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Volumn 55, Issue 3, 2003, Pages 463-508

The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 METHOXYAMPHETAMINE; AMINE OXIDASE (FLAVIN CONTAINING); AMPHETAMINE DERIVATIVE; BRAIN MONOAMINE; CHLORAMPHETAMINE; DOPAMINE; FENFLURAMINE; FREE RADICAL; MESCALINE; METHAMPHETAMINE; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; NORADRENALIN; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

EID: 0041466261     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: 10.1124/pr.55.3.3     Document Type: Review
Times cited : (982)

References (414)
  • 1
    • 0032502639 scopus 로고    scopus 로고
    • 1A receptor density and 8-OH-DPAT-induced hypothermia: Blockade by drugs preventing 5-hydroxytryptamine depletion
    • 1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion. Eur J Pharmacol 346:181-188.
    • (1998) Eur J Pharmacol , vol.346 , pp. 181-188
    • Aguirre, N.1    Ballaz, S.2    Lasheras, B.3    Del Río, J.4
  • 2
    • 0032161183 scopus 로고    scopus 로고
    • The role of dopaminergic systems in the perinatal sensitivity to 3,4-methylenedioxyamphetamine-induced neurotoxicity in rats
    • Aguirre N, Barrionuevo M, Lasheras B, and Del Rio J (1998b) The role of dopaminergic systems in the perinatal sensitivity to 3,4-methylenedioxyamphetamine-induced neurotoxicity in rats. J Pharmacol Exp Ther 286:1159-1165.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1159-1165
    • Aguirre, N.1    Barrionuevo, M.2    Lasheras, B.3    Del Rio, J.4
  • 3
    • 0033607450 scopus 로고    scopus 로고
    • Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity
    • Aguirre N, Barrionuevo M, Ramirez MJ, Del Rio J, and Lasheras B (1999) Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity. Neuroreport 10:3675-3680.
    • (1999) Neuroreport , vol.10 , pp. 3675-3680
    • Aguirre, N.1    Barrionuevo, M.2    Ramirez, M.J.3    Del Rio, J.4    Lasheras, B.5
  • 5
    • 0031847891 scopus 로고    scopus 로고
    • Effects of 7-nitroindazole, an NOS inhibitor on methamphetamine-induced dopaminergic and serotonergic neurotoxicity in mice
    • Ali SF and Itzhak Y (1998) Effects of 7-nitroindazole, an NOS inhibitor on methamphetamine-induced dopaminergic and serotonergic neurotoxicity in mice. Ann NY Acad Sci 844:122-130.
    • (1998) Ann NY Acad Sci , vol.844 , pp. 122-130
    • Ali, S.F.1    Itzhak, Y.2
  • 6
    • 0035933453 scopus 로고    scopus 로고
    • Effects of methylenedioxymethamphetamine on noradrenaline-evoked contractions of rat right ventricle and small mesenteric artery
    • Al-Sahli W, Ahman H, Kheradmand F, Connolly C, and Docherty JR (2001) Effects of methylenedioxymethamphetamine on noradrenaline-evoked contractions of rat right ventricle and small mesenteric artery. Eur J Pharmacol 422:169-174.
    • (2001) Eur J Pharmacol , vol.422 , pp. 169-174
    • Al-Sahli, W.1    Ahman, H.2    Kheradmand, F.3    Connolly, C.4    Docherty, J.R.5
  • 7
    • 0023714185 scopus 로고
    • Anorectic activities of serotonin uptake inhibitors: Correlation with their potencies at inhibiting serotonin uptake in vivo and 3H-mazindol binding in vitro
    • Angel I, Taranger MA, Claustre Y, Scatton B, and Langer SZ (1988) Anorectic activities of serotonin uptake inhibitors: correlation with their potencies at inhibiting serotonin uptake in vivo and 3H-mazindol binding in vitro. Life Sci 43:651-658.
    • (1988) Life Sci , vol.43 , pp. 651-658
    • Angel, I.1    Taranger, M.A.2    Claustre, Y.3    Scatton, B.4    Langer, S.Z.5
  • 8
    • 0043027747 scopus 로고
    • Amphetamine toxicity in aggregated mice
    • Askew BM (1961) Amphetamine toxicity in aggregated mice. J Pharm Pharmacol 13:701-703.
    • (1961) J Pharm Pharmacol , vol.13 , pp. 701-703
    • Askew, B.M.1
  • 9
    • 24544456303 scopus 로고    scopus 로고
    • MDMA induces localised increases in arc mRNA expression in rat brain in a dose-dependent fashion
    • Aston JC, Beveridge TJR, and Elliott JM (2002) MDMA induces localised increases in arc mRNA expression in rat brain in a dose-dependent fashion. Br J Pharmacol 134:65P
    • (2002) Br J Pharmacol , vol.134
    • Aston, J.C.1    Beveridge, T.J.R.2    Elliott, J.M.3
  • 10
    • 24544451337 scopus 로고    scopus 로고
    • Paroxetine modulates the expression of the immediate early gene arc induced by MDMA in rat brain
    • Aston JC and Elliott JM (2002) Paroxetine modulates the expression of the immediate early gene arc induced by MDMA in rat brain. Br J Pharmacol 135:346P.
    • (2002) Br J Pharmacol , vol.135
    • Aston, J.C.1    Elliott, J.M.2
  • 11
    • 0036720775 scopus 로고    scopus 로고
    • Changes in cardiovascular responsiveness and cardiotoxicity elicited during binge administration of ecstasy
    • Badon LA, Hicks A, Lord K, Ogden BA, Meleg-Smith S, and Varner KJ (2002) Changes in cardiovascular responsiveness and cardiotoxicity elicited during binge administration of ecstasy. J Pharmacol Exp Ther 302:898-907.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 898-907
    • Badon, L.A.1    Hicks, A.2    Lord, K.3    Ogden, B.A.4    Meleg-Smith, S.5    Varner, K.J.6
  • 12
    • 0034933347 scopus 로고    scopus 로고
    • Serotonergic neurotoxicity of 3,4-(±)-methylenedioxyamphetamine and 3,4-(±)-methylenedioxymethamphetamine (ecstasy) is potentiated by inhibition of γ-glutamyl transpeptidase
    • Bai F, Jones DC, Lau SS, and Monks TJ (2001) Serotonergic neurotoxicity of 3,4-(±)-methylenedioxyamphetamine and 3,4-(±)-methylenedioxymethamphetamine (Ecstasy) is potentiated by inhibition of γ-glutamyl transpeptidase. Chem Res Toxicol 14:863-870.
    • (2001) Chem Res Toxicol , vol.14 , pp. 863-870
    • Bai, F.1    Jones, D.C.2    Lau, S.S.3    Monks, T.J.4
  • 13
    • 0033386744 scopus 로고    scopus 로고
    • Glutathione and N-acetylcysteine conjugates of α-methyldopamine produce serotonergic neurotoxicity: Possible role in methylenedioxymethamphetamine-mediated neurotoxicity
    • Bai F, Lau SS, and Monks TJ (1999) Glutathione and N-acetylcysteine conjugates of α-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxymethamphetamine-mediated neurotoxicity. Chem Res Toxicol 12:1150-1157.
    • (1999) Chem Res Toxicol , vol.12 , pp. 1150-1157
    • Bai, F.1    Lau, S.S.2    Monks, T.J.3
  • 15
    • 0027450090 scopus 로고
    • "Ecstasy" ingestion: A case report of severe complications
    • Barrett PJ and Taylor GT (1993) "Ecstasy" ingestion: a case report of severe complications. J R Soc Med 86:233-234.
    • (1993) J R Soc Med , vol.86 , pp. 233-234
    • Barrett, P.J.1    Taylor, G.T.2
  • 16
    • 0023914535 scopus 로고
    • Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites
    • Battaglia G, Brooks BP, Kulsakdinun C, and De Souza EB (1988) Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites. Eur J Pharmacol 149:159-163.
    • (1988) Eur J Pharmacol , vol.149 , pp. 159-163
    • Battaglia, G.1    Brooks, B.P.2    Kulsakdinun, C.3    De Souza, E.B.4
  • 17
    • 0025817030 scopus 로고
    • Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine) assessment using quantitative autoradiography
    • Battaglia G, Sharkey J, Kuhar MJ, and De Souza EB (1991) Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine) assessment using quantitative autoradiography. Synapse 8:249-260.
    • (1991) Synapse , vol.8 , pp. 249-260
    • Battaglia, G.1    Sharkey, J.2    Kuhar, M.J.3    De Souza, E.B.4
  • 19
    • 0000900320 scopus 로고
    • MDMA effects in brain: Pharmacologic profile and evidence of neurotoxicity from neurochemical and autoradiographic studies
    • (Peroutka SJ ed), Kluwer Academic Publishers, Norwalk, MA
    • Battaglia G, Zaczek R, and De Souza EB (1990) MDMA effects in brain: pharmacologic profile and evidence of neurotoxicity from neurochemical and autoradiographic studies, in Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA (Peroutka SJ ed) pp 171-190, Kluwer Academic Publishers, Norwalk, MA.
    • (1990) Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA , pp. 171-190
    • Battaglia, G.1    Zaczek, R.2    De Souza, E.B.3
  • 21
    • 0026534558 scopus 로고
    • The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine
    • Berger UV, Gu XF, and Azmitia EC (1992) The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine. Eur J Pharmacol 215:153-160.
    • (1992) Eur J Pharmacol , vol.215 , pp. 153-160
    • Berger, U.V.1    Gu, X.F.2    Azmitia, E.C.3
  • 22
    • 0035013041 scopus 로고    scopus 로고
    • Recreational use of 3,4-methylenedioxymethamphetamine (MDMA) or "ecstasy": Evidence for cognitive impairment
    • Bhattachary S and Powell JH (2001) Recreational use of 3,4-methylenedioxymethamphetamine (MDMA) or "ecstasy": evidence for cognitive impairment. Psychol Med 31:647-658.
    • (2001) Psychol Med , vol.31 , pp. 647-658
    • Bhattachary, S.1    Powell, J.H.2
  • 23
    • 0031842014 scopus 로고    scopus 로고
    • Anxiogenic activity of methylenedioxymethamphetamine (ecstasy) - An experimental study
    • Bhattacharya SK, Bhattacharya A, and Ghosal S (1998) Anxiogenic activity of methylenedioxymethamphetamine (ecstasy) - an experimental study. Biog Amines 14:217-237.
    • (1998) Biog Amines , vol.14 , pp. 217-237
    • Bhattacharya, S.K.1    Bhattacharya, A.2    Ghosal, S.3
  • 24
    • 0035976631 scopus 로고    scopus 로고
    • MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro
    • Biello SM and Dafters RI (2001) MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro. Brain Res 920:202-209.
    • (2001) Brain Res , vol.920 , pp. 202-209
    • Biello, S.M.1    Dafters, R.I.2
  • 25
    • 0031648790 scopus 로고    scopus 로고
    • Memory impairment in abstinent MDMA ("ecstasy") users
    • Bolla KI, McCann UD, and Ricaurte GA (1998) Memory impairment in abstinent MDMA ("Ecstasy") users. Neurology 51:1532-1537.
    • (1998) Neurology , vol.51 , pp. 1532-1537
    • Bolla, K.I.1    McCann, U.D.2    Ricaurte, G.A.3
  • 26
    • 0037174806 scopus 로고    scopus 로고
    • MDMA- and p-chlorophenylalanine-induced reduction in 5-HT concentrations: Effects on serotonin transporter densities
    • Boot BP, Mechan AO, McCann UD, and Ricaurte GA (2002) MDMA- and p-chlorophenylalanine-induced reduction in 5-HT concentrations: effects on serotonin transporter densities. Eur J Pharmacol 453:239-244.
    • (2002) Eur J Pharmacol , vol.453 , pp. 239-244
    • Boot, B.P.1    Mechan, A.O.2    McCann, U.D.3    Ricaurte, G.A.4
  • 28
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups and pharmacological studies
    • Braff DL, Geyer MA, and Swerdlow NR (2001) Human studies of prepulse inhibition of startle: normal subjects, patient groups and pharmacological studies. Psychopharmacology 156:234-258.
    • (2001) Psychopharmacology , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 29
    • 0036688073 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in MDMA intracerebral self-administration in rats
    • Braida D and Sala M (2002) Role of the endocannabinoid system in MDMA intracerebral self-administration in rats. Br J Pharmacol 136:1089-1092.
    • (2002) Br J Pharmacol , vol.136 , pp. 1089-1092
    • Braida, D.1    Sala, M.2
  • 30
    • 0028043767 scopus 로고
    • Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine
    • Broening HW, Bacon L, and Slikker W Jr (1994) Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 271:285-293.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 285-293
    • Broening, H.W.1    Bacon, L.2    Slikker W., Jr.3
  • 31
    • 0028856659 scopus 로고
    • Age-dependent sensitivity of rats to the long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response
    • Broening HW, Bowyer JF, and Slikker W Jr (1995) Age-dependent sensitivity of rats to the long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response. J Pharmacol Exp Ther 275:325-333.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 325-333
    • Broening, H.W.1    Bowyer, J.F.2    Slikker W., Jr.3
  • 32
    • 0035341510 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (ecstasy)-induced learning and memory impairments depend on the age of exposure during early development
    • Broening HW, Morford LL, Inman-Wood SL, Fukumura M, and Vorhees CV (2001) 3,4-Methylenedioxymethamphetamine (ecstasy)-induced learning and memory impairments depend on the age of exposure during early development. J Neurosci 21:3228-3235.
    • (2001) J Neurosci , vol.21 , pp. 3228-3235
    • Broening, H.W.1    Morford, L.L.2    Inman-Wood, S.L.3    Fukumura, M.4    Vorhees, C.V.5
  • 33
    • 0029028776 scopus 로고
    • Effects of sulpiride and SCH 23390 on methamphetamine-induced changes in body temperature and lethality
    • Bronstein DM and Hong J-S (1995) Effects of sulpiride and SCH 23390 on methamphetamine-induced changes in body temperature and lethality. J Pharmacol Exp Ther 274:943-950.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 943-950
    • Bronstein, D.M.1    Hong, J.-S.2
  • 34
    • 0023192367 scopus 로고
    • Multiple severe complications from recreational ingestion of MDMA ("ecstasy")
    • Brown C and Osterloh J (1987) Multiple severe complications from recreational ingestion of MDMA ("Ecstasy"). J Am Med Assoc 258:780-781.
    • (1987) J Am Med Assoc , vol.258 , pp. 780-781
    • Brown, C.1    Osterloh, J.2
  • 36
    • 0030447505 scopus 로고    scopus 로고
    • Effects of ecstasy on aldosterone secretion in the rat in vivo and in vitro
    • Burns N, Olverman HJ, Kelly PA, and Williams BC (1996) Effects of ecstasy on aldosterone secretion in the rat in vivo and in vitro. Endocr Res 2:601-606.
    • (1996) Endocr Res , vol.2 , pp. 601-606
    • Burns, N.1    Olverman, H.J.2    Kelly, P.A.3    Williams, B.C.4
  • 37
    • 0033937035 scopus 로고    scopus 로고
    • MDMA and learning: Effects of acute and neurotoxic exposure in the rat
    • Byrne T, Baker LE, and Poling A (2000) MDMA and learning: effects of acute and neurotoxic exposure in the rat. Pharmacol Biochem Behav 66:501-508.
    • (2000) Pharmacol Biochem Behav , vol.66 , pp. 501-508
    • Byrne, T.1    Baker, L.E.2    Poling, A.3
  • 38
    • 0027978346 scopus 로고
    • CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA)
    • Cadet JL, Ladenheim B, Baum I, Carlson E, and Epstein C (1994) CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA). Brain Res 655:259-262.
    • (1994) Brain Res , vol.655 , pp. 259-262
    • Cadet, J.L.1    Ladenheim, B.2    Baum, I.3    Carlson, E.4    Epstein, C.5
  • 39
    • 0029126705 scopus 로고
    • Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): Evidence from using CuZn-superoxide dismutase transgenic mice
    • Cadet JL, Ladenheim B, Hirata H, Rothman RB, Ali S, Carlson E, Epstein C, and Moran TH (1995) Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice. Synapse 21:169-176.
    • (1995) Synapse , vol.21 , pp. 169-176
    • Cadet, J.L.1    Ladenheim, B.2    Hirata, H.3    Rothman, R.B.4    Ali, S.5    Carlson, E.6    Epstein, C.7    Moran, T.H.8
  • 40
    • 0034936397 scopus 로고    scopus 로고
    • Involvement of free radicals in MDMA-induced neurotoxicity in mice
    • Cadet J-L, Thiriet N, and Jayanthi S (2001) Involvement of free radicals in MDMA-induced neurotoxicity in mice. Ann Med Interne 152:1S57-1S59.
    • (2001) Ann Med Interne , vol.152
    • Cadet, J.-L.1    Thiriet, N.2    Jayanthi, S.3
  • 41
    • 0035077417 scopus 로고    scopus 로고
    • Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine
    • Callahan BT, Cord BJ, and Ricaurte GA (2001) Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine. Synapse 40:113-121.
    • (2001) Synapse , vol.40 , pp. 113-121
    • Callahan, B.T.1    Cord, B.J.2    Ricaurte, G.A.3
  • 42
    • 0032563588 scopus 로고    scopus 로고
    • Effect of 7-nitroindazole on body temperature and methamphetamine-induced dopamine toxicity
    • Callahan BT and Ricaurte GA (1998) Effect of 7-nitroindazole on body temperature and methamphetamine-induced dopamine toxicity. Neuroreport 9:2691-2695.
    • (1998) Neuroreport , vol.9 , pp. 2691-2695
    • Callahan, B.T.1    Ricaurte, G.A.2
  • 43
    • 0025108906 scopus 로고
    • Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats
    • Callaway CW, Wing LL, and Geyer MA (1990) Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats. J Pharmacol Exp Ther 254:456-464.
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 456-464
    • Callaway, C.W.1    Wing, L.L.2    Geyer, M.A.3
  • 44
    • 0036315898 scopus 로고    scopus 로고
    • Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")-induced dopamine release and free radical formation in the mouse striatum
    • Camarero J, Sanchez V, O'Shea E, Green AR, and Colado MI (2002) Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")-induced dopamine release and free radical formation in the mouse striatum. J Neurochem 81:961-972.
    • (2002) J Neurochem , vol.81 , pp. 961-972
    • Camarero, J.1    Sanchez, V.2    O'Shea, E.3    Green, A.R.4    Colado, M.I.5
  • 45
    • 0035214357 scopus 로고    scopus 로고
    • In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA
    • Cannon DM, Keenan AK, Guiry PJ, Buon C, Baird AW, and McBean GJ (2001) In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA. Br J Pharmacol 134:1455-1460.
    • (2001) Br J Pharmacol , vol.134 , pp. 1455-1460
    • Cannon, D.M.1    Keenan, A.K.2    Guiry, P.J.3    Buon, C.4    Baird, A.W.5    McBean, G.J.6
  • 46
    • 0036214775 scopus 로고    scopus 로고
    • Effect of 3,4-methylenedioxymethamphetamine ("ecstasy") on body temperature and liver antioxidant status in mice: Influence of ambient temperature
    • Carvalho M, Carvalho F, Remiao F, Pereira ML, Pires-das-Neves R, and Bastos ML (2002) Effect of 3,4-methylenedioxymethamphetamine ("ecstasy") on body temperature and liver antioxidant status in mice: influence of ambient temperature. Arch Toxicol 76:166-172.
    • (2002) Arch Toxicol , vol.76 , pp. 166-172
    • Carvalho, M.1    Carvalho, F.2    Remiao, F.3    Pereira, M.L.4    Pires-das-Neves, R.5    Bastos, M.L.6
  • 47
    • 0025730305 scopus 로고
    • Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia
    • Chadwick IS, Linsley A, Freemont AJ, and Doran B (1991) Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia. J R Soc Med 84:371.
    • (1991) J R Soc Med , vol.84 , pp. 371
    • Chadwick, I.S.1    Linsley, A.2    Freemont, A.J.3    Doran, B.4
  • 48
    • 84872641620 scopus 로고
    • Aggregation as a factor influencing the toxicity of sympathomimetic amines in mice
    • Chance MRA (1946) Aggregation as a factor influencing the toxicity of sympathomimetic amines in mice. J Pharmacol Exp Ther 87:214-219.
    • (1946) J Pharmacol Exp Ther , vol.87 , pp. 214-219
    • Chance, M.R.A.1
  • 49
    • 0000940667 scopus 로고
    • Factors influencing the toxicity of sympathomimetic amines to solitary mice
    • Chance MRA (1947) Factors influencing the toxicity of sympathomimetic amines to solitary mice. J Pharmacol Exp Ther 89:289-296.
