메뉴 건너뛰기




Volumn 30, Issue 3, 1999, Pages 250-263

Serotonin, cerebral blood flow, and cerebral metabolic rate in geriatric major depression and normal aging

Author keywords

Aging; Cerebral blood flow; Cerebral metabolic rate; Major depressive disorder; Serotonin

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; FLUOXETINE; IMIPRAMINE; NORTRIPTYLINE; PAROXETINE; RADIOLIGAND; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRYPTOPHAN;

EID: 0032737167     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(99)00019-3     Document Type: Review
Times cited : (42)

References (160)
  • 4
    • 0031732769 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor efficacy in severe and melancholic depression
    • Amsterdam J.D. Selective serotonin reuptake inhibitor efficacy in severe and melancholic depression. J. Psychopharmacol. 12:1998;S99-S111.
    • (1998) J. Psychopharmacol. , vol.12
    • Amsterdam, J.D.1
  • 5
    • 0028019316 scopus 로고
    • The efficacy of selective serotonin reuptake inhibitors in depression: A meta-analysis of studies against tricyclic antidepressants
    • Anderson I.M., Tomenson B.M. The efficacy of selective serotonin reuptake inhibitors in depression: a meta-analysis of studies against tricyclic antidepressants. J. Psychopharmacol. 8:1994;238-249.
    • (1994) J. Psychopharmacol. , vol.8 , pp. 238-249
    • Anderson, I.M.1    Tomenson, B.M.2
  • 7
    • 0027301788 scopus 로고
    • Effect of aging in human cortical pre- And postsynaptic serotonin binding sites
    • Arranz B., Eriksson A., Mellerup E., Plenge P., Marcusson J. Effect of aging in human cortical pre- and postsynaptic serotonin binding sites. Brain Res. 620:1993;163-166.
    • (1993) Brain Res. , vol.620 , pp. 163-166
    • Arranz, B.1    Eriksson, A.2    Mellerup, E.3    Plenge, P.4    Marcusson, J.5
  • 8
    • 0027340522 scopus 로고
    • 3H]-paroxetine binding in rat brain: Effect of imipramine and tetrahydroacridine
    • 3H ]-paroxetine binding in rat brain: effect of imipramine and tetrahydroacridine Life Sci. 52:1993;1767-1775.
    • (1993) Life Sci. , vol.52 , pp. 1767-1775
    • Arora, R.C.1    Gulati, A.2    Crayton, J.W.3
  • 9
    • 0025934933 scopus 로고
    • Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons
    • Aston-Jones G., Akaoka H., Charlety P., Chouvet G. Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons. J. Neurosci. 11:1991;760-769.
    • (1991) J. Neurosci. , vol.11 , pp. 760-769
    • Aston-Jones, G.1    Akaoka, H.2    Charlety, P.3    Chouvet, G.4
  • 13
    • 0026640757 scopus 로고
    • The anatomy of melancholia - Focal abnormalities of cerebral blood flow in major depression
    • Bench C.J., Friston K., Brown R.G., Scott L.C., Frackowiak R.S., Dolan R.J. The anatomy of melancholia - focal abnormalities of cerebral blood flow in major depression. Psychol. Med. 22:1992;607-615.
    • (1992) Psychol. Med. , vol.22 , pp. 607-615
    • Bench, C.J.1    Friston, K.2    Brown, R.G.3    Scott, L.C.4    Frackowiak, R.S.5    Dolan, R.J.6
  • 18
    • 0011315634 scopus 로고
    • Serotonin and the cerebral circulation
    • in: J.W. Phillis (Ed.), CRC Press, Boca Raton, FL
    • G. Bonvento, P. Lacombe, Serotonin and the cerebral circulation, in: J.W. Phillis (Ed.), The Regulation of Cerebral Blood Flow, CRC Press, Boca Raton, FL, 1994, pp. 97-112.
    • (1994) The Regulation of Cerebral Blood Flow , pp. 97-112
    • Bonvento, G.1    Lacombe, P.2
  • 19
  • 20
    • 0023708149 scopus 로고
    • Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment
    • Brunello N., Riva M., Rovescalli A., Galimberti R., Racagni G. Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment. Pharmacol. Toxicol. 63:1988;150-155.
    • (1988) Pharmacol. Toxicol. , vol.63 , pp. 150-155
    • Brunello, N.1    Riva, M.2    Rovescalli, A.3    Galimberti, R.4    Racagni, G.5
  • 22
    • 0032191007 scopus 로고    scopus 로고
    • Assessment of serotonergic function in major depression using D-fenfluramine: Relation to clinical variables and antidepressant response
    • Cleare A.J., Murray R.M., O'Keane V. Assessment of serotonergic function in major depression using D-fenfluramine: relation to clinical variables and antidepressant response. Biol. Psychiatry. 44:1998;555-561.
    • (1998) Biol. Psychiatry , vol.44 , pp. 555-561
    • Cleare, A.J.1    Murray, R.M.2    O'Keane, V.3
  • 23
    • 0025141318 scopus 로고
    • Subcortical hyperintensity on magnetic resonance imaging: A comparison of normal and depressed elderly subjects
    • Coffey C.E., Figiel G.S., Djang W.T., Weiner R.D. Subcortical hyperintensity on magnetic resonance imaging: a comparison of normal and depressed elderly subjects. Am. J. Psychiatry. 147:1990;187-189.
