykes-Hoberg, M.4    Crawford, T.5    Clawson, L.6    Rothstein, J.D.7
  • 37
    • 0033583561 scopus 로고    scopus 로고
    • Severe neuronal losses with age in the parietal cortex and ventrobasal thalamus of mice transgenic for the human NF-L neurofilament protein
    • Ma, D., L. Descarries, K.D. Micheva, Y. Lepage, J.-P. Julien, and G. Doucet. 1999. Severe neuronal losses with age in the parietal cortex and ventrobasal thalamus of mice transgenic for the human NF-L neurofilament protein. J. Comp. Neurol. 406:433-448.
    • (1999) J. Comp. Neurol. , vol.406 , pp. 433-448
    • Ma, D.1    Descarries, L.2    Micheva, K.D.3    Lepage, Y.4    Julien, J.-P.5    Doucet, G.6
  • 38
    • 0027478805 scopus 로고
    • Peripherin immunoreactive structures in amyotrophic lateral sclerosis
    • Migheli, A., T. Pezzulo, A. Attanasio, and D. Schiffer. 1993. Peripherin immunoreactive structures in amyotrophic lateral sclerosis. Lab. Investig. 68:185-191.
    • (1993) Lab. Investig. , vol.68 , pp. 185-191
    • Migheli, A.1    Pezzulo, T.2    Attanasio, A.3    Schiffer, D.4
  • 39
    • 0025238746 scopus 로고
    • Alterations in levels of mRNAs coding for neurofilament protein subunits during regeneration
    • Muma, N.A., P.N. Hoffman, H.H. Slunt, M.D. Applegate, I. Lieberburg, and D.L. Price. 1990. Alterations in levels of mRNAs coding for neurofilament protein subunits during regeneration. Exp. Neurol. 107:230-235.
    • (1990) Exp. Neurol. , vol.107 , pp. 230-235
    • Muma, N.A.1    Hoffman, P.N.2    Slunt, H.H.3    Applegate, M.D.4    Lieberburg, I.5    Price, D.L.6
  • 40
    • 0032976739 scopus 로고    scopus 로고
    • Expanded polyglutamine domain proteins hind neurofilament and alter the neurofilament network
    • Nagai, Y., O. Onodera, J. Chun, W.J. Strittmatter, and J.R. Burke. 1999. Expanded polyglutamine domain proteins hind neurofilament and alter the neurofilament network. Exp. Neurol. 155:195-203.
    • (1999) Exp. Neurol. , vol.155 , pp. 195-203
    • Nagai, Y.1    Onodera, O.2    Chun, J.3    Strittmatter, W.J.4    Burke, J.R.5
  • 41
    • 0022345653 scopus 로고
    • Alpha-internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues
    • Pachter, J.S., and R.K. Liem. 1985. alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues. J. Cell Biol. 101:1316-1322.
    • (1985) J. Cell Biol. , vol.101 , pp. 1316-1322
    • Pachter, J.S.1    Liem, R.K.2
  • 42
    • 0026735809 scopus 로고
    • GAP-43 gene expression is increased in anterior horn cells of amyotrophic lateral sclerosis
    • Parhad, I.M., R. Oishi, and A.W. Clark. 1992. GAP-43 gene expression is increased in anterior horn cells of amyotrophic lateral sclerosis. Ann. Neurol. 31:593-597.
    • (1992) Ann. Neurol. , vol.31 , pp. 593-597
    • Parhad, I.M.1    Oishi, R.2    Clark, A.W.3
  • 43
    • 0023860804 scopus 로고
    • Distribution of a novel 57 kDA intermediate filament IF protein in the nervous system
    • Parysek, L.M., and R.D. Goldman. 1988. Distribution of a novel 57 kDA intermediate filament IF protein in the nervous system. J. Neurosci. 8:555-563.
    • (1988) J. Neurosci. , vol.8 , pp. 555-563
    • Parysek, L.M.1    Goldman, R.D.2
  • 44
    • 0025942497 scopus 로고
    • Some neural intermediate filaments contain both peripherin and the neurofilament proteins
    • Parysek, L.M., MA. McReynolds, R.D. Goldman, and C.A. Ley. 1991. Some neural intermediate filaments contain both peripherin and the neurofilament proteins. J. Neurosci. Res. 30:80-91.
    • (1991) J. Neurosci. Res. , vol.30 , pp. 80-91
    • Parysek, L.M.1    McReynolds, M.A.2    Goldman, R.D.3    Ley, C.A.4
  • 45
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps, M.E., G.W. Huntley, P.R. Hof, J.H. Morrison, and J.W. Gordon. 1995. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad, Sci. USA. 92:689-693.
    • (1995) Proc. Natl. Acad, Sci. USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 48
    • 0032485033 scopus 로고    scopus 로고
    • Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: Immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases
    • Sekizawa, T., H. Openshaw, K. Ohbo, K. Sugamura, Y. Itoyama, and J.C. Niland. 1998. Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases. J. Neurol. Sci. 154:194-199.
