Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

Journal of Biological Chemistry

Volumn 278, Issue 4, 2003, Pages 2081-2084

  Eckman, Elizabeth A ^b   Watson, Mona ^b   Marlow, Laura ^b   Sambamurti, Kumar ^b   Eckman, Christopher B ^a  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; DISEASES; ENZYMES; PHYSIOLOGY;

PATHOGENESIS;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN CONVERTING ENZYME 2; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; ENDOTHELIN-CONVERTING ENZYME 1; METALLOPROTEINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE MUTATION; GENOTYPE; IMMUNOBLOTTING; MOUSE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; WESTERN BLOTTING;

ANIMALIA;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASPARTIC ENDOPEPTIDASES; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; METALLOENDOPEPTIDASES; MICE; MICE, KNOCKOUT; PROTEIN STRUCTURE, TERTIARY;

EID: 0037462769     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C200642200     Document Type: Article

References (46)

1. Iwata, N., Tsubuki, S., Takaki, Y., Watanabe, K., Sekiguchi, M., Hosoki, E., Kawashima-Morishima, M., Lee, H. J., Hama, E., Sekine-Aizawa, Y., and Saido, T. C. (2000) Nat. Med. 6, 143-150
2. Qiu, W. Q., Walsh, D. M., Ye, Z., Vekrellis, K., Zhang, J., Podlisny, M. B., Rosner, M. R., Safavi, A., Hersh, L. B., and Selkoe, D. J. (1998) J. Biol. Chem. 273, 32730-32738
3. Vekrellis, K., Ye, Z., Qiu, W. Q., Walsh, D., Hartley, D., Chesneau, V., Rosner, M. R., and Selkoe, D. J. (2000) J. Neurosci. 20, 1657-1665
4. Chesneau, V., Vekrellis, K., Rosner, M. R., and Selkoe, D. J. (2000) Biochem. J. 351, 509-516
5. Iwata, N., Tsubuki, S., Takaki, Y., Shirotani, K., Lu, B., Gerard, N. P., Gerard, C., Hama, E., Lee, H. J., and Saido, T. C. (2001) Science 292, 1550-1552
6. Van Nostrand, W. E., and Porter, M. (1999) Biochemistry 38, 11570-11576
7. Tucker, H. M., Kihiko, M., Caldwell, J. N., Wright, S., Kawarabayashi, T., Price, D., Walker, D., Scheff, S., McGillis, J. P., Rydel, R. E., and Estus, S. (2000) J. Neurosci. 20, 3937-3946
8. Ledesma, M. D., Da Silva, J. S., Crassaerts, K., Delacourte, A., De Strooper, B., and Dotti, C. G. (2000) EMBO Rep. 1, 530-535
9. Exley, C., and Korchazhkina, O. V. (2001) Neuroreport 12, 2967-2970
10. Tucker, H. M., Kihiko-Ehmann, M., and Estus, S. (2002) J. Neurosci. Res. 70, 249-255
11. Hu, J., Igarashi, A., Kamata, M., and Nakagawa, H. (2001) J. Biol. Chem. 276, 47863-47868
12. Backstrom, J. R., Lim, G. P., Cullen, M. J., and Tokes, Z. A. (1996) J. Neurosci. 16, 7910-7919
13. Yamin, R., Malgeri, E. G., Sloane, J. A., McGraw, W. T., and Abraham, C. R. (1999) J. Biol. Chem. 274, 18777-18784
14. Qiu, W. Q., Borth, W., Ye, Z., Haass, C., Teplow, D. B., and Selkoe, D. J. (1996) J. Biol. Chem. 271, 8443-8451
15. Selkoe, D. J. (2001) Neuron 32, 177-180
16. Eckman, E. A., Reed, D. K., and Eckman, C. B. (2001) J. Biol. Chem. 276, 24540-24548
17. Turner, A. J., and Murphy, L. J. (1996) Biochem. Pharmacol. 51, 91-102
18. Xu, D., Emoto, N., Giaid, A., Slaughter, C., Kaw, S., deWit, D., and Yanagisawa, M. (1994) Cell 78, 473-485
19. Davenport, A. P., Kuc, R. E., Plumpton, C., Mockridge, J. W., Barker, P. J., and Huskisson, N. S. (1998) Histochem. J. 30, 359-374
20. Korth, P., Bohle, R. M., Corvol, P., and Pinet, F. (1999) J. Histochem. Cytochem. 47, 447-462
21. Barnes, K., Walkden, B. J., Wilkinson, T. C., and Turner, A. J. (1997) J. Neurochem. 68, 570-577
