-
1
-
-
0026609559
-
Alternative excitotoxic hypotheses
-
Albin, R. L. & Greenamyre, J. T. 1992 Alternative excitotoxic hypotheses. Neurology 42, 733-738.
-
(1992)
Neurology
, vol.42
, pp. 733-738
-
-
Albin, R.L.1
Greenamyre, J.T.2
-
2
-
-
0025322132
-
Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease
-
Albin, R. L., Young, A. B., Penney, J. B., Handelin, B., Balfour, R., Anderson, K. D., Markel, D. S., Tourtellotte, W. W. & Reiner, A. 1990 Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. New Engl. J. Med. 322, 1293-1298.
-
(1990)
New Engl. J. Med.
, vol.322
, pp. 1293-1298
-
-
Albin, R.L.1
Young, A.B.2
Penney, J.B.3
Handelin, B.4
Balfour, R.5
Anderson, K.D.6
Markel, D.S.7
Tourtellotte, W.W.8
Reiner, A.9
-
3
-
-
12644252940
-
2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease
-
2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease. Brain 119, 2085-2095.
-
(1996)
Brain
, vol.119
, pp. 2085-2095
-
-
Antonini, A.1
-
4
-
-
0029926199
-
Reduction in enkephalin and substance P messenger RNA in the striatum of early grade Huntington's disease: A detailed cellular in situ hybridization study
-
Augood, S. J., Faull, R. L. M., Love, D. R. & Emson, P. C. 1996 Reduction in enkephalin and substance P messenger RNA in the striatum of early grade Huntington's disease: a detailed cellular in situ hybridization study. Neuroscience 72, 1023-1036.
-
(1996)
Neuroscience
, vol.72
, pp. 1023-1036
-
-
Augood, S.J.1
Faull, R.L.M.2
Love, D.R.3
Emson, P.C.4
-
5
-
-
0030612119
-
2 receptor gene expression in the striatum in Huntington's disease
-
2 receptor gene expression in the striatum in Huntington's disease. Ann. Neurol. 42, 215-221.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 215-221
-
-
Augood, S.J.1
Faull, R.L.M.2
Emson, P.C.3
-
6
-
-
0022446150
-
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
-
Beal, M. F., Kowall, N. W., Ellison, D. W., Mazurek, M. F., Swartz, K. J. & Martin, J. B. 1986 Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321, 168-171.
-
(1986)
Nature
, vol.321
, pp. 168-171
-
-
Beal, M.F.1
Kowall, N.W.2
Ellison, D.W.3
Mazurek, M.F.4
Swartz, K.J.5
Martin, J.B.6
-
7
-
-
0032540437
-
HAP1 huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice
-
Bertaux, F., Sharp, A. H., Ross, C. A., Lehrach, H., Bates, G. P. & Wanker, E. 1998 HAP1 huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice. FEBS Lett. 426, 229-232.
-
(1998)
FEBS Lett.
, vol.426
, pp. 229-232
-
-
Bertaux, F.1
Sharp, A.H.2
Ross, C.A.3
Lehrach, H.4
Bates, G.P.5
Wanker, E.6
-
10
-
-
0027066115
-
Multiple states of rat brain (RS)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography
-
Cha, J.-H. J., Makowiec, R. L., Penney, J. B. & Young, A. B. 1992 Multiple states of rat brain (RS)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography. Mol. Pharmacol. 41, 832-838.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 832-838
-
-
Cha, J.-H.J.1
Makowiec, R.L.2
Penney, J.B.3
Young, A.B.4
-
11
-
-
0032568517
-
Altered brain neurotransmitter receptors in trangenic mice expressing a portion of an abnormal human Huntington disease gene
-
Cha, J.-H. J., Kosinski, C. M., Kerner, J. A., Alsdorf, S. A., Mangiarini, L., Davies, S. W., Penney, J. B., Bates, G. P. & Young, A. B. 1998 Altered brain neurotransmitter receptors in trangenic mice expressing a portion of an abnormal human Huntington disease gene. Proc. Natl Acad. Sci. USA 95, 6480-6485.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6480-6485
-
-
Cha, J.-H.J.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
Penney, J.B.7
Bates, G.P.8
Young, A.B.9
-
12
-
-
0025195594
-
B binding sites in rat central nervous system: A quantitative autoradiographic study
-
B binding sites in rat central nervous system: a quantitative autoradiographic study. Neuroscience 34, 341-357.
