Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction

Neurobiology of Disease

Volumn 20, Issue 3, 2005, Pages 673-684

  Smith, Ruben ^a   Petersén, Åsa ^a   Bates, Gillian P ^b   Brundin, Patrik ^a   Li, Jia Yi ^a  

^a LUND UNIVERSITY   (Sweden)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

CAG repeat; Exocytosis; Huntingtin; Huntington's disease; Mouse; Neurodegeneration; Polyglutamine; R6 1; Rabphilin; Synapse; Synaptic dysfunction; Vesicle protein

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; RABPHILIN 3A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CORTEX; BRAIN REGION; COMPARATIVE STUDY; CONTROLLED STUDY; EXOCYTOSIS; GENE EXPRESSION; HUNTINGTON CHOREA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EXOCYTOSIS; HUNTINGTON DISEASE; INCLUSION BODIES; MALE; MICE; MICE, TRANSGENIC; MOVEMENT DISORDERS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PRESYNAPTIC TERMINALS; RNA, MESSENGER; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES; VESICULAR TRANSPORT PROTEINS;

EID: 24344444735     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.05.008     Document Type: Article

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