-
11
-
-
0023631608
-
-
49:415- 475, 1987
-
Sinn E, Muller W, Pattengale P, Tapler I, Wallace R, Leder , P: Co-expression of mouse v-Ha-ras and MMTV/c-myc genes in transgenic mice; synergistic action of oncogenes in vivo. Cell 49:415- 475, 1987
-
Muller W, Pattengale P, Tapler I, Wallace R, Leder , P: Co-expression of Mouse V-Ha-ras and MMTV/c-myc Genes in Transgenic Mice; Synergistic Action of Oncogenes in Vivo. Cell
-
-
Sinn, E.1
-
14
-
-
0020596528
-
-
304:67-69, 1983
-
Hennings H, Shores R, Wenk ML, Spangler LF, Tarone R, Yuspa S, H: Malignant conversion of mouse skin tumors is increased by tumor initiators and unaffected by tumor promoters. Nature 304:67-69, 1983
-
Shores R, Wenk ML, Spangler LF, Tarone R, Yuspa S, H: Malignant Conversion of Mouse Skin Tumors Is Increased by Tumor Initiators and Unaffected by Tumor Promoters. Nature
-
-
Hennings, H.1
-
19
-
-
0027516110
-
-
7:99-110, 1993
-
Greenhalgh DA, Rothnagel JA, Quintanilla Ml, Orengo C, Gagne TA, Bundman DS, Longley MA, Roop D, R: Induction of epidermal hyperplasia, hyperkeratosis and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. AW Carcinog 7:99-110, 1993
-
Rothnagel JA, Quintanilla Ml, Orengo C, Gagne TA, Bundman DS, Longley MA, Roop D, R: Induction of Epidermal Hyperplasia, Hyperkeratosis and Papillomas in Transgenic Mice by A Targeted V-Ha-ras Oncogene. AW Carcinog
-
-
Greenhalgh, D.A.1
-
20
-
-
0027280087
-
-
0,108:2145-2157,1993
-
Greenhalgh DA, Rothnagel JA, Wang X-J, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop D, R: Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggests a role for fos in epidermal differentiation and neoplasia. 0,108:2145-2157,1993
-
Rothnagel JA, Wang X-J, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop D, R: Hyperplasia, Hyperkeratosis and Benign Tumor Production in Transgenic Mice by A Targeted V-fos Oncogene Suggests A Role for Fos in Epidermal Differentiation and Neoplasia.
-
-
Greenhalgh, D.A.1
-
21
-
-
0027767476
-
-
1993
-
Dominey AM, Wang X-J, King LE, Jr. Nanney LE, Gagne TA, Sellheyer K, Bundman DS, Longley MA, Rothnagel JA, Greenhalgh DA, Roop D, R: Targeted overexpression of transforming growth factor-a in the epidermis of transgenic mice eb'cits hyperplasia, hyperkeratosis and spontaneous squamous papillomas. Cell Grou-th and Dif4:1071-1082, 1993
-
Wang X-J, King LE, Jr. Nanney LE, Gagne TA, Sellheyer K, Bundman DS, Longley MA, Rothnagel JA, Greenhalgh DA, Roop D, R: Targeted Overexpression of Transforming Growth Factor-a in the Epidermis of Transgenic Mice Eb'cits Hyperplasia, Hyperkeratosis and Spontaneous Squamous Papillomas. Cell Grou-th and Dif4:1071-1082
-
-
Dominey, A.M.1
-
23
-
-
0027359975
-
-
53:5071-5075, 1993
-
Greenhalgh DA, Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop D, R: Cooperation between v-fos and v-rasH" induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Re! 53:5071-5075, 1993
-
Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop D, R: Cooperation between V-fos and V-rasH" Induces Autonomous Papillomas in Transgenic Epidermis but Not Malignant Conversion. Cancer Re!