-
(1990)
Neuroscience
, vol.34
, pp. 341-357
-
-
Chu, D.C.1
Albin, R.L.2
Young, A.B.3
Penney, J.B.4
-
14
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies, S. W., Turmaine, M., Cozens, B. A., DiFiglia, M., Sharp, A. H., Ross, C. A., Scherzinger, E., Wanker, E. E., Mangiarini, L. & Bates, G. P. 1997 Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 90, 537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
15
-
-
0032501740
-
Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?
-
Davies, S. W., Beardsall, K., Turmaine, M., DiFiglia, M., Aronin, N. & Bates, G. P. 1998 Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions? Lancet 351, 131-133.
-
(1998)
Lancet
, vol.351
, pp. 131-133
-
-
Davies, S.W.1
Beardsall, K.2
Turmaine, M.3
DiFiglia, M.4
Aronin, N.5
Bates, G.P.6
-
16
-
-
0023750525
-
Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
-
de la Monte, S. M., Vonsattel, J.-P. & Richardson Jr, E. P. 1988 Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J. Neuropathol. Exp. Neurol. 47, 516-525.
-
(1988)
J. Neuropathol. Exp. Neurol.
, vol.47
, pp. 516-525
-
-
De La Monte, S.M.1
Vonsattel, J.-P.2
Richardson E P., Jr.3
-
17
-
-
0025363346
-
Excitotoxic injury of the neostriatum: A model for Huntington's disease
-
DiFiglia, M. 1990 Excitotoxic injury of the neostriatum: a model for Huntington's disease. Trends Neurosci. 13, 286-289.
-
(1990)
Trends Neurosci.
, vol.13
, pp. 286-289
-
-
DiFiglia, M.1
-
18
-
-
0028989602
-
Huntingtin is a cytoplasmic protein asociated with vesicles in human and rat brain neurons
-
DiFiglia, M. (and 11 others) 1995 Huntingtin is a cytoplasmic protein asociated with vesicles in human and rat brain neurons. Neuron 14, 1075-1081.
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
DiFiglia, M.1
-
19
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia, M., Sapp, E., Chase, K. O., Davies, S.W., Bates, G. P., Vonsattel, J. P. & Aronin, N. 1997 Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277, 1990-1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
20
-
-
0025718650
-
Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease
-
Dure IV, L. S., Young, A. B. & Penney, J. B. 1991 Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease. Ann. Neurol. 30, 785-793.
-
(1991)
Ann. Neurol.
, vol.30
, pp. 785-793
-
-
Dure L.S. IV1
Young, A.B.2
Penney, J.B.3
-
22
-
-
0021848538
-
Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate-and kainate-sensitive glutamate binding sites
-
Greenamyre, J. T., Olson, J. M. M., Penney, J. B. & Young, A. B. 1985 Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate-and kainate-sensitive glutamate binding sites. J. Pharmacol. Exp. Ther. 233, 254-263.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 254-263
-
-
Greenamyre, J.T.1
Olson, J.M.M.2
Penney, J.B.3
Young, A.B.4
-
23
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is unstable in Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group 1993 A novel gene containing a trinucleotide repeat that is unstable in Huntington's disease chromosomes. Cell 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
25
-
-
0020644707
-
3H]Mazindol binding associated with neuronal dopamine uptake sites in corpus stratum membranes
-
3H]Mazindol binding associated with neuronal dopamine uptake sites in corpus stratum membranes. Eur. J. Pharmacol. 90, 461-462.
-
(1983)
Eur. J. Pharmacol.
, vol.90
, pp. 461-462
-
-
Javitch, J.A.1
Blaustein, R.D.2
Snyder, S.H.3
-
26
-
-
0344431341
-
Structural neurology: Are seeds at the root of neuronal degeneration?
-
Lansbury Jr, P. T. 1997 Structural neurology: are seeds at the root of neuronal degeneration? Neuron 19, 1151-1154.
-
(1997)
Neuron
, vol.19
, pp. 1151-1154
-
-
Lansbury P.T., Jr.1
-
27
-
-
0019384474
-
Decreased receptor-binding sites for kainic acid in brains of patients with Huntington's disease
-
London, E. D., Yamamura, H. I., Bird, E. D. & Coyle, J. T. 1981 Decreased receptor-binding sites for kainic acid in brains of patients with Huntington's disease. Biol. Psychiat. 16, 155-162.
-
(1981)
Biol. Psychiat.