    • (1990) Am. J. Psychiatry , vol.147 , pp. 187-189
    • Coffey, C.E.1    Figiel, G.S.2    Djang, W.T.3    Weiner, R.D.4
  • 24
    • 0030293754 scopus 로고    scopus 로고
    • Serotonin in the regulation of brain microcirculation
    • Cohen Z., Bonvento G., Lacombe P., Hamel E. Serotonin in the regulation of brain microcirculation. Prog. Neurobiol. 50:1996;335-362.
    • (1996) Prog. Neurobiol. , vol.50 , pp. 335-362
    • Cohen, Z.1    Bonvento, G.2    Lacombe, P.3    Hamel, E.4
  • 26
    • 0025355983 scopus 로고
    • Cerebrovascular nerves in old rats show reduced accumulation of 5-hydroxytryptamine and loss of nerve fibers
    • Cowen T., Thrasivoulou C. Cerebrovascular nerves in old rats show reduced accumulation of 5-hydroxytryptamine and loss of nerve fibers. Brain Res. 513:1990;237-243.
    • (1990) Brain Res. , vol.513 , pp. 237-243
    • Cowen, T.1    Thrasivoulou, C.2
  • 27
    • 0023829258 scopus 로고
    • Influence of ascending serotonergic pathways on glucose use in the conscious rat brain: II. Effects of electrical stimulation of the rostral raphe nuclei
    • Cudennec A., Duverger D., Serrano A., Scatton B., MacKenzie E.T. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain: II. Effects of electrical stimulation of the rostral raphe nuclei. Brain Res. 444:1988;227-246.
    • (1988) Brain Res. , vol.444 , pp. 227-246
    • Cudennec, A.1    Duverger, D.2    Serrano, A.3    Scatton, B.4    MacKenzie, E.T.5
  • 28
    • 0022448068 scopus 로고
    • Citalopram: Clinical effect profile in comparison with clomipramine. A controlled multicenter study
    • Danish University Antidepressant Group Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicenter study. Psychopharmacology. 90:1986;131-138.
    • (1986) Psychopharmacology , vol.90 , pp. 131-138
    • Danish University Antidepressant Group1
  • 29
    • 0025217229 scopus 로고
    • A selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study
    • Danish University Antidepressant Group A selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study. J. Affective Disord. 18:1990;289-299.
    • (1990) J. Affective Disord. , vol.18 , pp. 289-299
    • Danish University Antidepressant Group1
  • 30
    • 0026005750 scopus 로고
    • Rapid serotonin depletion as a provocative challenge test for patients with major depression: Relevance to antidepressant action and the neurobiology of depression
    • Delgado P.L., Price L.H., Miller H.L., Salomon R.M., Licinio J., Krystal J.H., Heninger G.R., Charney D.S. Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression. Psychopharmacol. Bull. 27:1991;321-330.
    • (1991) Psychopharmacol. Bull. , vol.27 , pp. 321-330
    • Delgado, P.L.1    Price, L.H.2    Miller, H.L.3    Salomon, R.M.4    Licinio, J.5    Krystal, J.H.6    Heninger, G.R.7    Charney, D.S.8
  • 33
    • 0031969731 scopus 로고    scopus 로고
    • Functional neuroimaging studies of depression: The anatomy of melancholia
    • Drevets W.C. Functional neuroimaging studies of depression: the anatomy of melancholia. Annu. Rev. Med. 49:1998;341-361.
    • (1998) Annu. Rev. Med. , vol.49 , pp. 341-361
    • Drevets, W.C.1
  • 36
    • 84937168898 scopus 로고
    • Risk factors in stroke: A statement for physicians by the subcommittee on risk factors and stroke of the Stroke Council
    • Dyken M.L., Wolf P.A., Barnett H.J.M. Risk factors in stroke: a statement for physicians by the subcommittee on risk factors and stroke of the Stroke Council. Stroke. 15:1984;1105-1111.
    • (1984) Stroke , vol.15 , pp. 1105-1111
    • Dyken, M.L.1    Wolf, P.A.2    Barnett, H.J.M.3
  • 37
  • 38
    • 0345642933 scopus 로고
    • Cerebral circulation during aging
    • in: J.W. Phillis (Ed.), CRC Press, Boca Raton, FL
    • F. Faraci, Cerebral circulation during aging, in: J.W. Phillis (Ed.), The Regulation of Cerebral Blood Flow, CRC Press, Boca Raton, FL, 1994, pp. 341-352.
    • (1994) The Regulation of Cerebral Blood Flow , pp. 341-352
    • Faraci, F.1
  • 40
    • 0025304361 scopus 로고
    • Time courses of behavioral and regional cerebral metabolic responses to different doses of meta-chlorophenylpiperazine in awake rats
    • Freo U., Soncrant T., Ricchieri G., Wozniak K., Larson D., Rapoport S. Time courses of behavioral and regional cerebral metabolic responses to different doses of meta-chlorophenylpiperazine in awake rats. Brain Res. 511:1990;209-216.
    • (1990) Brain Res. , vol.511 , pp. 209-216
    • Freo, U.1    Soncrant, T.2    Ricchieri, G.3    Wozniak, K.4    Larson, D.5    Rapoport, S.6
  • 42
    • 0028593855 scopus 로고
    • Prefrontal dysfunction in clinical depression
    • George M.S., Ketter T.A., Post R.M. Prefrontal dysfunction in clinical depression. Depression. 2:1994;59-72.
