-
6
-
-
0034612255
-
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6809-6814
-
-
Bibb, J.A.1
Yan, Z.2
Svenningsson, P.3
Snyder, G.L.4
Pieribone, V.A.5
Horiuchi, A.6
Nairn, A.C.7
Messer, A.8
Greengard, P.9
-
7
-
-
0033560924
-
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
-
(1999)
J. Neurosci.
, vol.19
, pp. 3248-3257
-
-
Carter, R.J.1
Lione, L.A.2
Humby, T.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
9
-
-
0033614761
-
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease
-
(1999)
Phil. Trans. R. Soc. London B
, vol.354
, pp. 981-989
-
-
Cha, J.H.1
Frey, A.S.2
Alsdorf, S.A.3
Kerner, J.A.4
Kosinski, C.M.5
Mangiarini, L.6
Penney J.B., Jr.7
Davies, S.W.8
Bates, G.P.9
Young, A.B.10
-
10
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
Penney, J.B.7
Bates, G.P.8
Young, A.B.9
-
14
-
-
0001616532
-
Sodium- and potassium-dependent excitatory amino acid transporters in brain plasma membranes
-
O. P. Ottersen & J. Storm-Mathisen, Eds., Elsevier Science, Amsterdam
-
(2000)
Glutamate
, pp. 231-254
-
-
Danbolt, N.C.1
-
18
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
20
-
-
0034047444
-
Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice
-
(2000)
Neuroscience
, vol.98
, pp. 705-713
-
-
Denovan-Wright, E.M.1
Robertson, H.A.2
-
22
-
-
0034081681
-
The pattern of neurodegeneration in Huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
-
(2000)
Neuroscience
, vol.97
, pp. 505-519
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.3
-
23
-
-
0033119123
-
Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
-
(1999)
J. Neurosci.
, vol.19
, pp. 2522-2534
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Mulroy, J.S.4
Kuemmerle, S.5
Jones, R.6
Rye, D.7
Ferrante, R.J.8
Hersch, S.M.9
Li, X.J.10
-
26
-
-
0029910823
-
Brain glutamate transporter proteins form homomultimers
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27715-27722
-
-
Haugeto, O.1
Ullensvang, K.2
Levy, L.M.3
Chaudhry, F.A.4
Honore, T.5
Nielsen, M.6
Lehre, K.P.7
Danbolt, N.C.8
-
27
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
28
-
-
0033136692
-
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.A.3
Leavitt, B.R.4
LePiane, F.5
Singaraja, R.6
Smith, D.J.7
Bissada, N.8
McCutcheon, K.9
Nasir, J.10
Jamot, L.11
Li, X.J.12
Stevens, M.E.13
Rosemond, E.14
Roder, J.C.15
Phillips, A.G.16
Rubin, E.M.17
Hersch, S.M.18
Hayden, M.R.19
-
30
-
-
0032732281
-
Differentiation of substrate and nonsubstrate inhibitor of the high-affinity, sodium-dependent glutamate transporters
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 1095-1104
-
-
Koch, H.P.1
Kavanaugh, M.P.2
Esslinger, C.S.3
Zerangue, N.4
Humphrey, J.M.5
Amara, S.G.6
Chamberlin, A.R.7
Bridges, R.J.8
-
31
-
-
0033178904
-
Glutamate transporter EAAC1 is expressed in neurons and glial cells in the rat nervous system
-
(1999)
Glia
, vol.27
, pp. 129-142
-
-
Kugler, P.1
Schmitt, A.2
-
34
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
Efstratiadis, A.11
Zeitlin, S.12
Chesselet, M.F.13
-
39
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
In Process Citation
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
Ross, C.A.11
Borchelt, D.R.12
Tapscott, S.J.13
Young, A.B.14
Cha, J.H.15
Olson, J.M.16
-
42
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
48
-
-
0026486310
-
Cloning and expression of a rat brain L-glutamate transporter
-
(1992)
Nature
, vol.360
, pp. 464-467
-
-
Pines, G.1
Danbolt, N.C.2
Bjoras, M.3
Zhang, Y.4
Bendahan, A.5
Eide, L.6
Koepsell, H.7
Storm-Mathisen, J.8
Seeberg, E.9
Kanner, B.I.10
-
51
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
(1998)
Nat. Genet.
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
Garrett, L.4
Pike-Buchanan, L.5
Whetsell W.O., Jr.6
Miller, G.7
Tagle, D.A.8
-
53
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
Mangiarini, L.4
Hollenbach, B.5
Hasenbank, R.6
Bates, G.P.7
Davies, S.W.8
Lehrach, H.9
Wanker, E.E.10
-
54
-
-
0033551063
-
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4604-4609
-
-
Scherzinger, E.1
Sittler, A.2
Schweiger, K.3
Heiser, V.4
Lurz, R.5
Hasenbank, R.6
Bates, G.P.7
Lehrach, H.8
Wanker, E.E.9
-
55
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
Slunt, H.H.7
Ratovitski, T.8
Cooper, J.K.9
Jenkins, N.A.10
Copeland, N.G.11
Price, D.L.12
Ross, C.A.13
Borchelt, D.R.14
-
59
-
-
0017614742
-
Glutamic acid and excitatory nerve endings: Reduction of glutamic acid uptake after axotomy
-
(1977)
Brain Res.
, vol.120
, pp. 379-386
-
-
Storm-Mathisen, J.1
-
61
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
(1997)
Science
, vol.276
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
66
-
-
0034163497
-
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 503-513
-
-
Wheeler, V.C.1
White, J.K.2
Gutekunst, C.A.3
Vrbanac, V.4
Weaver, M.5
Li, X.J.6
Li, S.H.7
Yi, H.8
Vonsattel, J.P.9
Gusella, J.F.10
Hersch, S.11
Auerbach, W.12
Joyner, A.L.13
MacDonald, M.E.14
-
68
-
-
0034038270
-
Epidermal growth factor receptor agonists increase expression of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-kappaB
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 667-678
-
-
Zelenaia, O.1
Schlag, B.D.2
Gochenauer, G.E.3
Ganel, R.4
Song, W.5
Beesley, J.S.6
Grinspan, J.B.7
Rothstein, J.D.8
Robinson, M.B.9
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