Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 6, 2000, Pages 2898-2903

  Wyttenbach, Andreas ^a   Carmichael, Jenny ^a   Swartz, Jina ^a   Furlong, Robert A ^a   Narain, Yolanda ^a   Rankin, Julia ^a   Rubinsztein, David C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 40; HUNTINGTIN; LACTACYSTIN; MUTANT PROTEIN; POLYGLUTAMINE; PROTEASOME;

ANIMAL CELL; ARTICLE; CELL INCLUSION; CONTROLLED STUDY; DNA TRANSFECTION; HEAT SHOCK; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEINASE INHIBITION; STRAIN DIFFERENCE;

ACETYLCYSTEINE; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL DEATH; COS CELLS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; EXONS; HEAT-SHOCK PROTEINS; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; MULTIENZYME COMPLEXES; PEPTIDES; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; TEMPERATURE; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MAMMALIA;

EID: 0034646426     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.6.2898     Document Type: Article

References (36)

1. Perutz, M. F. (1999) Trend Biochem. Sci. 24, 58-63.
2. Rubinsztein, D. C., Wyttenbach, A. & Rankin, J. (1999) J. Med. Genet. 36, 265-270.
3. DiFiglia, M., Sapp, E., Chase, K. O., Davies, S. W., Bates, G. P., Vonsattel, J. P. & Aronin, N. (1997) Science 277, 1990-1993.
4. Li, M., Miwa, S., Kobayashi, Y., Merry, D. E., Yamamoto, M., Tanaka, F., Doyu, M., Hashizume, Y., Fischbeck, K. H. & Sobue, G. (1998) Ann. Neurol. 44, 249-254.
5. Igarashi, S., Koide, R., Shimohata, T., Yamada, M., Hayashi, Y., Takano, H., Date, H., Oyake, M., Sato, T., Sato, A., et al. (1998) Nat. Genet 18, 111-117.
6. Skinner, P. J., Koshy B. T., Cummings, C. J., Klement, I. A., Helin, K., Servadio, A., Zoghbi, H. Y. & Orr, H. T. (1997) Nature (London) 389, 971-978.
7. Paulson, H. L., Perez, M. K., Trottier, Y., Trojanowski, J. Q., Subramony, S. H., Das, S. S., Vig, P., Mandel, J. L., Fischbeck, K. H. & Pittman, R. N. (1997) Neuron 19, 333-344.
8. Holmberg, M., Duyckaerts, C., Durr, A., Cancel, G., Gourfinkel-An, I., Damier, P., Faucheux, B., Trottier, Y., Hirsch, E. C., Agid, Y., et al. (1998) Hum. Mol. Gen. 7, 913-918.
9. Becher, M. W., Koztuk, J. A., Sharp, A. H., Davies, S. W., Bates, G. B., Price, D. L. & Ross, C. A. (1997) Neurobiol. Dis. 4, 1-11.
10. Davies, S. W., Turmaine, M., Cozens, B. A., DiFiglia, M., Sharp, A. H., Ross, C. A., Scherzinger, E., Wanker, E. E., Mangiarini, L. & Bates, G. P. (1997) Cell 90, 537-548.
11. Martindale, D., Hackam, A., Wieczorek, A., Ellerby, L., Wellington, C., McCutcheon, K., Singaraja, R., Kazemi-Esfarjani, P., Devon, R., Kim, S. U., et al. (1998) Nat. Genet. 18, 150-154.
