Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning

Biochemistry

Volumn 35, Issue 11, 1996, Pages 3625-3635

  Hanna, Maya ^a   Brault, Martine ^a   Kwan, Tony ^a   Kast, Christina ^a   Gros, Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSFECTION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; CHO CELLS; CRICETINAE; DNA PRIMERS; DRUG RESISTANCE, MULTIPLE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; PROTEIN STRUCTURE, SECONDARY; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0029879199     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi951333p     Document Type: Article

References (63)

1. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703.
2. Bruggemann, E. P., Germann, U. A., Gottesman, M. M., & Pastan, I. (1989) J. Biol. Chem. 264, 15483-15488.
3. Bruggemann, E. P., Currier, S. J., Gottesman, M. M., & Pastan, I. (1992) J. Biol. Chem. 267, 21020-21026.
4. Buschman, E., & Gros, P. (1991) Mol. Cell. Biol. 11, 595-603.
5. Chen, C.-j., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., & Roninson, I. B. (1986) Cell 47, 381-389.
6. Choi, K., Chen, C.-j., Kriegler, M., & Roninson, I. B. (1988) Cell 53, 519-529.
7. Cornwell, M. M., Safa, A. R., Felsted, R. L., Gottesman, M. M., & Pastan, I. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 3847-3850.
8. Cornwell, M. M., Tsuruo, T., Gottesman, M. M., & Pastan, I. (1987) FASEB J. 1, 51-54.
9. Devault, A., & Gros, P. (1990) Mol. Cell. Biol. 10, 1652-1663.
10. Devereux, J. (1991) The GCG sequence analysis software package, version 7.0, Genetics Computer Group, Inc., University Research Park, Madison, WI.
11. Devine, S. E., Ling, V., & Melera, P. W. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 4564-4568.
12. Dhir, R., & Gros, P. (1992) Biochemistry 31, 6103-6110.
13. Dhir, R., Grizzuti, K., Kajiji, S., & Gros, P. (1993) Biochemistry 32, 9492-9499.
14. Donnelly, D., & Cogdell, R. J. (1993) Protein Eng. 6, 629-635.
15. Donnelly, D., Overington, L. P., Ruffle, S. V., Nugent, J. H. A., & Blundell, T. L. (1993) Protein Sci. 2, 55-70.
16. Endicott, J. A., & Ling, V. (1989) Annu. Rev. Biochem. 58, 137-171.
17. Foote, S. J., Kyle, D. E., Martin, R. K., Oduola, A. M. J., Forsyth, K., Kemp, D. J., & Cowman, A. F. (1990) Nature 345, 255-258.
18. Gottesman, M. M., & Pastan, I. (1993) Annu. Rev. Biochem. 62, 385-427.
19. Greenberger, L. M. (1993) J. Biol. Chem. 268, 11417-11425.
20. Greenberger, L. M., Lisanti, C. J., Silva, J. T., & Horwitz, S. B. (1991) J. Biol. Chem. 266, 20744-20751.
21. Gros, P., Croop, J., & Housman, D. (1986) Cell 47, 371-380.
22. Gros, P., Raymond, M., Bell, J., & Housman, D. (1988) Mol. Cell. Biol. 8, 2770-2778.
23. Gros, P., Dhir, R., Croop, J., & Talbot, F. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 7289-7293.
24. Higgins, C. F. (1992) Annu. Rev. Cell Biol. 8, 67-113.
25. Ito, H., Fokuda, K., Murata, K., & Kimura, A. (1983) J. Bacterial. 153, 163-168.
26. Kajiji, S., Talbot, F., Grizzuti, K., Van Dyke-Phillips, V., Agresti, M., Safa, A. R., & Gros, P. (1993) Biochemistry 32, 4185-4194.
27. Kajiji, S., Dreslin, J. A., Grizzuti, K., & Gros, P. (1994) Biochemistry 33, 5041-5048.
28. Kartner, N., Evemden-Porcelle, D., Bradley, G., & Ling, V. (1985) Nature 316, 820-823.
29. Kuchler, K., & Thorner, J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 2302-2306.
30. Laemmli, U. K. (1970) Nature 227. 680-685.