-
-
Greenhalgh, D.A.1
-
24
-
-
0028332305
-
-
10:15-22, 1994
-
Wang X-J, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop D, R: Epidermal expression of TGFot in transgenic mice elicits spontaneous and TPA induced papillomas via a mechanism independent of mi"4 activation or overexpressïon. Mol Carcinog 10:15-22, 1994
-
Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop D, R: Epidermal Expression of TGFot in Transgenic Mice Elicits Spontaneous and TPA Induced Papillomas Via A Mechanism Independent of Mi"4 Activation or Overexpressïon. Mol Carcinog
-
-
Wang, X.-J.1
-
25
-
-
0028985020
-
-
10:219-289, 1995
-
Wang XJ, Greenhalgh DA, Bickenbach JR, Roop D, R: TGFa and v-fos cooperation in transgenic mouse epidermis induces aberant differentiation and stable autonomous papillomas. Oncogene 10:219-289, 1995
-
Greenhalgh DA, Bickenbach JR, Roop D, R: TGFa and V-fos Cooperation in Transgenic Mouse Epidermis Induces Aberant Differentiation and Stable Autonomous Papillomas. Oncogene
-
-
Wang, X.J.1
-
27
-
-
0025041030
-
-
62:697708, 1990
-
Bailleul B. Surani MA, White S, Barton SC, Brown K, Blessing M, Jorcano J, Balmain , A: Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. Cell 62:697708, 1990
-
Surani MA, White S, Barton SC, Brown K, Blessing M, Jorcano J, Balmain , A: Skin Hyperkeratosis and Papilloma Formation in Transgenic Mice Expressing A Ras Oncogene from A Suprabasal Keratin Promoter. Cell
-
-
Bailleul, B.1
-
31
-
-
0027951484
-
-
1994
-
Chung SY, Cheng CK, Rothnagel JA, Yu SH, Nakazawa H, Mehrel T, Hohl D, Rosenthal DS, Steinen PM, Yuspa SH, Roop D, R: Expression of human keratin gene (Kl) in transgenic mice is tissue and developmental-specific but altered with respect to differentiation state. Mol Cell Di/2:61-81, 1994
-
Cheng CK, Rothnagel JA, Yu SH, Nakazawa H, Mehrel T, Hohl D, Rosenthal DS, Steinen PM, Yuspa SH, Roop D, R: Expression of Human Keratin Gene (Kl) in Transgenic Mice Is Tissue and Developmental-specific but Altered with Respect to Differentiation State. Mol Cell Di/2:61-81
-
-
Chung, S.Y.1
-
32
-
-
0026110473
-
-
2:107-113, 1991
-
Rosenthal DS, Steinen PM, Chung C, Huff CA, Yuspa SH, Roop D, R: A human epidermal differentiation specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Grouth ami Dig 2:107-113, 1991
-
Steinen PM, Chung C, Huff CA, Yuspa SH, Roop D, R: A Human Epidermal Differentiation Specific Keratin Gene Is Regulated by Calcium but Not Negative Modulators of Differentiation in Transgenic Mouse Keratinocytes. Cell Grouth Ami Dig
-
-
Rosenthal, D.S.1
-
37
-
-
0027153103
-
-
73:611-620, 1993
-
Buday L, Downward , J: Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell 73:611-620, 1993
-
Downward , J: Epidermal Growth Factor Regulates P21ras Through the Formation of A Complex of Receptor, Grb2 Adapter Protein, and Sos Nucleotide Exchange Factor. Cell
-
-
Buday, L.1
-
38
-
-
33745566553
-
-
132:55005512, 1993
-
Suen KL, Bustelo XR, Pawson T, Barbacid , M: Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors. Mol Cell Biol 132:55005512, 1993
-
Bustelo XR, Pawson T, Barbacid , M: Molecular Cloning of the Mouse Grb2 Gene: Differential Interaction of the Grb2 Adaptor Protein with Epidermal Growth Factor and Nerve Growth Factor Receptors. Mol Cell Biol
-
-
Suen, K.L.1
-
39
-
-
0027215820
-
-
260:315-319, 1993
-
Lang-Caner CA, Plenman CM, Gardner AM, Blumer KJ, Johnson G, L: A divergence in the MAP kinase regulatory network denned by MEK Kinase and RAF. Science 260:315-319, 1993
-
Plenman CM, Gardner AM, Blumer KJ, Johnson G, L: A Divergence in the MAP Kinase Regulatory Network Denned by MEK Kinase and RAF. Science
-
-
Lang-Caner, C.A.1
-
42
-
-
0027229556
-
-
363:88-92, 1993
-
Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi , D: Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 363:88-92, 1993
-
Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi , D: Grb2 Mediates the EGF-dependent Activation of Guanine Nucleotide Exchange on Ras. Nature
-
-
Gale, N.W.1
-
44
-
-
0025772556
-
-
4:196-202, 1991 .
-
Pierceall WE, Goldberg LH, Tainsky MA, Mukhopadhyay T, Ananthaswamy , H: H-Ras gene mutations and amplification in human nonmelanoma skin cancers. Mol Carcinog 4:196-202, 1991 .
