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Volumn 193, Issue , 2003, Pages 58-69

The role of CD95 in the regulation of peripheral T-cell apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 3; CASPASE 8; CASPASE 9; CD28 ANTIGEN; ENZYME PRECURSOR; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; RAF PROTEIN; STAT PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 0037833695     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2003.00047.x     Document Type: Review
Times cited : (173)

References (145)
  • 1
    • 0037018098 scopus 로고    scopus 로고
    • Estimating the precursor frequency of naïve antigen-specifc CD8 T cells
    • Blattman JN, et al. Estimating the precursor frequency of naïve antigen-specifc CD8 T cells. J Exp Med 2002;195:657-664.
    • (2002) J Exp Med , vol.195 , pp. 657-664
    • Blattman, J.N.1
  • 2
    • 0035854526 scopus 로고    scopus 로고
    • T cell death and memory
    • Sprent J, Tough DF. T cell death and memory. Science 2001;293:245-248.
    • (2001) Science , vol.293 , pp. 245-248
    • Sprent, J.1    Tough, D.F.2
  • 4
    • 0033491193 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas)-mediated apoptosis: Live and let die
    • Krammer PH. CD95 (APO-1/Fas)-mediated apoptosis: live and let die. Adv Immunol 1999;71:163-210.
    • (1999) Adv Immunol , vol.71 , pp. 163-210
    • Krammer, P.H.1
  • 5
    • 0031452949 scopus 로고    scopus 로고
    • Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing
    • Suda T, Hashimoto H, Tanaka M, Ocki T, Nagata S. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 1997;186:2045-2050.
    • (1997) J Exp Med , vol.186 , pp. 2045-2050
    • Suda, T.1    Hashimoto, H.2    Tanaka, M.3    Ocki, T.4    Nagata, S.5
  • 6
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • Schneider P, Holler N, Bodmer JL, et al. Conversion of membrane-bound Fas (CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 1998;187:1205-1213.
    • (1998) J Exp Med , vol.187 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.L.3
  • 7
    • 0035318305 scopus 로고    scopus 로고
    • Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity
    • Aoki K, Kurooka M, Chen JJ, Petryniak J, Nabel EG, Nabel GJ. Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity. Nat Immunol 2001;2:333-337.
    • (2001) Nat Immunol , vol.2 , pp. 333-337
    • Aoki, K.1    Kurooka, M.2    Chen, J.J.3    Petryniak, J.4    Nabel, E.G.5    Nabel, G.J.6
  • 8
    • 0024347970 scopus 로고
    • Monoclonal antibody-mediated tumor regression by induction of apoptosis
    • Trauth BC, et al. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989;245:301-305.
    • (1989) Science , vol.245 , pp. 301-305
    • Trauth, B.C.1
  • 9
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-reducing signahng complex (DISC) with the receptor
    • Kischkel FC, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-reducing signahng complex (DISC) with the receptor. EMBO J 1995;14:5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1
  • 10
    • 0033662433 scopus 로고    scopus 로고
    • Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
    • Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000;12:611-620.
    • (2000) Immunity , vol.12 , pp. 611-620
    • Kischkel, F.C.1    Lawrence, D.A.2    Chuntharapai, A.3    Schow, P.4    Kim, K.J.5    Ashkenazi, A.6
  • 11
    • 0033667778 scopus 로고    scopus 로고
    • FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
    • Sprick MR, et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 2000;12:599-609.
    • (2000) Immunity , vol.12 , pp. 599-609
    • Sprick, M.R.1
  • 12
    • 0035399893 scopus 로고    scopus 로고
    • Biochemistry and function of the DISC
    • Walczak H, Sprick MR. Biochemistry and function of the DISC. Trends Biochem Sci 2001;26:452-453.
    • (2001) Trends Biochem Sci , vol.26 , pp. 452-453
    • Walczak, H.1    Sprick, M.R.2
  • 13
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996;85:817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1
  • 14
    • 0036022407 scopus 로고    scopus 로고
    • Initiator caspases in apoptosis signaling pathways
    • Chen M, Wang J. Initiator caspases in apoptosis signaling pathways. Apoptosis 2002;7:313-319.
    • (2002) Apoptosis , vol.7 , pp. 313-319
    • Chen, M.1    Wang, J.2
  • 15
    • 0035824635 scopus 로고    scopus 로고
    • Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
    • Kischkel FC, et al. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 2001;276:46639-46646.
