메뉴 건너뛰기




Volumn 19, Issue 4, 1998, Pages 241-251

Psychological and cardiovascular effects and short-term sequelae of MDMA ('Ecstasy') in MDMA-naive healthy volunteers

Author keywords

'Ecstasy'; Adverse effects; Body temperature; Cardiovascular effects; Entactogen; Hallucinogen; MDMA (3,4 methylenedioxymethamphetamine); Psychological effects; Serotonin; Stimulant; Stroop color naming test

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE;

EID: 0031783570     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(98)00013-X     Document Type: Article
Times cited : (362)

References (54)
  • 1
    • 0024159060 scopus 로고
    • MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons
    • Battaglia G, Yeh SY, De Souza EB (1988): MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons. Pharmacol Biochem Behav 29:269-274
    • (1988) Pharmacol Biochem Behav , vol.29 , pp. 269-274
    • Battaglia, G.1    Yeh, S.Y.2    De Souza, E.B.3
  • 2
    • 0028915821 scopus 로고    scopus 로고
    • Abnormal processing of irrelevant information in attention deficit hyperactivity disorder
    • Carter CS, Krener P, Chaderjian M, Northcutt C, Wolfe V (1996): Abnormal processing of irrelevant information in attention deficit hyperactivity disorder. Psychiatry Res 56:59-70
    • (1996) Psychiatry Res , vol.56 , pp. 59-70
    • Carter, C.S.1    Krener, P.2    Chaderjian, M.3    Northcutt, C.4    Wolfe, V.5
  • 3
    • 0001222519 scopus 로고
    • Personality and the inverted U-relation
    • Corcoran DWJ (1965): Personality and the inverted U-relation. Br J Psychol 56:267-273
    • (1965) Br J Psychol , vol.56 , pp. 267-273
    • Corcoran, D.W.J.1
  • 4
    • 0028335838 scopus 로고
    • Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats
    • Berlin
    • Dafters RI (1994): Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats. Psychopharmacology (Berlin) 114:505-508
    • (1994) Psychopharmacology , vol.114 , pp. 505-508
    • Dafters, R.I.1
  • 5
    • 0030971740 scopus 로고    scopus 로고
    • Ecstasy (MDMA) in recreational users: Self-reported psychological and physiological effects
    • Davison D, Parrott C (1997): Ecstasy (MDMA) in recreational users: Self-reported psychological and physiological effects. Hum Psychopharmacol 12:221-226
    • (1997) Hum Psychopharmacol , vol.12 , pp. 221-226
    • Davison, D.1    Parrott, C.2
  • 6
    • 0001758110 scopus 로고
    • Psychological aspects of altered states of consciousness of the LSD type: Measurements of their basic dimensions and prediction of individual differences
    • Pletscher A, Ladewig D (eds), New York, Parthenon Publishing
    • Dittrich A (1994): Psychological aspects of altered states of consciousness of the LSD type: Measurements of their basic dimensions and prediction of individual differences. In Pletscher A, Ladewig D (eds), 50 years of LSD. Current status and perspectives of hallucinogens. New York, Parthenon Publishing, pp 101-118
    • (1994) 50 Years of LSD. Current Status and Perspectives of Hallucinogens , pp. 101-118
    • Dittrich, A.1
  • 8
    • 0001288904 scopus 로고
    • International study on altered states of consciousness (ISASC). Summary of the results
    • Dittrich A, von Arx S, Staub S (1985): International study on altered states of consciousness (ISASC). Summary of the results. Germ J Psych 9:319-339
    • (1985) Germ J Psych , vol.9 , pp. 319-339
    • Dittrich, A.1    Von Arx, S.2    Staub, S.3
  • 9
    • 0022846114 scopus 로고
    • The psychological and physiological effects of MDMA on normal volunteers
    • Downing J (1986): The psychological and physiological effects of MDMA on normal volunteers. J Psychoactive Drugs 18:335-340