, vol.16
, pp. 155-162
-
-
London, E.D.1
Yamamura, H.I.2
Bird, E.D.3
Coyle, J.T.4
-
28
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini, L. (and 10 others) 1996 Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87, 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
-
29
-
-
0025853692
-
Adenosine A2 receptors: Selective localization in the human basal ganglia and alterations with disease
-
Martinez-Mir, M. I., Probst, A. & Palacios, J. M. 1991 Adenosine A2 receptors: selective localization in the human basal ganglia and alterations with disease. Neuroscience 42, 697-706.
-
(1991)
Neuroscience
, vol.42
, pp. 697-706
-
-
Martinez-Mir, M.I.1
Probst, A.2
Palacios, J.M.3
-
30
-
-
0029968460
-
Trinucleotide repeats in neurogenetic disorders
-
Paulson, H. L. & Fischbeck, K. H. 1996 Trinucleotide repeats in neurogenetic disorders. A. Rev. Neurosci. 19, 79-107.
-
(1996)
A. Rev. Neurosci.
, vol.19
, pp. 79-107
-
-
Paulson, H.L.1
Fischbeck, K.H.2
-
31
-
-
0020445836
-
Quantitative autoradiography of neurotransmitter receptors in Huntington's disease
-
Penney, J. B. & Young, A. B. 1982 Quantitative autoradiography of neurotransmitter receptors in Huntington's disease. Neurology 32, 1391-1395.
-
(1982)
Neurology
, vol.32
, pp. 1391-1395
-
-
Penney, J.B.1
Young, A.B.2
-
32
-
-
0030470459
-
Glutamine repeats and inherited neurode-generative diseases: Molecular aspects
-
Perutz, M. F. 1996 Glutamine repeats and inherited neurode-generative diseases: molecular aspects. Curr. Opin. Struct. Biol. 6, 848-858.
-
(1996)
Curr. Opin. Struct. Biol.
, vol.6
, pp. 848-858
-
-
Perutz, M.F.1
-
33
-
-
0028283985
-
Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
-
Perutz, M. F., Johnson, T., Suzuki, M. & Finch, J. T. 1994 Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases. Proc. Natl Acad. Sci. USA 91, 5355-5358.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 5355-5358
-
-
Perutz, M.F.1
Johnson, T.2
Suzuki, M.3
Finch, J.T.4
-
34
-
-
0030985156
-
The complex pathology of trinucleotide repeats
-
Reddy, R. S. & Housman, D. E. 1997 The complex pathology of trinucleotide repeats. Curr. Opin. Cell Biol. 9, 364-372.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 364-372
-
-
Reddy, R.S.1
Housman, D.E.2
-
35
-
-
0017669877
-
Alterations in dopaminergic receptors in Huntington's disease
-
Reisine, T. D., Fields, J. Z., Stern, L. Z., Johnson, P. C., Bird, E. D. & Yamamura, H. I. 1977 Alterations in dopaminergic receptors in Huntington's disease. Life Sci. 21, 1123-1128.
-
(1977)
Life Sci.
, vol.21
, pp. 1123-1128
-
-
Reisine, T.D.1
Fields, J.Z.2
Stern, L.Z.3
Johnson, P.C.4
Bird, E.D.5
Yamamura, H.I.6
-
36
-
-
0022930504
-
2 dopamine receptor autoradiography: High percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections
-
2 dopamine receptor autoradiography: high percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections. Brain Res. 383, 121-128.
-
(1986)
Brain Res.
, vol.383
, pp. 121-128
-
-
Richfield, E.K.1
Young, A.B.2
Penney, J.B.3
-
37
-
-
0026062661
-
Heterogeneous dopamine receptor changes in early and late Huntington's disease
-
Richfield, E. K., O'Brien, C. F., Eskin, T. & Shoulson, I. 1991 Heterogeneous dopamine receptor changes in early and late Huntington's disease. Neurosci. Lett. 132, 121-126.
-
(1991)
Neurosci. Lett.
, vol.132
, pp. 121-126
-
-
Richfield, E.K.1
O'Brien, C.F.2
Eskin, T.3
Shoulson, I.4
-
38
-
-
0002885477
-
Neuronal nuclear cytoplasmic changes in Huntington's chorea: Electron microscope investigations
-
(ed. T. N. Chase, N. S. Wexler & A. Barbeau), New York: Raven Press
-
Roizin, L., Stellar, S. & Liu, J. C. 1979 Neuronal nuclear cytoplasmic changes in Huntington's chorea: electron microscope investigations. In Advances in neurology, vol. 23 (ed. T. N. Chase, N. S. Wexler & A. Barbeau), pp. 95-122. New York: Raven Press.