    • (2001) J Biol Chem , vol.276 , pp. 46639-46646
    • Kischkel, F.C.1
  • 16
    • 0037009370 scopus 로고    scopus 로고
    • Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but cannot functionally substitute caspase-8
    • Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but cannot functionally substitute caspase-8. EMBO J 2002;21:4520-4530.
    • (2002) EMBO J , vol.21 , pp. 4520-4530
    • Sprick, M.R.1    Rieser, E.2    Stahl, H.3    Grosse-Wilde, A.4    Weigand, M.A.5    Walczak, H.6
  • 18
    • 0033790715 scopus 로고    scopus 로고
    • TRAIL receptor-2 signals apoptosis through FADD and caspase-8
    • Bodmer JL, et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat Cell Biol 2000;2:241-243.
    • (2000) Nat Cell Biol , vol.2 , pp. 241-243
    • Bodmer, J.L.1
  • 19
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 1999;68:383-424.
    • (1999) Annu Rev Biochem , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 20
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema JP, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997;16:2794-2804.
    • (1997) EMBO J , vol.16 , pp. 2794-2804
    • Medema, J.P.1
  • 21
    • 0034733584 scopus 로고    scopus 로고
    • Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
    • Siegel RM, et al. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science 2000;288:2354-2357.
    • (2000) Science , vol.288 , pp. 2354-2357
    • Siegel, R.M.1
  • 22
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan FK, Chun HJ, Zheng L, Siegel RM, Bui KL, Lenardo MJ. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 2000;288:2351-2354.
    • (2000) Science , vol.288 , pp. 2351-2354
    • Chan, F.K.1    Chun, H.J.2    Zheng, L.3    Siegel, R.M.4    Bui, K.L.5    Lenardo, M.J.6
  • 24
    • 0032536771 scopus 로고    scopus 로고
    • Two CD95 (APO-1/Fas) signaling pathways
    • Scaffidi C, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17:1675-1687.
    • (1998) EMBO J , vol.17 , pp. 1675-1687
    • Scaffidi, C.1
  • 25
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 26
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mechates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mechates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 27
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
    • Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000;7:1166-1173.
    • (2000) Cell Death Differ , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3    Weiler, S.4    Oh, K.J.5    Schlesinger, P.H.6
  • 28
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 29
    • 0033607006 scopus 로고    scopus 로고
    • Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
    • Yin XM, et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999;400:886-891.
    • (1999) Nature , vol.400 , pp. 886-891
    • Yin, X.M.1
  • 30
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001;292:727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1
  • 31
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
    • Lindsten T, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell 2000;6:1389-1399.
    • (2000) Mol Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1
  • 32
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A, Harris AW, Huang DC, Krammer PH, Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J 1995;14:6136-6147.
    • (1995) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 33
    • 13344279418 scopus 로고    scopus 로고
    • Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice
    • Lacronique V, et al. Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice. Nat Med 1996;2:80-86.
    • (1996) Nat Med , vol.2 , pp. 80-86
    • Lacronique, V.1
  • 34
    • 0029976410 scopus 로고    scopus 로고
    • A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection
    • Rodriguez I, Matsuura K, Khatib K, Reed JC, Nagata S, Vassalli P. A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. J Exp Med 1996;183:1031-1036.
    • (1996) J Exp Med , vol.183 , pp. 1031-1036
    • Rodriguez, I.1    Matsuura, K.2    Khatib, K.3    Reed, J.C.4    Nagata, S.5    Vassalli, P.6
  • 35
    • 0035192884 scopus 로고    scopus 로고
    • FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
    • Krueger A, Baumann S, Krammer PH, Kirchhoff S. FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol 2001;21:8247-8254.
    • (2001) Mol Cell Biol , vol.21 , pp. 8247-8254
    • Krueger, A.1    Baumann, S.2    Krammer, P.H.3    Kirchhoff, S.4
  • 36
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • Irmler M, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1
  • 37
    • 0030810981 scopus 로고    scopus 로고
    • FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
    • Srinivasula SM, et al. FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J Biol Chem 1997;272:18542-18545.
    • (1997) J Biol Chem , vol.272 , pp. 18542-18545
    • Srinivasula, S.M.1
  • 39
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- and caspase-related inducer of apoptosis
    • Shu HB, Halpin DR, Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997;6:751-763.
    • (1997) Immunity , vol.6 , pp. 751-763
    • Shu, H.B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 40
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE, a novel inhibitor of rumor necrosis factor receptor-1- and CD-95-induced apoptosis
    • Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of rumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 1997;272: 17255-17257.