-
Goldberg LH, Tainsky MA, Mukhopadhyay T, Ananthaswamy , H: H-Ras Gene Mutations and Amplification in Human Nonmelanoma Skin Cancers. Mol Carcinog
-
-
Pierceall, W.E.1
-
45
-
-
0021928956
-
-
314:459-462, 1985
-
Yuspa SH, Kilkenny AE, Stanley J, Lichti , U: Keratinocytes blocked in phorbol ester responsive early stage of terminal differentiation by Sarcoma viruses. Nature 314:459-462, 1985
-
Kilkenny AE, Stanley J, Lichti , U: Keratinocytes Blocked in Phorbol Ester Responsive Early Stage of Terminal Differentiation by Sarcoma Viruses. Nature
-
-
Yuspa, S.H.1
-
46
-
-
0022527161
-
-
322:78-80, 1986
-
Quintanilla M, Brown K, Ramsden M, Balmain , A: Carcinogen specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 322:78-80, 1986
-
Brown K, Ramsden M, Balmain , A: Carcinogen Specific Mutation and Amplification of Ha-ras during Mouse Skin Carcinogenesis. Nature
-
-
Quintanilla, M.1
-
48
-
-
0026723607
-
-
89:6398-6402, 1992
-
Nelson MA, Futscher BW, Kinsella T, Wymer J, Bowden G, T: Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors. Proc Nail Acad Sci USA 89:6398-6402, 1992
-
Futscher BW, Kinsella T, Wymer J, Bowden G, T: Detection of Mutant Ha-ras Genes in Chemically Initiated Mouse Skin Epidermis before the Development of Benign Tumors. Proc Nail Acad Sci USA
-
-
Ma, N.1
-
49
-
-
0022977903
-
-
323:822-824, 1986
-
Roop DR, Lowy DR. Tamborin PE, Stickland JE, Harper JR, Balaschak M, Spangler EG, Yuspa S, H: An activated Harvey ras oncogene produces benign tumors on mouse epidermal tissue. Nature 323:822-824, 1986
-
Lowy DR. Tamborin PE, Stickland JE, Harper JR, Balaschak M, Spangler EG, Yuspa S, H: An Activated Harvey Ras Oncogene Produces Benign Tumors on Mouse Epidermal Tissue. Nature
-
-
Roop, D.R.1
-
50
-
-
0024334332
-
-
43:915-921. 1989
-
Furstenberger G, Rogers M, Schnapke R, Bauer G, Hofler P, Marks , F: Simulatory role of transforming growth factors in multistage skin carcinogens: possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin. IntJ Cancer 43:915-921. 1989
-
Rogers M, Schnapke R, Bauer G, Hofler P, Marks , F: Simulatory Role of Transforming Growth Factors in Multistage Skin Carcinogens: Possible Explanation for the Tumor-inducing Effect of Wounding in Initiated NMRI Mouse Skin. IntJ Cancer
-
-
Furstenberger, G.1
-
51
-
-
0022458856
-
-
46:447-456, 1986
-
Brown K, Quintanilla M, Ramsden M, Kerr IB, Young S, Balmain A: v-ras genes from Harvey and BALD murine sarcoma viruses can act as initiators of two stage mouse skin carcinogenesis. Cell 46:447-456, 1986
-
Quintanilla M, Ramsden M, Kerr IB, Young S, Balmain A: V-ras Genes from Harvey and BALD Murine Sarcoma Viruses Can Act As Initiators of Two Stage Mouse Skin Carcinogenesis. Cell
-
-
Brown, K.1
-
52
-
-
0026349058
-
-
6:2363-2369, 1990
-
Bums PA, Kemp CJ, Cannon JV, Lane DP, Bremner R, Balniain , A: Loss of heterozygosity and mutational alterations of the p53 gene in skin tumors of interspecific hybrid mice. Ottcogent 6:2363-2369, 1990
-
Kemp CJ, Cannon JV, Lane DP, Bremner R, Balniain , A: Loss of Heterozygosity and Mutational Alterations of the P53 Gene in Skin Tumors of Interspecific Hybrid Mice. Ottcogent
-
-
Bums, P.A.1
-
53
-
-
0026346885
-
-
51:6615-6621, 1991
-
Ruggeri B, Caamano J, Goodrow T, DiRado M, Bianchi A, Trono D, Conti CJ, Klein-Santo AJ, P: Alterations of the p53 tumor suppressor gene during mouse skin tumor progression. Cancer Res 51:6615-6621, 1991
-
Caamano J, Goodrow T, DiRado M, Bianchi A, Trono D, Conti CJ, Klein-Santo AJ, P: Alterations of the P53 Tumor Suppressor Gene during Mouse Skin Tumor Progression. Cancer Res
-
-
Ruggeri, B.1
-
54
-
-
0024329752
-
-
2:199-207, 1989
-
Greenhalgh DA, Welty DJ, Stickland JE, Yuspa S, H: Spontaneous Ha-ras gene activation in cultured primary murine kerarinocytes: consequences of Ha-ras gene activation in malignant conversion and malignant progression. Alol Carcinog 2:199-207, 1989
-
Welty DJ, Stickland JE, Yuspa S, H: Spontaneous Ha-ras Gene Activation in Cultured Primary Murine Kerarinocytes: Consequences of Ha-ras Gene Activation in Malignant Conversion and Malignant Progression. Alol Carcinog