12. Cooper, J. K., Schilling G., Peters, M. F., Herring, W. J., Sharp, A. H., Kaminsky, Z., Masone, J., Khan, F. A., Delanoy, M., Borchelt, D. R., et al. (1998) Hum. Mol. Genet. 7, 783-790.
13. Sato, A., Shimohata, T., Koide, R., Takano, H., Sato, T., Oyake, M., Igarashi, S., Tanaka, K., Inuzuka, T., Nawa, H., et al. (1999) Hum. Mol. Genet. 8, 997-1006.
14. Ellerby, L. M., Hackam, A. S., Proop, S. S., Ellerby, H. M., Rabizadeh, S., Cashman, N. R., Trifiro, M. A., Pinsky, L., Wellington, C. L., Salvesen, G. S., et al. (1999) J. Neurochem. 72, 185-195.
15. Sadou, F., Finkbeiner, S., Devys, D. & Greenberg, M. E. (1998) Cell 95, 55-66.
16. Klement, I. A., Skinner, P. J., Kayfor, M. D., Yi, H., Hersch, S. M., Clark, H. B., Zoghbi, H. Y. & Orr, H. T. (1998) Cell 95, 41-53.
17. Orr, H. T., Skinner, P. A., Klement, C. J., Cummings, C. J. & Zoghbi, H. J. (1998) Am. J. Hum. Genet. Suppl., A8.
18. Hackam, A. S., Singaraja, R., Wellington, C. L., Metzler, M., McCutcheon, K., Zhang, T., Kalchman, M. & Hayden, M. R. (1998) J. Cell Biol. 141, 1097-1105.
19. Cummings, C. J., Mancini, M. A., Antalffy, B., DeFranco, D. B., Orr, H. T. & Zoghbi, H. Y. (1998) Nat. Genet. 19, 148-154.
20. Chai, Y., Koppenhafer, S. L., Shoesmith, S. J., Perez, M. K. & Paulson, H. L. (1999) Hum. Mol. Genet. 8, 673-682.
21. Stenoinen, D. L, Cummings, C. J., Adams, H. P., Mancini, M. G., Patel, K., DeMartino, G. N., Marcelli, M., Weigel, N. L. & Mancini, M. A. (1999) Hum. Mol. Genet. 8, 731-741.
22. Hochstrasser, M. (1996) Annu. Rev. Genet. 30, 405-439.
23. Coux, D., Tanaka, K. & Goldberg, A. L. (1996) Annu. Rev. Biochem. 65, 801-847.
24. Glover, J. R. & Lindquist, S. (1998) Cell 94, 73-82.
25. Hartl, F. U. (1996) Nature (London) 381, 571-580.
26. Hendricks, J. P. & Hartl, F. U. (1993) Annu. Rev. Biochem. 62, 349-384.
27. Lu, Z. & Cyr, D. M. (1998) J. Biol. Chem. 273, 1970-5978.
28. Morimoto, R. I, Kline, M. P., Bimston, D. N. & Cotto, J. J (1997) Essays Biochem. 32, 17-29.
29. Bush, K. T., Goldberg, A. L. & Nigam, S. K. (1997) J. Biol. Chem. 272, 9086-9092.
30. Kim, D., Kim, S. H. & Li, G. C. (1999) Biochem. Biophys. Res. Commun. 254, 264-268.
31. Kawazoe, Y., Nakai A., Tanabe, M. & Nagata, K. (1998) Eur. J. Biochem. 255, 356-362.
32. Lunkes, A. & Mandel, J. L. (1998) Hum. Mol Genet. 7, 1355-1361.
33. Schilling G., Becher, M. W., Sharp, A. H., Jinnah, H. A., Duan, K., Kotzuk, J. A., Slunt, H. H., Ratovitski, T., Cooper, J. K., Jenkins, N. A., et al. (1999) Hum. Mol. Genet. 8, 397-407.
34. Beck, S. C., Paidas, C. N., Tan, H., Yang, J. & De Maio, A. (1995) Am. J. Physiol. 269, R608-R613.
35. Newnam, G. P., Wegrzyn, R. D., Lindquist, S. L. & Chernoff, Y. O (1999) Mol. Cell. Biol. 19, 1325-1333.
36. Cyr, D. M., Langer, T. & Douglas, M. G. (1994) Trends Biochem. Sci. 19, 176-181.