Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39594-39598

  Goffredo, Donato ^a   Rigamonti, Dorotea ^a   Tartari, Marzia ^a   De Micheli, Alberto ^a   Verderio, Claudia ^a   Matteoli, Michela ^a   Zuccato, Chiara ^a   Cattaneo, Elena ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CALCIUM; CELLS; DISEASES; ENZYMES;

NEURONS;

BIOCHEMISTRY;

3 NITROPROPIONIC ACID; CALCIUM; CALPAIN; GLUTAMIC ACID; HUNTINGTIN;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; HUNTINGTON CHOREA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; RAT;

ANIMALS; BLOTTING, WESTERN; BRAIN; CALCIMYCIN; CALCIUM; CALPAIN; CELL-FREE SYSTEM; CELLS, CULTURED; DENSITOMETRY; GLUTAMIC ACID; IONOPHORES; NERVE TISSUE PROTEINS; NEURONS; NITRO COMPOUNDS; NUCLEAR PROTEINS; PROPIONIC ACIDS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

ANIMALIA;

EID: 0037131263     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C200353200     Document Type: Article

References (31)

1. Rigamonti, D., Bauer, J. H., De-Fraja, C., Conti, L., Sipione, S., Sciorati, C., Clementi, E., Hackam, A., Hayden, M., Li, Y., Ross, C., Govoni, S., Vincenz, C., and Cattaneo, E. (2000) J. Neurosci. 20, 3705-3713
2. Dragatsis, I., Levine, M. S., and Zeitlin, S. (2000) Nat. Genet. 26, 300-306
3. Leavitt, B. R., Guttman, J. A., Hodgson, J. G., Kimel, G. H., Singaraja, R., Vogl, A. W., and Hayden, M. R. (2001) Am. J. Hum. Genet. 68, 313-324
4. Ho, L. W., Brown, R., Maxwell, M., Wyttenbach, A., and Rubinsztein, D. C. (2001) J. Med. Genet. 38, 450-452
5. Rigamonti, D., Sipione, S., Goffredo, D., Zuccato, C., Fossale, E., and Cattaneo, E. (2001) J. Biol. Chem. 276, 14545-14548
6. Huntington's Disease Collaborative Research Group (1993) Cell 72, 971-983
7. Sipione, S., and Cattaneo, E., (2001) Mol. Neurobiol. 23, 21-51
8. Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lehrach, H., and Wanker, E. E. (1997) Cell 90, 549-558
9. Cattaneo, E., Rigamonti, D., Zuccato, C., Goffredo, D., Squitieri, F., and Sipione, S. (2001) Trends Neurosci. 24, 182-188
10. Zuccato, C., Ciammola, A., Rigamonti, D., Leavitt, B. R., Goffredo, D., Conti, L., MacDonald, M. E., Friedlander, R. M., Silani, V., Hayden, M. R., et al. (2001) Science 293, 493-498
11. Wellington, C. L., Singaraja, R., Ellerby, L., Savill, J., Roy, S., Leavitt. B., Cattaneo, E., Hackam, A., Sharp, A., Thornberry, N., Nicholson, D. W., Bredesen, D. E., and Hayden, M. R. (2000) J. Biol. Chem. 275, 19831-19838
12. Kim, M., Lee, H. S., LaForet, G., McIntyre, C., Martin, E. J., Chang, P., Kim, T. W., Williams, M., Reddy, P. H., Tagle, D., Boyce, F. M., Won, L., Heller, A., Aronin, N., and DiFiglia, M. (1999) J. Neurosci. 19, 964-973
