2,5-bis-(glutathion-S-yl)-α-methyldopamine, a putative metabolite of (±)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations

European Journal of Pharmacology

Volumn 323, Issue 2-3, 1997, Pages 173-180

  Miller, R Timothy ^a,b   Lau, Serrine S ^a   Monks, Terrence J ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

methyldopamine; 5 HT (5 hydroxytryptamine, serotonin); Glutathione; MDA (3,4 Methylenedioxyamphetamine); MDMA (3,4 Methylenedioxymethamphetamine); Neurotoxicity

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPHA METHYLDOPAMINE; DOPAMINE DERIVATIVE; DRUG METABOLITE; GLUTATHIONE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DRUG CONJUGATION; HIPPOCAMPUS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN BRAIN LEVEL; SUBCUTANEOUS DRUG ADMINISTRATION;

3,4-METHYLENEDIOXYAMPHETAMINE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CEREBRAL CORTEX; CORPUS STRIATUM; DEOXYEPINEPHRINE; DEPRESSION, CHEMICAL; GLUTATHIONE; HIPPOCAMPUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN AGENTS;

EID: 0030951385     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00044-7     Document Type: Article

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