-
1
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
2
-
-
0030933277
-
Oncoprotein networks
-
(1997)
Cell
, vol.88
, pp. 333-346
-
-
Hunter, T.1
-
14
-
-
0034605438
-
Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: Antiproliferative activity on human breast carcinoma cell lines
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1573-1581
-
-
Mandler, R.1
Wu, C.2
Sausville, E.A.3
Roettinger, A.J.4
Newman, D.J.5
Ho, D.K.6
King, C.R.7
Yang, D.8
Lippman, M.E.9
Landolfi, N.F.10
Dadachova, E.11
Breehbiel, M.W.12
Waldmann, T.A.13
-
17
-
-
0030961889
-
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
-
(1997)
Nat. Med.
, vol.3
, pp. 632-638
-
-
Selivanova, G.1
Iotsova, V.2
Okan, I.3
Fritsche, M.4
Strom, M.5
Groner, B.6
Grafstrom, R.C.7
Wilman, K.G.8
-
19
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
(1999)
Nat. Med.
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Kurachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.8
Meyerson, M.9
Weinberg, R.A.10
-
20
-
-
0031015772
-
Phase I clinical and pharmacokinetic study of oral carboxyamidotriazole, a signal transduction inhibitor
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 781-789
-
-
Berlin, J.1
Tutsch, K.D.2
Hutson, P.3
Cleary, J.4
Rago, R.P.5
Arzoomanian, R.Z.6
Alberti, D.7
Feierabend, C.8
Wilding, G.9
-
21
-
-
0032940051
-
Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 1095-1104
-
-
Eckhardt, S.G.1
Rizzo, J.2
Sweeney, K.R.3
Cropp, G.4
Baker, S.D.5
Kraynak, M.A.6
Kuhn, J.G.7
Villalona-Calero, M.A.8
Hammond, L.9
Weiss, G.10
Thurman, A.11
Smith, L.12
Drengler, R.13
Eckardt, J.R.14
Moczygemba, J.15
Hannah, A.L.16
Von Hoff, D.D.17
Rowinsky, E.K.18
-
22
-
-
0032862225
-
A Phase II study of high-dose tamoxifen in patients with hormone- refractory prostate cancer
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2366-2373
-
-
Bergan, R.C.1
Reed, E.2
Myers, C.E.3
Headlee, D.4
Brawley, O.5
Cho, H.K.6
Figg, W.D.7
Tompkins, A.8
Linehan, W.M.9
Kohler, D.10
Steinberg, S.M.11
Blagosklonny, M.V.12
-
24
-
-
0033955395
-
Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: A University of Chicago Phase II Consortium study
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 371-375
-
-
Stadler, W.M.1
Vogelzang, N.J.2
Amato, R.3
Sosman, J.4
Taber, D.5
Liebowitz, D.6
Vokes, E.E.7
-
27
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
28
-
-
0028579733
-
Oncogenes and the strategy of growth factors
-
(1994)
Cell
, vol.79
, pp. 927-930
-
-
Baserga, R.1
-
31
-
-
0033551066
-
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4325-4329
-
-
Chen, Y.-N.P.1
Sharma, S.K.2
Ramsey, T.M.3
Jiang, L.4
Martin, M.S.5
Baker, K.6
Adams, P.D.7
Bair, K.W.8
Kaelin W.G., Jr.9
-
36
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
(1998)
Science (Wash. DC)
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
37
-
-
0029050533
-
Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5436-5440
-
-
Almasan, A.1
Yin, Y.2
Kelly, R.E.3
Lee, E.Y.4
Bradley, A.5
Li, W.6
Bertino, J.R.7
Wahl, G.M.8
-
40
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
(1999)