-
(1979)
Advances in Neurology
, vol.23
, pp. 95-122
-
-
Roizin, L.1
Stellar, S.2
Liu, J.C.3
-
39
-
-
0031446233
-
Intranuclear neuronal inclusions: A common mechanism for glutamine-repeat neurodegenerative diseases?
-
Ross, C. A. 1997 Intranuclear neuronal inclusions: a common mechanism for glutamine-repeat neurodegenerative diseases? Neuron 19, 1147-1150.
-
(1997)
Neuron
, vol.19
, pp. 1147-1150
-
-
Ross, C.A.1
-
40
-
-
0030771894
-
Huntingtin localization in brains of normal and Huntington's disease patients
-
Sapp, E., Schwarz, C., Chase, K., Bhide, P. G., Young, A. B., Penney, J., Vonsattel, J. P., Aronin, N. & DiFiglia, M. 1997 Huntingtin localization in brains of normal and Huntington's disease patients. Ann. Neurol. 42, 604-612.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 604-612
-
-
Sapp, E.1
Schwarz, C.2
Chase, K.3
Bhide, P.G.4
Young, A.B.5
Penney, J.6
Vonsattel, J.P.7
Aronin, N.8
DiFiglia, M.9
-
41
-
-
0030298003
-
Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex, and hippocampus
-
Standaert, D. G., Landwehrmeyer, G. B., Kerner, J. A., Penney Jr, J. B. & Young, A. B. 1996 Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex, and hippocampus. Mol. Brain Res. 42, 89-102.
-
(1996)
Mol. Brain Res.
, vol.42
, pp. 89-102
-
-
Standaert, D.G.1
Landwehrmeyer, G.B.2
Kerner, J.A.3
Penney J.B., Jr.4
Young, A.B.5
-
42
-
-
0020062980
-
γ-aminobutyric acid receptors in normal human brain and Huntington disease
-
Van Ness, P. C., Watkins, A. E., Bergman, M. O., Tourtellotte, W. W. & Olsen, R. W. 1982 γ-aminobutyric acid receptors in normal human brain and Huntington disease. Neurology 32, 63-68.
-
(1982)
Neurology
, vol.32
, pp. 63-68
-
-
Van Ness, P.C.1
Watkins, A.E.2
Bergman, M.O.3
Tourtellotte, W.W.4
Olsen, R.W.5
-
43
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel, J. P., Myers, R. H., Stevens, T. J., Ferrante, R. J., Bird, E. D. & Richardson, E. P. 1985 Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 44, 559-577.
-
(1985)
J. Neuropathol. Exp. Neurol.
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson, E.P.6
-
44
-
-
0021132283
-
Benzodiazepine receptors in early Huntington's disease
-
Walker, F. O., Young, A. B., Penney, J. B., Dorovini-Zis, K. & Shoulson, I. 1984 Benzodiazepine receptors in early Huntington's disease. Neurology 34, 1237-1240.
-
(1984)
Neurology
, vol.34
, pp. 1237-1240
-
-
Walker, F.O.1
Young, A.B.2
Penney, J.B.3
Dorovini-Zis, K.4
Shoulson, I.5
-
46
-
-
0028235644
-
Glutamate receptor expression in rat striatum: Effect of deafferentation
-
Wüllner, U., Standaert, D. G., Testa, C. M., Landwehrmeyer, G. B., Catania, M. V., Penney Jr, J. B. & Young, A. B. 1994 Glutamate receptor expression in rat striatum: effect of deafferentation. Brain Res. 647, 209-219.
-
(1994)
Brain Res.
, vol.647
, pp. 209-219
-
-
Wüllner, U.1
Standaert, D.G.2
Testa, C.M.3
Landwehrmeyer, G.B.4
Catania, M.V.5
Penney J.B., Jr.6
Young, A.B.7
-
47
-
-
0023690166
-
NMDA receptor losses in putamen from patients with Huntington's disease
-
Young, A. B., Greenamyre, J. T., Hollingsworth, Z., Albin, R., D'Amato, C., Shoulson, I. & Penney, J. B. 1988 NMDA receptor losses in putamen from patients with Huntington's disease. Science 241, 981-983.
-
(1988)
Science
, vol.241
, pp. 981-983
-
-
Young, A.B.1
Greenamyre, J.T.2
Hollingsworth, Z.3
Albin, R.4
D'Amato, C.5
Shoulson, I.6
Penney, J.B.7
|