    • (1994) Depression , vol.2 , pp. 59-72
    • George, M.S.1    Ketter, T.A.2    Post, R.M.3
  • 43
    • 0031975288 scopus 로고    scopus 로고
    • Depression and the course of coronary artery disease
    • Glassman A.H., Shapiro P.A. Depression and the course of coronary artery disease. Am. J. Psychiatry. 155:1998;4-11.
    • (1998) Am. J. Psychiatry , vol.155 , pp. 4-11
    • Glassman, A.H.1    Shapiro, P.A.2
  • 46
    • 0038136036 scopus 로고    scopus 로고
    • Newer antidepressants
    • in: P. Goodnick (Ed.), American Psychiatric Press, Washington, DC
    • P. Goodnick, Newer antidepressants, in: P. Goodnick (Ed.), Predictors of Treatment Response in Mood Disorders, American Psychiatric Press, Washington, DC, 1996, pp. 57-94.
    • (1996) Predictors of Treatment Response in Mood Disorders , pp. 57-94
    • Goodnick, P.1
  • 47
    • 0028930655 scopus 로고
    • Neurochemistry and paroxetine response in major depression
    • Goodnick P., Henry J., Kumar A. Neurochemistry and paroxetine response in major depression. Biol. Psychiatry. 37:1995;417-419.
    • (1995) Biol. Psychiatry , vol.37 , pp. 417-419
    • Goodnick, P.1    Henry, J.2    Kumar, A.3
  • 50
    • 0022634095 scopus 로고
    • Local cerebral glucose utilisation following indoleamine- And piperazine-containing 5-hydroxytriptamine agonists
    • Grome J.J., Harper A.M. Local cerebral glucose utilisation following indoleamine- and piperazine-containing 5-hydroxytriptamine agonists. J. Neurochem. 46:1986;117-124.
    • (1986) J. Neurochem. , vol.46 , pp. 117-124
    • Grome, J.J.1    Harper, A.M.2
  • 55
    • 0027494593 scopus 로고
    • A double-blind trial of fluoxetine, 20 mg, and placebo in out-patients with DSM-III-R major depression and melancholia
    • Heiligenstein J.H., Tollefson G.D., Faries D.E. A double-blind trial of fluoxetine, 20 mg, and placebo in out-patients with DSM-III-R major depression and melancholia. Int. Clin. Psychopharmacol. 8:1993;247-251.
    • (1993) Int. Clin. Psychopharmacol. , vol.8 , pp. 247-251
    • Heiligenstein, J.H.1    Tollefson, G.D.2    Faries, D.E.3
  • 56
    • 0028832032 scopus 로고
    • Subcortical hyperintensities on magnetic resonance imaging: Clinical correlates and prognostic significance in patients with severe depression
    • Hickie I., Scott E., Mitchell P., Wilhelm K., Austin M.P., Bennett B. Subcortical hyperintensities on magnetic resonance imaging: clinical correlates and prognostic significance in patients with severe depression. Biol. Psychiatry. 37:1995;151-160.
    • (1995) Biol. Psychiatry , vol.37 , pp. 151-160
    • Hickie, I.1    Scott, E.2    Mitchell, P.3    Wilhelm, K.4    Austin, M.P.5    Bennett, B.6
  • 57
    • 0030983090 scopus 로고    scopus 로고
    • Effects of m-chlorophenylpiperazine on regional brain glucose utilization: A positron emission tomographic comparison of alcoholic and control subjects
    • Hommer D., Andreasen P., Rio D., Williams W., Ruttimann U., Momenan R., Zametkin A., Rawlings R., Linnoila M. Effects of m-chlorophenylpiperazine on regional brain glucose utilization: a positron emission tomographic comparison of alcoholic and control subjects. J. Neurosci. 17:1997;2796-2806.
    • (1997) J. Neurosci. , vol.17 , pp. 2796-2806
    • Hommer, D.1    Andreasen, P.2    Rio, D.3    Williams, W.4    Ruttimann, U.5    Momenan, R.6    Zametkin, A.7    Rawlings, R.8    Linnoila, M.9
  • 58
    • 0022621005 scopus 로고
    • Age differences in intercorrelations between regional cerebral metabolic rates for glucose
    • Horwitz B., Duara R., Rapoport S. Age differences in intercorrelations between regional cerebral metabolic rates for glucose. Ann. Neurol. 19:1986;60-67.
    • (1986) Ann. Neurol. , vol.19 , pp. 60-67
    • Horwitz, B.1    Duara, R.2    Rapoport, S.3
  • 59
    • 0028178378 scopus 로고
    • 1A receptors during ageing: Reversal by Ginkgo biloba extract (EGb 761)
    • 1A receptors during ageing: reversal by Ginkgo biloba extract (EGb 761). J. Pharm. Pharmacol. 46:1994;316-318.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 316-318
    • Huguet, F.1    Drieu, K.2    Piriou, A.3
  • 63
    • 0026515597 scopus 로고
    • Structure and function of the brain serotonin system
    • Jacobs B.L., Azmitia E.C. Structure and function of the brain serotonin system. Physiol. Rev. 72:1992;165-229.