    • (1997) J Biol Chem , vol.272 , pp. 17255-17257
    • Hu, S.1    Vincenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 41
    • 0030758315 scopus 로고    scopus 로고
    • MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
    • Han DK, et al. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci USA 1997;94:11333-11338.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11333-11338
    • Han, D.K.1
  • 42
    • 0030961084 scopus 로고    scopus 로고
    • CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
    • Inohara N, Koseki T, Hu Y, Chen S, Nunez G. CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc Natl Acad Sci USA 1997;94:10717-10722.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10717-10722
    • Inohara, N.1    Koseki, T.2    Hu, Y.3    Chen, S.4    Nunez, G.5
  • 43
    • 7344220967 scopus 로고    scopus 로고
    • Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
    • Rasper DM, et al. Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ 1998;5:271-288.
    • (1998) Cell Death Differ , vol.5 , pp. 271-288
    • Rasper, D.M.1
  • 44
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C, Schmitz I, Krammer PH, Peter ME. The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 1999;274:1541-1548.
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 45
    • 0035827569 scopus 로고    scopus 로고
    • Cellular flice-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the cd95 death-inducing signaling complex
    • Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. Cellular flice-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the cd95 death-inducing signaling complex. J Biol Chem 2001;276:20633-20640.
    • (2001) J Biol Chem , vol.276 , pp. 20633-20640
    • Krueger, A.1    Schmitz, I.2    Baumann, S.3    Krammer, P.H.4    Kirchhoff, S.5
  • 46
    • 0037099678 scopus 로고    scopus 로고
    • c-FLIP (L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
    • Chang DW, et al. c-FLIP (L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J 2002;21:3704-3714.
    • (2002) EMBO J , vol.21 , pp. 3704-3714
    • Chang, D.W.1
  • 47
    • 0032539007 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by reduced FLICE-inhibitory protein expression
    • Yeh JH, Hsu SC, Han SH, Lai MZ. Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by reduced FLICE-inhibitory protein expression. J Exp Med 1998;188:1795-1802.
    • (1998) J Exp Med , vol.188 , pp. 1795-1802
    • Yeh, J.H.1    Hsu, S.C.2    Han, S.H.3    Lai, M.Z.4
  • 48
    • 0035831556 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
    • Panka DJ, Mano T, Suhara T, Walsh K, Mier JW. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. J Biol Chem 2001;276:6893-6896.
    • (2001) J Biol Chem , vol.276 , pp. 6893-6896
    • Panka, D.J.1    Mano, T.2    Suhara, T.3    Walsh, K.4    Mier, J.W.5
  • 49
    • 0034744033 scopus 로고    scopus 로고
    • NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
    • Kreuz S, Siegmund D, Scheurich P, Wajant H. NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Mol Cell Biol 2001;21:3964-3973.
    • (2001) Mol Cell Biol , vol.21 , pp. 3964-3973
    • Kreuz, S.1    Siegmund, D.2    Scheurich, P.3    Wajant, H.4
  • 51
    • 0034648529 scopus 로고    scopus 로고
    • Activation of the NF-kappaB pathway by caspase 8 and its homologs
    • Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L. Activation of the NF-kappaB pathway by caspase 8 and its homologs. Oncogene 2000;19:4451-4460.
    • (2000) Oncogene , vol.19 , pp. 4451-4460
    • Chaudhary, P.M.1    Eby, M.T.2    Jasmin, A.3    Kumar, A.4    Liu, L.5    Hood, L.6
  • 52
    • 0034646478 scopus 로고    scopus 로고
    • Activation of NF-kappaB by FADD, Casper, and caspase-8
    • Hu WH, Johnson H, Shu HB. Activation of NF-kappaB by FADD, Casper, and caspase-8. J Biol Chem 2000;275:10838-10844.
    • (2000) J Biol Chem , vol.275 , pp. 10838-10844
    • Hu, W.H.1    Johnson, H.2    Shu, H.B.3
  • 53
    • 18744425429 scopus 로고    scopus 로고
    • The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
    • Kataoka T, et al. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr Biol 2000;10:640-648.
    • (2000) Curr Biol , vol.10 , pp. 640-648
    • Kataoka, T.1
  • 54
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen PL, Eisenberg RA. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1991;9:243-269.
    • (1991) Annu Rev Immunol , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 55
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992;356:314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 56
    • 0027477302 scopus 로고
    • Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice
    • Adachi M, Watanabe-Fukunaga R, Nagata S. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci USA 1993;90:1756-1760.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1756-1760
    • Adachi, M.1    Watanabe-Fukunaga, R.2    Nagata, S.3
  • 57
    • 0027220216 scopus 로고
    • The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn
    • Chu JL, Drappa J, Parnassa A, Elkon KB. The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn. J Exp Med 1993;178:723-730.
