-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971-983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
4
-
-
0030712094
-
Transgenic mouse models of neurodegenerative disease caused by CAG/polyglutamine expansions
-
Bates G. P. and Davies S. W. (1997) Transgenic mouse models of neurodegenerative disease caused by CAG/polyglutamine expansions. Mol. Med. Today 3: 508-515
-
(1997)
Mol. Med. Today
, vol.3
, pp. 508-515
-
-
Bates, G.P.1
Davies, S.W.2
-
5
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel J. P., Myers R. H., Stevens T. J., Ferrante R. J., Bird E. D. and Richardson E. P. Jr (1985) Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 44: 559-577
-
(1985)
J. Neuropathol. Exp. Neurol.
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson Jr., E.P.6
-
6
-
-
0032052003
-
Huntingtin protein colocalizes with lesions of neurodegenerative diseases: An investigation in Huntington's, Alzheimer's and Pick's diseases
-
Singhrao S. K., Thomas P., Wood J. D., MacMillan J. C., Neal J. W., Harper P. S. et al. (1998) Huntingtin protein colocalizes with lesions of neurodegenerative diseases: an investigation in Huntington's, Alzheimer's and Pick's diseases. Exp. Neurol. 150: 213-222
-
(1998)
Exp. Neurol.
, vol.150
, pp. 213-222
-
-
Singhrao, S.K.1
Thomas, P.2
Wood, J.D.3
MacMillan, J.C.4
Neal, J.W.5
Harper, P.S.6
-
7
-
-
0033007867
-
Expression of the Huntington's disease gene is regulated in astrocytes in the arcuate nucleus of the hypothalamus of postpartum rats
-
Hebb M. O., Denovan-Wright E. M. and Robertson H. A. (1999) Expression of the Huntington's disease gene is regulated in astrocytes in the arcuate nucleus of the hypothalamus of postpartum rats. FASEB J. 13: 1099-1106
-
(1999)
FASEB J.
, vol.13
, pp. 1099-1106
-
-
Hebb, M.O.1
Denovan-Wright, E.M.2
Robertson, H.A.3
-
8
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
Luthi-Carter R., Hanson S. A., Strand A. D., Bergstrom D. A., Chun W., Peters N. L. et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum. Mol. Genet. 11: 1911-1926
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
-
9
-
-
0141866674
-
Inclusion formation in Huntington's disease R6/2 mouse muscle cultures
-
Orth M., Cooper J. M., Bates G. P. and Schapira A. H. (2003) Inclusion formation in Huntington's disease R6/2 mouse muscle cultures. J. Neurochem. 87: 1-6
-
(2003)
J. Neurochem.
, vol.87
, pp. 1-6
-
-
Orth, M.1
Cooper, J.M.2
Bates, G.P.3
Schapira, A.H.4
-
10
-
-
0033757718
-
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
-
Dragatsis I., Levine M. S. and Zeitlin S. (2000) Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat. Genet. 26: 300-306
-
(2000)
Nat. Genet.
, vol.26
, pp. 300-306
-
-
Dragatsis, I.1
Levine, M.S.2
Zeitlin, S.3
-
11
-
-
0037002444
-
Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression
-
Andreassen O. A., Dedeoglu A., Stanojevic V., Hughes D. B., Browne S. E., Leech C. A. et al. (2002) Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression. Neurobiol. Dis. 11: 410-424
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 410-424
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Stanojevic, V.3
Hughes, D.B.4
Browne, S.E.5
Leech, C.A.6
-
12
-
-
20044392282
-
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis
-
in press
-
Bjorkqvist M., Fex M., Renstrom E., Wierup N., Petersen A., Gil J. et al. (2005) The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis. Hum. Mol. Genet., in press
-
(2005)
Hum. Mol. Genet.
-
-
Bjorkqvist, M.1
Fex, M.2
Renstrom, E.3
Wierup, N.4
Petersen, A.5
Gil, J.6
-
13
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
DiFiglia M., Sapp E., Chase K., Schwarz C., Meloni A., Young C. et al. (1995) Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14: 1075-1081
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
-
14
-
-
0031867231
-
Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways
-
Velier J., Kim M., Schwarz C., Kim T. W., Sapp E., Chase K. et al. (1998) Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways. Exp. Neurol. 152: 34-40
-
(1998)
Exp. Neurol.
, vol.152
, pp. 34-40
-
-
Velier, J.1
Kim, M.2
Schwarz, C.3
Kim, T.W.4
Sapp, E.5
Chase, K.6
-
15
-
-
0032190391
-
The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): Comparison with huntingtin in rat and human
-
Gutekunst C. A., Li S. H., Yi H., Ferrante R. J., Li X. J. and Hersch S. M. (1998) The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. J. Neurosci. 18: 7674-7686
-
(1998)
J. Neurosci.
, vol.18
, pp. 7674-7686
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Ferrante, R.J.4
Li, X.J.5
Hersch, S.M.6
-
16
-
-
0034703860
-
Huntingtin: An iron-regulated protein essential for normal nuclear and perinuclear organelles
-
Hilditch-Maguire P., Trettel F., Passani L. A., Auerbach A., Persichetti F. and MacDonald M. E. (2000) Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles. Hum. Mol. Genet. 9: 2789-2797
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2789-2797
-
-
Hilditch-Maguire, P.1
Trettel, F.2
Passani, L.A.3
Auerbach, A.4
Persichetti, F.5
MacDonald, M.E.6
-
17
-
-
0029055717
-
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
-
Nasir J., Floresco S. B., O'Kusky J. R., Diewert V. M., Richman J. M., Zeisler J. et al. (1995) Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81: 811-823
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
Floresco, S.B.2
O'Kusky, J.R.3
Diewert, V.M.4
Richman, J.M.5
Zeisler, J.6
-
18
-
-
0034657112
-
Wild-type huntingtin protects from apoptosis upstream of caspase-3
-
Rigamonti D., Bauer J. H., De-Fraja C., Conti L., Sipione S., Sciorati C. et al. (2000) Wild-type huntingtin protects from apoptosis upstream of caspase-3. J. Neurosci. 20: 3705-3713
-
(2000)
J. Neurosci.
, vol.20
, pp. 3705-3713
-
-
Rigamonti, D.1
Bauer, J.H.2
De-Fraja, C.3
Conti, L.4
Sipione, S.5
Sciorati, C.6
-
19
-
-
0037131263
-
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons
-
Goffredo D., Rigamonti D., Tartari M., De Micheli A., Verderio C., Matteoli M. et al. (2002) Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons. J. Biol. Chem. 277: 39594-39598
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39594-39598
-
-
Goffredo, D.1
Rigamonti, D.2
Tartari, M.3
De Micheli, A.4
Verderio, C.5
Matteoli, M.6
-
20
-
-
1242338856
-
Huntingtin-protein interactions and the pathogenesis of Huntington's disease
-
Li S. H. and Li X. J. (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet. 20: 146-154
-
(2004)
Trends Genet.
