-
1
-
-
0032891070
-
The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans
-
(1999)
J. Bacteriol.
, vol.181
, pp. 700-708
-
-
Alarco, A.M.1
Raymond, M.2
-
4
-
-
0032321894
-
Drug-stimulatable ATPase activity in crude membranes of human MDR1-transfected mammalian cells
-
(1998)
Methods Enzymol.
, vol.292
, pp. 504-514
-
-
Ambudkar, S.V.1
-
6
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
(1999)
Ann. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandran, M.4
Pastan, I.5
Gottesman, M.M.6
-
21
-
-
0028111508
-
Molecular cloning and expression of Saccharomyces cerevisiae STS1 gene product, a yeast ABC transporter conferring mycotoxin resistance
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4180-4186
-
-
Bissinger, P.H.1
Kuchler, K.2
-
23
-
-
0033914401
-
Novel approaches in the rational design of antifungal agents of low toxicity
-
(2000)
Farmaco.
, vol.55
, pp. 206-208
-
-
Borowski, E.1
-
25
-
-
0345009005
-
FLR1 gene (ORFYBR008c) is required for benomyl and methotrexate resistance in Saccharomyces cerevisiae and its benomyl induced expression is dependent on Pdr3 transcriptional regulator
-
(1999)
Yeast
, vol.15
, pp. 1595-1608
-
-
Broco, N.1
Tenreiro, S.2
Viegas, C.A.3
Sa-Correja, I.4
-
26
-
-
0032491154
-
Binding and reactivity of Candida albicans estrogen binding protein with steroid and other substrates
-
(1998)
Biochemistry
, vol.37
, pp. 14326-14336
-
-
Buckman, J.1
Miller, S.M.2
-
43
-
-
0029073576
-
Identification and characterisation of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18150-18157
-
-
Decottignies, A.1
Lambert, L.2
Catty, P.3
Degand, H.4
Eppings, E.A.5
Moye-Rowley, W.S.6
Balzi, E.7
Goffeau, A.8
-
50
-
-
0028154080
-
Mutations in the yeast PDR3, PDR4, PDR7 pleiotropic (multiple) drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5
-
(1994)
Genetics
, vol.136
, pp. 505-515
-
-
Dexter, D.1
Rowley, S.M.2
Wu, A.3
Golin, J.4
-
53
-
-
0033616421
-
Asymmetric distribution of phosphatidylethanolamine in C. albicans: Possible mediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily
-
(1999)
Yeast
, vol.15
, pp. 111-121
-
-
Dogra, S.1
Krishnamurthy, S.2
Gupta, V.3
Dixit, B.L.4
Gupta, C.M.5
Sanglard, D.6
Prasad, R.7
-
62
-
-
0033969525
-
Analysis of the tangled relationships between P-glycoprotein-mediated mutlidrug resistance and the lipid phase of the cell membrane
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 277-294
-
-
Ferte, J.1
-
70
-
-
0025299317
-
Allelism of SNQ1 and ATR1, genes of the yeast Saccharomyces cerevisiae required for sensitivity to 4-nitroquinoline-N-oxide and aminotriazole
-
(1990)
Curr. Genet.
, vol.18
, pp. 93-96
-
-
Gompel-Klein, P.1
Brendel, M.2
-
71
-
-
0027932666
-
Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response
-
(1994)
EMBO J.
, vol.13
, pp. 4036-4041
-
-
Gounalaki, N.1
Thireos, G.2
-
73
-
-
0031692037
-
Identification of mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance and its in vitro transcriptional activation
-
(1998)
Curr. Genet.
, vol.34
, pp. 192-199
-
-
Gupta, V.1
Kohli, A.K.2
Krishnamurthy, S.3
Puri, N.4
Aalamgeer, S.A.5
Panwar, S.L.6
Prasad, R.7
-
75
-
-
0023840065
-
Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1454-1458
-
-
Hamada, H.1
Tsururo, T.2
-
77
-
-
0035971152
-
Energy-dependent flip of fluorescent-labeled phospholipids is regulated by nutrient starvation and transcription factors, PDR1 and PDR3
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9861-9867
-
-
Hanson, P.K.1
Nicholas, J.W.2
-
94
-
-
0032957488
-
The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae
-
(1999)
Microbiology
, vol.145
, pp. 809-818
-
-
Kaur, R.1
Bachhawat, A.K.2
-
97
-
-
0031024163
-
5,6-desaturation
-
(1997)
FEBS Lett.
