-
2
-
-
0032411142
-
Alterations in cyclindependent kinase 2 function during differentiation of primary human keratinocytes
-
Alani RM, Hasskarl J, Munger K (1998). Alterations in cyclindependent kinase 2 function during differentiation of primary human keratinocytes. Mol Carcinog 23:226-233.
-
(1998)
Mol Carcinog
, vol.23
, pp. 226-233
-
-
Alani, R.M.1
Hasskarl, J.2
Munger, K.3
-
3
-
-
0029657768
-
WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine
-
WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. Cell Growth Differ 7:893-901.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 893-901
-
-
Alpan, R.S.1
Pardee, A.B.2
-
4
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi LD, Lowe SW, Brugarolas J, Jacks T (1996). Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J 15:3693-3701.
-
(1996)
EMBO J
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
6
-
-
0035359505
-
Exploiting cancer cell cycling for selective protection of normal cells
-
Blagosklonny MV, Pardee AB (2001). Exploiting cancer cell cycling for selective protection of normal cells. Cancer Res 61:4301-4305.
-
(2001)
Cancer Res
, vol.61
, pp. 4301-4305
-
-
Blagosklonny, M.V.1
Pardee, A.B.2
-
9
-
-
0027406396
-
Different levels of v-Ha-ras p21 expression in primary keratinocytes transformed with Harvey sarcoma virus correlate with benign versus malignant behavior
-
Brissette JL, Missero C, Yuspa SH, Dotto GP (1993). Different levels of v-Ha-ras p21 expression in primary keratinocytes transformed with Harvey sarcoma virus correlate with benign versus malignant behavior. Mol Carcinog 7:21-25.
-
(1993)
Mol Carcinog
, vol.7
, pp. 21-25
-
-
Brissette, J.L.1
Missero, C.2
Yuspa, S.H.3
Dotto, G.P.4
-
10
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ (1995). Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
11
-
-
0033514441
-
Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation
-
Brugarolas J, Moberg K, Boyd SD, Taya Y, Jacks T, Lees JA (1999). Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation. Proc Natl Acad Sci USA 96:1002-1007.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1002-1007
-
-
Brugarolas, J.1
Moberg, K.2
Boyd, S.D.3
Taya, Y.4
Jacks, T.5
Lees, J.A.6
-
12
-
-
0032078707
-
p21(WAF1/Cip1) retards the growth of human squamous cell carcinomas in vivo
-
Cardinali M, Jakus J, Shah S, Ensley JF, Robbins KC, Yeudall WA (1998). p21(WAF1/Cip1) retards the growth of human squamous cell carcinomas in vivo. Oral Oncol 34:211-218.
-
(1998)
Oral Oncol
, vol.34
, pp. 211-218
-
-
Cardinali, M.1
Jakus, J.2
Shah, S.3
Ensley, J.F.4
Robbins, K.C.5
Yeudall, W.A.6
-
13
-
-
0032511893
-
Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21
-
Cayrol C, Ducommun B (1998). Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21. Oncogene 17:2437-2444.
-
(1998)
Oncogene
, vol.17
, pp. 2437-2444
-
-
Cayrol, C.1
Ducommun, B.2
-
14
-
-
0033606852
-
Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs
-
Chang BD, Xuan Y, Broude EV, Zhu H, Schott B, Fang J, et al. (1999). Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 18:4808-4818.
-
(1999)
Oncogene
, vol.18
, pp. 4808-4818
-
-
Chang, B.D.1
Xuan, Y.2
Broude, E.V.3
Zhu, H.4
Schott, B.5
Fang, J.6
-
15
-
-
0034689774
-
p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells
-
Chang BD, Broude EV, Fang J, Kalinichenko TV, Abdryashitov R, Poole JC, et al. (2000a). p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells. Oncogene 19:2165-2170.
-
(2000)
Oncogene
, vol.19
, pp. 2165-2170
-
-
Chang, B.D.1
Broude, E.V.2
Fang, J.3
Kalinichenko, T.V.4
Abdryashitov, R.5
Poole, J.C.6
-
16
-
-
0034635914
-
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
-
Chang BD, Watanabe K, Broude EV, Fang J, Poole JC, Kalinichenko TV, et al. (2000b). Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases. Proc Natl Acad Sci USA 97:4291-4296.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4291-4296
-
-
Chang, B.D.1
Watanabe, K.2
Broude, E.V.3
Fang, J.4
Poole, J.C.5
Kalinichenko, T.V.6
-
17
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J, Jackson PK, Kirschner MW, Dutta A (1995). Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374:386-388.
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
18
-
-
0029808931
-
Effects of ectopic overexpression of p21(WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells
-
Chen J, Willingham T, Shuford M, Bruce D, Rushing E, Smith Y, et al. (1996). Effects of ectopic overexpression of p21(WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells. Oncogene 13:1395-1403.
-
(1996)
Oncogene
, vol.13
, pp. 1395-1403
-
-
Chen, J.1
Willingham, T.2
Shuford, M.3
Bruce, D.4
Rushing, E.5
Smith, Y.6
-
19
-
-
0027585508
-
Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene
-
Cheng C, Tennenbaum T, Dempsey PJ, Coffey RJ, Yuspa SH, Dlugosz AA (1993). Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene. Cell Growth Differ 4:317-327.
-
(1993)
Cell Growth Differ
, vol.4
, pp. 317-327
-
-
Cheng, C.1
Tennenbaum, T.2
Dempsey, P.J.3
Coffey, R.J.4
Yuspa, S.H.5
Dlugosz, A.A.6
-
20
-
-
0033559264
-
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
-
Cheng M, Olivier P, Diehl JA, Fero M, Roussel MF, Roberts JM, et al. (1999). The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J 18:1571-1583.