13. Ona, V. O., Li, M., Vonsattel, J. P., Andrews, L. J., Khan, S. Q., Chung, W. M., Frey, A. S., Menon, A. S., Li, X. J., Stieg, P. E., Yuan, J., Penney, J. B., Young, A. B., Cha, J. H., and Friedlander, R. M. (1999) Nature 399, 263-267
14. Chen, M., Ona, V. O., Li, M., Ferrante, R. J., Fink, K. B., Zhu, S., Bian, J., Guo, L., Farrell, L. A., Hersch, S. M., Hobbs, W., Vonsattel, J. P., Cha, J. H., and Friedlander, R. M. (2000) Nat. Med. 6, 797-801
15. DiFiglia, M., Sapp E., Chase, K. O., Davies, S. W., Bates, G. P., Vonsattel, J. P., and Aronin, N. (1997) Science, 277, 1990-1993
16. Mende-Mueller, L. M., Toneff, T., Hwang, S. R., Chesselet, M. F., and Hook, V. Y. (2001) J. Neurosci. 21, 1830-1837
17. Kim, Y. J., Yi, Y., Sapp, E., Wang, Y., Cuiffo, B., Kegel, K. B., Qin, Z. H., Aronin, N., and DiFiglia, M. (2001) Proc. Natl. Acad. Sci. U. S. A., 98, 12784-12789
18. Wang, K. K. (2000) Trends Neurosci. 23, 20-26
19. Chan, S. L., and Mattson, M. P. (1999) J. Neurosci. Res. 58, 167-190
20. Alho, H., Ferrarese, C., Vicini, S., and Vaccarino, F. (1988) Brain Res. 467, 193-204
21. Wellington, C. L., Ellerby, L. M., Hackam, A. S., Margolis, R. L., Trifiro, M. A., Singaraja, R., McCutcheon, K., Salvesen, G. S., Propp, S. S., Bromm, M., et al. (1998) J. Biol. Chem., 273, 9158-9167
22. Grunewald, T., and Beal, M. F. (1999) Ann. N. Y. Acad. Sci. 893, 203-213
23. Cepeda, C., Ariano, M. A., Calvert, C. R., Flores-Hernandez, J., Chandler, S. H., Leavitt, B. R., Hayden, M. R., and Levine, M. S. (2001) J. Neurosci. Res. 66, 525-539
24. Hansson, O., Guatteo, E., Mercuri, N. B., Bernardi, G., Li, X. J., Castilho, R. F., and Brundin, P. (2001) Eur. J. Neurosci. 14, 1492-1504
25. Hodgson, J. G., Agopyan, N., Gutekunst, C. A., Leavitt, B. R., LePiane, F., Singaraja, R., Smith, D. J., Bissada, N., McCutcheon, K., Nasir, J., Jamot, L., Li, X. J., Stevens, M. E., Rosemond, E., Roder, J. C., Phillips, A. G., Rubin, E. M., Hersch, S. M., and Hayden, M. R. (1999) Neuron 23, 181-192
26. Guttmann, R. P., Baker, D. L., Seifert, K. M., Cohen, A. S., Coulter, D. A., and Lynch, D. R. (2001) J. Neurochem. 78, 1083-1093
27. Kumar, U., Asotra, K., Patel, S. C., and Patel, Y. C. (1997) Exp. Neurol. 145, 412-424
28. Ferrante, R. J., Kowall, N. W., and Richardson, E. P., Jr. (1991) J. Neurosci. 11, 3877-3887
29. Panov, A. V., Gutekunst, C. A., Leavitt, B. R., Hayden, M. R., Burke, J. R., Strittmatter, W. J., and Greenamyre, J. T. (2002) Nat. Neurosci. 5, 731-736
30. Saito, K., Elce, J. S., Hamos, J. E., and Nixon, R. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2628-2632
31. Gervais, F. G., Singaraja, R., Xanthoudakis, S., Gutekunst, C. A., Leavitt, B. R., Metzler, M., Hackam, A. S., Tam, J., Vaillancourt, J. P., Houtzager, V., Rasper, D. M., Roy, S., Hayden, M. R., and Nicholson, D. W. (2002) Nat. Cell Biol. 4, 95-105