    • (1998) J. Neurol. Sci. , vol.154 , pp. 194-199
    • Sekizawa, T.1    Openshaw, H.2    Ohbo, K.3    Sugamura, K.4    Itoyama, Y.5    Niland, J.C.6
  • 49
    • 0029927679 scopus 로고    scopus 로고
    • Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
    • Shibata, N., A. Hirano, M. Kobayashi, T. Siddique, H.X. Deng, W.Y. Hung, T. Kato, and K. Asayama. 1996. Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. Neuropathol. Exp. Neurol. 55: 481-490.
    • (1996) Neuropathol. Exp. Neurol. , vol.55 , pp. 481-490
    • Shibata, N.1    Hirano, A.2    Kobayashi, M.3    Siddique, T.4    Deng, H.X.5    Hung, W.Y.6    Kato, T.7    Asayama, K.8
  • 50
    • 0029836184 scopus 로고    scopus 로고
    • Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells
    • Sterneck, E., D.R. Kaplan, and P.F. Johnson. 1996. Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells. J. Neurochem. 67:1365-1374.
    • (1996) J. Neurochem. , vol.67 , pp. 1365-1374
    • Sterneck, E.1    Kaplan, D.R.2    Johnson, P.F.3
  • 51
    • 0025185388 scopus 로고
    • Regulation of peripherin and neurofilament expression in regenerating rat motor neurons
    • Troy, C.M., N.A. Muma, L.A. Greene, D.L. Price, and M.L. Shelanski. 1990a. Regulation of peripherin and neurofilament expression in regenerating rat motor neurons. Brain Res. 529:232-238.
    • (1990) Brain Res. , vol.529 , pp. 232-238
    • Troy, C.M.1    Muma, N.A.2    Greene, L.A.3    Price, D.L.4    Shelanski, M.L.5
  • 52
    • 0025335775 scopus 로고
    • Ontogeny of the neuronal intermediate filament protein, peripherin, in the mouse embryo
    • Troy, C.M., K. Brown, L.A. Greene, and M.L. Shelanski. 1990b. Ontogeny of the neuronal intermediate filament protein, peripherin, in the mouse embryo. Neuroscience. 30:217-237.
    • (1990) Neuroscience , vol.30 , pp. 217-237
    • Troy, C.M.1    Brown, K.2    Greene, L.A.3    Shelanski, M.L.4
  • 53
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu, P.H., P. Raju, K.A. Robinson, M.E. Gurney, J.O. Trojanowski, and V.M. Lee. 1996. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. USA. 93:3155-3160.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3155-3160
    • Tu, P.H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.O.5    Lee, V.M.6
  • 54
    • 0030614372 scopus 로고    scopus 로고
    • Selective degeneration of purkinje cells with lewy body-like inclusions in aged NFHLACZ transgenic mice
    • Tu, P.H., K.A. Robinson, F. de Snoo, J. Eyer, A. Peterson, V.M. Lee, and J.Q. Trojanowski. 1997. Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice. J. Neurosci. 17:1064-1074.
    • (1997) J. Neurosci. , vol.17 , pp. 1064-1074
    • Tu, P.H.1    Robinson, K.A.2    De Snoo, F.3    Eyer, J.4    Peterson, A.5    Lee, V.M.6    Trojanowski, J.Q.7
  • 56
    • 0032482976 scopus 로고    scopus 로고
    • Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant
    • Williamson, T.L., L.I. Bruijn, O. Zhu, K.L. Anderson, S.D. Anderson, J.P. Julien, and D.W. Cleveland. 1998. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc. Natl. Acad. Sci. USA. 95:9631-9636.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9631-9636
    • Williamson, T.L.1    Bruijn, L.I.2    Zhu, O.3    Anderson, K.L.4    Anderson, S.D.5    Julien, J.P.6    Cleveland, D.W.7
  • 57
    • 0033366384 scopus 로고    scopus 로고
    • Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
    • Williamson, T.L., and D.W. Cleveland. 1999. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci. 2:50-56.
    • (1999) Nat. Neurosci. , vol.2 , pp. 50-56
    • Williamson, T.L.1    Cleveland, D.W.2
  • 58
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong, P.C., C.A. Pardo, D.R. Borchelt, M.K. Lee, N.G. Copeland, N.A. Jenkins, S.S. Sisodia, D.W. Cleveland, and D.L. Price. 1995. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 59
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu, Z., L.C. Cork, J.W. Griffin, and D.W. Cleveland. 1993. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell. 73:23-33.
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4
  • 60
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • Zhang, B., P.H. Tu, F. Abtahian, J.Q. Trojanowski, and V.M.Y. Lee. 1997. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J. Cell Biol. 139:1307-1315.
    • (1997) J. Cell Biol. , vol.139 , pp. 1307-1315
    • Zhang, B.1    Tu, P.H.2    Abtahian, F.3    Trojanowski, J.Q.4    Lee, V.M.Y.5
  • 61
    • 0031263931 scopus 로고    scopus 로고
    • Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments
    • Zhu, Q., S. Couillard-Després, and J.P. Julien. 1997. Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Exp. Neurol. 148:299-316.
    • (1997) Exp. Neurol. , vol.148 , pp. 299-316
    • Zhu, Q.1    Couillard-Després, S.2    Julien, J.P.3


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