-
-
Greenhalgh, D.A.1
-
57
-
-
33745557580
-
-
1988, pp 307-325
-
Curran , T: The fos oncogene. In: Reddy EP, Skalka AM, Curran T (eds.). Tlie Ontogent Handbook. Elsevier Science Press, Amsterdam, 1988, pp 307-325
-
The Fos Oncogene. In: Reddy EP, Skalka AM, Curran T (Eds.). Tlie Ontogent Handbook. Elsevier Science Press, Amsterdam
-
-
Curran, T.1
-
60
-
-
0027159087
-
-
363:166-169, 1993
-
Smeyne RJ, Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T, Morgan J, I: Continuous c-fos expression precedes programmed cell death in vivo. Nature 363:166-169, 1993
-
Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T, Morgan J, I: Continuous C-fos Expression Precedes Programmed Cell Death in Vivo. Nature
-
-
Smeyne, R.J.1
-
63
-
-
0025326219
-
-
94:418-442, 1990
-
Basset-Seguin N, Escot C, Blanchard JM, Kerai C, Verrier B, Mïon H, Guillou J, J: High levels of c-fos proto-oncogene expression in normal human adult skin. J Invest Dermatol 94:418-442, 1990
-
Escot C, Blanchard JM, Kerai C, Verrier B, Mïon H, Guillou J, J: High Levels of C-fos Proto-oncogene Expression in Normal Human Adult Skin. J Invest Dermatol
-
-
Basset-Seguin, N.1
-
64
-
-
0026029316
-
-
111:253-258, 1992
-
Fisher C, Byers MR, ladarola MJ, Powers E, A: Patterns of epithelial expression of fos protein suggests an important role in the transition from viable to cornified cells during keratinization. Development 111:253-258, 1992
-
Byers MR, Ladarola MJ, Powers E, A: Patterns of Epithelial Expression of Fos Protein Suggests An Important Role in the Transition from Viable to Cornified Cells during Keratinization. Development
-
-
Fisher, C.1
-
65
-
-
0026585377
-
-
8:13-23, 1992
-
Smeyne RJ, Schilling K, Roberton L, Luk D, Oberdick J, Curran T, Morgan JL: fos-LacZ transgenic mice: mapping sites of gene introduction in the central nervous system. Neuron 8:13-23, 1992
-
Schilling K, Roberton L, Luk D, Oberdick J, Curran T, Morgan JL: Fos-LacZ Transgenic Mice: Mapping Sites of Gene Introduction in the Central Nervous System. Neuron
-
-
Smeyne, R.J.1
-
68
-
-
0023892768
-
-
9:831835, 1988
-
Rose-John S, Furstenberger G, Krieg P, Besemfelder E, Rincke G, Marks , F: Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo. Carcinogenesis 9:831835, 1988
-
Furstenberger G, Krieg P, Besemfelder E, Rincke G, Marks , F: Differential Effects of Phorbol Esters on C-fos and C-myc and Ornithine Decarboxylase Gene Expression in Mouse Skin in Vivo. Carcinogenesis
-
-
Rose-John, S.1
-
69
-
-
0023081620
-
-
7:523-527, 1987
-
Stacy D\V, Watson T, Kung H, Curran , T: Microinjection of transforming ras proteins induces c-fos expression. Mol Cell Biol 7:523-527, 1987
-
Watson T, Kung H, Curran , T: Microinjection of Transforming Ras Proteins Induces C-fos Expression. Mol Cell Biol
-
-
Stacy, D.V.1
-
71
-
-
0025141320
-
-
87:643-647, 1990
-
Greenhalgh DA, Welty DJ, Player A, Yuspa S, H: Two oncogenes v-fos and v-ras cooperate to convert noral keratinocytes to squamous cell carcinoma. Proc Natl Acad Sci USA 87:643-647, 1990
-
Welty DJ, Player A, Yuspa S, H: Two Oncogenes V-fos and V-ras Cooperate to Convert Noral Keratinocytes to Squamous Cell Carcinoma. Proc Natl Acad Sci USA
-
-
Greenhalgh, D.A.1
-
73
-
-
0024271965
-
-
1 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia. Mol Caninog 1:96-108, 1988
-
Mischt R, Roop DR, Mehrel T, Yuspa SH, Rentrop M, Winter H, Schweizer , J: Aberant expression during two stage mouse skin carcinogenesis of a type 1 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia. Mol Caninog 1:96-108, 1988
-
Roop DR, Mehrel T, Yuspa SH, Rentrop M, Winter H, Schweizer , J: Aberant Expression during Two Stage Mouse Skin Carcinogenesis of A Type
-
-
Mischt, R.1
-
74
-
-
0023898669
-
-
48:3245-3252, 1988
-
Roop DR, Krieg TM, Mehrel T, Cheng CK, Yuspa S, H: Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res 48:3245-3252, 1988
-
Krieg TM, Mehrel T, Cheng CK, Yuspa S, H: Transcriptional Control of High Molecular Weight Keratin Gene Expression in Multistage Mouse Skin Carcinogenesis. Cancer Res