31. Loo, T. W., & Clarke, D. M. (1993a) J. Biol. Chem. 268, 3143-3149.
32. Loo, T. W., & Clarke, D. M. (1993b) J. Biol. Chem. 268, 19965-19972.
33. Loo, T. W., & Clarke, D. M. (1994a) J. Biol. Chem. 269, 7243-7248.
34. Loo. T. W., & Clarke, D. M. (1994b) Biochemistry 33, 14049-14057.
35. McGrath, J. P., & Varshavsky, A. (1989) Nature 340, 400-404.
36. Morris, D. L, Speicher, L. A., Ruoho, A. E., Tew, K. D., & Seamon, K. B. (1991) Biochemistry 30, 8371-8379.
37. Morris, D. I., Greenberger, L. M., Bruggemann, E. P., Cardarelli, C., Gottesman, M. M., Pastan, I., & Seamon, K. B. (1994) Mol. Pharmacol. 46, 329-337.
38. Pawagi, A. B., Wang, J., Silverman, M., Reithmeier, R. A. F., & Deber, C. M. (1994) J. Mol. Biol. 235, 554-564.
39. Pollard, J. W., & Stanners, C. P. (1979) J. Cell Physiol. 98, 571-585.
40. Raviv, Y., Pollard, H. B., Bruggemann, E. P., Pastan, I., & Gottesman, M. M. (1990) J. Biol. Chem. 265, 3975-3980.
41. Raymond, M., Gros, P., Whiteway, M., & Thomas, D. Y. (1992) Science 256, 232-234.
42. Raymond, M., Ruetz, S., Thomas, D. Y., & Gros, P. (1994) Mol. Cell. Biol. 14, 277-286.
43. Ruetz, S., & Gros, P. (1994a) J. Biol. Chem. 269, 12277-12284.
44. Ruetz, S., & Gros, P. (1994b) Cell 77, 1071-1081.
45. Ruetz, S., Raymond, M., & Gros, P. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 11588-11592.
46. Safa. A. R., Glover, C. J., Meyers, M. B., Biedler, J. L., & Felsted, R. L. (1986) J. Biol. Chem. 261, 6137-6140.
47. Safa, A. R., Metha, N. D., & Agresti, M. (1989) Biochem. Biophys. Res. Commun. 162, 1402-1408.
48. Safa, A. R., Stem. R. K., Choi, K., Agresti, M., Tamai, L, Mehta. N. D., & Roninson, I. B. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 7225-7229.
49. Sanger, F., Nicklen, S., & Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
50. Schinkel, A. H., Roelofs, M. E. M., & Borst, P. (1991) Cancer Res. 51, 2628-2635.
51. Schinkel, A. H., Smit, J. J. M., van Tellingen, O., Beijnen, J. H., Wagenaar, E., van Deemter, L., Mol., C. A. A. M., van der Valk, M. A., Robanus-Maandag, E. C., te Riele, H. P. J., Berns, A. J. M., & Borst, P. B. (1994) Cell 77, 491-502.
52. Schurr, E., Raymond, M., Bell. J. C., & Gros, P. (1989) Cancer Res. 49, 2729-2734.
53. Shapiro, A. B., & Ling, V. (1994) J. Biol. Chem. 269, 3745-3754.
54. Shustik, C., Dalton, W., & Gros, P. (1995) Mol. Aspects Med. 76, 1-78.
55. Simon, S. M., & Schindler, M. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 3497-3504.
56. Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahan, J., Vistica, D., Warren, J., Bokesch, H., Kenny, S., & Boyd, M. R. (1989) Proc. Am. Assoc. Cancer Res. 30, 612.
57. Smith, A. J., Timmermans-Hereijgers, J. L. P. M., Roelofsen, B., Wirtz, K. W. A., van Blitterswijk, W. J., Smit, J. J. M., Schinkel, A. H., & Borst, P. (1994) FEBS Lett. 354, 263-266.
58. Southern, P. J., & Berg, P. (1982) J. Mol. Appl. Genet. 1, 327-341.
59. Tang-Wai, D. F., Brossi, A., Arnold, L. D., & Gros, P. (1993) Biochemistry 32, 6470-6476.
60. Tang-Wai, D. F., Kajiji, S., DiCapua, F., de Graaf, D., Roninson, I. B., & Gros, P. (1995) Biochemistry 34, 32-39.
61. van der Blick, A. M., Kooiman, P. M., Schneider, C., & Borst, P. (1988) Gene 71, 401-411.
62. Wigler, M., Pellicer, A., Silverman, S., Axel, R., Urlaub, G., & Chasin, L. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 1373-1376.
63. Zhang, X., Collins. K., & Greenberger, L. M. (1995) J. Biol. Chem. 270, 5441-5448.