    • (1992) Physiol. Rev. , vol.72 , pp. 165-229
    • Jacobs, B.L.1    Azmitia, E.C.2
  • 65
    • 0028285516 scopus 로고
    • Modulation of cortical neuronal activity by a serotonergic agent, a PET study in humans
    • Kapur S., Meyer J., Wilson A., Houle S., Brown G. Modulation of cortical neuronal activity by a serotonergic agent, a PET study in humans. Brain Res. 646:1994;292-294.
    • (1994) Brain Res. , vol.646 , pp. 292-294
    • Kapur, S.1    Meyer, J.2    Wilson, A.3    Houle, S.4    Brown, G.5
  • 66
    • 0030830518 scopus 로고    scopus 로고
    • In vivo imaging of neurotransmitter systems using radiolabeled receptor ligands
    • Kegeles L.S., Mann J.J. In vivo imaging of neurotransmitter systems using radiolabeled receptor ligands. Neuropsychopharmacology. 17:1997;293-307.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 293-307
    • Kegeles, L.S.1    Mann, J.J.2
  • 67
    • 0023889444 scopus 로고
    • Differential patterns of local cerebral glucose utilization in response to 5-hydroxytryptamine agonists
    • Kelly P.A., Davis C.J., Goodwin G.M. Differential patterns of local cerebral glucose utilization in response to 5-hydroxytryptamine agonists. Neuroscience. 25:1988;907-915.
    • (1988) Neuroscience , vol.25 , pp. 907-915
    • Kelly, P.A.1    Davis, C.J.2    Goodwin, G.M.3
  • 69
    • 0342297373 scopus 로고
    • Coupling of blood flow and metabolism in the brain
    • in: J.W. Phillis (Ed.), CRC Press, Boca Raton, FL
    • W. Kuchinsky, Coupling of blood flow and metabolism in the brain in: J.W. Phillis (Ed.), The Regulation of Cerebral Blood Flow, CRC Press, Boca Raton, FL, 1993, pp 269-280.
    • (1993) The Regulation of Cerebral Blood Flow , pp. 269-280
    • Kuchinsky, W.1
  • 71
    • 0027250868 scopus 로고
    • Regional cerebral glucose metabolism in late-life depression and Alzheimer disease: A preliminary positron emission tomography study
    • Kumar A., Newberg A., Alavi A., Berlin J., Smith R., Reivich M. Regional cerebral glucose metabolism in late-life depression and Alzheimer disease: a preliminary positron emission tomography study. Proc. Natl. Acad. Sci. 90:1993;7019-7023.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 7019-7023
    • Kumar, A.1    Newberg, A.2    Alavi, A.3    Berlin, J.4    Smith, R.5    Reivich, M.6
  • 72
    • 0029904877 scopus 로고    scopus 로고
    • Relapse prevention by means of paroxetine in ECT-treated patients with major depression, a comparison with imipramine and placebo in medium-term continuation therapy
    • Lauritzen L., Odgaard K., Clemmesen L., Lunde M., Ohrstrom J., Black C., Bech P. Relapse prevention by means of paroxetine in ECT-treated patients with major depression, a comparison with imipramine and placebo in medium-term continuation therapy. Acta Psychiatr. Scand. 94:1996;241-251.
    • (1996) Acta Psychiatr. Scand. , vol.94 , pp. 241-251
    • Lauritzen, L.1    Odgaard, K.2    Clemmesen, L.3    Lunde, M.4    Ohrstrom, J.5    Black, C.6    Bech, P.7
  • 73
    • 0024345644 scopus 로고
    • Evidence for a decline with age in behavioral responsivity to the serotonin agonist m-chlorophenylpiperazine, in healthy human subjects
    • Lawlor B., Sunderland T., Hill J., Mellow A., Molchan S., Mueller E., Jacobsen F., Murphy D. Evidence for a decline with age in behavioral responsivity to the serotonin agonist m-chlorophenylpiperazine, in healthy human subjects. Psychiatry Res. 29:1989;1-10.
    • (1989) Psychiatry Res. , vol.29 , pp. 1-10
    • Lawlor, B.1    Sunderland, T.2    Hill, J.3    Mellow, A.4    Molchan, S.5    Mueller, E.6    Jacobsen, F.7    Murphy, D.8
  • 75
    • 0029990720 scopus 로고    scopus 로고
    • Interrelationship of age, depression, and central serotonergic function: Evidence from fenfluramine challenge studies
    • Lerer B., Gillon D., Lichtenberg P., Gorfine M., Gelfin Y., Shapira A. Interrelationship of age, depression, and central serotonergic function: evidence from fenfluramine challenge studies. Int. Psychogeriatr. 8:1996;83-102.
    • (1996) Int. Psychogeriatr. , vol.8 , pp. 83-102
    • Lerer, B.1    Gillon, D.2    Lichtenberg, P.3    Gorfine, M.4    Gelfin, Y.5    Shapira, A.6
  • 77
    • 18244410775 scopus 로고    scopus 로고
    • Biological parameters in major depression: Effects of paroxetine, viloxazine, moclobemide, and electroconvulsive therapy, relation to early clinical outcome
    • Lestra C., d'Amato T., Ghaemmaghami C., Perret-Liaudet A., Broyer M., Renaud B., Dalery J., Chamba G. Biological parameters in major depression: effects of paroxetine, viloxazine, moclobemide, and electroconvulsive therapy, relation to early clinical outcome. Biol. Psychiatry. 44:1998;274-280.
