메뉴 건너뛰기




Volumn 10, Issue 11, 2000, Pages 640-648

The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords


EID: 18744425429     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00512-1     Document Type: Article
Times cited : (508)

References (37)
  • 1
    • 0030965162 scopus 로고    scopus 로고
    • Cell death induction by TNF: A matter of self control
    • Wallach D. Cell death induction by TNF: a matter of self control. Trends Biochem Sci. 22:1997;107-109.
    • (1997) Trends Biochem Sci , vol.22 , pp. 107-109
    • Wallach, D.1
  • 2
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 3
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 5
    • 0030970013 scopus 로고    scopus 로고
    • Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
    • Thome M.et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature. 386:1997;517-521.
    • (1997) Nature , vol.386 , pp. 517-521
    • Thome, M.1
  • 6
    • 12644286556 scopus 로고    scopus 로고
    • Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- And TNFR1-induced apoptosis
    • Bertin J.et al. Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. Proc Natl Acad Sci USA. 94:1997;1172-1176.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1172-1176
    • Bertin, J.1
  • 7
    • 0031726359 scopus 로고    scopus 로고
    • Inhibition of Fas death signals by FLIPs
    • Tschopp J., Irmler M., Thome M. Inhibition of Fas death signals by FLIPs. Curr Opin Immunol. 10:1998;552-558.
    • (1998) Curr Opin Immunol , vol.10 , pp. 552-558
    • Tschopp, J.1    Irmler, M.2    Thome, M.3
  • 8
    • 1842367285 scopus 로고    scopus 로고
    • Apoptosis: Placing death under control
    • Wallach D. Apoptosis: placing death under control. Nature. 388:1997;123.
    • (1997) Nature , vol.388 , pp. 123
    • Wallach, D.1
  • 9
    • 0032472916 scopus 로고    scopus 로고
    • A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
    • Newton K., Harris A.W., Bath M.L., Smith K.G.C., Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 17:1998;706-718.
    • (1998) EMBO J , vol.17 , pp. 706-718
    • Newton, K.1    Harris, A.W.2    Bath, M.L.3    Smith, K.G.C.4    Strasser, A.5
  • 11
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
    • Zhang J., Cado D., Chen A., Kabra N.H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature. 392:1998;296-300.
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 12
    • 7144263731 scopus 로고    scopus 로고
    • FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
    • Yeh W.C.et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science. 279:1998;1954-1958.
    • (1998) Science , vol.279 , pp. 1954-1958
    • Yeh, W.C.1
  • 13
    • 0028048353 scopus 로고
    • T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A
    • Anel A., Buferne M., Boyer C., Schmitt V.A., Golstein P. T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. Eur J Immunol. 24:1994;2469-2476.
    • (1994) Eur J Immunol , vol.24 , pp. 2469-2476
    • Anel, A.1    Buferne, M.2    Boyer, C.3    Schmitt, V.A.4    Golstein, P.5
  • 15
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40- And Fas (CD95)-ligands modulated by the B cell antigen receptor
    • Rathmell J.C., Townsend S.E., Xu J.C., Flavell R.A., Goodnow C.C. Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell. 87:1996;319-329.
    • (1996) Cell , vol.87 , pp. 319-329
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.C.3    Flavell, R.A.4    Goodnow, C.C.5
  • 16
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner T.et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature. 373:1995;441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1
  • 17
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • Schneider P., Holler N., Bodmer J.L., Hahne M., Frei K., Fontana A., Tschopp J. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med. 187:1998;1205-1213.
    • (1998) J Exp Med , vol.187 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.L.3    Hahne, M.4    Frei, K.5    Fontana, A.6    Tschopp, J.7
  • 18
    • 0027936441 scopus 로고
    • AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes
    • Rincon M., Flavell R.A. AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J. 13:1994;4370-4381.
    • (1994) EMBO J , vol.13 , pp. 4370-4381
    • Rincon, M.1    Flavell, R.A.2
  • 19
    • 0031034051 scopus 로고    scopus 로고
    • Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells
    • Rincon M., Flavell R.A. Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol Cell Biol. 17:1997;1522-1534.
    • (1997) Mol Cell Biol , vol.17 , pp. 1522-1534
    • Rincon, M.1    Flavell, R.A.2
  • 20
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • Irmler M.et al. Inhibition of death receptor signals by cellular FLIP. Nature. 388:1997;190-195.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1
  • 21
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C., Schmitz I., Krammer P.H., Peter M.E. The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem. 274:1999;1541-1548.