    • (1986) J Psychoactive Drugs , vol.18 , pp. 335-340
    • Downing, J.1
  • 11
    • 0008588933 scopus 로고
    • Factors involved in drug-produced model psychoses
    • Fischer R (1954): Factors involved in drug-produced model psychoses. J Ment Sci 100:623-631
    • (1954) J Ment Sci , vol.100 , pp. 623-631
    • Fischer, R.1
  • 12
    • 0014424064 scopus 로고
    • Personality structure as the main determinant of drug induced (model) psychoses
    • Fischer R, Marks PA, Hill RM, Rockey MA (1968): Personality structure as the main determinant of drug induced (model) psychoses. Nature 218:296-298
    • (1968) Nature , vol.218 , pp. 296-298
    • Fischer, R.1    Marks, P.A.2    Hill, R.M.3    Rockey, M.A.4
  • 14
    • 0025038706 scopus 로고
    • Startle response models of sensorimotor gating and habituation deficits in schizophrenia
    • Geyer MA, Swerdlow NR, Mansbach RS, Braff DL (1990): Startle response models of sensorimotor gating and habituation deficits in schizophrenia. Brain Res Bull 25:485-498
    • (1990) Brain Res Bull , vol.25 , pp. 485-498
    • Geyer, M.A.1    Swerdlow, N.R.2    Mansbach, R.S.3    Braff, D.L.4
  • 15
    • 0031585910 scopus 로고    scopus 로고
    • Ecstasy - La situation en Suisse romande. Composition des saisies, analyse des échantillons biologiques et brève revue de son action pharmacologique et de sa toxicité
    • Giroud C, Augsburger M, Sadeghipour F, Varesio E, Veuthey J-L, Rivier L (1997): Ecstasy - La situation en Suisse romande. Composition des saisies, analyse des échantillons biologiques et brève revue de son action pharmacologique et de sa toxicité. Praxis 86:510-523
    • (1997) Praxis , vol.86 , pp. 510-523
    • Giroud, C.1    Augsburger, M.2    Sadeghipour, F.3    Varesio, E.4    Veuthey, J.-L.5    Rivier, L.6
  • 17
    • 0344325609 scopus 로고    scopus 로고
    • Human experimental neurometabolic and neuropsychological studies with psilocybin, d-methamphetamine and 3,4-methylenedioxyethylamphetamine (MDE)
    • Gouzoulis E, Thelen B, Schreckenberger M, Kovar KA, Spitzer M, Sass H (1997): Human experimental neurometabolic and neuropsychological studies with psilocybin, d-methamphetamine and 3,4-methylenedioxyethylamphetamine (MDE). [Abstract] Pharmacopsychiatry 30:171
    • (1997) Pharmacopsychiatry , vol.30 , pp. 171
    • Gouzoulis, E.1    Thelen, B.2    Schreckenberger, M.3    Kovar, K.A.4    Spitzer, M.5    Sass, H.6
  • 18
  • 19
    • 0029067178 scopus 로고    scopus 로고
    • Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxydmethamphetamine (MDMA of "Ecstasy")
    • Berlin
    • Green AR, Cross AJ, Goodwin GM (1996): Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxydmethamphetamine (MDMA of "Ecstasy"). Psychopharmacology (Berlin) 119:247-260
    • (1996) Psychopharmacology , vol.119 , pp. 247-260
    • Green, A.R.1    Cross, A.J.2    Goodwin, G.M.3
  • 20
    • 0009818929 scopus 로고
    • Using MDMA in psychotherapy
    • Greer G (1985): Using MDMA in psychotherapy. Advances 2:57-62
    • (1985) Advances , vol.2 , pp. 57-62
    • Greer, G.1
  • 21
    • 0022838801 scopus 로고
    • Subjective reports on the effects of MDMA in a clinical setting
    • Greer G, Tolbert P (1986): Subjective reports on the effects of MDMA in a clinical setting. J Psychoactive Drugs 18:319-327
    • (1986) J Psychoactive Drugs , vol.18 , pp. 319-327
    • Greer, G.1    Tolbert, P.2
  • 22
    • 0025259567 scopus 로고
    • Second thoughts on 3,4-methylenedioxymethamphetamine (MDMA) neurotoxicity
    • Grob C, Bravo G, Walsh R (1990): Second thoughts on 3,4-methylenedioxymethamphetamine (MDMA) neurotoxicity. Arch Gen Psychiatry 47:288
