Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

Current Biology

Volumn 6, Issue 2, 1996, Pages 189-199

  Li, Rong ^a   Hannon, Gregory J ^b   Beach, David ^b   Stillman, Bruce ^a  

^a Simons Center for Quantitative Biology   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DETERGENT;

ARTICLE; BIOSYNTHESIS; CELL CYCLE; CELL LINE; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; HUMAN; METABOLISM; PHYSIOLOGY;

CELL CYCLE; CELL LINE; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DETERGENTS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; HUMANS; PROLIFERATING CELL NUCLEAR ANTIGEN;

EID: 0030088038     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00452-9     Document Type: Article

References (17)

1. Hartwell LH, Kastan MB: Cell cycle control and cancer. Science 1994, 266:1821-1828.
2. Nigg EA: Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays 1995, 17:471.
3. Nurse P: Ordering S. phase and M phase in the cell cycle. Cell 1994, 79:547-550.
4. Sherr CJ, M RJ: Inhibitors of mammalian G, cyclin-dependent kinases. Genes Dev 1995, 9:1149-1163.
5. Peter M, Herskowitz I: Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 1994, 79:181-184.
6. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al.: WAF1, a potential mediator of p53 tumor suppression. Cell 1993, 75:817-825.
7. Gu Y, Turck CW, Morgan DO: Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit Nature 1993, 366:707-710.
8. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ: The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
9. 1 arrest Cell 1994, 76:1013-1023.
10. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D: p21 is a universal Inhibitor of cyclin kinases. Nature 1993, 366:701-704.
11. Li Y, Jenkins CW, Nichols MA, Xiong Y: Cell-cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene 1994, 9:2261-2268.
12. Noda A, Ning Y, Venable SF, Pereira-Smith OM, Smith JR: Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 1994, 211:90-98.
13. Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, et at.: Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 1995, 267:1018-1021.
14. cip1 in muscle and other terminally differentiating cells. Science 1995, 267:1024-1027.
15. Michieli P, Chedid M, Lin D, Pierce JH, Mercer WE, Givol D: Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res 1994, 54:3391-3395.
16. Johnson M, Dimitrov D, Vojta PJ, Barrett JC, Noda A, Pereira-Smith OM, ef al.: Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/WAF1/p21 RNA in human cells. Mol Carcinog 1994, 11:59-64.
17. Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, et al.: p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 1995, 9:935-944.