Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5,6-desaturation

FEBS Letters

Volumn 400, Issue 1, 1997, Pages 80-82

  Kelly, S L ^a   Lamb, D C ^a   Kelly, D E ^a   Manning, N J ^b   Loeffler, J ^c   Hebart, H ^c   Schumacher, U ^d   Einsele, H ^c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

candidosis; cross resistance; fluconazole; P450 inhibition

Indexed keywords

AMPHOTERICIN B; CYTOCHROME P450; FLUCONAZOLE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CASE REPORT; CONTROLLED STUDY; CROSS RESISTANCE; DRUG RESISTANCE; ENZYME DEFICIENCY; FEMALE; HUMAN; IN VITRO STUDY; MALE; PRIORITY JOURNAL; STEROL METABOLISM;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; AMPHOTERICIN B; ANTIBIOTICS, ANTIFUNGAL; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; DRUG RESISTANCE, MICROBIAL; FEMALE; FLUCONAZOLE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; OXIDOREDUCTASES; STEROLS;

EID: 0031024163     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(96)01360-9     Document Type: Article

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