메뉴 건너뛰기




Volumn 144, Issue 1, 1999, Pages 67-76

Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat

Author keywords

Citalopram binding; Cognition; DNMTP; Locomotor activity; MDMA; Neurotoxicity; Paw reaching; Temperature 5 HT

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; CITALOPRAM; NEUROTOXIN;

EID: 0032976911     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050978     Document Type: Article
Times cited : (82)

References (41)
  • 1
    • 0024158068 scopus 로고
    • What is the nature of the role of the serotonergic nervous system in learning and memory: Prospects for development of an effective treatment strategy for senile dementia
    • Altman HJ, Normile HJ (1988) What is the nature of the role of the serotonergic nervous system in learning and memory: prospects for development of an effective treatment strategy for senile dementia. Neurobiol Ageing 9:627-638
    • (1988) Neurobiol Ageing , vol.9 , pp. 627-638
    • Altman, H.J.1    Normile, H.J.2
  • 2
    • 0024159060 scopus 로고
    • MDMA induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurones
    • Battaglia G, Yeh SY, De Souza EB (1987a) MDMA induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurones. Pharmacol Biochem Behav 29:269-274
    • (1987) Pharmacol Biochem Behav , vol.29 , pp. 269-274
    • Battaglia, G.1    Yeh, S.Y.2    De Souza, E.B.3
  • 4
    • 0029112473 scopus 로고
    • The hyperthermic and neurotoxic effects of "Ecstasy" (MDMA) and 3,4-methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype
    • Colado MI, Williams JL, Green AR (1995) The hyperthermic and neurotoxic effects of "Ecstasy" (MDMA) and 3,4-methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype. Br J Pharmacol 115:1281-1289
    • (1995) Br J Pharmacol , vol.115 , pp. 1281-1289
    • Colado, M.I.1    Williams, J.L.2    Green, A.R.3
  • 5
    • 0028335838 scopus 로고
    • Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats
    • Dafters RI (1994) Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats. Psychopharmacology 114:505-508
    • (1994) Psychopharmacology , vol.114 , pp. 505-508
    • Dafters, R.I.1
  • 6
    • 0028858685 scopus 로고
    • Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing
    • Dafters RI (1995) Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing. Physiol Behav 58:877-882
    • (1995) Physiol Behav , vol.58 , pp. 877-882
    • Dafters, R.I.1
  • 7
    • 0031822039 scopus 로고    scopus 로고
    • Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy")
    • Dafters RI, Lynch E (1998) Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy"). Psychopharmacology 138:207-212
    • (1998) Psychopharmacology , vol.138 , pp. 207-212
    • Dafters, R.I.1    Lynch, E.2
  • 8
    • 0029125154 scopus 로고
    • Reorganisation of ascending 5-HT axon projections in animals previously exposed to the recreational drug (±)-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Fischer C, Hatzidimitriou G, Wlos G, Katz J, Ricaurte G (1995) Reorganisation of ascending 5-HT axon projections in animals previously exposed to the recreational drug (±)-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). J Neurosci 15:5476-5485
    • (1995) J Neurosci , vol.15 , pp. 5476-5485
    • Fischer, C.1    Hatzidimitriou, G.2    Wlos, G.3    Katz, J.4    Ricaurte, G.5
  • 9
    • 0029077738 scopus 로고
    • Acute effects of methylenedioxymethamphetamine (MDMA) on several complex brain functions in monkeys
    • Frederick DL, Gillam MP, Allen RR, Paule MG (1995a) Acute effects of methylenedioxymethamphetamine (MDMA) on several complex brain functions in monkeys. Pharmacol Biochem Behav 51:301-307
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 301-307
    • Frederick, D.L.1    Gillam, M.P.2    Allen, R.R.3    Paule, M.G.4
