Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia

Journal of Comparative Neurology

Volumn 390, Issue 1, 1998, Pages 5-19

  Testa, Claudia M ^a   Friberg, Ingrid K ^a   Weiss, Sara W ^a   Standaert, David G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Confocal microscopy; Corticostriatal pathway; Globus pallidus; Neostriatum; Substantia nigra

Indexed keywords

GLUTAMIC ACID; METABOTROPIC RECEPTOR; MICROTUBULE ASSOCIATED PROTEIN 2; OXIDOPAMINE; POLYCLONAL ANTIBODY; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN INJURY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DECORTICATION; DENDRITE; GLOBUS PALLIDUS; IMMUNOHISTOCHEMISTRY; MALE; NEOSTRIATUM; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

EID: 0031930027     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19980105)390:1<5::AID-CNE2>3.0.CO;2-6     Document Type: Article

References (56)

1. 2+ signal transduction. J. Biol. Chem. 267:13361-13368.
2. Albin, R.L., A.B. Young, and J.B. Penney (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci. 12:366-375.
3. Baude, A., Z. Nusser, J.D. Roberts, E. Mulvihill, R.A. Mcllhinney, and P. Somogyi (1993) The metabotropic glutamate receptor (mGluR1a) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11:771-787.
4. Bergman, H., T. Wichmann, and M. DeLong (1990) Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science 249: 1436-1438.
5. Buckley, K., and R.B. Kelly (1985) Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells. J. Cell Biol. 100:1284-1294.
6. Calabresi, P., R. Maj, A. Pisani, N.B. Mercuri, and G. Bernardi (1992) Long-term synaptic depression in the striatum: Physiological and pharmacological characterization. J. Neurosci. 12:4224-4233.
7. Calabresi, P., A. Pisani, N.B. Mercuri, and G. Bernardi (1996) The corticostriatal projection: From synaptic plasticity to dysfunctions of the basal ganglia. Trends Neurosci.19:19-24.
8. Carlin, R.K., D.J. Grab, R.S. Cohen, and P. Siekevitz (1980) Isolation and characterization of postsynaptic densities from various brain regions: Enrichment of different types of postsynaptic densities. J. Cell Biol. 86:831-843.
9. Catania, M.V., H. Desocarraz, J.B. Penney, and A.B. Young (1994) Metabotropic glutamate receptor heterogeneity in rat brain. Mol. Pharmacol. 45:626-636.
10. Cozzi, A., G. Lombardi, P. Leonardi, M. Carfi, and F. Moroni (1996) Modulation of transmitter output "in vivo" by mGluR agents. Neuropharmacology 35:A10.
11. Duvoisin, R.M., C. Zhang, and K. Ramonell (1995) A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J. Neurosci. 15:3075-3083.
12. Feeley-Kearney, J.A., K.A. Frey, and R.L. Albin (1997) Metabotropic glutamate agonist-induced rotation: A pharmacological, FOS immunohistochemical and [14C]-2-deoxyglucose autoradiographic study. J. Neurosci. 17:4415-4425.
13. Fotuhi, M., A.H. Sharp, C.E. Glatt, P.M. Hwang, M. von Krosigk, S.H. Snyder, and T.M. Dawson (1993) Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inosi-tol 1,4,5-trisphosphate receptor in rat brain. J. Neurosci. 13:2001-2012.
14. Grandes, P., J.M. Mateos, D. Rüegg, R. Kuhn, and T. Knöpfel (1994) Differential cellular localization of three splice variants of the mGluR1 metabotropic glutamate receptor in rat cerebellum. Neuroreport 5:2249-2252.
15. Graybiel, A.M. (1990) Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci. 13:244-253.
16. Hampson, D.R., E. Theriault, X.P. Huang, P. Kristensen, D.S. Pickering, J.E. Franck, and E.R. Mulvihill (1994) Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat. Neuroscience 60:325-336.
