Tumor suppression by p27(kip1) and p21(Cip1) during chemically induced skin carcinogenesis

Oncogene

Volumn 18, Issue 33, 1999, Pages 4689-4698

  Philipp, Jeannette ^a   Vo, Khoa ^a   Gurley, Kay E ^a   Seidel, Kristy ^a   Kemp, Christopher J ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

H ras; Intestinal neoplasia; p21(Cip1); p27(Kip1); p53; Tumor promotion

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; DIMETHYLBENZ[A]ANTHRACENE; PHORBOL 12 ACETATE 13 MYRISTATE; PROTEIN P21; PROTEIN P27; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CDKN1A PROTEIN, MOUSE; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; MICROTUBULE ASSOCIATED PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR SUPPRESSOR PROTEIN;

ADENOMA; ANAPLASTIC CARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE MUTATION; GROWTH RATE; INTESTINE TUMOR; KERATINOCYTE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; ONCOGENE RAS; PAPILLOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN CARCINOGENESIS; SKIN CARCINOMA; SPINDLE CELL CARCINOMA; TUMOR SUPPRESSOR GENE; ANIMAL; CARCINOMA; CELL TRANSFORMATION; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; SKIN TUMOR;

ANIMALIA;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADENOMA; ANIMALS; CARCINOGENS; CARCINOMA; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; GENES, RAS; GENES, TUMOR SUPPRESSOR; INTESTINAL NEOPLASMS; KERATINOCYTES; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; PAPILLOMA; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TUMOR SUPPRESSOR PROTEINS;

EID: 0033584257     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202840     Document Type: Article

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