-
-
Roop, D.R.1
-
80
-
-
0024554077
-
-
243:811-814, 1989
-
Elder JT, Fisher GJ, Lindquist PB, Bennelt GL, Pittelkow MR, Coffey RJ, EIHngsworth L, Derynck R, Voorhees J, J: Overexpression of transforming growth factor alpha in psoriatic epidermis. Science 243:811-814, 1989
-
Fisher GJ, Lindquist PB, Bennelt GL, Pittelkow MR, Coffey RJ, EIHngsworth L, Derynck R, Voorhees J, J: Overexpression of Transforming Growth Factor Alpha in Psoriatic Epidermis. Science
-
-
Elder, J.T.1
-
86
-
-
85142972813
-
-
83:385-393, 1984
-
Nanny LB, Magid M, Stoscheck CM, King LE, Jr: Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dennatol 83:385-393, 1984
-
Magid M, Stoscheck CM, King LE, Jr: Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages. J Invest Dennatol
-
-
Nanny, L.B.1
-
88
-
-
0023100052
-
-
47:707-712, 1987
-
Derynck H, Goeddel DV, Ullnich A, GuttermanJU, Williams RD, Bringman IS, Berger W, H: Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors. Cancer Res 47:707-712, 1987
-
Goeddel DV, Ullnich A, GuttermanJU, Williams RD, Bringman IS, Berger W, H: Synthesis of Messenger RNAs for Transforming Growth Factors Alpha and Beta and the Epidermal Growth Factor Receptor by Human Tumors. Cancer Res
-
-
Derynck, H.1
-
89
-
-
0024524971
-
-
264:5164-5171, 1989
-
Pittelkow M, Lindquist P, Abraham R, Graves-Deal R, Derynck R, Coffey , R: Induction of transforming growth factor-a expression in human keratinocytes by phorbol esters. J Dial Client 264:5164-5171, 1989
-
Lindquist P, Abraham R, Graves-Deal R, Derynck R, Coffey , R: Induction of Transforming Growth Factor-a Expression in Human Keratinocytes by Phorbol Esters. J Dial Client
-
-
Pittelkow, M.1
-
90
-
-
0024246652
-
-
1:7-12, 1988
-
Finzi E, Kilkenny A, Strickland JE, Derinck R, Aaronson S, Balaschak M, Bringman T, Yuspa S, H: TGF-a stimulates growth of skin papillomas by autocrine and paracrine mechanisms but does not cause neoplastic progression. Mot Carcinog 1:7-12, 1988
-
Kilkenny A, Strickland JE, Derinck R, Aaronson S, Balaschak M, Bringman T, Yuspa S, H: TGF-a Stimulates Growth of Skin Papillomas by Autocrine and Paracrine Mechanisms but Does Not Cause Neoplastic Progression. Mot Carcinog
-
-
Finzi, E.1
-
92
-
-
0025737543
-
-
1 and TGF alpha in primary keratinocytes and papillomas expressing v-Ha-ras. Mot Carcinog 4:210-219, 1991
-
Click AB, Sporn MB, Yuspa S, H: Altered regulation of TGF beta 1 and TGF alpha in primary keratinocytes and papillomas expressing v-Ha-ras. Mot Carcinog 4:210-219, 1991
-
Sporn MB, Yuspa S, H: Altered Regulation of TGF Beta
-
-
Click, A.B.1
-
93
-
-
0025341727
-
-
61:1137-1146, 1990
-
Jhappan C, Stable C, Harkins RN, Fausto N, Smith GH, Melrino G, T: TGF-a overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 61:1137-1146, 1990
-
Stable C, Harkins RN, Fausto N, Smith GH, Melrino G, T: TGF-a Overexpression in Transgenic Mice Induces Liver Neoplasia and Abnormal Development of the Mammary Gland and Pancreas. Cell
-
-
Jhappan, C.1
-
94
-
-
0025297086
-
-
61:1121-1135, 1990
-
Sandgren EP, Luetteke NC, Palmitcr RD, Brinster RL, Lee D, C: Overexpression of TGF-a in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia and carcinoma of the breast. Cell 61:1121-1135, 1990
-
Luetteke NC, Palmitcr RD, Brinster RL, Lee D, C: Overexpression of TGF-a in Transgenic Mice: Induction of Epithelial Hyperplasia, Pancreatic Metaplasia and Carcinoma of the Breast. Cell
-
-
Sandgren, E.P.1
-
95
-
-
0025372023
-
-
61:1147-1155, 1990
-
Matsui Y, Halter SA, Holt JT, Hogan BLM, Coffey RJ, Development of mammary hyperplasia and neoplasia in MMTV-TGFa transgenic mice. Cell 61:1147-1155, 1990
-
Halter SA, Holt JT, Hogan BLM, Coffey RJ, Development of Mammary Hyperplasia and Neoplasia in MMTV-TGFa Transgenic Mice. Cell
-
-
Matsui, Y.1
-
97
-
-
0021061917
-
-
100:506-512, 1983
-
Green MR, Basketter DA, Coudman JR, Ros D, A: Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth. Dev Biol 100:506-512, 1983
-