, vol.20
, pp. 146-154
-
-
Li, S.H.1
Li, X.J.2
-
21
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150(Glued) subunit of dynactin
-
Engelender S., Sharp A. H., Colomer V., Tokito M. K., Lanahan A., Worley P. et al. (1997) Huntingtin-associated protein 1 (HAP1) interacts with the p150(Glued) subunit of dynactin. Hum. Mol. Genet. 6: 2205-2212
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
-
23
-
-
4444316194
-
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro
-
Trushina E., Dyer R. B., Badger J. D. 2nd, Ure D., Eide L., Tran D. D. et al. (2004) Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol. Cell. Biol. 24: 8195-8209
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8195-8209
-
-
Trushina, E.1
Dyer, R.B.2
Badger II, J.D.3
Ure, D.4
Eide, L.5
Tran, D.D.6
-
24
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier L. R., Charrin B. C., Borrell-Pages M., Dompierre J. P., Rangone H., Cordelieres F. P. et al. (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118: 127-138
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
-
25
-
-
0029152808
-
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
-
Gutekunst C. A., Levey A. I., Heilman C. J., Whaley W. L., Yi H., Nash N. R. et al. (1995) Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc. Natl. Acad. Sci. USA 92: 8710-8714
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8710-8714
-
-
Gutekunst, C.A.1
Levey, A.I.2
Heilman, C.J.3
Whaley, W.L.4
Yi, H.5
Nash, N.R.6
-
26
-
-
0036500862
-
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: Relevance to Huntington's disease
-
Hoffner G., Kahlem P. and Djian P. (2002) Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease. J. Cell Sci. 115: 941-948
-
(2002)
J. Cell Sci.
, vol.115
, pp. 941-948
-
-
Hoffner, G.1
Kahlem, P.2
Djian, P.3
-
27
-
-
10744224530
-
Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport
-
Szebenyi G., Morfini G. A., Babcock A., Gould M., Selkoe K., Stenoien D. L. et al. (2003) Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport. Neuron 40: 41-52
-
(2003)
Neuron
, vol.40
, pp. 41-52
-
-
Szebenyi, G.1
Morfini, G.A.2
Babcock, A.3
Gould, M.4
Selkoe, K.5
Stenoien, D.L.6
-
28
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena S., Her L. S., Brusch R. G., Laymon R. A., Niesman I. R., Gordesky-Gold B. et al. (2003) Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 40: 25-40
-
(2003)
Neuron
, vol.40
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
-
29
-
-
0141987860
-
The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg
-
Ciechanover A. and Brundin P. (2003) The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 40: 427-446
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
30
-
-
0032924105
-
Chaperone-mediated protein folding
-
Fink A. L. (1999) Chaperone-mediated protein folding. Physiol. Rev. 79: 425-449
-
(1999)
Physiol. Rev.
, vol.79
, pp. 425-449
-
-
Fink, A.L.1
-
31
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl F. U. and Hayer-Hartl M. (2002) Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295: 1852-1858
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
32
-
-
0036671821
-
Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions
-
Lunkes A., Lindenberg K. S., Ben-Haiem L., Weber C., Devys D., Landwehrmeyer G. B. et al. (2002) Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions. Mol. Cell. 10: 259-269
-
(2002)
Mol. Cell.
, vol.10
, pp. 259-269
-
-
Lunkes, A.1
Lindenberg, K.S.2
Ben-Haiem, L.3
Weber, C.4
Devys, D.5
Landwehrmeyer, G.B.6
-
33
-
-
0042921188
-
Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release
-
Li H., Wyman T., Yu Z. X., Li S. H. and Li X. J. (2003) Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release. Hum. Mol. Genet. 12: 2021-2030
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2021-2030
-
-
Li, H.1
Wyman, T.2
Yu, Z.X.3
Li, S.H.4
Li, X.J.5
-
34
-
-
0842322740
-
Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction
-
Qin Z. H., Wang Y., Sapp E., Cuiffo B., Wanker E., Hayden M. R. et al. (2004) Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction. J. Neurosci. 24: 269-281
-
(2004)
J. Neurosci.
, vol.24
, pp. 269-281
-
-
Qin, Z.H.1
Wang, Y.2
Sapp, E.3
Cuiffo, B.4
Wanker, E.5
Hayden, M.R.6
-
35
-
-
0034754875
-
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation
-
Waelter S., Boeddrich A., Lurz R., Scherzinger E., Lueder G., Lehrach H. et al. (2001) Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol. Biol. Cell 12: 1393-1407
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1393-1407
-
-
Waelter, S.1
Boeddrich, A.2
Lurz, R.3
Scherzinger, E.4
Lueder, G.5
Lehrach, H.6
-
36
-
-
3342879140
-
Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates
-
Doi H., Mitsui K., Kurosawa M., Machida Y., Kuroiwa Y. and Nukina N. (2004) Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates. FEBS Lett. 571: 171-176
-
(2004)
FEBS Lett.
, vol.571
, pp. 171-176
-
-
Doi, H.1
Mitsui, K.2
Kurosawa, M.3
Machida, Y.4
Kuroiwa, Y.5
Nukina, N.6
-
37
-
-
0042808497
-
Ubiquitin-inediated sequestration of normal cellular proteins into polyglutamine aggregates
-
Donaldson K. M., Li W., Ching K. A., Batalov S., Tsai C. C. and Joazeiro C. A. (2003) Ubiquitin-inediated sequestration of normal cellular proteins into polyglutamine aggregates. Proc. Natl. Acad. Sci. USA 100: 8892-8897
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8892-8897
-
-
Donaldson, K.M.1
Li, W.2
Ching, K.A.3
Batalov, S.4
Tsai, C.C.5
Joazeiro, C.A.6
-
38
-
-
0037059042
-
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
-
Sakahira H., Breuer P., Hayer-Hartl M. K. and Hartl F. U. (2002) Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proc. Natl. Acad. Sci. USA 99 (suppl. 4): 16412-16418
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.4 SUPPL.