    • (1993) J Exp Med , vol.178 , pp. 723-730
    • Chu, J.L.1    Drappa, J.2    Parnassa, A.3    Elkon, K.B.4
  • 58
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi T, Tanaka M, Brannan CI, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994;76:969-976.
    • (1994) Cell , vol.76 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3
  • 59
    • 0028429962 scopus 로고
    • The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster
    • Lynch DH, et al. The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1994;1:131-136.
    • (1994) Immunity , vol.1 , pp. 131-136
    • Lynch, D.H.1
  • 60
    • 0024368696 scopus 로고
    • Cyclosporin A inhibits activation-reduced cell death in T-cell hybridomas and thymocytes
    • Shi YF, Sahai BM, Green DR. Cyclosporin A inhibits activation-reduced cell death in T-cell hybridomas and thymocytes. Nature 1989;339:625-626.
    • (1989) Nature , vol.339 , pp. 625-626
    • Shi, Y.F.1    Sahai, B.M.2    Green, D.R.3
  • 61
    • 0036165409 scopus 로고    scopus 로고
    • The death of a T-cell: Expression of the CD95 ligand
    • Li-Weber M, Krammer PH. The death of a T-cell: expression of the CD95 ligand. Cell Death Differ 2002;9:101-103.
    • (2002) Cell Death Differ , vol.9 , pp. 101-103
    • Li-Weber, M.1    Krammer, P.H.2
  • 63
    • 0028893078 scopus 로고
    • Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju ST, et al. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995;373:444-448.
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.T.1
  • 64
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner T, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995;373:441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1
  • 65
    • 0028909197 scopus 로고
    • Fas ligand mediates activation-induced cell death in human T lymphocytes
    • Alderson MR, et al. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 1995;181:71-77.
    • (1995) J Exp Med , vol.181 , pp. 71-77
    • Alderson, M.R.1
  • 66
    • 0027183703 scopus 로고
    • Activation interferes with the APO-1 pathway in mature human T cells
    • Klas C, Debatin KM, Jonker RR, Krammer PH. Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 1993;5:625-630.
    • (1993) Int Immunol , vol.5 , pp. 625-630
    • Klas, C.1    Debatin, K.M.2    Jonker, R.R.3    Krammer, P.H.4
  • 67
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
    • Refaeli Y, Van Parijs L, London CA, Tschopp J, Abbas AK. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998;8:615-623.
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    Van Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 68
    • 0033136321 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis
    • Algeciras-Schimnich A, Griffith TS, Lynch DH, Paya CV. Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis. J Immunol 1999;162:5205-5211.
    • (1999) J Immunol , vol.162 , pp. 5205-5211
    • Algeciras-Schimnich, A.1    Griffith, T.S.2    Lynch, D.H.3    Paya, C.V.4
  • 69
    • 0030949563 scopus 로고    scopus 로고
    • Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex
    • Peter ME, Kischkel FC, Scheuerpflug CG, Medema JP, Debatin KM, Krammer PH. Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex. Eur J Immunol 1997;27:1207-1212.
    • (1997) Eur J Immunol , vol.27 , pp. 1207-1212
    • Peter, M.E.1    Kischkel, F.C.2    Scheuerpflug, C.G.3    Medema, J.P.4    Debatin, K.M.5    Krammer, P.H.6
  • 70
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
    • Lenardo MJ. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature 1991;353:858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 71
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-261.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horak, I.6
  • 72
    • 0029028363 scopus 로고
    • Deregulated T cell activation and autoimmumty in mice lacking interleukin-2 receptor beta
    • Suzuki H, et al. Deregulated T cell activation and autoimmumty in mice lacking interleukin-2 receptor beta. Science 1995;268:1472-1476.
    • (1995) Science , vol.268 , pp. 1472-1476
    • Suzuki, H.1
  • 73
    • 0028784289 scopus 로고
    • Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995;3:521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 74
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor
    • Van Parijs L, Biuckians A, Ibragimov A, Alt FW, Willerford DM, Abbas AK. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. J Immunol 1997;158:3738-3745.
    • (1997) J Immunol , vol.158 , pp. 3738-3745
    • Van Parijs, L.1    Biuckians, A.2    Ibragimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 75
    • 0029118133 scopus 로고
    • Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice
    • Kneitz B, Herrmann T, Yonehara S, Schimpl A. Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice. Eur J Immunol 1995;25:2572-2577.
