Decreased cAMP response element-mediated transcription. An early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis

Journal of Biological Chemistry

Volumn 279, Issue 6, 2004, Pages 4988-4999

  Sugars, Katharine L ^a   Brown, Rosemary ^a   Cook, Lynnette J ^a   Swartz, Jina ^a   Rubinsztein, David C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; DISEASES; GENETIC ENGINEERING; NEUROLOGY; PATHOLOGY; PROTEINS;

MUTANTS;

BIOCHEMISTRY;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HUNTINGTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POLYGLUTAMINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL DEATH; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; EXON; GENE INDUCTION; HUNTINGTON CHOREA; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; TRANSGENE;

ANIMALS; APOPTOSIS; COS CELLS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EXONS; HUMANS; HUNTINGTON DISEASE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PC12 CELLS; PEPTIDE FRAGMENTS; PEPTIDES; RATS; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 1042289730     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310226200     Document Type: Article

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