Interaction of Huntingtin-associated protein with dynactin P150(Glued)

Journal of Neuroscience

Volumn 18, Issue 4, 1998, Pages 1261-1269

  Li, Shi Hua ^a   Gutekunst, Claire Anne ^a   Hersch, Steven M ^b   Li, Xiao Jiang ^a,b  

^a Departments of Genetics   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dynactin; Huntingtin; Huntington's disease; Intracellular transport; Microtubule; Targeting

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CYTOSOL; DROSOPHILA; ENZYME ACTIVITY; GENE EXPRESSION; HUNTINGTON CHOREA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; INTRACELLULAR TRANSPORT; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; YEAST;

EID: 0032519646     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-04-01261.1998     Document Type: Article

References (6)

1. Albin RL, Tagle DA (1995) Genetics and molecular biology of Huntington's disease. Trends Neurosci 18:11-14.
2. Allan V (1994) Organelle movement. Dynactin: portrait of a dynein regulator. Curr Biol 4:1000-1002.
3. Bao J, Sharp AH, Wagster M V, Becher M, Schilling G, Ross CA, Dawson VL, Dawson TM (1996) Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. Proc Natl Acad Sci USA 93:5037-5042.
4. Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M (1996) Expression of normal and mutant huntingtin in the developing brain. J Neurosci 16:5523-5535.
5. Brady ST (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317:73-75.
6. Brady ST, Pfister KK, Bloom GS (1990) A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proc Natl Acad Sci USA 87:1061-1065.