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 288
    • Grob, C.1    Bravo, G.2    Walsh, R.3
  • 23
    • 0026696970 scopus 로고
    • The MDMA-neurotoxicity controversy: Implications for clinical research with novel psychoactive drugs
    • Grob CS, Bravo GL, Walsh RN, Liester MB (1992): The MDMA-neurotoxicity controversy: Implications for clinical research with novel psychoactive drugs. J Nerv Ment Dis 180:355-356
    • (1992) J Nerv Ment Dis , vol.180 , pp. 355-356
    • Grob, C.S.1    Bravo, G.L.2    Walsh, R.N.3    Liester, M.B.4
  • 24
    • 13344260012 scopus 로고    scopus 로고
    • Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans - Methodological considerations and preliminary observations
    • Grob CS, Poland RE, Chang L, Ernst T (1996): Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans - Methodological considerations and preliminary observations. Behav Brain Res 73:103-107
    • (1996) Behav Brain Res , vol.73 , pp. 103-107
    • Grob, C.S.1    Poland, R.E.2    Chang, L.3    Ernst, T.4
  • 25
    • 0029846521 scopus 로고    scopus 로고
    • Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS
    • Helmlin HJ, Bracher K, Bourquin D, Vonlanthen D, Brenneisen R (1996): Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS. J Anal Toxicol 20:432-440
    • (1996) J Anal Toxicol , vol.20 , pp. 432-440
    • Helmlin, H.J.1    Bracher, K.2    Bourquin, D.3    Vonlanthen, D.4    Brenneisen, R.5
  • 26
    • 0027413618 scopus 로고
    • Psychological effects of MDE in normal subjects. Are entactogens a new class of psychoactive agents?
    • Hermle L, Spitzer M, Borchardt D, Kovar KA, Gouzoulis E (1993): Psychological effects of MDE in normal subjects. Are entactogens a new class of psychoactive agents? Neuropsychopharmacology 8:171-176
    • (1993) Neuropsychopharmacology , vol.8 , pp. 171-176
    • Hermle, L.1    Spitzer, M.2    Borchardt, D.3    Kovar, K.A.4    Gouzoulis, E.5
  • 27
    • 0343354071 scopus 로고
    • Arylalkanamine-induced effects in normal volunteers: On the significance of research in hallucinogenic agents for psychiatry
    • Pletscher A, Ladewig D (eds), New York, London, The Parthenon Publishing Group
    • Hermle L, Spitzer M, Gouzoulis E (1994): Arylalkanamine-induced effects in normal volunteers: On the significance of research in hallucinogenic agents for psychiatry. In Pletscher A, Ladewig D (eds), 50 Years of LSD. Current status and perspectives of hallucinogens. New York, London, The Parthenon Publishing Group, pp 87-99
    • (1994) 50 Years of LSD. Current Status and Perspectives of Hallucinogens , pp. 87-99
    • Hermle, L.1    Spitzer, M.2    Gouzoulis, E.3
  • 28
    • 0024383159 scopus 로고
    • 3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys
    • Insel TR, Battaglia G, Johannessen JN, Marra S, De Souza EB (1989): 3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys. J Pharmacol Exp Ther 249:713-720
    • (1989) J Pharmacol Exp Ther , vol.249 , pp. 713-720
    • Insel, T.R.1    Battaglia, G.2    Johannessen, J.N.3    Marra, S.4    De Souza, E.B.5
  • 30
    • 0022911226 scopus 로고
    • Effects of the enantiomeres of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices
    • Johnson MP, Hoffman AJ, Nichols DE (1986): Effects of the enantiomeres of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices. Eur J Pharmacol 132:269-276
    • (1986) Eur J Pharmacol , vol.132 , pp. 269-276
    • Johnson, M.P.1    Hoffman, A.J.2    De Nichols3
  • 31
    • 0029816194 scopus 로고    scopus 로고
    • Das neurospychiatrische Risiko von 3,4-Methylendioxymethamphetamin ("Ecstasy")
    • Kemmerling K, Haller R, Hinterhuber H (1996): Das neurospychiatrische Risiko von 3,4-Methylendioxymethamphetamin ("Ecstasy"). Neuropsychiatrie 10:94-102
