메뉴 건너뛰기




Volumn 161, Issue 9, 1998, Pages 4627-4633

The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2 RECEPTOR; ONCOPROTEIN; PROTEIN BCL 2;

EID: 0032212138     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (75)

References (59)
  • 1
    • 0023907493 scopus 로고
    • Interleukin 2: Inception, impact and implications
    • Smith, K. A. 1988. Interleukin 2: inception, impact and implications. Science 240:1169.
    • (1988) Science , vol.240 , pp. 1169
    • Smith, K.A.1
  • 3
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and fas in T cell apoptosis and peripheral tolerance
    • Van Parijs, L., A. Ibraghimov, and A. K. Abbas. 1996. The roles of costimulation and fas in T cell apoptosis and peripheral tolerance. Immunity 4:321.
    • (1996) Immunity , vol.4 , pp. 321
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 4
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2Rα)-deficient T cells expressing a transgenic antigen receptor
    • Van Parijs, L., A. Biuckians, A. Ibraghimov, F. W. Alt, D. M. Willerford, and A. K. Abbas. 1997. Functional responses and apoptosis of CD25 (IL-2Rα)-deficient T cells expressing a transgenic antigen receptor. J. Immunol. 158:3738.
    • (1997) J. Immunol. , vol.158 , pp. 3738
    • Van Parijs, L.1    Biuckians, A.2    Ibraghimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 6
    • 0025255538 scopus 로고
    • Deregulated bcl-2 expression selectively prolongs survival of growth factor deprived hematopoietic cell lines
    • Nunez, G., L. London, D. Hockenbery, M. Alexander, J. P. McKearn, and S. J. Korsmeyer. 1990. Deregulated bcl-2 expression selectively prolongs survival of growth factor deprived hematopoietic cell lines. J. Immunol. 144:3602.
    • (1990) J. Immunol. , vol.144 , pp. 3602
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5    Korsmeyer, S.J.6
  • 8
    • 0029046693 scopus 로고
    • Expression of bcl-2, bcl-x, and box after T cell activation and IL-2 withdrawal
    • Broome, H. E., C. M. Dargan, S. Krajewski, and J. C. Reed. 1995. Expression of bcl-2, bcl-x, and box after T cell activation and IL-2 withdrawal. J. Immunol. 155:2311.
    • (1995) J. Immunol. , vol.155 , pp. 2311
    • Broome, H.E.1    Dargan, C.M.2    Krajewski, S.3    Reed, J.C.4
  • 9
    • 0027537118 scopus 로고
    • Suppression of apoptosis in a cytotoxic T-cell line by interleukin-2-mediated gene transcription and deregulated expression of the protooncogene bcl-2
    • Deng, G., and E. R. Podack. 1993. Suppression of apoptosis in a cytotoxic T-cell line by interleukin-2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc. Natl. Acad. Sci. USA 90:2189.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2189
    • Deng, G.1    Podack, E.R.2
  • 10
    • 0027394657 scopus 로고
    • The IL-2, IL-2 receptor system: A current overview
    • Taniguchi, T., and Y. Minami. 1993. The IL-2, IL-2 receptor system: a current overview. Cell 73:5.
    • (1993) Cell , vol.73 , pp. 5
    • Taniguchi, T.1    Minami, Y.2
  • 12
    • 0028244396 scopus 로고
    • Involvement of the Jak-3 janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
    • Witthuhn, B. A., O. Silvennoinen, O. Miura, K. S. Lai, C. Cwik, E. T. Liu, and J. N. Ihle. 1994. Involvement of the Jak-3 janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 370:153.
    • (1994) Nature , vol.370 , pp. 153
    • Witthuhn, B.A.1    Silvennoinen, O.2    Miura, O.3    Lai, K.S.4    Cwik, C.5    Liu, E.T.6    Ihle, J.N.7
  • 18
    • 0028799457 scopus 로고
    • Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
    • Thomis, D. C, C. B. Gurniak, E. Tivol, A. H. Sharpe, and L. J. Berg. 1995. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 270:794.
