Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis

Journal of Neuroscience

Volumn 22, Issue 16, 2002, Pages 6920-6928

  Wang, Li Jun ^a   Lu, Yan Yan ^a   Muramatsu, Shin ichi ^a   Ikeguchi, Kunihiko ^a   Fujimoto, Ken ichi ^a   Okada, Takashi ^a   Mizukami, Hiroaki ^a   Matsushita, Takashi ^a   Hanazono, Yutaka ^a   Kume, Akihiro ^a   Nagatsu, Toshiharu ^b   Ozawa, Keiya ^a   Nakano, Imaharu ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

Adeno associated virus vector; Amyotrophic lateral sclerosis; Gene therapy; Glial cell line derived neurotrophic factor; Motoneuron; Retrograde transport

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; GENE DELIVERY SYSTEM; GENE THERAPY; HUMAN; HUMAN CELL; LIFESPAN; MALE; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE INNERVATION; NERVE DEGENERATION; NERVE FIBER; NEUROMUSCULAR SYNAPSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD VENTRAL HORN; TRANSGENIC MOUSE;

EID: 0037104725     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-16-06920.2002     Document Type: Article

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