    • (1947) J Pharmacol Exp Ther , vol.89 , pp. 289-296
    • Chance, M.R.A.1
  • 50
    • 0032850840 scopus 로고    scopus 로고
    • 1H MRS alterations in recreational 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users
    • 1H MRS alterations in recreational 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") users. J Magn Reson Imaging 10:521-526.
    • (1999) J Magn Reson Imaging , vol.10 , pp. 521-526
    • Chang, L.1    Ernst, T.2    Grob, C.S.3    Poland, R.E.4
  • 51
    • 0034723753 scopus 로고    scopus 로고
    • Effect of ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] on cerebral blood flow: A co-registered SPECT and MRI study
    • Chang L, Grob CS, Ernst T, Itti L, Mishkin FS, Jose-Melchor R, and Poland RE (2000) Effect of ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] on cerebral blood flow: a co-registered SPECT and MRI study. Psychiatry Res 98:15-28.
    • (2000) Psychiatry Res , vol.98 , pp. 15-28
    • Chang, L.1    Grob, C.S.2    Ernst, T.3    Itti, L.4    Mishkin, F.S.5    Jose-Melchor, R.6    Poland, R.E.7
  • 53
    • 0028895035 scopus 로고
    • Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity
    • Che S, Johnson M, Hanson GR, and Gibb JW (1995) Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity. Eur J Pharmacol 293:447-453.
    • (1995) Eur J Pharmacol , vol.293 , pp. 447-453
    • Che, S.1    Johnson, M.2    Hanson, G.R.3    Gibb, J.W.4
  • 54
    • 0034654327 scopus 로고    scopus 로고
    • Amphetamine designer drugs - An overview and epidemiology
    • Christophersen AS (2000) Amphetamine designer drugs - an overview and epidemiology. Toxicol Lett (Shannon) 112-113:127-131.
    • (2000) Toxicol Lett (Shannon) , vol.112-113 , pp. 127-131
    • Christophersen, A.S.1
  • 55
    • 0029916656 scopus 로고    scopus 로고
    • Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion
    • Chu T, Kumagai Y, Distefano EW, and Cho AK (1996) Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion. Biochem Pharmacol 51:789-796.
    • (1996) Biochem Pharmacol , vol.51 , pp. 789-796
    • Chu, T.1    Kumagai, Y.2    Distefano, E.W.3    Cho, A.K.4
  • 57
    • 0030293754 scopus 로고    scopus 로고
    • Serotonin in the regulation of brain microcirculation
    • Cohen Z, Bonvento G, Lacombe P, and Hamel E (1996) Serotonin in the regulation of brain microcirculation. Prog Neurobiol 50:335-362.
    • (1996) Prog Neurobiol , vol.50 , pp. 335-362
    • Cohen, Z.1    Bonvento, G.2    Lacombe, P.3    Hamel, E.4
  • 58
    • 0035679302 scopus 로고    scopus 로고
    • A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on dopamine neurones in mouse brain
    • Colado MI, Camarero J, Mechan AO, Sanchez V, Esteban B, Elliott JM, and Green AR (2001) A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on dopamine neurones in mouse brain. Br J Pharmacol 134:1711-1723.
    • (2001) Br J Pharmacol , vol.134 , pp. 1711-1723
    • Colado, M.I.1    Camarero, J.2    Mechan, A.O.3    Sanchez, V.4    Esteban, B.5    Elliott, J.M.6    Green, A.R.7
  • 59
    • 0032893307 scopus 로고    scopus 로고
    • Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration
    • Colado MI, Esteban B, O'Shea E, Granados R, and Green AR (1999c) Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration. Psychopharmacology 142:421-425.
    • (1999) Psychopharmacology , vol.142 , pp. 421-425
    • Colado, M.I.1    Esteban, B.2    O'Shea, E.3    Granados, R.4    Green, A.R.5
  • 60
    • 0031746324 scopus 로고    scopus 로고
    • Role of hyperthermia in the protective action of chlomethiazole against MDMA ("ecstasy")-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR
    • Colado MI, Granados R, O'Shea E, Esteban B, and Green AR (1998) Role of hyperthermia in the protective action of chlomethiazole against MDMA ("ecstasy")-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR. Br J Pharmacol 194:479-484.
    • (1998) Br J Pharmacol , vol.194 , pp. 479-484
    • Colado, M.I.1    Granados, R.2    O'Shea, E.3    Esteban, B.4    Green, A.R.5
  • 61
    • 0028331550 scopus 로고
    • A study of the mechanism of MDMA ("ecstasy")-induced neurotoxicity of 5-HT neurons using chlormethiazole, dizocilpine and other protective compounds
    • Colado MI and Green AR (1994) A study of the mechanism of MDMA ("Ecstasy")-induced neurotoxicity of 5-HT neurons using chlormethiazole, dizocilpine and other protective compounds. Br J Pharmacol 111:131-136.
    • (1994) Br J Pharmacol , vol.111 , pp. 131-136
    • Colado, M.I.1    Green, A.R.2
  • 62
    • 0029006196 scopus 로고
    • The spin trap reagent α-phenyl-N-tert-butyl nitrone prevents "ecstasy"-induced neurodegeneration of 5-hydroxytryptamine neurons
    • Colado MI and Green AR (1995) The spin trap reagent α-phenyl-N-tert-butyl nitrone prevents "ecstasy"-induced neurodegeneration of 5-hydroxytryptamine neurons. Eur J Pharmacol 280:343-346.
    • (1995) Eur J Pharmacol , vol.280 , pp. 343-346
    • Colado, M.I.1    Green, A.R.2
  • 63
    • 0027462464 scopus 로고
    • 5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine
    • Colado MI, Murray TK, and Green AR (1993) 5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine. Br J Pharmacol 108:583-589.
    • (1993) Br J Pharmacol , vol.108 , pp. 583-589
    • Colado, M.I.1    Murray, T.K.2    Green, A.R.3
  • 64
    • 0032969675 scopus 로고    scopus 로고
    • In vivo evidence against chlomethiazole being neuroprotective against MDMA ("ecstasy")-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism
    • Colado MI, O'Shea E, Esteban B, Granados R, and Green AR (1999b) In vivo evidence against chlomethiazole being neuroprotective against MDMA ("ecstasy")-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism. Neuropharmacology 38:307-314.
    • (1999) Neuropharmacology , vol.38 , pp. 307-314
    • Colado, M.I.1    O'Shea, E.2    Esteban, B.3    Granados, R.4    Green, A.R.5
  • 65
    • 0032962796 scopus 로고    scopus 로고
    • Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") administration
    • Colado MI, O'Shea E, Granados R, Esteban B, Martín AB, and Green AR (1999a) Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") administration. Br J Pharmacol 126:911-924.
    • (1999) Br J Pharmacol , vol.126 , pp. 911-924
    • Colado, M.I.1    O'Shea, E.2    Granados, R.3    Esteban, B.4    Martín, A.B.5    Green, A.R.6
  • 66
    • 0030980379 scopus 로고    scopus 로고
    • A study of the neurotoxic effect of MDMA ("ecstasy") on 5-HT neurons in the brains of mothers and neonates following administration of the drug during pregnancy
    • Colado MI, O'Shea E, Granados R, Misra A, Murray TK, and Green AR (1997b) A study of the neurotoxic effect of MDMA ("ecstasy") on 5-HT neurons in the brains of mothers and neonates following administration of the drug during pregnancy. Br J Pharmacol 121:827-833.
    • (1997) Br J Pharmacol , vol.121 , pp. 827-833
    • Colado, M.I.1    O'Shea, E.2    Granados, R.3    Misra, A.4    Murray, T.K.5    Green, A.R.6
  • 67
    • 0030986255 scopus 로고    scopus 로고
    • In vivo evidence for free radical involvement in 5-HT following administration of MDMA ("ecstasy") and p-chloroamphetamine but not the degeneration following fenfluramine
    • Colado MI, O'Shea E, Granados R, Murray TK, and Green AR (1997a) In vivo evidence for free radical involvement in 5-HT following administration of MDMA ("ecstasy") and p-chloroamphetamine but not the degeneration following fenfluramine. Br J Pharmacol 121:889-900.
    • (1997) Br J Pharmacol , vol.121 , pp. 889-900
    • Colado, M.I.1    O'Shea, E.2    Granados, R.3    Murray, T.K.4    Green, A.R.5
  • 68
    • 0029112473 scopus 로고
    • The hyperthermic and neurotoxic effects of "ecstasy" (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype
    • Colado MI, Williams JL, and Green AR (1995) The hyperthermic and neurotoxic effects of "Ecstasy" (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype. Br J Pharmacol 115:1281-1289.
    • (1995) Br J Pharmacol , vol.115 , pp. 1281-1289
    • Colado, M.I.1    Williams, J.L.2    Green, A.R.3
  • 69
    • 0023255308 scopus 로고
    • Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain
    • Commins DL, Vosmer G, Virus RM, Woolverton WL, Schuster CR, and Seiden LS (1987) Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain. J Pharmacol Exp Ther 241:338-345.
    • (1987) J Pharmacol Exp Ther , vol.241 , pp. 338-345
    • Commins, D.L.1    Vosmer, G.2    Virus, R.M.3    Woolverton, W.L.4    Schuster, C.R.5    Seiden, L.S.6
  • 70
    • 0031932040 scopus 로고    scopus 로고
    • Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat
    • Connor TJ, McNamara MG, Finn D, Currid A, O'Malley M, Redmond AM, Kelly JP, and Leonard BE (1998) Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat. Immunopharmacology 38:253-260.
    • (1998) Immunopharmacology , vol.38 , pp. 253-260
    • Connor, T.J.1    McNamara, M.G.2    Finn, D.3    Currid, A.4    O'Malley, M.5    Redmond, A.M.6    Kelly, J.P.7    Leonard, B.E.8
  • 71
    • 0033061982 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat
    • Connor TJ, McNamara MG, Kelly JP, and Leonard BE (1999) 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat. Hum Psychopharmacol 14:95-104.
    • (1999) Hum Psychopharmacol , vol.14 , pp. 95-104
    • Connor, T.J.1    McNamara, M.G.2    Kelly, J.P.3    Leonard, B.E.4
  • 72
    • 0015309522 scopus 로고
    • Hyperthermia and d-amphetamine toxicity in aggregated mice of different strains
    • Craig AL and Kupferberg HJ (1972) Hyperthermia and d-amphetamine toxicity in aggregated mice of different strains. J Pharmacol Exp Ther 180:616-624.
    • (1972) J Pharmacol Exp Ther , vol.180 , pp. 616-624
    • Craig, A.L.1    Kupferberg, H.J.2
  • 74
    • 0030796047 scopus 로고    scopus 로고
    • 2+-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylenedioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine
    • 2+-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylenedioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine. Br J Pharmacol 121:1735-1743.
    • (1997) Br J Pharmacol , vol.121 , pp. 1735-1743
    • Crespi, D.1    Mennini, T.2    Gobbi, M.3
  • 75
  • 76
    • 0030741356 scopus 로고    scopus 로고
    • Mood and cognitive effects of ±-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): Week-end "high" followed by midweek low
    • Curran HV and Travill RA (1997) Mood and cognitive effects of ±-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): week-end "high" followed by midweek low. Addiction 92:821-831.
    • (1997) Addiction , vol.92 , pp. 821-831
    • Curran, H.V.1    Travill, R.A.2
  • 77
    • 0028335838 scopus 로고
    • Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats
    • Dafters RI (1994) Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats. Psychopharmacology 114:505-508.
    • (1994) Psychopharmacology , vol.114 , pp. 505-508
    • Dafters, R.I.1
  • 78
    • 0028858685 scopus 로고
    • Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption and chronic dosing
    • Dafters RI (1995) Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption and chronic dosing. Physiol Behav 58: 877-882.
    • (1995) Physiol Behav , vol.58 , pp. 877-882
    • Dafters, R.I.1
  • 79
    • 0032778026 scopus 로고    scopus 로고
    • Level of use of 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) in humans correlates with EEG power and coherence
    • Dafters RI, Duffy F, O'Donnell PJ, and Bouquet C (1999) Level of use of 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) in humans correlates with EEG power and coherence. Psychopharmacology 145:82-90.
    • (1999) Psychopharmacology , vol.145 , pp. 82-90
    • Dafters, R.I.1    Duffy, F.2    O'Donnell, P.J.3    Bouquet, C.4
  • 80
    • 0031822039 scopus 로고    scopus 로고
    • Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") but not by fenfluramine
    • Dafters RI and Lynch E (1998) Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") but not by fenfluramine. Psychopharmacology 138:207-212.
    • (1998) Psychopharmacology , vol.138 , pp. 207-212
    • Dafters, R.I.1    Lynch, E.2
  • 81
    • 0036195642 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain
    • Darvesh AS, Shankaran M, and Gudelsky GA (2002) 3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain. J Pharmacol Exp Ther 300:138-144.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 138-144
    • Darvesh, A.S.1    Shankaran, M.2    Gudelsky, G.A.3
  • 82
    • 0030971740 scopus 로고    scopus 로고
    • Ecstasy (MDMA) in recreationa) users: Selfreported psychological and physiological effects
    • Davison D and Parrott AC (1997) Ecstasy (MDMA) in recreationa) users: selfreported psychological and physiological effects. Human Psychopharmacol 12: 221-226.
    • (1997) Human Psychopharmacol , vol.12 , pp. 221-226
    • Davison, D.1    Parrott, A.C.2
  • 85
    • 0031010421 scopus 로고    scopus 로고
    • An Appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat
    • De Souza I, Kelly JP, Harkin AJ, and Leonard BE (1997) An Appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat. Pharmacol Toxicol 80:207-210.
    • (1997) Pharmacol Toxicol , vol.80 , pp. 207-210
    • De Souza, I.1    Kelly, J.P.2    Harkin, A.J.3    Leonard, B.E.4
  • 86
    • 85047691384 scopus 로고
    • "Eve" and "ecstasy." A report of five deaths associated with the use of MDEA and MDMA
    • Dowling GP, McDonough ET III, and Bost RO (1987) "Eve" and "Ecstasy." A report of five deaths associated with the use of MDEA and MDMA. J Am Med Assoc 257:1615-1617.
    • (1987) J Am Med Assoc , vol.257 , pp. 1615-1617
    • Dowling, G.P.1    McDonough E.T. III2    Bost, R.O.3
  • 87
    • 0026080663 scopus 로고
    • 3,4-Methylenedioxymethamphetamine induces Fos-like proteins in rat basal ganglia: Reversal with MK 801
    • Dragunow M, Logan B, and Laverty R (1991) 3,4-Methylenedioxymethamphetamine induces Fos-like proteins in rat basal ganglia: reversal with MK 801. Eur J Pharmacol 206:255-258.
    • (1991) Eur J Pharmacol , vol.206 , pp. 255-258
    • Dragunow, M.1    Logan, B.2    Laverty, R.3
  • 88
    • 0033837504 scopus 로고    scopus 로고
    • Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice
    • Dulawa SC and Geyer MA (2000) Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice. Neuropharmacology 39:2170-2179.
    • (2000) Neuropharmacology , vol.39 , pp. 2170-2179
    • Dulawa, S.C.1    Geyer, M.A.2
  • 90
    • 0032694635 scopus 로고    scopus 로고
    • Acute injection of drugs with low addictive potential (delta(9)-tetrahydrocannabinol, 3,4-methylenedioxymethamphetamine, lysergic acid diamide) causes a much higher c-fos expression in limbic brain areas than highly addicting drugs (cocaine and morphine)
    • Erdtmann-Vourliotis M, Mayer P, Riechert U, and Hollt V (1999) Acute injection of drugs with low addictive potential (delta(9)-tetrahydrocannabinol, 3,4-methylenedioxymethamphetamine, lysergic acid diamide) causes a much higher c-fos expression in limbic brain areas than highly addicting drugs (cocaine and morphine). Mol Brain Res 71:313-324.
    • (1999) Mol Brain Res , vol.71 , pp. 313-324
    • Erdtmann-Vourliotis, M.1    Mayer, P.2    Riechert, U.3    Hollt, V.4
  • 91
    • 0035084704 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose
    • Esteban B, O'Shea E, Camarero J, Green AR, and Colado MI (2001) 3,4-methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose. Psychopharmacology 154:251-260.
    • (2001) Psychopharmacology , vol.154 , pp. 251-260
    • Esteban, B.1    O'Shea, E.2    Camarero, J.3    Green, A.R.4    Colado, M.I.5
  • 92
    • 0036011297 scopus 로고    scopus 로고
    • An antisense oligonucleotide targeted at MAO-B attenuates rat striatal serotonergic neurotoxicity induced by MDMA
    • Falk EM, Cook VJ, Nichols DE, and Sprague JE (2002) An antisense oligonucleotide targeted at MAO-B attenuates rat striatal serotonergic neurotoxicity induced by MDMA. Pharmacol Biochem Behav 72:617-622.
    • (2002) Pharmacol Biochem Behav , vol.72 , pp. 617-622
    • Falk, E.M.1    Cook, V.J.2    Nichols, D.E.3    Sprague, J.E.4
  • 93
    • 0032779463 scopus 로고    scopus 로고
    • Stereospecific analysis and enantiomeric disposition of 3,4-methylenedioxymethamphetamine (ecstasy) in humans
    • Fallon JK, Kicman AT, Henry JA, Milligan PJ, Cowan DA, and Hutt AJ (1999) Stereospecific analysis and enantiomeric disposition of 3,4-methylenedioxymethamphetamine (Ecstasy) in humans. Clin Chem 45:1058-1069.
    • (1999) Clin Chem , vol.45 , pp. 1058-1069
    • Fallon, J.K.1    Kicman, A.T.2    Henry, J.A.3    Milligan, P.J.4    Cowan, D.A.5    Hutt, A.J.6
  • 94
    • 0035987117 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: Serotonergic involvement
    • Fantegrossi WE, Ullrich T, Rice KC, Woods JH, and Winger G (2002) 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement. Psychopharmacology 161:356-364.
    • (2002) Psychopharmacology , vol.161 , pp. 356-364
    • Fantegrossi, W.E.1    Ullrich, T.2    Rice, K.C.3    Woods, J.H.4    Winger, G.5
  • 95
    • 0028833356 scopus 로고
    • Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX
    • Farfel GM and Seiden LS (1995) Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX. J Pharmacol Exp Ther 272:860-867.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 860-867
    • Farfel, G.M.1    Seiden, L.S.2
  • 97
    • 0029125154 scopus 로고
    • Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (±)-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Fischer C, Hatzidimitriou G, Wlos J, Katz J, and Ricaurte G (1995) Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (±)-3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). J Neurosci 15:5476-5485.
    • (1995) J Neurosci , vol.15 , pp. 5476-5485
    • Fischer, C.1    Hatzidimitriou, G.2    Wlos, J.3    Katz, J.4    Ricaurte, G.5
  • 98
    • 0025685321 scopus 로고
    • Stereoselective pharmacokinetics of 3,4-methylenedioxymethamphetamine
    • Fitzgerald RL, Blanke RV, and Poklis A (1990) Stereoselective pharmacokinetics of 3,4-methylenedioxymethamphetamine. Chirality 2:241-248.
    • (1990) Chirality , vol.2 , pp. 241-248
    • Fitzgerald, R.L.1    Blanke, R.V.2    Poklis, A.3
  • 99
    • 0025634097 scopus 로고
    • Effects of methylenedioxymethamphetamine on the release of monoamines from rat brain slices
    • Fitzgerald JL and Reid JJ (1990) Effects of methylenedioxymethamphetamine on the release of monoamines from rat brain slices. Eur J Pharmacol 191:217-220.
    • (1990) Eur J Pharmacol , vol.191 , pp. 217-220
    • Fitzgerald, J.L.1    Reid, J.J.2
  • 100
    • 0027410102 scopus 로고
    • Interactions of methylenedioxymethamphetamine with monoamine transmitter release mechanisms in rat brain slices
    • Fitzgerald JL and Reid JJ (1993) Interactions of methylenedioxymethamphetamine with monoamine transmitter release mechanisms in rat brain slices. Naunyn-Schmiedeberg's Arch Pharmacol 347:313-323.
    • (1993) Naunyn-Schmiedeberg's Arch Pharmacol , vol.347 , pp. 313-323
    • Fitzgerald, J.L.1    Reid, J.J.2
  • 101
    • 0028053883 scopus 로고
    • Sympathomimetic actions of methylenedioxymethamphetamine in rat and rabbit isolated cardiovascular tissues
    • Fitzgerald JL and Reid JJ (1994) Sympathomimetic actions of methylenedioxymethamphetamine in rat and rabbit isolated cardiovascular tissues. J Pharm Pharmacol 46:826-832.