17. Hollmann, M., and S. Heinemann (1994) Cloned glutamate receptors. Annu. Rev. Neurosci. 17:31-108.
18. Houamed, K.M., J.L. Kuijper, T.L. Gilbert, B.A. Haldeman, P.J. O'Hara, E.R. Mulvihill, W. Almers, and F.S. Hagen (1991) Cloning, expression and gene structure of a G protein-coupled glutamate receptor from rat brain. Science 252:1318-1321.
19. Huber, G., and A. Matus (1984) Differences in the cellular distribution of two microtubule-associated proteins, MAP1 and MAP2, in rat brain. J. Neurosci. 4:151-160.
20. Kerner, J.A., D.G. Standaert, J.B. Penney, A.B. Young, and G.B. Landwehrmeyer (1997) Expression of group I metabotropic receptors by populations of neurons in the rat neostriatum. Mol. Brain Res. 48:259-269.
21. Kim, J.S., R. Hassler, P. Haug, and K.S. Paik (1977) Effect of frontal cortex ablation on striatal glutamic acid level in the rat. Brain Res. 132:370-374.
22. Kosinski, C.M., D.G. Standaert, C.M. Testa, J.B. Penney, and A.B. Young (1997) Dopaminergic neurons in the substantia nigra express a unique splice form of mGluR1. Neurology 48:A324.
23. Laurie, D.J., H. Boddeke, R. Hiltscher, and B. Sommer (1996a) Hmglu(1d), a novel splice variant of the human type I metabotropic glutamate receptor. Eur. J. Pharmacol. 296:R1-R3.
24. Laurie, D.J., R. Hiltsherer, W.W.G. Boddeke, A. Berthele, T. Tölle, K. Seuwen, and B. Sommer (1996b) Distribution and functional analysis of human mGluR1 receptor splice variants. Neuropharmacology 35:A18.
25. Martin, L.J., C.D. Blackstone, R.L. Huganir, and D.L. Price (1992) Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron 9:259-270.
26. Masu, M., Y. Tanabe, K. Tsuchida, R. Shigemoto, and S. Nakanishi (1991) Sequence and expression of a metabotropic glutamate receptor. Nature 349:760-765.
27. McGeer, P.L., E.G. McGeer, U. Scherer, and K. Singh (1977) A glutamatergic corticostriatal path? Brain Res. 128:369-373.
28. Mercuri, N.B., F. Stratta, P. Calabresi, A. Bonchi, and G. Bernard (1993) Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons. Neuroscience 56:399-407.
29. Nakajima, Y., H. Iwakabe, C. Akazawa, H. Nawa, R. Shigemoto, N. Mizuno, and S. Nakanishi (1993) Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268:11868-11873.
30. Nakanishi, S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258:597-603.
31. Nusser, Z., E. Mulvihill, P. Streit, and P. Somogyi (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience 61:421-427.
32. Ohishi, H., R. Shigemoto, S. Nakanishi, and N. Mizuno (1993a) Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience 53:1009-1018.
33. Ohishi, H., R. Shigemoto, S. Nakanishi, and N. Mizuno (1993b) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study. J. Comp. Neurol. 335:252-266.
34. Ohishi, H., M.R. Ogawa, R. Shigemoto, T. Kaneko, S. Nakanishi, and N. Mizuno (1994) Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron 13:55-66.
35. Okamoto, N., S. Hori, C. Akazawa, Y. Hayashi, R. Shigemoto, N. Mizuno, and S. Nakanishi (1994) Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J. Biol. Chem. 269:1231-1236.
36. Parent, A. (1990) Extrinsic connections of the basal ganglia. Trends Neurosci. 13:254-258.
37. Parent, A., and L.N. Hazrati (1995) Functional anatomy of the basal ganglia. 1. The cortico-basal ganglia-thalamo-cortical loop. Brain Res. Rev. 20:91-127.