    • (1995) Science , vol.270 , pp. 794
    • Thomis, D.C.1    Gurniak, C.B.2    Tivol, E.3    Sharpe, A.H.4    Berg, L.J.5
  • 19
    • 0029115353 scopus 로고
    • Critical role of the interleukin 2 (IL-2) receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction
    • Kawahara, A., Y. Minami, T. Miyazaki, J. N. Ihle, and T. Taniguchi. 1995. Critical role of the interleukin 2 (IL-2) receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction. Proc. Natl. Acad. Sci. USA 92:8724.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8724
    • Kawahara, A.1    Minami, Y.2    Miyazaki, T.3    Ihle, J.N.4    Taniguchi, T.5
  • 20
    • 0029875230 scopus 로고    scopus 로고
    • Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
    • Friedmann, M. C., T. S. Migone, S. M. Russell, and W. J. Leonard. 1996. Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc. Natl. Acad. Sci. USA 93:2077.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2077
    • Friedmann, M.C.1    Migone, T.S.2    Russell, S.M.3    Leonard, W.J.4
  • 21
    • 0029655803 scopus 로고    scopus 로고
    • A membrane-proximal region of the interleukin-2 receptor γ c chain sufficient for Jak kinase activation and induction of proliferation in T cells
    • Nelson, B. H., J. D. Lord, and P. D. Greenberg. 1996. A membrane-proximal region of the interleukin-2 receptor γ c chain sufficient for Jak kinase activation and induction of proliferation in T cells. Mol. Cell. Biol. 16:309.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 309
    • Nelson, B.H.1    Lord, J.D.2    Greenberg, P.D.3
  • 22
    • 0029124056 scopus 로고
    • Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the β chain and non-tyrosine residues of the γ c chain
    • Goldsmith, M. A., S. Y. Lai, W. Xu, M. C. Amaral, E. S. Kuczek, L. J. Parent, G. B. Mills, K. L. Tarr, G. D. Longmore, and W. C. Greene. 1995. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the β chain and non-tyrosine residues of the γ c chain. J. Biol. Chem. 270: 21729.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21729
    • Goldsmith, M.A.1    Lai, S.Y.2    Xu, W.3    Amaral, M.C.4    Kuczek, E.S.5    Parent, L.J.6    Mills, G.B.7    Tarr, K.L.8    Longmore, G.D.9    Greene, W.C.10
  • 25
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill, C. S., and R. Treisman. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199.
    • (1995) Cell , vol.80 , pp. 199
    • Hill, C.S.1    Treisman, R.2
  • 27
    • 0030962699 scopus 로고    scopus 로고
    • She contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes
    • Harmer, S. L., and A. L. DeFranco. 1997. She contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes. Mol. Cell. Biol. 17:4087.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4087
    • Harmer, S.L.1    DeFranco, A.L.2
  • 31
    • 0030049783 scopus 로고    scopus 로고
    • Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
    • Bennet, A. M., S. F. Hausdorff, A. M. O'Reilly, R. M. Freeman, and B. G. Neel. 1996. Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol. Cell. Biol. 16:1189.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1189
    • Bennet, A.M.1    Hausdorff, S.F.2    O'Reilly, A.M.3    Freeman, R.M.4    Neel, B.G.5
  • 32
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of Stat3 in anti-apoptosis
    • Fukada, T., M. Hibi, Y. Yamanaka, M. Takahashi-Tezuka, M. Fujitani, T. Yamaguchi, K. Nakajima, and T. Hirano. 1996. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of Stat3 in anti-apoptosis. Immunity 5:449.
    • (1996) Immunity , vol.5 , pp. 449
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitani, M.5    Yamaguchi, T.6    Nakajima, K.7    Hirano, T.8
  • 33
    • 0028219966 scopus 로고
    • An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth
    • Keegan, A. D., K. Nelms, M. White, L. Wang, J. H. Pierce, and W. E. Paul. 1994. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. Cell 76:811.