, vol.400
, pp. 80-82
-
-
Kelly, S.L.1
Lamb, D.C.2
Kelly, D.E.3
Manning, N.J.4
Loeffler, J.5
Hebart, H.6
Schumacher, U.7
Einsele, H.8
-
100
-
-
0031278013
-
Active efflux by multidrug transporters as one of the strategies to evade chemotherapy and novel practical implications of yeast pleiotropic drug resistance
-
(1997)
Pharmacol. Ther.
, vol.76
, pp. 219-242
-
-
Kolaczkowski, M.1
Goffeau, A.2
-
101
-
-
0029905732
-
Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31543-31548
-
-
Kolaczkowski, M.1
Van der Rest, M.E.2
Cybularz-Kolaczkowska, A.3
Soumillion, J.-P.4
Konings, W.N.5
Goffeau, A.6
-
105
-
-
0032580522
-
Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: Expression of a yeast multidrug transporter in Baculovirus expression system
-
(1998)
Yeast
, vol.14
, pp. 535-550
-
-
Krishnamurthy, S.1
Chatterjee, U.2
Gupta, V.3
Prasad, R.4
Das, P.5
Snehlata, P.6
Hasnain, S.E.7
Prasad, R.8
-
108
-
-
0028057226
-
YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hyperoxides
-
(1994)
EMBO J.
, vol.13
, pp. 655-664
-
-
Kuge, S.1
Jones, N.2
-
109
-
-
0031054924
-
The mutation T315A in Candida albicans sterol 14αdemethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5682-5688
-
-
Lamb, D.C.1
Kelly, D.E.2
Schunck, W.-H.3
Shyadehi, A.Z.4
Akhtar, M.5
Lowe, D.J.6
Baldwin, B.C.7
Kelly, S.L.8
-
111
-
-
0028855545
-
An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast
-
(1995)
EMBO J.
, vol.14
, pp. 188-195
-
-
Leighton, J.1
Schatz, G.2
-
112
-
-
0033067397
-
Molecular modelling of lanosterol 14αdemethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: Quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives
-
(1999)
J. Enzyme Inhibit.
, vol.14
, pp. 175-192
-
-
Lewis, D.F.V.1
Wiseman, A.2
Tarbit, M.H.3
-
114
-
-
0027997698
-
Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein
-
(1994)
Biochemistry
, vol.33
, pp. 14049-14057
-
-
Loo, T.W.1
Clarke, D.M.2
-
115
-
-
0029909604
-
Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM 12 of human P-glycoprotein by drug substrates
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27482-27487
-
-
Loo, T.W.1
Clarke, D.M.2
-
118
-
-
0033609856
-
The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24759-24765
-
-
Loo, T.W.1
Clarke, D.M.2
-
119
-
-
0034051662
-
The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5253-5256
-
-
Loo, T.W.1
Clarke, D.M.2
-
125
-
-
0030812876
-
Molecular biological characterization of an azole-resistant Candida glabrata isolate
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2229-2237
-
-
Marichal, P.1
Vanden Bossche, H.2
Odds, F.C.3
Nobels, G.4
Warnock, D.W.5
Timmerman, V.6
Van Broeckhoven, C.7
Fay, S.8
Mose-Larsen, P.9
-
126
-
-
0032826408
-
Contribution of mutations in the cytochrome P450 14α-demethylase (Erg 11p Cyp51p) to azole resistance in Candida albicans
-
(1999)
Microbiology
, vol.145
, pp. 2701-2713
-
-
Marichal, P.1
Koymans, L.2
Willemsens, S.3
Bellens, D.4
Verhasselt, P.5
Luyten, W.6
Borgers, M.7
Ramaekers, F.C.S.8
Odds, F.C.9
Vanden Bossche, H.10
-
132
-
-
0031807604
-
Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 1695-1701
-
-
Miyazaki, H.1
Miyazaki, Y.2
Geber, A.3
Parkinson, T.4
Hitchcock, C.A.5
Falconer, D.J.6
Ward, D.J.7
Marsden, K.8
Bennett, J.E.9
-
137
-
-
0035100252
-
Chs 1 of Candida albicans is an essential chitin synthase required for synthesis of the septum and for cell integrity
-
(2001)
Mol. Microbiol.
, vol.39
, pp. 1414-1426
-
-
Munro, C.A.1
Winter, K.2
Buchan, A.3
Henry, K.4
Becker, J.M.5
Brown, A.J.P.6
Bulawa, C.E.7
Gow, N.A.R.8
-
138
-
-
0028957971
-
+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily
-
(1995)
J. Bacteriol.
, vol.177
, pp. 1536-1543
-
-
Nagao, K.1
Taguchi, Y.2
Arioka, M.3
Kadokura, H.4
Takatsuki, A.5
Yoda, K.6
Yamasaki, M.7
-
149
-
-
0032996479
-
YAP1 confers resistance to the fatty acid synthase inhibitor cerulenin through the transporter Flr1p in Saccharomyces cerevisiae
-
(1999)
Mol. Gen. Genet.