Basketter DA, Coudman JR, Ros D, A: Distribution and Number of Epidermal Growth Factor Receptors in Skin Is Related to Epithelial Cell Growth. Dev Biol
-
-
Green, M.R.1
-
98
-
-
0020316263
-
-
297:478-481, 1982
-
Chang EH, Furth M, Scolnick EM, Lowy D, R: Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature 297:478-481, 1982
-
Furth M, Scolnick EM, Lowy D, R: Tumorigenic Transformation of Mammalian Cells Induced by A Normal Human Gene Homologous to the Oncogene of Harvey Murine Sarcoma Virus. Nature
-
-
Chang, E.H.1
-
99
-
-
33745563635
-
-
257-304, 1988
-
Laçai JE, Tronick S, R: The ras oncogene. In: Reddy EP, Skalka AM, Curran T (eds.). The Oncogene Handbook. Elsevier, Amsterdam, p 257-304, 1988
-
Tronick S, R: the Ras Oncogene. In: Reddy EP, Skalka AM, Curran T (Eds.). the Oncogene Handbook. Elsevier, Amsterdam, P
-
-
Laçai, J.E.1
-
103
-
-
0024404938
-
-
86:8763-8769, 1986
-
Eliyahu D, Mechaloritz D, Eliyahu S, Pinhasi-Kimhi O, Oren , M: Wild-type p53 can inhibit oncogene mediated focus formation. Proc Nail Acai Sci USA 86:8763-8769, 1986
-
Mechaloritz D, Eliyahu S, Pinhasi-Kimhi O, Oren , M: Wild-type P53 Can Inhibit Oncogene Mediated Focus Formation. Proc Nail Acai Sci USA
-
-
Eliyahu, D.1
-
104
-
-
0027245446
-
-
53:1719-1723, 1993
-
Murakami H, Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson S, S: Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis-interaction of c-myc and transforming growth factor-alpha in hepatic oncogenesis. Cancer Res 53:1719-1723, 1993
-
Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson S, S: Transgenic Mouse Model for Synergistic Effects of Nuclear Oncogenes and Growth Factors in Tumorigenesis-interaction of C-myc and Transforming Growth Factor-alpha in Hepatic Oncogenesis. Cancer Res
-
-
Murakami, H.1
-
105
-
-
0027363255
-
-
123:877-893, 1993
-
Kim SH, Roth KA, Moser A, Grodon J, I: Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.J Cell Biol 123:877-893, 1993
-
Roth KA, Moser A, Grodon J, I: Transgenic Mouse Models That Explore the Multistep Hypothesis of Intestinal Neoplasia.J Cell Biol
-
-
Kim, S.H.1
-
106
-
-
0027406396
-
-
7:21-25, 1993
-
Brisette JL, Missero C, Yuspa SH, Dotto G, P: Different levels of v-Ha-ras p21 expression in primary keratinocytes transformed with Harvey Sarcoma virus correlate with benign versus malignant behavior. Mol Carcinog 7:21-25, 1993
-
Missero C, Yuspa SH, Dotto G, P: Different Levels of V-Ha-ras P21 Expression in Primary Keratinocytes Transformed with Harvey Sarcoma Virus Correlate with Benign Versus Malignant Behavior. Mol Carcinog
-
-
Brisette, J.L.1
-
107
-
-
0026561121
-
-
356:215-221, 1992
-
Donehower LA, Harvey M, Slagel BL, McArthur MJ, Montgomery CA, Jr, Butel JS, Bradley , A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356:215-221, 1992
-
Harvey M, Slagel BL, McArthur MJ, Montgomery CA, Jr, Butel JS, Bradley , A: Mice Deficient for P53 Are Developmentally Normal but Susceptible to Spontaneous Tumors. Nature
-
-
Donehower, L.A.1
-
108
-
-
0024287309
-
-
10T1/2 cells. Biocliem Biophys Res Commun 152:216-222, 1988
-
Cutry AF, Kinniburgh AJ, Twardzik DR, Wenner C, E: Transforming growth factor alpha (TGFa) induction of c-fos and c-myc expression in C3H 10T1/2 cells. Biocliem Biophys Res Commun 152:216-222, 1988
-
Kinniburgh AJ, Twardzik DR, Wenner C, E: Transforming Growth Factor Alpha (TGFa) Induction of C-fos and C-myc Expression in C3H
-
-
Cutry, A.F.1
-
110
-
-
0027931473
-
-
5:385-394, 1994
-
Jhappan C, Takayama H, Dickson RB, Melino , G: Transgenic mice provide genetic evidence that transforming growth fact a promotes skin tumorigen-esis via H-ras dependent and H-ras independent pathways. Cell Crou-th and Diff 5:385-394, 1994
-
Takayama H, Dickson RB, Melino , G: Transgenic Mice Provide Genetic Evidence That Transforming Growth Fact A Promotes Skin Tumorigen-esis Via H-ras Dependent and H-ras Independent Pathways. Cell Crou-th and Diff
-
-
Jhappan, C.1
-
111
-
-
0027493650
-
-
261:1722-1746, 1993
-
Shuai K, Stark GR, Kerr IM, Daraell Jr, J, E: A single phosphotyrosine residue of Stat p91 required for gene activation by interferon-y. Science 261:1722-1746, 1993