    • (1994) J Pharm Pharmacol , vol.46 , pp. 826-832
    • Fitzgerald, J.L.1    Reid, J.J.2
  • 102
    • 0036170307 scopus 로고    scopus 로고
    • Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity
    • Fone KCF, Beckett SRG, Topham IA, Swettenham J, Ball M, and Maddocks L (2002) Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity. Psychopharmacology 159:437-444.
    • (2002) Psychopharmacology , vol.159 , pp. 437-444
    • Fone, K.C.F.1    Beckett, S.R.G.2    Topham, I.A.3    Swettenham, J.4    Ball, M.5    Maddocks, L.6
  • 103
    • 0034758097 scopus 로고    scopus 로고
    • Arginine vasopressin release in response to the administration of 3,4-methylenedioxymethamphetamine ("ecstasy"): Is metabolism a contributory factor?
    • Forsling M, Fallon JK, Kicman AT, Hutt AJ, Cowan AD, and Henry JA (2001) Arginine vasopressin release in response to the administration of 3,4-methylenedioxymethamphetamine ("ecstasy"): is metabolism a contributory factor? J Pharm Pharmacol 53:1357-1363.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 1357-1363
    • Forsling, M.1    Fallon, J.K.2    Kicman, A.T.3    Hutt, A.J.4    Cowan, A.D.5    Henry, J.A.6
  • 104
    • 0036183351 scopus 로고    scopus 로고
    • The effect of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus
    • Forsling ML, Fallon JK, Shah D, Tilbrook GS, Cowan DA, Kicman, AT, and Hutt AJ (2002) The effect of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus. Br J Pharmacol 135:649-656.
    • (2002) Br J Pharmacol , vol.135 , pp. 649-656
    • Forsling, M.L.1    Fallon, J.K.2    Shah, D.3    Tilbrook, G.S.4    Cowan, D.A.5    Kicman, A.T.6    Hutt, A.J.7
  • 105
    • 0036019553 scopus 로고    scopus 로고
    • Neuropsychological evidence of relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") poly-drug users
    • Fox HC, McLean A, Turner JJD, Parrott AC, Rogers R, and Sahakian BJ (2002) Neuropsychological evidence of relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") poly-drug users. Psychopharmacology 162:203-214.
    • (2002) Psychopharmacology , vol.162 , pp. 203-214
    • Fox, H.C.1    McLean, A.2    Turner, J.J.D.3    Parrott, A.C.4    Rogers, R.5    Sahakian, B.J.6
  • 106
    • 0035663512 scopus 로고    scopus 로고
    • Ecstasy use: Cognitive deficits related to dosage rather than self-reported problematic use of the drug
    • Fox HC, Parrott AC, and Turner JJD (2001) Ecstasy use: cognitive deficits related to dosage rather than self-reported problematic use of the drug. J Psychopharmacol 16:273-281.
    • (2001) J Psychopharmacol , vol.16 , pp. 273-281
    • Fox, H.C.1    Parrott, A.C.2    Turner, J.J.D.3
  • 107
    • 0031847128 scopus 로고    scopus 로고
    • Acute effects of dexfenfluramine (d-FEN) and methylenedioxymethamphetamine (MDMA) before and after short-course, high-dose treatment
    • Frederick DL, Ali SF, Gillam MP, Gossett J, Slikker W, and Paule MG (1998) Acute effects of dexfenfluramine (d-FEN) and methylenedioxymethamphetamine (MDMA) before and after short-course, high-dose treatment. Ann NY Acad Sci 44:183-190.
    • (1998) Ann NY Acad Sci , vol.44 , pp. 183-190
    • Frederick, D.L.1    Ali, S.F.2    Gillam, M.P.3    Gossett, J.4    Slikker, W.5    Paule, M.G.6
  • 108
    • 0028874867 scopus 로고
    • Behavioral and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatments in rhesus monkeys
    • Frederick DL, Ali SF, Slikker W Jr, Gilliam MP, Allen RR, and Paule MG (1995) Behavioral and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatments in rhesus monkeys. Neurotoxicol Teratol 17:531-541.
    • (1995) Neurotoxicol Teratol , vol.17 , pp. 531-541
    • Frederick, D.L.1    Ali, S.F.2    Slikker W., Jr.3    Gilliam, M.P.4    Allen, R.R.5    Paule, M.G.6
  • 109
    • 0031045838 scopus 로고    scopus 로고
    • Effects of MDMA on complex brain function in laboratory animals
    • Frederick DL and Paule MG (1997) Effects of MDMA on complex brain function in laboratory animals. Neurosci Biobehav Rev 21:67-78.
    • (1997) Neurosci Biobehav Rev , vol.21 , pp. 67-78
    • Frederick, D.L.1    Paule, M.G.2
  • 110
    • 0034761104 scopus 로고    scopus 로고
    • Localization of MDMA-induced brain activity in healthy volunteers using low resolution brain electromagnetic tomography (LORETA)
    • Frei E, Gamma A, Pascual-Marqui R, Lehmann D, Hell D, and Vollenweider FX (2001) Localization of MDMA-induced brain activity in healthy volunteers using low resolution brain electromagnetic tomography (LORETA). Hum Brain Mapp 14:152-165.
    • (2001) Hum Brain Mapp , vol.14 , pp. 152-165
    • Frei, E.1    Gamma, A.2    Pascual-Marqui, R.3    Lehmann, D.4    Hell, D.5    Vollenweider, F.X.6
  • 112
    • 0030432240 scopus 로고    scopus 로고
    • Effects of repeated administration of 3,4-methylenedioxymethamphetamine on 5-hydroxytryptamine neuronal activity and release in the rat brain in vivo
    • Gartside SE, McQuade R, and Sharp T (1996) Effects of repeated administration of 3,4-methylenedioxymethamphetamine on 5-hydroxytryptamine neuronal activity and release in the rat brain in vivo. J Pharmacol Exp Ther 279:277-283.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 277-283
    • Gartside, S.E.1    McQuade, R.2    Sharp, T.3
  • 115
    • 0029112937 scopus 로고
    • Detection of free radical formation during transient global ischemia and recirculation: Effects of intraischemic brain temperature modulation
    • Globus MY-T, Busto R, Lin B, Schnippering H, and Ginsberg MD (1995) Detection of free radical formation during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation. J Neurochem 65:1250-1256.
    • (1995) J Neurochem , vol.65 , pp. 1250-1256
    • Globus, M.Y.-T.1    Busto, R.2    Lin, B.3    Schnippering, H.4    Ginsberg, M.D.5
  • 116
    • 0024365005 scopus 로고
    • A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA
    • Gold LH, Hubner CB, and Koob GF (1989) A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA. Psychopharmacology 99:40-47.
    • (1989) Psychopharmacology , vol.99 , pp. 40-47
    • Gold, L.H.1    Hubner, C.B.2    Koob, G.F.3
  • 117
    • 0024160155 scopus 로고
    • Methysergide potentiates the hyperactivity produced by MDMA in rats
    • Gold LH and Koob GF (1988) Methysergide potentiates the hyperactivity produced by MDMA in rats. Pharmacol Biochem Behav 29:645-648.
    • (1988) Pharmacol Biochem Behav , vol.29 , pp. 645-648
    • Gold, L.H.1    Koob, G.F.2
  • 120
    • 0028199967 scopus 로고
    • Metabolic and thermoregulatory responses of the rat maintained in acrylic or wire-screen cages: Implications for pharmacological studies
    • Gordon CJ and Fogelson L (1994) Metabolic and thermoregulatory responses of the rat maintained in acrylic or wire-screen cages: implications for pharmacological studies. Physiol Behav 56:73-79.
    • (1994) Physiol Behav , vol.56 , pp. 73-79
    • Gordon, C.J.1    Fogelson, L.2
  • 121
    • 0026081849 scopus 로고
    • Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat
    • Gordon CJ, Watkinson WP, O'Callaghan JP, and Miller DB (1991) Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat. Pharmacol Biochem Behav 38:339-344.
    • (1991) Pharmacol Biochem Behav , vol.38 , pp. 339-344
    • Gordon, C.J.1    Watkinson, W.P.2    O'Callaghan, J.P.3    Miller, D.B.4
  • 122
    • 0025950754 scopus 로고
    • Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate
    • Gough B, Ali SF, Slikker W Jr, and Holson RR (1991) Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate. Pharmacol Biochem Behav 39:619-623.
    • (1991) Pharmacol Biochem Behav , vol.39 , pp. 619-623
    • Gough, B.1    Ali, S.F.2    Slikker W., Jr.3    Holson, R.R.4
  • 124
    • 0015075857 scopus 로고
    • Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan
    • Grahame-Smith DG (1971a) Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan. J Neurochem 18:1053-1066.
    • (1971) J Neurochem , vol.18 , pp. 1053-1066
    • Grahame-Smith, D.G.1
  • 125
    • 0015192083 scopus 로고
    • Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine inhibitor
    • Grahame-Smith DG (1971b) Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine inhibitor. Br J Pharmacol 43:854-864.
    • (1971) Br J Pharmacol , vol.43 , pp. 854-864
    • Grahame-Smith, D.G.1
  • 126
    • 0030831702 scopus 로고    scopus 로고
    • The effect of the repeated administration of the compound 3,4-methylenedioxymethamphetamine on the response of rats to the 5-HT2A, C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)
    • Granoff MI and Ashby CR (1998) The effect of the repeated administration of the compound 3,4-methylenedioxymethamphetamine on the response of rats to the 5-HT2A, C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI). Neuropsychobiology 37:36-40.
    • (1998) Neuropsychobiology , vol.37 , pp. 36-40
    • Granoff, M.I.1    Ashby, C.R.2
  • 127
    • 0035164413 scopus 로고    scopus 로고
    • Effect of the repeated administration of (+/-)-3,4-methylenedioxymethamphetamine on the behavioral response of rats to the 5-HT1A receptor agonist (+/-)-8-hydroxy-(di-n-propylamino)tetralin
    • Granoff MI and Ashby CR (2001) Effect of the repeated administration of (+/-)-3,4-methylenedioxymethamphetamine on the behavioral response of rats to the 5-HT1A receptor agonist (+/-)-8-hydroxy-(di-n-propylamino)tetralin. Neuropsychobiology 43:42-48.
    • (2001) Neuropsychobiology , vol.43 , pp. 42-48
    • Granoff, M.I.1    Ashby, C.R.2
  • 128
    • 0000418383 scopus 로고
    • Vasodilatation and body warming in the rat
    • Grant RT (1963) Vasodilatation and body warming in the rat. J Physiol (Lond) 167:311-317.
    • (1963) J Physiol (Lond) , vol.167 , pp. 311-317
    • Grant, R.T.1
  • 129
    • 0031593429 scopus 로고    scopus 로고
    • Clomethiazole (Zendra) in acute ischemic stroke: Basic pharmacology and biochemistry and clinical efficacy
    • Green AR (1998) Clomethiazo]e (Zendra) in acute ischemic stroke: basic pharmacology and biochemistry and clinical efficacy. Pharmacol Ther 80:123-147.
    • (1998) Pharmacol Ther , vol.80 , pp. 123-147
    • Green, A.R.1
  • 130
    • 0029067178 scopus 로고
    • Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy")
    • Green AR, Cross AJ, and Goodwin GM (1995) Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"). Psychopharmacology 119:247-260.
    • (1995) Psychopharmacology , vol.119 , pp. 247-260
    • Green, A.R.1    Cross, A.J.2    Goodwin, G.M.3
  • 131
    • 0029948929 scopus 로고    scopus 로고
    • Ecstasy and neurodegeneration
    • Green AR and Goodwin GM (1996) Ecstasy and neurodegeneration. Br Med J 312:1493.
    • (1996) Br Med J , vol.312 , pp. 1493
    • Green, A.R.1    Goodwin, G.M.2
  • 132
    • 0017290644 scopus 로고
    • Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine
    • Green AR and Grahame-Smith DG (1976) Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine. Nature (Lond) 260:487-491.
    • (1976) Nature (Lond) , vol.260 , pp. 487-491
    • Green, A.R.1    Grahame-Smith, D.G.2
  • 133
    • 0019456315 scopus 로고
    • A behavioural and biochemical study in rats of 5-hydroxytryptamine agonists and antagonists with observations on structure-activity requirements for the agonists
    • Green AR, Hall JE, and Rees AR (1981) A behavioural and biochemical study in rats of 5-hydroxytryptamine agonists and antagonists with observations on structure-activity requirements for the agonists. Br J Pharmacol 73:703-720.
    • (1981) Br J Pharmacol , vol.73 , pp. 703-720
    • Green, A.R.1    Hall, J.E.2    Rees, A.R.3
  • 134
    • 0017143191 scopus 로고
    • Evidence concerning the involvement of 5-hydroxytryptamine in the locomotor activity produced by amphetamine or tranylcypromine plus L-Dopa
    • Green AR and Kelly PH (1976) Evidence concerning the involvement of 5-hydroxytryptamine in the locomotor activity produced by amphetamine or tranylcypromine plus L-Dopa. Br J Pharmacol 57:141-147.
    • (1976) Br J Pharmacol , vol.57 , pp. 141-147
    • Green, A.R.1    Kelly, P.H.2
  • 135
    • 0036038315 scopus 로고    scopus 로고
    • On the anxiogenic and anxiolytic nature of long-term cerebral 5-HT depletion following MDMA
    • Green AR and McGregor IS (2002) On the anxiogenic and anxiolytic nature of long-term cerebral 5-HT depletion following MDMA. Psychopharmacology 164: 448-450.
    • (2002) Psychopharmacology , vol.164 , pp. 448-450
    • Green, A.R.1    McGregor, I.S.2
  • 137
    • 0028986825 scopus 로고
    • 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
    • Griebel G (1995) 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacol Ther 65:319-395.
    • (1995) Pharmacol Ther , vol.65 , pp. 319-395
    • Griebel, G.1
  • 138
    • 0022906545 scopus 로고
    • Can drugs be used to enhance the psychotherapeutic process?
    • Grinspoon L and Bakalar JB (1986) Can drugs be used to enhance the psychotherapeutic process? Am J Psychotherapy 40:393-404.
    • (1986) Am J Psychotherapy , vol.40 , pp. 393-404
    • Grinspoon, L.1    Bakalar, J.B.2
  • 139
    • 0030481579 scopus 로고    scopus 로고
    • Effect of ascorbate and cysteine on the 3,4-methylenedioxymethamphetamine-induced depletion of brain serotonin
    • Gudelsky GA (1996) Effect of ascorbate and cysteine on the 3,4-methylenedioxymethamphetamine-induced depletion of brain serotonin. J Neural Transm 102:1397-1404.
    • (1996) J Neural Transm , vol.102 , pp. 1397-1404
    • Gudelsky, G.A.1
  • 140
    • 0030070015 scopus 로고    scopus 로고
    • Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: Implications for serotonin-dopamine interactions
    • Gudelsky GA and Nash JF (1996) Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions. J Neurochem 66:243-249.
    • (1996) J Neurochem , vol.66 , pp. 243-249
    • Gudelsky, G.A.1    Nash, J.F.2
  • 141
    • 0028113293 scopus 로고
    • Potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists
    • Gudelsky GA, Yamamoto BK, and Nash JF (1994) Potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists. Eur J Pharmacol 264:325-330.
    • (1994) Eur J Pharmacol , vol.264 , pp. 325-330
    • Gudelsky, G.A.1    Yamamoto, B.K.2    Nash, J.F.3
  • 142
    • 0012644745 scopus 로고
    • The action of some amines related to adrenaline. Cyclohexylalkylamines
    • Gunn JA and Gurd MR (1940) The action of some amines related to adrenaline. Cyclohexylalkylamines. J Physiol (Lond) 97:453-470.
    • (1940) J Physiol (Lond) , vol.97 , pp. 453-470
    • Gunn, J.A.1    Gurd, M.R.2
  • 143
    • 0037141765 scopus 로고    scopus 로고
    • Increased anxiety in rats after 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): Association with serotonin depletion
    • Gurtman CG, Morley KC, Li KM, Hunt GE, and McGregor IS (2002) Increased anxiety in rats after 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): association with serotonin depletion. Eur J Pharmacol 446:89-96.
    • (2002) Eur J Pharmacol , vol.446 , pp. 89-96
    • Gurtman, C.G.1    Morley, K.C.2    Li, K.M.3    Hunt, G.E.4    McGregor, I.S.5
  • 144
    • 0030691910 scopus 로고    scopus 로고
    • Hydroxylation of salicylate and phenylalanine as assays for hydroxyl radicals: A cautionary note visited for the third time
    • Halliwell B and Kaur H (1997) Hydroxylation of salicylate and phenylalanine as assays for hydroxyl radicals: a cautionary note visited for the third time. Free Radic Res 27:239-244.
    • (1997) Free Radic Res , vol.27 , pp. 239-244
    • Halliwell, B.1    Kaur, H.2
  • 145
    • 0025733745 scopus 로고
    • Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary note
    • Halliwell B, Kaur H, and Ingelman-Sundberg M (1991) Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note. Free Radic Biol Med 10:439-441.
    • (1991) Free Radic Biol Med , vol.10 , pp. 439-441
    • Halliwell, B.1    Kaur, H.2    Ingelman-Sundberg, M.3
  • 146
    • 0036182254 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: Mechanisms and implications for toxicity
    • Hansen JP, Riddle EL, Sandoval V, Brown JM, Gibb JW, Hanson GR, and Fleckenstein AE (2002) Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for toxicity. J Pharmacol Exp Ther 300:1093-1100.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 1093-1100
    • Hansen, J.P.1    Riddle, E.L.2    Sandoval, V.3    Brown, J.M.4    Gibb, J.W.5    Hanson, G.R.6    Fleckenstein, A.E.7
  • 147
    • 0015859726 scopus 로고
    • Relationship of the structure of mescaline and seven analogs to toxicity and behaviour in five species of laboratory animals
    • Hardman HF, Haavik CO, and Seevers MH (1973) Relationship of the structure of mescaline and seven analogs to toxicity and behaviour in five species of laboratory animals. Toxicol Appl Pharmacol 25:299-309.
    • (1973) Toxicol Appl Pharmacol , vol.25 , pp. 299-309
    • Hardman, H.F.1    Haavik, C.O.2    Seevers, M.H.3
  • 148
    • 0035830531 scopus 로고    scopus 로고
    • Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats
    • Harkin A, Connor TJ, Mulrooney J, Kelly JP, and Leonard BE (2001) Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats. Life Sci 68:1367-1382.
    • (2001) Life Sci , vol.68 , pp. 1367-1382
    • Harkin, A.1    Connor, T.J.2    Mulrooney, J.3    Kelly, J.P.4    Leonard, B.E.5
  • 150
    • 0036453091 scopus 로고    scopus 로고
    • Long-term partial 5-HT depletion: Interference of anxiety and impulsivity?
    • Harro J (2002) Long-term partial 5-HT depletion: interference of anxiety and impulsivity? Psychopharmacology 164:433-434.
    • (2002) Psychopharmacology , vol.164 , pp. 433-434
    • Harro, J.1
  • 151
    • 0027177538 scopus 로고
    • Methylenedioxyamphetamine: Neurotoxic effects on serotonergic projections to brainstem nuclei in the rat
    • Harvey JA, McMaster SE, and Romano AG (1993) Methylenedioxyamphetamine: neurotoxic effects on serotonergic projections to brainstem nuclei in the rat. Brain Res 619:1-14.
    • (1993) Brain Res , vol.619 , pp. 1-14
    • Harvey, J.A.1    McMaster, S.E.2    Romano, A.G.3
  • 152
    • 0030849138 scopus 로고    scopus 로고
    • Induction of Fos protein by 3,4-methylenedioxymethamphetamine (ecstasy) in rat brain: Regional differences in pharmacological manipulation
    • Hashimoto K, Tomitaka S-H, Narita N, Minabe Y, and Iyo M (1997) Induction of Fos protein by 3,4-methylenedioxymethamphetamine (Ecstasy) in rat brain: regional differences in pharmacological manipulation. Addiction Biol 2:317-326.
