Isoform-Specific Knockout of FE65 Leads to Impaired Learning and Memory

Journal of Neuroscience Research

Volumn 75, Issue 1, 2004, Pages 12-24

  Wang, Baiping ^a   Hu, Qubai ^a   Hearn, Mark G ^b   Shimizu, Kimiko ^c   Ware, Carol B ^a   Liggitt, Dennis H ^a   Jin, Lee Way ^a   Cool, Bethany H ^a   Storm, Daniel R ^c   Martin, George M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative translation; Alzheimer's disease; Beta amyloid precursor protein; FE65; Morris water maze; Passive avoidance; Transgenic mice

Indexed keywords

PEPTIDE; PROTEIN; PROTEIN FE65; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENE TARGETING; HIPPOCAMPUS; KNOCKOUT MOUSE; LEARNING; LEARNING DISORDER; MAZE TEST; MEMORY DISORDER; MOLECULAR WEIGHT; MOUSE; MOUSE MUTANT; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RNA TRANSLATION; SPATIAL MEMORY; TASK PERFORMANCE; WESTERN BLOTTING; WILD TYPE;

AGING; AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; CEREBRAL CORTEX; ELECTROSHOCK; FEMALE; INDOLES; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, KNOCKOUT; MOLECULAR STRUCTURE; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; PSYCHOMOTOR PERFORMANCE; REACTION TIME; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SWIMMING; TIME FACTORS; TRANSFECTION; VOCALIZATION, ANIMAL;

EID: 9144262348     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10834     Document Type: Article

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