    • (1998) Biol. Psychiatry , vol.44 , pp. 274-280
    • Lestra, C.1    D'Amato, T.2    Ghaemmaghami, C.3    Perret-Liaudet, A.4    Broyer, M.5    Renaud, B.6    Dalery, J.7    Chamba, G.8
  • 78
    • 0000587671 scopus 로고
    • The serotonin hypothesis of depression
    • in: F. Bloom, D. Kupfer (Eds.), Raven Press, New York
    • M. Maes, H. Meltzer, The serotonin hypothesis of depression, in: F. Bloom, D. Kupfer (Eds.), Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, 1995, pp. 933-944.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.2
  • 81
    • 2642619386 scopus 로고    scopus 로고
    • The neurobiology of suicide
    • Mann J.J. The neurobiology of suicide. Nat. Med. 4:1998;25-30.
    • (1998) Nat. Med. , vol.4 , pp. 25-30
    • Mann, J.J.1
  • 82
    • 0030048176 scopus 로고    scopus 로고
    • Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients
    • Mann J.J., Malone K.M., Diehl D.J., Perel J., Cooper T.B., Mintun M.A. Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients. Am. J. Psychiatry. 153:1996;174-182.
    • (1996) Am. J. Psychiatry , vol.153 , pp. 174-182
    • Mann, J.J.1    Malone, K.M.2    Diehl, D.J.3    Perel, J.4    Cooper, T.B.5    Mintun, M.A.6
  • 83
    • 0029928015 scopus 로고    scopus 로고
    • Positron emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers
    • Mann J.J., Malone K.M., Diehl D.J., Perel J., Nichols T.E., Mintun M.A. Positron emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers. J. Cereb. Blood Flow Metab. 16:1996;418-426.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 418-426
    • Mann, J.J.1    Malone, K.M.2    Diehl, D.J.3    Perel, J.4    Nichols, T.E.5    Mintun, M.A.6
  • 85
    • 0343521438 scopus 로고
    • Amine receptor binding and monoamine oxidase activity in postmortem human brain tissue: Effect of age, gender and postmortem delay
    • in: G.D. Burrows, T.R. Norman, L. Dennerstein (Eds.), John Libbey, London
    • J.J. Mann, C. Petito, M. Stanley, P.A. McBride, J. Chin, A. Philogene, Amine receptor binding and monoamine oxidase activity in postmortem human brain tissue: effect of age, gender and postmortem delay, in: G.D. Burrows, T.R. Norman, L. Dennerstein (Eds.), Clinical and Pharmacological Studies in Psychiatric Disorders, John Libbey, London, 1985, pp. 37-39.
    • (1985) Clinical and Pharmacological Studies in Psychiatric Disorders , pp. 37-39
    • Mann, J.J.1    Petito, C.2    Stanley, M.3    McBride, P.A.4    Chin, J.5    Philogene, A.6
  • 88
    • 0021228324 scopus 로고
    • Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age
    • Marcusson J.O., Morgan D.G., Winblad B., Finch C.E. Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age. Brain Res. 311:1984;51-56.
    • (1984) Brain Res. , vol.311 , pp. 51-56
    • Marcusson, J.O.1    Morgan, D.G.2    Winblad, B.3    Finch, C.E.4
  • 89
    • 0021744675 scopus 로고
    • Effects of age on human brain serotonin (S-1) binding sites
    • Marcusson J.O., Oreland L., Winblad B. Effects of age on human brain serotonin (S-1) binding sites. J. Neurochem. 43:1984;1699-1705.
    • (1984) J. Neurochem. , vol.43 , pp. 1699-1705
    • Marcusson, J.O.1    Oreland, L.2    Winblad, B.3
  • 94
    • 0025321507 scopus 로고
    • Effects of age and gender on CNS serotonergic responsivity in normal adults
    • McBride P.A., Tierney H., DeMeo M., Chen J.S., Mann J.J. Effects of age and gender on CNS serotonergic responsivity in normal adults. Biol. Psychiatry. 27:1990;1143-1155.
    • (1990) Biol. Psychiatry , vol.27 , pp. 1143-1155
    • McBride, P.A.1    Tierney, H.2    Demeo, M.3    Chen, J.S.4    Mann, J.J.5
  • 95
    • 0011957096 scopus 로고
    • The physiology and regulation of cerebral blood flow
    • in: S. Knezevic, V.A. Maximilian, Z. Mubrin, I. Prohovnik, J. Wade (Eds.), Erlbaum, Hillsdale, NJ
    • J. McCulloch, The physiology and regulation of cerebral blood flow, in: S. Knezevic, V.A. Maximilian, Z. Mubrin, I. Prohovnik, J. Wade (Eds.), Handbook of Regional Cerebral Blood Flow, Erlbaum, Hillsdale, NJ, 1988, pp. 1-24.
    • (1988) Handbook of Regional Cerebral Blood Flow , pp. 1-24
    • McCulloch, J.1
  • 96
    • 0026058441 scopus 로고
    • Serotonin, memory, and the aging brain
    • McEntee W.J., Crook T.H. Serotonin, memory, and the aging brain. Psychopharmacology. 103:1991;143-149.
    • (1991) Psychopharmacology , vol.103 , pp. 143-149
    • McEntee, W.J.1    Crook, T.H.2
  • 97
    • 0017336665 scopus 로고
    • Aging-induced changes in acetylcholine and serotonin content of discrete brain nuclei
    • Meek J.L., Bertilsson L., Cheney D.L., Zsilla G., Costa E. Aging-induced changes in acetylcholine and serotonin content of discrete brain nuclei. J. Gerontol. 32:1977;129-131.