    • (1997) Addiction Biol , vol.2 , pp. 317-326
    • Hashimoto, K.1    Tomitaka, S.-H.2    Narita, N.3    Minabe, Y.4    Iyo, M.5
  • 153
    • 0033564773 scopus 로고    scopus 로고
    • Altered serotonin innervation patterns in the forebrain of monkeys treated with (±)3,4-methylenedioxymethamphetamine seven years previously: Factors influencing abnormal recovery
    • Hatzidimitriou G, McCann UD, and Ricaurte GA (1999) Altered serotonin innervation patterns in the forebrain of monkeys treated with
    • (1999) J Neurosci , vol.19 , pp. 5096-5107
    • Hatzidimitriou, G.1    McCann, U.D.2    Ricaurte, G.A.3
  • 154
    • 0034933533 scopus 로고    scopus 로고
    • Subjective ratings of prospective memory deficits in MDMA ("ecstasy") users
    • Heffernan TM, Ling J, and Scholey AB (2001) Subjective ratings of prospective memory deficits in MDMA ("ecstasy") users. Hum Psychopharmacol Clin Exp 16:607-613.
    • (2001) Hum Psychopharmacol Clin Exp , vol.16 , pp. 607-613
    • Heffernan, T.M.1    Ling, J.2    Scholey, A.B.3
  • 155
    • 0032979515 scopus 로고    scopus 로고
    • 3,4-Methylenedioxy analogues of amphetamine: Defining the risks to humans
    • Hegadoren KM, Baker GB, and Bourin M (1999) 3,4-methylenedioxy analogues of amphetamine: defining the risks to humans. Neurosci Biobehav Rev 23:539-553.
    • (1999) Neurosci Biobehav Rev , vol.23 , pp. 539-553
    • Hegadoren, K.M.1    Baker, G.B.2    Bourin, M.3
  • 156
    • 0019450020 scopus 로고
    • Unexpected differences between mazindol and its homologs on biochemical and behavioral responses
    • Heikkila RE, Cabbat FS, Manzino L, Babington RG, and Houlihan WJ (1981) Unexpected differences between mazindol and its homologs on biochemical and behavioral responses. J Pharmacol Exp Ther 217:745-749.
    • (1981) J Pharmacol Exp Ther , vol.217 , pp. 745-749
    • Heikkila, R.E.1    Cabbat, F.S.2    Manzino, L.3    Babington, R.G.4    Houlihan, W.J.5
  • 157
    • 0024359103 scopus 로고
    • Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat
    • Hekmatpanah CR, McKenna DJ, and Peroutka SJ (1989) Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat. Neurosci Lett 104:178-182.
    • (1989) Neurosci Lett , vol.104 , pp. 178-182
    • Hekmatpanah, C.R.1    McKenna, D.J.2    Peroutka, S.J.3
  • 158
    • 0021323928 scopus 로고
    • Serotonergic function in depression. Prolactin responses to intravenous tryptophan in depressed patients and healthy subjects
    • Heninger GR, Charney DS, and Sternberg DE (1984) Serotonergic function in depression. Prolactin responses to intravenous tryptophan in depressed patients and healthy subjects. Arch Gen Psychiatry 41:398-402.
    • (1984) Arch Gen Psychiatry , vol.41 , pp. 398-402
    • Heninger, G.R.1    Charney, D.S.2    Sternberg, D.E.3
  • 159
    • 0026684873 scopus 로고
    • Ecstasy and the dance of death
    • Henry JA (1992) Ecstasy and the dance of death. Br Med J 305:5-6.
    • (1992) Br Med J , vol.305 , pp. 5-6
    • Henry, J.A.1
  • 160
    • 0026680529 scopus 로고
    • Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")
    • Henry JA, Jeffreys KJ, and Dawling S (1992) Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy"). Lancet 340:384-387.
    • (1992) Lancet , vol.340 , pp. 384-387
    • Henry, J.A.1    Jeffreys, K.J.2    Dawling, S.3
  • 161
    • 0028557961 scopus 로고
    • Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ("ecstasy") to rats
    • Hewitt KE and Green AR (1994) Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ("Ecstasy") to rats. Neuropharmacology 33:1589-1595.
    • (1994) Neuropharmacology , vol.33 , pp. 1589-1595
    • Hewitt, K.E.1    Green, A.R.2
  • 162
    • 0025121255 scopus 로고
    • Metabolism of methylenedioxymethamphetamine: Formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct
    • Hiramatsu M, Kumagai Y, Unger SE, and Cho AK (1990) Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct. J Pharmacol Exp Ther 254:521-527.
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 521-527
    • Hiramatsu, M.1    Kumagai, Y.2    Unger, S.E.3    Cho, A.K.4
  • 163
    • 0024366246 scopus 로고
    • The effect of optical isomers of 3,4-methylenedioxymethamphetamine (MDMA) on stereotyped behavior in rats
    • Hiramatsu M, Nabeshima T, Kameyama T, Maeda Y, and Cho AK (1989) The effect of optical isomers of 3,4-methylenedioxymethamphetamine (MDMA) on stereotyped behavior in rats. Pharmacol Biochem Behav 33:343-346.
    • (1989) Pharmacol Biochem Behav , vol.33 , pp. 343-346
    • Hiramatsu, M.1    Nabeshima, T.2    Kameyama, T.3    Maeda, Y.4    Cho, A.K.5
  • 164
    • 0023918895 scopus 로고
    • The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward
    • Hubner CB, Bird M, Rassnick S, and Kornetsky C (1988) The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward. Psychopharmacology 95: 49-51.
    • (1988) Psychopharmacology , vol.95 , pp. 49-51
    • Hubner, C.B.1    Bird, M.2    Rassnick, S.3    Kornetsky, C.4
  • 165
    • 0029042370 scopus 로고
    • Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system
    • Hughes P and Dragunow M (1995) Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev 47:133-178.
    • (1995) Pharmacol Rev , vol.47 , pp. 133-178
    • Hughes, P.1    Dragunow, M.2
  • 166
    • 0033971069 scopus 로고    scopus 로고
    • Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation
    • Imam SZ and Ali SF (2000) Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation. Brain Res 855:186-191.
    • (2000) Brain Res , vol.855 , pp. 186-191
    • Imam, S.Z.1    Ali, S.F.2
  • 167
    • 0033533081 scopus 로고    scopus 로고
    • Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: Protective effects of peroxynitrite decomposition catalyst
    • Imam SZ, Crow JP, Newport GD, Islam F, Slikker W Jr, and Ali SF (1999) Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst. Brain Res 837:15-21.
    • (1999) Brain Res , vol.837 , pp. 15-21
    • Imam, S.Z.1    Crow, J.P.2    Newport, G.D.3    Islam, F.4    Slikker W., Jr.5    Ali, S.F.6
  • 168
    • 0035155763 scopus 로고    scopus 로고
    • Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: Evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase
    • Imam SZ, Newport GD, Itzhak Y, Cadet JL, Islam F, Slikker W Jr and Ali SF (2001) Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase. J Neurochem 76:745-749.
    • (2001) J Neurochem , vol.76 , pp. 745-749
    • Imam, S.Z.1    Newport, G.D.2    Itzhak, Y.3    Cadet, J.L.4    Islam, F.5    Slikker W., Jr.6    Ali, S.F.7
  • 169
    • 0024383159 scopus 로고
    • 3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in Rhesus monkeys
    • Insel TR, Battaglia G, Johannessen JN, Marra S, and De Souza EB (1989) 3,4-methylenedioxymethamphetamine ("Ecstasy") selectively destroys brain serotonin terminals in Rhesus monkeys. J Pharmacol Exp Ther 249:713-720.
    • (1989) J Pharmacol Exp Ther , vol.249 , pp. 713-720
    • Insel, T.R.1    Battaglia, G.2    Johannessen, J.N.3    Marra, S.4    De Souza, E.B.5
  • 170
    • 0031594132 scopus 로고    scopus 로고
    • Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity
    • Itzhak Y, Gandia C, Huang PL, and Ali SF (1998) Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity. J Pharmacol Exp Ther 284:1040-1047.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 1040-1047
    • Itzhak, Y.1    Gandia, C.2    Huang, P.L.3    Ali, S.F.4
  • 171
    • 0034637885 scopus 로고    scopus 로고
    • nNOS inhibitors attenuate methamphetamine-induced dopaminergic neurotoxicity but not hyperthermia in mice
    • Itzhak Y, Martin JL, and Ali SF (2000) nNOS inhibitors attenuate methamphetamine-induced dopaminergic neurotoxicity but not hyperthermia in mice. Neuroreport 11:2943-2946.
    • (2000) Neuroreport , vol.11 , pp. 2943-2946
    • Itzhak, Y.1    Martin, J.L.2    Ali, S.F.3
  • 174
    • 0032903612 scopus 로고    scopus 로고
    • Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (ecstasy)
    • Jayanthi S, Ladenheim B, Andrews AM, and Cadet JL (1999) Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy). Neuroscience 91:1379-1387.
    • (1999) Neuroscience , vol.91 , pp. 1379-1387
    • Jayanthi, S.1    Ladenheim, B.2    Andrews, A.M.3    Cadet, J.L.4
  • 175
    • 0023838751 scopus 로고
    • Effects of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine isomers on central serotonergic, dopaminergic and nigral neurotensin systems of the rat
    • Johnson M, Letter AA, Merchant K, Hanson GR, and Gibb JW (1988) Effects of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine isomers on central serotonergic, dopaminergic and nigral neurotensin systems of the rat. J Pharmacol Exp Ther 244:977-982.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 977-982
    • Johnson, M.1    Letter, A.A.2    Merchant, K.3    Hanson, G.R.4    Gibb, J.W.5
  • 176
    • 0026764178 scopus 로고
    • Effect of flunarizine and nimodipine on the decrease in tryptophan hydroxylase activity induced by methamphetamine and 3,4-methylenedioxymethamphetamine
    • Johnson M, Mitros K, Stone DM, Zobrist R, Hanson GR, and Gibb JW (1992) Effect of flunarizine and nimodipine on the decrease in tryptophan hydroxylase activity induced by methamphetamine and 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 261:586-591.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 586-591
    • Johnson, M.1    Mitros, K.2    Stone, D.M.3    Zobrist, R.4    Hanson, G.R.5    Gibb, J.W.6
  • 177
    • 0037134207 scopus 로고    scopus 로고
    • Chronic treatment with supraphysiological levels of corticosterone enhances d-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse
    • Johnson EA, O'Callaghan JP, and Miller DB (2002b) Chronic treatment with supraphysiological levels of corticosterone enhances d-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse. Brain Res 933:130-138.
    • (2002) Brain Res , vol.933 , pp. 130-138
    • Johnson, E.A.1    O'Callaghan, J.P.2    Miller, D.B.3
  • 178
    • 0034284707 scopus 로고    scopus 로고
    • Restraint as a stressor in mice: Against the dopaminergic neurotoxicity of D-MDMA, low body weight mitigates restraint-induced hypothermia and consequent neuroprotection
    • Johnson EA, Sharp DS, and Miller DB (2000) Restraint as a stressor in mice: against the dopaminergic neurotoxicity of D-MDMA, low body weight mitigates restraint-induced hypothermia and consequent neuroprotection. Brain Res 875:107-118.
    • (2000) Brain Res , vol.875 , pp. 107-118
    • Johnson, E.A.1    Sharp, D.S.2    Miller, D.B.3
  • 180
    • 0032052721 scopus 로고    scopus 로고
    • The acute effects of amphetamine derivatives on extracellular serotonin and dopamine levels in rat nucleus accumbens
    • Kankaanpaa A, Meririnne E, Lillsunde P, and Seppala T (1998) The acute effects of amphetamine derivatives on extracellular serotonin and dopamine levels in rat nucleus accumbens. Pharmacol Biochem Behav 59:1003-1009.
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 1003-1009
    • Kankaanpaa, A.1    Meririnne, E.2    Lillsunde, P.3    Seppala, T.4
  • 182
    • 0026597505 scopus 로고
    • Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats
    • Kehne JH, McCloskey TC, Taylor VL, Black CK, Fadayel GM, and Schmidt CJ (1992) Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats. J Pharmacol Exp Ther 260:78-89.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 78-89
    • Kehne, J.H.1    McCloskey, T.C.2    Taylor, V.L.3    Black, C.K.4    Fadayel, G.M.5    Schmidt, C.J.6
  • 183
    • 0029940907 scopus 로고    scopus 로고
    • 5-HT modulation of auditory and visual sensorimotor gating: I. Effects of 5-HT releasers on sound and light prepulse inhibition in Wistar rats
    • Kehne JH, Padich RA, McCloskey TC, Taylor VL, and Schmidt CJ (1996b) 5-HT modulation of auditory and visual sensorimotor gating: I. Effects of 5-HT releasers on sound and light prepulse inhibition in Wistar rats. Psychopharmacology 124: 95-106.
    • (1996) Psychopharmacology , vol.124 , pp. 95-106
    • Kehne, J.H.1    Padich, R.A.2    McCloskey, T.C.3    Taylor, V.L.4    Schmidt, C.J.5
  • 184
    • 0036899022 scopus 로고    scopus 로고
    • Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain
    • Kelly PAT, Ritchie IM, Quate L, McBean DE, and Olverman HJ (2002) Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain. Br J Pharmacol 137:963-970.
    • (2002) Br J Pharmacol , vol.137 , pp. 963-970
    • Kelly, P.A.T.1    Ritchie, I.M.2    Quate, L.3    McBean, D.E.4    Olverman, H.J.5
  • 185
    • 0003110629 scopus 로고    scopus 로고
    • Brain temperature alters hydroxyl radical production during cerebral ischaemia/reperfusion in rats
    • Kil HY, Zhang J, and Piantadosi LA (1996) Brain temperature alters hydroxyl radical production during cerebral ischaemia/reperfusion in rats. J Cereb Blood Flow Metab 16:100-106.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 100-106
    • Kil, H.Y.1    Zhang, J.2    Piantadosi, L.A.3
  • 186
    • 0036123041 scopus 로고    scopus 로고
    • How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy?
    • Kish SJ (2002) How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy? Pharmacol Biochem Behav 71:845-855.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 845-855
    • Kish, S.J.1
  • 187
    • 0033868533 scopus 로고    scopus 로고
    • Striatal serotonin is depleted in brain of a human MDMA (ecstasy) user
    • Kish SJ, Furukawa Y, Ang L, Vorce SP, and Kalasinsky KS (2000) Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user. Neurology 55:294-296.
    • (2000) Neurology , vol.55 , pp. 294-296
    • Kish, S.J.1    Furukawa, Y.2    Ang, L.3    Vorce, S.P.4    Kalasinsky, K.S.5
  • 188
    • 0024347994 scopus 로고
    • Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys
    • Kleven MS, Woolverton WL, and Seiden LS (1989) Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys. Brain Res 488:121-125.
    • (1989) Brain Res , vol.488 , pp. 121-125
    • Kleven, M.S.1    Woolverton, W.L.2    Seiden, L.S.3
  • 189
    • 0030909052 scopus 로고    scopus 로고
    • MDMA induced dopamine release in vivo: Role of endogenous serotonin
    • Koch S and Galloway MP (1997) MDMA induced dopamine release in vivo: role of endogenous serotonin. J Neural Transm 104:135-146.
    • (1997) J Neural Transm , vol.104 , pp. 135-146
    • Koch, S.1    Galloway, M.P.2
  • 190
    • 0032553621 scopus 로고    scopus 로고
    • Nature of methamphetamine-induced rapid and reversible changes in dopamine transporters
    • Kokoshka JM, Vaughan RA, Hanson GR, and Fleckenstein AE (1998) Nature of methamphetamine-induced rapid and reversible changes in dopamine transporters. Eur J Pharmacol 361:269-275.
    • (1998) Eur J Pharmacol , vol.361 , pp. 269-275
    • Kokoshka, J.M.1    Vaughan, R.A.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 191
    • 0026707316 scopus 로고
    • Chronic 3,4-methylenedioxymethamphetamine (mdma) use - Effects on mood and neuropsychological function
    • Krystal JH, Price LH, Opsahl C, Ricaurte GA, and Heninger GR (1992) Chronic 3,4-methylenedioxymethamphetamine (mdma) use - effects on mood and neuropsychological function. Am J Drug Alcohol Abuse 18:331-341.
    • (1992) Am J Drug Alcohol Abuse , vol.18 , pp. 331-341
    • Krystal, J.H.1    Price, L.H.2    Opsahl, C.3    Ricaurte, G.A.4    Heninger, G.R.5
  • 192
    • 0028069445 scopus 로고
    • Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats
    • Kumagai Y, Lin LY, Hiratsuka A, Narimatsu S, Suzuki T, Yamada H, Oguri K, Yoshimura H, and Cho AK (1994) Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats. Mol Pharmacol 45.359-365.
    • (1994) Mol Pharmacol , vol.45 , pp. 359-365
    • Kumagai, Y.1    Lin, L.Y.2    Hiratsuka, A.3    Narimatsu, S.4    Suzuki, T.5    Yamada, H.6    Oguri, K.7    Yoshimura, H.8    Cho, A.K.9
  • 193
    • 0032585937 scopus 로고    scopus 로고
    • Investigation of the prejunctional alpha2-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens
    • Lavelle A, Honner V, and Docherty JR (1999) Investigation of the prejunctional alpha2-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens. Br J Pharmacol 128:975-980.
    • (1999) Br J Pharmacol , vol.128 , pp. 975-980
    • Lavelle, A.1    Honner, V.2    Docherty, J.R.3
  • 194
    • 0025367961 scopus 로고
    • Protection by MK 801 and other drugs of methylenedioxymethamphetamine (MDMA) neurotoxicity in rats and mice
    • Laverty R and Logan BJ (1990) Protection by MK 801 and other drugs of methylenedioxymethamphetamine (MDMA) neurotoxicity in rats and mice. Eur J Pharmacol 183:451-452.
    • (1990) Eur J Pharmacol , vol.183 , pp. 451-452
    • Laverty, R.1    Logan, B.J.2
  • 195
    • 0028104042 scopus 로고
    • MDMA (ecstasy) inhibition of MAO type A and type B: Comparisons with fenfluramine and fluoxetine (Prozac)
    • Leonardi ET and Azmitia EC (1994) MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac). Neuropsychopharmacology 10:231-238.
    • (1994) Neuropsychopharmacology , vol.10 , pp. 231-238
    • Leonardi, E.T.1    Azmitia, E.C.2
  • 196
    • 0030087725 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies
    • Lew R, Sabol KE, Chou C, Vosmer GL, Richards J, and Seiden LS (1996) Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: radioligand binding and autoradiography studies. J Pharmacol Exp Ther 276:855-865.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 855-865
    • Lew, R.1    Sabol, K.E.2    Chou, C.3    Vosmer, G.L.4    Richards, J.5    Seiden, L.S.6
  • 197
    • 0034061432 scopus 로고    scopus 로고
    • Acute psychological effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") are attenuated by the serotonin uptake inhibitor citalopram
    • Liechti ME, Baumann C, Gamma A, and Vollenweider FX (2000a) Acute psychological effects of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") are attenuated by the serotonin uptake inhibitor citalopram. Neuropsychopharmacology 22:513-521.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 513-521
    • Liechti, M.E.1    Baumann, C.2    Gamma, A.3    Vollenweider, F.X.4
  • 198
    • 0035130579 scopus 로고    scopus 로고
    • Effects of MDMA (Ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin
    • Liechti ME, Geyer MA, Hell D, and Vollenweider FX (2001) Effects of MDMA (Ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin. Neuropsychopharmacology 24:240-252.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 240-252
    • Liechti, M.E.1    Geyer, M.A.2    Hell, D.3    Vollenweider, F.X.4
  • 200
    • 0033738703 scopus 로고    scopus 로고
    • The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3,4-methylenedioxymethamphetamine ("ecstasy") in healthy volunteers
    • Liechti ME and Vollenweider FX (2000a) The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3,4-methylenedioxymethamphetamine ("Ecstasy") in healthy volunteers. J Psychopharmacol 14:269-274.
    • (2000) J Psychopharmacol , vol.14 , pp. 269-274
    • Liechti, M.E.1    Vollenweider, F.X.2
  • 201
    • 0034122139 scopus 로고    scopus 로고
    • Acute psychological and physiological effects of MDMA ("ecstasy") after haloperidol pretreatment in healthy humans
    • Liechti ME and Vollenweider FX (2000b) Acute psychological and physiological effects of MDMA ("Ecstasy") after haloperidol pretreatment in healthy humans. Eur Neuropsychopharmacol 10:289-295.
    • (2000) Eur Neuropsychopharmacol , vol.10 , pp. 289-295
    • Liechti, M.E.1    Vollenweider, F.X.2
  • 202
    • 0035674880 scopus 로고    scopus 로고
    • Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies
    • Liechti ME and Vollenweider FX (2001) Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies. Human Psychopharmacol 16:589-598.