-
(1999)
EMBO J
, vol.18
, pp. 1571-1583
-
-
Cheng, M.1
Olivier, P.2
Diehl, J.A.3
Fero, M.4
Roussel, M.F.5
Roberts, J.M.6
-
22
-
-
0030818761
-
Involvement of the cell cycle inhibitor CIP1/WAF1 in lung alveolar epithelial cell growth arrest induced by glucocorticoids
-
Corroyer S, Nabeyrat E, Clement A (1997). Involvement of the cell cycle inhibitor CIP1/WAF1 in lung alveolar epithelial cell growth arrest induced by glucocorticoids. Endocrinology 138:3677-3685.
-
(1997)
Endocrinology
, vol.138
, pp. 3677-3685
-
-
Corroyer, S.1
Nabeyrat, E.2
Clement, A.3
-
23
-
-
0031586030
-
Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells
-
Courtois SJ, Woodworth CD, Degreef H, Garmyn M (1997). Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells. Exp Cell Res 233:135-144.
-
(1997)
Exp Cell Res
, vol.233
, pp. 135-144
-
-
Courtois, S.J.1
Woodworth, C.D.2
Degreef, H.3
Garmyn, M.4
-
24
-
-
0030866223
-
Multiple pathways control cell growth and transformation: Overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1
-
Cox LS (1997). Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1. J Pathol 183:134-140.
-
(1997)
J Pathol
, vol.183
, pp. 134-140
-
-
Cox, L.S.1
-
25
-
-
0029073142
-
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
-
Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF (1995a). Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 92:5545-5549.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5545-5549
-
-
Datto, M.B.1
Li, Y.2
Panus, J.F.3
Howe, D.J.4
Xiong, Y.5
Wang, X.F.6
-
26
-
-
0028829465
-
Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter
-
Datto MB, Yu Y, Wang XF (1995b). Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270:28623-28628.
-
(1995)
J Biol Chem
, vol.270
, pp. 28623-28628
-
-
Datto, M.B.1
Yu, Y.2
Wang, X.F.3
-
28
-
-
0033598444
-
Control of E2F activity by p21Waf1/Cip1
-
Delavaine L, La Thangue NB (1999). Control of E2F activity by p21Waf1/Cip1. Oncogene 18:5381-5392.
-
(1999)
Oncogene
, vol.18
, pp. 5381-5392
-
-
Delavaine, L.1
La Thangue, N.B.2
-
29
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
Deng C, Zhang P, Harper JW, Elledge SJ, Leder P (1995). Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
31
-
-
0033979731
-
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
-
Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, et al. (2000). Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20:1436-1447.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1436-1447
-
-
Dickson, M.A.1
Hahn, W.C.2
Ino, Y.3
Ronfard, V.4
Wu, J.Y.5
Weinberg, R.A.6
-
32
-
-
0029162341
-
Isolation and utilization of epidermal keratinocytes for oncogene research
-
Dlugosz AA, Glick AB, Tennenbaum T, Weinberg WC, Yuspa SH (1995). Isolation and utilization of epidermal keratinocytes for oncogene research. Meth Enzymol 254:3-20.
-
(1995)
Meth Enzymol
, vol.254
, pp. 3-20
-
-
Dlugosz, A.A.1
Glick, A.B.2
Tennenbaum, T.3
Weinberg, W.C.4
Yuspa, S.H.5
-
33
-
-
0028823416
-
In vivo gene therapy with p53 or p21 adenovirus for prostate cancer
-
Eastham JA, Hall SJ, Sehgal I, Wang J, Timme TL, Yang G, et al. (1995). In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res 55:5151-5155.
-
(1995)
Cancer Res
, vol.55
, pp. 5151-5155
-
-
Eastham, J.A.1
Hall, S.J.2
Sehgal, I.3
Wang, J.4
Timme, T.L.5
Yang, G.6
-
34
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
35
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
El Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, et al. (1994). WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 54:1169-1174.
-
(1994)
Cancer Res
, vol.54
, pp. 1169-1174
-
-
El Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
-
37
-
-
0029963169
-
p16 inhibition of transformed and primary squamous epithelial cells
-
Enders GH, Koh J, Missero C, Rustgi AK, Harlow E (1996). p16 inhibition of transformed and primary squamous epithelial cells. Oncogene 12:1239-1245.
-
(1996)
Oncogene
, vol.12
, pp. 1239-1245
-
-
Enders, G.H.1
Koh, J.2
Missero, C.3
Rustgi, A.K.4
Harlow, E.5
-
38
-
-
0030757636
-
Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer
-
Erber R, Klein W, Andl T, Enders C, Born AI, Conradt C, et al. (1997). Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer. Int J Cancer 74:383-389.
-
(1997)
Int J Cancer
, vol.74
, pp. 383-389
-
-
Erber, R.1
Klein, W.2
Andl, T.3
Enders, C.4
Born, A.I.5
Conradt, C.6
-
39
-
-
0028980376
-
Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition
-
Fan Z, Lu Y, Wu X, DeBlasio A, Koff A, Mendelsohn J (1995). Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition. J Cell Biol 131:235-242.
-
(1995)
J Cell Biol
, vol.131
, pp. 235-242
-
-
Fan, Z.1
Lu, Y.2
Wu, X.3
DeBlasio, A.4
Koff, A.5
Mendelsohn, J.6
-
40
-
-
0033864297
-
Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity
-
Franklin DS, Godfrey VL, O'Brien DA, Deng C, Xiong Y (2000). Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity. Mol Cell Biol 20:6147-6158.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6147-6158
-
-
Franklin, D.S.1
Godfrey, V.L.2
O'Brien, D.A.3
Deng, C.4
Xiong, Y.5
-
41
-
-
0028089871
-
The epidermis: Rising to the surface
-
Fuchs E, Byrne C (1994). The epidermis: rising to the surface. Curr Opin Genet Dev 4:725-736.
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 725-736
-
-
Fuchs, E.1
Byrne, C.2
-
42
-
-
0033080402
-
Transcriptional regulation of the p21((WAF1/CIP1)) gene
-
Gartel AL, Tyner AL (1999). Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp Cell Res 246:280-289.