    • (1996) Neuropsychiatrie , vol.10 , pp. 94-102
    • Kemmerling, K.1    Haller, R.2    Hinterhuber, H.3
  • 32
    • 0026716102 scopus 로고
    • Phenomenology and sequelae of 3,4-methylendioxymetamphetamine use
    • Liester MB, Grob CS, Bravo G, Walsh RN (1992): Phenomenology and sequelae of 3,4-methylendioxymetamphetamine use. J Nerv Ment Dis 180:345-352
    • (1992) J Nerv Ment Dis , vol.180 , pp. 345-352
    • Liester, M.B.1    Grob, C.S.2    Bravo, G.3    Walsh, R.N.4
  • 33
    • 0026132381 scopus 로고
    • Half a century of research on the Stroop effect: An integrative review
    • MacLeod CM (1991): Half a century of research on the Stroop effect: An integrative review. Psychol Bull 109:163-203
    • (1991) Psychol Bull , vol.109 , pp. 163-203
    • MacLeod, C.M.1
  • 34
    • 0025863667 scopus 로고
    • Lasting neuropsychiatric sequelae of (±) methylenedioxymeth-amphetamine ("ecstasy") in recreational users
    • McCann UD, Ricaurte GA (1991): Lasting neuropsychiatric sequelae of (±) methylenedioxymeth-amphetamine ("ecstasy") in recreational users. J Clin Psychopharmacol 11:302-305
    • (1991) J Clin Psychopharmacol , vol.11 , pp. 302-305
    • McCann, U.D.1    Ricaurte, G.A.2
  • 35
    • 0027008253 scopus 로고
    • MDMA ("ecstasy") and panic disorder: Induction by a single dose
    • McCann UD, Ricaurte GA (1992): MDMA ("ecstasy") and panic disorder: induction by a single dose. Biol Psychiatry 32:950-953
    • (1992) Biol Psychiatry , vol.32 , pp. 950-953
    • McCann, U.D.1    Ricaurte, G.A.2
  • 36
    • 0013578406 scopus 로고
    • Disorder of attention and perception in early schizophrenia
    • McGhie A, Chapman J (1961): Disorder of attention and perception in early schizophrenia. Br J Med Psychol 34:102-116
    • (1961) Br J Med Psychol , vol.34 , pp. 102-116
    • McGhie, A.1    Chapman, J.2
  • 37
    • 0022838197 scopus 로고
    • Differences between the mechanism of action of MDMA, MBDB, and the classical hallucinogens. Identification of a new therapeutic class: Entactogens
    • Nichols DE (1986): Differences between the mechanism of action of MDMA, MBDB, and the classical hallucinogens. Identification of a new therapeutic class: Entactogens. J Psychoactive Drugs 18:305-313
    • (1986) J Psychoactive Drugs , vol.18 , pp. 305-313
    • Nichols, D.E.1
  • 38
    • 0026674432 scopus 로고
    • MDMA (Ecstasy) precipitation of panic disorder
    • Pallanti S, Mazzi D (1992): MDMA (Ecstasy) precipitation of panic disorder. Biol Psychiatry 32:91-95
    • (1992) Biol Psychiatry , vol.32 , pp. 91-95
    • Pallanti, S.1    Mazzi, D.2
  • 39
    • 0024241851 scopus 로고
    • Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users
    • Peroutka SJ, Newman H, Harris H (1988): Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. Neuropsychopharmacology 1:273-277
    • (1988) Neuropsychopharmacology , vol.1 , pp. 273-277
    • Peroutka, S.J.1    Newman, H.2    Harris, H.3
  • 40
    • 0022357597 scopus 로고
    • Hallucinogenic amphetamines selectively destroy brain serotonin nerve terminals
    • Ricaurte G, Bryan G, Strauss L, Seiden L, Schuster C (1985): Hallucinogenic amphetamines selectively destroy brain serotonin nerve terminals. Science 229:1505-1506
    • (1985) Science , vol.229 , pp. 1505-1506
    • Ricaurte, G.1    Bryan, G.2    Strauss, L.3    Seiden, L.4    Schuster, C.5
  • 41
    • 0023902232 scopus 로고
    • Toxic effects of MDMA on central serotonergic neurons in the primate: Importance of route and frequency of drug administration