    • (1977) J. Gerontol. , vol.32 , pp. 129-131
    • Meek, J.L.1    Bertilsson, L.2    Cheney, D.L.3    Zsilla, G.4    Costa, E.5
  • 103
    • 0029788383 scopus 로고    scopus 로고
    • Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging
    • Meltzer C.C., Zubieta J.K., Brandt J., Tune L.E., Mayberg H.S., Frost J.J. Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology. 47:1996;454-461.
    • (1996) Neurology , vol.47 , pp. 454-461
    • Meltzer, C.C.1    Zubieta, J.K.2    Brandt, J.3    Tune, L.E.4    Mayberg, H.S.5    Frost, J.J.6
  • 107
    • 0025968862 scopus 로고
    • 3 antagonist ondansetron: A 2-deoxyglucose autoradiographic study in the rat
    • 3 antagonist ondansetron: a 2-deoxyglucose autoradiographic study in the rat. Brain Res. 538:1991;289-294.
    • (1991) Brain Res. , vol.538 , pp. 289-294
    • Mitchell, E.A.1    Pratt, J.A.2
  • 108
    • 0026322181 scopus 로고
    • Endocrine and amine responses to D,L-fenfluramine in normal subjects
    • Mitchell P.B., Smyth G. Endocrine and amine responses to D,L-fenfluramine in normal subjects. Psychiatry Res. 39:1991;141-153.
    • (1991) Psychiatry Res. , vol.39 , pp. 141-153
    • Mitchell, P.B.1    Smyth, G.2
  • 109
    • 0031469040 scopus 로고    scopus 로고
    • Divergent expression of regional metabolic topographies in Parkinson's disease and normal aging
    • Moeller J.R., Eidelberg D. Divergent expression of regional metabolic topographies in Parkinson's disease and normal aging. Brain. 120:1997;197-206.
    • (1997) Brain , vol.120 , pp. 197-206
    • Moeller, J.R.1    Eidelberg, D.2
  • 111
    • 0023424904 scopus 로고
    • Scaled subprofile model: A statistical approach to the analysis of functional patterns in positron emission tomographic data
    • Moeller J.R., Strother S.C., Sidtis J.J., Rottenberg D.A. Scaled subprofile model: a statistical approach to the analysis of functional patterns in positron emission tomographic data. J. Cereb. Blood Flow Metab. 7:1987;649-658.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 649-658
    • Moeller, J.R.1    Strother, S.C.2    Sidtis, J.J.3    Rottenberg, D.A.4
  • 112
    • 0023180069 scopus 로고
    • The dopamine and serotonin systems during aging in human and rodent brain. A brief review
    • Morgan D.G. The dopamine and serotonin systems during aging in human and rodent brain. A brief review. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 11:1987;153-157.
    • (1987) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.11 , pp. 153-157
    • Morgan, D.G.1
  • 114
    • 0031822289 scopus 로고    scopus 로고
    • The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
    • Musselman D.L., Evans D.L., Nemeroff C.B. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch. Gen. Psychiatry. 55:1998;580-592.
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 580-592
    • Musselman, D.L.1    Evans, D.L.2    Nemeroff, C.B.3
  • 117
    • 0032375183 scopus 로고    scopus 로고
    • Differential response to antidepressants in melancholic and severe depression
    • Nobler M.S., Roose S.P. Differential response to antidepressants in melancholic and severe depression. Psychiatric Ann. 28:1998;84-88.
    • (1998) Psychiatric Ann. , vol.28 , pp. 84-88
    • Nobler, M.S.1    Roose, S.P.2
  • 122
    • 0028886567 scopus 로고
    • Do the endocrine and subjective effects of D-fenfluramine predict response to selective serotonin reuptake inhibitors?
    • Park S.B., Williamson D.J., Cowen P.J. Do the endocrine and subjective effects of D-fenfluramine predict response to selective serotonin reuptake inhibitors? Int. Clin. Psychopharmacol. 10:1995;215-220.
    • (1995) Int. Clin. Psychopharmacol. , vol.10 , pp. 215-220
    • Park, S.B.1    Williamson, D.J.2    Cowen, P.J.3
  • 123
    • 0345215154 scopus 로고    scopus 로고
    • Relationship between blood serotonergic variables, melancholic traits, and response to antidepressant treatments
    • Perez V., Bel N., Celada P., Ortiz J., Alvarez E., Artigas F. Relationship between blood serotonergic variables, melancholic traits, and response to antidepressant treatments. J. Clin. Psychopharmacol. 18:1998;222-230.
    • (1998) J. Clin. Psychopharmacol. , vol.18 , pp. 222-230
    • Perez, V.1    Bel, N.2    Celada, P.3    Ortiz, J.4    Alvarez, E.5    Artigas, F.6
  • 124
    • 0030594646 scopus 로고    scopus 로고
    • Pharmacotherapy for major depression with melancholic features: Relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants
    • Perry P.J. Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. J. Affective Disord. 39:1996;1-6.
    • (1996) J. Affective Disord. , vol.39 , pp. 1-6
    • Perry, P.J.1
  • 125
    • 0031824258 scopus 로고    scopus 로고
    • Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping
    • Petit-Taboue M.C., Landeau B., Desson J.F., Desgranges B., Baron J.C. Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping. Neuroimage. 7:1998;176-184.