    • (2001) Human Psychopharmacol , vol.16 , pp. 589-598
    • Liechti, M.E.1    Vollenweider, F.X.2
  • 203
    • 0024214871 scopus 로고
    • In vivo and in vitro metabolism of 3,4-(methylenedioxy)methamphetamine in the rat: Identification of metabolites using an ion trap detector
    • Lim HK and Foltz RL (1988) In vivo and in vitro metabolism of 3,4-(methylenedioxy)methamphetamine in the rat: identification of metabolites using an ion trap detector. Chem Res Toxicol 1:370-378.
    • (1988) Chem Res Toxicol , vol.1 , pp. 370-378
    • Lim, H.K.1    Foltz, R.L.2
  • 204
    • 0026262192 scopus 로고
    • In vivo formation of aromatic hydroxylated metabolites of 3,4-(methylenedioxy)methamphetamine in the rat: Identification by ion trap tandem mass spectrometric (MS/MS and MS/MS/MS) techniques
    • Lim HK and Foltz RL (1991a) In vivo formation of aromatic hydroxylated metabolites of 3,4-(methylenedioxy)methamphetamine in the rat: identification by ion trap tandem mass spectrometric (MS/MS and MS/MS/MS) techniques. Biol Mass Spectrom 20:677-686.
    • (1991) Biol Mass Spectrom , vol.20 , pp. 677-686
    • Lim, H.K.1    Foltz, R.L.2
  • 205
    • 0025747988 scopus 로고
    • Ion trap tandem mass spectrometric evidence for the metabolism of 3,4-(methylenedioxy)methamphetamine to the potent neurotoxins 2,4,5-trihydroxymethamphetamine and 2,4,5-trihydroxyamphetamine
    • Lim HK and Foltz RL (1991b) Ion trap tandem mass spectrometric evidence for the metabolism of 3,4-(methylenedioxy)methamphetamine to the potent neurotoxins 2,4,5-trihydroxymethamphetamine and 2,4,5-trihydroxyamphetamine. Chem Res Toxicol 4:626-632.
    • (1991) Chem Res Toxicol , vol.4 , pp. 626-632
    • Lim, H.K.1    Foltz, R.L.2
  • 206
    • 0033012662 scopus 로고    scopus 로고
    • The anxiogenic-like and anxiolytic-like effects of MDMA on mice in the elevated plus-maze: A comparison with amphetamine
    • Lin HQ, Burden PM, Christie MJ, and Johnston GAR (1999) The anxiogenic-like and anxiolytic-like effects of MDMA on mice in the elevated plus-maze: a comparison with amphetamine. Pharmacol Biochem Behav 62:403-408.
    • (1999) Pharmacol Biochem Behav , vol.62 , pp. 403-408
    • Lin, H.Q.1    Burden, P.M.2    Christie, M.J.3    Johnston, G.A.R.4
  • 207
    • 0031016242 scopus 로고    scopus 로고
    • Serotonergic modulation of 3,4-methylenedioxymethamphetamine (MDMA)-elicited reduction of response rate but not rewarding threshold in accumbal self-stimulation
    • Lin HQ, Jackson DM, Atrens DM, Christie MJ, and McGregor IS (1997) Serotonergic modulation of 3,4-methylenedioxymethamphetamine (MDMA)-elicited reduction of response rate but not rewarding threshold in accumbal self-stimulation. Brain Res 744:351-357.
    • (1997) Brain Res , vol.744 , pp. 351-357
    • Lin, H.Q.1    Jackson, D.M.2    Atrens, D.M.3    Christie, M.J.4    McGregor, I.S.5
  • 208
    • 0026731379 scopus 로고
    • Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes
    • Lin LY, Kumagai Y, and Cho AK (1992) Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes. Chem Res Toxicol 5:401-406.
    • (1992) Chem Res Toxicol , vol.5 , pp. 401-406
    • Lin, L.Y.1    Kumagai, Y.2    Cho, A.K.3
  • 209
    • 0023722481 scopus 로고
    • Differences between rats and mice in MDMA (methylenedioxymethamphetamine) neurotoxicity
    • Logan BJ, Laverty R, Sanderson WD, and Yee YB (1988) Differences between rats and mice in MDMA (methylenedioxymethamphetamine) neurotoxicity. Eur J Pharmacol 152:227-234.
    • (1988) Eur J Pharmacol , vol.152 , pp. 227-234
    • Logan, B.J.1    Laverty, R.2    Sanderson, W.D.3    Yee, Y.B.4
  • 210
    • 0023165026 scopus 로고
    • 3H-DOB (4-bromo-2,5 dimethoxyphenylisopropylamine) labels a guanyl nucleotide-sensitive state of cortical 5-HT2 receptors
    • Lyon RA, Davis KH, and Titeler M (1987) 3H-DOB (4-bromo-2,5 dimethoxyphenylisopropylamine) labels a guanyl nucleotide-sensitive state of cortical 5-HT2 receptors. Mol Pharmacol 31:194-199.
    • (1987) Mol Pharmacol , vol.31 , pp. 194-199
    • Lyon, R.A.1    Davis, K.H.2    Titeler, M.3
  • 211
    • 0030438476 scopus 로고    scopus 로고
    • Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat
    • Malberg JE, Sabol KE, and Seiden LS (1996) Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat. J Pharmacol Exp Ther 278:258-267.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 258-267
    • Malberg, J.E.1    Sabol, K.E.2    Seiden, L.S.3
  • 212
    • 0032125256 scopus 로고    scopus 로고
    • Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat
    • Malberg JE and Seiden LS (1998) Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J Neurosci 18:5086-5094.
    • (1998) J Neurosci , vol.18 , pp. 5086-5094
    • Malberg, J.E.1    Seiden, L.S.2
  • 213
    • 0034929871 scopus 로고    scopus 로고
    • MDMA ("ecstasy") exhibits an anxiogenic-like activity in social encounters between male mice
    • Maldonado E and Navarro JF (2001) MDMA ("ecstasy") exhibits an anxiogenic-like activity in social encounters between male mice. Pharmacol Res 44:27-31.
    • (2001) Pharmacol Res , vol.44 , pp. 27-31
    • Maldonado, E.1    Navarro, J.F.2
  • 214
    • 0032859960 scopus 로고    scopus 로고
    • Acute toxicity of 3,4-methylenedioxymethamphetamine (MDMA) in Sprague-Dawley and Dark Agouti rats
    • Malpass A, White JM, Irvine RJ, Somogyi AA, and Bochner F (1999) Acute toxicity of 3,4-methylenedioxymethamphetamine (MDMA) in Sprague-Dawley and Dark Agouti rats. Pharmacol Biochem Behav 64:29-34.
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 29-34
    • Malpass, A.1    White, J.M.2    Irvine, R.J.3    Somogyi, A.A.4    Bochner, F.5
  • 215
    • 0026342819 scopus 로고
    • Dual serotoninergic projections to forebrain in the rat: Morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives
    • Mamounas LA, Mullen CA, O'Hearn E, and Molliver ME (1991) Dual serotoninergic projections to forebrain in the rat: morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives. J Comp Neurol 314:558-586.
    • (1991) J Comp Neurol , vol.314 , pp. 558-586
    • Mamounas, L.A.1    Mullen, C.A.2    O'Hearn, E.3    Molliver, M.E.4
  • 216
    • 0024412579 scopus 로고
    • Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat
    • Mansbach RS, Braff DL, and Geyer MA (1989) Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat. Eur J Pharmacol 167:49-55.
    • (1989) Eur J Pharmacol , vol.167 , pp. 49-55
    • Mansbach, R.S.1    Braff, D.L.2    Geyer, M.A.3
  • 217
    • 0025354029 scopus 로고
    • The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat
    • Marek GJ, Vosmer G, and Seiden LS (1990) The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat. Brain Res 516:1-7.
    • (1990) Brain Res , vol.516 , pp. 1-7
    • Marek, G.J.1    Vosmer, G.2    Seiden, L.S.3
  • 220
    • 0031104882 scopus 로고    scopus 로고
    • Characterization of the disruptions of prepulse inhibition and habituation of startle induced by α-ethyltryptamine
    • Martinez DL and Geyer MA (1997) Characterization of the disruptions of prepulse inhibition and habituation of startle induced by α-ethyltryptamine. Neuropsychopharmacology 16:246-255.
    • (1997) Neuropsychopharmacology , vol.16 , pp. 246-255
    • Martinez, D.L.1    Geyer, M.A.2
  • 221
    • 0032968382 scopus 로고    scopus 로고
    • Cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine in humans
    • Mas M, Farré M, de la Torre R, Roset PN, Ortuño J, Segura J, and Camí J (1999) Cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine in humans. J Pharmacol Exp Ther 290:136-145.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 136-145
    • Mas, M.1    Farré, M.2    De la Torre, R.3    Roset, P.N.4    Ortuño, J.5    Segura, J.6    Camí, J.7
  • 222
    • 0034653801 scopus 로고    scopus 로고
    • Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ("ecstasy")
    • Maurer HH, Bickeboeller-Friedrich J, Kraemer T, and Peters FT (2000) Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ("Ecstasy"). Toxicol Lett (Shannon) 112-113:133-142.
    • (2000) Toxicol Lett (Shannon) , vol.112-113 , pp. 133-142
    • Maurer, H.H.1    Bickeboeller-Friedrich, J.2    Kraemer, T.3    Peters, F.T.4
  • 223
    • 0035800539 scopus 로고    scopus 로고
    • Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats
    • Mayerhofer A, Kovar K, and Schmidt WJ (2001) Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats. Neurosci Lett 308:99-102.
    • (2001) Neurosci Lett , vol.308 , pp. 99-102
    • Mayerhofer, A.1    Kovar, K.2    Schmidt, W.J.3
  • 225
    • 0033989637 scopus 로고    scopus 로고
    • Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users
    • McCann UD, Eligulashvili V, Mertl M, Murphy DL, and Ricaurte GA (1999a) Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users. Psychopharmacology 147:56-65.
    • (1999) Psychopharmacology , vol.147 , pp. 56-65
    • McCann, U.D.1    Eligulashvili, V.2    Mertl, M.3    Murphy, D.L.4    Ricaurte, G.A.5
  • 226
    • 0032587879 scopus 로고    scopus 로고
    • Cognitive performance in (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users: A controlled study
    • McCann UD, Mertl M, Eligulashvili V, and Ricaurte GA (1999b) Cognitive performance in (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users: a controlled study. Psychopharmacology 143:417-425.
    • (1999) Psychopharmacology , vol.143 , pp. 417-425
    • McCann, U.D.1    Mertl, M.2    Eligulashvili, V.3    Ricaurte, G.A.4
  • 227
    • 0025863667 scopus 로고
    • Lasting neuropsychiatric sequelae of (±)methylenedioxymethamphetamine ("ecstasy") in recreational users
    • McCann UD and Ricaurte GA (1991) Lasting neuropsychiatric sequelae of (±)methylenedioxymethamphetamine ("Ecstasy") in recreational users. J Clin Psychopharmacol 11:302-305.
    • (1991) J Clin Psychopharmacol , vol.11 , pp. 302-305
    • McCann, U.D.1    Ricaurte, G.A.2
  • 228
    • 0027008253 scopus 로고
    • MDMA ("ecstasy") and panic disorder: Induction by a single dose
    • McCann UD and Ricaurte GA (1992) MDMA ("Ecstasy") and panic disorder: induction by a single dose. Biol Psychiatry 32:950-953.
    • (1992) Biol Psychiatry , vol.32 , pp. 950-953
    • McCann, U.D.1    Ricaurte, G.A.2
  • 229
    • 0027230237 scopus 로고
    • Reinforcing subjective effects of (+/-)-3, 4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: Clinical evidence
    • McCann UD and Ricaurte GA (1993) Reinforcing subjective effects of (+/-)-3,4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: clinical evidence. J Clin Psychopharmacol 13:214-217.
    • (1993) J Clin Psychopharmacol , vol.13 , pp. 214-217
    • McCann, U.D.1    Ricaurte, G.A.2
  • 231
    • 0028176910 scopus 로고
    • Serotonin neurotoxiicity after (±)3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"): A controlled study in humans
    • McCann UD, Ridenour A, Shaham Y, and Ricaurte GA (1994) Serotonin neurotoxiicity after (±)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans. Neuropsychopharmacology 10:129-138.
    • (1994) Neuropsychopharmacology , vol.10 , pp. 129-138
    • McCann, U.D.1    Ridenour, A.2    Shaham, Y.3    Ricaurte, G.A.4
  • 232
    • 0029846728 scopus 로고    scopus 로고
    • Adverse reactions with 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy")
    • McCann UD, Slate SO, and Ricaurte GA (1996) Adverse reactions with 3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"). Drug Safety 15:107-115.
    • (1996) Drug Safety , vol.15 , pp. 107-115
    • McCann, U.D.1    Slate, S.O.2    Ricaurte, G.A.3
  • 233
    • 0032585201 scopus 로고    scopus 로고
    • Positron emission tomographic evidence of toxic effect of MDMA ("ecstasy") on brain serotonin neurons in human beings
    • McCann UD, Szabo Z, Scheffel U, Dannals RF, and Ricaurte GA (1998) Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings. Lancet 352:1433-1437.
    • (1998) Lancet , vol.352 , pp. 1433-1437
    • McCann, U.D.1    Szabo, Z.2    Scheffel, U.3    Dannals, R.F.4    Ricaurte, G.A.5
  • 235
    • 0034762682 scopus 로고    scopus 로고
    • Vascular actions of MDMA involve alphal and alpha2-adrenoceptors in the anaesthetized rat
    • McDaid J and Docherty JR (2001) Vascular actions of MDMA involve alphal and alpha2-adrenoceptors in the anaesthetized rat. Br J Pharmacol 139:429-437.
    • (2001) Br J Pharmacol , vol.139 , pp. 429-437
    • McDaid, J.1    Docherty, J.R.2
  • 236
    • 0034654246 scopus 로고    scopus 로고
    • Long term psychiatric and cognitive effects of MDMA use
    • McGuire P (2000) Long term psychiatric and cognitive effects of MDMA use. Toxicol Lett (Shannon) 112-113:153-156.
    • (2000) Toxicol Lett (Shannon) , vol.112-113 , pp. 153-156
    • McGuire, P.1
  • 237
    • 0028106251 scopus 로고
    • Diversity of psychopathology associated with use of 3,4-methylenedioxymethamphetamine ("ecstasy")
    • McGuire PK, Cope H, and Fahy TA (1994) Diversity of psychopathology associated with use of 3,4-methylenedioxymethamphetamine ("Ecstasy"). Br J Psychiatry 165:391-395.
    • (1994) Br J Psychiatry , vol.165 , pp. 391-395
    • McGuire, P.K.1    Cope, H.2    Fahy, T.A.3
  • 238
    • 0026073632 scopus 로고
    • Chronic paranoid psychosis after misuse of MDMA ("ecstasy")
    • McGuire P and Fahy T (1991) Chronic paranoid psychosis after misuse of MDMA ("ecstasy"). Br Med J 302:697.
    • (1991) Br Med J , vol.302 , pp. 697
    • McGuire, P.1    Fahy, T.2
  • 239
    • 0027366614 scopus 로고
    • Psychiatric symptoms in cannabis users
    • McGuire P, Jones P, and Murray R (1993) Psychiatric symptoms in cannabis users. Br J Psychiatry 163:698.
    • (1993) Br J Psychiatry , vol.163 , pp. 698
    • McGuire, P.1    Jones, P.2    Murray, R.3
  • 240
    • 0025014763 scopus 로고
    • Neurochemistry and neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy")
    • McKenna DJ and Peroutka SJ (1990) Neurochemistry and neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"). J Neurochem 54:14-22.
    • (1990) J Neurochem , vol.54 , pp. 14-22
    • McKenna, D.J.1    Peroutka, S.J.2
  • 241
    • 0029142917 scopus 로고
    • Some behavioural and neurochemical aspects of subacute (±)3,4-methylenedioxymethamphetamine administration in rats
    • McNamara MG, Kelly JP, and Leonard BE (1995) Some behavioural and neurochemical aspects of subacute (±)3,4-methylenedioxymethamphetamine administration in rats. Pharmacol Biochem Behav 52:479-484.
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 479-484
    • McNamara, M.G.1    Kelly, J.P.2    Leonard, B.E.3
  • 242
    • 0036152649 scopus 로고    scopus 로고
    • The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA "ecstasy") to rats
    • Mechan AO, Esteban B, O'Shea E, Elliott JM, Colado MI, and Green AR (2002a) The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA "ecstasy") to rats. Br J Pharmacol 135:170-180.
    • (2002) Br J Pharmacol , vol.135 , pp. 170-180
    • Mechan, A.O.1    Esteban, B.2    O'Shea, E.3    Elliott, J.M.4    Colado, M.I.5    Green, A.R.6
  • 243
    • 0036166759 scopus 로고    scopus 로고
    • A study of the effect of a single neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA: "Ecstasy") on the subsequent long-term behaviour of rats in the plus maze and open field
    • Mechan AO, Moran PM, Elliott JM, Young AMJ, Joseph MH, and Green AR (2002b) A study of the effect of a single neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA: "ecstasy") on the subsequent long-term behaviour of rats in the plus maze and open field. Psychopharmacology 159:167-175.
    • (2002) Psychopharmacology , vol.159 , pp. 167-175
    • Mechan, A.O.1    Moran, P.M.2    Elliott, J.M.3    Young, A.M.J.4    Joseph, M.H.5    Green, A.R.6
  • 244
    • 0036166805 scopus 로고    scopus 로고
    • A comparison between Dark Agouti and Sprague-Dawley rats in their behaviour on the elevated plus-maze, open-field apparatus and activity meters and their response to diazepam
    • Mechan AO, Moran PM, Elliott JM, Young AMJ, Joseph MH, and Green AR (2002c) A comparison between Dark Agouti and Sprague-Dawley rats in their behaviour on the elevated plus-maze, open-field apparatus and activity meters and their response to diazepam. Psychopharmacology 159:188-195.
    • (2002) Psychopharmacology , vol.159 , pp. 188-195
    • Mechan, A.O.1    Moran, P.M.2    Elliott, J.M.3    Young, A.M.J.4    Joseph, M.H.5    Green, A.R.6
  • 245
    • 0035010140 scopus 로고    scopus 로고
    • A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation
    • Mechan AO, O'Shea E, Elliott JM, Colado MI, and Green AR (2001) A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation. Psychopharmacology 155:413-418.
    • (2001) Psychopharmacology , vol.155 , pp. 413-418
    • Mechan, A.O.1    O'Shea, E.2    Elliott, J.M.3    Colado, M.I.4    Green, A.R.5
  • 246
    • 0028856757 scopus 로고
    • Pindolol pretreatment blocks stimulation by metachlorophenylpiperazine of prolactin but not cortisol secretion in normal men
    • Meltzer HY and Maes M (1995a) Pindolol pretreatment blocks stimulation by metachlorophenylpiperazine of prolactin but not cortisol secretion in normal men. Psychiatry Res 58:89-98.
    • (1995) Psychiatry Res , vol.58 , pp. 89-98
    • Meltzer, H.Y.1    Maes, M.2
  • 247
    • 0029075949 scopus 로고
    • Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men
    • Meltzer HY and Maes M (1995b) Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men. Biol Psychiatry 38:310-318.
    • (1995) Biol Psychiatry , vol.38 , pp. 310-318
    • Meltzer, H.Y.1    Maes, M.2
  • 248
    • 0028997389 scopus 로고
    • Metabolism of 5-(glutathion-S-yl)-α-methyldopamine following intracerebroventricular administration to male Sprague-Dawley rats
    • Miller RT, Lau SS, and Monks TJ (1995) Metabolism of 5-(glutathion-S-yl)-α-methyldopamine following intracerebroventricular administration to male Sprague-Dawley rats. Chem Res Toxicol 8:634-641.
    • (1995) Chem Res Toxicol , vol.8 , pp. 634-641
    • Miller, R.T.1    Lau, S.S.2    Monks, T.J.3
  • 249
    • 0029884986 scopus 로고    scopus 로고
    • Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-α-methyldopamine on brain dopamine, serotonin and norepinephrine concentrations in male Sprague-Dawley rats
    • Miller RT, Lau SS, and Monks TJ (1996) Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-α-methyldopamine on brain dopamine, serotonin and norepinephrine concentrations in male Sprague-Dawley rats. Chem Res Toxicol 9:457-465.
    • (1996) Chem Res Toxicol , vol.9 , pp. 457-465
    • Miller, R.T.1    Lau, S.S.2    Monks, T.J.3
  • 250
    • 0030951385 scopus 로고    scopus 로고
    • 2, 5-bis-(glutathion-S-yl)-α-methyldopamine, a putative metabolite of (±)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations
    • Miller RT, Lau SS, and Monks TJ (1997) 2, 5-bis-(glutathion-S-yl)-α-methyldopamine, a putative metabolite of (±)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations. Eur J Pharmacol 323:173-180.