    • Ricaurte GA, DeLanney LE, Irwin I, Langston JW (1988): Toxic effects of MDMA on central serotonergic neurons in the primate: Importance of route and frequency of drug administration. Brain Res 446:165-168
    • (1988) Brain Res , vol.446 , pp. 165-168
    • Ricaurte, G.A.1    DeLanney, L.E.2    Irwin, I.3    Langston, J.W.4
  • 42
    • 0028307423 scopus 로고
    • A new pharmophoric model for 5-HT reuptake-inhibitors: Differentiation of amphetamine analogues
    • Rupp A, Kovar KA, Beuerle G, Ruf C, Folkers G (1994): A new pharmophoric model for 5-HT reuptake-inhibitors: Differentiation of amphetamine analogues. Pharm Acta Helv 68:235-244
    • (1994) Pharm Acta Helv , vol.68 , pp. 235-244
    • Rupp, A.1    Kovar, K.A.2    Beuerle, G.3    Ruf, C.4    Folkers, G.5
  • 44
    • 0023163857 scopus 로고
    • Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine
    • Schmidt CJ (1987): Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. J Pharmacol Exp Ther 240:240-247
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 240-247
    • Schmidt, C.J.1
  • 46
    • 0022839628 scopus 로고
    • The background and chemistry of MDMA
    • Shulgin AT (1986): The background and chemistry of MDMA. J Psychoactive Drugs 18:291-304
    • (1986) J Psychoactive Drugs , vol.18 , pp. 291-304
    • Shulgin, A.T.1
  • 47
    • 0026710950 scopus 로고
    • Recreational MDMA use in Sydney: A profile of "Ecstacy" users and their experiences with the drug
    • Solowij N, Hall W, Lee N (1992): Recreational MDMA use in Sydney: A profile of "Ecstacy" users and their experiences with the drug. Br J Addict 87:1161-1172
    • (1992) Br J Addict , vol.87 , pp. 1161-1172
    • Solowij, N.1    Hall, W.2    Lee, N.3
  • 48
    • 0028292728 scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): Pharmacology and toxicology in animals and humans
    • Steele TD, McCann UD, Ricaurte GA (1994): 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): Pharmacology and toxicology in animals and humans. Addiction 89:539-551
    • (1994) Addiction , vol.89 , pp. 539-551
    • Steele, T.D.1    McCann, U.D.2    Ricaurte, G.A.3
  • 49
    • 0028962202 scopus 로고
    • Hallucinogenic drugs in psychiatric research and treatment
    • Strassman RJ (1995): Hallucinogenic drugs in psychiatric research and treatment. J Nerv Ment Dis 183:127-138
    • (1995) J Nerv Ment Dis , vol.183 , pp. 127-138
    • Strassman, R.J.1
  • 50
    • 57049145197 scopus 로고
    • Studies of interference in serial and verbal reactions
    • Stroop JR (1935): Studies of interference in serial and verbal reactions. J Exp Psychol 18:643
    • (1935) J Exp Psychol , vol.18 , pp. 643
    • Stroop, J.R.1
  • 51
    • 0345620100 scopus 로고    scopus 로고
    • Effects of high amphetamine doses on mood and cerebral glucose metabolism in normals using positron emission tomography (PET)
    • in press
    • Vollenweider FX, Antonini A, Leenders KL, Mathys K, Angst J (1997a): Effects of high amphetamine doses on mood and cerebral glucose metabolism in normals using positron emission tomography (PET). Psychiatry Res: Neuroimaging, in press
    • (1997) Psychiatry Res: Neuroimaging
    • Vollenweider, F.X.1    Antonini, A.2    Leenders, K.L.3    Mathys, K.4    Angst, J.5
  • 52
    • 0030916849 scopus 로고    scopus 로고
    • Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis
    • Vollenweider FX, Leenders KL, Scharfetter C, Maguire P, Stadelmann O, Angst J (1997b): Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis. Neuropsychopharmacology 16:357-372
    • (1997) Neuropsychopharmacology , vol.16 , pp. 357-372
    • Vollenweider, F.X.1    Leenders, K.L.2    Scharfetter, C.3    Maguire, P.4    Stadelmann, O.5    Angst, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.