Qualitative changes accompany memory T cell generation: Faster, more effective, responses at lower doses of antigen

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2338-2346

  Rogers, Paul R ^a   Dubey, Caroline ^b   Swain, Susan L ^c  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b SANOFI   (France)

^c TRUDEAU INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD44V ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; PADGEM PROTEIN; PEPTIDE DERIVATIVE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIVISION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IMMUNOSTIMULATION; INTERFERON PRODUCTION; LYMPHOCYTE PROLIFERATION; MALE; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE;

EID: 0034162511     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2338     Document Type: Article

References (53)

1. Sprent, J., and D. F. Tough. 1994. Lymphocyte life-span and memory. Science 265:1395.
2. Swain, S. L., R. W. Dutton, and L. M. Bradley. 1998. T cell memory. Annu. Rev. Immunol. 16:201.
3. Swain, S. L., M. Croft, C. Dubey, L. Haynes, P. Rogers, X. Zhang, and L. M. Bradley. 1996. From naive to memory T cells. Immunol. Rev. 150:143.
4. Mackay, C. R. 1993. Immunological memory. Adv. Immunol. 53:217.
5. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
6. Bradley, L. M., D. D. Duncan, K. Yoshimoto, and S. L. Swain. 1993. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J. Immunol. 150:3119.
7. + T-cell memory determined by clonal burst size. Nature 369:652.
8. Lau, L., B. D. Jamieson, T. Somasundaram, and R. Ahmed. 1994. Cytotoxic T-cell memory without antigen. Nature 369:648.
9. Swain, S. L. 1994. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1:543.
10. + T-cells differing in CD45R expression. J. Immunol. 149:2300.
11. +) human T cells to multiple receptor-mediated stimuli but augmentation of responses by co-stimuli. Eur. J. Immunol. 20:1111.
12. Mullbacher, A., and K. Flynn. 1996. Aspects of cytotoxic T cell memory. Immunol. Rev. 150:113.
13. Bruno, L., J. Kirberg, and H. von Boehmer. 1995. On the cellular basis of immunological T cell memory. Immunity 2:37.
14. Byrne, J. A., J. L. Butler, and M. D. Cooper. 1988. Differential activation requirements for virgin and memory T cells. J. Immunol. 141:3249.
15. + T cells are hyperreactive to antigenic challenge in vitro. J. Exp. Med. 184:2141.
16. Croft, J., L. M. Bradley, and S. L. Swain. 1994. Naive versus memory CD4 T cell response to antigen: memory cells are less dependent on accessory cell costimulation and can respond to many APC types including resting B cells. J. Immunol. 152:2675.
17. Dubey, C., M. Croft, and S. L. Swain. 1996. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J. Immunol. 157:3280.
18. + T cells: ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J. Immunol. 155:45.
19. Croft, M. 1994. Activation of naive, memory and effector T cells. Curr. Opin. Immunol. 6:431.
20. + T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 335:229.
21. + T cells in vitro: characteristics and antigen-presenting cell requirements. J. Exp. Med. 176:1431.
22. Linton, P. J., L. Haynes, N. R. Klinman, and S. L. Swain. 1996. Antigen-independent changes in naive CD4 T cells with aging. J. Exp. Med. 184:1891.
23. Zhang, X., L. Giangreco, H. E. Broome, C. M. Dargan, and S. L. Swain. 1995. Control of CD4 effector fate: transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J. Exp. Med. 182:699.
24. Gudmundsdottir, H., A. D. Wells, and L. A. Turka. 1999. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity. J. Immunol. 162:5212.
25. Weston, S. A., and C. R. Parish. 1990. New fluorescent dyes for lymphocyte migration studies: analysis by flow cytometry and fluorescence microscopy. J. Immunol. Methods 133:87.
26. Karasuyama, H., and F. Melchars. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4, 5 using modified cDNA vectors. Eur. J. Immunol. 18:97.
27. Rogers, P. R., H. M. Grey, and M. Croft. 1998. Modulation of naive CD4 T cell activation with altered peptide ligands: The nature of the peptide and presentation in the context of costimulation are critical for a sustained response. J. Immunol. 160:3698.
28. + thymocytes by T-cell receptor peptide antagonists. Proc. Natl. Acad. Sci. USA 91:4057.
29. Balomenos, D., R. S. Balderas, K. P. Mulvany, J. Kaye, D. Kono, and A. N. Theofilopoulos. 1995. Incomplete T cell receptor Vβ allelic exclusion and dual Vβ-expressing cells. J. Immunol. 155:3308.
30. Swain, S. L., H. Hu, and G. Huston. 1999. Class II-independent generation of CD4 memory T cells from effectors. Science 286:1381.
31. + T lymphocytes in vivo. J. Immunol. 162:766.
32. Akbar, A. N., M. Salmon, and G. Janossy. 1991. The synergy between naive and memory T cells during activation. Immunol. Today 12:184.
33. Beverley, P. 1991. Immunological memory in T cells. Curr. Opin. Immunol. 3:355.
34. Cerwenka, A., L. L. Carter, J. B. Reome, S. L. Swain, and R. W. Dutton. 1998. In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J. Immunol. 161:97.
35. Reay, P. A., R. M. Kantor, and M. M. Davis. 1994. Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103). J. Immunol. 152:3946.
36. + T cells. J. Exp. Med. 185:2133.
37. Cella, M., F. Sallusto, and A. Lanzavecchia. 1997. Origin, maturation, and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 9:10.
38. Sanders, M. E., M. W. Makgoba, S. O. Sharrow, D. Stephany, T. A. Springer, H. A. Young, and S. Shaw. 1988. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHLI, CDw29, and Pgp-1) and have enhanced IFN-γ production. J. Immunol. 140:1401.
39. - helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon γ. J. Exp. Med. 174:547.
40. Altman, J. D., P. A. H. Moss, P. J. R. Goulder, D. H. Barouch, M. G. McHeyzer-Williams, J. I. Bell, A. J. McMichael, and M. M. Davis. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274:94.
41. Jenkins, M. K. 1994. The ups and downs of T cell costimulation. Immunity 1:443.
42. Tanchot, C., F. A. Lemonnier, B. Perarnau, A. A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276:2057.
43. Agarwal, S., and A. Rao. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765.
44. + T cells. J. Exp. Med. 188:103.
45. Swain, S. L., L. M. Bradley, M. Croft, S. Tonkonogy, G. Atkins, A. D. Weinberg, D. D. Duncan, S. M. Hedrick, R. W. Dutton, and G. Huston. 1991. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol. Rev. 123:115.
46. + T cell subsets: lymphokine secretion of memory cells and of effector cells that develop from precursors. J. Immunol. 144:1788.
47. Croft, M., and S. L. Swain. 1995. Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J. Immunol. 154:4269.
48. + T cell response. J. Immunol. 161:674.
49. Farber, D. L., O. Acuto, and K. Boltomly. 1997. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur. J. Immunol. 27:2094.
50. Keamey, E. R., K. A. Pape. D. Y. Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
51. Doherty, P. C., S. Hou, and R. A. Tripp. 1994. T-cell memory to viruses. Curr. Opin. Immunol. 6:545.
52. Matzinger, P. 1994. Memories are made of this? Nature 369:605.
53. McHeyzer-Williams, M. G., and M. M. Davis. 1995. Antigen-specific development of primary and memory T cells in vivo. Science 268:106.