    • (1995) Eur J Immunol , vol.25 , pp. 2572-2577
    • Kneitz, B.1    Herrmann, T.2    Yonehara, S.3    Schimpl, A.4
  • 76
    • 0029046208 scopus 로고
    • Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission
    • Fujii H, et al. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission. Proc Natl Acad Sci USA 1995;92:5482-5486.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5482-5486
    • Fujii, H.1
  • 77
    • 0027993022 scopus 로고
    • Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
    • Miyazaki T, et al. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science 1994;266:1045-1047.
    • (1994) Science , vol.266 , pp. 1045-1047
    • Miyazaki, T.1
  • 78
    • 0029875230 scopus 로고    scopus 로고
    • Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
    • Friedmann MC, Migone TS, Russell SM, Leonard WJ. Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc Natl Acad Sci USA 1996;93:2077-2082.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2077-2082
    • Friedmann, M.C.1    Migone, T.S.2    Russell, S.M.3    Leonard, W.J.4
  • 79
    • 0029115522 scopus 로고
    • Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15
    • Johnston JA, et al. Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. Proc Natl Acad Sci USA 1995;92:8705-8709.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8705-8709
    • Johnston, J.A.1
  • 80
    • 0032212138 scopus 로고    scopus 로고
    • The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc
    • Lord JD, McIntosh BC, Greenberg PD, Nelson BH. The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc. J Immunol 1998;161:4627-4633.
    • (1998) J Immunol , vol.161 , pp. 4627-4633
    • Lord, J.D.1    McIntosh, B.C.2    Greenberg, P.D.3    Nelson, B.H.4
  • 81
    • 0033199317 scopus 로고    scopus 로고
    • Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
    • Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999;11:281-288.
    • (1999) Immunity , vol.11 , pp. 281-288
    • Van Parijs, L.1    Refaeli, Y.2    Lord, J.D.3    Nelson, B.H.4    Abbas, A.K.5    Baltimore, D.6
  • 82
    • 0033082138 scopus 로고    scopus 로고
    • Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
    • Moriggl R, et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 1999;10:249-259.
    • (1999) Immunity , vol.10 , pp. 249-259
    • Moriggl, R.1
  • 83
    • 0034675853 scopus 로고    scopus 로고
    • MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly
    • Holmstrom TH, et al. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly. EMBO J 2000;19:5418-5428.
    • (2000) EMBO J , vol.19 , pp. 5418-5428
    • Holmstrom, T.H.1
  • 84
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999;286:1358-1362.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 85
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1
  • 86
    • 0032560514 scopus 로고    scopus 로고
    • Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation
    • Scheid MP, Duronio V. Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation. Proc Natl Acad Sci USA 1998;95:7439-7444.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7439-7444
    • Scheid, M.P.1    Duronio, V.2
  • 87
    • 0032747134 scopus 로고    scopus 로고
    • Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase
    • Scheid MP, Schubert KM, Duronio V. Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase. J Biol Chem 1999;274:31108-31113.
    • (1999) J Biol Chem , vol.274 , pp. 31108-31113
    • Scheid, M.P.1    Schubert, K.M.2    Duronio, V.3
  • 88
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997;278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 89
    • 0030585701 scopus 로고    scopus 로고
    • Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis
    • Radvanyi LG, Shi Y, Mills GB, Miller RG. Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis. Cell Immunol 1996;170:260-273.
    • (1996) Cell Immunol , vol.170 , pp. 260-273
    • Radvanyi, L.G.1    Shi, Y.2    Mills, G.B.3    Miller, R.G.4
  • 90
    • 0027182225 scopus 로고
    • Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
    • Boehme SA, Lenardo MJ. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur J Immunol 1993;23:1552-1560.
    • (1993) Eur J Immunol , vol.23 , pp. 1552-1560
    • Boehme, S.A.1    Lenardo, M.J.2
  • 91
    • 0030588710 scopus 로고    scopus 로고
    • Human T cells require IL-2 but not G1/S transition to acquire susceptibility to Fas-mediated apoptosis
    • Fournel S, Genestier L, Robinet E, Flacher M, Revillard JP. Human T cells require IL-2 but not G1/S transition to acquire susceptibility to Fas-mediated apoptosis. J Immunol 1996;157:4309-4315.