    • (1997) Eur J Pharmacol , vol.323 , pp. 173-180
    • Miller, R.T.1    Lau, S.S.2    Monks, T.J.3
  • 251
    • 0027964301 scopus 로고
    • Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse
    • Miller DB and O'Callaghan JP (1994) Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. J Pharmacol Exp Ther 270:752-760.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 752-760
    • Miller, D.B.1    O'Callaghan, J.P.2
  • 252
    • 0029348577 scopus 로고
    • The role of temperature, stress and other factors in the neurotoxicity of the substituted amphetamines 3,4-methylenedioxymethamphetamine and fenfluramine
    • Miller DB and O'Callaghan JP (1995) The role of temperature, stress and other factors in the neurotoxicity of the substituted amphetamines 3,4-methylenedioxymethamphetamine and fenfluramine. Mol Neurobiol 11:177-192.
    • (1995) Mol Neurobiol , vol.11 , pp. 177-192
    • Miller, D.B.1    O'Callaghan, J.P.2
  • 253
    • 0030040183 scopus 로고    scopus 로고
    • Pathology of deaths associated with ecstasy and "Eve" misuse
    • Milroy CM, Clark JC, and Forrest ARW (1996) Pathology of deaths associated with ecstasy and "Eve" misuse. J Clin Pathol (London) 49:149-153.
    • (1996) J Clin Pathol (London) , vol.49 , pp. 149-153
    • Milroy, C.M.1    Clark, J.C.2    Forrest, A.R.W.3
  • 254
    • 0012833644 scopus 로고
    • The hypothalamus and the pharmacology of thermoregulation
    • (Cox B, Morris ID, and Weston AH eds) The Macmillan Press Ltd., London
    • Milton AS (1977) The hypothalamus and the pharmacology of thermoregulation, in Pharmacology of the Hypothalamus (Cox B, Morris ID, and Weston AH eds) The Macmillan Press Ltd., London.
    • (1977) Pharmacology of the Hypothalamus
    • Milton, A.S.1
  • 255
    • 0030929625 scopus 로고    scopus 로고
    • The interaction between the central and peripheral nervous systems in mediating the thermic effect of methamphetamine
    • Mohaghegh RA, Soulsby ME, Skinner RD, and Kennedy RH (1997) The interaction between the central and peripheral nervous systems in mediating the thermic effect of methamphetamine. Ann NY Acad Sci 813:197-203.
    • (1997) Ann NY Acad Sci , vol.813 , pp. 197-203
    • Mohaghegh, R.A.1    Soulsby, M.E.2    Skinner, R.D.3    Kennedy, R.H.4
  • 257
    • 0001314197 scopus 로고
    • Direct intracerebral administration of MDMA and MDA does not produce serotonin neurotoxicity
    • Molliver ME, O'Hearn E, Battaglia G, and De Souza ER (1986) Direct intracerebral administration of MDMA and MDA does not produce serotonin neurotoxicity. Soc Neurosci Abstr 12:1234.
    • (1986) Soc Neurosci Abstr , vol.12 , pp. 1234
    • Molliver, M.E.1    O'Hearn, E.2    Battaglia, G.3    De Souza, E.R.4
  • 258
    • 0029670493 scopus 로고    scopus 로고
    • P-chloroamphetamine induces c-fos in rat brain: A study of serotonin2A/ 2C receptor function
    • Moorman JM and Leslie RA (1996) P-chloroamphetamine induces c-fos in rat brain: a study of serotonin2A/2C receptor function. Neuroscience 72:129-139.
    • (1996) Neuroscience , vol.72 , pp. 129-139
    • Moorman, J.M.1    Leslie, R.A.2
  • 259
    • 0002209037 scopus 로고
    • The use of interspecies scaling in toxicokinetics
    • (Yacogi A, Kelly J, and Batra V eds), Pergamon Press, New York
    • Mordenti J and Chappell W (1989) The use of interspecies scaling in toxicokinetics, in Toxicokinetics and New Drug Development (Yacogi A, Kelly J, and Batra V eds) pp 42-96, Pergamon Press, New York.
    • (1989) Toxicokinetics and New Drug Development , pp. 42-96
    • Mordenti, J.1    Chappell, W.2
  • 260
    • 0032911706 scopus 로고    scopus 로고
    • Memory deficits associated with recreational use of "ecstasy" (MDMA)
    • Morgan MJ (1999) Memory deficits associated with recreational use of "ecstasy" (MDMA). Psychopharmacology 141:30-36.
    • (1999) Psychopharmacology , vol.141 , pp. 30-36
    • Morgan, M.J.1
  • 261
    • 0033778086 scopus 로고    scopus 로고
    • Ecstasy (MDMA): A review of its possible persistent psychological effects
    • Morgan MJ (2000) Ecstasy (MDMA): a review of its possible persistent psychological effects. Psychopharmacology 152:230-248.
    • (2000) Psychopharmacology , vol.152 , pp. 230-248
    • Morgan, M.J.1
  • 262
    • 0036171484 scopus 로고    scopus 로고
    • Ecstasy (MDMA): Are the psychological problems associated with its use reversed by prolonged abstinence?
    • Morgan MJ, McFie L, Fleetwood LH, and Robinson JA (2002) Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence? Psychopharmacology 159:294-303.
    • (2002) Psychopharmacology , vol.159 , pp. 294-303
    • Morgan, M.J.1    McFie, L.2    Fleetwood, L.H.3    Robinson, J.A.4
  • 263
    • 4243984116 scopus 로고    scopus 로고
    • Toxicity of drug abuse - Amphetamine designer drugs (ecstasy): Mental effects and consequences of single dose use
    • Mørland J (2000) Toxicity of drug abuse - amphetamine designer drugs (ecstasy): mental effects and consequences of single dose use. Toxicol Lett (Shannon) 112-113:147-152.
    • (2000) Toxicol Lett (Shannon) , vol.112-113 , pp. 147-152
    • Mørland, J.1
  • 264
    • 0035861913 scopus 로고    scopus 로고
    • Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("ecstasy")
    • Morley KC, Gallate JE, Hunt GE, Mallet PE, and McGregor IS (2001) Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("ecstasy"). Eur J Pharmacol 433:91-99.
    • (2001) Eur J Pharmacol , vol.433 , pp. 91-99
    • Morley, K.C.1    Gallate, J.E.2    Hunt, G.E.3    Mallet, P.E.4    McGregor, I.S.5
  • 265
    • 0034634092 scopus 로고    scopus 로고
    • (±)-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") increases social interaction in rats
    • Morley KC and McGregor IS (2000) (±)-3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") increases social interaction in rats. Eur J Pharmacol 408:41-49.
    • (2000) Eur J Pharmacol , vol.408 , pp. 41-49
    • Morley, K.C.1    McGregor, I.S.2
  • 266
    • 0035968859 scopus 로고    scopus 로고
    • Methamphetamine toxicity in mice is potentiated by exposure to loud music
    • Morton AJ, Hickey MA, and Dean LC (2001) Methamphetamine toxicity in mice is potentiated by exposure to loud music. Neuroreport 12:3277-3281.
    • (2001) Neuroreport , vol.12 , pp. 3277-3281
    • Morton, A.J.1    Hickey, M.A.2    Dean, L.C.3
  • 267
    • 0037165825 scopus 로고    scopus 로고
    • In vitro neuronal and vascular responses to 5-hydroxytryptamine: Modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine
    • Murphy JEJ, Flynn JJ, Cannon DM, Guiry PJ, McCormack P, Baird AW, McBean GJ, and Keenan AK (2002) In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine. Eur J Pharmacol 444:61-67.
    • (2002) Eur J Pharmacol , vol.444 , pp. 61-67
    • Murphy, J.E.J.1    Flynn, J.J.2    Cannon, D.M.3    Guiry, P.J.4    McCormack, P.5    Baird, A.W.6    McBean, G.J.7    Keenan, A.K.8
  • 268
    • 0030458376 scopus 로고    scopus 로고
    • The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine
    • Murray TK, Williams JL, Misra A, Colado MI, and Green AR (1996) The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine. Neuropharmacology 35:1615-1620.
    • (1996) Neuropharmacology , vol.35 , pp. 1615-1620
    • Murray, T.K.1    Williams, J.L.2    Misra, A.3    Colado, M.I.4    Green, A.R.5
  • 269
    • 0019469288 scopus 로고
    • Serotonin and thermoregulation: Old and new views
    • Myers RD (1981) Serotonin and thermoregulation: old and new views. J Physiol (Lond) 77:505-513.
    • (1981) J Physiol (Lond) , vol.77 , pp. 505-513
    • Myers, R.D.1
  • 270
    • 0025695028 scopus 로고
    • Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis
    • Nash JF (1990) Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis. Life Sci 47:2401-2408.
    • (1990) Life Sci , vol.47 , pp. 2401-2408
    • Nash, J.F.1
  • 271
    • 0026326549 scopus 로고
    • Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: Effect of dopamine uptake inhibitors
    • Nash JF and Brodkin J (1991) Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors. J Pharmacol Exp Ther 259:820-825.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 820-825
    • Nash, J.F.1    Brodkin, J.2
  • 272
    • 0023898060 scopus 로고
    • Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine
    • Nash JF, Meltzer HY, and Gudelsky GA (1988) Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 245:873-879.
    • (1988) J Pharmacol Exp Ther , vol.245 , pp. 873-879
    • Nash, J.F.1    Meltzer, H.Y.2    Gudelsky, G.A.3
  • 273
    • 0025739647 scopus 로고
    • Microdialysis studies on 3,4-methylenedioxyamphetamine and structurally related analogues
    • Nash JF and Nichols DE (1991) Microdialysis studies on 3,4-methylenedioxyamphetamine and structurally related analogues. Eur J Pharmacol 200:53-58.
    • (1991) Eur J Pharmacol , vol.200 , pp. 53-58
    • Nash, J.F.1    Nichols, D.E.2
  • 274
    • 0027967140 scopus 로고
    • Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors
    • Nash JF, Roth BL, Brodkin JD, Nichols DE, and Gudelsky GA (1994) Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors. Neurosci Lett 177:111-115.
    • (1994) Neurosci Lett , vol.177 , pp. 111-115
    • Nash, J.F.1    Roth, B.L.2    Brodkin, J.D.3    Nichols, D.E.4    Gudelsky, G.A.5
  • 275
    • 0026696841 scopus 로고
    • Methamphetamine neurotoxicity and striatal glutamate release: Comparison to 3,4-methylenedioxymethamphetamine
    • Nash JF and Yamamoto BK (1992) Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine. Brain Res 581:237-243.
    • (1992) Brain Res , vol.581 , pp. 237-243
    • Nash, J.F.1    Yamamoto, B.K.2
  • 276
    • 0029851272 scopus 로고    scopus 로고
    • Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: Comparative stimulation by hallucinogenic drugs
    • Newton RA, Phipps SL, Flanigan TP, Newberry NR, Carey JE, Kumar C, McDonald B, Chen C, and Elliott JM (1996) Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs. J Neurochem 67:2521-2531.
    • (1996) J Neurochem , vol.67 , pp. 2521-2531
    • Newton, R.A.1    Phipps, S.L.2    Flanigan, T.P.3    Newberry, N.R.4    Carey, J.E.5    Kumar, C.6    McDonald, B.7    Chen, C.8    Elliott, J.M.9
  • 278
    • 0035052951 scopus 로고    scopus 로고
    • Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate
    • Nixdorf WI, Burrows KB, Gudelsky GA, and Yamamoto BK (2001) Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate. J Neurochem 77:647-654.
    • (2001) J Neurochem , vol.77 , pp. 647-654
    • Nixdorf, W.I.1    Burrows, K.B.2    Gudelsky, G.A.3    Yamamoto, B.K.4
  • 279
    • 0032737167 scopus 로고    scopus 로고
    • Serotonin, cerebral blood flow and cerebral metabolic rate in geriatric major depression and normal aging
    • Nobler MS, Mann JJ, and Sackeim HA (1999) Serotonin, cerebral blood flow and cerebral metabolic rate in geriatric major depression and normal aging. Brain Res Rev 30:250-263.
    • (1999) Brain Res Rev , vol.30 , pp. 250-263
    • Nobler, M.S.1    Mann, J.J.2    Sackeim, H.A.3
  • 280
    • 0032559654 scopus 로고    scopus 로고
    • Repeated exposure to methylenedioxymethamphetamine (MDMA) alters nucleus accumbens neuronal responses to dopamine and serotonin
    • Obradovic T, Imel KM, and White SR (1998) Repeated exposure to methylenedioxymethamphetamine (MDMA) alters nucleus accumbens neuronal responses to dopamine and serotonin. Brain Res 785:1-9.
    • (1998) Brain Res , vol.785 , pp. 1-9
    • Obradovic, T.1    Imel, K.M.2    White, S.R.3
  • 281
    • 0034661051 scopus 로고    scopus 로고
    • Cardiovascular and sympathetic responses and reflex changes elicited by MDMA
    • O'Cain PA, Hletko SB, Ogden BA, and Varner KJ (2000) Cardiovascular and sympathetic responses and reflex changes elicited by MDMA. Physiol Behav 70:141-148.
    • (2000) Physiol Behav , vol.70 , pp. 141-148
    • O'Cain, P.A.1    Hletko, S.B.2    Ogden, B.A.3    Varner, K.J.4
  • 282
    • 0027931499 scopus 로고
    • Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse
    • O'Callaghan JP and Miller DB (1994) Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse. J Pharmacol Exp Ther 270:741-751.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 741-751
    • O'Callaghan, J.P.1    Miller, D.B.2
  • 283
    • 0023735752 scopus 로고
    • Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: Immunocytochemical evidence for neurotoxicity
    • O'Hearn E, Battaglia G, De Souza EB, Kuhar MJ, and Molliver ME (1988) Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. J Neurosci 8:2788-2803.
    • (1988) J Neurosci , vol.8 , pp. 2788-2803
    • O'Hearn, E.1    Battaglia, G.2    De Souza, E.B.3    Kuhar, M.J.4    Molliver, M.E.5
  • 284
    • 0035039905 scopus 로고    scopus 로고
    • Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat
    • O'Loinsigh ED, Boland G, Kelly JP, and O'Boyle KM (2001) Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat. Prog Neuropsychopharmacol Biol Psychiatry 25:621-638.
    • (2001) Prog Neuropsychopharmacol Biol Psychiatry , vol.25 , pp. 621-638
    • O'Loinsigh, E.D.1    Boland, G.2    Kelly, J.P.3    O'Boyle, K.M.4
  • 285
    • 0036316571 scopus 로고    scopus 로고
    • Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia
    • O'Shea E, Easton N, Fry JR, Green AR, and Marsden CA (2002) Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia. J Neurochem 81:686-695.
    • (2002) J Neurochem , vol.81 , pp. 686-695
    • O'Shea, E.1    Easton, N.2    Fry, J.R.3    Green, A.R.4    Marsden, C.A.5
  • 286
    • 0035227059 scopus 로고    scopus 로고
    • Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ("ecstasy") on the 5-HT and dopamine concentrations in mouse brain
    • O'Shea E, Esteban B, Camarero J, Green AR, and Colado MI (2001) Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ("ecstasy") on the 5-HT and dopamine concentrations in mouse brain. Neuropharmacology 40:65-74.
    • (2001) Neuropharmacology , vol.40 , pp. 65-74
    • O'Shea, E.1    Esteban, B.2    Camarero, J.3    Green, A.R.4    Colado, M.I.5
  • 287
    • 0031879806 scopus 로고    scopus 로고
    • The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ("ecstasy")
    • O'Shea E, Granados R, Esteban B, Colado MI, and Green AR (1998) The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ("ecstasy"). Neuropharmacology 37:919-926.
    • (1998) Neuropharmacology , vol.37 , pp. 919-926
    • O'Shea, E.1    Granados, R.2    Esteban, B.3    Colado, M.I.4    Green, A.R.5
  • 289
    • 0026598872 scopus 로고
    • Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA)
    • Paris JM and Cunningham KA (1991) Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA). Brain Res Bull 28:115-119.
    • (1991) Brain Res Bull , vol.28 , pp. 115-119
    • Paris, J.M.1    Cunningham, K.A.2
  • 290
    • 0031677797 scopus 로고    scopus 로고
    • Ecstasy (MDMA) effects upon mood and cognition: Before, during and after a Saturday night dance
    • Parrott AC and Lasky J (1998) Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance. Psychopharmacology 139:261-268.
    • (1998) Psychopharmacology , vol.139 , pp. 261-268
    • Parrott, A.C.1    Lasky, J.2
  • 291
    • 0031915719 scopus 로고    scopus 로고
    • Cognitive performance in recreational users of MDMA or ecstasy: Evidence for memory deficits
    • Parrott AC, Lees A, Garnham NJ, Jones M, and Wesnes K (1998) Cognitive performance in recreational users of MDMA or ecstasy: evidence for memory deficits. J Psychopharmacol 12:79-83.
    • (1998) J Psychopharmacol , vol.12 , pp. 79-83
    • Parrott, A.C.1    Lees, A.2    Garnham, N.J.3    Jones, M.4    Wesnes, K.5
  • 292
    • 0036136961 scopus 로고    scopus 로고
    • Recreational ecstasy/MDMA and other drug users from the UK and Italy: Psychiatric symptoms and psychobiological problems
    • Parrott AC, Milani RM, Parmar R, and Turner JJD (2001) Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems. Psychopharmacology 159:77-82.
    • (2001) Psychopharmacology , vol.159 , pp. 77-82
    • Parrott, A.C.1    Milani, R.M.2    Parmar, R.3    Turner, J.J.D.4
  • 293
    • 0343619414 scopus 로고    scopus 로고
    • Psychobiological problems in heavy "ecstasy" (MDMA) poly-drug users
    • Parrott AC, Sisk E, and Turner JJD (2000) Psychobiological problems in heavy "ecstasy" (MDMA) poly-drug users. Drug Alcohol Depend 60:105-110.
    • (2000) Drug Alcohol Depend , vol.60 , pp. 105-110
    • Parrott, A.C.1    Sisk, E.2    Turner, J.J.D.3
  • 294
    • 0030864306 scopus 로고    scopus 로고
    • Ecstasy (MDMA), amphetamine and LSD: Comparative mood profiles in recreational poly-drug users
    • Parrott AC and Stuart M (1997) Ecstasy (MDMA), amphetamine and LSD: comparative mood profiles in recreational poly-drug users. Human Psychopharmacol 12:501-504.
    • (1997) Human Psychopharmacol , vol.12 , pp. 501-504
    • Parrott, A.C.1    Stuart, M.2
  • 295
    • 0023616493 scopus 로고
    • Incidence of recreational use of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on an undergraduate campus
    • Peroutka SJ (1987) Incidence of recreational use of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") on an undergraduate campus. N Engl J Med 317:1542-1543.
    • (1987) N Engl J Med , vol.317 , pp. 1542-1543
    • Peroutka, S.J.1
  • 296
    • 0024241851 scopus 로고
    • Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users
    • Peroutka SJ, Newman H, and Harris H (1988) Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. Neuropsychopharmacology 1:273-277.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 273-277
    • Peroutka, S.J.1    Newman, H.2    Harris, H.3
  • 297
    • 0025111657 scopus 로고
    • Effects of MDMA ("ecstasy") on firing rates of serotonergic, dopaminergic and noradrenergic neurons in the rat
    • Piercey MF, Lum JT, and Palmer JR (1990) Effects of MDMA ("ecstasy") on firing rates of serotonergic, dopaminergic and noradrenergic neurons in the rat. Brain Res 526:203-206.
    • (1990) Brain Res , vol.526 , pp. 203-206
    • Piercey, M.F.1    Lum, J.T.2    Palmer, J.R.3
  • 298
    • 0024558968 scopus 로고
    • Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users
    • Price LH, Ricaurte GA, Krystal JH, and Heninger GR (1989) Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Arch Gen Psychiatry 46:20-22.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 20-22
    • Price, L.H.1    Ricaurte, G.A.2    Krystal, J.H.3    Heninger, G.R.4
  • 299
    • 24544453361 scopus 로고    scopus 로고
    • Acute methylenedioxymethamphetamine administration: Effects on local cerebral blood flow and glucose utilisation in the rat
    • Quate L, McBean DE, Ritchie IM, Olverman HJ, and Kelly PAT (2003) Acute methylenedioxymethamphetamine administration: effects on local cerebral blood flow and glucose utilisation in the rat. Br J Pharmacol 138:197P.
