The role of p27(kip1) in the in vitro differentiation of murine keratinocytes

Cell Growth and Differentiation

Volumn 8, Issue 2, 1997, Pages 203-211

  Hauser, Paul J ^a   Agrawal, Deepak ^b   Flanagan, Mike ^d   Pledger, W Jack ^b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CYCLIN A; CYCLINE; PHOSPHOTRANSFERASE; ANTISENSE OLIGONUCLEOTIDE; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MICROTUBULE ASSOCIATED PROTEIN; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL CYCLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; ENZYME ACTIVITY; GROWTH DISORDER; IMMUNE COMPLEX DISEASE; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; CELL ADHESION; CYTOLOGY; ENZYME INDUCTION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOUSE; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL ADHESION; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME INDUCTION; KERATINOCYTES; MICE; MICE, INBRED ICR; MICROTUBULE-ASSOCIATED PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEINS;

EID: 0030614671     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Heichman, K. A., and Roberts, J. M. Rules to replicate by. Cell 79: 557-562, 1994.
2. Sherr, C. J. G1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
3. Draetta, G. F. Mammalian G1 cyclins. Curr. Opin. Cell Biol., 6: 842-846, 1994.
4. Kato, J. Y., Matsuoka, M., Strom, D. K., and Sherr, C. J. Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol. Cell. Biol., 14:2713-2721, 1994.
5. Matsuoka, M., Kato, R., Fisher, R. P., Morgan, D., and Sherr, C. J. Activation of cyclin dependent-kinase-4 (cdk4) by mouse MO15-associated kinase. Mol. Cell. Biol., 14: 7265-7275, 1994.
6. EI-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. WAF1, a potential mediator of p53 tumor suppression. Cell, 75:817-825, 1993.
7. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. The p21 Cdk-interact ing protein Cip1 is a potent inhibitor of G1 cyclindependent kinases. Cell, 75: 805-816, 1993.
8. Polyak, K., Lee, M. H., Erdjument-Bromage, H., Koff, A., Roberts, J. M., Tempst, P., and Massagué, J. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell, 78: 59-66, 1994.
9. Lee, M. H., Reynisdottir, I., and Massagué, J. Cloning of p57Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev., 9: 639-649, 1995.
10. Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., and Elledge, S. J. p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev., 9: 650-662, 1995.
11. Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.) 366: 704-707, 1993.
12. Hirai, H., Roussel, M. F., Kato, J. Y., Ashmun, R. A., and Sherr, C. J. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. Cell. Biol., 15: 2672-2681, 1995.
13. Sherr, C., and Roberts, J. Inhibitors of mammalian G1 cyclin dependent kinases. Genes Dev., 9: 1149-1163, 1995.
14. Polyak, K., Kato, J., Solomon, M. J., Sherr, C. J., Massagué, J., Roberts, J. M., and Koff, A. p27kip, a cyclin-cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8:9-22, 1994.
15. kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts. J. Biol. Chem., 271: 11253-11260, 1996.
16. Soos, T. J., Kiyokawa, H., Yan, J. S., Rubin, M. S., Giordano, A., DeBlasio, A., Bottega, S., Wong, B., Mendelsohn, J., and Koff, A. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth & Differ., 7: 135-146, 1996.
17. Kranenburg, O., Scharnhorst, V., Van der Eb, A. J., and Zantema, A. Inhibition of cyclin dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells J. Cell Biol., 131: 227-234, 1995.
18. Missero, C., Calautti, E., Eckner, R., Chin, J., Tsai, L. H., Livingston, D. M., and Dotto, G. P. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. USA, 92: 5451-5455, 1995.
19. Nelson, W. G., and Sun, T. T. The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J. Cell Biol., 97: 244-251, 1983.
20. Eichner, R., Bonitz, P., and Sun, T. T. Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J. Cell Biol., 98: 1388-1396, 1984.
21. Drozdoff, V., and Pledger, W. J. Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations. J. Cell Biol., 123: 909-919, 1993.
22. Drozdoff, V., Wall, N. A., and Pledger, W. J. Expression and growth inhibitory effect of decapentaplegic Vg-related protein 6: evidence for a regulatory role in keratinocyte differentiation. Proc. Natl. Acad. Sci. USA, 91: 5528-5532, 1994.