  • 10
    • 0028874867 scopus 로고
    • Behavioural and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatment in Rhesus monkeys
    • Frederick DL, Ali SF, Slikker W Jr, Gillam MP, Allen RR, Paule MG (1995b) Behavioural and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatment in Rhesus monkeys. Neurotoxicol Teratol 17:531-543
    • (1995) Neurotoxicol Teratol , vol.17 , pp. 531-543
    • Frederick, D.L.1    Ali, S.F.2    Slikker W., Jr.3    Gillam, M.P.4    Allen, R.R.5    Paule, M.G.6
  • 11
    • 0024366246 scopus 로고
    • The effect of optical isomers of 3,4-methylenedioxymethamphetamine (MDMA) on stereotyped behaviours in the rat
    • Hiramatasu MT, Kameyama NT, Meada Y, Cho K (1988) The effect of optical isomers of 3,4-methylenedioxymethamphetamine (MDMA) on stereotyped behaviours in the rat. Pharmacol Biochem Behav 33:343-347
    • (1988) Pharmacol Biochem Behav , vol.33 , pp. 343-347
    • Hiramatasu, M.T.1    Kameyama, N.T.2    Meada, Y.3    Cho, K.4
  • 12
    • 0017086367 scopus 로고
    • An animal model for studying central serotonergic synapses
    • Jacobs BL (1976) An animal model for studying central serotonergic synapses. Life Sci 19:777-786
    • (1976) Life Sci , vol.19 , pp. 777-786
    • Jacobs, B.L.1
  • 13
    • 0027336039 scopus 로고
    • 1A and 5-HT transporter binding sites in rat cortex and hippocampus following cholinergic and serotonergic lesions
    • 1A and 5-HT transporter binding sites in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain Res 612:326-329
    • (1993) Brain Res , vol.612 , pp. 326-329
    • Lawrence, J.A.1    Olverman, H.J.2    Shirikawa, K.3    Kelly, J.S.4    Butcher, S.P.5
  • 14
    • 0027520720 scopus 로고
    • MDMA and memory: The acute and chronic effects of MDMA in pigeons performing under a delayed-matching-to-sample procedure
    • LeSage M, Clark R, Poling A (1993) MDMA and memory: the acute and chronic effects of MDMA in pigeons performing under a delayed-matching-to-sample procedure. Psychopharmacology 110:327-332
    • (1993) Psychopharmacology , vol.110 , pp. 327-332
    • Lesage, M.1    Clark, R.2    Poling, A.3
  • 15
    • 0032125256 scopus 로고    scopus 로고
    • Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature
    • Malberg JE, Seiden LS (1998) Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature. J Neurosci 18:5086-5094
    • (1998) J Neurosci , vol.18 , pp. 5086-5094
    • Malberg, J.E.1    Seiden, L.S.2
  • 16
    • 0029009704 scopus 로고
    • Behavioural assessment of endothelin-1 induced middle cerebral artery occlusion in the rat
    • Marston HM, Faber ESL, Crawford JH, Butcher SP, Sharkey JS (1995) Behavioural assessment of endothelin-1 induced middle cerebral artery occlusion in the rat. Neuroreport 6: 1067-1071
    • (1995) Neuroreport , vol.6 , pp. 1067-1071
    • Marston, H.M.1    Faber, E.S.L.2    Crawford, J.H.3    Butcher, S.P.4    Sharkey, J.S.5
  • 17
    • 0032585201 scopus 로고    scopus 로고
    • Positron emission tomography evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurones in human beings
    • McCann UD, Szabo Z, Scheffel U, Dannals RF, Ricaurte GA (1998) Positron emission tomography evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurones in human beings. Lancet 352:1433-1437
    • (1998) Lancet , vol.352 , pp. 1433-1437
    • McCann, U.D.1    Szabo, Z.2    Scheffel, U.3    Dannals, R.F.4    Ricaurte, G.A.5
  • 18
    • 21344485887 scopus 로고
    • MDMA: Its history and pharmacology
    • McDowell DM, Kleber HD (1994) MDMA: its history and pharmacology. Psychiatr Ann 24:127-130
    • (1994) Psychiatr Ann , vol.24 , pp. 127-130
    • McDowell, D.M.1    Kleber, H.D.2
  • 19
    • 0029142917 scopus 로고