, vol.261
, pp. 346-353
-
-
Oskouian, B.1
Saba, J.D.2
-
150
-
-
0034834285
-
CaALK8, an alkane assimilating cytochrome P450 confers multiple drug resistance when expressed in a hypersensitive strain of Candida albicans
-
(2000)
Yeast
, vol.18
, pp. 1117-1129
-
-
Panwar, S.L.1
Krishnamurthy, S.2
Gupta, V.3
Alarco, A.-M.4
Raymond, M.5
Sanglard, D.6
Prasad, R.7
-
153
-
-
0032987324
-
Specific chromosome alterations in fluconazole-resistant mutants of Candida albicans
-
(1999)
J. Bacteriol.
, vol.181
, pp. 4041-4049
-
-
Perepnikhatka, V.1
Fischer, F.J.2
Niimi, M.3
Baker, R.A.4
Cannon, R.D.5
Wang, Y.-K.6
Sherman, F.7
Rustchenko, E.8
-
154
-
-
0032479995
-
The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast
-
(1998)
EMBO J.
, vol.17
, pp. 4257-4265
-
-
Piper, P.1
Mahe, Y.2
Thompson, S.3
Pandjaitan, R.4
Holyoak, C.5
Egner, R.6
Muhlbauer, M.7
Coote, P.8
Kuchler, K.9
-
160
-
-
0028307550
-
Phosphatidylcholine translocase: A physiological role for the mdr2 gene
-
(1994)
Cell
, vol.77
, pp. 1071-1081
-
-
Ruetz, S.1
Gros, P.2
-
171
-
-
0002424707
-
Analysis of the ATP-binding cassette (ABC)-transporter gene CDR4 from Candida albicans
-
Charleston, South Carolina, USA, 1-4 March
-
(1999)
ASM Conference on Candida and Candidiasis
, pp. 56
-
-
Sanglard, D.1
Ischer, F.2
Monod, M.3
Dogra, S.4
Prasad, R.5
Bille, J.6
-
176
-
-
0027497594
-
Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases
-
(1993)
Mol. Gen. Genet.
, vol.236
, pp. 214-218
-
-
Servos, J.1
Haase, E.2
Brendel, M.3
-
188
-
-
0032902758
-
Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae
-
(1999)
J. Bacteriol.
, vol.181
, pp. 231-240
-
-
Talibi, D.1
Raymond, M.2
-
195
-
-
0026487058
-
Human P-glycoprotein transports cortisol, aldosterone and dexamethasone, but not progesterone
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24248-24252
-
-
Ueda, K.1
Okamura, N.2
Hirai, M.3
Tanigawara, Y.4
Saeki, T.5
Kioka, N.6
Komano, T.7
Hori, R.8
-
199
-
-
0000942202
-
PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1934-1941
-
-
Van Den Hazel, H.B.1
Pichler, H.2
Do Valle Matta, M.A.3
Leitner, E.4
Goffeau, A.5
Daum, G.6
-
200
-
-
0007544439
-
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
-
(1996)
Cell
, vol.87
, pp. 507-517
-
-
Van Helvoort, A.1
Smith, A.J.2
Sprong, H.3
Fritzche, I.4
Schinkel, A.H.5
Borst, P.6
Van Meer, G.7
-
203
-
-
0024942128
-
Biochemical approaches to selective antifungal activity, focus on azole antifungals
-
(1989)
Mycoses
, vol.32
, pp. 35-52
-
-
Vanden Bossche, H.1
Marichal, P.2
Gorrens, J.3
Coene, M.-C.4
Willemsens, G.5
Bellens, D.6
Roels, I.7
Moereels, H.8
Janssen, P.A.J.9
-
205
-
-
84907129560
-
Mechanisms and clinical impact of antifungal drug resistance
-
(1994)
J. Med. Vet. Mycol.
, vol.32
, pp. 189-202
-
-
Vanden Bossche, H.1
Warnock, D.G.2
Dupont, B.3
Kerridge, D.4
Sengupta, S.5
Improvisi, L.6
Marichal, P.7
Odds, F.C.8
Provost, F.9
Ronin, O.10
-
210
-
-
0030757227
-
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increased azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1482-1487
-
-
White, T.C.1
-
211
-
-
0030792602
-
The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α demethylase in Candida albicans
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1488-1494
-
-
White, T.C.1
|