-
(1999)
Exp Cell Res
, vol.246
, pp. 280-289
-
-
Gartel, A.L.1
Tyner, A.L.2
-
43
-
-
0035836706
-
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
-
Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, et al. (2001). Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci USA 98:4510-4515.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4510-4515
-
-
Gartel, A.L.1
Ye, X.2
Goufman, E.3
Shianov, P.4
Hay, N.5
Najmabadi, F.6
-
44
-
-
0029021714
-
Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor
-
Goubin F, Ducommun B (1995). Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor. Oncogene 10:2281-2287.
-
(1995)
Oncogene
, vol.10
, pp. 2281-2287
-
-
Goubin, F.1
Ducommun, B.2
-
45
-
-
0017756282
-
Terminal differentiation of cultured human epidermal cells
-
Green H (1977). Terminal differentiation of cultured human epidermal cells. Cell 11:405-416.
-
(1977)
Cell
, vol.11
, pp. 405-416
-
-
Green, H.1
-
46
-
-
0029782220
-
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha
-
Greenhalgh DA, Wang XJ, Donehower LA, Roop DR (1996a). Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res 56:4413-4423.
-
(1996)
Cancer Res
, vol.56
, pp. 4413-4423
-
-
Greenhalgh, D.A.1
Wang, X.J.2
Donehower, L.A.3
Roop, D.R.4
-
47
-
-
0030112254
-
Multistage epidermal carcinogenesis in transgenic mice: Cooperativity and paradox
-
Greenhalgh DA, Wang XJ, Roop DR (1996b). Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox. J Investig Dermatol Symp Proc 1:162-176.
-
(1996)
J Investig Dermatol Symp Proc
, vol.1
, pp. 162-176
-
-
Greenhalgh, D.A.1
Wang, X.J.2
Roop, D.R.3
-
48
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
Gu Y, Turck CW, Morgan DO (1993). Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366:707-710.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
49
-
-
0033541394
-
UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner
-
Haapajarvi T, Kivinen L, Heiskanen A, des BC, Datto MB, Wang XF, et al. (1999). UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner. Exp Cell Res 248:272-279.
-
(1999)
Exp Cell Res
, vol.248
, pp. 272-279
-
-
Haapajarvi, T.1
Kivinen, L.2
Heiskanen, A.3
Des, B.C.4
Datto, M.B.5
Wang, X.F.6
-
50
-
-
0031841384
-
IARC database of p53 gene mutations in human tumors and cell lines: Updated compilation, revised formats and new visualisation tools
-
Hainaut P, Hernandez T, Robinson A, Rodriguez-Tome P, Flores T, Hollstein M, et al. (1998). IARC database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools. Nucleic Acids Res 26:205-213.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 205-213
-
-
Hainaut, P.1
Hernandez, T.2
Robinson, A.3
Rodriguez-Tome, P.4
Flores, T.5
Hollstein, M.6
-
51
-
-
0028941483
-
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
-
Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, et al. (1995). Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267:1018-1021.
-
(1995)
Science
, vol.267
, pp. 1018-1021
-
-
Halevy, O.1
Novitch, B.G.2
Spicer, D.B.3
Skapek, S.X.4
Rhee, J.5
Hannon, G.J.6
-
52
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993). The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
53
-
-
0035725471
-
Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexes
-
Harvat BL, Jetten AM (2001). Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexes. J Invest Dermatol 117:1274-1281.
-
(2001)
J Invest Dermatol
, vol.117
, pp. 1274-1281
-
-
Harvat, B.L.1
Jetten, A.M.2
-
54
-
-
0031750613
-
Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation
-
Harvat BL, Wang A, Seth P, Jetten AM (1998). Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation. J Cell Sci 111:1185-1196.
-
(1998)
J Cell Sci
, vol.111
, pp. 1185-1196
-
-
Harvat, B.L.1
Wang, A.2
Seth, P.3
Jetten, A.M.4
-
55
-
-
0030614671
-
The role of p27kip1 in the in vitro differentiation of murine keratinocytes
-
Hauser PJ, Agrawal D, Flanagan M, Pledger WJ (1997). The role of p27kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ 8:203-211.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 203-211
-
-
Hauser, P.J.1
Agrawal, D.2
Flanagan, M.3
Pledger, W.J.4
-
56
-
-
0018865014
-
Calcium regulation of growth and differentiation of mouse epidermal cells in culture
-
Hennings H, Michael D, Cheng C, Steinert P, Holbrook K, Yuspa SH (1980). Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19:245-254.
-
(1980)
Cell
, vol.19
, pp. 245-254
-
-
Hennings, H.1
Michael, D.2
Cheng, C.3
Steinert, P.4
Holbrook, K.5
Yuspa, S.H.6
-
57
-
-
0022179539
-
Induction of papillomas with a high probability of conversion to malignancy
-
Hennings H, Shores R, Mitchell P, Spangler EF, Yuspa SH (1985). Induction of papillomas with a high probability of conversion to malignancy. Carcinogenesis 6:1607-1610.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1607-1610
-
-
Hennings, H.1
Shores, R.2
Mitchell, P.3
Spangler, E.F.4
Yuspa, S.H.5
-
58
-
-
0028827848
-
Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase
-
Herzinger T, Funk JO, Hillmer K, Eick D, Wolf DA, Kind P (1995). Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase. Oncogene 11:2151-2156.
-
(1995)
Oncogene
, vol.11
, pp. 2151-2156
-
-
Herzinger, T.1
Funk, J.O.2
Hillmer, K.3
Eick, D.4
Wolf, D.A.5
Kind, P.6
-
59
-
-
0033544887
-
The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta
-
Hu PP, Shen X, Huang D, Liu Y, Counter C, Wang XF (1999). The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta. J Biol Chem 274:35381-35387.