    • Some behavioural and neurochemical aspects of subacute (±)-3,4-methylenedioxymethamphetamine administration in rats
    • McNamara MG, Kelly JP, Leonard BE (1995) Some behavioural and neurochemical aspects of subacute (±)-3,4-methylenedioxymethamphetamine administration in rats. Pharmacol Biochem Behav 52:479-484
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 479-484
    • McNamara, M.G.1    Kelly, J.P.2    Leonard, B.E.3
  • 21
    • 0026326549 scopus 로고
    • Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: Effect of dopamine uptake inhibitors
    • Nash JF, Brodkin J (1991) Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors. J Pharmacol Exp Ther 259: 820-825
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 820-825
    • Nash, J.F.1    Brodkin, J.2
  • 22
    • 0023898060 scopus 로고
    • Elevation of serum prolactin and corticosterone concentrations in the rat after administration of 3,4-methylenedioxymethamphetamine
    • Nash JF, Meltzer HY, Gudelsky GA (1988) Elevation of serum prolactin and corticosterone concentrations in the rat after administration of 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 245:373-379
    • (1988) J Pharmacol Exp Ther , vol.245 , pp. 373-379
    • Nash, J.F.1    Meltzer, H.Y.2    Gudelsky, G.A.3
  • 23
    • 0031952270 scopus 로고    scopus 로고
    • Emotional and cognitive effects of MDMA ("ecstasy"): The psychological perspective
    • Parrott AC (1998) Emotional and cognitive effects of MDMA ("ecstasy"): the psychological perspective. J Psychopharmacol 12:99-100
    • (1998) J Psychopharmacol , vol.12 , pp. 99-100
    • Parrott, A.C.1
  • 24
    • 0031677797 scopus 로고    scopus 로고
    • Ecstasy (MDMA) effects upon mood and cognition: Before, during and after Saturday night dance
    • Parrott AC, Lasky J (1998) Ecstasy (MDMA) effects upon mood and cognition: before, during and after Saturday night dance. Psychopharmacology 139:261-268
    • (1998) Psychopharmacology , vol.139 , pp. 261-268
    • Parrott, A.C.1    Lasky, J.2
  • 25
    • 0026731608 scopus 로고
    • The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity
    • Paulus MP, Geyer MA (1992) The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity. Neuropsychopharmacology 7:15-31
    • (1992) Neuropsychopharmacology , vol.7 , pp. 15-31
    • Paulus, M.P.1    Geyer, M.A.2
  • 26
    • 0023616493 scopus 로고
    • Incidence of recreational use of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") on an undergraduate campus
    • Peroutka SJ (1987) Incidence of recreational use of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") on an undergraduate campus. N Engl J Med 317:1542-1543
    • (1987) N Engl J Med , vol.317 , pp. 1542-1543
    • Peroutka, S.J.1
  • 27
    • 0026644079 scopus 로고
    • Ecstasy-fuelled "rave" parties become dances of death for English youths
    • Randall T (1992) Ecstasy-fuelled "rave" parties become dances of death for English youths. JAMA 268:1505-1506
    • (1992) JAMA , vol.268 , pp. 1505-1506
    • Randall, T.1
  • 28
    • 0026612759 scopus 로고
    • Lasting effects of (±)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurones in non-human primates: Neurochemical observations
    • Ricaurte GA, Martello AL, Katz JL, Martello MB (1992) Lasting effects of (±)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurones in non-human primates: neurochemical observations. J Pharmacol Exp Ther 261:616-622
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 616-622
    • Ricaurte, G.A.1    Martello, A.L.2    Katz, J.L.3    Martello, M.B.4
  • 30
    • 0023081892 scopus 로고
    • Some limitations of indices derived from signal detection theory: Evaluation of an alternative index for measuring bias in memory tasks
