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Volumn 46, Issue , 2002, Pages 155-201

Drug resistance in yeasts - An emerging scenario

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMILORIDE; AMINOTRIAZOLE; AMOROLFINE; AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; BENOMYL; BREFELDIN A; CERULENIN; CHLORAMPHENICOL; CRYSTAL VIOLET; CYCLOHEXIMIDE; DACTINOMYCIN; ECHINOCANDIN B; ERGOSTEROL; ETHIDIUM BROMIDE; FLUCONAZOLE; FLUCYTOSINE; FLUPHENAZINE; KETOCONAZOLE; MESYLIC ACID METHYL ESTER; METHOTREXATE; MYCOPHENOLIC ACID; TERBINAFINE; TETRACENOMYCIN C; TETRACYCLINE; UNINDEXED DRUG; VANCOMYCIN;

EID: 0035985631     PISSN: 00652911     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2911(02)46004-3     Document Type: Review
Times cited : (65)

References (223)
  • 1
    • 0032891070 scopus 로고    scopus 로고
    • The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans
    • (1999) J. Bacteriol. , vol.181 , pp. 700-708
    • Alarco, A.M.1    Raymond, M.2
  • 4
    • 0032321894 scopus 로고    scopus 로고
    • Drug-stimulatable ATPase activity in crude membranes of human MDR1-transfected mammalian cells
    • (1998) Methods Enzymol. , vol.292 , pp. 504-514
    • Ambudkar, S.V.1
  • 21
    • 0028111508 scopus 로고
    • Molecular cloning and expression of Saccharomyces cerevisiae STS1 gene product, a yeast ABC transporter conferring mycotoxin resistance
    • (1994) J. Biol. Chem. , vol.269 , pp. 4180-4186
    • Bissinger, P.H.1    Kuchler, K.2
  • 23
    • 0033914401 scopus 로고    scopus 로고
    • Novel approaches in the rational design of antifungal agents of low toxicity
    • (2000) Farmaco. , vol.55 , pp. 206-208
    • Borowski, E.1
  • 25
    • 0345009005 scopus 로고    scopus 로고
    • FLR1 gene (ORFYBR008c) is required for benomyl and methotrexate resistance in Saccharomyces cerevisiae and its benomyl induced expression is dependent on Pdr3 transcriptional regulator
    • (1999) Yeast , vol.15 , pp. 1595-1608
    • Broco, N.1    Tenreiro, S.2    Viegas, C.A.3    Sa-Correja, I.4
  • 26
    • 0032491154 scopus 로고    scopus 로고
    • Binding and reactivity of Candida albicans estrogen binding protein with steroid and other substrates
    • (1998) Biochemistry , vol.37 , pp. 14326-14336
    • Buckman, J.1    Miller, S.M.2
  • 28
    • 0033677649 scopus 로고    scopus 로고
    • A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole
    • (2000) Microbiology , vol.146 , pp. 2743-2754
    • Calabrese, D.1    Bille, J.2    Sanglard, D.3
  • 50
    • 0028154080 scopus 로고
    • Mutations in the yeast PDR3, PDR4, PDR7 pleiotropic (multiple) drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5
    • (1994) Genetics , vol.136 , pp. 505-515
    • Dexter, D.1    Rowley, S.M.2    Wu, A.3    Golin, J.4
  • 55
  • 62
    • 0033969525 scopus 로고    scopus 로고
    • Analysis of the tangled relationships between P-glycoprotein-mediated mutlidrug resistance and the lipid phase of the cell membrane
    • (2000) Eur. J. Biochem. , vol.267 , pp. 277-294
    • Ferte, J.1
  • 70
    • 0025299317 scopus 로고
    • Allelism of SNQ1 and ATR1, genes of the yeast Saccharomyces cerevisiae required for sensitivity to 4-nitroquinoline-N-oxide and aminotriazole
    • (1990) Curr. Genet. , vol.18 , pp. 93-96
    • Gompel-Klein, P.1    Brendel, M.2
  • 71
    • 0027932666 scopus 로고
    • Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response
    • (1994) EMBO J. , vol.13 , pp. 4036-4041
    • Gounalaki, N.1    Thireos, G.2
  • 75
    • 0023840065 scopus 로고
    • Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase
    • (1988) J. Biol. Chem. , vol.263 , pp. 1454-1458
    • Hamada, H.1    Tsururo, T.2
  • 77
    • 0035971152 scopus 로고    scopus 로고