-
Stark GR, Kerr IM, Daraell Jr, J, E: A Single Phosphotyrosine Residue of Stat P91 Required for Gene Activation by Interferon-y. Science
-
-
Shuai, K.1
-
112
-
-
0028304809
-
-
1 is mediated by a composite AP-1 steroid hormone element. J Biol Client 209:7443-7449, 1996
-
Lu B, Rothnagel JA, Longley MA, Tsai SY, Roop D, R: Differentiation specific expression of human keratin 1 is mediated by a composite AP-1 steroid hormone element. J Biol Client 209:7443-7449, 1996
-
Rothnagel JA, Longley MA, Tsai SY, Roop D, R: Differentiation Specific Expression of Human Keratin
-
-
Lu, B.1
-
116
-
-
0025633582
-
-
250:1233-1238, 1990
-
Malkin D, Li FP, Stong LC, Fraumeni JF, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischof FZ, Tainsky MA, Friend S, H: Germline p53 mutations in a familial syndrome of breast cancer, sarcomas and other neoplasms. Science 250:1233-1238, 1990
-
Li FP, Stong LC, Fraumeni JF, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischof FZ, Tainsky MA, Friend S, H: Germline P53 Mutations in A Familial Syndrome of Breast Cancer, Sarcomas and Other Neoplasms. Science
-
-
Malkin, D.1
-
118
-
-
0027496935
-
-
75:805-816, 1993
-
Harper JW, Adami GR, Wei NW, Keyomarsi H, Elledge S, J: The p21 Cdk-interacting, protein CIP1 is a potent inhibitor of Gl cyclin-dependent kinases. Cell 75:805-816, 1993
-
Adami GR, Wei NW, Keyomarsi H, Elledge S, J: the P21 Cdk-interacting, Protein CIP1 Is A Potent Inhibitor of Gl Cyclin-dependent Kinases. Cell
-
-
Harper, J.W.1
-
119
-
-
0027359827
-
-
75:817-825, 1993
-
El-Deiry WS, Tokino T, Velculescu VE, levy DB, Parson R, Trent JM, Lin D, Mercer EW, Kinzler KW, Vogelstein , B: WAF1 a potential mediator of p53 tumor suppression. Cell 75:817-825, 1993
-
Tokino T, Velculescu VE, Levy DB, Parson R, Trent JM, Lin D, Mercer EW, Kinzler KW, Vogelstein , B: WAF1 A Potential Mediator of P53 Tumor Suppression. Cell
-
-
El-Deiry, W.S.1
-
124
-
-
0027210981
-
-
4:42-46, 1993
-
Dittmeyer D, Pato S, Zambetti G, Chu S, Tersky AK, More M, Finlay L, Levine A, J: Gain of function p53 mutants. Nat Genet 4:42-46, 1993
-
Pato S, Zambetti G, Chu S, Tersky AK, More M, Finlay L, Levine A, J: Gain of Function P53 Mutants. Nat Genet
-
-
Dittmeyer, D.1
-
125
-
-
0025719491
-
-
8:10124-10128. 1991
-
Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten , J: A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Prof Kttl Acad Sci USA 8:10124-10128. 1991
-
Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten , J: A Role for Sunlight in Skin Cancer: UV-induced P53 Mutations in Squamous Cell Carcinoma. Prof Kttl Acad Sci USA
-
-
Brash, D.E.1
-
126
-
-
0026344436
-
-
4:445-449, 1991
-
Pierceall WE, Mukhopadhyay T, Goldberg LH, Ananthaswamy H, N: Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas. Mol Carcinog 4:445-449, 1991
-
Mukhopadhyay T, Goldberg LH, Ananthaswamy H, N: Mutations in the P53 Tumor Suppressor Gene in Human Cutaneous Squamous Cell Carcinomas. Mol Carcinog
-
-
Pierceall, W.E.1
-
127
-
-
0025941313
-
-
6:1785-1789, 1991
-
Gusterson B A, Anbazhagan R, Warren W, Midgely C, Lane DP, O'Hare M, Stamps A, Carter R, Jayatilake , H: Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 6:1785-1789, 1991
-
Anbazhagan R, Warren W, Midgely C, Lane DP, O'Hare M, Stamps A, Carter R, Jayatilake , H: Expression of P53 in Premalignant and Malignant Squamous Epithelium. Oncogene
-
-
Gusterson, B.A.1
-
129
-
-
0028596185
-
-
372:773-776, 1994
-
Ziegler A, Jonason AS, Leffell DJ, Simon JH, Sharma HW, Kimmelman J, Rammington L, Jacks T, Brash D, E: Sunburn and p53 in the onset of skin cancer. Nature 372:773-776, 1994
-
Jonason AS, Leffell DJ, Simon JH, Sharma HW, Kimmelman J, Rammington L, Jacks T, Brash D, E: Sunburn and P53 in the Onset of Skin Cancer. Nature
-
-
Ziegler, A.1
-
130
-
-
0021673319
-
-
312:649-651, 1984
-
Parada LF, Land H, Weinberg RA. Wolf D, Rotter , V: Cooperation between the gene encoding p53 tumor antigen and ras in cellular transformation. Nature 312:649-651, 1984
