Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice

Nature Medicine

Volumn 2, Issue 1, 1996, Pages 80-86

  Lacronique, Virginie ^a   Mignon, Alexandre ^a,b   Fabre, Monique ^c   Viollet, Benoit ^a   Rouquet, Nicolas ^a   Molina, Thierry ^a   Porteu, Arlette ^a   Henrion, Alexandra ^a   Bouscary, Didier ^a   Varlet, Paule ^a   Joulin, Virginie ^a   Kahn, Axel ^a  

^a INSTITUT COCHIN   (France)

^b Université Paris Descartes   (France)

^c BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; LIVER FAILURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; VIRUS HEPATITIS;

ANIMALS; ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; GTP-BINDING PROTEINS; HEPATIC ENCEPHALOPATHY; HUMANS; LIVER; MICE; MICE, INBRED CBA; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENES;

ANIMALIA; MUS MUSCULUS;

EID: 13344279418     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0196-80     Document Type: Article

References (6)

1. Thompson, C.B. Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462 (1995).
2. Nagata, S. & Golstein, P. The Fas death factor. Science 267, 1449-1456 (1995).
3. Suda, T. & Nagata, S. Purification and characterization of the Fas-ligand that induces apoptosis. J. Exp. Med. 179, 873-879 (1994).
4. Itoh, N. et al. The polypeptide encoded by the cDNA for the human cell surface antigen Fas can mediate apoptosis. Cell 66, 233-243 (1991).
5. Trauth, B.C. et al. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245, 301-304 (1989).
6. 2+-independent T cell-mediated cytotoxicity. J. Exp. Med. 177, 195-200 (1993).