38. Petralia, R.S., Y.-X. Wang, A.S. Niedzielski, and R.J. Wenthold (1996) The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic, and glial localizations. Neuroscience 71:949-976.
39. Pin, J.-P., and R. Duvoisin (1995) The metabotropic glutamate receptors: Structure and function. Neuropharmacology 34:1-26.
40. Pin, J.-P., C. Waeber, L. Prezeau, J. Bockaert, and S.J. Heinemann (1992) Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 89:10331-10335.
41. Sacaan, A.I., J.A. Monn, and D.D. Schoepp (1991) Intrastriatal injection of a selective metabotropic excitatory amino acid receptor agonist induces contralateral turning in the rat. J. Pharmacol. Exp. Ther. 259:1366-1370.
42. Saugstad, J.A., J.M. Kinzie, E.R. Mulvill, T.P. Segerson, and G.L. Westbrook (1994) Cloning and expression of a new member of the L-2-amino-4-phosphonic acid-sensitive class of metabotropic glutamate receptors. Mol. Pharmacol. 45:367-372.
43. Shigemoto, R., S. Nakanishi, and N. Mizuno (1992) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. J. Comp. Neurol. 322:121-135.
44. Shigemoto, R., A. Kulik, J.D.B. Roberts, H. Ohishi, Z. Nusser, T. Kaneko, and P. Somogyi (1996a) Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone. Nature 381:523-525.
45. Shigemoto, R., H. Ohishi, A. Kinoshita, E. Wada, N. Mizuno, J.D.B. Roberts, and P. Somogyi (1996b) Differential targeting of presynaptic metabotropic glutamate receptors in the rat CNS. Neuropharmacology 35:A28.
46. Standaert, D.G., P. Needleman, and C.B. Saper (1986a) Organization of atriopeptin-like immunoreactive neurons in the central nervous system of the rat. J. Comp. Neurol. 253:315-341.
47. Standaert, D.G., S.J. Watson, R.A. Houghten, and C.B. Saper (1986b) Opioid peptide immunoreactivity in spinal and trigeminal dorsal horn neurons projecting to the parabrachial nucleus. J. Neurosci. 6:1220-1226.
48. Standaert, D.G., C.M. Testa, G. Rudolf, and Z. Hollingsworth (1996) Inhibition of NMDA glutamate receptor subunit expression by antisense oligonucleotides reveals their role in striatal motor regulation. J. Pharmacol. Exp. Ther. 276:342-352.
49. Tanabe, Y., M. Masu, T. Ishii, R. Shigemoto, and S. Nakanishi (1992) A family of metabotropic glutamate receptors. Neuron 8:169-179.
50. Tanabe, Y., A. Nomura, M. Masu, R. Shigemoto, N. Mizuno, and S. Nakanishi (1993) Signal transduction, pharmacologic properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J. Neurosci. 13:1372-1378.
51. Testa, C.M., D.G. Standaert, A.B. Young, and J.B. Penney (1994) Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J. Neurosci. 14:3005-3018.
52. Testa, C.M., D.G. Standaert, G.B. Landwehrmeyer, J.B. Penney, and A.B. Young (1995) Differential expression of the mGluR5 metabotropic glutamate receptor by rat striatal neurons. J. Comp. Neurol. 354:241-252.
53. Wigmore, M.A., A. Abbott, and M.G. Lacey (1996) Functional characterization of mGluRs in ventral midbrain. Neuropharmacology 35:A33.
54. Wüllner, U., D.G. Standaert, C.M. Testa, G.B. Landwehrmeyer, M.V. Catania, J.B. Penney, and A.B. Young (1994a) Glutamate receptor expression in rat striatum: effects of deafferentation. Brain Res. 647:209-219.
55. Wüllner, U., C.M. Testa, M.V. Catania, A.B. Young, and J.B. Penney (1994b) Glutamate receptors in striatum and substantia nigra-Effects of medial forebrain bundle lesions. Brain Res. 645:98-102.
56. Young, A.B., M.B. Bromberg, and J.B. Penney (1981) Decreased glutamate uptake in subcortical areas deafferented by sensorimotor cortical ablation in the cat. J. Neurosci. 1:241-249.