J. Clin. Investig.
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Dutriaux, A.8
Lengauer, C.9
Kinzler, K.W.10
Vogelstein, B.11
-
42
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
49
-
-
0032509403
-
UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee I Hu kinase and activation of the Cdc25C phosphatase
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33455-33464
-
-
Yu, L.1
Orlandi, L.2
Wang, P.3
Orr, M.S.4
Senderowicz, A.M.5
Sausville, E.A.6
Silvestrini, R.7
Watanabe, N.8
Piwnica-Worms, H.9
O'Connor, P.M.10
-
54
-
-
0034614334
-
A long twentieth century of the cell cycle and beyond
-
(2000)
Cell
, vol.100
, pp. 71-78
-
-
Nurse, P.1
-
60
-
-
0031938204
-
Sequence-dependent hematological toxicity associated with the 3-hour paclitaxel/cyclophosphamide doublet
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 349-356
-
-
Kennedy, M.J.1
Zahurak, M.L.2
Donehower, R.C.3
Noe, D.4
Grochow, L.B.5
Sartorius, S.6
Chen, T.L.7
Bowling, K.8
Duerr, M.9
Rowinsky, E.K.10
-
61
-
-
0031782882
-
Superiority of sequential versus concurrent administration of paclitaxel with etoposide in advanced non-small cell lung cancer: Comparison of two phase II trials
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2723-2728
-
-
Felip, E.1
Massuti, B.2
Camps, C.3
Benito, D.4
Isla, D.5
Gonzalez-Larriba, J.L.6
Lopez-Cabrerizo, M.P.7
Salamanca, O.8
Puerto-Pica, J.9
Moyano, A.10
Baselga, J.11
Rosell, R.12
-
74
-
-
0034629485
-
Reversible G1 arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27K1P1 independent of MAPK activity
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6987-6995
-
-
Busse, D.1
Doughty, R.S.2
Ramsey, T.T.3
Russell, W.E.4
Price, J.O.5
Flanagan, W.M.6
Shawver, L.K.7
Arteaga, C.L.8
-
80
-
-
0034694674
-
Protection of normal proliferating cells against chemotherapy by staurosporine-mediated, selective, and reversible G1 arrest
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1999-2008
-
-
Chen, X.1
Lowe, M.2
Herliczek, T.3
Hall, M.J.4
Danes, C.5
Lawrence, D.A.6
Keyomarsi, K.7
-
82
-
-
0028129539
-
Recombinant transforming growth factor β1 and β2 protect mice from acutely lethal doses of 5-fluorouracil and doxorubicin
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1047-1057
-
-
Grzegorzewski, K.1
Ruscetti, F.W.2
Usui, N.3
Damia, G.4
Longo, D.L.5
Carlino, J.A.6
Keller, J.R.7
Wiltrout, R.H.8
-
91
-
-
0034660892
-
The Pezcoller lecture: Cancer cell cycle revisited
-
(2000)
Cancer Res.
, vol.60
, pp. 3689-3695
-
-
Sherr, C.J.1
-
92
-
-
0035808599
-
Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors
-
(2001)
Science (Wash. DC)
, vol.291
, pp. 134-137
-
-
Davis, S.T.1
Benson, B.G.2
Bramson, H.N.3
Chapman, D.E.4
Dickerson, S.H.5
Dold, K.M.6
Eberwein, D.J.7
Edelstein, M.8
Frye, S.V.9
Gampe, R.T.10
Griffin, R.J.11
Harris, P.A.12
Hassel, A.M.13
Holmes, W.D.14
Hunter, R.N.15
Knick, V.B.16
Lackey, K.17
Lovejoy, B.18
Luzzio, M.J.19
Murray, D.20
Parker, P.21
Rocque, W.J.22
Shewchuk, L.23
Veal, J.M.24
Walker, D.H.25
Kuyper, L.F.26
more..
-
94
-
-
0032852874
-
RB status as a determinant of response to UCN-01 in non-small cell lung carcinoma
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2596-2604
-
-
Mack, P.C.1
Gandara, D.R.2
Bowen, C.3
Edelman, M.J.4
Paglieroni, T.5
Schnier, J.B.6
Gelmann, E.P.7
Gumerlock, P.H.8
-
95
-
-
0033522231
-
Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21 (WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity
-
(1999)
Oncogene
, vol.18
, pp. 1663-1676
-
-
Schreiber, M.1
Muller, W.J.2
Singh, G.3
Graham, F.L.4
-
96
-
-
0032715399
-
Drug-resistance enables selective killing of resistant leukemia cells: Exploiting of drug resistance instead of reversal
-
(1999)
Leukemia (Baltimore)
, vol.13
, pp. 2031-2035
-
-
Blagosklonny, M.V.1
|