, pp. 16412-16418
-
-
Sakahira, H.1
Breuer, P.2
Hayer-Hartl, M.K.3
Hartl, F.U.4
-
39
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
Steffan J. S., Kazantsev A., Spasic-Boskovic O., Greenwald M., Zhu Y. Z., Gohler H. et al. (2000) The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc. Natl. Acad. Sci. USA 97: 6763-6768
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
-
40
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora F. C. Jr, Sasaki M., Peters M. F., Huang H., Cooper J. K., Yamada M. et al. (2001) Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 291: 2423-2428.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
-
41
-
-
1042289730
-
Decreased cAMP response element-mediated transcription: An early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis
-
Sugars K. L., Brown R., Cook L. J., Swartz J. and Rubinsztein D. C. (2004) Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis. J. Biol. Chem. 279: 4988-4999
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4988-4999
-
-
Sugars, K.L.1
Brown, R.2
Cook, L.J.3
Swartz, J.4
Rubinsztein, D.C.5
-
42
-
-
0035880474
-
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease
-
Wyttenbach A., Swartz J., Kita H., Thykjaer T., Carmichael J., Bradley J. et al. (2001) Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum. Mol. Genet. 10: 1829-1845
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1829-1845
-
-
Wyttenbach, A.1
Swartz, J.2
Kita, H.3
Thykjaer, T.4
Carmichael, J.5
Bradley, J.6
-
43
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato C., Tartari M., Crotti A., Goffredo D., Valenza M., Conti L. et al. (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 35: 76-83
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
-
44
-
-
0036173896
-
Interaction of Huntington disease protein with transcriptional activator sp1
-
Li S. H., Cheng A. L., Zhou H., Lam S., Rao M., Li H. et al. (2002) Interaction of Huntington disease protein with transcriptional activator sp1. Mol. Cell. Biol. 22: 1277-1287
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1277-1287
-
-
Li, S.H.1
Cheng, A.L.2
Zhou, H.3
Lam, S.4
Rao, M.5
Li, H.6
-
45
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
Dunah A. W., Jeong H., Griffin A., Kim Y. M., Standaert D. G., Hersch S. M. et al. (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 296: 2238-2243
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
-
46
-
-
0037408279
-
Transcriptional abnormalities in Huntington disease
-
Sugars K. L. and Rubinsztein D. C. (2003) Transcriptional abnormalities in Huntington disease. Trends Genet. 19: 233-238
-
(2003)
Trends Genet.
, vol.19
, pp. 233-238
-
-
Sugars, K.L.1
Rubinsztein, D.C.2
-
47
-
-
8844220536
-
Huntingtin and the molecular pathogenesis of Huntington's disease
-
Landles C. and Bates G. P. (2004) Huntingtin and the molecular pathogenesis of Huntington's disease. EMBO Rep. 5: 958-963
-
(2004)
EMBO Rep.
, vol.5
, pp. 958-963
-
-
Landles, C.1
Bates, G.P.2
-
48
-
-
0742287915
-
CRE-mediated transcription is increased in Huntington's disease transgenic mice
-
Obrietan K. and Hoyt K. R. (2004) CRE-mediated transcription is increased in Huntington's disease transgenic mice. J. Neurosci. 24: 791-796
-
(2004)
J. Neurosci.
, vol.24
, pp. 791-796
-
-
Obrietan, K.1
Hoyt, K.R.2
-
49
-
-
0037090927
-
Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice
-
Yu Z. X., Li S. H., Nguyen H. P. and Li X. J. (2002) Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice. Hum. Mol. Genet. 11: 905-914
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 905-914
-
-
Yu, Z.X.1
Li, S.H.2
Nguyen, H.P.3
Li, X.J.4
-
50
-
-
0037101837
-
Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
-
Luthi-Carter R., Strand A. D., Hanson S. A., Kooperberg C., Schilling G., La Spada A. R. et al. (2002) Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum. Mol. Genet. 11: 1927-1937
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1927-1937
-
-
Luthi-Carter, R.1
Strand, A.D.2
Hanson, S.A.3
Kooperberg, C.4
Schilling, G.5
La Spada, A.R.6
-
51
-
-
0037101838
-
Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease
-
Chan E. Y., Luthi-Carter R., Strand A., Solano S. M., Hanson S. A., DeJohn M. M. et al. (2002) Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Hum. Mol. Genet. 11: 1939-1951
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1939-1951
-
-
Chan, E.Y.1
Luthi-Carter, R.2
Strand, A.3
Solano, S.M.4
Hanson, S.A.5
DeJohn, M.M.6
-
52
-
-
0037101839
-
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
-
Sipione S., Rigamonti D., Valenza M., Zuccato C., Conti L., Pritchard J. et al. (2002) Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum. Mol. Genet. 11: 1953-1965
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1953-1965
-
-
Sipione, S.1
Rigamonti, D.2
Valenza, M.3
Zuccato, C.4
Conti, L.5
Pritchard, J.6
-
53
-
-
0029796093
-
Identification of potential target genes for the neuron restrictive silencer factor
-
Schoenherr C. J., Paquette A. J. and Anderson D. J. (1996) Identification of potential target genes for the neuron restrictive silencer factor. Proc. Natl. Acad. Sci. USA 93: 9881-9886
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9881-9886
-
-
Schoenherr, C.J.1
Paquette, A.J.2
Anderson, D.J.3
-
56
-
-
0035030442
-
Molecular mechanisms of neurotransmitter release
-
Fon E. A. and Edwards R. H. (2001) Molecular mechanisms of neurotransmitter release. Muscle Nerve 24: 581-601
-
(2001)
Muscle Nerve
, vol.24
, pp. 581-601
-
-
Fon, E.A.1
Edwards, R.H.2
-
57
-
-
2342544141
-
Cellular and molecular mechanisms of presynaptic assembly
-
Ziv N. E. and Garner C. C. (2004) Cellular and molecular mechanisms of presynaptic assembly. Nat. Rev. Neurosci. 5: 385-399
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 385-399
-
-
Ziv, N.E.1
Garner, C.C.2
-
58
-
-
0034646426
-
Effects of heat shock, heat shock protein 40 (HDJ-2) and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
-
Wyttenbach A., Carmichael J., Swartz J., Furlong R. A., Narain Y., Rankin J. et al. (2000) Effects of heat shock, heat shock protein 40 (HDJ-2) and proteasome inhibition on protein aggregation in cellular models of Huntington's disease. Proc. Natl. Acad. Sci. USA 97: 2898-2903
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2898-2903
-
-
Wyttenbach, A.1
Carmichael, J.2
Swartz, J.3
Furlong, R.A.4
Narain, Y.5
Rankin, J.6
-
59
-
-
0036382909
-
Abnormal phosphorylation of synapsin I predicts a neuronal transmission impairment in the R6/2 Huntington's disease transgenic mice
-
Lievens J. C., Woodman B., Mahal A. and Bates G. P. (2002) Abnormal phosphorylation of synapsin I predicts a neuronal transmission impairment in the R6/2 Huntington's disease transgenic mice. Mol. Cell. Neurosci. 20: 638-648
-
(2002)
Mol. Cell. Neurosci.