    • (1998) Neuroimage , vol.7 , pp. 176-184
    • Petit-Taboue, M.C.1    Landeau, B.2    Desson, J.F.3    Desgranges, B.4    Baron, J.C.5
  • 126
    • 0001860679 scopus 로고
    • Neurobiology of aging
    • in: C.E. Coffey, J.L. Cummings (Eds.), American Psychiatric Press, Washington, DC
    • R.E. Powers, Neurobiology of aging, in: C.E. Coffey, J.L. Cummings (Eds.), Textbook of Geriatric Neuropsychiatry, American Psychiatric Press, Washington, DC, 1994, pp. 36-69.
    • (1994) Textbook of Geriatric Neuropsychiatry , pp. 36-69
    • Powers, R.E.1
  • 127
    • 0031862870 scopus 로고    scopus 로고
    • Diminished serotonin-mediated prolactin responses in nondepressed stroke patients compared with healthy normal subjects
    • Ramasubbu R., Flint A., Brown G., Awad G., Kennedy S. Diminished serotonin-mediated prolactin responses in nondepressed stroke patients compared with healthy normal subjects. Stroke. 29:1998;1293-1298.
    • (1998) Stroke , vol.29 , pp. 1293-1298
    • Ramasubbu, R.1    Flint, A.2    Brown, G.3    Awad, G.4    Kennedy, S.5
  • 129
    • 0016431015 scopus 로고
    • Changes in monoamine oxidase and monoamines with human development and aging
    • Robinson D.S. Changes in monoamine oxidase and monoamines with human development and aging. Fed. Proc. 34:1975;103-107.
    • (1975) Fed. Proc. , vol.34 , pp. 103-107
    • Robinson, D.S.1
  • 130
    • 0027140313 scopus 로고
    • Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats
    • Robson L., Gower A.J., Kendall D.A., Marsden C.A. Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats. Psychopharmacology. 113:1993;274-281.
    • (1993) Psychopharmacology , vol.113 , pp. 274-281
    • Robson, L.1    Gower, A.J.2    Kendall, D.A.3    Marsden, C.A.4
  • 131
    • 0028117844 scopus 로고
    • Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia
    • Roose S.P., Glassman A.H., Attia E., Woodring S. Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia. Am. J. Psychiatry. 151:1994;1735-1739.
    • (1994) Am. J. Psychiatry , vol.151 , pp. 1735-1739
    • Roose, S.P.1    Glassman, A.H.2    Attia, E.3    Woodring, S.4
  • 132
    • 0031841941 scopus 로고    scopus 로고
    • Antidepressant response in late-life depression
    • Roose S.P., Suthers K.M. Antidepressant response in late-life depression. J. Clin. Psychiatry. 59:1998;4-8.
    • (1998) J. Clin. Psychiatry , vol.59 , pp. 4-8
    • Roose, S.P.1    Suthers, K.M.2
  • 135
    • 0031718567 scopus 로고    scopus 로고
    • Child and adolescent mood disorders - Experience with serotonin-based therapies
    • Ryan N.D., Varma D. Child and adolescent mood disorders - experience with serotonin-based therapies. Biol. Psychiatry. 44:1998;336-340.
    • (1998) Biol. Psychiatry , vol.44 , pp. 336-340
    • Ryan, N.D.1    Varma, D.2
  • 137
  • 140
    • 0027319386 scopus 로고
    • Regional cerebral blood flow in mood disorders: II. Comparison of major depression and Alzheimer's disease
    • Sackeim H.A., Prohovnik I., Moeller J.R., Mayeux R., Stern Y., Devanand D. Regional cerebral blood flow in mood disorders: II. Comparison of major depression and Alzheimer's disease. J. Nucl. Med. 34:1993;1090-1101.
    • (1993) J. Nucl. Med. , vol.34 , pp. 1090-1101
    • Sackeim, H.A.1    Prohovnik, I.2    Moeller, J.R.3    Mayeux, R.4    Stern, Y.5    Devanand, D.6
  • 141
    • 0032146741 scopus 로고    scopus 로고
    • Intravenous clomipramine challenge in obsessive-compulsive disorder: Predicting response to oral therapy at eight weeks
    • Sallee F.R., Koran L.M., Pallanti S., Carson S.W., Sethuraman G. Intravenous clomipramine challenge in obsessive-compulsive disorder: predicting response to oral therapy at eight weeks. Biol. Psychiatry. 44:1998;220-227.
    • (1998) Biol. Psychiatry , vol.44 , pp. 220-227
    • Sallee, F.R.1    Koran, L.M.2    Pallanti, S.3    Carson, S.W.4    Sethuraman, G.5
  • 145
    • 0018222978 scopus 로고
    • The alteration of serotonin binding sites in aged human brain
    • Shih J.C., Young H. The alteration of serotonin binding sites in aged human brain. Life Sci. 23:1978;1441-1448.
    • (1978) Life Sci. , vol.23 , pp. 1441-1448
    • Shih, J.C.1    Young, H.2
  • 146
    • 0032585590 scopus 로고    scopus 로고
    • Quantitative PET analysis of regional cerebral blood flow and glucose and oxygen metabolism in response to fenfluramine in living porcine brain
    • Smith D.F., Poulsen P.H., Ishizu K., Sakoh M., Hansen S.B., Gee A.D., Bender D., Gjedde A. Quantitative PET analysis of regional cerebral blood flow and glucose and oxygen metabolism in response to fenfluramine in living porcine brain. J. Neurosci. Methods. 86:1998;17-23.
