Sp1 Plays a Critical Role in the Transcriptional Activation of the Human Cyclin-dependent Kinase Inhibitor p21WAF1/Cip1 Gene by the p53 Tumor Suppressor Protein

Journal of Biological Chemistry

Volumn 276, Issue 31, 2001, Pages 29116-29125

  Koutsodontis, George ^d   Tentes, Ioannis ^a,b   Papakosta, Paraskevi ^d   Moustakas, Aristidis ^a   Kardassis, Dimitris ^c  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^b DEMOCRITUS UNIVERSITY OF THRACE MEDICAL SCHOOL   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL BONDS; CYTOLOGY; ENZYME INHIBITION; IMMUNOLOGY; MUTAGENESIS; PROTEINS; TUMORS;

COIMMUNOPRECIPITATION ASSAYS; TRANSCRIPTIONAL ACTIVATION;

GENES;

CYCLIN DEPENDENT KINASE INHIBITOR; GLUTATHIONE TRANSFERASE; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR SP1; TUMOR SUPPRESSOR PROTEIN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ENZYME INHIBITOR; HYBRID PROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH; DNA REPAIR; DROSOPHILA; GENE ACTIVATION; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; TRANSACTIVATION; ANIMAL; CELL CULTURE; CELL LINE; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; GENETIC TRANSFECTION; GENETICS; KERATINOCYTE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; OSTEOSARCOMA; PROMOTER REGION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TUMOR SUPPRESSOR GENE;

ANIMALIA;

ANIMALS; BASE SEQUENCE; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CELL LINE; CLONING, MOLECULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DROSOPHILA MELANOGASTER; ENZYME INHIBITORS; ESCHERICHIA COLI; GENES, P53; GENES, REPORTER; HUMANS; KERATINOCYTES; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGONUCLEOTIDE PROBES; OSTEOSARCOMA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SP1 TRANSCRIPTION FACTOR; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035800746     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104130200     Document Type: Article

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