, vol.20
, pp. 638-648
-
-
Lievens, J.C.1
Woodman, B.2
Mahal, A.3
Bates, G.P.4
-
60
-
-
0036673069
-
Snares and Munc18 in synaptic vesicle fusion
-
Rizo J. and Sudhof T. C. (2002) Snares and Munc18 in synaptic vesicle fusion. Nat. Rev. Neurosci. 3: 64-653
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 64-653
-
-
Rizo, J.1
Sudhof, T.C.2
-
61
-
-
0035158533
-
Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease
-
Morton A. J. and Edwardson J. M. (2001) Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease. J. Neurochem. 76: 166-172
-
(2001)
J. Neurochem.
, vol.76
, pp. 166-172
-
-
Morton, A.J.1
Edwardson, J.M.2
-
62
-
-
0035883175
-
Abnormalities in the synaptic vesicle fusion machinery in Huntington's disease
-
Morton A. J., Faull R. L. and Edwardson J. M. (2001) Abnormalities in the synaptic vesicle fusion machinery in Huntington's disease. Brain Res. Bull. 56: 111-117
-
(2001)
Brain Res. Bull.
, vol.56
, pp. 111-117
-
-
Morton, A.J.1
Faull, R.L.2
Edwardson, J.M.3
-
63
-
-
0041731977
-
Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II
-
Edwardson J. M., Wang C. T., Gong B., Wyttenbach A., Bai J., Jackson M. B. et al. (2003) Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II. J. Biol. Chem. 278: 30849-30853
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30849-30853
-
-
Edwardson, J.M.1
Wang, C.T.2
Gong, B.3
Wyttenbach, A.4
Bai, J.5
Jackson, M.B.6
-
64
-
-
0141618325
-
Complexin II is essential for normal neurological function in mice
-
Glynn D., Bortnick R. A. and Morton A. J. (2003) Complexin II is essential for normal neurological function in mice. Hum. Mol. Genet. 12: 2431-2448
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2431-2448
-
-
Glynn, D.1
Bortnick, R.A.2
Morton, A.J.3
-
65
-
-
24344444735
-
Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction
-
in press
-
Smith R., Petersen A., Bates G., Brundin P. and Li J. Y. (2005) Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction. Neurobiol. Dis., in press
-
(2005)
Neurobiol. Dis.
-
-
Smith, R.1
Petersen, A.2
Bates, G.3
Brundin, P.4
Li, J.Y.5
-
66
-
-
0029077932
-
Evidence that the Rab3a-binding protein, rabphilin3a, enhances regulated secretion. Studies in adrenal chromaffin cells
-
Chung S. H., Takai Y. and Holz R. W. (1995) Evidence that the Rab3a-binding protein, rabphilin3a, enhances regulated secretion. Studies in adrenal chromaffin cells. J. Biol. Chem. 270: 16714-16718
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16714-16718
-
-
Chung, S.H.1
Takai, Y.2
Holz, R.W.3
-
67
-
-
0027402975
-
Synaptic vesicle phosphoproteins and regulation of synaptic function
-
Greengard P., Valtorta F., Czernik A. J. and Benfenati F. (1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259: 780-785
-
(1993)
Science
, vol.259
, pp. 780-785
-
-
Greengard, P.1
Valtorta, F.2
Czernik, A.J.3
Benfenati, F.4
-
68
-
-
0022630780
-
Synapsin I is a microtubule-bundling protein
-
Baines A. J. and Bennett V. (1986) Synapsin I is a microtubule-bundling protein. Nature 319: 145-147
-
(1986)
Nature
, vol.319
, pp. 145-147
-
-
Baines, A.J.1
Bennett, V.2
-
69
-
-
0035783462
-
Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene
-
Hansson O., Guatteo E., Mercuri N. B., Bernardi G., Li X. J., Castilho R. F. et al. (2001) Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene. Eur. J. Neurosci. 14: 1492-1504
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 1492-1504
-
-
Hansson, O.1
Guatteo, E.2
Mercuri, N.B.3
Bernardi, G.4
Li, X.J.5
Castilho, R.F.6
-
70
-
-
0346101741
-
Cysteine string protein (CSP) inhibition of N-type calcium channels is blocked by mutant huntingtin
-
Miller L. C., Swayne L. A., Chen L., Feng Z. P., Wacker J. L., Muchowski P. J. et al. (2003) Cysteine string protein (CSP) inhibition of N-type calcium channels is blocked by mutant huntingtin. J. Biol. Chem. 278: 53072-53081
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 53072-53081
-
-
Miller, L.C.1
Swayne, L.A.2
Chen, L.3
Feng, Z.P.4
Wacker, J.L.5
Muchowski, P.J.6
-
71
-
-
0041963057
-
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
-
Tang T. S., Tu H., Chan E. Y., Maximov A., Wang Z., Wellington C. L. et al. (2003) Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron 39: 227-239
-
(2003)
Neuron
, vol.39
, pp. 227-239
-
-
Tang, T.S.1
Tu, H.2
Chan, E.Y.3
Maximov, A.4
Wang, Z.5
Wellington, C.L.6
-
72
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene
-
Cha J. H., Kosinski C. M., Kerner J. A., Alsdorf S. A., Mangiarini L., Davies S. W. et al. (1998) Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene. Proc. Natl. Acad. Sci. USA 95: 6480-6485
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
-
73
-
-
0036850524
-
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis
-
Singaraja R. R., Hadano S., Metzler M., Givan S., Wellington C. L., Warby S. et al. (2002) HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis. Hum. Mol. Genet. 11: 2815-2828
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2815-2828
-
-
Singaraja, R.R.1
Hadano, S.2
Metzler, M.3
Givan, S.4
Wellington, C.L.5
Warby, S.6
-
74
-
-
0036796261
-
PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains
-
Modregger J., DiProspero N. A., Charles V., Tagle D. A. and Plomann M. (2002) PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains. Hum. Mol. Genet. 11: 2547-2558
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2547-2558
-
-
Modregger, J.1
DiProspero, N.A.2
Charles, V.3
Tagle, D.A.4
Plomann, M.5
-
75
-
-
0030986659
-
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
-
Kalchman M. A., Koide H. B., McCutcheon K., Graham R. K., Nichol K., Nishiyama K. et al. (1997) HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain. Nat. Genet.16: 44-53
-
(1997)
Nat. Genet.