    • (1996) J Immunol , vol.157 , pp. 4309-4315
    • Fournel, S.1    Genestier, L.2    Robinet, E.3    Flacher, M.4    Revillard, J.P.5
  • 94
    • 0033790128 scopus 로고    scopus 로고
    • Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells
    • Kirchhoff S, Muller WW, Li-Weber M, Krammer PH. Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells. Eur J Immunol 2000;30:2765-2774.
    • (2000) Eur J Immunol , vol.30 , pp. 2765-2774
    • Kirchhoff, S.1    Muller, W.W.2    Li-Weber, M.3    Krammer, P.H.4
  • 95
    • 0032055478 scopus 로고    scopus 로고
    • Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells
    • Hitoski Y, et al. Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity 1998;8:461-471.
    • (1998) Immunity , vol.8 , pp. 461-471
    • Hitoski, Y.1
  • 97
    • 0036140143 scopus 로고    scopus 로고
    • Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection
    • Zhou S, Ou R, Huang L, Moskophidis D. Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection. J Virol 2002;76:829-840.
    • (2002) J Virol , vol.76 , pp. 829-840
    • Zhou, S.1    Ou, R.2    Huang, L.3    Moskophidis, D.4
  • 98
    • 0035213014 scopus 로고    scopus 로고
    • Activation-induced cell death of human T-cell subsets is mediated by Fas and granzyme B but is independent of TNF-alpha
    • Gorak-Stolinska P, Truman JP, Kemeny DM, Noble A. Activation-induced cell death of human T-cell subsets is mediated by Fas and granzyme B but is independent of TNF-alpha. J Leukoc Biol 2001;70:756-766.
    • (2001) J Leukoc Biol , vol.70 , pp. 756-766
    • Gorak-Stolinska, P.1    Truman, J.P.2    Kemeny, D.M.3    Noble, A.4
  • 99
    • 0022996750 scopus 로고
    • IL-2 addiction: Withdrawal of growth factor activates a suicide program in dependent T cells
    • Duke RC, Cohen JJ. IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res 1986;5:289-299.
    • (1986) Lymphokine Res , vol.5 , pp. 289-299
    • Duke, R.C.1    Cohen, J.J.2
  • 100
    • 0025786164 scopus 로고
    • bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser A, Harris AW, Cory S. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 1991;67:889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 102
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999;286:1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1
  • 103
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999;3:287-296.
    • (1999) Mol Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 104
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
    • Hildeman DA, et al. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 2002;16:759-767.
    • (2002) Immunity , vol.16 , pp. 759-767
    • Hildeman, D.A.1
  • 105
    • 0033151622 scopus 로고    scopus 로고
    • Reactive oxygen species regulate activation-induced T cell apoptosis
    • Hildeman DA, et al. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity 1999;10:735-744.
    • (1999) Immunity , vol.10 , pp. 735-744
    • Hildeman, D.A.1
  • 106
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
    • Van Parijs L, Peterson DA, Abbas AK. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 1998;8:265-274.
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 107
    • 0036170440 scopus 로고    scopus 로고
    • Activation and inhibition of lymphocytes by costimulation
    • Frauwirth KA, Thompson CB. Activation and inhibition of lymphocytes by costimulation. J Clin Invest 2002;109:295-299.
    • (2002) J Clin Invest , vol.109 , pp. 295-299
    • Frauwirth, K.A.1    Thompson, C.B.2
  • 108
    • 0033151995 scopus 로고    scopus 로고
    • CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation
    • Gonsky R, Deem RL, Lee DH, Chen A, Targan SR. CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation. J Immunol 1999;162:6621-6629.
    • (1999) J Immunol , vol.162 , pp. 6621-6629
    • Gonsky, R.1    Deem, R.L.2    Lee, D.H.3    Chen, A.4    Targan, S.R.5
  • 109
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995;3:87-98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1
  • 110
    • 0030010956 scopus 로고    scopus 로고
    • Signaling through CD28/CTLA-4 family receptors: Puzzling participation of phosphatidylinositol-3 kinase
    • Hutchcroft JE, Bierer BE. Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase. J Immunol 1996;156:4071-4074.
    • (1996) J Immunol , vol.156 , pp. 4071-4074
    • Hutchcroft, J.E.1    Bierer, B.E.2
  • 111
    • 0032055502 scopus 로고    scopus 로고
    • Networking Rho family GTPases in lymphocytes
    • Reif K, Cantrell DA. Networking Rho family GTPases in lymphocytes. Immunity 1998;8:395-401.