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 22
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent Apo-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., Peter M.E. Cytotoxicity-dependent Apo-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14:1995;5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Krammer, P.H.6    Peter, M.E.7
  • 23
    • 0032541670 scopus 로고    scopus 로고
    • IKAP is a scaffold protein of the IkappaB kinase complex
    • Cohen L., Henzel W.J., Baeuerle P.A. IKAP is a scaffold protein of the IkappaB kinase complex. Nature. 395:1998;292-296.
    • (1998) Nature , vol.395 , pp. 292-296
    • Cohen, L.1    Henzel, W.J.2    Baeuerle, P.A.3
  • 24
    • 0030685825 scopus 로고    scopus 로고
    • IKK-1 and IKK-2: Cytokine-activated IkappaB kinases essential for NF-kappaB activation
    • Mercurio F.et al. IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science. 278:1997;860-866.
    • (1997) Science , vol.278 , pp. 860-866
    • Mercurio, F.1
  • 25
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao Z., Henzel W.J., Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 271:1996;1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 26
  • 27
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- And caspase-related inducer of apoptosis
    • Shu H.B., Halpin D.R., Goeddel D.V. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 6:1997;751-763.
    • (1997) Immunity , vol.6 , pp. 751-763
    • Shu, H.B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 28
    • 0024025869 scopus 로고
    • The structure of the human CD2 gene and its expression in transgenic mice
    • Lang G., Wotton D., Owen M.J., Sewell W.A., Brown M.H., Mason D.Y.et al. The structure of the human CD2 gene and its expression in transgenic mice. EMBO J. 7:1988;1675-1682.
    • (1988) EMBO J , vol.7 , pp. 1675-1682
    • Lang, G.1    Wotton, D.2    Owen, M.J.3    Sewell, W.A.4    Brown, M.H.5    Mason, D.Y.6
  • 29
    • 0032974475 scopus 로고    scopus 로고
    • Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells
    • Bossi G., Griffiths G.M. Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells. Nat Med. 5:1999;90-96.
    • (1999) Nat Med , vol.5 , pp. 90-96
    • Bossi, G.1    Griffiths, G.M.2
  • 30
    • 0033386808 scopus 로고    scopus 로고
    • Caspase activation is required for T cell proliferation
    • Kennedy N.J., Kataoka T., Tschopp J., Budd R.C. Caspase activation is required for T cell proliferation. J Exp Med. 190:1999;1891-1896.
    • (1999) J Exp Med , vol.190 , pp. 1891-1896
    • Kennedy, N.J.1    Kataoka, T.2    Tschopp, J.3    Budd, R.C.4
  • 31
    • 0025735114 scopus 로고
    • Elevated production of interferon-gamma and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression
    • Budd R.C., Schumacher J.H., Winslow G., Mosmann T.R. Elevated production of interferon-gamma and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression. Eur J Immunol. 21:1991;1081-1084.
    • (1991) Eur J Immunol , vol.21 , pp. 1081-1084
    • Budd, R.C.1    Schumacher, J.H.2    Winslow, G.3    Mosmann, T.R.4
  • 32
    • 0028913463 scopus 로고
    • Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor
    • Aggarwal B.B., Singh S., LaPushin R., Totpal K. Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor. FEBS Lett. 364:1995;5-8.
    • (1995) FEBS Lett , vol.364 , pp. 5-8
    • Aggarwal, B.B.1    Singh, S.2    Lapushin, R.3    Totpal, K.4
  • 33
    • 0033523670 scopus 로고    scopus 로고
    • Immune escape of tumors In vivo by expression of cellular FLICE-inhibitory protein
    • Medema J.P., de Jong J., van Hall T., Melief C.J., Offringa R. Immune escape of tumors In vivo by expression of cellular FLICE-inhibitory protein. J Exp Med. 190:1999;1033-1038.
    • (1999) J Exp Med , vol.190 , pp. 1033-1038
    • Medema, J.P.1    De Jong, J.2    Van Hall, T.3    Melief, C.J.4    Offringa, R.5
  • 34
    • 0032143986 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
    • Varfolomeev E.E.et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9:1998;267-276.
    • (1998) Immunity , vol.9 , pp. 267-276
    • Varfolomeev, E.E.1
  • 35
    • 7344220967 scopus 로고    scopus 로고
    • Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD95 (Fas/Apo-1) receptor complex
    • Rasper D., Vaillancourt J., Hadano S., Houtzager V., Seiden I., Keen L.et al. Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD95 (Fas/Apo-1) receptor complex. Cell Death Differ. 5:1998;271-288.
    • (1998) Cell Death Differ , vol.5 , pp. 271-288
    • Rasper, D.1    Vaillancourt, J.2    Hadano, S.3    Houtzager, V.4    Seiden, I.5    Keen, L.6
  • 37
    • 0031055415 scopus 로고    scopus 로고
    • Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras
    • de Rooij J., Bos J.L. Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene. 14:1997;623-625.
    • (1997) Oncogene , vol.14 , pp. 623-625
    • De Rooij, J.1    Bos, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.