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
Koide, H.B.2
McCutcheon, K.3
Graham, R.K.4
Nichol, K.5
Nishiyama, K.6
-
76
-
-
0032186107
-
SH3GL3 associates with the huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates
-
Sittler A., Walter S., Wedemeyer N., Hasenbank R., Scherzinger E., Eickhoff H. et al. (1998) SH3GL3 associates with the huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates. Mol. Cell. 2: 427-436
-
(1998)
Mol. Cell
, vol.2
, pp. 427-436
-
-
Sittler, A.1
Walter, S.2
Wedemeyer, N.3
Hasenbank, R.4
Scherzinger, E.5
Eickhoff, H.6
-
77
-
-
0031056478
-
HIP-I: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
Wanker E. E., Rovira C., Scherzinger E., Hasenbank R., Walter S., Tait D. et al. (1997) HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system. Hum. Mol. Genet. 6: 487-495
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.E.1
Rovira, C.2
Scherzinger, E.3
Hasenbank, R.4
Walter, S.5
Tait, D.6
-
78
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li X. J., Li S. H., Sharp A. H., Nucifora F. C. Jr, Schilling G., Lanahan A. et al. (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378: 398-402
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.J.1
Li, S.H.2
Sharp, A.H.3
Nucifora Jr., F.C.4
Schilling, G.5
Lanahan, A.6
-
79
-
-
0026345013
-
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein
-
Gill S. R., Schroer T. A., Szilak I., Steuer E. R., Sheetz M. P. and Cleveland D. W. (1991) Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J. Cell Biol. 115: 1639-1650
-
(1991)
J. Cell Biol.
, vol.115
, pp. 1639-1650
-
-
Gill, S.R.1
Schroer, T.A.2
Szilak, I.3
Steuer, E.R.4
Sheetz, M.P.5
Cleveland, D.W.6
-
80
-
-
0037008677
-
Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking
-
Li Y., Chin L. S., Levey A. I. and Li L. (2002) Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking. J. Biol. Chem. 277: 28212-28221
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28212-28221
-
-
Li, Y.1
Chin, L.S.2
Levey, A.I.3
Li, L.4
-
81
-
-
0033611051
-
An actin-binding protein of the Sla2/huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles
-
Engqvist-Goldstein A. E., Kessels M. M., Chopra V. S., Hayden M. R. and Drubin D. G. (1999) An actin-binding protein of the Sla2/huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles. J. Cell Biol. 147: 1503-1518
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1503-1518
-
-
Engqvist-Goldstein, A.E.1
Kessels, M.M.2
Chopra, V.S.3
Hayden, M.R.4
Drubin, D.G.5
-
82
-
-
0037205440
-
HIP1 and HIP12 display differential binding to F-actin, AP2 and clathrin. Identification of a novel interaction with clathrin light chain
-
Legendre-Guillemin V., Metzler M., Charbonneau M., Gan L., Chopra V., Philie J. et al. (2002) HIP1 and HIP12 display differential binding to F-actin, AP2 and clathrin. Identification of a novel interaction with clathrin light chain. J. Biol. Chem. 277: 19897-19904
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19897-19904
-
-
Legendre-Guillemin, V.1
Metzler, M.2
Charbonneau, M.3
Gan, L.4
Chopra, V.5
Philie, J.6
-
83
-
-
0037423214
-
Characterization of endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1
-
Modregger J., Schmidt A. A., Ritter B., Huttner W. B. and Plomann M. (2003) Characterization of endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. J. Biol. Chem. 278: 4160-4167
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4160-4167
-
-
Modregger, J.1
Schmidt, A.A.2
Ritter, B.3
Huttner, W.B.4
Plomann, M.5
-
84
-
-
0035180327
-
Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice
-
Nicniocaill B., Haraldsson B., Hansson O., O'Connor W. T. and Brundin P. (2001) Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice. Eur. J. Neurosci. 13: 206-210
-
(2001)
Eur. J. Neurosci.
, vol.13
, pp. 206-210
-
-
Nicniocaill, B.1
Haraldsson, B.2
Hansson, O.3
O'Connor, W.T.4
Brundin, P.5
-
85
-
-
0036345741
-
Impaired glutamate transport and glutamate-glutamine cycling: Downstream effects of the Huntington mutation
-
Behrens P. F., Franz P., Woodman B., Lindenberg K. S. and Landwehrmeyer G. B. (2002) Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain 125: 1908-1922
-
(2002)
Brain
, vol.125
, pp. 1908-1922
-
-
Behrens, P.F.1
Franz, P.2
Woodman, B.3
Lindenberg, K.S.4
Landwehrmeyer, G.B.5
-
86
-
-
0031930027
-
Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia
-
Testa C. M., Friberg I. K., Weiss S. W. and Standaert D. G. (1998) Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia. J. Comp. Neurol. 390: 5-19
-
(1998)
J. Comp. Neurol.
, vol.390
, pp. 5-19
-
-
Testa, C.M.1
Friberg, I.K.2
Weiss, S.W.3
Standaert, D.G.4
-
87
-
-
0033844601
-
Regulation of neurotransmitter release by metabotropic glutamate receptors
-
Cartmell J. and Schoepp D. D. (2000) Regulation of neurotransmitter release by metabotropic glutamate receptors. J. Neurochem. 75: 889-907
-
(2000)