    • (1998) Immunity , vol.8 , pp. 395-401
    • Reif, K.1    Cantrell, D.A.2
  • 112
    • 0035319244 scopus 로고    scopus 로고
    • A point mutation in CD28 distinguishes proliferative signals from survival signals
    • Okkenhaug K, et al. A point mutation in CD28 distinguishes proliferative signals from survival signals. Nat Immunol 2001;2:325-332.
    • (2001) Nat Immunol , vol.2 , pp. 325-332
    • Okkenhaug, K.1
  • 113
    • 0035869402 scopus 로고    scopus 로고
    • Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo
    • Harada Y, et al. Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo. J Immunol 2001;166:3797-3803.
    • (2001) J Immunol , vol.166 , pp. 3797-3803
    • Harada, Y.1
  • 114
    • 0037015038 scopus 로고    scopus 로고
    • Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
    • Diehn M, et al. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci USA 2002;99:11796-11801.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11796-11801
    • Diehn, M.1
  • 115
    • 0032529317 scopus 로고    scopus 로고
    • Distinct regulation of T-cell death by CD28 depending on both its aggregation and T-cell receptor triggering: A role for Fas-FasL
    • Collette Y, Benziane A, Razanajaona D, Olive D. Distinct regulation of T-cell death by CD28 depending on both its aggregation and T-cell receptor triggering: a role for Fas-FasL. Blood 1998;92:1350-1363.
    • (1998) Blood , vol.92 , pp. 1350-1363
    • Collette, Y.1    Benziane, A.2    Razanajaona, D.3    Olive, D.4
  • 116
    • 0037025948 scopus 로고    scopus 로고
    • CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly
    • Jones RG, et al. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. J Exp Med 2002;196:335-348.
    • (2002) J Exp Med , vol.196 , pp. 335-348
    • Jones, R.G.1
  • 119
    • 0034162511 scopus 로고    scopus 로고
    • Qualitative changes accompany memory T cell generation: Faster, more effective responses at lower doses of antigen
    • Rogers PR, Dubey C, Swain SL. Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol 2000;164:2338-2346.
    • (2000) J Immunol , vol.164 , pp. 2338-2346
    • Rogers, P.R.1    Dubey, C.2    Swain, S.L.3
  • 120
    • 0033542458 scopus 로고    scopus 로고
    • Modelling T-cell memory by genetic marking of memory T cells in vivo
    • Jacob J, Baltimore D. Modelling T-cell memory by genetic marking of memory T cells in vivo. Nature 1999;399:593-597.
    • (1999) Nature , vol.399 , pp. 593-597
    • Jacob, J.1    Baltimore, D.2
  • 121
    • 0034885547 scopus 로고    scopus 로고
    • CD4(+) T cell effectors can become memory cells with high efficiency and without further division
    • Hu H, Huston G, Duso D, Lepak N, Roman E, Swain SL. CD4(+) T cell effectors can become memory cells with high efficiency and without further division. Nat Immunol 2001;2:705-710.
    • (2001) Nat Immunol , vol.2 , pp. 705-710
    • Hu, H.1    Huston, G.2    Duso, D.3    Lepak, N.4    Roman, E.5    Swain, S.L.6
  • 122
    • 0033548496 scopus 로고    scopus 로고
    • Linear differentiation of cytotoxic effectors into memory T lymphocytes
    • Opferman Jr, Ober BT, Ashton-Rickardt PG. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 1999;283:1745-1748.
    • (1999) Science , vol.283 , pp. 1745-1748
    • Opferman, Jr.1    Ober, B.T.2    Ashton-Rickardt, P.G.3
  • 123
    • 0027158798 scopus 로고
    • Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
    • Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993;362:758-761.
    • (1993) Nature , vol.362 , pp. 758-761
    • Moskophidis, D.1    Lechner, F.2    Pircher, H.3    Zinkernagel, R.M.4
  • 124
    • 0027476846 scopus 로고
    • Immunological memory
    • Gray D. Immunological memory. Annu Rev Immunol 1993;11:49-77.
    • (1993) Annu Rev Immunol , vol.11 , pp. 49-77
    • Gray, D.1
  • 125
    • 0032589687 scopus 로고    scopus 로고
    • Class II-independent generation of CD4 memory T cells from effectors
    • Swain SL, Hu H, Huston G. Class II-independent generation of CD4 memory T cells from effectors. Science 1999;286:1381-1383.
    • (1999) Science , vol.286 , pp. 1381-1383
    • Swain, S.L.1    Hu, H.2    Huston, G.3
  • 127
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771-780.
    • (2000) J Exp Med , vol.191 , pp. 771-780
    • Kennedy, M.K.1
  • 128
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, Boone DL, Chai S, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3
  • 131
    • 0037124328 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J Exp Med 2002;195:1533-1539.