22. Sluck, J. M., Lin, R. C., Katolik, L. I., Jeng, A. Y., and Lehmann, J. C. (1999) Neuroscience 91, 1483-1497
23. Nakagomi, S., Kiryu-Seo, S., and Kiyama, H. (2000) Neuroscience 101, 441-449
24. Emoto, N., and Yanagisawa, M. (1995) J. Biol. Chem. 270, 15262-15268
25. Yanagisawa, H., Hammer, R. E., Richardson, J. A., Emoto, N., Williams, S. C., Takeda, S., Clouthier, D. E., and Yanagisawa, M. (2000) J. Clin. Invest. 105, 1373-1382
26. Yanagisawa, H., Yanagisawa, M., Kapur, R. P., Richardson, J. A., Williams, S. C., Clouthier, D. E., de Wit, D., Emoto, N., and Hammer, R. E. (1998) Development 125, 825-836
27. Savage, M. J., Trusko, S. P., Howland, D. S., Pinsker, L. R., Mistretta, S., Reaume, A. G., Greenberg, B. D., Siman, R., and Scott, R. W. (1998) J. Neurosci. 18, 1743-1752
28. Petanceska, S. S., Nagy, V., Frail, D., and Gandy, S. (2000) Neurology 54, 2212-2217
29. Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Nat. Med. 2, 864-870
30. Pinnix, I., Musunuru, U., Tun, H., Sridharan, A., Golde, T., Eckman, C., Ziani-Cherif, C., Onstead, L., and Sambamurti, K. (2001) J. Biol. Chem. 276, 481-487
31. Borchelt, D. R., Ratovitski, T., van Lare, J., Lee, M. K., Gonzales, V., Jenkins, N. A., Copeland, N. G., Price, D. L., and Sisodia, S. S. (1997) Neuron 19, 939-945
32. Borchelt, D. R., Thinakaran, G., Eckman, C. B., Lee, M. K., Davenport, F., Ratovitsky, T., Prada, C. M., Kim, G., Seekins, S., Yager, D., Slunt, H. H., Wang, R., Seeger, M., Levey, A. I., Gandy, S. E., Copeland, N. G., Jenkins, N. A., Price, D. L., Younkin, S. G., and Sisodia, S. S. (1996) Neuron 17, 1005-1013
33. Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., St George Hyslop, P., and Selkoe, D. J. (1997) Nat. Med. 3, 67-72
34. De Jonghe, C., Cruts, M., Rogaeva, E. A., Tysoe, C., Singleton, A., Vanderstichele, H., Meschino, W., Dermaut, B., Vanderhoeven, I., Backhovens, H., Vanmechelen, E., Morris, C. M., Hardy, J., Rubinsztein, D. C., St George-Hyslop, P. H., and Van Broeckhoven, C. (1999) Hum. Mol. Genet. 8, 1529-1540
35. Flood, D. G., Reaume, A. G., Dorfman, K. S., Lin, Y. G., Lang, D. M., Trusko, S. P., Savage, M. J., Annaert, W. G., De Strooper, B., Siman, R., and Scott, R. W. (2002) Neurobiol. Aging 23, 335-348
36. Nakano, Y., Kondoh, G., Kudo, T., Imaizumi, K., Kato, M., Miyazaki, J. I., Tohyama, M., Takeda, J., and Takeda, M. (1999) Eur. J. Neurosci. 11, 2577-2581
37. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., and Cole, G. (1996) Science 274, 99-102
38. Poduslo, S. E., Yin, X., Hargis, J., Brumback, R. A., Mastrianni, J. A., and Schwankhaus, J. (1999) Hum. Genet. 105, 32-37
39. Lorenzo, M. N., Khan, R. Y., Wang, Y., Tai, S. C., Chan, G. C., Cheung, A. H., and Marsden, P. A. (2001) Biochim. Biophys. Acta 1522, 46-52
40. Tanzi, R. E., Kovacs, D. M., Kim, T. W., Moir, R. D., Guenette, S. Y., and Wasco, W. (1996) Neurobiol. Dis. 3, 159-168
41. Gray, G. A., and Webb, D. J. (1996) Pharmacol. Ther. 72, 109-148
42. Loffler, B. M. (2000) J. Cardiovasc. Pharmacol. 35, Suppl. 2, S79-S82
43. Kitas, E. A., Loffler, B. M., Daetwyler, S., Dehmlow, H., and Aebi, J. D. (2002) Bioorg. Med. Chem. Lett. 12, 1727-1730
44. Telemaque, S., Emoto, N., deWit, D., and Yanagisawa, M. (1998) J. Cardiovasc. Pharmacol. 31, Suppl. 1, S548-S550
45. Hoang, M. V., and Turner, A. J. (1997) Biochem. J. 327, 23-26
46. Johnson, G. D., Stevenson, T., and Ahn, K. (1999) J. Biol. Chem. 274, 4053-4058