23. Fuchs, E. Epidermal differentiation: the bare essentials. J. Cell Biol., 111: 2807-2814, 1990.
24. Rice, R. H., and Green, H. Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell, 18: 681-694, 1979.
25. Potten, C. S., and Morris, R. J. Epithelial stem cells in vivo. J. Cell Sci., 10:45-62, 1988.
26. Watt, F. M., Jordan, P. W., and O'Neill, C. H. Cell shape controls terminal differentiation of human epidermal keratinocytes. Proc. Natl. Acad. Sci. USA, 85: 5576-5580, 1988.
27. Green, H. Terminal differentiation of cultured human epidermal cells. Cell, 11: 405-416, 1977.
28. Adams, J. C., and Watt, F. M. Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature (Lond.), 340: 307-309, 1989.
29. Wilke, M., Hsu, B., Wille, J., Pittelkow, M., and Scott, R. Biologic mechanisms for the regulation of normal human keratinocyte proliferation and differentiation. Am. J. Path., 131: 171-180, 1988.
30. Pittelkow, M. R., Wille, J. J., Jr., and Scott, R. E. Two functionally distinct classes of growth arrest states in human prokeratinocytes that regulate clonogenic potential. J. Invest. Dermatol., 86: 410-417, 1986.
31. Zhu, X., Ohtsubo, M., Bohmer, R., Roberts, J., and Assotan, R. Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol., 133: 391-403, 1996.
32. Kiyokawa, H., Kineman, R., Manova-Todorova, K., Soares, V., Hoffman, E., Ono, M., Khanam, D., Mayday, A., Frohman, L., and Koff, A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27Kip1. Cell, 85: 721-732, 1996.
33. Fero, M., Rivkin, M., Tasch, M., Porter, P., Carow, C., Firpo, E., Polyak, K., Tsai, L., Broudy, V., Perlmutter, R., Kawshamsky, K., and Roberts, J. M. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient Mice. Cell, 85:733-744, 1996.
34. kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell, 85: 707-720, 1996.
35. Agrawal, D. K., Dong, F., Wang, Y. Z., Kayda, D., and Pledger, W. J. Regulation of cyclin E and p27kip during mitosis in BALB/c 3T3 cells. Cell Growth & Differ. 6: 1199-1205, 1995.
36. kip1 cyclin-dependent kinase inhibitor prevented by rapamyacin. Nature (Lond.), 372: 570-573, 1995.
37. Agrawal, D., Hauser, P., McPherson, F., Dong, F., Garcia, A., and Pledger, W. J. Repression of p27kip synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol. Cell. Biol., 16: 4327-4336, 1996.
38. Adams, J. C., and Watt, F. M. Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature (Lond.), 340: 307-309, 1989.
39. Watt, F. Involucrin and other markers of keratinocyte terminal differentiation. J. Invest. Dermatatol., 81: 100s-103s, 1983.
40. Guo, K., Wang, J., Andres, V., Smith, R. C., and Walsh, K. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Moi. Cell. Biol., 15: 3823-3829, 1995.
41. Halevy, Q., Novitch, B- G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., and Lassar, A. B. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD, Science (Washington DC), 267: 1018-1021, 1995.
42. Jiang, H., Lin, J., Su, Z. Z., Collart, F. R., Huberman, E., and Fisher, P. B. Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence ofp53. Oncogene, 9: 3397-3406, 1994.
43. Kiyokawa, H., Richon, V. M., Rifkind, R. A., and Marks, P. A. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Mol. Cell. Biol., 14: 7195-7203, 1994.
44. Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., and Jacks, T. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev. 9: 935-944, 1995.
45. Parker, S. B., Eichele, G., Zhang, P., Rawls, A., Sands, A. T., Bradley, A., Olson, E. N., Harper, J. W., and Elledge, S. J. p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science (Washington DC), 267: 1024-1027, 1995.
46. Steinman, R. A., Hoffman, B., Iro, A., Guillouf, C., Liebermann, D. A., and el-Houseini, M. E. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene, 9: 3389-3396, 1994.
47. Fang, F., Orend, G., Watanabe, N., Hunter, T., and Ruoslahti, E. Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science (Washington DC), 271: 499-502, 1996.
48. kip1 for restriction point control of the fibroblast cell cycle. Science (Washington DC), 272: 877-880, 1996.
49. Olson, J., Winston, J., Whitlock, J., and Pledger, W. J. Cell cycle-dependent gene expression in V point-arrested BALB/c 3T3 cells. J. Cell. Physiol., 154: 333-342, 1993.
50. Winston, J., Wang, Y. Z., and Pledger, W. J. Regulation of the cell cycle machinery by oncogenic ras. Oncogene, 12: 127-134, 1996.