    • (1994) Cell , vol.76 , pp. 811
    • Keegan, A.D.1    Nelms, K.2    White, M.3    Wang, L.4    Pierce, J.H.5    Paul, W.E.6
  • 34
    • 0028876283 scopus 로고
    • Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells
    • Johnston, J. A., L. Wang, E. P. Hanson, X. Sun, M. F. White, S. A. Oakes, J. H. Pierce, and J. J. O'Shea. 1995. Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. J. Biol. Chem. 270:28527.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28527
    • Johnston, J.A.1    Wang, L.2    Hanson, E.P.3    Sun, X.4    White, M.F.5    Oakes, S.A.6    Pierce, J.H.7    O'Shea, J.J.8
  • 36
    • 0342820096 scopus 로고    scopus 로고
    • Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway
    • Gonzalez-Garcia, A., I. Merida, C. Martinez-A., and A. C. Carrera. 1997. Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 272:10220.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10220
    • Gonzalez-Garcia, A.1    Merida, I.2    Martinez-A, C.3    Carrera, A.C.4
  • 37
    • 0028286628 scopus 로고
    • Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
    • Nelson, B. H., J. D. Lord, and P. D. Greenberg. 1994. Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 369:333.
    • (1994) Nature , vol.369 , pp. 333
    • Nelson, B.H.1    Lord, J.D.2    Greenberg, P.D.3
  • 38
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S., H. Hunt, R. Horton, J. Pullen, and L. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51.
    • (1989) Gene , vol.77 , pp. 51
    • Ho, S.1    Hunt, H.2    Horton, R.3    Pullen, J.4    Pease, L.5
  • 39
    • 0031055524 scopus 로고    scopus 로고
    • Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ c chain for Janus kinase activation leading to T cell proliferation
    • Nelson, B. H., B. C. McIntosh, L. L. Rosencrans, and P. D. Greenberg. 1997. Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ c chain for Janus kinase activation leading to T cell proliferation. Prof. Natl. Acad. Sci. USA 94:1878.
    • (1997) Prof. Natl. Acad. Sci. USA , vol.94 , pp. 1878
    • Nelson, B.H.1    McIntosh, B.C.2    Rosencrans, L.L.3    Greenberg, P.D.4
  • 41
    • 0029813118 scopus 로고    scopus 로고
    • Distinct residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity
    • Gaffen, S. L., S. Y. Lai, M. Ha, X. Liu, L. Hennighausen, W. C. Greene, and M. A. Goldsmith. 1996. Distinct residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity. J. Biol. Chem. 271:21381.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21381
    • Gaffen, S.L.1    Lai, S.Y.2    Ha, M.3    Liu, X.4    Hennighausen, L.5    Greene, W.C.6    Goldsmith, M.A.7
  • 42
    • 0029892399 scopus 로고    scopus 로고
    • Suppression of interleukin-3-induced gene expression by a C-terminal truncated STATS: Role of STATS in proliferation
    • Mui, A. L., H. Wakao, T. Kinoshita, T. Kitamura, and A. Miyajima. 1996. Suppression of interleukin-3-induced gene expression by a C-terminal truncated STATS: role of STATS in proliferation. EMBO J. 15:2425.
    • (1996) EMBO J. , vol.15 , pp. 2425
    • Mui, A.L.1    Wakao, H.2    Kinoshita, T.3    Kitamura, T.4    Miyajima, A.5
  • 43
    • 0028859279 scopus 로고
    • Protein modules and signalling networks
    • Pawson, T. 1995. Protein modules and signalling networks. Nature 373:573.
    • (1995) Nature , vol.373 , pp. 573
    • Pawson, T.1
  • 44
    • 0027257445 scopus 로고
    • A kinase-independent function of Lck in potentiating antigen-specific T cell activation
    • Xu, H., and D. R. Littman. 1993. A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74:633.