    • (1998) J. Neurosci. Methods , vol.86 , pp. 17-23
    • Smith, D.F.1    Poulsen, P.H.2    Ishizu, K.3    Sakoh, M.4    Hansen, S.B.5    Gee, A.D.6    Bender, D.7    Gjedde, A.8
  • 147
    • 0030862061 scopus 로고    scopus 로고
    • The functional neuroanatomy of mood disorders
    • Soares J.C., Mann J.J. The functional neuroanatomy of mood disorders. J. Psychiatr. Res. 31:1997;393-432.
    • (1997) J. Psychiatr. Res. , vol.31 , pp. 393-432
    • Soares, J.C.1    Mann, J.J.2
  • 149
    • 0032191771 scopus 로고    scopus 로고
    • Imaging of the serotonergic system: Interactions of neuroanatomical and functional abnormalities of depression
    • Staley J.K., Malison R.T., Innis R.B. Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression. Biol. Psychiatry. 44:1998;534-549.
    • (1998) Biol. Psychiatry , vol.44 , pp. 534-549
    • Staley, J.K.1    Malison, R.T.2    Innis, R.B.3
  • 150
    • 0027080402 scopus 로고
    • Paroxetine in the treatment of melancholia and severe depression
    • Tignol J., Stoker M.J., Dunbar G.C. Paroxetine in the treatment of melancholia and severe depression. Int. Clin. Psychopharmacol. 7:1992;91-94.
    • (1992) Int. Clin. Psychopharmacol. , vol.7 , pp. 91-94
    • Tignol, J.1    Stoker, M.J.2    Dunbar, G.C.3
  • 151
    • 0027427748 scopus 로고
    • Analysis of the Hamilton depression rating scale factors from a double-blind, placebo-controlled trial of fluoxetine in geriatric major depression
    • Tollefson G.D., Holman S.L. Analysis of the Hamilton depression rating scale factors from a double-blind, placebo-controlled trial of fluoxetine in geriatric major depression. Int. Clin. Psychopharmacol. 8:1993;253-259.
    • (1993) Int. Clin. Psychopharmacol. , vol.8 , pp. 253-259
    • Tollefson, G.D.1    Holman, S.L.2
  • 152
    • 0026700930 scopus 로고
    • Regulation of cortical blood flow by the dorsal raphe nucleus: Topographic organization of cerebrovascular regulatory regions
    • Underwood M.D., Bakalian M.J., Arango V., Smith R.W., Mann J.J. Regulation of cortical blood flow by the dorsal raphe nucleus: topographic organization of cerebrovascular regulatory regions. J. Cereb. Blood Flow Metab. 12:1992;664-673.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 664-673
    • Underwood, M.D.1    Bakalian, M.J.2    Arango, V.3    Smith, R.W.4    Mann, J.J.5
  • 154
    • 0027317069 scopus 로고
    • Ultrastructure of serotonin-immunoreactive terminals in the core and shell of the rat nucleus accumbens: Cellular substrates for interactions with catecholamine afferents
    • Van Bockstaele E.J., Pickel P.M. Ultrastructure of serotonin-immunoreactive terminals in the core and shell of the rat nucleus accumbens: cellular substrates for interactions with catecholamine afferents. J. Comp. Neurol. 334:1993;603-617.
    • (1993) J. Comp. Neurol. , vol.334 , pp. 603-617
    • Van Bockstaele, E.J.1    Pickel, P.M.2
  • 158
    • 0023522075 scopus 로고
    • 1A receptor agonist ipsapirone on the local cerebral glucose utilization of the rat hippocampus
    • 1A receptor agonist ipsapirone on the local cerebral glucose utilization of the rat hippocampus. Brain Res. 436:1987;283-290.
    • (1987) Brain Res. , vol.436 , pp. 283-290
    • Wree, A.1    Zilles, K.2    Schleicher, A.3    Horvath, E.4    Traber, J.5
  • 159
    • 0025767055 scopus 로고
    • Serotonergic ligand binding in aging brain of experimental animals
    • Yamaguchi T., Yamagata A. Serotonergic ligand binding in aging brain of experimental animals. Neurochem. Res. 16:1991;469-473.
    • (1991) Neurochem. Res. , vol.16 , pp. 469-473
    • Yamaguchi, T.1    Yamagata, A.2
  • 160
    • 0023712050 scopus 로고
    • Sensitivity of cerebral glucose metabolism to age, gender, brain volume, brain atrophy, and cerebrovascular risk factors
    • Yoshii F., Barker W.W., Chang J.Y., Loewenstein D., Apicella A., Smith D., Boothe T., Ginsberg M.D., Pascal S., Duara R. Sensitivity of cerebral glucose metabolism to age, gender, brain volume, brain atrophy, and cerebrovascular risk factors. J. Cereb. Blood Flow Metab. 8:1988;654-661.
    • (1988) J. Cereb. Blood Flow Metab. , vol.8 , pp. 654-661
    • Yoshii, F.1    Barker, W.W.2    Chang, J.Y.3    Loewenstein, D.4    Apicella, A.5    Smith6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.