    • Sahgal A (1987) Some limitations of indices derived from signal detection theory: evaluation of an alternative index for measuring bias in memory tasks. Psychopharmacology 91:517-520
    • (1987) Psychopharmacology , vol.91 , pp. 517-520
    • Sahgal, A.1
  • 31
  • 33
    • 0023163857 scopus 로고
    • Neurotoxicity of the psychedelic amphetamine, methylenedioxyamphetamine
    • Schmidt CJ (1987) Neurotoxicity of the psychedelic amphetamine, methylenedioxyamphetamine. J Pharmacol Exp Ther 240:1-7
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 1-7
    • Schmidt, C.J.1
  • 34
    • 0023109989 scopus 로고
    • In vitro and in vivo neurochemical effects of methylenedioxyamphetamine on striatal monoaminergic systems in the brain
    • Schmidt CJ, Levin AL and Lovenberg W (1986) In vitro and in vivo neurochemical effects of methylenedioxyamphetamine on striatal monoaminergic systems in the brain. Biochem Pharmacol 36:747-755
    • (1986) Biochem Pharmacol , vol.36 , pp. 747-755
    • Schmidt, C.J.1    Levin, A.L.2    Lovenberg, W.3
  • 35
    • 0025880607 scopus 로고
    • Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy")
    • Sharkey J, McBean DE, Kelly PAT (1991) Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy"). Psychopharmacology 105:113-118
    • (1991) Psychopharmacology , vol.105 , pp. 113-118
    • Sharkey, J.1    McBean, D.E.2    Kelly, P.A.T.3
  • 36
    • 0018165067 scopus 로고
    • Specificity of a rat behavioural model for serotonin receptor activation
    • Solivier RS, Drust EG, Conner JD (1978) Specificity of a rat behavioural model for serotonin receptor activation. J Pharmacol Exp Ther 206:339-347
    • (1978) J Pharmacol Exp Ther , vol.206 , pp. 339-347
    • Solivier, R.S.1    Drust, E.G.2    Conner, J.D.3
  • 37
    • 0031749512 scopus 로고    scopus 로고
    • An integrated hypothesis for the serotonergic loss induced by 3,4-methylenedioxymethamphetamine
    • Sprague JE, Everman SL, Nichols DE (1998) An integrated hypothesis for the serotonergic loss induced by 3,4-methylenedioxymethamphetamine. Neurotoxicology 19:427-441
    • (1998) Neurotoxicology , vol.19 , pp. 427-441
    • Sprague, J.E.1    Everman, S.L.2    Nichols, D.E.3
  • 38
    • 0022911033 scopus 로고
    • The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the brain
    • Stone DM, Stahl DC, Hanson GR, Gibb JW (1986) The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the brain. Eur J Pharmacol 128:41-48
    • (1986) Eur J Pharmacol , vol.128 , pp. 41-48
    • Stone, D.M.1    Stahl, D.C.2    Hanson, G.R.3    Gibb, J.W.4
  • 39
    • 0023484528 scopus 로고
    • Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat
    • Stone DM, Merchant KM, Hanson GR, Gibb JW (1987) Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat. Neuropharmacology 26:1677-1683
    • (1987) Neuropharmacology , vol.26 , pp. 1677-1683
    • Stone, D.M.1    Merchant, K.M.2    Hanson, G.R.3    Gibb, J.W.4
  • 40
    • 0023185050 scopus 로고
    • Suppression of serotonin-dependent cerebral activation: A possible mechanism of action of some psychotomimetic drugs
    • Vanderwolf CH (1987) Suppression of serotonin-dependent cerebral activation: a possible mechanism of action of some psychotomimetic drugs. Brain Res 414:109-118
    • (1987) Brain Res , vol.414 , pp. 109-118
    • Vanderwolf, C.H.1
  • 41
    • 0023870334 scopus 로고
    • The acute effects of methylenedioxyamphetamine on dopamine release in the awake behaving rat
    • Yamamoto BK, Spanos LJ (1989) The acute effects of methylenedioxyamphetamine on dopamine release in the awake behaving rat. Eur J Pharmacol 148:195-203
    • (1989) Eur J Pharmacol , vol.148 , pp. 195-203
    • Yamamoto, B.K.1    Spanos, L.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.