    • (2003) Br J Pharmacol , vol.138
    • Quate, L.1    McBean, D.E.2    Ritchie, I.M.3    Olverman, H.J.4    Kelly, P.A.T.5
  • 301
    • 0026296836 scopus 로고
    • Ecstasy: Towards an understanding of the biochemical basis of the actions of MDMA
    • Rattray M (1991) Ecstasy: towards an understanding of the biochemical basis of the actions of MDMA. Essays Biochem 26:77-87.
    • (1991) Essays Biochem , vol.26 , pp. 77-87
    • Rattray, M.1
  • 302
    • 0029670660 scopus 로고    scopus 로고
    • Naltrindole, a δ-opioid antagonist, blocks MDMA's ability to enhance pressing for rewarding brain stimulation
    • Reid LD, Hubbell CL, Tsai J, Fishkin MD, and Amendola CA (1996) Naltrindole, a δ-opioid antagonist, blocks MDMA's ability to enhance pressing for rewarding brain stimulation. Pharmacol Biochem Behav 53:477-480.
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 477-480
    • Reid, L.D.1    Hubbell, C.L.2    Tsai, J.3    Fishkin, M.D.4    Amendola, C.A.5
  • 306
    • 0034009711 scopus 로고    scopus 로고
    • Memory disturbances in "ecstasy" users are correlated with an altered brain serotonin neurotransmission
    • Reneman L, Booij J, Schmand B, van den Brink W, and Gunning B (2000b) Memory disturbances in "Ecstasy" users are correlated with an altered brain serotonin neurotransmission. Psychopharmacology 148:322-324.
    • (2000) Psychopharmacology , vol.148 , pp. 322-324
    • Reneman, L.1    Booij, J.2    Schmand, B.3    Van den Brink, W.4    Gunning, B.5
  • 308
    • 0034045501 scopus 로고    scopus 로고
    • MDMA ("ecstasy") and its association with cerebrovascular accidents: Preliminary findings
    • Reneman L, Habraken JB, Majoie CB, Booij J, and den Heeten GJ (2000a) MDMA ("Ecstasy") and its association with cerebrovascular accidents: preliminary findings. Am J Neuroradiol 21:1001-1007.
    • (2000) Am J Neuroradiol , vol.21 , pp. 1001-1007
    • Reneman, L.1    Habraken, J.B.2    Majoie, C.B.3    Booij, J.4    Den Heeten, G.J.5
  • 309
    • 0036168326 scopus 로고    scopus 로고
    • Reduced N-acetylaspartate levels in the frontal cortex of 3,4-methylenedioxymethamphetamine (ecstasy) users: Preliminary results
    • Reneman L, Majoie CBLM, Flick H, and den Heeten GJ (2002c) Reduced N-acetylaspartate levels in the frontal cortex of 3,4-methylenedioxymethamphetamine (ecstasy) users: preliminary results. Am J Neuroradiol 23:231-237.
    • (2002) Am J Neuroradiol , vol.23 , pp. 231-237
    • Reneman, L.1    Majoie, C.B.L.M.2    Flick, H.3    Den Heeten, G.J.4
  • 310
    • 0022357597 scopus 로고
    • Hallucinogenic amphetamine selectively destroys brain serotonin nerve terminals
    • Ricaurte G, Bryan G, Strauss L, Seiden L, and Schuster C (1985) Hallucinogenic amphetamine selectively destroys brain serotonin nerve terminals. Science (Wash DC) 229:986-988.
    • (1985) Science (Wash DC) , vol.229 , pp. 986-988
    • Ricaurte, G.1    Bryan, G.2    Strauss, L.3    Seiden, L.4    Schuster, C.5
  • 311
    • 0023797477 scopus 로고
    • 5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates
    • Ricaurte GA, DeLanney LE, Wiener SG, Irwin I, and Langston JW (1988a) 5-hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates. Brain Res 474:2359-2363.
    • (1988) Brain Res , vol.474 , pp. 2359-2363
    • Ricaurte, G.A.1    DeLanney, L.E.2    Wiener, S.G.3    Irwin, I.4    Langston, J.W.5
  • 312
    • 0023902232 scopus 로고
    • Toxic effects of MDMA on central serotonergic neurons in the primate: Importance of route and frequency of drug administration
    • Ricaurte GA, DeLanney LE, Irwin I, and Langston JW (1988c) Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration. Brain Res 446:165-168.
    • (1988) Brain Res , vol.446 , pp. 165-168
    • Ricaurte, G.A.1    DeLanney, L.E.2    Irwin, I.3    Langston, J.W.4
  • 314
    • 0026612759 scopus 로고
    • Lasting effects of (±)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: Neurochemical observations
    • Ricaurte GA, Martello AL, Katz JL, and Martello MB (1992) Lasting effects of (±)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations. J Pharmacol Exp Ther 261:616-622.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 616-622
    • Ricaurte, G.A.1    Martello, A.L.2    Katz, J.L.3    Martello, M.B.4
  • 315
    • 0026759002 scopus 로고
    • Neurotoxic amphetamine analogues: Effects in monkeys and implications for humans
    • Ricaurte GA and McCann UD (1992) Neurotoxic amphetamine analogues: effects in monkeys and implications for humans. Ann NY Acad Sci 648:371-382.
    • (1992) Ann NY Acad Sci , vol.648 , pp. 371-382
    • Ricaurte, G.A.1    McCann, U.D.2
  • 316
    • 0034653370 scopus 로고    scopus 로고
    • Toxicodynamics and long-term toxicity of the recreational drug, 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Ricaurte GA, McCann UD, Szabo Z, and Scheffel U (2000) Toxicodynamics and long-term toxicity of the recreational drug, 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). Toxicol Lett (Shannon) 112-113:143-146.
    • (2000) Toxicol Lett (Shannon) , vol.112-113 , pp. 143-146
    • Ricaurte, G.A.1    McCann, U.D.2    Szabo, Z.3    Scheffel, U.4
  • 317
    • 0037183866 scopus 로고    scopus 로고
    • Severe dopaminergic neurotoxicity in primates after a single recreational dose regimen of MDMA ("ecstasy")
    • Ricaurte GA, Yuan J, Hatzidimitriou G, Cord BJ, and McCann UD (2002) Severe dopaminergic neurotoxicity in primates after a single recreational dose regimen of MDMA ("Ecstasy"). Science (Wash DC) 297:2260-2263.
    • (2002) Science (Wash DC) , vol.297 , pp. 2260-2263
    • Ricaurte, G.A.1    Yuan, J.2    Hatzidimitriou, G.3    Cord, B.J.4    McCann, U.D.5
  • 318
    • 0033902801 scopus 로고    scopus 로고
    • Cognitive performance amongst recreational users of "ecstasy"
    • Rodgers J (2000) Cognitive performance amongst recreational users of "ecstasy". Psychopharmacology 151:19-24.
    • (2000) Psychopharmacology , vol.151 , pp. 19-24
    • Rodgers, J.1
  • 319
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI, and Partilla JS (2001) Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39:32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 320
    • 0029869092 scopus 로고    scopus 로고
    • Fenfluramine-induced activation of the immediate-early gene c-fos in the striatum: Possible interaction between serotonin and dopamine
    • Rouillard C, Bovetto S, Gervais J, and Richard D (1996) Fenfluramine-induced activation of the immediate-early gene c-fos in the striatum: possible interaction between serotonin and dopamine. Brain Res Mol Brain Res 37:105-115.
    • (1996) Brain Res Mol Brain Res , vol.37 , pp. 105-115
    • Rouillard, C.1    Bovetto, S.2    Gervais, J.3    Richard, D.4
  • 321
    • 0027204246 scopus 로고
    • Loss of serotonin uptake sites and immunoreactivity in rat cortex after dexfenfluramine occur without parallel glial cell reactions
    • Rowland NE, Kalehua AN, Li BH, Semple-Rowland SL, and Streit WJ (1993) Loss of serotonin uptake sites and immunoreactivity in rat cortex after dexfenfluramine occur without parallel glial cell reactions. Brain Res 624:35-43.
    • (1993) Brain Res , vol.624 , pp. 35-43
    • Rowland, N.E.1    Kalehua, A.N.2    Li, B.H.3    Semple-Rowland, S.L.4    Streit, W.J.5
  • 322
    • 0030611020 scopus 로고    scopus 로고
    • The pathology of the ring-substituted amphetamine analogue 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Rutty GN and Milroy CM (1997) The pathology of the ring-substituted amphetamine analogue 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). J Pathol 181:255-256.
    • (1997) J Pathol , vol.181 , pp. 255-256
    • Rutty, G.N.1    Milroy, C.M.2
  • 323
    • 0030087890 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations
    • Sabol KE, Lew R, Richards JB, Vosmer GL, and Seiden LS (1996) Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: synaptosomal uptake and tissue concentrations. J Pharmacol Exp Ther 276:846-854.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 846-854
    • Sabol, K.E.1    Lew, R.2    Richards, J.B.3    Vosmer, G.L.4    Seiden, L.S.5
  • 324
    • 0032556069 scopus 로고    scopus 로고
    • Reserpine attenuates D-amphetamine and MDMA-induced transmitter release in vivo: A consideration of dose, core temperature and dopamine synthesis
    • Sabol KE and Seiden LS (1998) Reserpine attenuates D-amphetamine and MDMA-induced transmitter release in vivo: a consideration of dose, core temperature and dopamine synthesis. Brain Res 806:69-78.
    • (1998) Brain Res , vol.806 , pp. 69-78
    • Sabol, K.E.1    Seiden, L.S.2
  • 326
    • 0031900822 scopus 로고    scopus 로고
    • Responses of the nervous system to low frequency stimulation and EEG rhythms: Clinical implications
    • Salansky N, Fedotchev A, and Bondar A (1998) Responses of the nervous system to low frequency stimulation and EEG rhythms: clinical implications. Neurosci Biobehav Rev 22:395-409.
    • (1998) Neurosci Biobehav Rev , vol.22 , pp. 395-409
    • Salansky, N.1    Fedotchev, A.2    Bondar, A.3
  • 327
    • 0031888342 scopus 로고    scopus 로고
    • 2A receptors in rat thermoregulatory mechanisms
    • 2A receptors in rat thermoregulatory mechanisms. Pharmacol Toxicol 82:122-127.
    • (1998) Pharmacol Toxicol , vol.82 , pp. 122-127
    • Salmi, P.1    Ahlenius, S.2
  • 328
    • 0034852341 scopus 로고    scopus 로고
    • The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ("ecstasy")-induced degeneration of 5-HT nerve endings in rat brain
    • Sanchez V, Camarero J, Esteban B, Peter MJ, Green AR, and Colado MI (2001) The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ("ecstasy")-induced degeneration of 5-HT nerve endings in rat brain. Br J Pharmacol 134:46-57.
    • (2001) Br J Pharmacol , vol.134 , pp. 46-57
    • Sanchez, V.1    Camarero, J.2    Esteban, B.3    Peter, M.J.4    Green, A.R.5    Colado, M.I.6
  • 329
    • 0037333409 scopus 로고    scopus 로고
    • Differential effect of dietary selenium on the long term neurotoxicity induced by MDMA in mice and rats
    • Sanchez V, Camarero J, O'Shea E, Green AR, and Colado MI (2003) Differential effect of dietary selenium on the long term neurotoxicity induced by MDMA in mice and rats. Neuropharmacology 44:449-461.
    • (2003) Neuropharmacology , vol.44 , pp. 449-461
    • Sanchez, V.1    Camarero, J.2    O'Shea, E.3    Green, A.R.4    Colado, M.I.5
  • 330
    • 0030591619 scopus 로고    scopus 로고
    • No evidence of neurotoxicity exists
    • Saunders N (1996) No evidence of neurotoxicity exists. Br Med J 313:423.
    • (1996) Br Med J , vol.313 , pp. 423
    • Saunders, N.1
  • 334
  • 335
    • 0025936650 scopus 로고
    • Chronic atypical psychosis associated with MDMA ("ecstasy") abuse
    • Schifano F (1991) Chronic atypical psychosis associated with MDMA ("ecstasy") abuse. Lancet 338:1335.
    • (1991) Lancet , vol.338 , pp. 1335
    • Schifano, F.1
  • 336
    • 0023163857 scopus 로고
    • Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine
    • Schmidt CJ (1987a) Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. J Pharmacol Exp Ther 240:1-7.
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 1-7
    • Schmidt, C.J.1
  • 337
    • 0023178885 scopus 로고
    • Acute administration of methylenedioxymethamphetamine: Comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs
    • Schmidt CJ (1987b) Acute administration of methylenedioxymethamphetamine: comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs. Eur J Pharmacol 136:81-88.
    • (1987) Eur J Pharmacol , vol.136 , pp. 81-88
    • Schmidt, C.J.1
  • 338
    • 0025196107 scopus 로고
    • 2 receptor antagonists protect against the neurotoxicity of methylenedioxymethamphetamine in rats
    • 2 receptor antagonists protect against the neurotoxicity of methylenedioxymethamphetamine in rats. J Pharmacol Exp Ther 255:478-483.
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 478-483
    • Schmidt, C.J.1    Abbate, G.M.2    Black, C.K.3    Taylor, V.L.4
  • 340
    • 0025288621 scopus 로고
    • Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine
    • Schmidt CJ, Black CK, and Taylor VL (1990c) Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine. Eur J Pharmacol 181:59-70.
    • (1990) Eur J Pharmacol , vol.181 , pp. 59-70
    • Schmidt, C.J.1    Black, C.K.2    Taylor, V.L.3
  • 341
    • 0025650064 scopus 로고
    • Neurotoxicity of MDMA: Neurochemical effects
    • Schmidt CJ and Kehne JH (1990) Neurotoxicity of MDMA: neurochemical effects. Ann NY Acad Sci 600:665-681.
    • (1990) Ann NY Acad Sci , vol.600 , pp. 665-681
    • Schmidt, C.J.1    Kehne, J.H.2
  • 342
    • 0023109989 scopus 로고
    • In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain
    • Schmidt CJ, Levin JA, and Lovenberg W (1987) In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain. Biochem Pharmacol 36:747-755.
    • (1987) Biochem Pharmacol , vol.36 , pp. 747-755
    • Schmidt, C.J.1    Levin, J.A.2    Lovenberg, W.3
  • 343
    • 0023475168 scopus 로고
    • Depression of rat brain tryptophan hydroxylase following the acute administration of methylenedioxymethamphetamine
    • Schmidt CJ and Taylor VL (1987) Depression of rat brain tryptophan hydroxylase following the acute administration of methylenedioxymethamphetamine. Biochem Pharmacol 36:4095-4102.
    • (1987) Biochem Pharmacol , vol.36 , pp. 4095-4102
    • Schmidt, C.J.1    Taylor, V.L.2
  • 344
    • 0023709159 scopus 로고
    • Direct central effects of acute methylenedioxymethamphetamine on serotonergic neurons
    • Schmidt CJ and Taylor VL (1988) Direct central effects of acute methylenedioxymethamphetamine on serotonergic neurons. Eur J Pharmacol 156:121-131.
    • (1988) Eur J Pharmacol , vol.156 , pp. 121-131
    • Schmidt, C.J.1    Taylor, V.L.2
  • 345
    • 0025924856 scopus 로고
    • 2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: Reversal by L-DOPA
    • 2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-DOPA. J Pharmacol Exp Ther 256:230-235.
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 230-235
    • Schmidt, C.J.1    Taylor, V.L.2    Abbate, G.M.3    Nieduzak, T.R.4
  • 346
    • 0022486506 scopus 로고
    • Methylenedioxymethamphetamine: A potentially neurotoxic amphetamine analogue
    • Schmidt CJ, Wu L, and Lovenberg W (1986) Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue. Eur J Pharmacol 124:175-178.
    • (1986) Eur J Pharmacol , vol.124 , pp. 175-178
    • Schmidt, C.J.1    Wu, L.2    Lovenberg, W.3
  • 348
    • 0032985047 scopus 로고    scopus 로고
    • Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ("ecstasy") users
    • Semple DM, Ebmeier KP, Glabus MF, O'Carroll RE, and Johnstone EC (1999) Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ("ecstasy") users. Br J Psychiatry 175:63-69.
    • (1999) Br J Psychiatry , vol.175 , pp. 63-69
    • Semple, D.M.1    Ebmeier, K.P.2    Glabus, M.F.3    O'Carroll, R.E.4    Johnstone, E.C.5
  • 349
    • 0031770835 scopus 로고    scopus 로고
    • Effect of 3,4-methylenedioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin
    • Shankaran M and Gudelsky GA (1998) Effect of 3,4-methylenedioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin. Pharmacol Biochem Behav 61:361-366.
    • (1998) Pharmacol Biochem Behav , vol.61 , pp. 361-366
    • Shankaran, M.1    Gudelsky, G.A.2
  • 350
    • 0033986934 scopus 로고    scopus 로고
    • A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration
    • Shankaran M and Gudelsky GA (1999) A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration. Psychopharmacology 147:66-72.
    • (1999) Psychopharmacology , vol.147 , pp. 66-72
    • Shankaran, M.1    Gudelsky, G.A.2
  • 351
    • 0032763755 scopus 로고    scopus 로고
    • Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine
    • Shankaran M, Yamamoto BK, and Gudelsky GA (1999a) Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine. Eur J Pharmacol 385:103-110.
    • (1999) Eur J Pharmacol , vol.385 , pp. 103-110
    • Shankaran, M.1    Yamamoto, B.K.2    Gudelsky, G.A.3
  • 352
    • 0033049348 scopus 로고    scopus 로고
    • Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum
    • Shankaran M, Yamamoto BK, and Gudelsky GA (1999b) Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum. J Neurochem 72:2516-2522.
    • (1999) J Neurochem , vol.72 , pp. 2516-2522
    • Shankaran, M.1    Yamamoto, B.K.2    Gudelsky, G.A.3
  • 353
    • 0035123882 scopus 로고    scopus 로고
    • Ascorbic acid prevents 3,4-methylenedioxymethamphetamine (MDMA)-induced hydroxyl radical formation and the behavioral and neurochemical consequences of the depletion of brain 5-HT
    • Shankaran M, Yamamoto BK, and Gudelsky GA (2001) Ascorbic acid prevents 3,4-methylenedioxymethamphetamine (MDMA)-induced hydroxyl radical formation and the behavioral and neurochemical consequences of the depletion of brain 5-HT. Synapse 40:55-64.
    • (2001) Synapse , vol.40 , pp. 55-64
    • Shankaran, M.1    Yamamoto, B.K.2    Gudelsky, G.A.3
  • 354
    • 0026643617 scopus 로고
    • In vivo measurement of hypothalamic serotonin release by intracerebral microdialysis: Significant enhancement by immobilization stress in rats
    • Shimizu N, Take S, Hori T, and Oomura Y (1992) In vivo measurement of hypothalamic serotonin release by intracerebral microdialysis: significant enhancement by immobilization stress in rats. Brain Res Bull 28:727-734.
    • (1992) Brain Res Bull , vol.28 , pp. 727-734
    • Shimizu, N.1    Take, S.2    Hori, T.3    Oomura, Y.4
  • 355
    • 0034714205 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy)-induced egr-1 mRNA in rat brain: Pharmacological manipulation
    • Shirayama Y, Hashimoto K, Iyo M, Watanabe K, Higuchi T, and Minabe Y (2000) 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-induced egr-1 mRNA in rat brain: pharmacological manipulation. Eur J Pharmacol 402:215-222.
    • (2000) Eur J Pharmacol , vol.402 , pp. 215-222
    • Shirayama, Y.1    Hashimoto, K.2    Iyo, M.3    Watanabe, K.4    Higuchi, T.5    Minabe, Y.6
  • 356
    • 0002791501 scopus 로고
    • Characterization of three new psychomimetics
    • (Stillman RC and Willette RE eds), Pergamon Press, Oxford
    • Shulgin AT and Nichols DE (1978) Characterization of three new psychomimetics, in The Psychopharmacology of Hallucinogens (Stillman RC and Willette RE eds), Pergamon Press, Oxford.
    • (1978) The Psychopharmacology of Hallucinogens
    • Shulgin, A.T.1    Nichols, D.E.2
  • 357
    • 0019403504 scopus 로고
    • Methylenedioxymethamphetamine. Clinical description of overdose, death and review of pharmacology
    • Simpson DL and Rumack BH (1981) Methylenedioxymethamphetamine. Clinical description of overdose, death and review of pharmacology. Arch Intern Med 141:1507-1509.
