Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR

British Journal of Pharmacology

Volumn 124, Issue 3, 1998, Pages 479-484

  Colado, M I ^a   Granados, R ^a   O'Shea, E ^a   Esteban, B ^a   Green, A R ^b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b Astra Arcus   (United Kingdom)

Author keywords

3,4 methylenedioxymethamphetamine; 5 hydroxytryptamine; AR R15896AR; Clomethiazole; Ecstasy; Hypothermia; Neurodegeneration; Neuroprotection; NMDA antagonists

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 5 HYDROXYINDOLEACETIC ACID; AR R 15896 AR; CLOMETHIAZOLE; GLUTAMIC ACID; LANICEMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; PAROXETINE; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BODY TEMPERATURE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; CRANIAL NERVE; HIPPOCAMPUS; HYPOTHERMIA; MALE; NERVE DEGENERATION; NERVE ENDING; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECTUM TEMPERATURE;

ANIMALS; BODY TEMPERATURE; BRAIN CHEMISTRY; CHLORMETHIAZOLE; EXCITATORY AMINO ACID ANTAGONISTS; FEVER; HYDROXYINDOLEACETIC ACID; MALE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PAROXETINE; PYRIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SEROTONIN; SEROTONIN UPTAKE INHIBITORS;

EID: 0031746324     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701859     Document Type: Article

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