J. Neurochem.
, vol.75
, pp. 889-907
-
-
Cartmell, J.1
Schoepp, D.D.2
-
88
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
Levine M. S., Klapstein G. J., Koppel A., Gruen E., Cepeda C., Vargas M. E. et al. (1999) Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J. Neurosci. Res. 58: 515-532
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
-
89
-
-
0033136692
-
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity and selective striatal neurodegeneration
-
Hodgson J. G., Agopyan N., Gutekunst C. A., Leavitt B. R., LePiane F., Singaraja R. et al. (1999) A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity and selective striatal neurodegeneration. Neuron 23: 181-192
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.A.3
Leavitt, B.R.4
LePiane, F.5
Singaraja, R.6
-
90
-
-
0035816627
-
Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95
-
Sun Y., Savanenin A., Reddy P. H. and Liu Y. F. (2001) Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95. J. Biol. Chem. 276: 24713-24718
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24713-24718
-
-
Sun, Y.1
Savanenin, A.2
Reddy, P.H.3
Liu, Y.F.4
-
91
-
-
10744223572
-
Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: Analysis of mRNA and protein expression, plasma membrane association, interacting proteins and phosphorylation
-
Luthi-Carter R., Apostol B. L., Dunah A. W., DeJohn M. M., Farrell L. A., Bates G. P. et al. (2003) Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins and phosphorylation. Neurobiol. Dis. 14: 624-636
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 624-636
-
-
Luthi-Carter, R.1
Apostol, B.L.2
Dunah, A.W.3
DeJohn, M.M.4
Farrell, L.A.5
Bates, G.P.6
-
92
-
-
0030708576
-
Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease - An in situ hybridization study
-
Arzberger T., Krampfl K., Leimgruber S. and Weindl A. (1997) Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease - an in situ hybridization study. J. Neuropathol. Exp. Neurol. 56: 440-454
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 440-454
-
-
Arzberger, T.1
Krampfl, K.2
Leimgruber, S.3
Weindl, A.4
-
93
-
-
0031013896
-
Competitive binding of alpha-actinin and calmodulin to the NMDA receptor
-
Wyszynski M., Lin J., Rao A., Nigh E., Beggs A. H., Craig A. M. et al. (1997) Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature 385: 439-442
-
(1997)
Nature
, vol.385
, pp. 439-442
-
-
Wyszynski, M.1
Lin, J.2
Rao, A.3
Nigh, E.4
Beggs, A.H.5
Craig, A.M.6
-
94
-
-
0029731554
-
Physical and functional interaction of rabphilin-3A with alpha-actinin
-
Kato M., Sasaki T., Ohya T., Nakanishi H., Nishioka H., Imamura M. et al. (1996) Physical and functional interaction of rabphilin-3A with alpha-actinin. J. Biol. Chem. 271: 31775-31778
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31775-31778
-
-
Kato, M.1
Sasaki, T.2
Ohya, T.3
Nakanishi, H.4
Nishioka, H.5
Imamura, M.6
-
95
-
-
14844314896
-
Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor mediated synaptic currents in a mouse model of Huntington disease
-
Li L., Murphy T. H., Hayden M. R. and Raymond L. A. (2004) Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor mediated synaptic currents in a mouse model of Huntington disease. J. Neurophysiol. 92: 2738-2746
-
(2004)
J. Neurophysiol.
, vol.92
, pp. 2738-2746
-
-
Li, L.1
Murphy, T.H.2
Hayden, M.R.3
Raymond, L.A.4
-
96
-
-
1542346231
-
Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model
-
Jarabek B. R., Yasuda R. P. and Wolfe B. B. (2004) Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model. Brain 127: 505-516
-
(2004)
Brain
, vol.127
, pp. 505-516
-
-
Jarabek, B.R.1
Yasuda, R.P.2
Wolfe, B.B.3
-
97
-
-
0033587760
-
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
-
Hansson O., Petersén Å., Leist M., Nicotera P., Castilho R. F. and Brundin P. (1999) Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity. Proc. Natl. Acad. Sci. USA 96: 8727-8732
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8727-8732
-
-
Hansson, O.1
Petersén, Å.2
Leist, M.3
Nicotera, P.4
Castilho, R.F.5
Brundin, P.6
-
98
-
-
0034889544
-
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length
-
Hansson O., Castilho R. F., Korhonen L., Lindholm D., Bates G. P. and Brundin P. (2001) Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. J. Neurochem. 78: 694-703
-
(2001)
J. Neurochem.
, vol.78
, pp. 694-703
-
-
Hansson, O.1
Castilho, R.F.2
Korhonen, L.3
Lindholm, D.4
Bates, G.P.5
Brundin, P.6
-
99
-
-
0036469255
-
Immediate-early gene response to methamphetamine, haloperidol and quinolinic acid is not impaired in Huntington's disease transgenic mice
-
MacGibbon G. A., Hamilton L. C., Crocker S. F., Costain W. J., Murphy K. M., Robertson H. A. et al. (2002) Immediate-early gene response to methamphetamine, haloperidol and quinolinic acid is not impaired in Huntington's disease transgenic mice. J. Neurosci. Res. 67: 372-378
-
(2002)
J. Neurosci. Res.
, vol.67
, pp. 372-378
-
-
MacGibbon, G.A.1
Hamilton, L.C.2
Crocker, S.F.3
Costain, W.J.4
Murphy, K.M.5
Robertson, H.A.6
-
100
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron M. M., Hansson O., Chen N., Wellington C. L., Leavitt B. R., Brundin P. et al. (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 33: 849-860
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
-
101
-
-
0036254430
-
Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease
-
Petersen A., Chase K., Puschban Z., DiFiglia M., Brundin P. and Aronin N. (2002) Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease. Exp. Neurol. 175: 297-300
-
(2002)
Exp. Neurol.