-
(1999)
J Biol Chem
, vol.274
, pp. 35381-35387
-
-
Hu, P.P.1
Shen, X.2
Huang, D.3
Liu, Y.4
Counter, C.5
Wang, X.F.6
-
60
-
-
0030013561
-
Growth inhibitory concentrations of EGF induce p21 (WAF1/Cip1) and alter cell cycle control in squamous carcinoma cells
-
Jakus J, Yeudall WA (1996). Growth inhibitory concentrations of EGF induce p21 (WAF1/Cip1) and alter cell cycle control in squamous carcinoma cells. Oncogene 12:2369-2376.
-
(1996)
Oncogene
, vol.12
, pp. 2369-2376
-
-
Jakus, J.1
Yeudall, W.A.2
-
61
-
-
0029031949
-
The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells
-
Jiang H, Lin J, Su ZZ, Herlyn M, Kerbel RS, Weissman BE, et al. (1995). The melanoma differentiation-associated gene mda-6, which encodes the cyclin -dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene 10:1855-1864.
-
(1995)
Oncogene
, vol.10
, pp. 1855-1864
-
-
Jiang, H.1
Lin, J.2
Su, Z.Z.3
Herlyn, M.4
Kerbel, R.S.5
Weissman, B.E.6
-
62
-
-
0034616116
-
Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription
-
Kitaura H, Shinshi M, Uchikoshi Y, Ono T, Iguchi-Ariga SM, Ariga H (2000). Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription. J Biol Chem 275:10477-10483.
-
(2000)
J Biol Chem
, vol.275
, pp. 10477-10483
-
-
Kitaura, H.1
Shinshi, M.2
Uchikoshi, Y.3
Ono, T.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
63
-
-
0035800746
-
Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein
-
Koutsodontis G, Tentes I, Papakosta P, Moustakas A, Kardassis D (2001). Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein. J Biol Chem 276:29116-29125.
-
(2001)
J Biol Chem
, vol.276
, pp. 29116-29125
-
-
Koutsodontis, G.1
Tentes, I.2
Papakosta, P.3
Moustakas, A.4
Kardassis, D.5
-
64
-
-
0035503697
-
WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype
-
WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype. Cancer Res 61:7754-7762.
-
(2001)
Cancer Res
, vol.61
, pp. 7754-7762
-
-
Kramer, D.L.1
Chang, B.D.2
Chen, Y.3
Diegelman, P.4
Alm, K.5
Black, A.R.6
-
65
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
LaBaer J, Garrett MD, Stevenson LF, Slingerland JM, Sandhu C, Chou HS, et al. (1997). New functional activities for the p21 family of CDK inhibitors. Genes Dev 11:847-862.
-
(1997)
Genes Dev
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
Chou, H.S.6
-
66
-
-
0030796989
-
WAF1 and G1 cellcycle arrest by the chemopreventive agent apigenin
-
WAF1 and G1 cellcycle arrest by the chemopreventive agent apigenin. Mol Carcinog 19:74-82.
-
(1997)
Mol Carcinog
, vol.19
, pp. 74-82
-
-
Lepley, D.M.1
Pelling, J.C.2
-
67
-
-
0028898203
-
Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect
-
Li CY, Suardet L, Little JB (1995). Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect. J Biol Chem 270:4971-4974.
-
(1995)
J Biol Chem
, vol.270
, pp. 4971-4974
-
-
Li, C.Y.1
Suardet, L.2
Little, J.B.3
-
68
-
-
0030088038
-
Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage
-
Li R, Hannon GJ, Beach D, Stillman B (1996). Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Curr Biol 6:189-199.
-
(1996)
Curr Biol
, vol.6
, pp. 189-199
-
-
Li, R.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
69
-
-
0037192852
-
AKT/PKB phosphorylation of p21Cip1/WAF1 enhances protein stability of p21Cip1/WAF1 and promotes cell survival
-
Li Y, Dowbenko D, Lasky LA (2002). AKT/PKB phosphorylation of p21Cip1/WAF1 enhances protein stability of p21Cip1/WAF1 and promotes cell survival. J Biol Chem 27:11352-11361.
-
(2002)
J Biol Chem
, vol.27
, pp. 11352-11361
-
-
Li, Y.1
Dowbenko, D.2
Lasky, L.A.3
-
70
-
-
0029928180
-
Analysis of wild-type and mutant p21WAF-1 gene activities
-
Lin J, Reichner C, Wu X, Levine AJ (1996). Analysis of wild-type and mutant p21WAF-1 gene activities. Mol Cell Biol 16:1786-1793.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1786-1793
-
-
Lin, J.1
Reichner, C.2
Wu, X.3
Levine, A.J.4
-
71
-
-
0029955958
-
Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation
-
Liu M, Iavarone A, Freedman LP (1996). Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. J Biol Chem 271:31723-31728.
-
(1996)
J Biol Chem
, vol.271
, pp. 31723-31728
-
-
Liu, M.1
Iavarone, A.2
Freedman, L.P.3
-
74
-
-
0029666504
-
Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: Relationship of dysfunction to immortality and neoplasia
-
Loughran O, Malliri A, Owens D, Gallimore PH, Stanley MA, Ozanne B, et al. (1996). Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to immortality and neoplasia. Oncogene 13:561-568.
-
(1996)
Oncogene
, vol.13
, pp. 561-568
-
-
Loughran, O.1
Malliri, A.2
Owens, D.3
Gallimore, P.H.4
Stanley, M.A.5
Ozanne, B.6
-
75
-
-
0029063745
-
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
-
Luo Y, Hurwitz J, Massagué J (1995). Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 375:159-161.
-
(1995)
Nature
, vol.375
, pp. 159-161
-
-
Luo, Y.1
Hurwitz, J.2
Massagué, J.3
-
76
-
-
0028963841
-
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
-
Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, et al. (1995). p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 9:935-944.