    • (1981) Arch Intern Med , vol.141 , pp. 1507-1509
    • Simpson, D.L.1    Rumack, B.H.2
  • 358
    • 0023811368 scopus 로고
    • Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)
    • Slikker W Jr, Ali SF, Scallet AC, Frith CH, Newport GD, and Bailey JR (1988) Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA). Toxicol Appl Pharmacol 96:448-457.
    • (1988) Toxicol Appl Pharmacol , vol.96 , pp. 448-457
    • Slikker W., Jr.1    Ali, S.F.2    Scallet, A.C.3    Frith, C.H.4    Newport, G.D.5    Bailey, J.R.6
  • 360
    • 0026710950 scopus 로고
    • Recreational MDMA use in Sydney: A profile of "ecstasy" users and their experiences with the drug
    • Solowij N, Hall W, and Lee N (1992) Recreational MDMA use in Sydney: a profile of "Ecstasy" users and their experiences with the drug. Br J Addict 87:1161-1172.
    • (1992) Br J Addict , vol.87 , pp. 1161-1172
    • Solowij, N.1    Hall, W.2    Lee, N.3
  • 361
    • 0001425882 scopus 로고
    • Reconciling the role of central serotonin neurons in human and animal behaviour
    • Soubrie P (1986) Reconciling the role of central serotonin neurons in human and animal behaviour. Behav Brain Sci 9:319-364.
    • (1986) Behav Brain Sci , vol.9 , pp. 319-364
    • Soubrie, P.1
  • 362
    • 0024323182 scopus 로고
    • Acute and subchronic effects of methylenedioxymethamphetamine [(±)MDMA] on locomotion and serotonin syndrome behaviour in the rat
    • Spanos LJ and Yamamoto BK (1989) Acute and subchronic effects of methylenedioxymethamphetamine [(±)MDMA] on locomotion and serotonin syndrome behaviour in the rat. Pharmacol Biochem Behav 32:835-840.
    • (1989) Pharmacol Biochem Behav , vol.32 , pp. 835-840
    • Spanos, L.J.1    Yamamoto, B.K.2
  • 363
    • 0031749512 scopus 로고    scopus 로고
    • An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine
    • Sprague JE, Everman SL, and Nichols DE (1998) An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine. Neurotoxicology 19:427-442.
    • (1998) Neurotoxicology , vol.19 , pp. 427-442
    • Sprague, J.E.1    Everman, S.L.2    Nichols, D.E.3
  • 364
    • 0029078456 scopus 로고
    • The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits
    • Sprague JE and Nichols DE (1995) The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. J Pharmacol Exp Ther 273:667-673.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 667-673
    • Sprague, J.E.1    Nichols, D.E.2
  • 365
    • 0023228746 scopus 로고
    • Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain
    • Steele TD, Nichols DE, and Yim GK (1987) Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain. Biochem Pharmacol 36:2297-2303.
    • (1987) Biochem Pharmacol , vol.36 , pp. 2297-2303
    • Steele, T.D.1    Nichols, D.E.2    Yim, G.K.3
  • 366
    • 0032776858 scopus 로고    scopus 로고
    • Effects of "ecstasy" blocked by serotonin reuptake inhibitors
    • Stein DJ and Rink J (1999) Effects of "Ecstasy" blocked by serotonin reuptake inhibitors. J Clin Psychiatry 60:485.
    • (1999) J Clin Psychiatry , vol.60 , pp. 485
    • Stein, D.J.1    Rink, J.2
  • 367
    • 0032995147 scopus 로고    scopus 로고
    • The distribution of 3,4-methylenedioxymethamphetamine "ecstasy"-induced c-fos expression in rat brain
    • Stephenson CP, Hunt GE, Topple AN, and McGregor IS (1999) The distribution of 3,4-methylenedioxymethamphetamine "Ecstasy"-induced c-fos expression in rat brain. Neuroscience 92:1011-1023.
    • (1999) Neuroscience , vol.92 , pp. 1011-1023
    • Stephenson, C.P.1    Hunt, G.E.2    Topple, A.N.3    McGregor, I.S.4
  • 368
    • 0023119513 scopus 로고
    • Effect of cysteine on the persistent depletion of brain monoamines by amphetamine, p-chloroamphetamine and MPTP
    • Steranka LR and Rhind AW (1987) Effect of cysteine on the persistent depletion of brain monoamines by amphetamine, p-chloroamphetamine and MPTP. Eur J Pharmacol 133:191-197.
    • (1987) Eur J Pharmacol , vol.133 , pp. 191-197
    • Steranka, L.R.1    Rhind, A.W.2
  • 369
    • 0035912719 scopus 로고    scopus 로고
    • A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites
    • Steward O and Worley PF (2001) A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites. Proc Natl Acad Sci USA 98:7062-7068.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7062-7068
    • Steward, O.1    Worley, P.F.2
  • 371
    • 0023522125 scopus 로고
    • Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats
    • Stone DM, Hanson GR, and Gibb JW (1987a) Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats. Neuropharmacology 26:1657-1661.
    • (1987) Neuropharmacology , vol.26 , pp. 1657-1661
    • Stone, D.M.1    Hanson, G.R.2    Gibb, J.W.3
  • 372
    • 0023154112 scopus 로고
    • A comparison of the neurotoxic potential of methylenedioxymethamphetamine (MDA) and its N-methylated and N-ethylated derivatives
    • Stone DM, Johnson M, Hanson GR, and Gibb JW (1987b) A comparison of the neurotoxic potential of methylenedioxymethamphetamine (MDA) and its N-methylated and N-ethylated derivatives. Eur J Pharmacol 134:245-248.
    • (1987) Eur J Pharmacol , vol.134 , pp. 245-248
    • Stone, D.M.1    Johnson, M.2    Hanson, G.R.3    Gibb, J.W.4
  • 373
    • 0023791701 scopus 로고
    • Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine
    • Stone DM, Johnson M, Hanson GR, and Gibb JW (1988) Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 247:79-87.
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 79-87
    • Stone, D.M.1    Johnson, M.2    Hanson, G.R.3    Gibb, J.W.4
  • 374
    • 0024420906 scopus 로고
    • Acute inactivation of tryptophan hydroxylase by amphetamine analogs involves the oxidation of sulphydryl sites
    • Stone DM, Johnson M, Hanson GR, and Gibb JW (1989) Acute inactivation of tryptophan hydroxylase by amphetamine analogs involves the oxidation of sulphydryl sites. Eur J Pharmacol 172:93-97.
    • (1989) Eur J Pharmacol , vol.172 , pp. 93-97
    • Stone, D.M.1    Johnson, M.2    Hanson, G.R.3    Gibb, J.W.4
  • 375
    • 0023484528 scopus 로고
    • Immediate and long term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat
    • Stone DM, Merchant KM, Hanson GR, and Gibb JW (1987c) Immediate and long term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat. Neuropharmacology 26:1677-1683.
    • (1987) Neuropharmacology , vol.26 , pp. 1677-1683
    • Stone, D.M.1    Merchant, K.M.2    Hanson, G.R.3    Gibb, J.W.4
  • 376
    • 0022911033 scopus 로고
    • The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain
    • Stone DM, Stahl DC, Hanson GR, and Gibb JW (1986) The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain. Eur J Pharmacol 128:41-48.
    • (1986) Eur J Pharmacol , vol.128 , pp. 41-48
    • Stone, D.M.1    Stahl, D.C.2    Hanson, G.R.3    Gibb, J.W.4
  • 377
    • 0036137983 scopus 로고    scopus 로고
    • Increasing MDMA use among college students: Results of a national survey
    • Strote J, Lee JE, and Wechsler H (2002) Increasing MDMA use among college students: results of a national survey. J Adolesc Health 30:64-72.
    • (2002) J Adolesc Health , vol.30 , pp. 64-72
    • Strote, J.1    Lee, J.E.2    Wechsler, H.3
  • 378
    • 0035798392 scopus 로고    scopus 로고
    • Involvement of serotonergic and dopaminergic mechanisms in hyperthermia induced by a serotonin-releasing drug, p-chloroamphetamine in mice
    • Sugimoto Y, Ohkura M, Inoue K, and Yamada J (2001) Involvement of serotonergic and dopaminergic mechanisms in hyperthermia induced by a serotonin-releasing drug, p-chloroamphetamine in mice. Eur J Pharmacol 430:265-268.
    • (2001) Eur J Pharmacol , vol.430 , pp. 265-268
    • Sugimoto, Y.1    Ohkura, M.2    Inoue, K.3    Yamada, J.4
  • 382
    • 0043027635 scopus 로고
    • 1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamine)tetraline in the rat
    • 1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamine)tetraline in the rat. Eur J Pharmacol 76:81-85.
    • (1984) Eur J Pharmacol , vol.76 , pp. 81-85
    • Tricklebank, M.D.1    Forler, C.2    Fozard, J.R.3
  • 384
    • 0033574984 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine ("ecstasy") stimulates the expression of α1 (I) procollagen mRNA in hepatic stellate cells
    • Varela-Rey M, Montiel-Duarte C, Beitia G, Cenarruzabeitia E, and Iraburu MJ (1999) 3,4-methylenedioxymethamphetamine ("Ecstasy") stimulates the expression of α1 (I) procollagen mRNA in hepatic stellate cells. Biochem Biophys Res Commun 259:678-682.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 678-682
    • Varela-Rey, M.1    Montiel-Duarte, C.2    Beitia, G.3    Cenarruzabeitia, E.4    Iraburu, M.J.5
  • 385
    • 0036239860 scopus 로고    scopus 로고
    • Sub-acute effects of MDMA (±3,4-methylenedioxymethamphetamine "ecstasy") on mood: Evidence of gender differences
    • Verheyden SL, Hadfield J, Calin T, and Curran HV (2002) Sub-acute effects of MDMA (±3,4-methylenedioxymethamphetamine "ecstasy") on mood: evidence of gender differences. Psychopharmacology 161:23-31.
    • (2002) Psychopharmacology , vol.161 , pp. 23-31
    • Verheyden, S.L.1    Hadfield, J.2    Calin, T.3    Curran, H.V.4
  • 388
    • 0031783570 scopus 로고    scopus 로고
    • Psychological and cardiovascular effects and short-term sequelae of MDMA (ecstasy) in MDMA-naïve healthy volunteers
    • Vollenweider FX, Gamma A, Liechti M, and Huber T (1998) Psychological and cardiovascular effects and short-term sequelae of MDMA (ecstasy) in MDMA-naïve healthy volunteers. Neuropsychopharmacology 19:241-251.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 241-251
    • Vollenweider, F.X.1    Gamma, A.2    Liechti, M.3    Huber, T.4
  • 390
    • 0032924820 scopus 로고    scopus 로고
    • Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans
    • Vollenweider FX, Remensberger S, Hell D, and Geyer MA (1999) Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans. Psychopharmacology 143:365-372.
    • (1999) Psychopharmacology , vol.143 , pp. 365-372
    • Vollenweider, F.X.1    Remensberger, S.2    Hell, D.3    Geyer, M.A.4
  • 391
  • 392
    • 0035144538 scopus 로고    scopus 로고
    • Alterations in diurnal and nocturnal locomotor activity in rats treated with a monoamine-depleting regimen of methamphetamine or 3,4-methylenedioxymethamphetamine
    • Wallace TL, Gudelsky GA, and Vorhees CV (2001) Alterations in diurnal and nocturnal locomotor activity in rats treated with a monoamine-depleting regimen of methamphetamine or 3,4-methylenedioxymethamphetamine. Psychopharmacology 153:321-326.
    • (2001) Psychopharmacology , vol.153 , pp. 321-326
    • Wallace, T.L.1    Gudelsky, G.A.2    Vorhees, C.V.3
  • 393
    • 0013010643 scopus 로고    scopus 로고
    • Working memory deficits in current and previous users of MDMA (ecstasy)
    • Wareing M, Fisk JE, and Murphy PN (2000) Working memory deficits in current and previous users of MDMA (Ecstasy). Br J Psychol 91:181-188.
    • (2000) Br J Psychol , vol.91 , pp. 181-188
    • Wareing, M.1    Fisk, J.E.2    Murphy, P.N.3
  • 394
    • 0030571203 scopus 로고    scopus 로고
    • Alcohol and drug use in UK university students
    • Webb E, Ashton CH, Kelly P, and Kamali F (1996) Alcohol and drug use in UK university students. Lancet 348:922-925.
    • (1996) Lancet , vol.348 , pp. 922-925
    • Webb, E.1    Ashton, C.H.2    Kelly, P.3    Kamali, F.4
  • 396
    • 0024310009 scopus 로고
    • Effects of methylenedioxymethamphetamine on local cerebral glucose utilization in the rat
    • Wilkerson G and London ED (1989) Effects of methylenedioxymethamphetamine on local cerebral glucose utilization in the rat. Neuropharmacology 28:1129-1138.
    • (1989) Neuropharmacology , vol.28 , pp. 1129-1138
    • Wilkerson, G.1    London, E.D.2
  • 398
    • 0028428908 scopus 로고
    • Microglial response to degeneration of serotonergic axon terminals
    • Wilson MA and Molliver ME (1994) Microglial response to degeneration of serotonergic axon terminals. Glia 11:18-34.
    • (1994) Glia , vol.11 , pp. 18-34
    • Wilson, M.A.1    Molliver, M.E.2
  • 399
    • 0024541227 scopus 로고
    • Distinct morphologic classes of serotonergic axons in primates exhibit differential vulnerability to the psychotropic drug 3,4-methylenedioxymethamphetamine
    • Wilson MA, Ricaurte GA, and Molliver ME (1989) Distinct morphologic classes of serotonergic axons in primates exhibit differential vulnerability to the psychotropic drug 3,4-methylenedioxymethamphetamine. Neuroscience 28:121-137.
    • (1989) Neuroscience , vol.28 , pp. 121-137
    • Wilson, M.A.1    Ricaurte, G.A.2    Molliver, M.E.3
  • 400
    • 0036173285 scopus 로고    scopus 로고
    • Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration
    • Winsauer PJ, McCann UD, Yuan J, Delatte MS, Stevenson MW, Ricaurte GA, and Moerschbaecher JM (2002) Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration. Psychopharmacology 159:388-396.
    • (2002) Psychopharmacology , vol.159 , pp. 388-396
    • Winsauer, P.J.1    McCann, U.D.2    Yuan, J.3    Delatte, M.S.4    Stevenson, M.W.5    Ricaurte, G.A.6    Moerschbaecher, J.M.7
  • 401
    • 0035452496 scopus 로고    scopus 로고
    • Drugs and the dance music scene: A survey of current drug use patterns among a sample of dance music enthusiasts in the UK
    • Winstock AR, Griffiths P, and Stewart D (2001) Drugs and the dance music scene: a survey of current drug use patterns among a sample of dance music enthusiasts in the UK. Drug Alcohol Depend 64:9-17.
    • (2001) Drug Alcohol Depend , vol.64 , pp. 9-17
    • Winstock, A.R.1    Griffiths, P.2    Stewart, D.3
  • 402
    • 0015618474 scopus 로고
    • Hyperthermia and the amphetamine aggregation phenomenon: Absence of a causal relation
    • Wolf HH and Bunce ME (1973) Hyperthermia and the amphetamine aggregation phenomenon: absence of a causal relation. J Pharm Pharmacol 25:425-427.
    • (1973) J Pharm Pharmacol , vol.25 , pp. 425-427
    • Wolf, H.H.1    Bunce, M.E.2
  • 403
    • 0023870334 scopus 로고
    • The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat
    • Yamamoto BK and Spanos LJ (1988) The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat. Eur J Pharmacol 148:195-203.
    • (1988) Eur J Pharmacol , vol.148 , pp. 195-203
    • Yamamoto, B.K.1    Spanos, L.J.2
  • 404
    • 0029037007 scopus 로고
    • Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and γ-aminobutyric acid in the substantia nigra
    • Yamamoto BK, Nash JF, and Gudelsky GA (1995) Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and γ-aminobutyric acid in the substantia nigra. J Pharmacol Exp Ther 273:1063-1070.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 1063-1070
    • Yamamoto, B.K.1    Nash, J.F.2    Gudelsky, G.A.3
  • 405
    • 0021064512 scopus 로고
    • Dopaminergic and serotonergic mechanisms of thermoregulation: Mediation of thermal effects of apomorphine and dopamine
    • Yamawaki S, Lai H, and Horita A (1983) Dopaminergic and serotonergic mechanisms of thermoregulation: mediation of thermal effects of apomorphine and dopamine. J Pharmacol Exp Ther 227:383-388.
    • (1983) J Pharmacol Exp Ther , vol.227 , pp. 383-388
    • Yamawaki, S.1    Lai, H.2    Horita, A.3
  • 406
    • 0030798269 scopus 로고    scopus 로고
    • Effects of salicylate on 3,4-methylenedioxymethamphetamine (MDMA) -induced neurotoxicity in rats
    • Yeh SY (1997) Effects of salicylate on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats. Pharmacol Biochem Behav 58:701-708.
    • (1997) Pharmacol Biochem Behav , vol.58 , pp. 701-708
    • Yeh, S.Y.1
  • 407
    • 0033103959 scopus 로고    scopus 로고
    • N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats
    • Yeh SY (1999) N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats. Synapse 31:169-177.
    • (1999) Synapse , vol.31 , pp. 169-177
    • Yeh, S.Y.1
  • 408
    • 0026007004 scopus 로고
    • The neurochemical and stimulatory effects of putative metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in rats
    • Yeh SY and Hsu FL (1991) The neurochemical and stimulatory effects of putative metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in rats. Pharmacol Biochem Behav 39:787-790.
    • (1991) Pharmacol Biochem Behav , vol.39 , pp. 787-790
    • Yeh, S.Y.1    Hsu, F.L.2
  • 409
    • 0035006623 scopus 로고    scopus 로고
    • Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity
    • Yuan J, Callahan BY, McCann UD, and Ricaurte GA (2001) Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity. J Neurochem 77:1338-1347.
    • (2001) J Neurochem , vol.77 , pp. 1338-1347
    • Yuan, J.1    Callahan, B.Y.2    McCann, U.D.3    Ricaurte, G.A.4
  • 410
    • 0036325724 scopus 로고    scopus 로고
    • Effect of depleting vesicular and cytoplasmic dopamine on methylenedioxymethamphetamine neurotoxicity
    • Yuan J, Cord BJ, McCann UD, Callahan T, and Ricaurte GA (2002) Effect of depleting vesicular and cytoplasmic dopamine on methylenedioxymethamphetamine neurotoxicity. J Neurochem 80:960-969.
    • (2002) J Neurochem , vol.80 , pp. 960-969
    • Yuan, J.1    Cord, B.J.2    McCann, U.D.3    Callahan, T.4    Ricaurte, G.A.5
  • 411
    • 0025191891 scopus 로고
    • 3H]methylenedioxyamphetamine: Characterization suggests the presence of a factor responsible for maintaining sequestration
    • 3H]methylenedioxyamphetamine: characterization suggests the presence of a factor responsible for maintaining sequestration. J Neurochem 54:195-204.
    • (1990) J Neurochem , vol.54 , pp. 195-204
    • Zaczek, R.1    Culp, S.2    De Souza, E.B.3
  • 412
    • 0026555524 scopus 로고
    • Synthesis and neurotoxicological evaluation of putative metabolites of the serotonergic neurotoxin 2-(methylamino)-1-[3,4-(methylenedioxy)phenyl]propane [(methylenedioxy)methamphetamine]
    • Zhao Z, Castagnoli N Jr, Ricaurte GA, Steele T, and Martello M (1992) Synthesis and neurotoxicological evaluation of putative metabolites of the serotonergic neurotoxin 2-(methylamino)-1-[3,4-(methylenedioxy)phenyl]propane [(methylenedioxy)methamphetamine]. Chem Res Toxicol 5:89-94.
    • (1992) Chem Res Toxicol , vol.5 , pp. 89-94
    • Zhao, Z.1    Castagnoli N., Jr.2    Ricaurte, G.A.3    Steele, T.4    Martello, M.5
  • 413
    • 0032496695 scopus 로고    scopus 로고
    • Role of brain nitric oxide in (±)3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats
    • Zheng Y and Laverty R (1998) Role of brain nitric oxide in (±)3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats. Brain Res 795:257-263.
    • (1998) Brain Res , vol.795 , pp. 257-263
    • Zheng, Y.1    Laverty, R.2
  • 414
    • 0023047797 scopus 로고
    • A growing industry and menace: Makeshift laboratory's designer drugs
    • Ziporyn T (1986) A growing industry and menace: makeshift laboratory's designer drugs. J Am Med Assoc 256:3061-3063.
    • (1986) J Am Med Assoc , vol.256 , pp. 3061-3063
    • Ziporyn, T.1


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