    • (2002) J Exp Med , vol.195 , pp. 1533-1539
    • Kieper, W.C.1
  • 134
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • Jameson SC. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol 2002;2:547-556.
    • (2002) Nat Rev Immunol , vol.2 , pp. 547-556
    • Jameson, S.C.1
  • 135
    • 0034548714 scopus 로고    scopus 로고
    • TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity
    • Kirchhoff S, Muller WW, Krueger A, Schmitz I, Krammer PH. TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity. J Immunol 2000;165:6293-6300.
    • (2000) J Immunol , vol.165 , pp. 6293-6300
    • Kirchhoff, S.1    Muller, W.W.2    Krueger, A.3    Schmitz, I.4    Krammer, P.H.5
  • 136
    • 0033178616 scopus 로고    scopus 로고
    • Primed T cells are more resistant to Fas-mediated activation-induced cell death than naïve T cells
    • Inaba M, Kurasawa K, Mamura M, Kumano K, Saito Y, Iwamoto I. Primed T cells are more resistant to Fas-mediated activation-induced cell death than naïve T cells. J Immunol 1999;163:1315-1320.
    • (1999) J Immunol , vol.163 , pp. 1315-1320
    • Inaba, M.1    Kurasawa, K.2    Mamura, M.3    Kumano, K.4    Saito, Y.5    Iwamoto, I.6
  • 137
    • 0033567061 scopus 로고    scopus 로고
    • Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells
    • Ludewig B, Oehen S, Barchiesi F, Schwendener RA, Hengartner H, Zinkernagel RM. Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells. J Immunol 1999;163:1839-1844.
    • (1999) J Immunol , vol.163 , pp. 1839-1844
    • Ludewig, B.1    Oehen, S.2    Barchiesi, F.3    Schwendener, R.A.4    Hengartner, H.5    Zinkernagel, R.M.6
  • 138
    • 0344188227 scopus 로고    scopus 로고
    • On the role of antigen in maintaining cytotoxic T-cell memory
    • Kundig TM, et al. On the role of antigen in maintaining cytotoxic T-cell memory. Proc Natl Acad Sci USA 1996;93:9716-9723.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9716-9723
    • Kundig, T.M.1
  • 139
  • 141
    • 0036682492 scopus 로고    scopus 로고
    • Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential
    • Dunne PJ, et al. Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential. Blood 2002;100:933-940.
    • (2002) Blood , vol.100 , pp. 933-940
    • Dunne, P.J.1
  • 142
    • 1442342360 scopus 로고    scopus 로고
    • Following the development of a CD4 T cell response in vivo: From activation to memory formation
    • Garcia S, DiSanto J, Stockinger B. Following the development of a CD4 T cell response in vivo: from activation to memory formation. Immunity 1999;11:163-171.
    • (1999) Immunity , vol.11 , pp. 163-171
    • Garcia, S.1    DiSanto, J.2    Stockinger, B.3
  • 143
    • 0027369794 scopus 로고
    • A possible role for bcl-2 in regulating T-cell memory - A 'balancing act' between cell death and survival
    • Akbar AN, Salmon M, Savill J, Janossy G. A possible role for bcl-2 in regulating T-cell memory - a 'balancing act' between cell death and survival. Immunol Today 1993;14:526-532.
    • (1993) Immunol Today , vol.14 , pp. 526-532
    • Akbar, A.N.1    Salmon, M.2    Savill, J.3    Janossy, G.4
  • 144
    • 0033056851 scopus 로고    scopus 로고
    • Interferon-beta mediates stromal cell rescue of T cells from apoptosis
    • Pilling D, et al. Interferon-beta mediates stromal cell rescue of T cells from apoptosis. Eur J Immunol 1999;29:1041-1050.
    • (1999) Eur J Immunol , vol.29 , pp. 1041-1050
    • Pilling, D.1
  • 145
    • 0344931885 scopus 로고    scopus 로고
    • Expression of the transcription factor lung Kruppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo
    • Schober SL, Kuo CT, Schluns KS, Lefrancois L, Leiden JM, Jameson SC. Expression of the transcription factor lung Kruppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. J Immunol 1999;163:3662-3667.
    • (1999) J Immunol , vol.163 , pp. 3662-3667
    • Schober, S.L.1    Kuo, C.T.2    Schluns, K.S.3    Lefrancois, L.4    Leiden, J.M.5    Jameson, S.C.6


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