    • (1993) Cell , vol.74 , pp. 633
    • Xu, H.1    Littman, D.R.2
  • 46
    • 0030899807 scopus 로고    scopus 로고
    • Tyrosine phosphorylation sites at amino acids 239 and 240 of She are involved in epidermal growth factor-induced mitogenic signalling that is distinct from ras/mitogen-activated protein kinase activation
    • Gotoh, N., M. Toyoda, and M. Shibuya. 1997. Tyrosine phosphorylation sites at amino acids 239 and 240 of She are involved in epidermal growth factor-induced mitogenic signalling that is distinct from ras/mitogen-activated protein kinase activation. Mol. Cell. Biol. 17:1824.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1824
    • Gotoh, N.1    Toyoda, M.2    Shibuya, M.3
  • 47
    • 0029978202 scopus 로고    scopus 로고
    • The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3.4.5-trisphosphate 5-phosphatase
    • Damen, J. E., L. Liu, P. Rosten, R. K. Humphries, A. B. Jefferson, P. W. Majerus, and G. Krystal. 1996. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3.4.5-trisphosphate 5-phosphatase. Proc. Natl. Acad. Sci. USA 93:1689.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1689
    • Damen, J.E.1    Liu, L.2    Rosten, P.3    Humphries, R.K.4    Jefferson, A.B.5    Majerus, P.W.6    Krystal, G.7
  • 48
    • 0028596158 scopus 로고
    • An alternative to SH2 domains for binding tyrosine phosphorylated proteins
    • Kavanaugh, W. M., and L. T. Williams. 1994. An alternative to SH2 domains for binding tyrosine phosphorylated proteins. Science 266:1862.
    • (1994) Science , vol.266 , pp. 1862
    • Kavanaugh, W.M.1    Williams, L.T.2
  • 49
    • 0029033866 scopus 로고
    • Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells
    • Kinoshita, T., T. Yokota, K. Arai, and A. Miyajima. 1995. Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene 10:2207.
    • (1995) Oncogene , vol.10 , pp. 2207
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3    Miyajima, A.4
  • 50
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land, H., L. F. Parada, and R. A. Weinberg. 1983. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304:596.
    • (1983) Nature , vol.304 , pp. 596
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 51
    • 0029910522 scopus 로고    scopus 로고
    • A novel pathway from phosphorylation of tyrosine residues 239/240 of She, contributing to suppress apoptosis by IL-3
    • Gotoh, N., A. Tojo, and M. Shibuya. 1996. A novel pathway from phosphorylation of tyrosine residues 239/240 of She, contributing to suppress apoptosis by IL-3. EMBO J. 15:6197.
    • (1996) EMBO J. , vol.15 , pp. 6197
    • Gotoh, N.1    Tojo, A.2    Shibuya, M.3
  • 52
    • 0027326012 scopus 로고
    • Characterization of A1, a novel hematopoietic-specific early-response gene with sequence similarity to bcl-2
    • Lin, E. Y., A. Orlofsky, M. S. Berger, and M. B. Prystowsky. 1993. Characterization of A1, a novel hematopoietic-specific early-response gene with sequence similarity to bcl-2. J. Immunol. 151:1979.
    • (1993) J. Immunol. , vol.151 , pp. 1979
    • Lin, E.Y.1    Orlofsky, A.2    Berger, M.S.3    Prystowsky, M.B.4
  • 53
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai, Z. N., C. L. Milliman, and S. J. Korsmeyer. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609.
    • (1993) Cell , vol.74 , pp. 609
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 56
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • Del Peso, L., M. Gonzalez-Garcia, C. Page, R. Herrera, and G. Nunez. 1997. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687.
    • (1997) Science , vol.278 , pp. 687
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 57
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed, N. N., H. H. Grimes, A. Bellacosa, T. O. Chan, and P. N. Tsichlis. 1997. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA 94:3627.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3627
    • Ahmed, N.N.1    Grimes, H.H.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 58
    • 0028837491 scopus 로고
    • Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors
    • Kinoshita, T., T. Yokota, K. I. Arai, and A. Miyajima. 1995. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J. 14:266.
    • (1995) EMBO J. , vol.14 , pp. 266
    • Kinoshita, T.1    Yokota, T.2    Arai, K.I.3    Miyajima, A.4
  • 59
    • 0028170658 scopus 로고
    • ras activation blocks proliferation but not differentiation of IL-3-dependent myeloid cells
    • ras activation blocks proliferation but not differentiation of IL-3-dependent myeloid cells. J. Biol. Chem. 269:24602.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24602
    • Okuda, K.1    Ernst, T.J.2    Griffin, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.