-
(1995)
Genes Dev
, vol.9
, pp. 935-944
-
-
Macleod, K.F.1
Sherry, N.2
Hannon, G.3
Beach, D.4
Tokino, T.5
Kinzler, K.6
-
78
-
-
0033552953
-
Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation
-
Martinez LA, Chen Y, Fischer SM, Conti CJ (1999). Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation. Oncogene 18:397-406.
-
(1999)
Oncogene
, vol.18
, pp. 397-406
-
-
Martinez, L.A.1
Chen, Y.2
Fischer, S.M.3
Conti, C.J.4
-
79
-
-
0032510327
-
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
-
McConnell BB, Starborg M, Brookes S, Peters G (1998). Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts. Curr Biol 8:351-354.
-
(1998)
Curr Biol
, vol.8
, pp. 351-354
-
-
McConnell, B.B.1
Starborg, M.2
Brookes, S.3
Peters, G.4
-
80
-
-
0028236846
-
Induction of WAF1/CIP1 by a p53-independent pathway
-
Michieli P, Chedid M, Lin D, Pierce JH, Mercer WE, Givol D (1994). Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res 54:3391-3395.
-
(1994)
Cancer Res
, vol.54
, pp. 3391-3395
-
-
Michieli, P.1
Chedid, M.2
Lin, D.3
Pierce, J.H.4
Mercer, W.E.5
Givol, D.6
-
81
-
-
0029020945
-
Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation
-
Missero C, Calautti E, Eckner R, Chin J, Tsai LH, Livingston DM, et al. (1995). Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci USA 92:5451-5455.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5451-5455
-
-
Missero, C.1
Calautti, E.2
Eckner, R.3
Chin, J.4
Tsai, L.H.5
Livingston, D.M.6
-
82
-
-
0029658030
-
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
-
Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP (1996). The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev 10:3065-3075.
-
(1996)
Genes Dev
, vol.10
, pp. 3065-3075
-
-
Missero, C.1
Di Cunto, F.2
Kiyokawa, H.3
Koff, A.4
Dotto, G.P.5
-
83
-
-
0032920581
-
WAF1/CIP1 expression and induces S-phase entry in 12-Otetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells
-
WAF1/CIP1 expression and induces S-phase entry in 12-Otetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells. Cell Growth Differ 10:223-230.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 223-230
-
-
Mitchell, K.O.1
El Deiry, W.S.2
-
84
-
-
0033152226
-
Role of the alternative INK4A proteins in human keratinocyte senescence: Evidence for the specific inactivation of p16INK4A upon immortalization
-
Munro J, Stott FJ, Vousden KH, Peters G, Parkinson EK (1999). Role of the alternative INK4A proteins in human keratinocyte senescence: evidence for the specific inactivation of p16INK4A upon immortalization. Cancer Res 59:2516-2521.
-
(1999)
Cancer Res
, vol.59
, pp. 2516-2521
-
-
Munro, J.1
Stott, F.J.2
Vousden, K.H.3
Peters, G.4
Parkinson, E.K.5
-
85
-
-
0033565263
-
A p21(Waf1/Cip1)carboxyl-terminal peptide exhibited cyclin-dependent kinase-inhibitory activity and cytotoxicity when introduced into human cells
-
Mutoh M, Lung FD, Long YQ, Roller PP, Sikorski RS, O'Connor PM (1999). A p21(Waf1/Cip1)carboxyl-terminal peptide exhibited cyclin-dependent kinase-inhibitory activity and cytotoxicity when introduced into human cells. Cancer Res 59:3480-3488.
-
(1999)
Cancer Res
, vol.59
, pp. 3480-3488
-
-
Mutoh, M.1
Lung, F.D.2
Long, Y.Q.3
Roller, P.P.4
Sikorski, R.S.5
O'Connor, P.M.6
-
86
-
-
0028982946
-
The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition
-
Nakanishi M, Robetorye RS, Pereira-Smith OM, Smith JR (1995). The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition. J Biol Chem 270:17060-17063.
-
(1995)
J Biol Chem
, vol.270
, pp. 17060-17063
-
-
Nakanishi, M.1
Robetorye, R.S.2
Pereira-Smith, O.M.3
Smith, J.R.4
-
87
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda A, Ning Y, Venable SF, Pereira-Smith OM, Smith JR (1994). Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211:90-98.
-
(1994)
Exp Cell Res
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
88
-
-
0035941206
-
The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis
-
Paramio JM, Segrelles C, Ruiz S, Martin-Caballero J, Page A, Martinez J, et al. (2001). The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis. J Biol Chem 276:44203-44211.
-
(2001)
J Biol Chem
, vol.276
, pp. 44203-44211
-
-
Paramio, J.M.1
Segrelles, C.2
Ruiz, S.3
Martin-Caballero, J.4
Page, A.5
Martinez, J.6
-
89
-
-
0034815687
-
p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization
-
Park JW, Jang MA, Lee YH, Passaniti A, Kwon TK (2001). p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization. Biochem Biophys Res Commun 280:244-248.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 244-248
-
-
Park, J.W.1
Jang, M.A.2
Lee, Y.H.3
Passaniti, A.4
Kwon, T.K.5
-
90
-
-
0028986639
-
p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells
-
Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, et al. (1995). p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267:1024-1027.
-
(1995)
Science
, vol.267
, pp. 1024-1027
-
-
Parker, S.B.1
Eichele, G.2
Zhang, P.3
Rawls, A.4
Sands, A.T.5
Bradley, A.6
-
91
-
-
0030614504
-
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
-
Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ (1997). Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 275:523-527.
-
(1997)
Science
, vol.275
, pp. 523-527
-
-
Perkins, N.D.1
Felzien, L.K.2
Betts, J.C.3
Leung, K.4
Beach, D.H.5
Nabel, G.J.6
-
92
-
-
0033584257
-
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis
-
Philipp J, Vo K, Gurley KE, Seidel K, Kemp CJ (1999). Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis. Oncogene 18:4689-4698.