, vol.175
, pp. 297-300
-
-
Petersen, A.1
Chase, K.2
Puschban, Z.3
DiFiglia, M.4
Brundin, P.5
Aronin, N.6
-
102
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L., Sathasivam K., Seller M., Cozens B., Harper A., Hetherington C. et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87: 493-506
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
-
103
-
-
0036453663
-
Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice
-
Petersen A., Puschban Z., Lotharius J., NicNiocaill B., Wiekop P., O'Connor W. T. et al. (2002) Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice. Neurobiol. Dis. 11: 134-146
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 134-146
-
-
Petersen, A.1
Puschban, Z.2
Lotharius, J.3
NicNiocaill, B.4
Wiekop, P.5
O'Connor, W.T.6
-
104
-
-
0034722642
-
N-Acetylaspartate and DARPP-32 levels decrease in the corpus striatum of Huntington's disease mice
-
van Dellen A., Welch J., Dixon R. M., Cordery P., York D., Styles P. et al. (2000) N-Acetylaspartate and DARPP-32 levels decrease in the corpus striatum of Huntington's disease mice. Neuroreport 11: 3751-3757
-
(2000)
Neuroreport
, vol.11
, pp. 3751-3757
-
-
Van Dellen, A.1
Welch, J.2
Dixon, R.M.3
Cordery, P.4
York, D.5
Styles, P.6
-
105
-
-
0034612255
-
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
-
Bibb J. A., Yan Z., Svenningsson P., Snyder G. L., Pieribone V. A., Horiuchi A. et al. (2000) Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proc. Natl. Acad. Sci. USA 97: 6809-6814
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6809-6814
-
-
Bibb, J.A.1
Yan, Z.2
Svenningsson, P.3
Snyder, G.L.4
Pieribone, V.A.5
Horiuchi, A.6
-
106
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F., Finkbeiner S., Devys D. and Greenberg M. E. (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95: 55-66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
107
-
-
0025281039
-
Atrophy of the hypothalamic lateral tuberal nucleus in Huntington's disease
-
Kremer H. P., Roos R. A., Dingjan G., Marani E. and Bots G. T. (1990) Atrophy of the hypothalamic lateral tuberal nucleus in Huntington's disease. J. Neuropathol. Exp. Neurol. 49: 371-382
-
(1990)
J. Neuropathol. Exp. Neurol.
, vol.49
, pp. 371-382
-
-
Kremer, H.P.1
Roos, R.A.2
Dingjan, G.3
Marani, E.4
Bots, G.T.5
-
108
-
-
0026077859
-
The hypothalamic lateral tuberal nucleus and the characteristics of neuronal loss in Huntington's disease
-
Kremer H. P., Roos R. A., Dingjan G. M., Bots G. T., Bruyn G. W. and Hofman M. A. (1991) The hypothalamic lateral tuberal nucleus and the characteristics of neuronal loss in Huntington's disease. Neurosci. Lett. 132: 101-104
-
(1991)
Neurosci. Lett.
, vol.132
, pp. 101-104
-
-
Kremer, H.P.1
Roos, R.A.2
Dingjan, G.M.3
Bots, G.T.4
Bruyn, G.W.5
Hofman, M.A.6
-
110
-
-
0034049346
-
An autopsy case with clinically and molecular genetically diagnosed Huntington's disease with only minimal non-specific neuropathological findings
-
Mizuno H., Shibayama H., Tanaka F., Doyu M., Sobue G., Iwata H. et al. (2000) An autopsy case with clinically and molecular genetically diagnosed Huntington's disease with only minimal non-specific neuropathological findings. Clin. Neuropathol. 19: 94-103
-
(2000)
Clin. Neuropathol.
, vol.19
, pp. 94-103
-
-
Mizuno, H.1
Shibayama, H.2
Tanaka, F.3
Doyu, M.4
Sobue, G.5
Iwata, H.6
-
111
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M., Sapp E., Chase K. O., Davies S. W., Bates G. P., Vonsattel J. P. et al. (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277: 1990-1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
-
112
-
-
0021982117
-
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
-
Graveland G. A., Williams R. S. and DiFiglia M. (1985) Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science 227: 770-773
-
(1985)
Science
, vol.227
, pp. 770-773
-
-
Graveland, G.A.1
Williams, R.S.2
DiFiglia, M.3
-
113
-
-
0034994207
-
Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production
-
Guidetti P., Charles V., Chen E. Y., Reddy P. H., Kordower J. H., Whetsell W. O. Jr. et al. (2001) Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production. Exp. Neurol. 169: 340-350
-
(2001)
Exp. Neurol.
, vol.169
, pp. 340-350
-
-
Guidetti, P.1
Charles, V.2
Chen, E.Y.3
Reddy, P.H.4
Kordower, J.H.5
Whetsell Jr., W.O.6
-
115
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
Schilling G., Becher M. W., Sharp A. H., Jinnah H. A., Duan K., Kotzuk J. A. et al. (1999) Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum. Mol. Genet. 8: 397-407
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
-
116
-
-
10744227174
-
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
-
Slow E. J., Van Raamsdonk J., Rogers D., Coleman S. H., Graham R. K., Deng Y. et al. (2003) Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum. Mol. Genet. 12: 1555-1567
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1555-1567
-
-
Slow, E.J.1
Van Raamsdonk, J.2
Rogers, D.3
Coleman, S.H.4
Graham, R.K.5
Deng, Y.6
-
117
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
Reddy P. H., Williams M., Charles V., Garrett L., Pike-Buchanan L., Whetsell W. O. Jr et al. (1998) Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. Nat Genet 20: 198-202
-
(1998)
Nat Genet
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
Garrett, L.4
Pike-Buchanan, L.5
Whetsell Jr., W.O.6
-
118
-
-
19944427749
-
Orexin loss in Huntington's disease
-
Petersen A., Gil J., Maat-Schieman M. L., Bjorkqvist M., Tanila H., Araujo I. M. et al. (2005) Orexin loss in Huntington's disease. Hum. Mol. Genet. 14: 39-47
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 39-47
-
-
Petersen, A.1
Gil, J.2
Maat-Schieman, M.L.3
Bjorkqvist, M.4
Tanila, H.5
Araujo, I.M.6
-
119
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
Luthi-Carter R., Strand A., Peters N. L., Solano S. M., Hollingsworth Z. R., Menon A. S. et al. (2000) Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet. 9: 1259-1271
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
-
120
-
-
0035668684
-
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
-
Bogdanov M. B., Andreassen O. A., Dedeoglu A., Ferrante R. J. and Beal M. F. (2001) Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J. Neurochem. 79: 1246-1249
-
(2001)
J. Neurochem.
, vol.79
, pp. 1246-1249
-
-
Bogdanov, M.B.1
Andreassen, O.A.2
Dedeoglu, A.3
Ferrante, R.J.4
Beal, M.F.5
-
121
-
-
0034915234
-
Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease
-
Santamaria A., Perez-Severiano F., Rodriguez-Martinez E., Maldonado P. D., Pedraza-Chaverri J., Rios C. et al. (2001) Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease. Neurochem. Res. 26: 419-424
-
(2001)
Neurochem. Res.
, vol.26
, pp. 419-424
-
-
Santamaria, A.1
Perez-Severiano, F.2
Rodriguez-Martinez, E.3
Maldonado, P.D.4
Pedraza-Chaverri, J.5
Rios, C.6
-
122
-
-
0033982887
-
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
-
Tabrizi S. J., Workman J., Hart P. E., Mangiarini L., Mahal A., Bates G. et al. (2000) Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. Ann. Neurol. 47: 80-86
-
(2000)
Ann. Neurol.