    • Energy-dependent flip of fluorescent-labeled phospholipids is regulated by nutrient starvation and transcription factors, PDR1 and PDR3
    • (2001) J. Biol. Chem. , vol.276 , pp. 9861-9867
    • Hanson, P.K.1    Nicholas, J.W.2
  • 94
    • 0032957488 scopus 로고    scopus 로고
    • The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae
    • (1999) Microbiology , vol.145 , pp. 809-818
    • Kaur, R.1    Bachhawat, A.K.2
  • 100
    • 0031278013 scopus 로고    scopus 로고
    • Active efflux by multidrug transporters as one of the strategies to evade chemotherapy and novel practical implications of yeast pleiotropic drug resistance
    • (1997) Pharmacol. Ther. , vol.76 , pp. 219-242
    • Kolaczkowski, M.1    Goffeau, A.2
  • 108
    • 0028057226 scopus 로고
    • YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hyperoxides
    • (1994) EMBO J. , vol.13 , pp. 655-664
    • Kuge, S.1    Jones, N.2
  • 111
    • 0028855545 scopus 로고
    • An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast
    • (1995) EMBO J. , vol.14 , pp. 188-195
    • Leighton, J.1    Schatz, G.2
  • 112
    • 0033067397 scopus 로고    scopus 로고
    • Molecular modelling of lanosterol 14αdemethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: Quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives
    • (1999) J. Enzyme Inhibit. , vol.14 , pp. 175-192
    • Lewis, D.F.V.1    Wiseman, A.2    Tarbit, M.H.3
  • 114
    • 0027997698 scopus 로고
    • Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein
    • (1994) Biochemistry , vol.33 , pp. 14049-14057
    • Loo, T.W.1    Clarke, D.M.2
  • 115
    • 0029909604 scopus 로고    scopus 로고
    • Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM 12 of human P-glycoprotein by drug substrates
    • (1996) J. Biol. Chem. , vol.271 , pp. 27482-27487
    • Loo, T.W.1    Clarke, D.M.2
  • 118
    • 0033609856 scopus 로고    scopus 로고
    • The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface
    • (1999) J. Biol. Chem. , vol.274 , pp. 24759-24765
    • Loo, T.W.1    Clarke, D.M.2
  • 119
    • 0034051662 scopus 로고    scopus 로고
    • The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis
    • (2000) J. Biol. Chem. , vol.275 , pp. 5253-5256
    • Loo, T.W.1    Clarke, D.M.2
  • 128
  • 129
    • 0343831467 scopus 로고    scopus 로고
    • The role of ABC transporters in antibiotic-producing organisms: Drug secretion and resistance mechanisms
    • (2001) Res. Microbiol. , vol.152 , pp. 341-350
    • Mendez, C.1    Salas, J.A.2
  • 149
    • 0032996479 scopus 로고    scopus 로고
    • YAP1 confers resistance to the fatty acid synthase inhibitor cerulenin through the transporter Flr1p in Saccharomyces cerevisiae
    • (1999) Mol. Gen. Genet. , vol.261 , pp. 346-353
    • Oskouian, B.1    Saba, J.D.2
  • 160
    • 0028307550 scopus 로고
    • Phosphatidylcholine translocase: A physiological role for the mdr2 gene
    • (1994) Cell , vol.77 , pp. 1071-1081
    • Ruetz, S.1    Gros, P.2
  • 176
    • 0027497594 scopus 로고
    • Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases
    • (1993) Mol. Gen. Genet. , vol.236 , pp. 214-218
    • Servos, J.1    Haase, E.2    Brendel, M.3
  • 188
    • 0032902758 scopus 로고    scopus 로고
    • Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae
    • (1999) J. Bacteriol. , vol.181 , pp. 231-240
    • Talibi, D.1    Raymond, M.2
  • 210
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increased azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1482-1487
    • White, T.C.1
  • 211
    • 0030792602 scopus 로고    scopus 로고
    • The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α demethylase in Candida albicans
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1488-1494
    • White, T.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.