-
(1999)
Oncogene
, vol.18
, pp. 4689-4698
-
-
Philipp, J.1
Vo, K.2
Gurley, K.E.3
Seidel, K.4
Kemp, C.J.5
-
93
-
-
0028179669
-
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
-
Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massagué J, Roberts JM, et al. (1994a). p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev 8:9-22.
-
(1994)
Genes Dev
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.Y.2
Solomon, M.J.3
Sherr, C.J.4
Massagué, J.5
Roberts, J.M.6
-
94
-
-
0028176483
-
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, et al. (1994b). Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
-
95
-
-
0029071257
-
Ultraviolet light induces expression of p53 and p21 in human skin: Effect of sunscreen and constitutive p21 expression in skin appendages
-
Ponten F, Berne B, Ren ZP, Nister M, Ponten J (1995). Ultraviolet light induces expression of p53 and p21 in human skin: effect of sunscreen and constitutive p21 expression in skin appendages. J Invest Dermatol 105:402-406.
-
(1995)
J Invest Dermatol
, vol.105
, pp. 402-406
-
-
Ponten, F.1
Berne, B.2
Ren, Z.P.3
Nister, M.4
Ponten, J.5
-
96
-
-
0032510269
-
Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells
-
Poon RY, Hunter T (1998). Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells. Oncogene 16:1333-1343.
-
(1998)
Oncogene
, vol.16
, pp. 1333-1343
-
-
Poon, R.Y.1
Hunter, T.2
-
97
-
-
0031022420
-
Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation
-
Prowse DM, Bolgan L, Molnar A, Dotto GP (1997). Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation. J Biol Chem 272:1308-1314.
-
(1997)
J Biol Chem
, vol.272
, pp. 1308-1314
-
-
Prowse, D.M.1
Bolgan, L.2
Molnar, A.3
Dotto, G.P.4
-
98
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, et al. (2001). Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 20:3427-3436.
-
(2001)
EMBO J
, vol.20
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
Nicolas, M.4
Mammucari, C.5
Oh, H.6
-
99
-
-
0019124443
-
Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes
-
Rheinwald JG, Beckett MA (1980). Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell 22:629-632.
-
(1980)
Cell
, vol.22
, pp. 629-632
-
-
Rheinwald, J.G.1
Beckett, M.A.2
-
100
-
-
0034941567
-
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells
-
Rossig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S (2001). Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol 21:5644-5657.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
101
-
-
0037155824
-
Glycogen synthase kinase-3 couples Akt-dependent signaling to the regulation of p21(Cip1) degradation
-
Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeler S (2002). Glycogen synthase kinase-3 couples Akt-dependent signaling to the regulation of p21(Cip1) degradation. J Biol Chem 277:9684-9689.
-
(2002)
J Biol Chem
, vol.277
, pp. 9684-9689
-
-
Rossig, L.1
Badorff, C.2
Holzmann, Y.3
Zeiher, A.M.4
Dimmeler, S.5
-
102
-
-
0033615003
-
Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway
-
Rousseau D, Cannella D, Boulaire J, Fitzgerald P, Fotedar A, Fotedar R (1999). Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway. Oncogene 18:4313-4325.
-
(1999)
Oncogene
, vol.18
, pp. 4313-4325
-
-
Rousseau, D.1
Cannella, D.2
Boulaire, J.3
Fitzgerald, P.4
Fotedar, A.5
Fotedar, R.6
-
103
-
-
0028820298
-
A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress
-
Russo T, Zambrano N, Esposito F, Ammendola R, Cimino F, Fiscella M, et al. (1995). A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress. J Biol Chem 270:29386-29391.
-
(1995)
J Biol Chem
, vol.270
, pp. 29386-29391
-
-
Russo, T.1
Zambrano, N.2
Esposito, F.3
Ammendola, R.4
Cimino, F.5
Fiscella, M.6
-
104
-
-
0032477945
-
Alterations in NFkappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB
-
Seitz CS, Lin Q, Deng H, Khavari PA (1998). Alterations in NFkappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proc Natl Acad Sci USA 95:2307-2312.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2307-2312
-
-
Seitz, C.S.1
Lin, Q.2
Deng, H.3
Khavari, P.A.4
-
105
-
-
0033624673
-
Nuclear factor kappaB subunits induce epithelial cell growth arrest
-
Seitz CS, Deng H, Hinata K, Lin Q, Khavari PA (2000). Nuclear factor kappaB subunits induce epithelial cell growth arrest. Cancer Res 60:4085-4092.
-
(2000)
Cancer Res
, vol.60
, pp. 4085-4092
-
-
Seitz, C.S.1
Deng, H.2
Hinata, K.3
Lin, Q.4
Khavari, P.A.5
-
106
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
Serrano M, Lee H, Chin L, Cordon-Cardo C, Beach D, DePinho RA (1996). Role of the INK4a locus in tumor suppression and cell mortality. Cell 85:27-37.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
DePinho, R.A.6
-
108
-
-
0033623850
-
Proteasomal turnover of p21cip1 does not require p21cipI ubiquitination
-
Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM, Clurman BE (2000). Proteasomal turnover of p21cip1 does not require p21cipI ubiquitination. Mol Cell 5:403-410.
-
(2000)
Mol Cell
, vol.5
, pp. 403-410
-
-
Sheaff, R.J.1
Singer, J.D.2
Swanger, J.3
Smitherman, M.4
Roberts, J.M.5
Clurman, B.E.6
-
109
-
-
0028988585
-
Inhibitors of mammalian G1 cyclindependent kinases
-
Sherr CJ, Roberts JM (1995). Inhibitors of mammalian G1 cyclindependent kinases. Genes Dev 9:1149-1163.