, vol.47
, pp. 80-86
-
-
Tabrizi, S.J.1
Workman, J.2
Hart, P.E.3
Mangiarini, L.4
Mahal, A.5
Bates, G.6
-
123
-
-
0037183717
-
Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation
-
Perez-Severiano F., Escalante B., Vergara P., Rios C. and Segovia J. (2002) Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation. Brain Res. 951: 36-42
-
(2002)
Brain Res.
, vol.951
, pp. 36-42
-
-
Perez-Severiano, F.1
Escalante, B.2
Vergara, P.3
Rios, C.4
Segovia, J.5
-
124
-
-
0035900181
-
Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: Effects of L-NAME on symptom progression
-
Deckel A. W., Gordinier A., Nuttal D., Tang V., Kuwada C., Freitas R. et al. (2001) Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of L-NAME on symptom progression. Brain Res. 919: 70-81
-
(2001)
Brain Res.
, vol.919
, pp. 70-81
-
-
Deckel, A.W.1
Gordinier, A.2
Nuttal, D.3
Tang, V.4
Kuwada, C.5
Freitas, R.6
-
125
-
-
0037036055
-
Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice
-
Deckel A. W., Tang V., Nuttal D., Gary K. and Elder R. (2002) Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice. Brain Res. 939: 76-86
-
(2002)
Brain Res.
, vol.939
, pp. 76-86
-
-
Deckel, A.W.1
Tang, V.2
Nuttal, D.3
Gary, K.4
Elder, R.5
-
126
-
-
0035364748
-
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
-
Petersen A., Larsen K. E., Behr G. G., Romero N., Przedborski S., Brundin P. et al. (2001) Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration. Hum. Mol. Genet. 10: 1243-1254
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1243-1254
-
-
Petersen, A.1
Larsen, K.E.2
Behr, G.G.3
Romero, N.4
Przedborski, S.5
Brundin, P.6
-
127
-
-
0037322570
-
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease
-
Cepeda C., Hurst R. S., Calvert C. R., Hernandez-Echeagaray E., Nguyen O. K., Jocoy E. et al. (2003) Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease. J. Neurosci. 23: 961-969
-
(2003)
J. Neurosci.
, vol.23
, pp. 961-969
-
-
Cepeda, C.1
Hurst, R.S.2
Calvert, C.R.3
Hernandez-Echeagaray, E.4
Nguyen, O.K.5
Jocoy, E.6
-
128
-
-
0035164743
-
Impaired glutamate uptake in the R6 Huntington's disease transgenic mice
-
Lievens J. C., Woodman B., Mahal A., Spasic-Boscovic O., Samuel D., Kerkerian-Le Goff L. et al. (2001) Impaired glutamate uptake in the R6 Huntington's disease transgenic mice. Neurobiol. Dis. 8: 807-821
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 807-821
-
-
Lievens, J.C.1
Woodman, B.2
Mahal, A.3
Spasic-Boscovic, O.4
Samuel, D.5
Kerkerian-Le Goff, L.6
-
129
-
-
0036074718
-
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease
-
Hickey M. A., Reynolds G. P. and Morton A. J. (2002) The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease. J. Neurochem. 81: 46-59
-
(2002)
J. Neurochem.
, vol.81
, pp. 46-59
-
-
Hickey, M.A.1
Reynolds, G.P.2
Morton, A.J.3
-
130
-
-
0033066942
-
Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation
-
Reynolds G. P., Dalton C. F., Tillery C. L., Mangiarini L., Davies S. W. and Bates G. P. (1999) Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation. J. Neurochem. 72: 1773-1776
-
(1999)
J. Neurochem.
, vol.72
, pp. 1773-1776
-
-
Reynolds, G.P.1
Dalton, C.F.2
Tillery, C.L.3
Mangiarini, L.4
Davies, S.W.5
Bates, G.P.6
-
131
-
-
0037097202
-
Striatal neurochemical changes in transgenic models of Huntington's disease
-
Ariano M. A., Aronin N., Difiglia M., Tagle D. A., Sibley D. R., Leavitt B. R. et al. (2002) Striatal neurochemical changes in transgenic models of Huntington's disease. J. Neurosci. Res. 68: 716-729
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 716-729
-
-
Ariano, M.A.1
Aronin, N.2
Difiglia, M.3
Tagle, D.A.4
Sibley, D.R.5
Leavitt, B.R.6
-
132
-
-
0036736196
-
Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease
-
Yohrling I. G., Jiang G. C., DeJohn M. M., Robertson D. J., Vrana K. E. and Cha J. H. (2002) Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease. J. Neurochem. 82: 1416-1423
-
(2002)
J. Neurochem.
, vol.82
, pp. 1416-1423
-
-
Yohrling, I.G.1
Jiang, G.C.2
DeJohn, M.M.3
Robertson, D.J.4
Vrana, K.E.5
Cha, J.H.6
-
133
-
-
0033614761
-
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease
-
Cha J. H., Frey A. S., Alsdorf S. A., Kerner J. A., Kosinski C. M., Mangiarini L. et al. (1999) Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease. Philos. Trans. R. Soc. Lond. B Biol. Sci. 354: 981-989
-
(1999)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.354
, pp. 981-989
-
-
Cha, J.H.1
Frey, A.S.2
Alsdorf, S.A.3
Kerner, J.A.4
Kosinski, C.M.5
Mangiarini, L.6
-
134
-
-
0034643362
-
Delaying the onset of Huntington's in mice
-
van Dellen A., Blakemore C., Deacon R., York D. and Hannan A. J. (2000) Delaying the onset of Huntington's in mice. Nature 404: 721-722
-
(2000)
Nature
, vol.404
, pp. 721-722
-
-
Van Dellen, A.1
Blakemore, C.2
Deacon, R.3
York, D.4
Hannan, A.J.5
-
135
-
-
12744279625
-
Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: Neuronal selectivity and potential neuroprotective role of HAP1
-
Zucker B., Luthi-Carter R., Kama J. A., Dunah A. W., Stern E. A., Fox J. H. et al. (2005) Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Hum. Mol. Genet. 14: 179-189
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 179-189
-
-
Zucker, B.1
Luthi-Carter, R.2
Kama, J.A.3
Dunah, A.W.4
Stern, E.A.5
Fox, J.H.6
|