-
Land H, Weinberg RA. Wolf D, Rotter , V: Cooperation between the Gene Encoding P53 Tumor Antigen and Ras in Cellular Transformation. Nature
-
-
Parada, L.F.1
-
131
-
-
0021675797
-
-
312:646-649, 1984
-
Eliyahu D, Raz A, Gross P, Givol D, Oren , M: Participation of p53 cellular tumor antigen in transformation of normal embryonic cells. Nature 312:646-649, 1984
-
Raz A, Gross P, Givol D, Oren , M: Participation of P53 Cellular Tumor Antigen in Transformation of Normal Embryonic Cells. Nature
-
-
Eliyahu, D.1
-
132
-
-
0025611503
-
-
250:1576-1580, 1990
-
Chen PL, Chen Y, Bookstein R, Lee W, H: Genetic mechanisms of tumor suppression by the human p53 gene. Science 250:1576-1580, 1990
-
Chen Y, Bookstein R, Lee W, H: Genetic Mechanisms of Tumor Suppression by the Human P53 Gene. Science
-
-
Chen, P.L.1
-
133
-
-
0027450860
-
-
7:83-88, 1993
-
Wyllie FS, Lemolne WR, Barton CN, Dawson T, Bond J, Wynford-Thomas , D: Direct growth stimulation of normal human epithelial cells by mutant p53. Mol Cminog 7:83-88, 1993
-
Lemolne WR, Barton CN, Dawson T, Bond J, Wynford-Thomas , D: Direct Growth Stimulation of Normal Human Epithelial Cells by Mutant P53. Mol Cminog
-
-
Wyllie, F.S.1
-
134
-
-
0026636158
-
-
70:153-161, 1992
-
Lu X, Park SH, Thompson TC, Lane DP: ras induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation. Cell 70:153-161, 1992
-
Park SH, Thompson TC, Lane DP: Ras Induced Hyperplasia Occurs with Mutation of P53, but Activated Ras and Myc Together Can Induce Carcinoma Without P53 Mutation. Cell
-
-
Lu, X.1
-
135
-
-
0027203921
-
-
74:813-822, 1993
-
Kemp CJ, Donehower LA, Bradley A, Balmain , A: Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74:813-822, 1993
-
Donehower LA, Bradley A, Balmain , A: Reduction of P53 Gene Dosage Does Not Increase Initiation or Promotion but Enhances Malignant Progression of Chemically Induced Skin Tumors. Cell
-
-
Kemp, C.J.1
-
137
-
-
0028072523
-
-
79:329-339, 1994
-
Strasser A, Harris AW, Jacks T, Cory , S: DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell 79:329-339, 1994
-
Harris AW, Jacks T, Cory , S: DNA Damage Can Induce Apoptosis in Proliferating Lymphoid Cells Via P53-independent Mechanisms Inhibitable by Bcl-2. Cell
-
-
Strasser, A.1
-
138
-
-
0028068167
-
-
54:3714-3717, 1994
-
Pietenpol JA, Papadopoulos N, Markowitz S, Willson HKV, Kinzler KW, Vogelstein , B: Paradoxical inhibition of solid tumor cell growth by Bcl-2. Cancer Res 54:3714-3717, 1994
-
Papadopoulos N, Markowitz S, Willson HKV, Kinzler KW, Vogelstein , B: Paradoxical Inhibition of Solid Tumor Cell Growth by Bcl-2. Cancer Res
-
-
Pietenpol, J.A.1
-
139
-
-
0028043901
-
-
53-independent pathway for upregulation of SDIl/ClPI/WAFI/p21 RNA in human cells. AM Carcinog 11:59-65, 1994
-
Johnson M, Dimitrov D, Vojta PJ, Barrett JC, Noda A, Pereira-Smith OM, Smith J, R: Evidence for a 53-independent pathway for upregulation of SDIl/ClPI/WAFI/p21 RNA in human cells. AM Carcinog 11:59-65, 1994
-
Dimitrov D, Vojta PJ, Barrett JC, Noda A, Pereira-Smith OM, Smith J, R: Evidence for A
-
-
Johnson, M.1
-
140
-
-
33745544738
-
-
1994, pp 475-484
-
Greenhalgh DA, Rothnagel JA, Wang XJ, Dominey AM, Roop D, R: Transgenic models for inherited and acquired skin disorders. In: Watt F, Lane B, Leigh I (eds.). Tlie Keratinocyte Handbook. Cambridge University Press, 1994, pp 475-484
-
Rothnagel JA, Wang XJ, Dominey AM, Roop D, R: Transgenic Models for Inherited and Acquired Skin Disorders. In: Watt F, Lane B, Leigh i (Eds.). Tlie Keratinocyte Handbook. Cambridge University Press
-
-
Greenhalgh, D.A.1
-
141
-
-
33745569794
-
-
1994, pp 317-330
-
Greenhalgh DA, Wang XJ, Dominey AM, Rothnagel JA, Roop D, R: Transgenic models for skin carcinogenesis. In: Mukhtar H (ed.). Skin Cancer Mechanisms and Human Relevance. CRC Dermatology Series, CRC, 1994, pp 317-330
-
Wang XJ, Dominey AM, Rothnagel JA, Roop D, R: Transgenic Models for Skin Carcinogenesis. In: Mukhtar H (Ed.). Skin Cancer Mechanisms and Human Relevance. CRC Dermatology Series, CRC
-
-
Greenhalgh, D.A.1
|