-
(1995)
Genes Dev
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
110
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr CJ, Roberts JM (1999). CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13:1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
111
-
-
0029957019
-
A non-enzymatic p21 protein inhibitor of stress-activated protein kinases
-
Shim J, Lee H, Park J, Kim H, Choi EJ (1996). A non-enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature 381:804-806.
-
(1996)
Nature
, vol.381
, pp. 804-806
-
-
Shim, J.1
Lee, H.2
Park, J.3
Kim, H.4
Choi, E.J.5
-
112
-
-
0027940495
-
Absence of WAF1 mutations in a variety of human malignancies
-
Shiohara M, El Deiry WS, Wada M, Nakamaki T, Takeuchi S, Yang R, et al. (1994). Absence of WAF1 mutations in a variety of human malignancies. Blood 84:3781-3784.
-
(1994)
Blood
, vol.84
, pp. 3781-3784
-
-
Shiohara, M.1
El Deiry, W.S.2
Wada, M.3
Nakamaki, T.4
Takeuchi, S.5
Yang, R.6
-
113
-
-
0031754316
-
Molecular mechanisms for the senescent cell cycle arrest
-
Stein GH, Dulic V (1998). Molecular mechanisms for the senescent cell cycle arrest. J Invest Dermatol Symp Proc 3:14-18.
-
(1998)
J Invest Dermatol Symp Proc
, vol.3
, pp. 14-18
-
-
Stein, G.H.1
Dulic, V.2
-
114
-
-
0023875418
-
Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts
-
Strickland JE, Greenhalgh DA, Koceva-Chyla A, Hennings H, Restrepo C, Balaschak M, et al. (1988). Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts. Cancer Res 48:165-169.
-
(1988)
Cancer Res
, vol.48
, pp. 165-169
-
-
Strickland, J.E.1
Greenhalgh, D.A.2
Koceva-Chyla, A.3
Hennings, H.4
Restrepo, C.5
Balaschak, M.6
-
116
-
-
0033521925
-
Caspase 3 inactivation to suppress Fas-mediated apoptosis: Identification of binding domain with p21 and ILP and inactivation machinery by p21
-
Suzuki A, Tsutomi Y, Miura M, Akahane K (1999). Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene 18:1239-1244.
-
(1999)
Oncogene
, vol.18
, pp. 1239-1244
-
-
Suzuki, A.1
Tsutomi, Y.2
Miura, M.3
Akahane, K.4
-
117
-
-
0033894919
-
Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A
-
Suzuki A, Kawano H, Hayashida M, Hayasaki Y, Tsutomi Y, Akahane K (2000). Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A. Cell Death Differ 7:721-728.
-
(2000)
Cell Death Differ
, vol.7
, pp. 721-728
-
-
Suzuki, A.1
Kawano, H.2
Hayashida, M.3
Hayasaki, Y.4
Tsutomi, Y.5
Akahane, K.6
-
118
-
-
0028945659
-
Modulation of epidermal differentiation by epiligrin and integrin alpha 3 beta 1
-
Symington BE, Carter WG (1995). Modulation of epidermal differentiation by epiligrin and integrin alpha 3 beta 1. J Cell Sci 108(Pt 2):831-838.
-
(1995)
J Cell Sci
, vol.108
, Issue.PART 2
, pp. 831-838
-
-
Symington, B.E.1
Carter, W.G.2
-
119
-
-
0031596501
-
WAF1 by phorbol ester and calcium in human keratinocytes through a protein kinase C-dependent pathway
-
WAF1 by phorbol ester and calcium in human keratinocytes through a protein kinase C-dependent pathway. Am J Pathol 153:39-45.
-
(1998)
Am J Pathol
, vol.153
, pp. 39-45
-
-
Todd, C.1
Reynolds, N.J.2
-
120
-
-
0033529790
-
p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential
-
Topley GI, Okuyama R, Gonzales JG, Conti C, Dotto GP (1999). p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential. Proc Natl Acad Sci USA 96:9089-9094.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9089-9094
-
-
Topley, G.I.1
Okuyama, R.2
Gonzales, J.G.3
Conti, C.4
Dotto, G.P.5
-
121
-
-
0028363519
-
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
-
Toyoshima H, Hunter T (1994). p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
122
-
-
0029815820
-
Differentiation-associated overexpression of the cyclin-dependent kinase inhibitor p21waf-1 in human cutaneous squamous cell carcinoma
-
Tron VA, Tang L, Yong WP, Trotter MJ (1996). Differentiation-associated overexpression of the cyclin-dependent kinase inhibitor p21waf-1 in human cutaneous squamous cell carcinoma. Am J Pathol 149:1139-1146.
-
(1996)
Am J Pathol
, vol.149
, pp. 1139-1146
-
-
Tron, V.A.1
Tang, L.2
Yong, W.P.3
Trotter, M.J.4
-
123
-
-
0032167646
-
Expression of p21 (Waf1/Cip1) in head and neck cancer in relation to proliferation, differentiation, p53 status and D1 expression
-
van Oijen MG, Tilanus MG, Medema RH, Slootweg PJ (1998). Expression of p21 (Waf1/Cip1) in head and neck cancer in relation to proliferation, differentiation, p53 status and D1 expression. J Oral Pathol Med 27:367-375.
-
(1998)
J Oral Pathol Med
, vol.27
, pp. 367-375
-
-
Van Oijen, M.G.1
Tilanus, M.G.2
Medema, R.H.3
Slootweg, P.J.4
-
124
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga S, Hannon GJ, Beach D, Stillman B (1994). The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578.
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
125
-
-
0034804926
-
Protein kinase C is involved in the regulation of hairless mRNA expression during mouse keratinocyte differentiation
-
Wan X, Kong J, Li YC (2001). Protein kinase C is involved in the regulation of hairless mRNA expression during mouse keratinocyte differentiation. Biochem Biophys Res Commun 294:99-105.
-
(2001)
Biochem Biophys Res Commun
, vol.294
, pp. 99-105
-
-
Wan, X.1
Kong, J.2
Li, Y.C.3
-
126
-
-
0031474756
-
Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice
-
Wang YA, Elson A, Leder P (1997). Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice. Proc Natl Acad Sci USA 94:14590-14595.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14590-14595
-
-
Wang, Y.A.1
Elson, A.2
Leder, P.3
-
128
-
-
0029057464
-
p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein
-
Weinberg WC, Azzoli CG, Chapman K, Levine AJ, Yuspa SH (1995). p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene 10:2271-2279.
-
(1995)
Oncogene
, vol.10
, pp. 2271-2279
-
-
Weinberg, W.C.1
Azzoli, C.G.2
Chapman, K.3
Levine, A.J.4
Yuspa, S.H.5
-
129
-
-
0030611856
-
Loss of p21CIP1/WAF1 does not recapitulate accelerated malignant conversion caused by p53 loss in experimental skin carcinogenesis
-
Weinberg WC, Montano NE, Deng C (1997). Loss of p21CIP1/WAF1 does not recapitulate accelerated malignant conversion caused by p53 loss in experimental skin carcinogenesis. Oncogene 15:685-690.
-
(1997)
Oncogene
, vol.15
, pp. 685-690
-
-
Weinberg, W.C.1
Montano, N.E.2
Deng, C.3
-
131
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D (1993a). p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
132
-
-
0027301324
-
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
-
Xiong Y, Zhang H, Beach D (1993b). Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev 7:1572-1583.
-
(1993)
Genes Dev
, vol.7
, pp. 1572-1583
-
-
Xiong, Y.1
Zhang, H.2
Beach, D.3
-
133
-
-
0035863515
-
Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal
-
Yang WC, Mathew J, Velcich A, Edelmann W, Kucherlapati R, Lipkin M, et al. (2001). Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. Cancer Res 61:565-569.
-
(2001)
Cancer Res
, vol.61
, pp. 565-569
-
-
Yang, W.C.1
Mathew, J.2
Velcich, A.3
Edelmann, W.4
Kucherlapati, R.5
Lipkin, M.6
-
134
-
-
0033122885
-
Transcriptional activation of the cyclindependent kinase inhibitor p21 by PML/RARalpha
-
Yang WL, Zeng YX, El Deiry WS, Nason-Burchenal K, Dmitrovsky E, Chin KV (1999). Transcriptional activation of the cyclindependent kinase inhibitor p21 by PML/RARalpha. Mol Cell Biol Res Commun 1:125-131.
-
(1999)
Mol Cell Biol Res Commun
, vol.1
, pp. 125-131
-
-
Yang, W.L.1
Zeng, Y.X.2
El Deiry, W.S.3
Nason-Burchenal, K.4
Dmitrovsky, E.5
Chin, K.V.6
-
135
-
-
0032078740
-
WAF1/CIP1 is unrelated to p53 tumour suppressor gene status in oral squamous cell carcinomas
-
WAF1/CIP1 is unrelated to p53 tumour suppressor gene status in oral squamous cell carcinomas. Oral Oncol 34:198-203.
-
(1998)
Oral Oncol
, vol.34
, pp. 198-203
-
-
Yook, J.I.1
Kim, J.2
-
136
-
-
0028351556
-
The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis - Thirty-third G.H.A. Clowes Memorial Award Lecture
-
Yuspa SH (1994). The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis - thirty-third G.H.A. Clowes Memorial Award Lecture. Cancer Res 54:1178-1189.
-
(1994)
Cancer Res
, vol.54
, pp. 1178-1189
-
-
Yuspa, S.H.1
-
137
-
-
0024454035
-
Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro
-
Yuspa SH, Kilkenny AE, Steinert PM, Roop DR (1989). Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol 109:1207-1217.
-
(1989)
J Cell Biol
, vol.109
, pp. 1207-1217
-
-
Yuspa, S.H.1
Kilkenny, A.E.2
Steinert, P.M.3
Roop, D.R.4
-
138
-
-
0029125444
-
The tumor suppression function of p21Waf is contained in its N-terminal half ('half-WAF')
-
Zakut R, Givol D (1995). The tumor suppression function of p21Waf is contained in its N-terminal half ('half-WAF'). Oncogene 11:393-395.
-
(1995)
Oncogene
, vol.11
, pp. 393-395
-
-
Zakut, R.1
Givol, D.2
-
139
-
-
0029670422
-
WAF1/CIP1 expression by p53-independent pathways
-
WAF1/CIP1 expression by p53-independent pathways. Oncogene 12:1557-1564.
-
(1996)
Oncogene
, vol.12
, pp. 1557-1564
-
-
Zeng, Y.X.1
El Deiry, W.S.2
-
140
-
-
0033556237
-
p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step
-
Zhang P, Wong C, Liu D, Finegold M, Harper JW, Elledge SJ (1999). p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev 13:213-224.
-
(1999)
Genes Dev
, vol.13
, pp. 213-224
-
-
Zhang, P.1
Wong, C.2
Liu, D.3
Finegold, M.4
Harper, J.W.5
Elledge, S.J.6
-
141
-
-
0033521889
-
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
-
Zhang Y, Fujita N, Tsuruo T (1999). Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis. Oncogene 18:1131-1138.
-
(1999)
Oncogene
, vol.18
, pp. 1131-1138
-
-
Zhang, Y.1
Fujita, N.2
Tsuruo, T.3
-
142
-
-
0034745353
-
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylafion in HER-2/neu-overexpressing cells
-
Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC (2001). Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylafion in HER-2/neu-overexpressing cells. Nat Cell Biol 3:245-252.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 245-252
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Spohn, B.4
Lee, M.H.5
Hung, M.C.6
-
143
-
-
0030460336
-
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes
-
Zhu AJ, Watt FM (1996). Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J Cell Sci 109(Pt 13):3013-3023.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 13
, pp. 3013-3023
-
-
Zhu, A.J.1
Watt, F.M.2
|